@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VS70: (2017-12-06 )
MPNPTDFQSSALATLRIEQQAIDVLATQIDDRFNRACEILLQCKGRVVITGMGKSGHIGRKMAATFASTGTPSFFMHPGEAGHGDLGMLVRGDVLIAISNSGKSDEIMMLMPLIKHLGVPLITISRDDKGPMPQNADIALTLGESDEACPLGLAPTSSTTATLVLGDALAVALLEARGFTADDFARSHPAGALGKRLLLHVKHLMHTGEELPKVSPETPMNQVLYEISNKRLGVTTIVDEQDHLLGIFTDGDLRRLIDKQQGFDVNLPVSEVMTKKPSTISQEARAVEALQQLNQKKISQFVVVDDQNKVIGVISMHDLIQAGVN
Atome Classification :
(20 SA)
.........10........20........30----........40---..----..-.....50........60.......------.70........-80------------......-...90........100.......110....--.--..120.......130...---....140.......150---.......--.160.........170.......180.......190.......200.......210.......220.......230.......240.......250.......260...-....270......-.280.......290.......300.......310.......320...---------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MPNPTDFQSS
A
L
A
T
L
R
I
E
Q
Q
A
I
D
V
L
A
T
Q
I
D
D
----
R
F
N
R
A
C
E
I
L
----
L
Q----CK-G
R
V
V
I
T
GMGKSGHI
G
R
K
M
A
A
T
FAS------TGT
P
S
F
F
MHPG-E-------------AGHGD
L
-
G
M
L
V
RG
D
V
L
I
A
ISNSGKSD
E
I
M
M
L
M
P
L
I
K
H--L--GV
P
L
I
T
I
SRDDKGPMPQN---A
D
I
A
L
T
LGESDEACPL----GLAPTSS--
T
T
--
A
T
L
V
L
G
D
A
L
A
V
A
L
L
E
ARGF
T
A
D
D
F
ARSHP
A
G
A
L
G
K
R
L
L
L
H
V
K
H
L
M
H
T
G
E
ELPKVSPET
P
M
N
Q
V
L
Y
E
ISNKRLG
V
T
T
I
VDEQD
H
L
L
G
I
FTD
G
D
L
R
R
L
I
D
K
QQGFDV-NL
P
V
S
E
V
MTKKPS-
T
I
S
Q
E
A
R
A
V
E
A
L
Q
Q
L
N
Q
K
K
I
S
Q
F
V
V
VDDQN
K
V
I
G
V
I
S
M
H
D
L
I
Q
AGVN---------------------------------------------------
55
HHSearch
86.47
62%
-141
* C2 *
-
2XHZ
-
KDSD_ECOLI
C:
[11-182]
-----
D
F
Q
Q
A
G
K
E
V
L
A
I
E
R
E
C
L
A
E
L
D
Q
Y
I
N
Q
----
N
F
T
L
A
C
E
K
M
----
F
W
----
C
K
-
G
K
V
V
V
M
G
M
G
A
S
G
H
I
G
R
K
M
A
A
T
F
A
S
------
T
G
T
P
S
F
F
V
H
P
G
-
E
-------------
A
A
H
G
D
L
-
G
M
V
T
P
Q
D
V
V
I
A
I
S
N
S
G
E
S
S
E
I
T
A
L
I
P
V
L
K
R
--
L
--
H
V
P
L
I
C
I
T
G
R
P
E
S
S
M
A
R
A
---
A
D
V
H
L
C
V
K
V
A
K
E
A
C
P
L
----
G
L
A
P
T
S
S
--
T
T
--
A
T
L
V
M
G
D
A
L
A
V
A
L
L
K
A
R
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
54
HHSearch
85.70
62%
-143
- C2 -
-
2XHZ
-
KDSD_ECOLI
B:
[11-182]
-----
D
F
Q
Q
A
G
K
E
V
L
A
I
E
R
E
C
L
A
E
L
D
Q
Y
I
N
Q
----
N
F
T
L
A
C
E
K
M
----
F
W
----
C
K
-
G
K
V
V
V
M
G
M
G
A
S
G
H
I
G
R
K
M
A
A
T
F
A
S
------
T
G
T
P
S
F
F
V
H
P
G
-
E
-------------
A
A
H
G
D
L
-
G
M
V
T
P
Q
D
V
V
I
A
I
S
N
S
G
E
S
S
E
I
T
A
L
I
P
V
L
K
R
--
L
--
H
V
P
L
I
C
I
T
G
R
P
E
S
S
M
A
R
A
---
A
D
V
H
L
C
V
K
V
A
K
E
A
C
P
L
----
G
L
A
P
T
S
S
--
T
T
--
A
T
L
V
M
G
D
A
L
A
V
A
L
L
K
A
R
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
85.18
61%
-144
- C2 -
-
2XHZ
-
KDSD_ECOLI
A:
[11-183]
-----
D
F
Q
Q
A
G
K
E
V
L
A
I
E
R
E
C
L
A
E
L
D
Q
Y
I
N
Q
----
N
F
T
L
A
C
E
K
M
----
F
W
----
C
K
-
G
K
V
V
V
M
G
M
G
A
S
G
H
I
G
R
K
M
A
A
T
F
A
S
------
T
G
T
P
S
F
F
V
H
P
G
-
E
-------------
A
A
H
G
D
L
-
G
M
V
T
P
Q
D
V
V
I
A
I
S
N
S
G
E
S
S
E
I
T
A
L
I
P
V
L
K
R
--
L
--
H
V
P
L
I
C
I
T
G
R
P
E
S
S
M
A
R
A
---
A
D
V
H
L
C
V
K
V
A
K
E
A
C
P
L
----
G
L
A
P
T
S
S
--
T
T
--
A
T
L
V
M
G
D
A
L
A
V
A
L
L
K
A
R
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
68.46
32%
-151
- C2 -
-
3FXA
1
?
A:
[31-193]
-----------------------------
E
E
----
A
L
V
K
T
V
E
K
I
----
A
E
----
C
T
-
G
K
I
V
V
A
G
C
G
T
S
G
V
A
A
K
K
L
V
H
S
F
N
C
------
I
E
R
P
A
V
F
L
T
P
S
-
D
-------------
A
V
H
G
T
L
-
G
V
L
Q
K
E
D
I
L
I
L
I
S
K
G
G
N
T
G
E
L
L
N
L
I
P
A
C
K
T
--
K
--
G
S
T
L
I
G
V
T
E
N
P
D
S
V
I
A
K
E
---
A
D
I
F
F
P
V
S
V
S
K
E
P
D
P
F
----
N
M
L
A
T
A
S
--
T
M
--
A
V
I
A
S
F
D
A
V
I
V
C
L
M
T
Y
M
N
Y
T
K
E
Q
F
S
V
I
H
P
G
G
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
67.16
39%
10
- C2 -
-
3ETN
6
?
A:
[28-210]
----------------
L
Q
K
E
A
Q
A
V
L
N
I
P
V
T
D
----
A
Y
E
K
A
V
E
L
I
----
V
E
Q
IHR
K
K
-
G
K
L
V
T
S
G
M
G
K
A
G
Q
I
A
M
N
I
A
T
T
F
C
S
------
T
G
I
P
S
V
F
L
H
P
S
-
E
-------------
A
Q
H
G
D
L
-
G
I
L
Q
E
N
D
L
L
L
L
I
S
N
S
G
K
T
R
E
I
V
E
L
T
Q
L
A
H
N
--
L
NP
G
L
K
F
I
V
I
T
G
N
P
D
S
P
L
A
S
E
---
S
D
V
C
L
S
T
G
H
P
A
E
V
C
T
L
----
G
M
T
P
T
T
S
--
T
T
--
V
M
T
V
I
G
D
I
L
V
V
Q
T
M
K
R
T
E
F
T
I
E
E
Y
S
K
R
H
H
G
G
Y
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
57
HHSearch
63.55
38%
26
- C2 -
-
3ETN
6
?
C:
[24-208]
-------------
I
Q
E
L
L
Q
K
E
A
Q
A
V
L
N
I
P
V
T
D---
A
Y
E
K
A
V
E
L
I
VEQI
H
R
----
K
K
-
G
K
L
V
T
S
G
M
G
K
A
G
Q
I
A
M
N
I
A
T
T
F
C
S
------
T
G
I
P
S
V
F
L
H
P
S
-
E
-------------
A
Q
H
G
D
L
-
G
I
L
Q
E
N
D
L
L
L
L
I
S
N
S
G
K
T
R
E
I
V
E
L
T
Q
L
A
H
N
LN
P
--
G
L
K
F
I
V
I
T
G
N
P
D
S
P
L
A
S
E
---
S
D
V
C
L
S
T
G
H
P
A
E
V
C
T
L
----
G
M
T
P
T
T
S
--
T
T
--
V
M
T
V
I
G
D
I
L
V
V
Q
T
M
K
R
T
E
F
T
I
E
E
Y
S
K
R
H
H
G
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
56
HHSearch
62.91
38%
24
- C2 -
-
3ETN
8
?
B:
[24-208]
-------------
I
Q
E
L
L
Q
K
E
A
Q
A
V
L
N
I
P
V
T
D---
A
Y
E
K
A
V
E
L
I
V
E
Q
I
H
R
----
K
K
-
G
K
L
V
T
S
G
M
G
K
A
G
Q
I
A
M
N
I
A
T
T
F
C
S
------
T
G
I
P
S
V
F
L
H
P
S
-
E
-------------
A
Q
H
G
D
L
-
G
I
L
Q
E
N
D
L
L
L
L
I
S
N
S
G
K
T
R
E
I
V
E
L
T
Q
L
A
H
N
L
N
P
--
G
L
K
F
I
V
I
T
G
N
P
D
S
P
L
A
S
E
---
S
D
V
C
L
S
T
G
H
P
A
E
V
C
T
L
----
G
M
T
P
T
T
S
--
T
T
--
V
M
T
V
I
G
D
I
L
V
V
Q
T
M
K
R
T
E
F
T
I
E
E
Y
S
K
R
H
H
G
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
53
HHSearch
61.81
30%
-22
- C2 -
-
3FXA
1
?
A:
[5-193]
----
Q
A
I
L
D
N
I
H
Q
T
W
Q
E
E
A
N
A
I
S
R
L
P
E
V
T
S
E
E
---
A
L
V
K
T
V
E
K
I
----
A
-----
E
C
T
G
K
I
V
V
A
G
C
G
T
S
G
V
A
A
K
K
L
V
H
S
F
N
C
------
I
E
R
P
A
V
F
L
T
P
S
-
D
-------------
A
V
H
G
T
L
-
G
V
L
Q
K
E
D
I
L
I
L
I
S
K
G
G
N
T
G
E
L
L
N
L
I
P
A
C
K
T
--
K
--
G
S
T
L
I
G
V
T
E
N
P
D
S
V
I
A
K
E
---
A
D
I
F
F
P
V
S
V
S
K
E
P
D
P
F
----
N
M
L
A
T
A
S
--
T
M
--
A
V
I
A
S
F
D
A
V
I
V
C
L
M
T
Y
M
N
Y
T
K
E
Q
F
S
V
I
H
P
G
G
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
61.13
44%
-130
- C1 -
-
3K2V
5
?
A:
[20-149]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
A
L
G
R
K
L
L
L
R
V
N
D
I
M
H
T
G
D
E
I
P
H
V
G
L
Q
A
T
L
R
D
A
L
L
E
I
T
R
K
N
L
G
M
T
A
I
C
D
D
D
M
N
I
I
G
I
F
T
D
G
D
L
R
R
V
F
D
--
T
G
V
D
M
R
D
A
S
I
A
D
V
M
T
R
G
G
I
-
R
I
R
P
G
T
L
A
V
D
A
L
-
N
L
M
Q
S
R
H
I
T
C
V
L
V
A
D
G
D
H
L
L
G
V
V
H
M
H
D
L
L
R
A
------------------------------------------------------
6
PsiBlast_PDB
60.38
39%
-144
- C1 -
-
4O9K
2
?
A:
[1-129]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
R
R
L
L
T
F
V
R
D
I
M
H
T
G
D
D
T
P
V
I
G
L
E
A
S
V
R
D
A
L
L
E
M
T
A
K
K
L
G
M
T
A
I
V
D
G
A
G
T
I
Q
G
V
F
T
D
G
D
L
R
R
L
L
E
K
A
Q
D
I
H
A
-
T
-
P
I
T
A
V
M
T
R
S
C
V
-
T
V
E
G
S
L
L
A
A
E
A
V
R
I
M
E
Q
K
R
I
N
A
L
P
V
V
E
N
-
G
R
L
I
G
A
I
N
M
H
D
L
L
R
A
G
V
----------------------------------------------------
52
HHSearch
60.36
30%
-22
- C2 -
-
3FXA
1
?
D:
[5-191]
----
Q
A
I
L
D
N
I
H
Q
T
W
Q
E
E
A
N
A
I
S
R
L
P
E
V
T
S
E
E---
A
L
V
K
T
V
E
K
I
----
A
-----
E
C
T
G
K
I
V
V
A
G
C
G
T
S
G
V
A
A
K
K
L
V
H
S
F
N
C
------
I
E
R
P
A
V
F
L
T
P
S
-
D
-------------
A
V
H
G
T
L
-
G
V
L
Q
K
E
D
I
L
I
L
I
S
K
G
G
N
T
G
E
L
L
N
L
I
P
A
C
K
T
--
K
--
G
S
T
L
I
G
V
T
E
N
P
D
S
V
I
A
K
E
---
A
D
I
F
F
P
V
S
V
S
K
E
P
D
P
F
----
N
M
L
A
T
A
S
--
T
M
--
A
V
I
A
S
F
D
A
V
I
V
C
L
M
T
Y
M
N
Y
T
K
E
Q
F
S
V
I
H
P
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
60.14
44%
-150
- C1 -
-
3FNA
2
?
A:
[22-147]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
G
R
K
L
L
L
R
V
N
D
I
M
H
T
G
D
E
I
P
H
V
K
K
T
A
S
L
R
D
A
L
L
E
V
T
R
K
N
L
G
M
T
V
I
C
D
D
N
M
M
I
E
G
I
F
T
D
G
D
L
R
R
V
F
D
--------
R
L
S
I
A
D
V
M
T
P
G
G
I
-
R
V
R
P
G
I
L
A
V
E
A
L
N
L
M
Q
S
R
H
I
T
S
-
V
M
V
A
D
G
D
H
L
L
G
V
L
H
M
H
D
L
L
--------------------------------------------------------
62
HHSearch
52.76
19%
-54
- C2 -
-
4IVN
2
?
A:
[92-259]
--------
D
I
C
D
V
S
A
Q
S
A
V
D
S
L
Q
D
T
A
K
L
I
D
R
K
---
S
L
A
R
I
V
E
R
V
----
H
-----
Q
A
-
E
F
I
G
C
I
G
V
G
A
S
S
I
V
G
R
Y
L
A
Y
R
L
I
R
------
I
G
K
K
A
I
M
F
E
D
T
-
H
-------------
L
A
A
M
S
A
-
S
R
S
S
Q
G
D
L
W
F
A
V
S
S
S
G
S
T
K
E
V
I
H
A
A
G
L
A
Y
K
--
R
--
D
I
P
V
V
S
L
T
N
I
N
H
S
P
L
S
S
L
---
S
T
E
M
L
V
A
A
R
P
E
G
P
L
------
T
G
G
A
F
A
S
--
K
V
--
G
A
L
L
L
V
D
V
L
V
N
S
L
L
E
S
Y
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
60
HHSearch
52.63
20%
-45
- C2 -
-
1VIM
2
Y1796_ARCFU
D:
[13-189]
---------
S
L
L
R
F
L
E
V
V
S
E
H
I
K
N
L
R
N
H
I
D
L
E---
T
V
G
E
M
I
K
L
I
----
D
-----
S
A
-
R
S
I
F
V
I
G
A
G
R
S
G
Y
I
A
K
A
F
A
M
R
L
M
H
------
L
G
Y
T
V
Y
V
V
G
E
T
-
V
------------------
T
-
P
R
I
T
D
Q
D
V
L
V
G
I
S
G
S
G
E
T
T
S
V
V
N
I
S
K
K
A
K
D
--
I
--
G
S
K
L
V
A
V
T
G
K
R
D
S
S
L
A
K
M
---
A
D
V
V
M
V
V
K
G
K
M
K
Q
E
R
D
EILS
Q
L
A
P
L
G
T
MF
E
L
--
T
A
M
I
F
L
D
A
L
V
A
E
I
M
M
Q
K
H
L
T
E
K
D
L
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
61
HHSearch
52.12
20%
-41
- C2 -
-
1VIM
1
Y1796_ARCFU
A:
[13-189]
---------
S
L
L
R
F
L
E
V
V
S
E
H
I
K
N
L
R
N
H
I
D
L
E
---
T
V
G
E
M
I
K
L
I
----
D
-----
S
A
-
R
S
I
F
V
I
G
A
G
R
S
G
Y
I
A
K
A
F
A
M
R
L
M
H
------
L
G
Y
T
V
Y
V
V
G
E
T
-
V
------------------
T
-
P
R
I
T
D
Q
D
V
L
V
G
I
S
G
S
G
E
T
T
S
V
V
N
I
S
K
K
A
K
D
--
I
--
G
S
K
L
V
A
V
T
G
K
R
D
S
S
L
A
K
M
---
A
D
V
V
M
V
V
K
G
K
M
K
Q
E
R
D
E
I
L
S
Q
L
A
P
L
G
T
M
F
E
L
--
T
A
M
I
F
L
D
A
L
V
A
E
I
M
M
Q
K
H
L
T
E
K
D
L
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
47.01
38%
-202
- C1 -
-
2P9M
-
Y922_METJA
A:
[7-65]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
I
K
V
K
D
V
M
T
K
N
V
I
-
T
A
K
R
H
E
G
V
V
E
A
F
E
K
M
L
K
Y
K
I
S
S
L
P
V
I
D
D
E
N
K
V
I
G
I
V
T
T
T
D
I
---------------------------------------------------------
82
Fugue
46.89
15%
-124
- C1 -
-
1PVM
-
?
A:
[7-184]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
F
M
R
V
E
K
I
M
N
S
--
N
F
K
T
V
N
W
N
T
T
V
F
D
A
V
K
I
M
N
E
N
H
L
Y
G
L
V
V
K
D
D
N
G
N
D
V
G
L
L
S
E
R
S
I
I
K
R
F
I
P
R
N
K
K
P
D
-
E
V
P
I
R
L
V
M
R
K
P
I
P
-
K
V
K
S
D
Y
D
V
K
D
V
A
A
Y
L
S
E
N
G
L
E
R
C
A
V
V
D
D
P
G
R
V
V
G
I
V
T
L
T
D
L
S
R
Y
L
S
R
A
S
I
T
D
I
L
L
S
H
R
T
K
DYQHLCPKCGV
G
V
L
E
P
V
Y
N
EKGEIK
V
F
R
C
SNPACDYEE
68
HHSearch
46.02
15%
-10
- C2 -
-
1X92
2
GMHA_PSEAE
B:
[7-194]
--------
H
R
I
R
Q
L
F
Q
A
S
I
E
T
K
Q
Q
A
L
E
V
L
P
P
Y
I
E
Q
A
S
L
V
M
V
N
A
L
----
L
-----
N
E
-
G
K
I
L
S
C
G
N
G
G
S
A
G
D
A
Q
H
F
S
S
E
L
L
N
RFERER
P
S
L
P
A
V
A
L
T
T
D
S
S
T
I
T
S
I
A
N
D
YSYNE
V
F
S
K
Q
I
R
A
L
G
Q
P
G
D
V
L
L
A
I
S
T
S
G
N
S
A
N
V
I
Q
A
I
Q
A
A
H
D
--
R
--
E
M
L
V
V
A
L
T
G
R
D
G
G
G
M
A
S
L
LLP
E
D
V
E
I
R
V
P
S
K
I
--------------
T
A
--
R
I
Q
E
V
H
L
L
A
I
H
C
L
C
D
L
I
D
R
Q
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
PsiBlast_CBE
45.87
32%
-160
- C1 -
-
5MCP
2
?
C:
[161-294]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Q
G
I
I
T
S
R
D
I
Q
F
V
E
D
E
-------
T
L
L
V
S
E
I
M
T
K
D
V
I
-
T
G
K
Q
G
I
N
L
E
E
A
N
Q
I
L
K
N
T
K
K
G
K
L
P
I
V
D
E
A
G
C
L
V
S
M
L
S
R
T
D
L
M
K
-------------------------------------------------------
7
PsiBlast_PDB
45.19
20%
-108
- C1 -
-
2NYC
-
AAKG_YEAST
A:
[195-315]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
Q
D
N
M
K
S
C
Q
M
T
T
P
V
I
D
V
I
Q
M
L
T
Q
G
R
V
S
S
V
P
I
I
D
E
N
G
Y
L
I
N
V
Y
E
A
Y
D
V
L
G
L
I
K
G
G
----
L
-
S
L
S
V
G
E
A
L
M
R
R
S
-Y
T
C
T
K
N
D
K
L
S
T
I
M
D
N
I
R
K
A
R
V
H
R
F
F
V
V
D
D
V
G
R
L
V
G
V
L
T
L
S
D
I
L
K
-------------------------------------------------------