@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VSA2: (2017-12-06 )
MSELIMNEKTDLEPQVPSVLPLLALRDVVVYPHMQIALFVGREKSINAVDVARNSDNLVFVVAQKDSLTEEIDHDNLYQYGTVAKIVQVVNHENDENCIKVLIEGLHRSKLKKIIDEDSYLTAEHELSPMTINLDKATQETRLQELRNLFAQYAEAKLRNARELVAAANKIEDLLQLMFFVATRVPLNIEIKQKFLEYDEFEAHLQELMNYLMNQSAEQQIEQTLHDSVKRQMEKNQREYFLNEKMKVIQRELSDMNGGAEDDVAEIEKRLAEADLPEHVRKKAEAEFRKLKAMQPASSEAAVVRNYLEVILDTPWNKASKVSINLNKAQEILDADHYGLDDVKDRIVEYLAVQSRVKKLKGPILCLVGPPGVGKTSLGESVAKATGREFVRMALGGVRDEAEIRGHRRTYIGAMPGKIVQSLTKVGVKNPLFLLDEIDKMAQDYRGDPASALLEVLDPSQNSKFNDHYLDLDLDLSEVMFICTANSMNIPEALLDRMEVIRLPGYTEDEKVNIAERYLVPKAIKNNGLRPKELTIHEEAIRDIVQRYTREAGVRNLEREVSKIARKVVKEAVSKKSKNLQLDVTSANLPEYLGPHKFDFGMAEDEAQVGRVNGLAWTSVGGELLTIEVAAVKGKGKFITTGSLGDVMKESITTAMTVVRTRADELGIEASRFEETDVHVHLPEGATPKDGPSAGLALTTALVSAFTGIAIRPDIAMTGETSLGGRAMRIGGLKEKLLAAHRGGIKLVFIPQDNVRDLAEIPDNVKEGLEIKAVKSIDEILPLALTSMPKPLPKTPIVKPVEGSKAARH
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360--.........370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480......-.-490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690.......700.......710.......720.......730.......740.......750.......760.......770.......780.......790........800.......
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
M
S
E
L
IMNEKTDLEPQV
P
S
V
L
P
L
L
A
L
R
D
V
V
VYPH
M
Q
I
A
L
F
VGREKSI
N
A
V
D
VARNSD
N
L
V
F
V
V
AQKDS
L
T
E
EIDHD
N
L
YQYG
T
V
A
K
I
V
Q
V
V
NHEN
D
E
N
C
I
K
V
L
I
E
G
L
H
R
S
K
L
K
K
I
IDEDS
Y
L
TAEHELS
P
M
T
I
NLDKA
T
Q
E
T
R
L
Q
E
L
R
N
L
F
A
Q
Y
A
E
A
K
L
R
N
A
R
E
L
V
A
A
A
N
K
I
E
D
L
L
Q
L
M
F
F
V
ATRV
P
L
N
I
E
I
K
Q
K
F
L
E
Y
D
E
F
E
A
H
L
Q
E
L
M
N
Y
L
MN
Q
S
A
E
Q
Q
I
E
Q
T
L
H
D
S
V
K
R
Q
M
E
K
N
Q
R
E
Y
F
L
N
E
K
M
K
V
I
Q
R
E
L
S
DMNGGAED
D
V
A
E
I
E
K
R
L
A
EAD
L
P
E
H
V
R
K
K
A
E
A
E
F
R
K
L
KAMQPAS
S
E
A
A
V
V
R
N
Y
L
E
V
I
LDTPWNKA
S
K
V
S
I
N
L
N
K
A
Q
E
I
L
D
ADHY
G
L
D
D
V
K
D
R
I
V
E
Y
L
A
V
Q
S
R
V
K
K
L----KG
P
I
L
C
L
VGPPGVG
K
T
S
L
G
E
S
V
A
K
A
T
G
R
E
F
V
R
M
A
LGGVR
D
E
A
E
IRGHRRTYIGAM
P
G
K
I
V
Q
S
L
T
KVGVKN
P
L
F
L
L
D
E
I
D
K
M
A
Q
D
YRG
D
P
A
S
A
L
L
E
VLDPSQNSKFND
H
Y
L
D
LDL
D
L
S
E
V
M
F
I
C
TANSM-N-
I
P
E
A
L
L
D
R
M
E
V
IRLPGYTED
E
K
V
N
I
A
E
R
YL
V
P
K
A
IKNNGLRP
K
E
L
T
I
H
E
E
A
I
R
D
I
V
Q
R
Y
T
R
E
AG
V
R
N
L
E
R
E
V
S
K
I
A
R
K
V
V
K
E
A
V
S
KKSK
N
L
Q
L
D
V
TSAN
L
P
E
YLGPHKFDFGMAEDEAQVGRVN
G
L
A
W
TSVG
G
E
L
L
T
I
E
V
A
A
VKGK
G
K
F
I
T
TG
S
L
G
D
V
M
K
E
S
I
T
T
A
M
T
V
V
R
T
R
A
D
ELGIEASRFEET
D
V
H
V
HLPEGATPKDGPSA
G
L
A
L
T
T
A
L
V
S
A
F
TG
I
A
IRPDIAMTGETSLGG
R
A
M
RIG
G
L
K
E
K
L
L
A
AHRG
G
I
K
L
V
F
IPQDN
V
R
D
L
A
EI
P
D
N
V
K
EGL
E
I
K
A
V
K
S
I
D
E
I
L
P
L
A
L
TSMPKP-LPKTPIVKPVEGSKAARH
30
PsiBlast_CBE
77.97
52%
6
- C3 -
-
4YPL
2
?
B:
[7-542]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
L
E
A
L
R
K
K
I
E
E
V
G
M
P
E
A
V
K
T
K
A
L
K
E
L
D
R
L
E
R
M
Q
Q
G
S
P
E
A
T
V
A
R
T
Y
L
D
W
L
T
E
V
P
W
S
K
A
D
P
E
V
L
D
I
N
H
T
R
Q
V
L
D
E
D
H
Y
G
L
K
D
V
K
E
R
I
L
E
Y
L
A
V
R
Q
L
T
Q
G
L
DVRN
K
A
P
I
L
V
L
V
G
P
P
G
V
G
K
T
S
L
G
R
S
I
A
R
S
M
N
R
K
F
H
R
I
S
L
G
G
V
R
D
E
A
E
I
R
G
H
R
R
T
Y
I
G
A
M
P
G
K
L
I
H
A
M
K
Q
V
G
V
I
N
P
V
I
L
L
D
Q
I
D
K
M
S
S
D
W
R
G
D
P
A
S
A
M
L
E
V
L
D
P
E
Q
N
N
T
F
T
D
H
Y
L
D
V
P
Y
D
L
S
K
V
F
F
I
T
T
A
N
T
L
Q
T
-
I
P
R
P
L
L
D
R
M
E
V
I
E
I
P
G
Y
T
N
M
E
K
Q
A
I
A
R
Q
Y
L
W
P
K
Q
V
R
E
S
G
M
E
G
R
-
I
E
V
T
D
A
A
I
L
R
V
I
S
E
Y
T
R
E
A
G
V
R
G
L
E
R
E
L
G
K
I
A
R
K
G
A
K
F
W
L
E
G
A
W
E
G
L
R
-
T
I
D
A
S
D
I
P
T
Y
L
G
I
P
R
Y
R
P
D
K
A
E
T
E
P
Q
V
G
T
A
Q
G
L
A
W
T
P
V
G
G
T
L
L
T
I
E
V
A
A
V
P
G
S
G
K
L
S
L
T
G
Q
L
G
E
V
M
K
E
S
A
Q
A
A
L
T
Y
L
R
A
H
T
Q
D
Y
G
L
P
E
D
F
Y
N
K
V
D
L
H
V
H
V
P
D
G
A
T
P
K
D
G
P
S
A
G
I
T
M
A
T
A
I
A
S
A
L
S
R
R
P
A
R
M
D
I
A
M
T
G
E
V
S
L
R
G
K
V
M
P
I
G
G
V
K
E
K
L
L
A
A
H
Q
A
G
I
H
K
I
V
L
P
K
D
N
E
A
Q
L
E
E
L
P
K
E
V
L
E
G
L
E
I
K
L
V
E
D
V
G
E
V
L
E
Y
L
L
--
L
P
E
P
T
M
P
--
P
V
V
-----------
2
PsiBlast_PDB
77.12
52%
8
- C3 -
-
4YPL
1
?
A:
[7-542]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
L
E
A
L
R
K
K
I
E
E
V
G
M
P
E
A
V
K
T
K
A
L
K
E
L
D
R
L
E
R
M
Q
Q
G
S
P
E
A
T
V
A
R
T
Y
L
D
W
L
T
E
V
P
W
S
K
A
D
P
E
V
L
D
I
N
H
T
R
Q
V
L
D
E
D
H
Y
G
L
K
D
V
K
E
R
I
L
E
Y
L
A
V
R
Q
L
T
Q
G
L
DVRN
K
A
P
I
L
V
L
V
G
P
P
G
V
G
K
T
S
L
G
R
S
I
A
R
S
M
N
R
K
F
H
R
I
S
L
G
G
V
R
D
E
A
E
I
R
G
H
R
R
T
Y
I
G
A
M
P
G
K
L
I
H
A
M
K
Q
V
G
V
I
N
P
V
I
L
L
D
Q
I
D
K
M
S
S
D
W
R
G
D
P
A
S
A
M
L
E
V
L
D
P
E
Q
N
N
T
F
T
D
H
Y
L
D
V
P
Y
D
L
S
K
V
F
F
I
T
T
A
N
T
L
Q
T
-
I
P
R
P
L
L
D
R
M
E
V
I
E
I
P
G
Y
T
N
M
E
K
Q
A
I
A
R
Q
Y
L
W
P
K
Q
V
R
E
S
G
M
E
G
R
-
I
E
V
T
D
A
A
I
L
R
V
I
S
E
Y
T
R
E
A
G
V
R
G
L
E
R
E
L
G
K
I
A
R
K
G
A
K
F
W
L
E
G
A
W
E
G
L
R
-
T
I
D
A
S
D
I
P
T
Y
L
G
I
P
R
Y
R
P
D
K
A
E
T
E
P
Q
V
G
T
A
Q
G
L
A
W
T
P
V
G
G
T
L
L
T
I
E
V
A
A
V
P
G
S
G
K
L
S
L
T
G
Q
L
G
E
V
M
K
E
S
A
Q
A
A
L
T
Y
L
R
A
H
T
Q
D
Y
G
L
P
E
D
F
Y
N
K
V
D
L
H
V
H
V
P
D
G
A
T
P
K
D
G
P
S
A
G
I
T
M
A
T
A
I
A
S
A
L
S
R
R
P
A
R
M
D
I
A
M
T
G
E
V
S
L
R
G
K
V
M
P
I
G
G
V
K
E
K
L
L
A
A
H
Q
A
G
I
H
K
I
V
L
P
K
D
N
E
A
Q
L
E
E
L
P
K
E
V
L
E
G
L
E
I
K
L
V
E
D
V
G
E
V
L
E
Y
L
L
--
L
P
E
P
T
M
P
--
P
V
V
-----------
26
PsiBlast_CBE
76.43
52%
15
- C3 -
-
4YPL
2
?
F:
[7-543]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
L
E
A
L
R
K
K
I
E
E
V
G
M
P
E
A
V
K
T
K
A
L
K
E
L
D
R
L
E
R
M
Q
Q
G
S
P
E
A
T
V
A
R
T
Y
L
D
W
L
T
E
V
P
W
S
K
A
D
P
E
V
L
D
I
N
H
T
R
Q
V
L
D
E
D
H
Y
G
L
K
D
V
K
E
R
I
L
E
Y
L
A
V
R
Q
L
T
Q
G
L
DVRN
K
A
P
I
L
V
L
V
G
P
P
G
V
G
K
T
S
L
G
R
S
I
A
R
S
M
N
R
K
F
H
R
I
S
L
G
G
V
R
D
E
A
E
I
R
G
H
R
R
T
Y
I
G
A
M
P
G
K
L
I
H
A
M
K
Q
V
G
V
I
N
P
V
I
L
L
D
Q
I
D
K
M
S
S
D
W
R
G
D
P
A
S
A
M
L
E
V
L
D
P
E
Q
N
N
T
F
T
D
H
Y
L
D
V
P
Y
D
L
S
K
V
F
F
I
T
T
A
N
T
L
Q
T
-
I
P
R
P
L
L
D
R
M
E
V
I
E
I
P
G
Y
T
N
M
E
K
Q
A
I
A
R
Q
Y
L
W
P
K
Q
V
R
E
S
G
M
E
G
R
-
I
E
V
T
D
A
A
I
L
R
V
I
S
E
Y
T
R
E
A
G
V
R
G
L
E
R
E
L
G
K
I
A
R
K
G
A
K
F
W
L
E
G
A
W
E
G
L
R
-
T
I
D
A
S
D
I
P
T
Y
L
G
I
P
R
Y
R
P
D
K
A
E
T
E
P
Q
V
G
T
A
Q
G
L
A
W
T
P
V
G
G
T
L
L
T
I
E
V
A
A
V
P
G
S
G
K
L
S
L
T
G
Q
L
G
E
V
M
K
E
S
A
Q
A
A
L
T
Y
L
R
A
H
T
Q
D
Y
G
L
P
E
D
F
Y
N
K
V
D
L
H
V
H
V
P
D
G
A
T
P
K
D
G
P
S
A
G
I
T
M
A
T
A
I
A
S
A
L
S
R
R
P
A
R
M
D
I
A
M
T
G
E
V
S
L
R
G
K
V
M
P
I
G
G
V
K
E
K
L
L
A
A
H
Q
A
G
I
H
K
I
V
L
P
K
D
N
E
A
Q
L
E
E
L
P
K
E
V
L
E
G
L
E
I
K
L
V
E
D
V
G
E
V
L
E
Y
L
L
--
L
P
E
P
T
M
P
--
P
V
V
Q
----------
28
PsiBlast_CBE
76.37
52%
11
- C3 -
-
4YPL
2
?
D:
[7-542]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
L
E
A
L
R
K
K
I
E
E
V
G
M
P
E
A
V
K
T
K
A
L
K
E
L
D
R
L
E
R
M
Q
Q
G
S
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A
T
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A
R
T
Y
L
D
W
L
T
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V
P
W
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A
D
P
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V
L
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I
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H
T
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V
L
D
E
D
H
Y
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L
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D
V
K
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R
I
L
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Y
L
A
V
R
Q
L
T
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G
L
DVRN
K
A
P
I
L
V
L
V
G
P
P
G
V
G
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T
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L
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F
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V
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V
I
N
P
V
I
L
L
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M
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S
D
W
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G
D
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A
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A
M
L
E
V
L
D
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N
N
T
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T
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H
Y
L
D
V
P
Y
D
L
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K
V
F
F
I
T
T
A
N
T
L
Q
T
-
I
P
R
P
L
L
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M
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Y
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M
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K
Q
A
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A
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Y
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V
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M
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-
I
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A
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L
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G
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L
G
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V
M
K
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A
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A
A
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Y
L
R
A
H
T
Q
D
Y
G
L
P
E
D
F
Y
N
K
V
D
L
H
V
H
V
P
D
G
A
T
P
K
D
G
P
S
A
G
I
T
M
A
T
A
I
A
S
A
L
S
R
R
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A
R
M
D
I
A
M
T
G
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S
L
R
G
K
V
M
P
I
G
G
V
K
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K
L
L
A
A
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Q
A
G
I
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K
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L
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K
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N
E
A
Q
L
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L
P
K
E
V
L
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G
L
E
I
K
L
V
E
D
V
G
E
V
L
E
Y
L
L
--
L
P
E
P
T
M
P
--
P
V
V
-----------
146
Fugue
75.16
52%
15
- C3 -
-
4YPL
1
?
C:
[5-542]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
D
L
E
A
L
R
K
K
I
E
E
V
G
M
P
E
A
V
K
T
K
A
L
K
E
L
D
R
L
E
R
M
Q
Q
G
S
P
E
A
T
V
A
R
T
Y
L
D
W
L
T
E
V
P
W
S
K
A
D
P
E
V
L
D
I
N
H
T
R
Q
V
L
D
E
D
H
Y
G
L
K
D
V
K
E
R
I
L
E
Y
L
A
V
R
Q
L
T
Q
G
L
DVRN
K
A
P
I
L
V
L
V
G
P
P
G
V
G
K
T
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L
G
R
S
I
A
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S
M
N
R
K
F
H
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I
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V
R
D
E
A
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I
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Y
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A
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K
L
I
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Q
V
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V
I
N
P
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I
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Q
I
D
K
M
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S
D
W
R
G
D
P
A
S
A
M
L
E
V
L
D
P
E
Q
N
N
T
F
T
D
H
Y
L
D
V
P
Y
D
L
S
K
V
F
F
I
T
T
A
N
T
L
-
Q
T
I
P
R
P
L
L
D
R
M
E
V
I
E
I
P
G
Y
T
N
M
E
K
Q
A
I
A
R
Q
Y
L
W
P
K
Q
V
R
E
S
G
M
E
G
R
-
I
E
V
T
D
A
A
I
L
R
V
I
S
E
Y
T
R
E
A
G
V
R
G
L
E
R
E
L
G
K
I
A
R
K
G
A
K
F
W
L
E
G
A
W
E
G
L
R
-
T
I
D
A
S
D
I
P
T
Y
L
G
I
P
R
Y
R
P
D
K
A
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T
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P
Q
V
G
T
A
Q
G
L
A
W
T
P
V
G
G
T
L
L
T
I
E
V
A
A
V
P
G
S
G
K
L
S
L
T
G
Q
L
G
E
V
M
K
E
S
A
Q
A
A
L
T
Y
L
R
A
H
T
Q
D
Y
G
L
P
E
D
F
Y
N
K
V
D
L
H
V
H
V
P
D
G
A
T
P
K
D
G
P
S
A
G
I
T
M
A
T
A
I
A
S
A
L
S
R
R
P
A
R
M
D
I
A
M
T
G
E
V
S
L
R
G
K
V
M
P
I
G
G
V
K
E
K
L
L
A
A
H
Q
A
G
I
H
K
I
V
L
P
K
D
N
E
A
Q
L
E
E
L
P
K
E
V
L
E
G
L
E
I
K
L
V
E
D
V
G
E
V
L
E
Y
L
L
L
P
E
P
T
M
-
P
P
V
V
--------------
27
PsiBlast_CBE
74.85
52%
15
- C3 -
-
4YPL
1
?
E:
[7-542]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
L
E
A
L
R
K
K
I
E
E
V
G
M
P
E
A
V
K
T
K
A
L
K
E
L
D
R
L
E
R
M
Q
Q
G
S
P
E
A
T
V
A
R
T
Y
L
D
W
L
T
E
V
P
W
S
K
A
D
P
E
V
L
D
I
N
H
T
R
Q
V
L
D
E
D
H
Y
G
L
K
D
V
K
E
R
I
L
E
Y
L
A
V
R
Q
L
T
Q
G
L
DVRN
K
A
P
I
L
V
L
V
G
P
P
G
V
G
K
T
S
L
G
R
S
I
A
R
S
M
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R
K
F
H
R
I
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L
G
G
V
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A
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A
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P
G
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L
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V
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N
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I
L
L
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Q
I
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K
M
S
S
D
W
R
G
D
P
A
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A
M
L
E
V
L
D
P
E
Q
N
N
T
F
T
D
H
Y
L
D
V
P
Y
D
L
S
K
V
F
F
I
T
T
A
N
T
L
Q
T
-
I
P
R
P
L
L
D
R
M
E
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I
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G
Y
T
N
M
E
K
Q
A
I
A
R
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Y
L
W
P
K
Q
V
R
E
S
G
M
E
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R
-
I
E
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T
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A
A
I
L
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T
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E
A
G
V
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L
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L
G
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I
A
R
K
G
A
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W
L
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A
W
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G
L
R
-
T
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A
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Y
L
G
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Y
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A
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V
G
T
A
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L
A
W
T
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T
L
L
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I
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V
A
A
V
P
G
S
G
K
L
S
L
T
G
Q
L
G
E
V
M
K
E
S
A
Q
A
A
L
T
Y
L
R
A
H
T
Q
D
Y
G
L
P
E
D
F
Y
N
K
V
D
L
H
V
H
V
P
D
G
A
T
P
K
D
G
P
S
A
G
I
T
M
A
T
A
I
A
S
A
L
S
R
R
P
A
R
M
D
I
A
M
T
G
E
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S
L
R
G
K
V
M
P
I
G
G
V
K
E
K
L
L
A
A
H
Q
A
G
I
H
K
I
V
L
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K
D
N
E
A
Q
L
E
E
L
P
K
E
V
L
E
G
L
E
I
K
L
V
E
D
V
G
E
V
L
E
Y
L
L
--
L
P
E
P
T
M
P
--
P
V
V
-----------
29
PsiBlast_CBE
74.49
52%
13
- C3 -
-
4YPL
1
?
C:
[7-542]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
L
E
A
L
R
K
K
I
E
E
V
G
M
P
E
A
V
K
T
K
A
L
K
E
L
D
R
L
E
R
M
Q
Q
G
S
P
E
A
T
V
A
R
T
Y
L
D
W
L
T
E
V
P
W
S
K
A
D
P
E
V
L
D
I
N
H
T
R
Q
V
L
D
E
D
H
Y
G
L
K
D
V
K
E
R
I
L
E
Y
L
A
V
R
Q
L
T
Q
G
L
DVRN
K
A
P
I
L
V
L
V
G
P
P
G
V
G
K
T
S
L
G
R
S
I
A
R
S
M
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R
K
F
H
R
I
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L
G
G
V
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A
E
I
R
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Y
I
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A
M
P
G
K
L
I
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A
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K
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V
I
N
P
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I
L
L
D
Q
I
D
K
M
S
S
D
W
R
G
D
P
A
S
A
M
L
E
V
L
D
P
E
Q
N
N
T
F
T
D
H
Y
L
D
V
P
Y
D
L
S
K
V
F
F
I
T
T
A
N
T
L
Q
T
-
I
P
R
P
L
L
D
R
M
E
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I
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G
Y
T
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E
K
Q
A
I
A
R
Q
Y
L
W
P
K
Q
V
R
E
S
G
M
E
G
R
-
I
E
V
T
D
A
A
I
L
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I
S
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Y
T
R
E
A
G
V
R
G
L
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R
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L
G
K
I
A
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K
G
A
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F
W
L
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G
A
W
E
G
L
R
-
T
I
D
A
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D
I
P
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Y
L
G
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Y
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A
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V
G
T
A
Q
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L
A
W
T
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G
G
T
L
L
T
I
E
V
A
A
V
P
G
S
G
K
L
S
L
T
G
Q
L
G
E
V
M
K
E
S
A
Q
A
A
L
T
Y
L
R
A
H
T
Q
D
Y
G
L
P
E
D
F
Y
N
K
V
D
L
H
V
H
V
P
D
G
A
T
P
K
D
G
P
S
A
G
I
T
M
A
T
A
I
A
S
A
L
S
R
R
P
A
R
M
D
I
A
M
T
G
E
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S
L
R
G
K
V
M
P
I
G
G
V
K
E
K
L
L
A
A
H
Q
A
G
I
H
K
I
V
L
P
K
D
N
E
A
Q
L
E
E
L
P
K
E
V
L
E
G
L
E
I
K
L
V
E
D
V
G
E
V
L
E
Y
L
L
--
L
P
E
P
T
M
P
--
P
V
V
-----------
155
HHSearch
73.63
52%
-27
- C3 -
-
3M6A
1
LON1_BACSU
C:
[8-531]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
E
V
Q
T
L
T
E
K
I
E
E
A
G
M
P
D
H
V
K
E
T
A
L
K
E
L
N
R
Y
E
K
I
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S
S
A
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S
V
I
R
N
Y
I
D
W
L
V
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L
P
W
T
D
E
T
D
D
K
L
D
L
K
E
A
G
R
L
L
D
E
E
H
H
G
L
E
K
V
K
E
R
I
L
E
Y
L
A
V
Q
K
L
T
K
S
L
----
K
G
P
I
L
C
L
A
G
P
P
G
V
G
K
T
S
L
A
K
S
I
A
K
S
L
G
R
K
F
V
R
I
S
L
G
--------------------
G
R
I
I
Q
G
M
K
K
A
G
K
L
N
P
V
F
L
L
D
E
I
D
K
M
S
---------
A
M
L
E
V
L
D
P
E
Q
N
S
S
F
S
D
H
Y
I
E
E
T
F
D
L
S
K
V
L
F
I
A
T
A
N
N
L
A
T
-
I
P
G
P
L
R
D
R
M
E
I
I
N
I
A
G
Y
T
E
I
E
K
L
E
I
V
K
D
H
L
L
P
K
Q
I
K
E
H
G
L
K
K
S
N
L
Q
L
R
D
Q
A
I
L
D
I
I
R
Y
Y
T
R
E
A
G
V
R
S
L
E
R
Q
L
A
A
I
C
R
K
A
A
K
A
I
V
A
E
E
R
--
K
R
I
T
V
T
E
K
N
L
Q
D
F
I
G
K
R
I
F
R
Y
G
Q
A
E
T
E
D
Q
V
G
V
V
T
G
L
A
Y
T
T
V
G
G
D
T
L
S
I
E
V
S
L
S
P
G
K
G
K
L
I
L
T
G
K
L
G
D
V
M
R
E
S
A
Q
A
A
F
S
Y
V
R
S
K
T
E
E
L
G
I
E
P
D
F
H
E
K
Y
D
I
H
I
H
V
P
E
G
A
V
P
K
D
G
P
A
A
G
I
T
M
A
T
A
L
V
S
A
L
T
G
R
A
V
S
R
E
V
G
M
T
G
E
I
T
L
R
G
R
V
L
P
I
G
G
L
K
E
K
A
L
G
A
H
R
A
G
L
T
T
I
I
A
P
K
D
N
E
K
D
I
E
D
I
P
E
S
V
R
E
G
L
T
F
I
L
A
S
H
L
D
E
V
L
E
H
A
L
V
------------------------
22
PsiBlast_CBE
73.43
51%
-27
- C3 -
-
3M6A
1
LON1_BACSU
E:
[7-531]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
G
E
V
Q
T
L
T
E
K
I
E
E
A
G
M
P
D
H
V
K
E
T
A
L
K
E
L
N
R
Y
E
K
I
P
S
S
S
A
E
S
S
V
I
R
N
Y
I
D
W
L
V
A
L
P
W
T
D
E
T
D
D
K
L
D
L
K
E
A
G
R
L
L
D
E
E
H
H
G
L
E
K
V
K
E
R
I
L
E
Y
L
A
V
Q
K
L
T
K
S
L
----
K
G
P
I
L
C
L
A
G
P
P
G
V
G
K
T
S
L
A
K
S
I
A
K
S
L
G
R
K
F
V
R
I
S
L
G
--------------------
G
R
I
I
Q
G
M
K
K
A
G
K
L
N
P
V
F
L
L
D
E
I
D
K
M
S
---------
A
M
L
E
V
L
D
P
E
Q
N
S
S
F
S
D
H
Y
I
E
E
T
F
D
L
S
K
V
L
F
I
A
T
A
N
N
L
A
T
-
I
P
G
P
L
R
D
R
M
E
I
I
N
I
A
G
Y
T
E
I
E
K
L
E
I
V
K
D
H
L
L
P
K
Q
I
K
E
H
G
L
K
K
S
N
L
Q
L
R
D
Q
A
I
L
D
I
I
R
Y
Y
T
R
E
A
G
V
R
S
L
E
R
Q
L
A
A
I
C
R
K
A
A
K
A
I
V
A
E
E
R
K
--
R
I
T
V
T
E
K
N
L
Q
D
F
I
G
K
R
I
F
R
Y
G
Q
A
E
T
E
D
Q
V
G
V
V
T
G
L
A
Y
T
T
V
G
G
D
T
L
S
I
E
V
S
L
S
P
G
K
G
K
L
I
L
T
G
K
L
G
D
V
M
R
E
S
A
Q
A
A
F
S
Y
V
R
S
K
T
E
E
L
G
I
E
P
D
F
H
E
K
Y
D
I
H
I
H
V
P
E
G
A
V
P
K
D
G
P
A
A
G
I
T
M
A
T
A
L
V
S
A
L
T
G
R
A
V
S
R
E
V
G
M
T
G
E
I
T
L
R
G
R
V
L
P
I
G
G
L
K
E
K
A
L
G
A
H
R
A
G
L
T
T
I
I
A
P
K
D
N
E
K
D
I
E
D
I
P
E
S
V
R
E
G
L
T
F
I
L
A
S
H
L
D
E
V
L
E
H
A
L
V
------------------------
21
PsiBlast_CBE
73.38
51%
-28
- C3 -
-
3M6A
1
LON1_BACSU
F:
[7-531]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
G
E
V
Q
T
L
T
E
K
I
E
E
A
G
M
P
D
H
V
K
E
T
A
L
K
E
L
N
R
Y
E
K
I
P
S
S
S
A
E
S
S
V
I
R
N
Y
I
D
W
L
V
A
L
P
W
T
D
E
T
D
D
K
L
D
L
K
E
A
G
R
L
L
D
E
E
H
H
G
L
E
K
V
K
E
R
I
L
E
Y
L
A
V
Q
K
L
T
K
S
L
----
K
G
P
I
L
C
L
A
G
P
P
G
V
G
K
T
S
L
A
K
S
I
A
K
S
L
G
R
K
F
V
R
I
S
L
G
--------------------
G
R
I
I
Q
G
M
K
K
A
G
K
L
N
P
V
F
L
L
D
E
I
D
K
M
S
---------
A
M
L
E
V
L
D
P
E
Q
N
S
S
F
S
D
H
Y
I
E
E
T
F
D
L
S
K
V
L
F
I
A
T
A
N
N
L
A
T
-
I
P
G
P
L
R
D
R
M
E
I
I
N
I
A
G
Y
T
E
I
E
K
L
E
I
V
K
D
H
L
L
P
K
Q
I
K
E
H
G
L
K
K
S
N
L
Q
L
R
D
Q
A
I
L
D
I
I
R
Y
Y
T
R
E
A
G
V
R
S
L
E
R
Q
L
A
A
I
C
R
K
A
A
K
A
I
V
A
E
E
R
K
--
R
I
T
V
T
E
K
N
L
Q
D
F
I
G
K
R
I
F
R
Y
G
Q
A
E
T
E
D
Q
V
G
V
V
T
G
L
A
Y
T
T
V
G
G
D
T
L
S
I
E
V
S
L
S
P
G
K
G
K
L
I
L
T
G
K
L
G
D
V
M
R
E
S
A
Q
A
A
F
S
Y
V
R
S
K
T
E
E
L
G
I
E
P
D
F
H
E
K
Y
D
I
H
I
H
V
P
E
G
A
V
P
K
D
G
P
A
A
G
I
T
M
A
T
A
L
V
S
A
L
T
G
R
A
V
S
R
E
V
G
M
T
G
E
I
T
L
R
G
R
V
L
P
I
G
G
L
K
E
K
A
L
G
A
H
R
A
G
L
T
T
I
I
A
P
K
D
N
E
K
D
I
E
D
I
P
E
S
V
R
E
G
L
T
F
I
L
A
S
H
L
D
E
V
L
E
H
A
L
V
------------------------
1
PsiBlast_PDB
73.05
51%
-25
- C3 -
-
3M6A
1
LON1_BACSU
A:
[7-531]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
G
E
V
Q
T
L
T
E
K
I
E
E
A
G
M
P
D
H
V
K
E
T
A
L
K
E
L
N
R
Y
E
K
I
P
S
S
S
A
E
S
S
V
I
R
N
Y
I
D
W
L
V
A
L
P
W
T
D
E
T
D
D
K
L
D
L
K
E
A
G
R
L
L
D
E
E
H
H
G
L
E
K
V
K
E
R
I
L
E
Y
L
A
V
Q
K
L
T
K
S
L
----
K
G
P
I
L
C
L
A
G
P
P
G
V
G
K
T
S
L
A
K
S
I
A
K
S
L
G
R
K
F
V
R
I
S
L
G
--------------------
G
R
I
I
Q
G
M
K
K
A
G
K
L
N
P
V
F
L
L
D
E
I
D
K
M
S
---------
A
M
L
E
V
L
D
P
E
Q
N
S
S
F
S
D
H
Y
I
E
E
T
F
D
L
S
K
V
L
F
I
A
T
A
N
N
L
A
T
-
I
P
G
P
L
R
D
R
M
E
I
I
N
I
A
G
Y
T
E
I
E
K
L
E
I
V
K
D
H
L
L
P
K
Q
I
K
E
H
G
L
K
K
S
N
L
Q
L
R
D
Q
A
I
L
D
I
I
R
Y
Y
T
R
E
A
G
V
R
S
L
E
R
Q
L
A
A
I
C
R
K
A
A
K
A
I
V
A
E
E
R
K
--
R
I
T
V
T
E
K
N
L
Q
D
F
I
G
K
R
I
F
R
Y
G
Q
A
E
T
E
D
Q
V
G
V
V
T
G
L
A
Y
T
T
V
G
G
D
T
L
S
I
E
V
S
L
S
P
G
K
G
K
L
I
L
T
G
K
L
G
D
V
M
R
E
S
A
Q
A
A
F
S
Y
V
R
S
K
T
E
E
L
G
I
E
P
D
F
H
E
K
Y
D
I
H
I
H
V
P
E
G
A
V
P
K
D
G
P
A
A
G
I
T
M
A
T
A
L
V
S
A
L
T
G
R
A
V
S
R
E
V
G
M
T
G
E
I
T
L
R
G
R
V
L
P
I
G
G
L
K
E
K
A
L
G
A
H
R
A
G
L
T
T
I
I
A
P
K
D
N
E
K
D
I
E
D
I
P
E
S
V
R
E
G
L
T
F
I
L
A
S
H
L
D
E
V
L
E
H
A
L
V
------------------------
24
PsiBlast_CBE
72.99
51%
-26
- C3 -
-
3M6A
1
LON1_BACSU
C:
[7-531]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
G
E
V
Q
T
L
T
E
K
I
E
E
A
G
M
P
D
H
V
K
E
T
A
L
K
E
L
N
R
Y
E
K
I
P
S
S
S
A
E
S
S
V
I
R
N
Y
I
D
W
L
V
A
L
P
W
T
D
E
T
D
D
K
L
D
L
K
E
A
G
R
L
L
D
E
E
H
H
G
L
E
K
V
K
E
R
I
L
E
Y
L
A
V
Q
K
L
T
K
S
L
----
K
G
P
I
L
C
L
A
G
P
P
G
V
G
K
T
S
L
A
K
S
I
A
K
S
L
G
R
K
F
V
R
I
S
L
G
--------------------
G
R
I
I
Q
G
M
K
K
A
G
K
L
N
P
V
F
L
L
D
E
I
D
K
M
S
---------
A
M
L
E
V
L
D
P
E
Q
N
S
S
F
S
D
H
Y
I
E
E
T
F
D
L
S
K
V
L
F
I
A
T
A
N
N
L
A
T
-
I
P
G
P
L
R
D
R
M
E
I
I
N
I
A
G
Y
T
E
I
E
K
L
E
I
V
K
D
H
L
L
P
K
Q
I
K
E
H
G
L
K
K
S
N
L
Q
L
R
D
Q
A
I
L
D
I
I
R
Y
Y
T
R
E
A
G
V
R
S
L
E
R
Q
L
A
A
I
C
R
K
A
A
K
A
I
V
A
E
E
R
K
--
R
I
T
V
T
E
K
N
L
Q
D
F
I
G
K
R
I
F
R
Y
G
Q
A
E
T
E
D
Q
V
G
V
V
T
G
L
A
Y
T
T
V
G
G
D
T
L
S
I
E
V
S
L
S
P
G
K
G
K
L
I
L
T
G
K
L
G
D
V
M
R
E
S
A
Q
A
A
F
S
Y
V
R
S
K
T
E
E
L
G
I
E
P
D
F
H
E
K
Y
D
I
H
I
H
V
P
E
G
A
V
P
K
D
G
P
A
A
G
I
T
M
A
T
A
L
V
S
A
L
T
G
R
A
V
S
R
E
V
G
M
T
G
E
I
T
L
R
G
R
V
L
P
I
G
G
L
K
E
K
A
L
G
A
H
R
A
G
L
T
T
I
I
A
P
K
D
N
E
K
D
I
E
D
I
P
E
S
V
R
E
G
L
T
F
I
L
A
S
H
L
D
E
V
L
E
H
A
L
V
------------------------
25
PsiBlast_CBE
72.80
51%
-24
- C3 -
-
3M6A
1
LON1_BACSU
B:
[7-531]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
G
E
V
Q
T
L
T
E
K
I
E
E
A
G
M
P
D
H
V
K
E
T
A
L
K
E
L
N
R
Y
E
K
I
P
S
S
S
A
E
S
S
V
I
R
N
Y
I
D
W
L
V
A
L
P
W
T
D
E
T
D
D
K
L
D
L
K
E
A
G
R
L
L
D
E
E
H
H
G
L
E
K
V
K
E
R
I
L
E
Y
L
A
V
Q
K
L
T
K
S
L
----
K
G
P
I
L
C
L
A
G
P
P
G
V
G
K
T
S
L
A
K
S
I
A
K
S
L
G
R
K
F
V
R
I
S
L
G
--------------------
G
R
I
I
Q
G
M
K
K
A
G
K
L
N
P
V
F
L
L
D
E
I
D
K
M
S
---------
A
M
L
E
V
L
D
P
E
Q
N
S
S
F
S
D
H
Y
I
E
E
T
F
D
L
S
K
V
L
F
I
A
T
A
N
N
L
A
T
-
I
P
G
P
L
R
D
R
M
E
I
I
N
I
A
G
Y
T
E
I
E
K
L
E
I
V
K
D
H
L
L
P
K
Q
I
K
E
H
G
L
K
K
S
N
L
Q
L
R
D
Q
A
I
L
D
I
I
R
Y
Y
T
R
E
A
G
V
R
S
L
E
R
Q
L
A
A
I
C
R
K
A
A
K
A
I
V
A
E
E
R
K
--
R
I
T
V
T
E
K
N
L
Q
D
F
I
G
K
R
I
F
R
Y
G
Q
A
E
T
E
D
Q
V
G
V
V
T
G
L
A
Y
T
T
V
G
G
D
T
L
S
I
E
V
S
L
S
P
G
K
G
K
L
I
L
T
G
K
L
G
D
V
M
R
E
S
A
Q
A
A
F
S
Y
V
R
S
K
T
E
E
L
G
I
E
P
D
F
H
E
K
Y
D
I
H
I
H
V
P
E
G
A
V
P
K
D
G
P
A
A
G
I
T
M
A
T
A
L
V
S
A
L
T
G
R
A
V
S
R
E
V
G
M
T
G
E
I
T
L
R
G
R
V
L
P
I
G
G
L
K
E
K
A
L
G
A
H
R
A
G
L
T
T
I
I
A
P
K
D
N
E
K
D
I
E
D
I
P
E
S
V
R
E
G
L
T
F
I
L
A
S
H
L
D
E
V
L
E
H
A
L
V
------------------------
145
Fugue
72.60
50%
-25
- C3 -
-
3M6A
1
LON1_BACSU
A:
[7-531]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
G
E
V
Q
T
L
T
E
K
I
E
E
A
G
M
P
D
H
V
K
E
T
A
L
K
E
L
N
R
Y
E
K
I
P
S
S
S
A
E
S
S
V
I
R
N
Y
I
D
W
L
V
A
L
P
W
T
D
E
T
D
D
K
L
D
L
K
E
A
G
R
L
L
D
E
E
H
H
G
L
E
K
V
K
E
R
I
L
E
Y
L
A
V
Q
K
L
T
K
S
L
----
K
G
P
I
L
C
L
A
G
P
P
G
V
G
K
T
S
L
A
K
S
I
A
K
S
L
G
R
K
F
V
R
I
S
L
G
G
--------------------
R
I
I
Q
G
M
K
K
A
G
K
L
N
P
V
F
L
L
D
E
I
D
K
M
---------
S
A
M
L
E
V
L
D
P
E
Q
N
S
S
F
S
D
H
Y
I
E
E
T
F
D
L
S
K
V
L
F
I
A
T
A
N
N
L
A
T
-
I
P
G
P
L
R
D
R
M
E
I
I
N
I
A
G
Y
T
E
I
E
K
L
E
I
V
K
D
H
L
L
P
K
Q
I
K
E
H
G
L
K
K
S
N
L
Q
L
R
D
Q
A
I
L
D
I
I
R
Y
Y
T
R
E
A
G
V
R
S
L
E
R
Q
L
A
A
I
C
R
K
A
A
K
A
I
V
A
E
E
R
K
--
R
I
T
V
T
E
K
N
L
Q
D
F
I
G
K
R
I
F
R
Y
G
Q
A
E
T
E
D
Q
V
G
V
V
T
G
L
A
Y
T
T
V
G
G
D
T
L
S
I
E
V
S
L
S
P
G
K
G
K
L
I
L
T
G
K
L
G
D
V
M
R
E
S
A
Q
A
A
F
S
Y
V
R
S
K
T
E
E
L
G
I
E
P
D
F
H
E
K
Y
D
I
H
I
H
V
P
E
G
A
V
P
K
D
G
P
A
A
G
I
T
M
A
T
A
L
V
S
A
L
T
G
R
A
V
S
R
E
V
G
M
T
G
E
I
T
L
R
G
R
V
L
P
I
G
G
L
K
E
K
A
L
G
A
H
R
A
G
L
T
T
I
I
A
P
K
D
N
E
K
D
I
E
D
I
P
E
S
V
R
E
G
L
T
F
I
L
A
S
H
L
D
E
V
L
E
H
A
L
V
------------------------
23
PsiBlast_CBE
71.79
51%
-27
- C3 -
-
3M6A
1
LON1_BACSU
D:
[7-531]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
G
E
V
Q
T
L
T
E
K
I
E
E
A
G
M
P
D
H
V
K
E
T
A
L
K
E
L
N
R
Y
E
K
I
P
S
S
S
A
E
S
S
V
I
R
N
Y
I
D
W
L
V
A
L
P
W
T
D
E
T
D
D
K
L
D
L
K
E
A
G
R
L
L
D
E
E
H
H
G
L
E
K
V
K
E
R
I
L
E
Y
L
A
V
Q
K
L
T
K
S
L
----
K
G
P
I
L
C
L
A
G
P
P
G
V
G
K
T
S
L
A
K
S
I
A
K
S
L
G
R
K
F
V
R
I
S
L
G
--------------------
G
R
I
I
Q
G
M
K
K
A
G
K
L
N
P
V
F
L
L
D
E
I
D
K
M
S
---------
A
M
L
E
V
L
D
P
E
Q
N
S
S
F
S
D
H
Y
I
E
E
T
F
D
L
S
K
V
L
F
I
A
T
A
N
N
L
A
T
-
I
P
G
P
L
R
D
R
M
E
I
I
N
I
A
G
Y
T
E
I
E
K
L
E
I
V
K
D
H
L
L
P
K
Q
I
K
E
H
G
L
K
K
S
N
L
Q
L
R
D
Q
A
I
L
D
I
I
R
Y
Y
T
R
E
A
G
V
R
S
L
E
R
Q
L
A
A
I
C
R
K
A
A
K
A
I
V
A
E
E
R
K
--
R
I
T
V
T
E
K
N
L
Q
D
F
I
G
K
R
I
F
R
Y
G
Q
A
E
T
E
D
Q
V
G
V
V
T
G
L
A
Y
T
T
V
G
G
D
T
L
S
I
E
V
S
L
S
P
G
K
G
K
L
I
L
T
G
K
L
G
D
V
M
R
E
S
A
Q
A
A
F
S
Y
V
R
S
K
T
E
E
L
G
I
E
P
D
F
H
E
K
Y
D
I
H
I
H
V
P
E
G
A
V
P
K
D
G
P
A
A
G
I
T
M
A
T
A
L
V
S
A
L
T
G
R
A
V
S
R
E
V
G
M
T
G
E
I
T
L
R
G
R
V
L
P
I
G
G
L
K
E
K
A
L
G
A
H
R
A
G
L
T
T
I
I
A
P
K
D
N
E
K
D
I
E
D
I
P
E
S
V
R
E
G
L
T
F
I
L
A
S
H
L
D
E
V
L
E
H
A
L
V
------------------------
156
HHSearch
57.20
49%
-96
- C3 -
-
5E7S
-
?
G:
[491-775]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
G
Y
T
N
M
E
K
Q
A
I
A
R
Q
Y
L
W
P
K
Q
V
R
E
S
G
M
E
G
-
R
I
E
V
T
D
A
A
I
L
R
V
I
S
E
Y
T
R
E
A
G
V
R
G
L
E
R
E
L
G
K
I
A
R
K
G
A
K
F
W
L
E
G
A
W
E
-
G
L
R
T
I
D
A
S
D
I
P
T
Y
L
G
I
P
R
Y
R
P
D
K
A
E
T
E
P
Q
V
G
T
A
Q
G
L
A
W
T
P
V
G
G
T
L
L
T
I
E
V
A
A
V
P
G
S
G
K
L
S
L
T
G
Q
L
G
E
V
M
K
E
S
A
Q
A
A
L
T
Y
L
R
A
H
T
Q
D
Y
G
L
P
E
D
F
Y
N
K
V
D
L
H
V
H
V
P
D
G
A
T
P
K
D
G
P
S
A
G
I
T
M
A
T
A
I
A
S
A
L
S
R
R
P
A
R
M
D
I
A
M
T
G
E
V
S
L
R
G
K
V
M
P
I
G
G
V
K
E
K
L
L
A
A
H
Q
A
G
I
H
K
I
V
L
P
K
D
N
E
A
Q
L
E
E
L
P
K
E
V
L
E
G
L
E
I
K
L
V
E
D
V
G
E
V
L
E
Y
L
L
L
P
E
P
T
--------------------
5
PsiBlast_PDB
56.46
48%
-93
- C3 -
-
5E7S
-
?
A:
[492-774]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
Y
T
N
M
E
K
Q
A
I
A
R
Q
Y
L
W
P
K
Q
V
R
E
S
G
M
E
G
R
-
I
E
V
T
D
A
A
I
L
R
V
I
S
E
Y
T
R
E
A
G
V
R
G
L
E
R
E
L
G
K
I
A
R
K
G
A
K
F
W
L
E
G
A
W
E
G
L
R
-
T
I
D
A
S
D
I
P
T
Y
L
G
I
P
R
Y
R
P
D
K
A
E
T
E
P
Q
V
G
T
A
Q
G
L
A
W
T
P
V
G
G
T
L
L
T
I
E
V
A
A
V
P
G
S
G
K
L
S
L
T
G
Q
L
G
E
V
M
K
E
S
A
Q
A
A
L
T
Y
L
R
A
H
T
Q
D
Y
G
L
P
E
D
F
Y
N
K
V
D
L
H
V
H
V
P
D
G
A
T
P
K
D
G
P
S
A
G
I
T
M
A
T
A
I
A
S
A
L
S
R
R
P
A
R
M
D
I
A
M
T
G
E
V
S
L
R
G
K
V
M
P
I
G
G
V
K
E
K
L
L
A
A
H
Q
A
G
I
H
K
I
V
L
P
K
D
N
E
A
Q
L
E
E
L
P
K
E
V
L
E
G
L
E
I
K
L
V
E
D
V
G
E
V
L
E
Y
L
L
--
L
P
E
P
-------------------
4
PsiBlast_PDB
56.19
48%
-93
- C3 -
-
4YPM
3
?
A:
[1-290]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
G
Y
T
N
M
E
K
Q
A
I
A
R
Q
Y
L
W
P
K
Q
V
R
E
S
G
M
E
G
R
-
I
E
V
T
D
A
A
I
L
R
V
I
S
E
Y
T
R
E
A
G
V
R
G
L
E
R
E
L
G
K
I
A
R
K
G
A
K
F
W
L
E
G
A
W
E
G
L
R
-
T
I
D
A
S
D
I
P
T
Y
L
G
I
P
R
Y
R
P
D
K
A
E
T
E
P
Q
V
G
T
A
Q
G
L
A
W
T
P
V
G
G
T
L
L
T
I
E
V
A
A
V
P
G
S
G
K
L
S
L
T
G
Q
L
G
E
V
M
K
E
S
A
Q
A
A
L
T
Y
L
R
A
H
T
Q
D
Y
G
L
P
E
D
F
Y
N
K
V
D
L
H
V
H
V
P
D
G
A
T
P
K
D
G
P
S
A
G
I
T
M
A
T
A
I
A
S
A
L
S
R
R
P
A
R
M
D
I
A
M
T
G
E
V
S
L
R
G
K
V
M
P
I
G
G
V
K
E
K
L
L
A
A
H
Q
A
G
I
H
K
I
V
L
P
K
D
N
E
A
Q
L
E
E
L
P
K
E
V
L
E
G
L
E
I
K
L
V
E
D
V
G
E
V
L
E
Y
L
L
--
L
P
E
P
T
M
P
--
P
V
V
-----------
157
HHSearch
55.88
49%
-92
* C3 *
-
4YPM
3
?
A:
[1-285]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
G
Y
T
N
M
E
K
Q
A
I
A
R
Q
Y
L
W
P
K
Q
V
R
E
S
G
M
E
G
-
R
I
E
V
T
D
A
A
I
L
R
V
I
S
E
Y
T
R
E
A
G
V
R
G
L
E
R
E
L
G
K
I
A
R
K
G
A
K
F
W
L
E
G
A
W
E
-
G
L
R
T
I
D
A
S
D
I
P
T
Y
L
G
I
P
R
Y
R
P
D
K
A
E
T
E
P
Q
V
G
T
A
Q
G
L
A
W
T
P
V
G
G
T
L
L
T
I
E
V
A
A
V
P
G
S
G
K
L
S
L
T
G
Q
L
G
E
V
M
K
E
S
A
Q
A
A
L
T
Y
L
R
A
H
T
Q
D
Y
G
L
P
E
D
F
Y
N
K
V
D
L
H
V
H
V
P
D
G
A
T
P
K
D
G
P
S
A
G
I
T
M
A
T
A
I
A
S
A
L
S
R
R
P
A
R
M
D
I
A
M
T
G
E
V
S
L
R
G
K
V
M
P
I
G
G
V
K
E
K
L
L
A
A
H
Q
A
G
I
H
K
I
V
L
P
K
D
N
E
A
Q
L
E
E
L
P
K
E
V
L
E
G
L
E
I
K
L
V
E
D
V
G
E
V
L
E
Y
L
L
L
P
E
P
T
--------------------
11
PsiBlast_PDB
54.64
62%
-131
- C3 -
-
1RRE
-
LON_ECOLI
A:
[10-191]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
V
G
Q
V
T
G
L
A
W
T
E
V
G
G
D
L
L
T
I
E
T
A
C
V
P
G
K
G
K
L
T
Y
T
G
S
L
G
E
V
M
Q
E
S
I
Q
A
A
L
T
V
V
R
A
R
A
E
K
L
G
I
N
P
D
F
Y
E
K
R
D
I
H
V
H
V
P
E
G
A
T
P
K
D
G
P
A
A
G
I
A
M
C
T
A
L
V
S
C
L
T
G
N
P
V
R
A
D
V
A
M
T
G
E
I
T
L
R
G
Q
V
L
P
I
G
G
L
K
E
K
L
L
A
A
H
R
G
G
I
K
T
V
L
I
P
F
E
N
K
R
D
L
E
E
I
P
D
N
V
I
A
D
L
D
I
H
P
V
K
R
I
E
E
V
L
T
L
A
L
Q
N
E
P
---------------------