@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VTH2: (2017-12-13 )
MIVMNINVVKVRLARELLLVHLVANDVIRLSTVGQRMTEQKNSSKTTALAQALLLEQVEFFKKQLSIENSPIYFRQFIQLFMQHADEIKLYEVVDLEQLQAVVKRYAFEMQLGAGLLEFIGEIAQRIYLSAMKSPVQLQDLVSDHQFEMWLSKFLEMEHIPHYLNQFLRTSPSVQQLCQYIATSTLEQKLPKFLTASRVDDYHFEWQHKLKKFSFLQQQRLEHKLETWIASFIHEQLTELSLLSAEDLESLVRHIWEDIRHKKIYEFMKQLTPLDVEEFFVLIYEYWKELRQSQFMQGLILYGVEVFYDFYKDQSLFEVLSAIGLSETDLQTEALRFYPKVMDAFNEHGILEPLLQALLAPFYQSSKTLDIIEKHLSE
Atome Classification :
(20 SA)
----------------------------------------------------------------.........10........20......--.--.30........40........50..-......60..---------------------------------...----...70........-80........90.....--------...100.......110------------.----------------------------------.......120---....---------.-..130......-.140.--------.-.....--150---.......-.160.-..----------------...---.170....-..-----.-------180....------------...190.......200-.......210.......--------220----.---------......230.-----------.--------.....240.----------------.-....----.250.......260.....-..270-...---....280.--------------.--------.....290-----------....-----..----.---300.......310.---------......320.......330---........340.......350........360.--......370..---......----------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
----------------------------------------------------------------
M
I
V
M
N
I
N
V
V
K
V
R
L
A
R
E
L
L
L
V
H
L
V
ANDV--
I
--
R
L
S
T
V
G
Q
R
M
T
E
QKNS
S
K
T
T
A
L
A
Q
A
L
-
L
L
E
Q
V
E
F
F
K
K
---------------------------------
Q
LS----IENS
P
I
Y
F
R
Q
F
I
Q
-
L
F
M
QHADE
I
K
L
Y
E
V
V
D
L
--------
E
Q
L
Q
A
V
V
K
R
Y
A
F
E
M
Q
-------------L----------------------------------
G
A
G
L
L
E
F
I
G
E
---
I
A
Q
R
---------
I
-
Y
L
S
A
MKS
P
V
Q
L
-
Q
D
L
V
S
--------
D
-
H
Q
F
E
M
--
W
L
----
S
K
F
L
E
M
E
-
H
I
P
H
Y
-
L
N
----------------
Q
F
L
---RTSP
S
V
Q
Q
-
L
C
-----
Q
-------
Y
I
A
T
S
T
L
------------
E
Q
K
L
P
K
F
L
T
A
S
RVDDY-
H
F
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W
Q
H
K
L
K
K
F
S
F
L
Q
Q
Q
--------
R
L
E
----
H
---------
K
L
E
T
W
I
A
S
F
I
-----------
H
--------
E
Q
L
T
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L
SLL----------------
S
-
A
E
D
L
----
E
S
L
V
R
H
I
W
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D
I
R
H
K
K
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Y
E
F
-
M
K
QLT-PL
D
---
V
E
E
F
F
V
L
I
--------------
Y
--------
E
Y
W
K
E
L
R
Q
-----------
S
Q
F
M
-----
Q
G
----
L
---
I
L
Y
G
V
E
V
F
Y
D
F
YK
D
---------
Q
S
L
F
E
V
L
S
AIGLSETD
L
Q
----
T
E
A
L
R
F
Y
P
K
V
M
D
A
F
N
EHG
I
-
L
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P
L
L
Q
A
L
L
A
P
F
Y
--QSS
K
T
L
D
--
I
I
---
E
K
H
LSE----------
37
Fugue
56.55
17%
-40
- C1 -
-
4WID
1
?
A:
[10-362]
----------------------------------------------------------------------
K
D
M
A
L
Q
H
A
V
D
L
L
E
K
M
L
A
D
E
E
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--
L
--
T
E
F
N
L
G
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P
L
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N
D
D
P
I
K
---------
T
L
E
E
I
I
Q
E
---------------------------------
G
D
D
----
V
V
G
A
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Q
L
V
V
T
Q
I
K
-
L
R
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R
--
N
R
R
L
A
D
E
I
I
R
--------
E
Q
L
T
D
I
R
K
V
F
S
D
K
------------------------------------------------------
F
E
K
L
E
Q
---
G
I
Q
N
---------
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-
Y
L
L
L
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K
L
K
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P
F
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Q
D
M
----------
R
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A
N
----
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Q
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N
D
T
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--
V
P
P
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-
Y
K
----------------
E
F
------
M
V
C
L
K
Q
-
I
V
-----
Q
-------
Y
A
V
N
S
S
S
------------
L
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K
F
V
M
L
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--
K
K
D
D
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-
K
D
R
V
T
Y
T
C
M
K
Y
L
L
M
A
M
Q
G
TGGPKAI
N
N
E
----
E
---------
H
A
K
L
F
F
Q
L
S
N
-----------
Y
--------
D
D
L
T
D
A
N
H
D
----------------
G
-
L
E
L
I
----
K
K
L
D
K
E
-------
Q
K
E
V
A
F
-
H
V
N
N
F
-
T
H
L
---
V
T
T
L
G
M
A
L
--------------
Y
--------
K
E
G
H
Q
K
N
D
-----------
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A
M
L
G
M
H
T
P
I
T
----
M
---
L
S
D
Q
V
R
V
L
I
L
Y
L
I
D
---------
E
I
V
H
A
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H
T
N
S
N
Q
S
N
D
E
L
I
----
D
G
L
K
P
K
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R
I
V
I
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F
H
A
T
L
M
-
M
G
I
D
K
M
----
K
F
Y
--
S
L
N
E
L
R
E
--
I
V
---
N
D
K
I
------------
34
Fugue
53.22
19%
-0
* C6 *
-
5UAO
1
?
A:
[21-539]
-----------------------------------------------PADDDPGAIR
T
V
G
V
I
G
G
G
T
A
G
Y
L
T
A
L
A
L
K
A
K
R
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L
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V
A
L
V
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S
A
D
--
I
--
P
I
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G
V
G
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A
T
V
----
S
Y
M
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M
F
L
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L
-
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P
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W
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A
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FDWGTGSVG
L
V
G
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----
L
R
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T
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N
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N
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Q
-
A
M
L
M
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D
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R
G
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G
G
--------
H
V
S
L
M
K
Y
L
P
F
A
Y
H
M
D
------------------------------------------------
N
A
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L
V
R
Y
L
T
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---
L
A
A
R
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V
R
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V
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A
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V
-
A
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L
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G
G
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TD
G
R
R
L
H
Y
D
-
F
Y
V
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C
TG
F
R
----
S
L
L
L
E
K
A
L
G
I
P
F
E
S
Y
A
----------------
S
S
L
---
F
T
D
A
A
V
T
G
-
T
L
-----
A
HGGHLKP
Y
T
T
A
T
T
M
NA
G
W
C
W
T
I
P
T
PE
S
D
H
L
G
Y
V
F
S
S
A
A
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D
P
D
-
D
A
A
A
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M
A
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R
F
P
G
V
T
R
E
A
--------
L
V
R
F
R
S
G
R
---------
H
R
E
A
W
R
G
N
V
M
-----------
A
V
G
NSYAFV
E
P
L
E
S
S
G
L
L
----------------
M
I
A
T
A
V
----
Q
I
L
V
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L
L
P
S
S
R
R
D
P
L
P
S
D
A
-
A
N
Q
A
L
-
A
H
R
W
D
A
I
R
W
F
L
S
I
H
--------------
Y
R
F
NGRLDT
P
F
W
K
E
A
R
A
ETDISGI
E
P
L
L
R
L
F
A
-----
A
G
----
A
---
P
L
T
G
R
D
S
F
T
R
Y
L
A
D
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A
APLFYG
L
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V
D
T
L
L
L
G
Q
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A
R
L
L
P
PREP
P
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Q
W
R
A
R
A
A
A
A
R
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G
L
R
Q
S
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A
L
D
A
Y
A
A
D
P
C
--
L
N
A
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L
L
S
--
D
S
---
D
S
W
A
G
E
R
V
A
V
R
A
G---
38
Fugue
50.29
17%
1
- C6 -
-
5GHR
-
?
A:
[2-464]
------------------------------------------------------------------
D
K
E
A
F
L
E
R
V
R
E
G
A
E
L
I
K
M
H
I
E
L
G
H
T
--
I
--
R
L
I
S
---------
H
R
D
A
D
G
I
T
A
G
A
I
-
L
A
K
A
V
A
R
E
G
G
---------------------------------
T
F
Q
----
L
S
I
V
K
Q
V
S
E
E
L
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-
Q
L
A
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K
R
E
I
Y
V
F
S
D
L
G
S
--------
G
S
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K
L
N
F
A
T
V
-------------
V
V
A
D
HHPPEKDSFSTDSHVLVNPVPFGANSVRDLS
G
S
G
V
A
Y
F
V
A
R
E
M
N
R
K
N
R
---------
D
M
A
Y
V
A
I
V
G
A
V
G
D
M
Q
E
I
D
G
--------
T
F
H
G
L
N
L
--
E
I
----
I
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D
G
K
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L
-
G
I
L
E
V
-
R
K
----------------
E
L
R
LFG
R
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S
R
P
L
Y
Q
M
L
A
Y
ATN
P
E
-------
I
P
E
I
T
G
D
------------
E
R
K
A
I
E
W
L
R
A
K
G
F
D
P
E
M
K
Y
-
W
Q
L
R
E
E
E
K
R
K
L
H
E
A
--------
L
L
V
----
H
M
I
K
H
GAP
K
E
A
I
D
R
L
I
G
D
V
V
I
S
PLYPEGDVR
H
--------
E
A
R
E
F
A
T
L
L
----------------
N
-
A
T
G
R
L
NA
G
T
L
G
V
A
I
C
L
G
D
E
E
A
Y
K
V
A
R
K
M
L
D
D
Y
K
-
K
E
Q
---
I
E
A
R
K
F
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I
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N
WNM
V
E
E
G
EH
A
Y
V
F
--------
Y
A
G
K
N
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R
D
-----------
T
L
V
G
-----
I
A
----
A
N
M
A
I
N
A
P
V
V
V
L
A
D
S
D
E
D
---------
E
N
L
V
K
G
S
A
R
T
T
E
K
A
L
E
K
G
----
Y
H
L
G
E
A
L
K
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V
A
E
K
L
G
G
E
G
G
-
G
H
A
I
A
A
G
I
R
F
P
K
N
--
R
I
D
E
F
I
K
--
L
F
---
N
E
A
L
------------
40
Fugue
49.84
14%
-0
- C2 -
-
5H11
-
?
A:
[1-509]
GPLGSQ
L
I
Q
E
F
T
A
A
Q
R
RGEIG
R
M
R
E
V
A
A
V
L
L
H
F
KG
Y
A
H
C
V
D
V
Y
I
K
Q
C
Q
E
G
A
YMRND
V
F
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D
I
A
I
L
C
Q
R
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N
K
Q
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G
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V
F
C
S
P
E
T
V
M
A
K
L
I
Q
S
I
F
E
N
K
--
I
Q
A
H
V
K
E
R
L
D
E
T
R
N
S
D
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E
Q
Y
L
K
N
L
Y
D
L
Y
T
R
T
T
A
L
A
A
---------------------------------
K
L
T
D
YNL
G
S
D
K
H
T
F
L
S
K
L
I
K
N
I
F
S
C
Y
L
E
S
Y
I
D
M
E
R
Q
Y
L
--------
Q
N
R
S
G
M
I
L
Q
R
Y
Y
D
S
K
NHQKRIDTHGETL
L
----------------------------------
S
Q
E
V
V
V
N
L
L
Q
---
E
T
R
H
---------
A
-
F
E
R
C
N
K
L
S
D
P
A
-
D
L
P
K
N
--------
A
-
F
S
I
F
L
--
I
L
----
V
E
Y
L
C
V
D
-
H
I
D
Y
A
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L
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L
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A
IPSADAKNANL
Y
F
L
---
D
V
V
Q
Q
A
N
T
-
I
F
-----
H
-------
L
F
D
K
Q
F
N
------------
D
H
L
M
P
L
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S
S
P
K
L
T
E
C
-
L
H
K
K
K
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V
I
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Q
M
E
V
K
L
D
T
--------
G
I
D
----
R
---------
T
L
N
C
M
I
G
Q
M
K
-----------
Y
--------
I
L
T
T
E
Q
K
K
T
DFKPEDEN
N
V
M
I
Q
YT
T
A
-
C
S
K
V
----
C
A
Y
V
G
K
Q
V
E
R
V
R
R
S
M
D
G
K
N
-
V
D
T
V
L
-
T
E
L
---
G
V
R
F
H
R
L
I
--------------
H
--------
E
H
L
Q
Q
F
S
Y
-----------
S
S
M
G
-----
G
M
----
L
---
A
I
C
D
V
A
E
Y
R
R
S
A
K
D
---------
F
R
V
P
L
V
L
Q
L
--
F
D
T
L
H
A
L
----
C
N
L
L
V
V
A
P
D
N
L
K
Q
V
C
S
G
E
Q
-
L
T
N
L
D
R
N
L
L
H
A
F
V
--
Q
L
R
V
D
Y
R
SA
R
L
---
G
R
H
F
S
-----------
35
Fugue
44.73
14%
-62
- C4 -
-
5ULM
-
M3K5_HUMAN
A:
[7-390]
------------------------------------------------------------------
F
R
E
S
I
L
N
D
I
R
K
A
R
N
L
Y
T
G
K
E
L
A
A
E
L
--
A
--
R
I
R
---
Q
R
V
D
N
I
E
V
L
T
A
D
I
V
I
N
L
L
L
-
S
Y
R
D
I
------------------------------------------------------
Q
D
Y
D
-
S
I
V
K
L
V
E
T
L
E
K
L
P
T
F
D
L
--------
A
S
H
H
H
V
K
F
H
Y
A
F
A
L
N
-------------
R
----------------------------------
R
-
N
L
P
G
D
R
A
K
---
A
L
D
I
---------
M
-
I
P
M
V
Q
Q
V
A
S
D
M
-
Y
C
L
V
G
--------
R
-
I
Y
K
D
M
--
F
L
D
S
NF
T
D
T
E
S
R
D
-
H
G
A
S
W
-
F
K
----------------
K
A
F
---
E
S
E
P
T
L
Q
S
-
G
I
-----
N
-------
Y
A
V
L
L
L
A
------------
A
G
H
-----
S
S
F
E
L
R
K
V
-
G
V
K
L
S
S
L
L
G
K
K
G
N
L
E
K
L
--------
Q
S
Y
----
W
---------
E
V
G
F
F
L
G
A
S
V
-----------
L
--------
A
N
D
H
M
R
V
I
Q
----------------
A
-
S
E
K
L
----
F
K
L
K
T
P
A
W
Y
L
K
S
I
V
E
T
I
L
I
-
Y
K
H
F
V
K
P
V
A
---
K
Q
E
L
V
D
F
W
--------------
M
--------
D
F
L
V
E
A
T
K
-----------
T
D
V
T
-----
V
V
RFP
V
L
---
I
L
E
P
T
K
I
Y
Q
P
S
Y
L
S
---------
I
N
N
E
V
E
E
K
T
I
S
I
W
H
V
-
L
P
----
D
D
K
K
G
I
H
E
W
N
F
S
A
S
S
V
R
G
V
-
S
I
S
K
F
E
E
R
C
C
F
L
Y
V
L
H
N
S
D
D
F
Q
--
I
Y
FCT
E
L
H
C
K
K
F
F
E
M
V
N
T
I
T
E
18
PsiBlast_PDB
40.60
24%
-6
- C5 -
-
2F7M
-
FPPS_HUMAN
F:
[97-218]
-------------------------------------------------------------------------------------
L
V
A
D
D
I
--
M
DS
S
L
T
R
R
G
Q
I
C
W
Y
Q
K
P
G
V
G
L
D
A
I
N
D
A
N
-
L
L
E
A
C
I
Y
R
L
L
---------------------------------
K
L
Y
----
C
R
E
Q
P
-
Y
Y
L
N
L
I
E
-
L
F
L
Q
S
S
Y
Q
T
E
I
G
Q
T
L
D
L
LTAPQGNV
D
L
V
R
F
T
E
K
R
Y
K
S
I
V
K
-------------
Y
----------------------------------
K
T
A
F
Y
S
F
Y
L
P
---
I
A
A
A
---------
M
-
Y
M
A
G
I
D
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
40.58
10%
-160
- C5 -
-
5L85
-
A:
[17-65]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
S
A
T
L
-
R
S
L
L
L
--------
N
-
P
H
L
R
Q
--
L
M
----
V
N
L
D
Q
G
E
-
D
-
K
A
K
-
L
M
----------------
R
A
Y
---
M
Q
E
P
L
F
V
E
-
F
A
-----
D
-------
C
C
L
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
40.55
24%
-4
- C5 -
-
4GA3
1
FPPS_HUMAN
A:
[95-216]
-------------------------------------------------------------------------------------
L
V
A
D
D
I
--
M
D
S
S
L
T
R
R
G
Q
I
C
W
Y
Q
K
P
G
V
G
L
D
A
I
N
D
A
N
-
L
L
E
A
C
I
Y
R
L
L
---------------------------------
K
L
Y
----
C
R
E
Q
P
-
Y
Y
L
N
L
I
E
-
L
F
L
Q
S
S
Y
Q
T
E
I
G
Q
T
L
D
L
L
T
A
PQGNV
D
L
V
R
F
T
E
K
R
Y
K
S
I
V
K
-------------
Y
----------------------------------
K
T
A
F
Y
S
F
Y
L
P
---
I
A
A
A
---------
M
-
Y
M
A
G
I
D
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
40.44
24%
-37
- C5 -
-
4P0X
1
FPPS_HUMAN
A:
[95-217]
-------------------------------------------------------------------------------------
L
V
A
D
D
I
--
M
D
S
S
L
T
R
R
G
Q
I
C
W
Y
Q
K
P
G
V
G
L
D
A
I
N
D
A
N
-
L
L
E
A
C
I
Y
R
L
L
---------------------------------
K
L
Y
----
C
R
E
Q
P
-
Y
Y
L
N
L
I
E
-
L
F
L
Q
S
S
Y
Q
T
E
I
G
Q
T
L
D
L
L
T
APQ---
D
L
V
R
F
T
E
K
R
Y
K
S
I
V
K
-------------
Y
----------------------------------
K
T
A
F
Y
S
F
Y
L
P
---
I
A
A
A
---------
M
-
Y
M
A
G
I
D
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
38.96
24%
-8
- C5 -
-
4P0W
2
FPPS_HUMAN
A:
[95-216]
-------------------------------------------------------------------------------------
L
V
A
D
D
I
--
M
D
S
S
L
T
R
R
G
Q
I
C
W
Y
Q
K
P
G
V
G
L
D
A
I
N
D
A
N
-
L
L
E
A
C
I
Y
R
L
L
---------------------------------
K
L
Y
----
C
R
E
Q
P
-
Y
Y
L
N
L
I
E
-
L
F
L
Q
S
S
Y
Q
T
E
I
G
Q
T
L
D
L
L
T
A
PQGNV
D
L
V
R
F
T
E
K
R
Y
K
S
I
V
K
-------------
Y
----------------------------------
K
T
A
F
Y
S
F
Y
L
P
---
I
A
A
A
---------
M
-
Y
M
A
G
I
D
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
38.94
24%
-6
- C5 -
-
2QIS
1
FPPS_HUMAN
A:
[121-242]
-------------------------------------------------------------------------------------
L
V
A
D
D
I
--
M
D
S
S
L
T
R
R
G
Q
I
C
W
Y
Q
K
P
G
V
G
L
D
A
I
N
D
A
N
-
L
L
E
A
C
I
Y
R
L
L
---------------------------------
K
L
Y
----
C
R
E
Q
P
-
Y
Y
L
N
L
I
E
-
L
F
L
Q
S
S
Y
Q
T
E
I
G
Q
T
L
D
L
L
T
A
PQGNV
D
L
V
R
F
T
E
K
R
Y
K
S
I
V
K
-------------
Y
----------------------------------
K
S
A
F
Y
S
F
Y
L
P
---
I
A
A
A
---------
M
-
Y
M
A
G
I
D
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
38.84
24%
-2
- C5 -
-
3RYE
1
FPPS_HUMAN
A:
[96-217]
-------------------------------------------------------------------------------------
L
V
A
D
D
I
--
M
D
S
S
L
T
R
R
G
Q
I
C
W
Y
Q
K
P
G
V
G
L
D
A
I
N
D
A
N
-
L
L
E
A
C
I
Y
R
L
L
---------------------------------
K
L
Y
----
C
R
E
Q
P
-
Y
Y
L
N
L
I
E
-
L
F
L
Q
S
S
Y
Q
T
E
I
G
Q
T
L
D
L
L
T
A
PQGNV
D
L
V
R
F
T
E
K
R
Y
K
S
I
V
K
-------------
Y
----------------------------------
K
T
A
F
Y
S
F
Y
L
P
---
I
A
A
A
---------
M
-
Y
M
A
G
I
D
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
38.74
24%
-1
- C5 -
-
2F89
1
FPPS_HUMAN
F:
[97-218]
-------------------------------------------------------------------------------------
L
V
A
D
D
I
--
M
DS
S
L
T
R
R
G
Q
I
C
W
Y
Q
K
P
G
V
G
L
D
A
I
N
D
A
N
-
L
L
E
A
C
I
Y
R
L
L
---------------------------------
K
L
Y
----
C
R
E
Q
P
-
Y
Y
L
N
L
I
E
-
L
F
L
Q
S
S
Y
Q
T
E
I
G
Q
T
L
D
L
LTAPQGNV
D
L
V
R
F
T
E
K
R
Y
K
S
I
V
K
-------------
Y
----------------------------------
K
T
A
F
Y
S
F
Y
L
P
---
I
A
A
A
---------
M
-
Y
M
A
G
I
D
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
38.54
24%
-4
- C5 -
-
3S4J
1
FPPS_HUMAN
A:
[96-217]
-------------------------------------------------------------------------------------
L
V
A
D
D
I
--
M
D
S
S
L
T
R
R
G
Q
I
C
W
Y
Q
K
P
G
V
G
L
D
A
I
N
D
A
N
-
L
L
E
A
C
I
Y
R
L
L
---------------------------------
K
L
Y
----
C
R
E
Q
P
-
Y
Y
L
N
L
I
E
-
L
F
L
Q
S
S
Y
Q
T
E
I
G
Q
T
L
D
L
L
T
A
PQGNV
D
L
V
R
F
T
E
K
R
Y
K
S
I
V
K
-------------
Y
----------------------------------
K
T
A
F
Y
S
F
Y
L
P
---
I
A
A
A
---------
M
-
Y
M
A
G
I
D
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
38.41
25%
1
- C5 -
-
4Q23
1
FPPS_HUMAN
A:
[122-243]
-------------------------------------------------------------------------------------
L
V
A
D
D
I
--
M
D
S
S
L
T
R
R
G
Q
I
C
W
Y
Q
K
P
G
V
G
L
D
A
I
N
D
A
N
-
L
L
E
A
C
I
Y
R
L
L
---------------------------------
K
L
Y
----
C
R
E
Q
P
-
Y
Y
L
N
L
I
E
-
L
F
L
Q
S
S
Y
Q
T
E
I
G
Q
T
L
D
L
L
T
A
PQGNV
D
L
V
R
F
T
E
K
R
Y
K
S
I
V
K
-------------
Y
----------------------------------
K
A
A
F
Y
S
F
Y
L
P
---
I
A
A
A
---------
M
-
Y
M
A
G
I
D
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
38.30
24%
1
- C5 -
-
5CG5
1
FPPS_HUMAN
A:
[94-215]
-------------------------------------------------------------------------------------
L
V
A
D
D
I
--
M
D
S
S
L
T
R
R
G
Q
I
C
W
Y
Q
K
P
G
V
G
L
D
A
I
N
D
A
N
-
L
L
E
A
C
I
Y
R
L
L
---------------------------------
K
L
Y
----
C
R
E
Q
P
-
Y
Y
L
N
L
I
E
-
L
F
L
Q
S
S
Y
Q
T
E
I
G
Q
T
L
D
L
L
T
A
PQGNV
D
L
V
R
F
T
E
K
R
Y
K
S
I
V
K
-------------
Y
----------------------------------
K
T
A
F
Y
S
F
Y
L
P
---
I
A
A
A
---------
M
-
Y
M
A
G
I
D
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
38.29
24%
-5
- C5 -
-
5CG6
2
FPPS_HUMAN
A:
[94-215]
-------------------------------------------------------------------------------------
L
V
A
D
D
I
--
M
D
S
S
L
T
R
R
G
Q
I
C
W
Y
Q
K
P
G
V
G
L
D
A
I
N
D
A
N
-
L
L
E
A
C
I
Y
R
L
L
---------------------------------
K
L
Y
----
C
R
E
Q
P
-
Y
Y
L
N
L
I
E
-
L
F
L
Q
S
S
Y
Q
T
E
I
G
Q
T
L
D
L
L
T
A
PQGNV
D
L
V
R
F
T
E
K
R
Y
K
S
I
V
K
-------------
Y
----------------------------------
K
T
A
F
Y
S
F
Y
L
P
---
I
A
A
A
---------
M
-
Y
M
A
G
I
D
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
37.66
25%
-2
- C5 -
-
4N9U
3
FPPS_HUMAN
A:
[122-243]
-------------------------------------------------------------------------------------
L
V
A
D
D
I
--
M
D
S
S
L
T
R
R
G
Q
I
C
W
Y
Q
K
P
G
V
G
L
D
A
I
N
D
A
N
-
L
L
E
A
C
I
Y
R
L
L
---------------------------------
K
L
Y
----
C
R
E
Q
P
-
Y
Y
L
N
L
I
E
-
L
F
L
Q
S
S
Y
Q
T
E
I
G
Q
T
L
D
L
L
T
A
PQGNV
D
L
V
R
F
T
E
K
R
Y
K
S
I
V
K
-------------
Y
----------------------------------
G
T
A
F
Y
S
F
Y
L
P
---
I
A
A
A
---------
M
-
Y
M
A
G
I
D
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
37.43
24%
-7
- C5 -
-
4KPD
2
FPPS_HUMAN
A:
[122-243]
-------------------------------------------------------------------------------------
L
V
A
D
D
I
--
M
D
S
S
L
T
R
R
G
Q
I
C
W
Y
Q
K
P
G
V
G
L
D
A
I
N
D
A
N
-
L
L
E
A
C
I
Y
R
L
L
---------------------------------
K
L
Y
----
C
R
E
Q
P
-
Y
Y
L
N
L
I
E
-
L
F
L
Q
S
S
Y
Q
T
E
I
G
Q
T
L
D
L
L
T
A
PQGNV
D
L
V
R
F
T
E
K
R
Y
K
S
I
V
K
-------------
Y
----------------------------------
K
T
A
F
F
S
F
Y
L
P
---
I
A
A
A
---------
M
-
Y
M
A
G
I
D
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
36.90
25%
6
- C5 -
-
3CP6
1
FPPS_HUMAN
A:
[123-244]
-------------------------------------------------------------------------------------
L
V
A
D
D
I
--
M
D
S
S
L
T
R
R
G
Q
I
C
W
Y
Q
K
P
G
V
G
L
D
A
I
N
D
A
N
-
L
L
E
A
C
I
Y
R
L
L
---------------------------------
K
L
Y
----
C
R
E
Q
P
-
Y
Y
L
N
L
I
E
-
L
F
L
Q
S
S
Y
Q
T
E
I
G
Q
T
L
D
L
L
T
A
PQGNV
D
L
V
R
F
T
E
K
R
Y
K
S
I
V
K
-------------
Y
----------------------------------
K
A
A
F
Y
S
F
Y
L
P
---
I
A
A
A
---------
M
-
Y
M
A
G
I
D
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------