@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VTY7: (2017-12-15 )
MHLLQPQPEVNTSLLVCTHSTHQNPLLPDVVQLSPWPSSKLESEQVDWLILHFNHWFSHHNVTLVRGEFEPEYFPANEHEPAKIQFAHGFFNSALHEISHWTIAGAKRRLLPDLGYWYAPDGRTKEQQDLFEQVEIKPQAIEWLFAQSFGRKFRVSLDNLTGDGGDGRKFKDNVYAQVQRYFSGEAKLPADAARFIECICQCTRAGAALQLNEFKRELLD
Atome Classification :
(20 SA)
--------------------------------------------------------------------------.........10........20...--.....30.-----------.......40......---..50.......--------.60.....--....70.------------..-------------.....-80-.......-.----90.-----------.-----------..-....100-..-.....110.......120.....---..130.-......140....----------------...150------.-------........--160......-.170..----.....180.......190.......200.-......210.......220----
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
--------------------------------------------------------------------------MHLLQPQPEVN
T
S
L
L
V
C
THSTHQN--PLLP
D
V
VQ-----------LSPWPSSKLESEQV
D
---
W
L
I
L
HFNHWFS--------HH-
N
V
T
L
V
--RGEFEPE------------YF-------------PANEH-EP-
A
K
I
Q
F
A
H
-
G
----
F
F
N
-----------
S
-----------
A
L
-
H
E
IS
H
W
T
-IA-G
A
K
RRLLPDLG
Y
W
YAPDGRT
K
E
Q
---
Q
D
L
F
E
Q
-VEI
K
P
Q
A
I
E
W
L
F
A
----------------
Q
S
FG--------
R
-------
K
F
R
V
S
LDN--LTGDGGDGR-
K
F
K
D
N
V
----
Y
A
Q
V
Q
R
Y
FSGEAKL
P
A
D
A
A
R
F
I
E
C
I
C
Q
C
T
-RAG
A
A
L
Q
L
N
E
F
K
R
E
LLD------
12
HHSearch
79.29
44%
-57
- C9 -
-
3WTR
-
?
A:
[3-177]
--------------------------------------------------------------------------------------------------------------------------------
S
T
H
H
Y
E
---
Q
L
I
E
I
F
N
S
C
F
A
D-------
E
F
-
N
T
R
L
I
--
K
G
D
D
E
P
I
------------
Y
L
-------------
P
A
D
A
E
V
P
Y
-
N
R
I
V
F
A
H
-
G
----
F
Y
A
-----------
S
-----------
A
I
-
H
E
I
S
H
W
C
-
I
A
-----------------------------
Q
F
E
D
-
V
E
V
K
P
Q
A
L
D
W
L
F
C
----------------
V
A
A
G
--------
Y
-------
P
F
N
V
S
------------
R
V
-
V
F
Q
R
R
V
----
H
A
Q
V
M
D
Y
L
--
A
N
G
I
P
E
R
P
A
R
F
I
K
A
L
Q
N
Y
Y
-
Y
T
P
E
-
L
T
A
E
Q
F
P
W
----------
32
Fugue
76.86
40%
-46
- C9 -
-
4PDN
-
?
A:
[3-179]
--------------------------------------------------------------------------------------------------------------------------------
S
T
H
H
Y
E
---
Q
L
I
E
I
F
N
S
C
F
A
D-------
E
F
-
N
T
R
L
I
--
K
G
D
D
E
P
I
------------
Y
L
-------------
P
A
D
A
E
-
V
P
Y
N
R
I
V
F
A
H
-
G
----
F
Y
A
-----------
S
-----------
A
I
-
H
E
I
S
H
W
C
-
I
A
-
Q
----------------------------
F
E
D
-
V
E
V
K
P
Q
A
L
D
W
L
F
C
----------------
V
A
A
G
--------
Y
-------
P
F
--------------
N
R
V
-
V
F
Q
R
R
V
----
H
A
Q
V
M
D
Y
L
--
A
N
G
I
P
E
R
P
A
R
F
I
K
A
L
Q
N
Y
Y
-
Y
T
-
P
E
L
T
A
E
Q
F
P
W
P
E
--------
13
HHSearch
76.52
44%
-52
- C9 -
-
4PDN
-
?
A:
[3-177]
--------------------------------------------------------------------------------------------------------------------------------
S
T
H
H
Y
E
---
Q
L
I
E
I
F
N
S
C
F
A
D-------
E
F
-
N
T
R
L
I
--
K
G
D
D
E
P
I
------------
Y
L
-------------
P
A
D
A
E
V
P
Y
-
N
R
I
V
F
A
H
-
G
----
F
Y
A
-----------
S
-----------
A
I
-
H
E
I
S
H
W
C
-
I
A
-----------------------------
Q
F
E
D
-
V
E
V
K
P
Q
A
L
D
W
L
F
C
----------------
V
A
A
G
--------
Y
-------
P
F
N
--------------
R
V
-
V
F
Q
R
R
V
----
H
A
Q
V
M
D
Y
L
--
A
N
G
I
P
E
R
P
A
R
F
I
K
A
L
Q
N
Y
Y
-
Y
T
P
E
-
L
T
A
E
Q
F
P
W
----------
2
PsiBlast_PDB
72.73
49%
-94
- C9 -
-
3WTR
-
?
A:
[10-161]
------------------------------------------------------------------------------------------------------------------------------------------
L
I
E
I
F
N
S
C
F
A
--------
D
E
F
N
T
R
L
I
--
K
G
D
D
E
P
I
------------
Y
L
-------------
P
A
D
A
E
-
V
P
Y
N
R
I
V
F
A
H
-
G
----
F
Y
A
-----------
S
-----------
A
I
-
H
E
I
S
H
W
C
-
I
A
-----------------------------
Q
F
E
D
-
V
E
V
K
P
Q
A
L
D
W
L
F
C
----------------
V
A
A
G
--------
Y
-------
P
F
N
V
S
-------------
R
V
V
F
Q
R
R
V
----
H
A
Q
V
M
D
Y
L
A
N
--
G
I
P
E
R
P
A
R
F
I
K
A
L
----------------------------
1
PsiBlast_PDB
71.58
49%
-88
- C9 -
-
4PDN
-
?
A:
[10-161]
------------------------------------------------------------------------------------------------------------------------------------------
L
I
E
I
F
N
S
C
F
A
--------
D
E
F
N
T
R
L
I
--
K
G
D
D
E
P
I
------------
Y
L
-------------
P
A
D
A
E
-
V
P
Y
N
R
I
V
F
A
H
-
G
----
F
Y
A
-----------
S
-----------
A
I
-
H
E
I
S
H
W
C
-
I
A
-----------------------------
Q
F
E
D
-
V
E
V
K
P
Q
A
L
D
W
L
F
C
----------------
V
A
A
G
--------
Y
-------
P
F
N
---------------
R
V
V
F
Q
R
R
V
----
H
A
Q
V
M
D
Y
L
A
N
--
G
I
P
E
R
P
A
R
F
I
K
A
L
----------------------------
37
Fugue
48.47
19%
-9
- C7 -
-
5E4B
1
?
A:
[34-209]
-------------------------------------------------------------------------E
Q
F
Q
L
R
G
V
L
W
G
K
A
Y
S
W
K
I
T
G
T
T
I
D
K
V
W
S
I
V
G
D
Y
V
R
-----------
V
D
N
W
V
S
S
V
V
K
S
S
H
V
V
---
S
---------
G
--------
E
A
-
N
Q
T
G
C
--
V
R
R
F
V
C
--------------
Y
-------------
P
A
S
E
G
-
E
S
-
E
T
V
D
Y
S
E
L
I
----
H
M
N
-----------
A
-----------
A
A
-
H
Q
Y
M
Y
M
I
-
V
G
-
G
N
I
T
G
---------------------------------------
F
S
----------------
L
M
K
N
--------
Y
-------
V
S
N
I
S
L
S
S
--
L
P
E
E
D
G
G
G
V
-
I
F
Y
W
S
F
----
T
A
E
P
A
S
N
L
T
E
Q
K
C
I
E
I
V
F
P
L
Y
T
T
A
L
K
D
L
C
-
T
H
L
S
---
I
P
E
S
S
V
T
L
L
D
D-----
5
PsiBlast_PDB
44.39
23%
16
- C9 -
-
4KRX
1
AES_ECOLI
A:
[26-154]
---------------------------------------------------------------------------------------
L
I
S
A
E
M
K
T
V
V
N
--
T
L
Q
P
D
--------------
L
P
P
W
P
A
T
G
T
I
A
E
Q
R
Q
---
Y
Y
T
L
E
R
R
F
W
N
A
GAPE
M
A
T
R
A
Y
-
M
V
P
T
K
--
Y
G
Q
V
E
T
R
------------
L
F
-------------
C
P
Q
P
D
-
S
P
-
A
T
L
F
Y
L
H
-
G
GGFI
L
G
N
-----------
L
-----------
D
T
-
H
D
R
I
M
R
L
-
L
A
-
S
Y
S
Q
C
T
V
I
G
I
D
Y
T
L
S
P
E
A
R
F
-----------------
P
Q
A
I
E
E
I
V
A
-----------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
43.26
23%
21
- C9 -
-
4KRY
1
AES_ECOLI
A:
[26-152]
---------------------------------------------------------------------------------------
L
I
S
A
E
M
K
T
V
V
N
--
T
L
Q
P
D
--------------
L
P
P
W
P
A
T
G
T
I
A
E
Q
R
Q
---
Y
Y
T
L
E
R
R
F
W
N
A
GAPEMA
T
R
A
Y
-
M
V
P
T
K
--
Y
G
Q
V
E
T
R
------------
L
F
-------------
C
P
Q
P
D
-
S
P
-
A
T
L
F
Y
L
H
-
G
GGFI
L
G
N
-----------
L
-----------
D
T
-
H
D
R
I
M
R
L
-
L
A
-
S
Y
S
Q
C
T
V
I
G
I
D
Y
T
L
S
P
E
A
R
F
-----------------
P
Q
A
I
E
E
I
V
A
-----------------------------------------------------------------------------------------------------------------------
30
HHSearch
41.51
40%
-205
- C3 -
-
5GNF
-
?
A:
[90-99]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
F
A
D
W
G
W
W
Y
R
------------------------------------------------------------------------------------------------------------------------------------------------------
31
HHSearch
41.40
40%
-196
- C1 -
-
5GNF
-
?
B:
[90-99]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
F
A
D
W
G
W
W
Y
R
------------------------------------------------------------------------------------------------------------------------------------------------------
38
Fugue
38.39
16%
-108
- C6 -
-
5MUU
-
CAPSD_BPPH6
D:
[1-148]
---------------------------------------------------------------------------------------
M
L
L
P
V
V
A
R
A
A
V
--
P
A
I
E
S
A
I
A
-----------
A
T
P
G
L
V
S
R
I
A
A
A
-------------------------------
I
G
--
S
K
V
S
P
S
A
------------
I
L
-------------
A
A
V
K
S
-
N
P
-
V
V
A
G
L
T
L
-
A
----
Q
I
G
-----------
S
--------------------
T
-
G
Y
-
D
A
Y
Q
Q
L
L
E
N
----------
H
P
E
V
---
A
E
M
L
K
D
-
L
S
F
K
A
D
E
I
Q
P
D
F
I
----------------
G
N
L
G
--------
Q
-------
Y
-------------------
R
E
E
L
E
L
----
V
E
D
A
A
R
F
V
G
G
M
S
N
L
I
R
L
R
Q
A
L
E
L
D
I
---
K
-
Y
Y
G
L
K
M
Q
L
N
D
M
G
Y
R
---------
39
Fugue
37.74
14%
27
* C10 *
-
3Q8D
2
RECO_ECOLI
A:
[2-232]
---------------------------------------------------------------------EG
W
Q
R
A
F
V
L
H
S
R
P
W
S
E
T
S
L
M
L
D
V
F
T
E
E
S
G
---
R
V
R
L
V
A
K
-----------
G
A
R
S
K
R
S
T
L
K
G
A
L
Q
P
---
F
T
P
L
L
L
R
F
G
G
R
--------
G
E
-
V
K
T
L
R
--
S
A
E
A
V
S
L
------------
A
L
-------------
P
L
S
G
I
-
T
L
-
Y
S
G
L
Y
I
N
-
E
----
L
L
S
-----------
R
-----------
V
L
E
Y
E
T
R
F
S
E
-
L
F
-
F
D
Y
L
H
C
I
Q
S
L
A
---
G
V
T
G
T
P
E
P
A
---
L
R
R
F
E
L
-
A
L
L
G
H
L
G
Y
G
V
N
F
T
----------------
H
C
A
G
SG
E
P
V
D
DT
M
-------
T
Y
R
Y
R
E
E
K
GF
I
A
S
V
V
I
D
N
K
-
T
F
T
G
R
Q
----
L
K
A
L
N
A
R
E
F
P
D
A
D
T
L
R
A
A
K
R
F
T
R
M
A
L
K
P
Y
-
L
G
G
K
P
L
K
S
R
E
L
F
R
Q
F
M
-------
40
Fugue
34.33
13%
5
- C10 -
-
3AQB
-
HEXB_MICLU
B:
[5-325]
S
Y
K
A
F
L
N
P
Y
I
I
E
V
E
K
R
L
Y
E
C
I
QSDS
E
T
I
N
K
A
A
H
H
I
L
S
SGGKR
V
R
P
M
F
V
L
L
S
G
F
L
N
D
T
Q
K
D
D
L
I
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A
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L
E
L
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M
A
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D
D
Y
I
D
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M
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N
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S
V
H
I
A
--
F
D
K
D
T
A
I
R
-----------
T
G
H
F
L
L
A
R
A
L
Q
N
I
A
T
---
I
N
N
S
K
F
H
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I
F
S
--------
K
T
-
I
L
E
V
C
--
F
G
E
F
D
Q
M
A
D
RFNYPVS
F
T
A
Y
L
-------------
R
R
I
N
R
-
K
T
-
A
I
L
I
E
A
S
-
C
----
H
L
G
-----------
A
L
S
S
QLD
E
Q
---
S
T
-
Y
H
I
K
Q
F
G
-
H
C
-
I
G
M
S
Y
Q
I
I
D
D
I
L
D
Y
T
S
D
E
A
T
L
G
K
PVG
S
D
I
R
N
G
-
H
I
T
Y
P
L
M
A
A
I
A
N
L
----------------
K
E
Q
D
--------
D
D------
K
L
E
A
V
V
K
H
--
L
T
S
T
S
D
D
E
V
-
Y
Q
Y
I
V
S
----
Q
V
K
Q
Y
G
I
E
P
A
E
L
L
S
R
K
Y
G
D
K
A
K
Y
H
L
S
Q
L
Q
-
D
S
N
I
K
D
Y
L
E
E
I
H
E
K
M
L
K
RVY---
23
HHSearch
31.72
15%
-166
- C9 -
-
1VJQ
-
?
A:
[27-73]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
F
D
W
Q
N
P
P
T
E
P
G
--------
Q
P
V
V
-
I
L
I
P
S
D
M
V
E
W
F
L
E
M
L
--------------
K
A
K
G
--------
I
-------
P
F
T
V
Y
V
E
E
--
G
G
S
----------------------------------------------------------------------
3
PsiBlast_PDB
30.79
36%
-186
- C9 -
-
4NES
2
WECB_METJA
A:
[11-44]
-------------------------------------------------------------------------------------------------------
P
E
I
I
K
-----------
L
S
P
I
I
R
A
-
L
E
K
T
N
I
D
---
W
H
I
I
H
T
N
Q
H
Y
S
--------
E
N
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
29.17
15%
-91
- C9 -
-
1OTG
-
HPCD_ECOLX
B:
[34-112]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
P
L
-
A
----
G
I
R
-----------
S
-----------
R
V
-
H
W
V
D
T
W
Q
-
M
A
-
D
G
Q
H
D
Y
A
F
V
H
M
T
L
K
I
G
A
G
R
S
L
E
S
---
R
Q
Q
A
G
E
-------
M
L
F
E
L
I
K
----------------
T
H
F
A
--------
A
LMESRLL
A
L
S
F
E
I
E
E
--
L
H
P
T
---------------------------------------------------------------------
6
PsiBlast_PDB
28.89
34%
-
- C9 -
-
5FBY
-
?
A:
[2017-2092]
-----------------------------------------------------------------------------------------------
H
H
A
--
P
L
S
G
G
T
Y
I
-----------
L
N
P
--
S
S
D
L
L
S
T
Q
K
T
---
F
E
S
L
F
S
T
H
L
H
S
--------
P
N
-
S
W
T
R
I
I
S
R
P
P
T
E
P
E
------------
F
L
-------------
S
A
L
T
H
-
S
P
-
I
L
L
Y
F
G
H
-
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
41
Fugue
28.04
8%
12
- C8 -
-
2P2S
4
?
A:
[4-336]
--------------------K
I
R
F
A
A
I
G
LAHN
H
I
Y
D
M
C
Q
Q
L
I
D
A
G
A
E
L
A
G
V
F
E
SDSDNR
A
K
F
T
S
L
FPS
V
P
F
A
AS
A
E
Q
L
I
T
D
A
S
I
D
L
I
A
C
A
V
I
P
C
D
R
A
E
--
L
A
L
R
T
L
D
A
G
K
D
F
F
T
A
K
PPL
T
T
L
E
Q
L
D
A
V
Q
R
R
V
A
E
T
G
R
K
F
A
V
Y
F
N
E
R
I
N
--------
V
D
-
S
A
L
F
A
--
G
E
L
V
Q
R
G
------------
E
I
GRVI
Q
T
M
G
V
G
P
H
R
E
R
G
A
R
-
P
D
-
W
F
Y
Q
K
R
Q
-
Y
GGI-
L
C
D
-----------
I
-----------
G
I
-
H
Q
I
E
Q
F
L
-
Y
F
T
G
N
T
N
A
R
V
V
T
S
Q
T
A
N
Y
H
H
P
H
H
P
E
F
---
E
D
F
G
D
A
M
L
L
G
D
N
G
A
T
G
Y
F
R
C
D
WFTPDGLSVWGD
G
R
L
T
I
L
G
--------
T
-------
E
G
Y
I
E
I
R
K
--
Y
V
D
L
T
R
G
E
S
-
N
V
V
Y
L
V
N
GK
G
E
Q
R
F
T
P
A
G
S
V
E
R
A
F
F
P
D
F
L
R
D
C
R
E
R
T
E
N
A
M
S
Q
S
H
I
F
K
A
T
E
L
S
I
L
A
Q
Q
A
ANKIA
17
HHSearch
27.45
39%
-159
- C9 -
-
2X3B
-
?
A:
[267-309]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
-
Y
K
V
Y
L
C
K
-
S
----
F
W
T
-----------
A
PVTGSDS
R
A
G
T
I
V
-
H
A
L
S
H
F
N
V
V
A
-
G
T
-----
D
D
L
G
Y
---------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
25.04
28%
-115
- C9 -
-
1GE5
-
A:
[91-133]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
-
G
T
V
Y
L
C
G
-
A
----
F
W
K
APTTGTDS
Q
A
G
T
-----------
L
V
-
H
E
S
S
H
F
T
-
R
N
-
G
G
----
T
K
D
Y
A
Y
---------------------------------------------------------------------------------------------------------------------------------------------------------