@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VTH3: (2017-12-13 )
MASHYEMFPAVVTRVEQLTPLIKRFTFKRQDGQNFPRFSGGSHIIVKMNEQLSNAYSLMSCTQDLSTYQVCVRKDVEGKGGSVFMHDQCNEGCEIQISEPKNLFPLAETGNKHILIAGGIGITPFLPQMDELAARGAEYELHYAYRSPEHAALLDELTQKHAGHIFSYVDSEGSMLNLDELISSQPKGTHVYVCGPKPMIDAVIDCCNKHRYRDEYIHWEQFASTVPEDGEAFTVVLAKSNQEIEVQSNQTILQAIETLNIDVACLCREGVCGTCETAILEGEAEHFDQYLSDAEKASQKSMMICVSRAKGKKLVLDL
Atome Classification :
(20 SA)
.........10........20--.........30........40.......-.-----50-------------------------------.........60........70...---------.---------------..----..80------.-.......90...-.....100....-...-110...-.....120.......130...---.--...140-.........150.-----......------160-.--------.---..----..-----------...---170-----.---------.---------...------..---.---180.----..--------..---------------..-190.......200......-.210.......220......-.230--........240.......250.......260.......270.......280.......290.......300.......310......
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MA
S
H
Y
E
M
F
P
A
V
V
T
R
V
E
Q
L
T
P
---
L
I
K
R
F
T
F
KRQDGQNFPRFSGG
S
H
I
I
V
K
M
-
N
-----
E
--------------------------------
Q
L
S
N
A
Y
S
L
M
S
C
T
Q
D
L
S
T
Y
Q
V
C
V
RK---------D---------------VE----GKGG------
S
-
V
F
M
HDQCNEG
C
E
-
I
Q
ISEPKN
L
F
PL-AET-G-N
K
H
I
-
L
I
AGGIGITPFLP
Q
M
D
E
L
A
AR---G--A
E
Y
E
---
L
H
Y
A
YRSP
E
H
A
A
L
-----
L
D
E
L
T
Q
------
K
---H--------A---
G
H
----
I
F
-----------
S
Y
V---DS------E---------G---------
S
M
L------
N
L
---
D
---
E
L
IS----SQ--------PK---------------G
T
-
H
V
Y
V
CGP
K
P
M
I
D
A
V
I
D
C
C
N
-KHRYRDEYI
H
W
E
Q
F
A
S
TVPE-DG-
E
--
A
F
T
V
V
L
AKSN
Q
E
I
E
VQS
N
Q
T
I
L
Q
A
I
E
TLN
I
D
V
A
C
L
CREGVCGT
C
E
T
A
ILEG
E
A
E
H
F
D
Q
Y
L
S
D
A
E
K
A
SQK
S
M
M
I
C
V
SRAKG
K
K
L
V
LDL
1
PsiBlast_PDB
79.02
35%
-21
- C2 -
-
2PIA
2
PDR_BURCE
A:
[17-321]
---------------
E
K
I
A
R
---
D
I
W
S
F
E
L
T
D
P
Q
G
A
P
L
P
P
F
E
A
G
A
N
L
T
V
A
V
-
P
-----
N
--------------------------------
G
S
R
R
T
Y
S
L
C
N
D
S
Q
E
R
N
R
Y
V
I
A
V
K
R
---------
D
---------------
S
N
----
G
R
G
G
------
S
-
I
S
F
I
D
D
T
S
E
G
D
A
-
V
E
V
S
L
P
R
N
E
F
P
L
-
D
K
R
-
A
-
K
S
F
I
-
L
V
A
G
G
I
G
I
T
P
M
L
S
M
A
R
Q
L
R
A
E
---
G
L-
R
S
F
R
---
L
Y
Y
L
T
R
D
P
E
G
T
A
F
-----
F
D
E
L
T
S
------
D
---
E
--------
W
---
R
S
----
D
V
-----------
K
I
H
---
H
D
------
H
---------
G
---------
D
P
T
------
K
A
---
F
---
D
F
W
S
V
F
EK
S
K
--------
P
----------------
A
Q
-
H
V
Y
C
C
G
P
Q
A
L
M
D
T
V
R
D
M
T
G
-
H
--
W
P
S
G
T
V
H
F
E
S
F
G
A
T
N
T
N
-
A
R
-
E
N
T
P
F
T
V
R
L
S
R
S
G
T
S
F
E
I
P
A
N
R
S
I
L
E
V
L
R
D
A
N
V
R
V
P
S
S
C
E
S
G
T
C
G
S
C
K
T
A
L
C
S
G
E
A
D
H
R
D
M
V
L
R
D
D
E
K
G
T
Q
--
I
M
V
C
V
S
R
A
K
S
A
E
L
V
L
D
L
59
HHSearch
76.63
33%
10
- C2 -
-
2PIA
2
PDR_BURCE
A:
[6-321]
----
D
G
F
L
R
L
K
I
A
S
K
E
K
I
A
R
---
D
I
W
S
F
E
L
T
D
P
Q
G
A
P
L
P
P
F
E
A
G
A
N
L
T
V
A
V
-
P
-----
N
--------------------------------
G
S
R
R
T
Y
S
L
C
N
D
S
Q
E
R
N
R
Y
V
I
A
V
K
R
---------
D
---------------
S
N
-----
G
R
G
------
G
S
I
S
F
I
D
D
T
S
E
G
D
A
-
V
E
V
S
L
P
R
N
E
F
P
L
-
D
K
R
-
A
-
K
S
F
I
-
L
V
A
G
G
I
G
I
T
P
M
L
S
M
A
R
Q
L
R
A
E
G--
L
--
R
S
F
R
---
L
Y
Y
L
T
R
D
P
E
G
T
A
F
-----
F
D
E
L
T
S
------
D
---
E
WRS-----
D
---
V
K
----
I
H
-----------
H
D
H
---
G
D
------
P
---------
T
---------
K
A
F
------
D
F
---
W
---
S
V
F
E
----
K
S
--------
K
P
---------------
A
Q
-
H
V
Y
C
C
G
P
Q
A
L
M
D
T
V
R
D
M
T
G
---
H
W
P
S
G
T
V
H
F
E
S
F
G
A
T
N
T
N
A
R
E
N
T
--
P
F
T
V
R
L
S
R
S
G
T
S
F
E
I
P
A
N
R
S
I
L
E
V
L
R
D
A
N
V
R
V
P
S
S
C
E
S
G
T
C
G
S
C
K
T
A
L
C
S
G
E
A
D
H
R
D
M
V
L
R
D
D
E
K
-
G
T
-
Q
I
M
V
C
V
S
R
A
K
S
A
E
L
V
L
D
L
74
HHSearch
56.53
20%
-21
- C2 -
-
2R6H
1
?
C:
[7-290]
----
V
K
E
W
E
C
E
V
L
S
N
K
N
V
S
T
---
F
I
K
E
F
V
V
K
L
P
E
G
E
T
M
-
N
F
K
S
G
S
Y
A
Q
I
K
I
-
P
-----
K
Y
N
I
R
YAD
Y
D
I
Q
DRFR
G
D
W
D
K
M
DAWS
L
T
C
K
N
E
E
E
T
V
R
A
Y
S
M
A
N
Y
P
A
E
G
N
I
I
T
L
N
V
R
I
---------
A
TPPFDRAANKWK
A
G
I
K
P
-----
G
I
S
------
S
-
S
Y
I
F
-
S
L
K
P
G
D
K
-
V
M
M
S
G
P
Y
G
D
F
H
I
-
Q
D
T
-
D
-
A
E
M
L
-
Y
I
G
G
G
A
G
M
A
P
L
R
A
Q
I
L
H
L
F
R
T
LKT
G
--
R
K
V
S
---
Y
W
Y
G
A
R
S
K
N
E
I
F
Y
-----
E
E
D
F
R
E
------
I
---
E
R
E
F
-----
P
N--
F
K
----
F
H
-----------
I
A
L
---
S
D
------
P
---------
Q
PEDNWTGYV
G
F
I
------
H
Q
V
I
Y
D
---
N
Y
L
K
----
D
H
DA------
P
E
---------------
D
I
-
E
Y
Y
M
C
G
P
G
P
M
A
N
A
V
K
G
M
L
E
-
N
L
G
V
P
R
N
M
L
F
F
D
D
F
G
---------------------------------------------------------------------------------------------------
73
HHSearch
56.35
20%
-24
- C2 -
-
2R6H
1
?
A:
[7-290]
----
V
K
E
W
E
C
E
V
L
S
N
K
N
V
S
T
---
F
I
K
E
F
V
V
K
L
P
E
G
E
T
M
-
N
F
K
S
G
S
Y
A
Q
I
K
I
-
P
-----
K
Y
N
I
R
YAD
Y
D
I
Q
DRFR
G
D
W
D
K
M
DAWS
L
T
C
K
N
E
E
E
T
V
R
A
Y
S
M
A
N
Y
P
A
E
G
N
I
I
T
L
N
V
R
I
---------
A
TPPFDRAANKWKAGI
K
P
-----
G
I
S
------
S
-
S
Y
I
F
-
S
L
K
P
G
D
K
-
V
M
M
S
G
P
Y
G
D
F
H
I
-
Q
D
T
-
D
-
A
E
M
L
-
Y
I
G
G
G
A
G
M
A
P
L
R
A
Q
I
L
H
L
F
R
T
LKT
G
--
R
K
V
S
---
Y
W
Y
G
A
R
S
K
N
E
I
F
Y
-----
E
E
D
F
R
E
------
I
---
E
R
E
F
-----
P
N--
F
K
----
F
H
-----------
I
A
L
---
S
D
------
P
---------
Q
PEDNWTGYV
G
F
I
------
H
Q
V
I
Y
D
---
N
Y
L
K
----
D
H
DA------
P
E
---------------
D
I
-
E
Y
Y
M
C
G
P
G
P
M
A
N
A
V
K
G
M
L
E
-
N
L
G
V
P
R
N
M
L
F
F
D
D
F
G
---------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
55.95
24%
12
- C2 -
-
1GVH
1
HMP_ECOLI
A:
[156-391]
-------------
R
I
V
A
K
T
P
RSA
L
I
T
S
F
E
L
E
P
V
D
G
G
A
V
A
E
Y
R
P
G
Q
Y
L
G
V
W
L
-
K
P
EGFP
H
--------------------------------
Q
E
I
R
Q
Y
S
L
-
T
R
K
P
D
G
K
G
Y
R
I
A
V
K
R
---------
E
----------------
E
----
G
G
Q
V
------
S
-
N
W
L
H
N
H
A
N
V
G
D
V
-
V
K
L
V
A
P
A
G
D
F
F
M
-
A
V
A
-
D
-
D
T
P
V
T
L
I
S
A
G
V
G
Q
T
P
M
L
A
M
L
D
T
L
A
K
A
---
G
HT
A
Q
V
N
---
W
F
H
A
A
E
N
G
D
V
H
A
F
-----
A
D
E
V
K
E
L
G
Q
S
LP
R
---
F
--------
T
---
A
H
----
T
W
Y
RQPS
E
A
D
R
A
K
G
Q
F
---
D
S
------
E
---------
G
----------
L
M
------
D
L
---
S
---
K
L
E
G
----
A
F
--------
S
D
---------------
P
T
M
Q
F
Y
L
C
G
P
V
G
F
M
Q
F
T
A
K
Q
L
V
-
D
L
G
V
K
Q
E
N
I
H
Y
E
C
F
G
---------------------------------------------------------------------------------------------------
66
HHSearch
54.01
19%
-84
- C2 -
-
1QFJ
1
FRE_ECOLI
D:
[2-231]
------
T
L
S
C
K
V
T
S
V
E
A
I
T
D
---
T
V
Y
R
V
R
I
V
P
D
A
--
A
F
-
S
F
R
A
G
Q
Y
L
M
V
V
M
-
D
-----
E
--------------------------------
R
D
K
R
P
F
S
M
A
S
T
P
D
E
K
G
F
I
E
L
H
I
G
-----------------------------------
Y
------
A
-
K
A
V
M
D
R
I
L
K
D
H
Q
-
I
V
V
D
I
P
H
G
E
A
W
L
-
R
D
D
E
E
-
R
P
M
I
-
L
I
A
G
G
T
G
F
S
Y
A
R
S
I
L
L
T
A
L
A
R
NP-
N
--
R
D
I
T
---
I
Y
W
G
G
R
E
E
Q
H
L
Y
D
-----
L
C
E
L
E
A
------
L
SLK
H
--------
P
G--
L
Q
----
V
V
-----------
P
V
V
---
E
Q
------
P
EAGWRGR--
T
---------
G
T
V
------
L
T
-------
A
V
L
Q
----
D
H
GT------
L
A
---------------
E
H
-
D
I
Y
I
A
G
R
F
E
M
A
K
I
A
R
D
L
F
C
S
E
R
N
A
R
E
D
R
L
F
G
D
A
F
A
F
--------------------------------------------------------------------------------------------------
71
HHSearch
52.83
21%
-52
- C2 -
-
4WQM
3
TMOF_PSEME
A:
[99-326]
---
P
P
K
R
F
S
T
R
V
V
S
K
R
F
L
S
D
---
E
M
F
E
L
R
L
E
A
E
Q
--
K
V
-
V
F
S
P
G
Q
Y
F
M
V
D
V
-
P
-----
E
--------------------------------
L
G
T
R
A
Y
S
A
A
N
P
V
D
-
G
N
T
L
T
L
I
V
K
A
---------
V
---------------
P
N
-----
G
K
V
------
S
-
C
A
L
A
N
--
E
T
I
E
T
-
L
Q
L
D
G
P
Y
G
L
S
V
L
-
K
T
A
D
E
-
T
Q
S
V
-
F
I
A
G
G
S
G
I
A
P
M
V
S
M
V
N
T
L
I
A
Q
GY-
E
--
K
P
I
T
---
V
F
Y
G
S
R
L
E
A
E
L
E
A
-----
A
E
T
L
F
G
------
W
---
K
--------
E
N--
L
K
----
L
I
-----------
N
V
S
---
S
S
------
V
VGNSESSYP
T
---------
G
Y
V
------
H
--------
E
I
I
P
----
E
Y
MEG-----
L
L
---------------
G
A
-
E
F
Y
L
C
G
P
P
Q
M
I
N
S
V
Q
K
L
L
M
I
E
N
K
V
P
F
E
A
I
H
F
D
R
F
F
---------------------------------------------------------------------------------------------------
77
HHSearch
51.77
21%
15
- C2 -
-
1GVH
2
HMP_ECOLI
A:
[150-394]
----
E
G
T
R
D
F
R
I
V
A
K
T
P
R
S
A
---
L
I
T
S
F
E
L
E
P
V
D
G
G
A
V
A
E
Y
R
P
G
Q
Y
L
G
V
W
L
-
K
-----
P
EGFP
H
---------------------------
Q
E
I
R
Q
Y
S
L
T
R
K
P
D
G
-
K
G
Y
R
I
A
V
K
R
---------
E
---------------
E
G
-----
G
Q
V
------
S
-
N
W
L
H
N
H
A
N
V
G
D
V
-
V
K
L
V
A
P
A
G
D
F
F
M
-
A
V
A
D
D
-
T
P
V
T
-
L
I
S
A
G
V
G
Q
T
P
M
L
A
M
L
D
T
L
A
K
A
GH-
T
--
A
Q
V
N
---
W
F
H
A
A
E
N
G
D
V
H
A
F
-----
A
D
E
V
K
E
------
L
---
G
Q
S
L-----
P
R
--
F
T
----
A
H
-----------
T
W
Y
---
R
Q
------
P
S
E
A
D
R
A
---
K
---------
G
Q
F
DSEGLM
D
L
---
S
----
K
L
E
----
G
A
FS------
D
P
---------------
T
M
-
Q
F
Y
L
C
G
P
V
G
F
M
Q
F
T
A
K
Q
L
V
-
D
L
G
V
K
Q
E
N
I
H
Y
E
C
F
G
P
H
K
------------------------------------------------------------------------------------------------
70
HHSearch
51.22
19%
13
- C2 -
-
4P6V
1
NQRF_VIBCH
F:
[130-408]
----
V
K
K
W
E
C
T
V
I
S
N
D
N
K
A
T
---
F
I
K
E
L
K
L
A
I
P
D
G
E
S
V
-
P
F
R
A
G
G
Y
I
Q
I
E
A
-
P
-----
A
H
H
V
K
YADFDVPEKYR
G
D
W
D
K
F
NLFR
Y
E
S
K
V
D
E
P
I
I
R
A
Y
S
M
A
N
Y
P
E
E
F
G
I
I
M
L
N
V
R
I
ATPPPNNPN
V
---------------
P
P
-----
G
Q
M
------
S
-
S
Y
I
W
-
S
L
K
A
G
D
K
-
C
T
I
S
G
P
F
G
E
F
F
A
-
K
D
T
-
D
-
A
E
M
V
-
F
I
G
G
G
A
G
M
A
P
M
R
S
H
I
F
D
Q
L
K
R
LKS
K
--
R
K
M
S
---
Y
W
Y
G
A
R
S
K
R
E
M
F
Y
-----
V
E
D
F
D
G
------
L
---
A
A
E
N
-----
D
N--
F
V
----
W
H
-----------
C
A
L
---
S
D
------
P
QPEDNWTGY
T
---------
G
F
I
------
H
N
V
L
Y
E
---
N
Y
L
K
----
D
H
EA------
P
E
---------------
D
C
-
E
Y
Y
M
C
G
P
P
M
M
N
A
A
V
I
N
M
L
K
-
N
L
G
V
E
E
E
N
I
L
L
D
D
F
G
G
--------------------------------------------------------------------------------------------------
50
Fugue
50.64
32%
-97
- C2 -
-
2PIA
1
?
?:
[104-223]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
F
P
L
-
D
K
R
-
A
-
K
S
F
I
-
L
V
A
G
G
I
G
I
T
P
M
L
S
M
A
R
Q
L
R
A
E
---
G
L-
R
S
F
R
---
L
Y
Y
L
T
R
D
P
E
G
T
A
F
-----
F
D
E
L
T
S
------
D
---
E
--------
W
---
R
S
----
D
V
-----------
K
I
H
H
DH
G
D
------
P
---------
T
---------
K
A
F
------
D
F
---
W
---
S
V
F
E
----
K
S
--------
K
P
---------------
A
Q
-
H
V
Y
C
C
G
P
Q
A
L
M
D
T
V
R
D
M
T
G
-
H
--
W
P
S
G
T
V
H
F
E
------------------------------------------------------------------------------------------------------
69
HHSearch
49.90
22%
-12
- C2 -
-
1KRH
1
BENC_ACIAD
A:
[106-337]
----
I
H
H
F
E
G
T
L
A
R
V
E
N
L
S
D
---
S
T
I
T
F
D
I
Q
L
D
D
G
Q
P
D
I
H
F
L
A
G
Q
Y
V
N
V
T
L
-
P
G----
T
--------------------------------
T
E
T
R
S
Y
S
F
S
S
Q
P
G
N
-
R
L
T
G
F
V
V
R
N
---------
V
---------------
P
Q
-----
G
K
M
------
S
-
E
Y
L
S
V
Q
A
K
A
G
D
K
-
M
S
F
T
G
P
F
G
S
F
Y
L
-
R
D
V
-
K
-
R
P
V
L
-
M
L
A
G
G
T
G
I
A
P
F
L
S
M
L
Q
V
L
E
Q
K
GS-
E
--
H
P
V
R
---
L
V
F
G
V
T
Q
D
C
D
L
V
A
-----
L
E
Q
L
D
A
------
L
---
Q
Q
K
L
-----
P
W--
F
E
----
Y
R
-----------
T
V
V
---
A
H
------
A
---------
E
SQH------
E
R
K
G-----
Y
V
---
T
---
G
H
I
E
----
Y
D
WLN-----
G
G
---------------
E
V
-
D
V
Y
L
C
G
P
V
P
M
V
E
A
V
R
S
W
L
D
-
T
Q
G
I
Q
P
A
N
F
L
F
E
K
F
S
A
--------------------------------------------------------------------------------------------------
78
HHSearch
48.96
19%
13
- C2 -
-
4U9U
1
NQRF_VIBCH
A:
[3-281]
----
V
K
K
W
E
C
T
V
I
S
N
D
N
K
A
T
---
F
I
K
E
L
K
L
A
I
P
D
G
E
S
V
-
P
F
R
A
G
G
Y
I
Q
I
E
A
-
P
-----
A
H
H
V
K
YADFDVPEKYR
G
D
W
D
K
F
NLFR
Y
E
S
K
V
D
E
P
I
I
R
A
Y
S
M
A
N
Y
P
E
E
F
G
I
I
M
L
N
V
R
I
ATPPPNNPN
V
---------------
P
P
-----
G
Q
M
------
S
-
S
Y
I
W
-
S
L
K
A
G
D
K
-
C
T
I
S
G
P
F
G
E
F
F
A
-
K
D
T
-
D
-
A
E
M
V
-
F
I
G
G
G
A
G
M
A
P
M
R
S
H
I
F
D
Q
L
K
R
LKS
K
--
R
K
M
S
---
Y
W
Y
G
A
R
S
K
R
E
M
F
Y
-----
V
E
D
F
D
G
------
L
---
A
A
E
N
-----
D
N--
F
V
----
W
H
-----------
C
A
L
---
S
D
------
P
QPEDNWTGY
T
---------
G
F
I
------
H
----
N
---
V
L
Y
E
N
YLK
D
H
EA------
P
E
---------------
D
C
-
E
Y
Y
M
C
G
P
P
M
M
N
A
A
V
I
N
M
L
K
-
N
L
G
V
E
E
E
N
I
L
L
D
D
F
G
G
--------------------------------------------------------------------------------------------------
72
HHSearch
48.60
21%
1
- C2 -
-
4EH1
5
HMP_VIBCH
B:
[2-238]
-----
D
G
R
T
F
V
V
R
E
K
Q
V
E
S
A
---
Y
V
T
S
F
V
L
V
P
A
D
G
G
A
V
L
D
Y
Q
P
G
Q
Y
I
G
I
E
V
-
T
-----
P
E
GSD
Y
---------------------------
R
E
I
R
Q
Y
S
L
S
H
A
S
N
G
-
R
E
Y
R
I
S
V
K
R
---------
E
---------------
G
V
GSDN
P
G
L
V
------
S
-
H
Y
L
H
N
N
V
K
V
G
D
S
-
V
K
L
Y
A
P
A
G
D
F
F
Y
-
V
E
R
-
E
-
R
P
V
V
-
L
I
S
A
G
V
G
A
T
P
M
Q
A
I
L
H
T
L
A
K
Q
N--
K
--
S
G
V
T
---
Y
L
Y
A
C
N
S
A
K
E
H
T
F
-----
A
Q
E
T
A
Q
------
L
---
I
--------
A
Q
Q
G
W
M
----
Q
Q
-----------
V
W
Y
---
R
D
------
E
S
A
D
DVL---
Q
---------
G
E
M
------
Q
L
---
A
---
E
L
I
L
----
P
---------
I
E
---------------
D
G
-
D
F
Y
L
C
G
P
I
G
F
M
Q
Y
V
V
K
Q
L
L
-
A
L
G
V
D
K
A
R
I
H
Y
E
V
F
G
P
H
-------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
48.60
26%
-31
- C2 -
-
4WQM
2
TMOF_PSEME
A:
[130-325]
----------------------------------------
F
S
P
G
Q
Y
F
M
V
D
V
-
P
-----
E
--------------------------------
L
G
T
R
A
Y
S
A
A
N
P
V
-
D
G
N
T
L
T
L
I
V
K
A
---------
V
---------------
P
N
----
G
K
V
S
------
C
-
A
L
----
A
N
E
T
I
E
T
L
Q
L
D
G
P
Y
G
L
S
V
L
-
K
T
A
-
D
E
T
Q
S
V
-
F
I
A
G
G
S
G
I
A
P
M
V
S
M
V
N
T
L
I
A
Q
---
G
--
Y
E
K
P
---
I
T
V
F
Y
G
S
R
L
E
A
E
L
-----
E
A
A
E
T
L
------
F
---
G
--------
W
---
K
E
----
N
L
-----------
K
L
I
---
N
V
------
S
---------
S
---------
S
V
V
------
G
N
---
S
---
E
--
S
----
S
Y
--------
P
T
GYVHEIIPEYMEGLL
G
A
-
E
F
Y
L
C
G
P
P
Q
M
I
N
S
V
Q
K
L
L
M
I
E
N
K
V
P
F
E
A
I
H
F
D
R
F
----------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
48.43
23%
9
- C2 -
-
1CQX
2
HMP_CUPNH
A:
[168-397]
-----------------------
V
I
T
S
F
I
L
E
P
A
D
G
G
P
V
V
N
F
E
P
G
Q
Y
T
S
V
A
I
-
D
-----
V
PALG
L
---------------------------
Q
Q
I
R
Q
Y
S
L
-
S
D
M
P
N
G
R
T
Y
R
I
S
V
K
R
--------------------------
E
----
G
G
G
P
QPPGY
V
S
-
N
L
L
H
D
H
V
N
V
G
D
Q
-
V
K
L
A
A
P
Y
G
S
F
H
I
D
V
D
A
-
K
-
T
P
I
V
-
L
I
S
G
G
V
G
L
T
P
M
V
-
S
M
L
K
V
A
L
Q
---
A
--
P
P
R
Q
V
V
F
V
H
G
A
R
N
S
A
V
H
-
A
M
-----
R
D
R
L
R
E
------
A
---
A
--------
K
---
T
Y
EN
L
D
L
F
-----------
V
F
Y
---
D
Q
PLPEDV
Q
---------
G
---------
R
D
Y
------
D
Y
---
P
---
G
L
V
D
----
V
K
QIEKSILL
P
D
---------------
A
D
-
Y
-
Y
I
C
G
P
I
P
F
M
R
M
Q
H
D
A
L
K
-
N
L
G
I
H
E
A
R
I
H
Y
E
V
F
G
---------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
47.92
25%
-16
- C2 -
-
1KRH
1
BENC_ACIAD
A:
[109-337]
-------
F
E
G
T
L
A
R
V
E
N
L
S
D
---
S
T
I
T
F
D
I
Q
L
D
D
G
Q
P
D
I
H
F
L
A
G
Q
Y
V
N
V
T
L
P
G
-----
T
--------------------------------
T
E
T
R
S
Y
S
F
S
S
Q
P
G
N
R
L
T
G
F
V
-
V
R
N
---------
V
---------------
P
Q
----
G
K
M
-------
S
-
E
Y
L
S
V
Q
A
K
A
G
D
K
-
M
S
F
T
G
P
F
G
S
F
Y
L
-
R
D
V
-
K
-
R
P
V
L
-
M
L
A
G
G
T
G
I
A
P
F
L
S
M
L
Q
V
L
E
Q
K
---
G
--
S
E
H
P
---
V
R
L
V
F
G
V
T
Q
D
C
D
L
VA
L
E
Q
L
D
A
L
Q
Q
------
K
---
L
P
W
F
E
Y
R
T
V
V
---
A
H
----
A
E
-----------
S
Q
H
---
E
R
------
K
---------
G
---------
Y
V
T
------
G
H
---
I
---
E
Y
D
W
----
L
N
--------
G
G
---------------
E
V
-
D
V
Y
L
C
G
P
V
P
M
V
E
A
V
R
S
W
L
D
-
T
Q
G
I
Q
P
A
N
F
L
F
E
K
F
S
A
--------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
46.78
23%
-0
- C2 -
-
3OZW
1
HMP_CUPNH
A:
[168-397]
-----------------------
V
I
T
S
F
I
L
E
P
A
D
G
G
P
V
V
N
F
E
P
G
Q
Y
T
S
V
A
I
-
D
-----
V
PALG
L
---------------------------
Q
Q
I
R
Q
Y
S
L
-
S
D
M
P
N
G
R
S
Y
R
I
S
V
K
R
--------------------------
E
----
G
G
G
P
QPPGY
V
S
-
N
L
L
H
D
H
V
N
V
G
D
Q
-
V
K
L
A
A
P
Y
G
S
F
H
I
D
V
D
A
-
K
-
T
P
I
V
-
L
I
S
G
G
V
G
L
T
P
M
V
-
S
M
L
K
V
A
L
Q
---
A
--
P
P
R
Q
V
V
F
V
H
G
A
R
N
S
A
V
H
-
A
M
-----
R
D
R
L
R
E
------
A
---
A
--------
K
---
T
Y
EN
L
D
L
F
-----------
V
F
Y
---
D
Q
PLPEDV
Q
---------
G
---------
R
D
Y
------
D
Y
---
P
---
G
L
V
D
----
V
K
QIEKSILL
P
D
---------------
A
D
-
Y
-
Y
I
C
G
P
I
P
F
M
R
M
Q
H
D
A
L
K
-
N
L
G
I
H
E
A
R
I
H
Y
E
V
F
G
---------------------------------------------------------------------------------------------------
76
HHSearch
46.52
19%
-1
- C2 -
-
2EIX
4
?
A:
[7-241]
--
N
P
N
E
Y
K
K
F
M
L
R
E
K
Q
I
I
N
H
---
N
T
R
L
F
R
F
N
L
H
H
P
E
D
V
V
G
L
P
I
G
Q
H
M
S
V
K
A
-
T
V
DG--
K
--------------------------------
E
I
Y
R
P
Y
T
P
V
S
S
D
D
E
K
G
Y
F
D
L
I
I
K
V
---------
Y
---------------
E
K
-----
G
Q
M
------
S
-
Q
Y
I
D
-
H
L
N
P
G
D
F
-
L
Q
V
R
G
P
K
G
Q
F
D
Y
-
K
P
N
M
V
-
K
E
M
G
-
M
I
A
G
G
T
G
I
T
P
M
L
Q
V
A
R
A
I
I
K
N
PKE
K
--
T
I
I
N
---
L
I
F
A
N
V
N
E
D
D
I
L
L
-----
R
T
E
L
D
D
------
M
---
A
K
K
Y
-----
S
N--
F
K
----
V
Y
-----------
Y
V
L
---
N
N
------
P
PAGWTGG--
V
---------
G
F
V
------
S
A
---
D
M
I
K
Q
H
F
S
----
P
P
--------
S
S
---------------
D
I
-
K
V
M
M
C
G
P
P
M
M
N
K
A
M
Q
G
H
L
E
-
T
L
G
Y
T
P
E
Q
W
F
--------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
46.48
23%
3
- C2 -
-
3OZV
1
HMP_CUPNH
B:
[168-397]
-----------------------
V
I
T
S
F
I
L
E
P
A
D
G
G
P
V
V
N
F
E
P
G
Q
Y
T
S
V
A
I
-
D
-----
V
PALGL---------------------------
Q
Q
I
R
Q
Y
S
L
-
S
D
M
P
N
G
R
S
Y
R
I
S
V
K
R
--------------------------
E
----
G
G
G
P
QPPGYV
S
-
N
L
L
H
D
H
V
N
V
G
D
Q
-
V
K
L
A
A
P
Y
G
S
F
H
I
D
V
D
A
-
K
-
T
P
I
V
-
L
I
S
G
G
V
G
L
T
P
M
V
-
S
M
L
K
V
A
L
Q
---
A
--
P
P
R
Q
VVF
V
H
G
A
R
N
S
A
V
H
-
A
M
-----
R
D
R
L
R
E
------
A
---
A
--------
K
---
T
Y
ENLD
L
F
-----------
V
F
Y
---
D
Q
PLPEDV
Q
---------
G
---------
R
D
Y
------
D
Y
---
P
---
G
L
V
D
----
V
K
QIEKSILL
P
D
---------------
A
D
-
Y
-
Y
I
C
G
P
I
P
F
M
R
M
Q
H
D
A
L
K
-
N
L
G
I
H
E
A
R
I
H
Y
E
V
F
G
---------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
46.18
23%
6
- C2 -
-
3OZU
1
HMP_CUPNH
A:
[168-397]
-----------------------
V
I
T
S
F
I
L
E
P
A
D
G
G
P
V
V
N
F
E
P
G
Q
Y
T
S
V
A
I
-
D
-----
V
PALG
L
---------------------------
Q
Q
I
R
Q
Y
S
L
-
S
D
M
P
N
G
R
S
Y
R
I
S
V
K
R
--------------------------
E
----
G
G
G
P
QPPGY
V
S
-
N
L
L
H
D
H
V
N
V
G
D
Q
-
V
K
L
A
A
P
Y
G
S
F
H
I
D
V
D
A
-
K
-
T
P
I
V
-
L
I
S
G
G
V
G
L
T
P
M
V
-
S
M
L
K
V
A
L
Q
---
A
--
P
P
R
Q
V
V
F
V
H
G
A
R
N
S
A
V
H
-
A
M
-----
R
D
R
L
R
E
------
A
---
A
--------
K
---
T
Y
EN
L
D
L
F
-----------
V
F
Y
---
D
Q
PLPEDV
Q
---------
G
---------
R
D
Y
------
D
Y
---
P
---
G
L
V
D
----
V
K
QIEKSILL
P
D
---------------
A
D
-
Y
-
Y
I
C
G
P
I
P
F
M
R
M
Q
H
D
A
L
K
-
N
L
G
I
H
E
A
R
I
H
Y
E
V
F
G
---------------------------------------------------------------------------------------------------