@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VT26: (2017-12-11 )
MSKVKTVYRCEQCGADHLKWAGQCSECGEWNCLNEVKLEPTTAHRARPKVGGYAGQVANITTLNKVSVSHETRLPTGISEFDRVLGGGLVTGSVVLIGGDPGIGKSTILLQTATHMASAKSSALYITGEESLSQVALRAQRLDLPTDQLKVMAETCVERICEVLEQERPVVAILDSIQTLYTETLQSAPGGVSQIRESAALLTRYAKNSGTALFIVGHVTKEGALAGPRVLEHMVDCVLYFEGQSDSRYRMIRAVKNRFGAVNELGVFGMTDKGLREVANPSAIFLSRYDEAIPGSIVMISREGTRPLLVEVQALVDDAQGQPRRVALGLEQNRLNMLLAVMHRHGGVQTTGQDVYVNIVGGLKITETGSDLAVLLACASSLRTKALPQQLAVFGEVGLSGEIRPVPNGQERLKEAAKHGFKYVILPRGNAPQKAIPGVQVIAVARLHEALTEAMQLSDELT
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110......------.120........130-........140...----....150--------------------.........-------160.......170.......180......---.190.......200.......210........220.......230.......240....--...250......-.260.......270.......280...------------....290...------....300..--.....310.......-320.-.......330.----.----......340--------..---..-.----------...--350-----.......---------------------.360........370.......380.......390.......400.......410.......420.......430.------.----.-...-.440...-----....450.......460-------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MSK
V
K
T
V
Y
R
C
E
QCGA
D
H
L
K
W
A
GQCSECGEWNCLN
E
V
KLEPTTAHRARPKVGGYAGQ
V
A
N
I
T
T
L
N
K
V
S
VSHETRLPT
G
I
S
E
F
D
R
V
LGGG
L
V
T
G
S
V
V
L
IGGDPGIGK
S
T
I
L
L
QT
A
T
H
MAS------AK-S
S
A
L
Y
I
TG
E
E
S
--
L
S
Q
V
A
L
R
A
Q
RLDL
P
----
T
D
Q
L
K
----------------------
V
M
A
E
T
C
V
E
R
-------
I
C
E
V
L
E
QER
P
V
V
A
I
L
D
S
I
Q
T
L
Y
T
E
T
L
Q
SA---PG
G
V
S
Q
I
R
E
S
A
A
L
L
T
R
Y
AKNSG-
T
A
L
F
I
V
G
HVTKEGALA
G
P
R
V
L
E
H
M
V
D
C
V
L
Y
F
EGQSD--
S
R
Y
R
M
I
R
A
V
K
N
R-FGAVNELGVFGM
T
D
K
G
L
R
E
VANP
S
A
I
F
------------
L
S
R
YDEAIPG------
S
I
V
M
I
SREG--TR
P
L
L
V
E
V
Q
A
L
V
DDA-Q-GQ-P
R
R
V
A
LGL
E
-
Q
----
N
----
R
L
N
M
L
L
A
V
---------
M
H
---RH-G----------GVQ--T-T-----G
Q
D
V
Y
V
N
---------------------
I
V-G
G
L
K
I
TETG
S
D
L
A
V
L
L
A
C
A
S
S
L
R
T
K
A
L
P
Q
Q
L
A
V
F
GEVGLSGEIRPVP
N
G
Q
E
R
L
K
E
A
A
KHG
F
K
Y
V
I
L
PRGNAPQ------K----A-IPG-
V
Q
V
I
A
V
A
-----
R
L
H
E
A
L
T
E
A
M
Q
L
SDELT-------------
23
HHSearch
88.38
43%
-73
- C1 -
-
5LKM
2
?
C:
[66-452]
---------------------------------------------------------------------
N
V
N
R
T
K
T
E
M
E
E
F
N
R
V
L
G
G
G
V
V
P
G
S
L
V
L
I
G
G
D
P
G
I
G
K
S
T
L
L
L
Q
V
S
T
Q
L
S
-------
Q
V
-
G
T
V
L
Y
V
S
G
E
E
S
--
A
Q
Q
I
K
L
R
A
E
R
L
G
D
I
----
D
S
E
F
Y
----------------------
L
Y
A
E
T
N
M
Q
S
-------
V
R
A
E
V
E
R
I
Q
P
D
F
L
I
I
D
S
I
Q
T
I
M
S
P
----------
S
V
S
Q
V
R
E
V
T
A
E
L
M
Q
L
A
K
T
N
N
-
I
A
I
F
I
V
G
H
V
T
-------
P
R
M
L
E
H
M
V
D
T
V
L
Y
F
E
G
E
R
H
--
H
T
F
R
I
L
R
A
V
K
N
R
-
F
G
S
T
N
E
I
G
I
F
E
M
Q
S
G
G
L
V
E
V
L
N
P
S
Q
V
F
------------
L
E
E
R
L
D
G
A
T
G
------
S
S
I
V
V
T
M
E
G
--
T
R
P
I
L
A
E
V
Q
A
L
V
T
P
T
-
M
-
F
G
N
A
K
R
T
T
T
G
L
D
-
F
----
N
----
R
A
S
L
I
M
A
V
---------
L
E
---
K
R
-
A
----------
G
L
L
--
L
-
Q
-----
N
Q
D
A
Y
L
K
---------------------
S
A
-
G
G
V
K
L
D
E
P
A
I
D
L
A
V
A
V
A
I
A
S
S
Y
K
D
K
P
T
N
P
Q
E
C
F
V
G
E
L
G
L
T
G
E
I
R
R
V
N
R
I
E
Q
R
I
N
E
A
A
K
L
G
F
T
K
I
Y
V
P
K
N
S
L
T
G
I
-----
T
----
L
-
P
K
E
-
I
Q
V
I
G
V
T
-----
T
I
Q
E
V
L
K
K
V
F
--------------------
24
HHSearch
87.52
43%
-70
- C1 -
-
5LKM
1
?
A:
[53-452]
--------------------------------------------------------
K
T
K
P
M
K
L
A
E
V
T
S
I
N
V
N
R
T
K
T
E
M
E
E
F
N
R
V
L
G
G
G
V
V
P
G
S
L
V
L
I
G
G
D
P
G
I
G
K
S
T
L
L
L
Q
V
S
T
Q
L
S
Q
-------
V
-
G
T
V
L
Y
V
S
G
E
E
S
--
A
Q
Q
I
K
L
R
A
E
R
L
G
D
I
----
D
S
E
F
Y
----------------------
L
Y
A
E
T
N
M
Q
S
-------
V
R
A
E
V
E
R
I
Q
P
D
F
L
I
I
D
S
I
Q
T
I
M
S
P
E
---------
S
V
S
Q
V
R
E
V
T
A
E
L
M
Q
L
A
K
T
N
N
-
I
A
I
F
I
V
G
H
V
T
K
E
----
G
P
R
M
L
E
H
M
V
D
T
V
L
Y
F
E
G
E
R
H
--
H
T
F
R
I
L
R
A
V
K
N
R
-
F
G
S
T
N
E
I
G
I
F
E
M
Q
S
G
G
L
V
E
V
L
N
P
S
Q
V
F
------------
L
E
E
R
L
D
G
A
T
G
------
S
S
I
V
V
T
M
E
G
--
T
R
P
I
L
A
E
V
Q
A
L
V
T
P
T
-
M
-
F
G
N
A
K
R
T
T
T
G
L
D
-
F
----
N
----
R
A
S
L
I
M
A
V
---------
L
E
---
K
R
-
A
----------
G
L
L
--
L
-
Q
-----
N
Q
D
A
Y
L
K
---------------------
S
A
-
G
G
V
K
L
D
E
P
A
I
D
L
A
V
A
V
A
I
A
S
S
Y
K
D
K
P
T
N
P
Q
E
C
F
V
G
E
L
G
L
T
G
E
I
R
R
V
N
R
I
E
Q
R
I
N
E
A
A
K
L
G
F
T
K
I
Y
V
P
K
N
S
L
T
G
I
-----
T
----
L
-
P
K
E
-
I
Q
V
I
G
V
T
-----
T
I
Q
E
V
L
K
K
V
F
--------------------
21
PsiBlast_CBE
87.41
42%
-74
* C1 *
-
5LKM
2
?
C:
[66-452]
------------------------------------------------------------------
N
V
N
---
R
T
K
T
E
M
E
E
F
N
R
V
L
G
G
G
V
V
P
G
S
L
V
L
I
G
G
D
P
G
I
G
K
S
T
L
L
L
Q
V
S
T
Q
L
S
Q
------
V
--
G
T
V
L
Y
V
S
G
E
E
S
--
A
Q
Q
I
K
L
R
A
E
R
L
G
D
I
----
D
S
E
F
Y
----------------------
L
Y
A
E
T
N
M
Q
S
-------
V
R
A
E
V
E
R
I
Q
P
D
F
L
I
I
D
S
I
Q
T
I
M
S
P
----------
S
V
S
Q
V
R
E
V
T
A
E
L
M
Q
L
A
K
T
N
N
-
I
A
I
F
I
V
G
H
V
T
-------
P
R
M
L
E
H
M
V
D
T
V
L
Y
F
E
G
E
R
H
--
H
T
F
R
I
L
R
A
V
K
N
R
-
F
G
S
T
N
E
I
G
I
F
E
M
Q
S
G
G
L
V
E
V
L
N
P
S
Q
V
F
------------
L
E
E
R
L
D
G
A
T
G
------
S
S
I
V
V
T
M
E
G
--
T
R
P
I
L
A
E
V
Q
A
L
V
T
P
T
-
M
F
G
N
-
A
K
R
T
T
T
G
L
D
-
F
----
N
----
R
A
S
L
I
M
A
V
---------
L
E
---
K
R
-
A
----------
G
L
L
--
L
-
Q
-----
N
Q
D
A
Y
L
K
---------------------
S
A
-
G
G
V
K
L
D
E
P
A
I
D
L
A
V
A
V
A
I
A
S
S
Y
K
D
K
P
T
N
P
Q
E
C
F
V
G
E
L
G
L
T
G
E
I
R
R
V
N
R
I
E
Q
R
I
N
E
A
A
K
L
G
F
T
K
I
Y
V
P
K
N
S
L
T
G
------
I
----
T
-
L
P
K
E
I
Q
V
I
G
V
T
-----
T
I
Q
E
V
L
K
K
V
F
--------------------
1
PsiBlast_PDB
87.17
42%
-73
- C1 -
-
5LKM
1
?
A:
[53-452]
-----------------------------------------------------
K
T
K
P
M
K
L
A
E
V
T
S
I
N
V
N
---
R
T
K
T
E
M
E
E
F
N
R
V
L
G
G
G
V
V
P
G
S
L
V
L
I
G
G
D
P
G
I
G
K
S
T
L
L
L
Q
V
S
T
Q
L
S
Q
------
V
--
G
T
V
L
Y
V
S
G
E
E
S
--
A
Q
Q
I
K
L
R
A
E
R
L
G
D
I
----
D
S
E
F
Y
----------------------
L
Y
A
E
T
N
M
Q
S
-------
V
R
A
E
V
E
R
I
Q
P
D
F
L
I
I
D
S
I
Q
T
I
M
S
P
E
---------
S
V
S
Q
V
R
E
V
T
A
E
L
M
Q
L
A
K
T
N
N
-
I
A
I
F
I
V
G
H
V
T
K
E
----
G
P
R
M
L
E
H
M
V
D
T
V
L
Y
F
E
G
E
R
H
--
H
T
F
R
I
L
R
A
V
K
N
R
-
F
G
S
T
N
E
I
G
I
F
E
M
Q
S
G
G
L
V
E
V
L
N
P
S
Q
V
F
------------
L
E
E
R
L
D
G
A
T
G
------
S
S
I
V
V
T
M
E
G
--
T
R
P
I
L
A
E
V
Q
A
L
V
T
P
T
-
M
F
G
N
-
A
K
R
T
T
T
G
L
D
-
F
----
N
----
R
A
S
L
I
M
A
V
---------
L
E
---
K
R
-
A
----------
G
L
L
--
L
-
Q
-----
N
Q
D
A
Y
L
K
---------------------
S
A
-
G
G
V
K
L
D
E
P
A
I
D
L
A
V
A
V
A
I
A
S
S
Y
K
D
K
P
T
N
P
Q
E
C
F
V
G
E
L
G
L
T
G
E
I
R
R
V
N
R
I
E
Q
R
I
N
E
A
A
K
L
G
F
T
K
I
Y
V
P
K
N
S
L
T
G
------
I
----
T
-
L
P
K
E
I
Q
V
I
G
V
T
-----
T
I
Q
E
V
L
K
K
V
F
--------------------
22
PsiBlast_CBE
83.31
42%
-77
- C1 -
-
5LKM
1
?
B:
[54-452]
------------------------------------------------------
T
K
P
M
K
L
A
E
V
T
----
N
---
R
T
K
T
E
M
E
E
F
N
R
V
L
G
G
G
V
V
P
G
S
L
V
L
I
G
G
D
P
G
I
G
K
S
T
L
L
L
Q
V
S
T
Q
L
--------------
L
Y
V
S
G
E
E
S
--
A
Q
Q
I
K
L
R
A
E
R
L
--------
S
E
F
Y
----------------------
L
----
N
M
Q
S
-------
V
R
A
E
V
E
R
I
Q
P
D
F
L
I
I
D
S
I
Q
--------------
G
S
V
S
Q
V
R
E
V
T
A
E
L
M
Q
L
A
K
T
N
N
-
I
A
I
F
I
V
G
H
V
-------------------
L
Y
F
E
G
-------
F
R
I
L
R
A
V
K
N
R
-
F
G
S
T
N
E
I
G
I
F
E
M
Q
S
G
G
L
V
E
V
L
N
P
S
Q
V
F
------------
L
E
E
R
L
D
G
A
T
G
------
S
S
I
V
V
T
M
E
G
--
T
R
P
I
L
A
E
V
Q
A
L
V
T
P
T
-
M
F
G
N
-
A
K
R
T
T
T
G
L
D
-
F
----
N
----
R
A
S
L
I
M
A
V
---------
L
E
---
K
R
-
A
----------
G
L
L
--
L
-
Q
-----
N
Q
D
A
Y
L
K
---------------------
S
A
-
G
G
V
K
L
D
E
P
A
I
D
L
A
V
A
V
A
I
A
S
S
Y
K
D
K
P
T
N
P
Q
E
C
F
V
G
E
L
G
L
T
G
E
I
R
R
V
N
R
I
E
Q
R
I
N
E
A
A
K
L
G
F
T
K
I
Y
V
P
K
N
S
L
T
G
------
I
----
T
-
L
P
K
E
I
Q
V
I
G
V
T
-----
T
I
Q
E
V
L
K
K
V
F
--------------------
3
PsiBlast_PDB
46.13
43%
-59
- C1 -
-
5H45
-
?
A:
[33-171]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
V
P
G
------
S
A
V
A
L
A
L
A
G
--
E
R
A
L
A
L
E
V
Q
A
L
A
A
K
T
-
P
F
P
A
-
P
R
R
V
V
Q
G
L
D
-
G
----
R
----
R
V
D
V
V
L
A
V
---------
L
E
---
R
R
-
L
----------
G
L
P
--
L
-
A
-----
N
L
D
V
Y
V
N
---------------------
L
A
-
G
G
L
K
V
Q
D
P
G
L
D
L
A
V
A
L
A
V
Y
S
A
V
V
G
R
P
L
P
A
D
L
A
L
V
G
E
V
G
L
A
G
E
V
R
R
V
A
G
L
E
R
R
L
R
E
G
E
R
A
G
F
G
R
F
L
H
P
-
G
N
--------------------------------------------------------------
27
HHSearch
45.54
40%
-56
- C1 -
-
5H45
-
?
A:
[33-174]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
V
P
G
------
S
A
V
A
L
A
L
A
G
--
E
R
A
L
A
L
E
V
Q
A
L
A
A
K
T
-
P
-
F
P
A
P
R
R
V
V
Q
G
L
D
-
G
----
R
----
R
V
D
V
V
L
A
V
---------
L
E
---
R
R
-
L
----------
G
L
P
--
L
-
A
-----
N
L
D
V
Y
V
N
---------------------
L
A
-
G
G
L
K
V
Q
D
P
G
L
D
L
A
V
A
L
A
V
Y
S
A
V
V
G
R
P
L
P
A
D
L
A
L
V
G
E
V
G
L
A
G
E
V
R
R
V
A
G
L
E
R
R
L
R
E
G
E
R
A
G
F
G
R
F
L
H
P
G
N
L
K
R
------------------------------------------------------------
2
PsiBlast_PDB
42.88
38%
-23
- C1 -
-
5LKQ
-
?
A:
[23-198]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
Q
V
F
------------
L
E
E
R
L
D
G
A
T
G
------
S
S
I
V
V
T
M
E
G
--
T
R
P
I
L
A
E
V
Q
A
L
V
T
P
T
-
M
F
G
N
-
A
K
R
T
T
T
G
L
D
-
F
----
N
----
R
A
S
L
I
M
A
V
---------
L
E
---
K
R
-
A
----------
G
L
L
--
L
-
Q
-----
N
Q
D
A
Y
L
K
---------------------
S
A
-
G
G
V
K
L
D
E
P
A
I
D
L
A
V
A
V
A
I
A
S
S
Y
K
D
K
P
T
N
P
Q
E
C
F
V
G
E
L
G
L
T
G
E
I
R
R
V
N
R
I
E
Q
R
I
N
E
A
A
K
L
G
F
T
K
I
Y
V
P
K
N
S
L
T
G
------
I
----
T
-
L
P
K
E
I
Q
V
I
G
V
T
-----
T
I
Q
E
V
L
K
K
V
F
--------------------
28
HHSearch
42.69
40%
-55
- C1 -
-
5H45
-
?
B:
[28-174]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
E
R
P
L
G
V
P
G
------
S
A
V
A
L
A
L
A
G
--
E
R
A
L
A
L
E
V
Q
A
L
A
A
K
T
-
P
-
F
P
A
P
R
R
V
V
Q
G
L
D
-
G
----
R
----
R
V
D
V
V
L
A
V
---------
L
E
---
R
R
-
L
----------
G
L
P
--
L
-
A
-----
N
L
D
V
Y
V
N
---------------------
L
A
-
G
G
L
K
V
Q
D
P
G
L
D
L
A
V
A
L
A
V
Y
S
A
V
V
G
R
P
L
P
A
D
L
A
L
V
G
E
V
G
L
A
G
E
V
R
R
V
A
G
L
E
R
R
L
R
E
G
E
R
A
G
F
G
R
F
L
H
P
G
N
L
K
R
------------------------------------------------------------
12
PsiBlast_PDB
42.58
31%
-106
- C1 -
-
1XHK
-
LONB_METJA
A:
[92-187]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
I
D
G
D
S
A
T
A
A
V
C
L
A
I
I
S
A
L
L
D
I
P
L
K
Q
D
F
A
I
T
G
S
L
D
L
S
G
N
V
L
A
I
G
G
V
N
E
K
I
E
A
A
K
R
Y
G
F
K
R
V
I
I
P
E
A
N
M
I
D
------
V
----
I
E
T
E
G
-
I
E
I
I
P
V
K
-----
T
L
D
E
I
V
P
L
V
F
D
L
D
-----------------
26
HHSearch
42.29
36%
-22
- C1 -
-
5LKQ
-
?
A:
[23-198]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
Q
V
F
------------
L
E
E
R
L
D
G
A
T
G
------
S
S
I
V
V
T
M
E
G
--
T
R
P
I
L
A
E
V
Q
A
L
V
T
P
T
-
M
-
F
G
N
A
K
R
T
T
T
G
L
D
-
F
----
N
----
R
A
S
L
I
M
A
V
---------
L
E
---
K
R
-
A
----------
G
L
L
--
L
-
Q
-----
N
Q
D
A
Y
L
K
---------------------
S
A
-
G
G
V
K
L
D
E
P
A
I
D
L
A
V
A
V
A
I
A
S
S
Y
K
D
K
P
T
N
P
Q
E
C
F
V
G
E
L
G
L
T
G
E
I
R
R
V
N
R
I
E
Q
R
I
N
E
A
A
K
L
G
F
T
K
I
Y
V
P
K
N
S
L
T
G
I
-----
T
----
L
-
P
K
E
-
I
Q
V
I
G
V
T
-----
T
I
Q
E
V
L
K
K
V
F
--------------------
25
HHSearch
39.77
36%
-17
- C1 -
-
5LKQ
-
?
B:
[22-198]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
S
Q
V
F
------------
L
E
E
R
L
D
G
A
T
G
------
S
S
I
V
V
T
M
E
G
--
T
R
P
I
L
A
E
V
Q
A
L
V
T
P
T
-
M
-
F
G
N
A
K
R
T
T
T
G
L
D
-
F
----
N
----
R
A
S
L
I
M
A
V
---------
L
E
---
K
R
-
A
----------
G
L
L
--
L
-
Q
-----
N
Q
D
A
Y
L
K
---------------------
S
A
-
G
G
V
K
L
D
E
P
A
I
D
L
A
V
A
V
A
I
A
S
S
Y
K
D
K
P
T
N
P
Q
E
C
F
V
G
E
L
G
L
T
G
E
I
R
R
V
N
R
I
E
Q
R
I
N
E
A
A
K
L
G
F
T
K
I
Y
V
P
K
N
S
L
T
G
I
-----
T
----
L
-
P
K
E
-
I
Q
V
I
G
V
T
-----
T
I
Q
E
V
L
K
K
V
F
--------------------
49
Fugue
39.61
16%
-23
- C1 -
-
1TF7
4
KAIC_SYNE7
A:
[14-497]
------------------------------------------------------------------
E
H
Q
A
I
A
K
M
R
T
M
I
E
G
F
D
D
I
S
H
G
G
L
P
I
G
R
S
T
L
V
S
G
T
S
G
T
G
K
T
L
F
S
I
Q
F
L
Y
N
G
I
I
------
E
F
D
E
P
G
V
F
V
T
F
E
E
T
--
P
Q
D
I
I
K
N
A
R
S
F
G
W
D
----
L
A
K
L
V
D
E
GK
L
F
I
L
D
ASPDP
E
G
Q
E
VVGG
F
D
L
S
A
L
I
E
R
-------
I
N
Y
A
I
Q
K
Y
R
A
R
R
V
S
I
D
S
V
T
S
V
-----
F
Q
Q
---
Y
D
A
S
S
V
V
R
R
E
L
F
R
L
V
A
R
L
K
Q
I
G
A
T
T
V
M
T
T
E
R
I
E
E
Y
G
P
I
A
R
Y
G
V
E
E
F
V
S
D
N
V
V
I
L
R
N
V
L
E
GE
R
R
R
R
T
L
E
I
L
K
L
R
G
T
S
H
M
K
G
E
Y
P
F
T
I
T
D
H
G
I
N
I
F
P
L
G
A
M
R
L
T
Q
R
S
S
N
V
R
V
S
SG
V
V
R
L
D
E
M
C
G
G
GFFKD
S
I
I
L
A
T
G
A
T
G
--
T
G
K
T
L
L
V
S
R
F
V
E
N
A
C
-
A
-
N
K
-
E
R
A
I
L
F
A
Y
E
-
E
----
S
----
R
A
Q
L
L
R
N
A
Y
S
W
GMD
F
E
E
M
E
---
R
Q
-
N
----------
L
L
K
--
I
-
V
-----
C
A
Y
P
E
S
A
G
L
E
D
H
L
Q
I
I
K
S
E
I
N
D
F
KPA
R
I
A
I
-
D
S
L
S
A
L
A
R
G
V
S
N
N
A
F
R
Q
F
V
I
G
V
T
G
Y
A
K
Q
E
E
I
T
G
L
F
T
N
T
S
D
Q
F
M
G
A
H
S
I
T
D
S
H
I
S
T
I
T
D
T
I
I
L
L
Q
Y
V
E
I
R
G
E
M
S
------
R
----
A
-
I
N
V
-
F
K
M
R
G
S
W
HDKAI
R
E
F
M
I
S
D
K
G
P
D
I
K
D
S
F
R
NFERIISG
S
P
T
R
I
38
HHSearch
35.86
22%
-27
- C1 -
-
1XHK
-
LONB_METJA
A:
[4-186]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
K
V
G
------
V
I
Y
G
L
A
V
L
G
AG
G
I
G
D
V
T
K
I
I
V
Q
I
L
E
S
K
N
-
P
G
T
H
L
L
N
I
S
G
D
I
A
K
----
H
----
S
I
T
L
A
S
A
L
---------
S
K
---
K
L
-
V
A
E
KKLPLPKK
D
I
D
--
L
-
N
-----
N
K
E
I
Y
I
Q
---------------------
F
S
Q
S
Y
S
K
I
D
G
D
S
A
T
A
A
V
C
L
A
I
I
S
A
L
L
D
I
P
L
K
Q
D
F
A
I
T
G
S
L
D
L
S
G
N
V
L
A
I
G
G
V
N
E
K
I
E
A
A
K
R
Y
G
F
K
R
V
I
I
P
E
A
N
M
I
D
V-----
I
----
E
-
T
E
G
-
I
E
I
I
P
V
K
-----
T
L
D
E
I
V
P
L
V
F
D
L
------------------
43
HHSearch
33.91
21%
-7
- C1 -
-
3LDA
-
RAD51_YEAST
A:
[156-396]
---------------------------------------------------------------------
E
L
I
C
L
T
T
G
S
K
N
L
D
T
L
L
G
G
G
V
E
T
G
S
I
T
E
L
F
G
E
F
R
T
G
K
S
Q
L
C
H
T
L
A
V
T
C
Q
I
PLDIGG
G
E
-
G
K
C
L
Y
I
D
T
E
G
T
FR
P
V
R
L
V
S
I
A
Q
R
F
G
L
D
P
D
D
A
L
N
N
V
A
----------------------
Y
A
R
A
Y
N
A
D
H
Q
L
R
L
L
D
A
A
A
Q
M
M
S
E
S
R
F
S
L
I
V
V
D
S
V
M
A
L
Y
R
------GE
L
S
A
R
Q
M
H
L
A
K
F
M
R
A
L
Q
R
L
A
D
Q
F
G
-
V
A
V
V
V
T
N
Q
V
---------
N
I
M
A
Y
S
S
T
T
R
L
G
F
K
K
G
K
G
---
C
Q
R
L
C
K
V
V
D
S
P
-
C
L
P
-
E
A
E
C
V
F
A
I
Y
E
D
G
V
G
D
P
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
HHSearch
32.85
22%
-29
- C1 -
-
1XHK
1
B:
[4-186]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
K
V
G
------
V
I
Y
G
L
A
V
L
G
AG
G
I
G
D
V
T
K
I
I
V
Q
I
L
E
S
K
N
-
P
G
T
H
L
L
N
I
S
G
D
I
A
K
----
H
----
S
I
T
L
A
S
A
L
---------
S
K
---
K
L
-
V
A
E
KKLPLPKK
D
I
D
--
L
-
N
-----
N
K
E
I
Y
I
Q
---------------------
F
S
Q
S
Y
S
K
I
D
G
D
S
A
T
A
A
V
C
L
A
I
I
S
A
L
L
D
I
P
L
K
Q
D
F
A
I
T
G
S
L
D
L
S
G
N
V
L
A
I
G
G
V
N
E
K
I
E
A
A
K
R
Y
G
F
K
R
V
I
I
P
E
A
N
M
I
D
V-----
I
----
E
-
T
E
G
-
I
E
I
I
P
V
K
-----
T
L
D
E
I
V
P
L
V
F
D
L
------------------
18
PsiBlast_PDB
31.33
21%
-94
- C1 -
-
1U9I
1
KAIC_SYNE7
A:
[258-398]
--------------------------------------------------------------------
S
S
N
V
R
V
S
S
G
V
V
R
L
D
E
M
C
G
G
G
F
F
K
D
S
I
I
L
A
T
G
A
T
G
T
G
K
T
L
L
V
S
R
F
V
E
N
A
C
A
------
N
K
-
E
R
A
I
L
F
A
Y
E
E
S
--
R
A
Q
L
L
R
N
A
Y
S
W
G
M
D
----
F
E
E
M
E
------------------------
R
Q
N
L
L
K
I
-------
V
C
A
Y
P
E
S
----
A
G
L
E
D
H
L
Q
I
I
K
S
E
I
N
D
F
K
---
P
A
R
I
A
I
--
D
S
L
S
A
L
A
R
G
V
S
N
N
A
-
F
R
Q
F
V
I
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
HHSearch
31.07
21%
-36
- C1 -
-
3WU4
-
?
E:
[9-192]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
R
V
G
------
Q
V
T
G
L
A
W
T
E
--
V
G
G
D
L
L
T
I
E
T
A
C
V
P
G
-
K
----
G
K
L
T
Y
T
G
S
L
-
G
----
E
VMQE
S
I
Q
A
A
L
T
V
---------
V
R
ARA
E
K
-
L
----------
G
I
N
PD
F
Y
E
-----
K
R
D
I
H
V
H
---------------------
V
P
E
G
A
T
P
K
D
G
P
A
A
G
I
A
M
C
T
A
L
V
S
C
L
T
G
N
P
V
R
A
D
V
A
M
T
G
E
I
T
L
R
G
Q
V
L
P
I
G
G
L
K
E
K
L
L
A
A
H
R
G
G
I
K
T
V
L
I
P
F
E
N
K
R
D
LE----
E
IPDN
V
-
I
A
D
-
L
D
I
H
P
V
K
-----
R
I
E
E
V
L
T
L
A
L
Q
N
E
P
S
---------------
30
HHSearch
31.02
19%
-16
- C1 -
-
5E7S
-
?
G:
[592-774]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
Q
V
G
------
T
A
Q
G
L
A
W
T
P
--
V
G
G
T
L
L
T
I
E
V
A
A
V
P
G
-
S
----
G
K
L
S
L
T
G
Q
L
-
G
EVMK
E
----
S
A
Q
A
A
L
T
Y
---------
L
R
---
A
H
T
Q
----------
D
Y
G
--
L
-
P
EDFYN
K
V
D
L
H
V
H
---------------------
V
P
D
G
A
T
P
K
D
G
P
S
A
G
I
T
M
A
T
A
I
A
S
A
L
S
R
R
P
A
R
M
D
I
A
M
T
G
E
V
S
L
R
G
K
V
M
P
I
G
G
V
K
E
K
L
L
A
A
H
Q
A
G
I
H
K
I
V
L
P
K
D
N
E
A
Q
LEELPK
E
----
V
-
L
E
G
-
L
E
I
K
L
V
E
-----
D
V
G
E
V
L
E
Y
L
L
L
P
E
P
----------------
35
HHSearch
30.24
21%
-34
- C1 -
-
3WU6
-
?
E:
[9-192]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
R
V
G
------
Q
V
T
G
L
A
W
T
E
--
V
G
G
D
L
L
T
I
E
T
A
C
V
P
G
-
K
----
G
K
L
T
Y
T
G
S
L
-
G
----
E
VMQE
S
I
Q
A
A
L
T
V
---------
V
R
ARA
E
K
-
L
----------
G
I
N
PD
F
Y
E
-----
K
R
D
I
H
V
H
---------------------
V
P
E
G
A
T
P
K
D
G
P
A
A
G
I
A
M
C
T
A
L
V
S
C
L
T
G
N
P
V
R
A
D
V
A
M
T
G
E
I
T
L
R
G
Q
V
L
P
I
G
G
L
K
E
K
L
L
A
A
H
R
G
G
I
K
T
V
L
I
P
F
E
N
K
R
D
LE----
E
IPDN
V
-
I
A
D
-
L
D
I
H
P
V
K
-----
R
I
E
E
V
L
T
L
A
L
Q
N
E
P
S
---------------