@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VTQ1: (2017-12-14 )
MRFVDEAVITVEAGDGGNGVASFRREKFVPFGGPDGGDGGRGGSIYIQADDDTSTLVDYRYTRKLRAERGKNGAGANCTGRGGEDVVLKVPVGTTIVDTDSGDIIGDLVEDGQRVMVASGGEGGLGNTHFKSSTNRAPRKCTTGTKGEFREIRLELKVLADVGLLGMPNAGKSTFIRAVSAAKPKVADYPFTTMVPNLGVVDADRHRSFVMADIPGLIEGAAEGAGLGIRFLKHLARTRILLHIIDVQPIDGSDPAHNAKAIMNELAKFSPTLANLPIVLVLNKLDQIAEESREEWCQHILDELQWTGPVFKTSGLLEEGTKEVVYYLMDQIEQQREREVEDPEYAAEVRAFREQLEAETREQTIAAKEAYRAMRKAQRLESMMDDDDDFDDDEDDGDVESIYVRD
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160...-....170.......180-...-....190.......200..-.....210.......220-.-------.---...-..-.230.......-240.......250.-......260.......--270.......280......----.290----.......300....-----...------.---310..---.....320.......330.....--------------..340.......350.......360.......370.......380.......390.......400....-
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MRFV
D
E
A
V
I
T
V
EAGDGGN
G
V
A
S
F
R
REKFVPFGGPDGGDGGRG
G
S
I
Y
I
Q
ADDDT
S
T
L
V
D
Y
R
Y
T
R
K
L
R
A
ERGKNGAGANCTGRGG
E
D
V
V
L
KVPVG
T
T
I
V
DTDSG
D
I
I
G
D
L
V
EDG
Q
R
V
M
V
A
SGGEGGLGN
T
H
FKSSTNRAPRKCTTGTKG
E
F
R
E
I
R
L
E
L
K
V
L
A
DVGLL-GMPNAG
K
S
T
F
I
R
A
VSAA-KPK-VADYPFTTMVPNLGVVD
A
D
-RH
R
S
F
V
MADI
P
G
L
I
E
GA--A-------E---GA
G
-
L
G
-
I
R
F
L
K
H
L
A
R
T
R
-
I
L
L
H
I
I
D
VQPIDGS-DPAH
N
A
K
A
I
M
N
E
L
A
K
F--SPTLANLP
I
V
L
V
L
N
K
L
D
Q
I
----
A
E
E
S
----
R
E
E
W
C
Q
H
I
-
L
D
ELQ-----WTG------P---VFKTS---G
L
L
E
E
G
T
K
E
V
V
Y
Y
L
M
D
Q
I
E
Q
Q
R
E--------------REVED
P
E
Y
A
A
E
V
R
A
F
R
E
Q
L
E
A
E
T
R
E
Q
T
I
A
A
K
E
A
Y
R
A
M
R
K
A
Q
R
L
E
S
M
MDDDDDFDDDEDDGDV
E
S
I
Y
VRD-
1
PsiBlast_PDB
88.57
59%
-75
- C1 -
-
5M04
1
OBG_ECOLI
A:
[21-352]
M
K
F
V
D
E
A
S
I
L
V
V
A
G
D
G
G
N
G
C
V
S
F
R
R
E
K
Y
I
P
K
G
G
P
D
G
G
D
G
G
D
G
G
D
V
W
M
E
A
D
E
N
L
N
T
L
I
D
Y
R
F
E
K
S
F
R
A
E
R
G
Q
N
G
A
S
R
D
C
T
G
K
R
G
K
D
V
T
I
K
V
P
V
G
T
R
V
I
D
Q
G
T
G
E
T
M
G
D
M
T
K
H
G
Q
R
L
L
V
A
K
G
G
W
H
G
L
G
N
T
R
F
K
S
----
T
P
R
Q
K
T
N
G
T
P
G
D
K
R
E
L
L
L
E
L
M
L
L
A
D
V
G
M
L
-
G
M
P
N
A
G
K
S
T
F
I
R
A
V
S
A
A
-
K
P
K
-
V
A
D
Y
P
F
T
T
L
V
P
S
L
G
V
V
R
M
D
-
N
E
K
S
F
V
V
A
D
I
P
G
L
I
E
G
A
--
A
-------
E
---
G
A
G
-
L
G
-
I
R
F
L
K
H
L
E
R
C
R
-
V
L
L
H
L
I
D
I
D
P
I
D
G
T
-
D
P
V
E
N
A
R
I
I
I
S
E
L
E
K
Y
--
S
Q
D
L
A
T
K
P
R
W
L
V
F
N
K
I
D
L
L
----
D
K
V
E
----
A
E
E
K
A
K
A
I
-
A
E
A
L
G
-----
W
E
D
------
K
---
Y
Y
L
I
S
---
A
A
S
G
L
G
V
K
D
L
C
W
D
V
M
T
F
I
-----------------------------------------------------------------------------------------
33
HHSearch
86.62
59%
-59
- C1 -
-
5M04
1
OBG_ECOLI
A:
[21-356]
M
K
F
V
D
E
A
S
I
L
V
V
A
G
D
G
G
N
G
C
V
S
F
R
R
E
K
Y
I
P
K
G
G
P
D
G
G
D
G
G
D
G
G
D
V
W
M
E
A
D
E
N
L
N
T
L
I
D
Y
R
F
E
K
S
F
R
A
E
R
G
Q
N
G
A
S
R
D
C
T
G
K
R
G
K
D
V
T
I
K
V
P
V
G
T
R
V
I
D
Q
G
T
G
E
T
M
G
D
M
T
K
H
G
Q
R
L
L
V
A
K
G
G
W
H
G
L
G
N
T
R
F
K
S
----
T
P
R
Q
K
T
N
G
T
P
G
D
K
R
E
L
L
L
E
L
M
L
L
A
D
V
G
M
L
-
G
M
P
N
A
G
K
S
T
F
I
R
A
V
S
A
A
-
K
P
K
-
V
A
D
Y
P
F
T
T
L
V
P
S
L
G
V
V
R
M
D
-
N
E
K
S
F
V
V
A
D
I
P
G
L
I
E
G
A
--
A
-------
E
---
G
A
G
-
L
G
-
I
R
F
L
K
H
L
E
R
C
R
-
V
L
L
H
L
I
D
I
D
P
I
D
G
T
-
D
P
V
E
N
A
R
I
I
I
S
E
L
E
K
Y
--
S
Q
D
L
A
T
K
P
R
W
L
V
F
N
K
I
D
L
L
D---
K
V
E
A
----
E
E
K
A
-
K
A
I
-
A
E
A
L
G
-----
W
E
D
------
K
---
Y
Y
L
I
S
---
A
A
S
G
L
G
V
K
D
L
C
W
D
V
M
T
F
I
I
E
N
P
-------------------------------------------------------------------------------------
3
PsiBlast_PDB
79.37
47%
-75
- C1 -
-
1UDX
1
OBG_THET8
A:
[2-327]
--
F
Q
D
V
L
V
I
T
V
A
A
G
R
G
G
D
G
A
V
S
F
R
R
E
K
F
V
P
K
G
G
P
D
G
G
D
G
G
R
G
G
S
V
Y
L
R
A
R
G
S
V
D
S
L
S
R
L
S
-
K
R
T
Y
K
A
E
D
G
E
H
G
R
G
S
Q
Q
H
G
R
G
G
E
D
L
V
I
E
V
P
R
G
T
R
V
F
D
A
D
T
G
E
L
L
A
D
L
T
E
E
G
Q
T
V
L
V
A
R
G
G
A
G
G
R
G
N
M
H
F
V
S
P
T
R
Q
A
P
R
F
A
E
A
G
E
E
G
E
K
R
R
L
R
L
E
L
M
L
I
A
D
V
G
L
V
-
G
Y
P
N
A
G
K
S
S
L
L
A
A
M
T
R
A
-
H
P
K
-
I
A
P
Y
P
F
T
T
L
S
P
N
L
G
V
V
E
V
S
-
E
E
E
R
F
T
L
A
D
I
P
G
I
I
E
G
A
--
S
-------
E
---
G
K
G
-
L
G
-
L
E
F
L
R
H
I
A
R
T
R
-
V
L
L
Y
V
L
D
A
----
A
D
-
E
P
L
K
T
L
E
T
L
R
K
E
V
G
A
Y
--
D
P
A
L
L
R
R
P
S
L
V
A
L
N
K
V
D
L
L
----
E
E
E
A
----
V
K
A
L
A
D
A
L
-
A
R
E
G
L
-----
A
V
L
------
P
---
V
S
A
L
T
---
G
A
G
L
P
A
L
K
E
A
L
H
A
L
V
--------------------------------------------------------------------------------------------
54
Fugue
78.99
41%
-52
- C1 -
-
1UDX
1
OBG_THET8
A:
[1-416]
M
-
F
Q
D
V
L
V
I
T
V
A
A
G
R
G
G
D
G
A
V
S
F
R
R
E
K
F
V
P
K
G
G
P
D
G
G
D
G
G
R
G
G
S
V
Y
L
R
A
R
G
S
V
D
S
L
S
R
L
S
-
K
R
T
Y
K
A
E
D
G
E
H
G
R
G
S
Q
Q
H
G
R
G
G
E
D
L
V
I
E
V
P
R
G
T
R
V
F
D
A
D
T
G
E
L
L
A
D
L
T
E
E
G
Q
T
V
L
V
A
R
G
G
A
G
G
R
G
N
M
H
F
V
S
P
T
R
Q
A
P
R
F
A
E
A
G
E
E
G
E
K
R
R
L
R
L
E
L
M
L
I
A
D
V
G
L
V
-
G
Y
P
N
A
G
K
S
S
L
L
A
A
M
T
R
A
-
H
P
K
-
I
A
P
Y
P
F
T
T
L
S
P
N
L
G
V
V
E
V
S
-
E
E
E
R
F
T
L
A
D
I
P
G
I
I
E
G
A
--
S
-------
E
---
G
K
G
-
L
G
-
L
E
F
L
R
H
I
A
R
T
R
-
V
L
L
Y
V
L
D
A
A
D
-----
E
P
L
K
T
L
E
T
L
R
K
E
V
G
A
Y
--
D
P
A
L
L
R
R
P
S
L
V
A
L
N
K
V
D
L
L
----
E
E
E
A
----
V
K
A
L
A
D
A
L
-
A
R
E
G
L
--------------
A
---
V
L
P
V
S
---
A
L
T
G
A
G
L
P
A
L
K
E
A
L
H
A
L
V
R
S
T
P
P
PEMPKPVPQA
G
V
E
V
V
P
V
A
E
G
V
Y
E
V
R
A
P
E
V
E
R
Y
L
A
R
I
K
G
D
L
M
E
A
A
G
Y
L
Q
E
V
F
R
R
Q
G
V
E
A
A
L
R
A
K
G
V
R
A
G
D
L
V
R
I
G
G
L
E
F
E
Y
I
P
E
V
34
HHSearch
78.14
48%
-46
- C1 -
-
1LNZ
-
OBG_BACSU
A:
[1-332]
-
M
F
V
D
Q
V
K
V
Y
V
K
G
G
D
G
G
N
G
M
V
A
F
R
R
E
K
Y
V
P
K
G
G
P
A
G
G
D
G
G
K
G
G
D
V
V
F
E
V
D
E
G
L
R
T
L
M
D
F
R
Y
K
K
H
F
K
A
I
R
G
E
H
G
M
S
K
N
Q
H
G
R
N
A
D
D
M
V
I
K
V
P
P
G
T
V
V
T
D
D
D
T
K
Q
V
I
A
D
L
T
E
H
G
Q
R
A
V
I
A
R
G
G
R
G
G
R
G
N
S
R
F
A
T
P
A
N
P
A
P
Q
L
S
E
N
G
E
P
G
K
E
R
Y
I
V
L
E
L
K
V
L
A
D
V
G
L
V
-
G
F
P
S
V
G
K
S
T
L
L
S
V
V
S
S
A
-
K
P
K
-
I
A
D
Y
H
F
T
T
L
V
P
N
L
G
M
V
E
T
D
-
D
G
R
S
F
V
M
A
D
L
P
G
L
I
E
G
A
--
H
-------
Q
---
G
V
G
-
L
G
-
H
Q
F
L
R
H
I
E
R
T
R
-
V
I
V
H
V
I
D
M
S
G
L
E
G
R
-
D
P
Y
D
D
Y
L
T
I
N
Q
E
L
S
E
Y
--
N
L
R
L
T
E
R
P
Q
I
I
V
A
N
K
M
D
M
P
E---
A
A
E
N
----
L
E
A
F
-
K
E
K
-
L
T
D
D
--------
Y
------
P
---
V
F
P
I
S
---
A
V
T
R
E
G
L
R
E
L
L
F
E
V
A
N
Q
L
E
N
T
P
-------------------------------------------------------------------------------------
2
PsiBlast_PDB
78.11
46%
-45
- C1 -
-
1LNZ
-
OBG_BACSU
A:
[2-340]
--
F
V
D
Q
V
K
V
Y
V
K
G
G
D
G
G
N
G
M
V
A
F
R
R
E
K
Y
V
P
K
G
G
P
A
G
G
D
G
G
K
G
G
D
V
V
F
E
V
D
E
G
L
R
T
L
M
D
F
R
Y
K
K
H
F
K
A
I
R
G
E
H
G
M
S
K
N
Q
H
G
R
N
A
D
D
M
V
I
K
V
P
P
G
T
V
V
T
D
D
D
T
K
Q
V
I
A
D
L
T
E
H
G
Q
R
A
V
I
A
R
G
G
R
G
G
R
G
N
S
R
F
A
T
P
A
N
P
A
P
Q
L
S
E
N
G
E
P
G
K
E
R
Y
I
V
L
E
L
K
V
L
A
D
V
G
L
V
-
G
F
P
S
V
G
K
S
T
L
L
S
V
V
S
S
A
-
K
P
K
-
I
A
D
Y
H
F
T
T
L
V
P
N
L
G
M
V
E
T
D
-
D
G
R
S
F
V
M
A
D
L
P
G
L
I
E
G
A
--
H
-------
Q
---
G
V
G
-
L
G
-
H
Q
F
L
R
H
I
E
R
T
R
-
V
I
V
H
V
I
D
M
S
G
L
E
G
R
-
D
P
Y
D
D
Y
L
T
I
N
Q
E
L
S
E
Y
--
N
L
R
L
T
E
R
P
Q
I
I
V
A
N
K
M
D
M
P
E---
A
A
E
N
----
L
E
A
F
K
E
K
L
-
T
D
D
Y
---------------
P
---
V
F
P
I
S
---
A
V
T
R
E
G
L
R
E
L
L
F
E
V
A
N
Q
L
E
N
T
P
E
--------------
F
P
L
Y
D
E
E
---------------------------------------------------------------
36
HHSearch
75.94
47%
-54
- C1 -
-
1UDX
1
OBG_THET8
A:
[1-332]
-
M
F
Q
D
V
L
V
I
T
V
A
A
G
R
G
G
D
G
A
V
S
F
R
R
E
K
F
V
P
K
G
G
P
D
G
G
D
G
G
R
G
G
S
V
Y
L
R
A
R
G
S
V
D
S
L
S
R
L
S
-
K
R
T
Y
K
A
E
D
G
E
H
G
R
G
S
Q
Q
H
G
R
G
G
E
D
L
V
I
E
V
P
R
G
T
R
V
F
D
A
D
T
G
E
L
L
A
D
L
T
E
E
G
Q
T
V
L
V
A
R
G
G
A
G
G
R
G
N
M
H
F
V
S
P
T
R
Q
A
P
R
F
A
E
A
G
E
E
G
E
K
R
R
L
R
L
E
L
M
L
I
A
D
V
G
L
V
-
G
Y
P
N
A
G
K
S
S
L
L
A
A
M
T
R
A
-
H
P
K
-
I
A
P
Y
P
F
T
T
L
S
P
N
L
G
V
V
E
V
S
-
E
E
E
R
F
T
L
A
D
I
P
G
I
I
E
G
A
--
S
-------
E
---
G
K
G
-
L
G
-
L
E
F
L
R
H
I
A
R
T
R
-
V
L
L
Y
V
L
D
A
A
D
E
-----
P
L
K
T
L
E
T
L
R
K
E
V
G
A
Y
--
D
P
A
L
L
R
R
P
S
L
V
A
L
N
K
V
D
L
L
E---
E
E
A
V
-----
K
A
L
-
A
D
A
-
L
A
R
E
G
-------
L
------
A
---
V
L
P
V
S
---
A
L
T
G
A
G
L
P
A
L
K
E
A
L
H
A
L
V
R
S
T
P
P
------------------------------------------------------------------------------------
35
HHSearch
74.17
48%
-41
- C1 -
-
1LNZ
1
OBG_BACSU
B:
[1-332]
-
M
F
V
D
Q
V
K
V
Y
V
K
G
G
D
G
G
N
G
M
V
A
F
R
R
E
K
Y
V
P
K
G
G
P
A
G
G
D
G
G
K
G
G
D
V
V
F
E
V
D
E
G
L
R
T
L
M
D
F
R
Y
K
K
H
F
K
A
I
R
G
E
H
G
M
S
K
N
Q
H
G
R
N
A
D
D
M
V
I
K
V
P
P
G
T
V
V
T
D
D
D
T
K
Q
V
I
A
D
L
T
E
H
G
Q
R
A
V
I
A
R
G
G
R
G
G
R
G
N
S
R
F
A
T
P
A
N
P
A
P
Q
L
S
E
N
G
E
P
G
K
E
R
Y
I
V
L
E
L
K
V
L
A
D
V
G
L
V
-
G
F
P
S
V
G
K
S
T
L
L
S
V
V
S
S
A
-
K
P
K
-
I
---------
P
N
L
G
M
V
E
T
D
-
D
G
R
S
F
V
M
A
D
L
P
G
L
I
E
G
----------------------
H
Q
F
L
R
H
I
E
R
T
R
-
V
I
V
H
V
I
D
M
S
G
L
E
G
R
-
D
P
Y
D
D
Y
L
T
I
N
Q
E
L
S
E
Y
--
N
L
R
L
T
E
R
P
Q
I
I
V
A
N
K
M
D
M
P
E---
A
A
E
N
----
L
E
A
F
-
K
E
K
-
L
T
D
D
--------
Y
------
P
---
V
F
P
I
S
---
A
V
T
R
E
G
L
R
E
L
L
F
E
V
A
N
Q
L
E
N
T
P
-------------------------------------------------------------------------------------
56
Fugue
49.14
19%
-61
- C1 -
-
1M2O
1
SAR1_YEAST
B:
[24-190]
---------------------------------------------------------------------------------------------------------------------------------------------------------------
G
K
L
L
F
L
-
G
L
D
N
A
G
K
T
T
L
L
H
M
L
K
N
D
-
R
L
A
-
T
L
Q
P
T
W
H
P
T
S
E
E
L
A
I
-----
G
N
I
K
F
T
T
F
D
L
G
G
-------------------
H
I
Q
-
A
R
-
R
L
W
K
D
Y
F
P
E
V
N
-
G
I
V
F
L
V
D
------
A
-
A
D
P
E
R
F
D
E
A
R
V
E
L
D
A
L
F
N
I
A
E
L
K
D
V
P
F
V
I
L
G
N
K
I
D
A
P
----
N
A
V
S
----
E
A
E
L
R
S
A
L
G
L
L
N
T
T
GIEG
Q
R
P
V
------
E
---
V
F
M
C
S
---
V
V
M
R
N
G
Y
L
E
A
F
Q
W
L
S
Q
Y
I
-----------------------------------------------------------------------------------------
61
Fugue
48.78
16%
-103
- C1 -
-
1PUI
-
ENGB_ECOLI
A:
[11-198]
-----------------------------------------------------------------------------------------------------------------------------------------------
F
V
M
S
A
P
D
I
R
H
L
P
S
D
T
G
I
E
V
A
F
A
-
G
R
S
N
A
G
K
S
S
A
L
N
T
L
T
N
Q
-
Q
L
-----
I
N
L
F
E
V
A
D
G
K
R
L
V
D
------------
L
P
G
Y
G
E
M
K
--
R
-------
K
---
W
Q
R
-
A
L
-
G
E
Y
L
E
K
R
Q
S
L
Q
-
G
L
V
V
L
M
D
I
R
H
P
-----
L
K
D
L
D
Q
Q
M
I
E
W
A
V
D
-------
S
N
I
A
V
L
V
L
L
T
K
A
D
K
L
----
A
S
G
A
----
R
K
A
Q
L
N
M
V
-
R
E
A
V
L
-----
A
F
N
------
G
D
V
Q
V
E
T
F
S
---
S
L
K
K
Q
G
V
D
K
L
R
Q
K
L
D
T
W
F
S
----------------------------------------------------------------------------------------
47
HHSearch
43.72
23%
-18
- C1 -
-
1WF3
3
ERA_THET8
A:
[7-221]
--------------------------------------------------------------------------------------------------------------------------------------------------------------
S
G
F
V
A
I
V
-
G
K
P
N
V
G
K
S
T
L
L
N
N
L
L
G
V
-
K
V
A
P
I
S
P
R
P
Q
T
T
R
K
R
L
R
G
I
L
T
E
G
--
R
R
Q
I
V
F
V
D
T
P
G
L
H
K
P
M
--
D
-------
A
L
--
G
E
F
-
M
D
-
Q
E
V
Y
E
A
L
A
D
V
N
-
A
V
V
W
V
V
D
L
R
H
P
P
----
T
P
E
D
-
E
L
V
A
R
A
L
K
P
L
--
V
---
G
K
V
P
I
L
L
V
G
N
K
L
D
A
A
K---
Y
P
E
E
A
---
M
K
A
Y
-
H
E
L
-
L
P
E
---------
A
------
E
---
P
R
M
L
S
---
A
L
D
E
R
Q
V
A
E
L
K
A
D
L
L
A
L
M
P
E
G
P
F
--------------
F
Y
P
E
--
D
Y
A
K
S
D
Q
T
F
G
E
W
V
A
E
I
L
R
E
E
A
M
K
R
L
W
H
E
V
P
Y
A
V
A
T
K
V
E
E
V
A
-----------------------
39
HHSearch
41.71
20%
-21
- C1 -
-
4NON
1
?
A:
[2-162]
---------------------------------------------------------------------------------------------------------------------------------------------------------------
T
E
I
A
L
I
-
G
N
P
N
S
G
K
T
S
L
F
N
L
I
T
G
H
-
N
Q
R
-
V
G
N
W
P
G
V
T
V
E
R
K
S
G
L
V
K
-
K
--
N
K
D
L
E
I
Q
D
L
P
G
I
Y
S
M
S
--
P
YS-----
P
---
E
E
K
-
V
A
-
R
D
Y
L
L
-
S
Q
R
A
D
-
S
I
L
N
V
V
D
A
T
N
L
----
E
R
N
---
L
Y
L
T
T
Q
L
I
E
-------
T
G
I
P
V
T
I
A
L
N
M
I
D
V
L
D
---
G
Q
G
K
----
K
I
N
V
-
D
K
L
-
S
Y
H
L
G
-------
V
------
P
---
V
V
A
T
S
---
S
L
K
Q
T
G
V
D
Q
V
V
K
K
A
A
H
T
T
T
S
---------------------------------------------------------------------------------------
44
HHSearch
41.39
19%
-43
- C1 -
-
3A1S
3
?
B:
[5-172]
--------------------------------------------------------------------------------------------------------------------------------------------------------------
M
V
K
V
A
L
A
-
G
C
P
N
V
G
K
T
S
L
F
N
A
L
T
G
T
-
K
Q
Y
-
V
A
N
W
P
G
V
T
V
E
K
K
E
G
V
F
T
Y
K
--
G
Y
T
I
N
L
I
D
L
P
G
T
Y
S
L
G
YS
S
-------
I
---
D
E
K
-
I
A
-
R
D
Y
L
L
K
-
G
D
A
D
-
L
V
I
L
V
A
D
S
V
N
P
E
------
Q
S
L
Y
L
L
L
E
I
L
E
M
--------
E
K
K
V
I
L
A
M
T
A
I
D
E
A
K
---
K
T
G
M
----
K
I
D
R
-
Y
E
L
-
Q
K
H
L
G
-------
I
------
P
---
V
V
F
T
S
---
S
V
T
G
E
G
L
E
E
L
K
E
K
I
V
E
Y
A
Q
K
N
T
I
------------------------------------------------------------------------------------
40
HHSearch
40.96
21%
-26
- C1 -
-
3B1V
1
?
A:
[3-164]
--------------------------------------------------------------------------------------------------------------------------------------------------------------
M
T
E
I
A
L
I
-
G
N
P
N
S
G
K
T
S
L
F
N
L
I
T
G
H
-
N
Q
R
-
V
G
N
W
P
G
V
T
V
E
R
K
S
G
L
V
K
-
K
--
N
K
D
L
E
I
Q
D
L
P
G
I
Y
S
M
S
--
P
-------
Y
S
P
-
E
A
K
-
V
A
-
R
D
Y
L
L
-
S
Q
R
A
D
-
S
I
L
N
V
V
D
A
T
N
L
----
E
R
N
---
L
Y
L
T
T
Q
L
I
E
-------
T
G
I
P
V
T
I
A
L
N
M
I
D
V
L
D
---
G
Q
G
K
----
K
I
N
V
-
D
K
L
-
S
Y
H
L
G
-------
V
------
P
---
V
V
A
T
S
---
A
L
K
Q
T
G
V
D
Q
V
V
K
K
A
A
H
T
T
T
S
---------------------------------------------------------------------------------------
10
PsiBlast_PDB
40.60
30%
-56
- C1 -
-
2E87
1
?
A:
[167-297]
--------------------------------------------------------------------------------------------------------------------------------------------------------------
I
P
T
V
V
I
A
-
G
H
P
N
V
G
K
S
T
L
L
K
A
L
T
T
A
-
K
P
E
-
I
A
S
Y
P
F
T
T
R
G
I
N
V
G
Q
F
E
-
D
-
G
Y
F
R
Y
Q
I
I
D
T
P
G
L
L
D
R
P
--
I
SERN
E
I
E
K
---
Q
A
I
-
L
A
-
L
R
Y
L
G
N
L
------
I
I
Y
I
F
D
P
S
E
H
C
G
F
--
P
L
E
E
Q
I
H
L
F
E
E
V
-----
H
G
E
F
K
D
L
P
F
L
V
V
I
N
K
I
D
V
A
----
D
E
E
N
-------------------------------------------------------------------------------------------------------------------------------------------------------
53
HHSearch
40.34
16%
-33
- C1 -
-
2GF0
1
DIRA1_HUMAN
B:
[7-173]
-------------------------------------------------------------------------------------------------------------------------------------------------------------
N
D
Y
R
V
V
V
F
-
G
A
G
G
V
G
K
S
S
L
V
L
R
F
V
K
G
-
T
F
R
-
D
T
Y
I
-
P
T
I
E
D
T
Y
R
Q
V
I
S
C
D
K
S
V
C
T
L
Q
I
T
D
T
T
G
S
H
Q
----------------
F
P
A
-
M
Q
-
R
L
S
I
S
---
K
G
H
-
A
F
I
L
V
F
S
V
T
S
K
----
Q
S
L
E
E
L
G
P
I
Y
K
L
I
V
Q
I
--
K
G
S
V
E
D
I
P
V
M
L
V
G
N
K
C
D
E
T
Q---
R
E
V
D
----
T
R
E
A
-
Q
A
V
-
A
Q
E
W
K
-------
C
------
A
---
F
M
E
T
S
---
A
K
M
N
Y
N
V
K
E
L
F
Q
E
L
L
T
L
E
T
R
R
N
-------------------------------------------------------------------------------------
13
PsiBlast_PDB
39.50
28%
-57
- C1 -
-
2QU8
1
?
A:
[32-176]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
I
I
L
S
-
G
A
P
N
V
G
K
S
S
F
M
N
I
V
S
R
A
-
N
V
D
-
V
Q
S
Y
-----
N
L
Y
V
G
H
F
D
H
K
-
L
N
K
-
Y
Q
I
I
D
T
P
G
L
L
D
R
A
--
F
-------
E
---
N
R
N
T
I
E
-
M
T
T
I
T
A
L
A
H
I
N
G
V
I
L
F
I
I
D
I
S
E
Q
C
G
L
-----
T
I
K
E
Q
I
N
L
F
Y
S
I
--
K
S
V
F
-
N
K
S
I
V
I
G
F
N
K
I
D
K
C
----
N
--
S
LS
I
D
N
K
L
L
I
K
Q
I
-
L
D
N
V
K
-------------------------------------------------------------------------------------------------------------------------------------
52
HHSearch
39.03
18%
-24
- C1 -
-
2KE5
1
RALB_HUMAN
A:
[3-169]
--------------------------------------------------------------------------------------------------------------------------------------------------------------
L
H
K
V
I
M
V
-
G
S
G
G
V
G
K
S
A
L
T
L
Q
F
M
Y
D
-
E
F
V
-
E
D
-
Y
E
P
T
K
A
D
S
Y
R
K
K
V
V
L
D
G
E
E
V
Q
I
D
I
L
D
T
A
G
L
E
D
Y
----------------
A
A
-
I
R
-
D
N
Y
F
R
---
S
G
E
-
G
F
L
L
V
F
S
I
T
E
H
----
E
S
F
T
A
T
A
E
F
R
E
Q
I
L
R
V
--
K
A
E
E
D
K
I
P
L
L
V
V
G
N
K
S
D
L
E
E---
R
R
Q
V
P---
V
E
E
A
-
R
S
K
-
A
E
E
W
G
-------
V
------
Q
---
Y
V
E
T
S
---
A
K
T
R
A
N
V
D
K
V
F
F
D
L
M
R
E
I
R
T
K
K
-------------------------------------------------------------------------------------
60
Fugue
38.71
22%
-29
- C1 -
-
2Q3F
1
RRAGD_HUMAN
A:
[3-181]
--------------------------------------------------------------------------------------------------------------------------------------------------------------
V
K
P
R
I
L
L
M
G
L
R
R
S
G
K
S
S
I
Q
K
V
V
F
H
K
M
S
P
N
-
E
T
L
F
L
E
S
T
N
K
I
C
R
E
D
V
S
N
S
-
S
F
V
N
F
Q
I
W
D
F
P
G
Q
I
D
F
F
--
D
-------
P
---
T
F
D
-
Y
E
M
I
-----
F
R
G
T
G
-
A
L
I
F
V
I
D
S
Q
--
D
D
Y
M
E
A
L
A
R
L
H
L
T
V
T
R
A
Y
K
V
--
N
T
---
D
I
N
F
E
V
F
I
H
K
V
D
G
L
SDD
H
K
I
E
T
----
Q
R
D
I
H
Q
R
A
-
N
D
D
L
A
-----
D
A
G
LEK
I
H
L
S
---
F
Y
L
T
S
IYD
H
S
I
F
E
A
F
S
K
V
V
Q
K
L
I
P
-------------------------------------------------------------------------------------------
37
HHSearch
38.65
21%
-4
* C1 *
-
3IEV
1
ERA_AQUAE
A:
[10-185]
--------------------------------------------------------------------------------------------------------------------------------------------------------------
V
G
Y
V
A
I
V
-
G
K
P
N
V
G
K
S
T
L
L
N
N
L
L
G
T
-
K
V
S
I
I
S
P
K
A
G
T
T
R
M
R
V
L
G
V
K
N
I
P
-
N
E
A
Q
I
I
F
L
D
T
P
G
I
Y
E
P
K
--
K
-------
S
D
V
L
G
H
S
-
M
V
-
E
I
A
K
Q
S
L
E
E
A
D
-
V
I
L
F
M
I
D
A
T
E
G
W
----
R
P
R
D
E
E
I
Y
Q
N
F
I
K
P
-------
L
N
K
P
V
I
V
V
I
N
K
I
D
K
I
G---
P
A
K
N
----
V
L
P
L
I
D
E
I
-
H
K
K
H
P
-----
E
L
T
------
E
---
I
V
P
I
S
---
A
L
K
G
A
N
L
D
E
L
V
K
T
I
L
K
Y
L
P
E
G
E
P
------------------------------------------------------------------------------------