@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VU09: (2017-12-16 )
MFDTLTERLTQSLRNVTGSGQLTEDNIKDTLREVRMALLEADVALPVTREFIAKVKEEALGQEVMTQLSPGQAFVKIVYDELTKMMGEANETLDLSAKPPVVVLLAGLQGAGKTTTAAKLARFLKERQKKKVMTVSADVYRPAAIKQLETVSAEVGAGFIPSDPSEKPIDIVNRAIEQAKIQFADVLIVDTAGRLHVDEDMMDEIKELHAAVKPTETLFVVDAMTGQDAANTAKAFNDALALTGVILTKTDGDARGGAALSVRAITGKPIKFLGMGEKLDALEPFHPDRVAQRILGMGDVLSLVEEVERKIDKEKAEKMAKKLQKGGSFNFEDMLMQFEQMKKMGGMMGFLDKLPGMSSAGIQQAIEQANPEKQVKKMEAIIQSMTIKERRNPDLMNPSRKKRIAAGCGMDVAEVNKLIKQQAQMAKMMKKFANPSGMSKMMRSLGNMQKQFGGGGGMGPLFGNNDQKK
Atome Classification :
(48 SA)
.........10........-----------20........30........40........50........60........70........80........---90.-----.----..------....100-----.......110.......120.......130.......140.......150.......160.....-..170.......180.......190.......200.........210------.------......220.......230.......240..-.....250.......260.......270.......280.......290.......300...-----....310-.......320....-...330.......340.......350.......360.......370........380.......390....-----...400.......410-.........420.......430.......440.......450.......460.......-----------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MF
D
T
L
T
E
R
L
T
Q
S
L
R
NVTGS-----------GQL
T
E
D
N
I
K
D
T
L
R
E
V
R
M
A
L
L
EADVAL
P
V
T
R
E
F
I
A
K
V
K
E
E
AL
G
Q
E
V
M
T
QLSP
G
Q
A
F
V
K
I
V
Y
D
E
L
T
K
M
MGEA---NE
T
-----
L
----DL------SAKP
P
V
V
-----
V
L
L
AGLQGAGKT
T
T
A
A
K
L
A
R
F
L
K
E
R
Q
KK
K
V
M
T
VSADVYR
P
A
A
I
K
Q
L
E
T
V
S
A
EVGAGFIPSDPSEK-
P
I
D
I
V
N
R
A
I
E
Q
A
K
I
Q
F
A
D
V
L
I
V
DTAGRLHV
D
E
D
--
M
M
D
E
I
K
E
L
H
A
AV------K------PT
E
T
L
F
V
V
DAMTGQDA
A
N
T
A
K
A
F
N
D
A
L
A
L
T
G
-
V
I
L
T
KTDGDARG
G
A
A
L
S
V
R
AITGK
P
I
K
F
L
GMGEKLDALEPF
H
P
D
R
V
A
Q
R
I
LG
M
G
D
V
L
S
L
V
E
-----
E
V
E
R
K
I
D
-
K
E
K
A
E
K
M
A
K
K
L
Q
KG-GSF
N
F
E
D
M
L
M
Q
F
E
Q
M
K
K
MG
G
M
M
G
F
L
D
KLPGM
S
S
A
G
I
Q
Q
A
I
E
QA
N
-
P
E
K
Q
V
K
K
M
E
A
I
I
Q
S
M
T
I
KERRNPDLM-----
N
P
S
R
K
K
R
IAAGCGM---
D
V
A
E
V
N
K
L
I
K
Q
Q
A
Q
M
A
K
M
M
K
K
FA
N
P
S
G
M
S
K
M
M
R
S
L
G
N
M
Q
K
Q
FGGGGGMGPLFGNNDQKK-----------------
1
PsiBlast_PDB
90.38
66%
-96
- C5 -
-
2XXA
2
SRP54_ECOLI
A:
[4-425]
---
N
L
T
D
R
L
S
R
T
L
R
N
I
S
G
R
-----------
G
R
L
T
E
D
N
V
K
D
T
L
R
E
V
R
M
A
L
L
E
A
D
V
A
L
P
V
V
R
E
F
I
N
R
V
K
E
K
A
V
G
H
E
V
N
K
S
L
T
P
G
Q
E
F
V
K
I
V
R
N
E
L
V
A
A
M
G
E
E
---
N
Q
T
-----
L
----
N
L
------
A
A
Q
P
P
A
V
-----
V
L
M
A
G
L
Q
G
A
G
K
T
T
S
V
G
K
L
G
K
F
L
R
E
K
H
K
K
K
V
L
V
V
S
A
D
V
Y
R
P
A
A
I
K
Q
L
E
T
L
A
E
Q
V
G
V
D
F
F
P
S
D
V
G
Q
K
-
P
V
D
I
V
N
A
A
L
K
E
A
K
L
K
F
Y
D
V
L
L
V
D
T
A
G
R
L
H
V
D
E
A
--
M
M
D
E
I
K
Q
V
H
A
S
I
------
N
------
P
V
E
T
L
F
V
V
D
A
M
T
G
Q
D
A
A
N
T
A
K
A
F
N
E
A
L
P
L
T
G
-
V
V
L
T
K
V
D
G
D
A
R
G
G
A
A
L
S
I
R
H
I
T
G
K
P
I
K
F
L
G
V
G
E
K
T
E
A
L
E
P
F
H
P
D
R
I
A
S
R
I
L
G
M
G
D
V
L
S
L
I
E
-----
D
I
E
S
K
V
D
-
R
A
Q
A
E
K
L
A
S
K
L
K
K
G
-
D
G
F
D
L
N
D
F
L
E
Q
L
R
Q
M
K
N
M
G
G
M
A
S
L
M
G
K
------------------
D
D
K
V
L
V
R
M
E
A
I
I
N
S
M
T
M
K
E
R
A
K
P
E
I
I
-----
K
G
S
R
K
R
R
I
A
A
G
S
G
M
---
Q
V
Q
D
V
N
R
L
L
K
Q
F
D
D
M
Q
R
-----------------------------------------------------------
21
PsiBlast_CBE
90.02
66%
-104
- C5 -
-
2XXA
2
SRP54_ECOLI
C:
[7-425]
------
D
R
L
S
R
T
L
R
N
I
S
G
R
-----------
G
R
L
T
E
D
N
V
K
D
T
L
R
E
V
R
M
A
L
L
E
A
D
V
A
L
P
V
V
R
E
F
I
N
R
V
K
E
K
A
V
G
H
E
V
N
K
S
L
T
P
G
Q
E
F
V
K
I
V
R
N
E
L
V
A
A
M
G
E
E
---
N
Q
T
-----
L
----
N
L
------
A
A
Q
P
P
A
V
-----
V
L
M
A
G
L
Q
G
A
G
K
T
T
S
V
G
K
L
G
K
F
L
R
E
K
H
K
K
K
V
L
V
V
S
A
D
V
Y
R
P
A
A
I
K
Q
L
E
T
L
A
E
Q
V
G
V
D
F
F
P
S
D
V
G
Q
K
-
P
V
D
I
V
N
A
A
L
K
E
A
K
L
K
F
Y
D
V
L
L
V
D
T
A
G
R
L
H
V
D
E
A
--
M
M
D
E
I
K
Q
V
H
A
S
I
------
N
------
P
V
E
T
L
F
V
V
D
A
M
T
G
Q
D
A
A
N
T
A
K
A
F
N
E
A
L
P
L
T
G
-
V
V
L
T
K
V
D
G
D
A
R
G
G
A
A
L
S
I
R
H
I
T
G
K
P
I
K
F
L
G
V
G
E
K
T
E
A
L
E
P
F
H
P
D
R
I
A
S
R
I
L
G
M
G
D
V
L
S
L
I
E
-----
D
I
E
S
K
V
D
-
R
A
Q
A
E
K
L
A
S
K
L
K
K
G
-
D
G
F
D
L
N
D
F
L
E
Q
L
R
Q
M
K
N
M
G
G
M
A
S
L
M
G
-------------------
D
D
K
V
L
V
R
M
E
A
I
I
N
S
M
T
M
K
E
R
A
K
P
E
I
I
-----
K
G
S
R
K
R
R
I
A
A
G
S
G
M
---
Q
V
Q
D
V
N
R
L
L
K
Q
F
D
D
M
Q
R
-----------------------------------------------------------
107
HHSearch
85.99
73%
-107
- C5 -
-
4C7O
3
SRP54_ECOLI
C:
[2-298]
-
F
D
N
L
T
D
R
L
S
R
T
L
R
N
I
S
G
R
-----------
G
R
L
T
E
D
N
V
K
D
T
L
R
E
V
R
M
A
L
L
E
A
D
V
A
L
P
V
V
R
E
F
I
N
R
V
K
E
K
A
V
G
H
E
V
N
K
S
L
T
P
G
Q
E
F
V
K
I
V
R
N
E
L
V
A
A
M
G
E
E
---
N
Q
T
-----
L
----
N
L
------
A
A
Q
P
P
A
V
-----
V
L
M
A
G
L
Q
G
A
G
K
T
T
S
V
G
K
L
G
K
F
L
R
E
K
H
K
K
K
V
L
V
V
S
A
D
V
Y
R
P
A
A
I
K
Q
L
E
T
L
A
E
Q
V
G
V
D
F
F
P
S
D
V
G
Q
K
-
P
V
D
I
V
N
A
A
L
K
E
A
K
L
K
F
Y
D
V
L
L
V
D
T
A
G
R
L
H
V
D
E
A
--
M
M
D
E
I
K
Q
V
H
A
S
I
------
N
------
P
V
E
T
L
F
V
V
D
A
M
T
G
Q
D
A
A
N
T
A
K
A
F
N
E
A
L
P
L
T
G
-
V
V
L
T
K
V
D
G
D
A
R
G
G
A
A
L
S
I
R
H
I
T
G
K
P
I
K
F
L
G
V
G
E
K
T
E
A
L
E
P
F
H
P
D
R
I
A
S
R
I
L
G
M
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
85.99
73%
-107
- C5 -
-
4C7O
3
SRP54_ECOLI
C:
[2-298]
-
F
D
N
L
T
D
R
L
S
R
T
L
R
N
I
S
G
R
-----------
G
R
L
T
E
D
N
V
K
D
T
L
R
E
V
R
M
A
L
L
E
A
D
V
A
L
P
V
V
R
E
F
I
N
R
V
K
E
K
A
V
G
H
E
V
N
K
S
L
T
P
G
Q
E
F
V
K
I
V
R
N
E
L
V
A
A
M
G
E
E
---
N
Q
T
-----
L
----
N
L
------
A
A
Q
P
P
A
V
-----
V
L
M
A
G
L
Q
G
A
G
K
T
T
S
V
G
K
L
G
K
F
L
R
E
K
H
K
K
K
V
L
V
V
S
A
D
V
Y
R
P
A
A
I
K
Q
L
E
T
L
A
E
Q
V
G
V
D
F
F
P
S
D
V
G
Q
K
-
P
V
D
I
V
N
A
A
L
K
E
A
K
L
K
F
Y
D
V
L
L
V
D
T
A
G
R
L
H
V
D
E
A
--
M
M
D
E
I
K
Q
V
H
A
S
I
------
N
------
P
V
E
T
L
F
V
V
D
A
M
T
G
Q
D
A
A
N
T
A
K
A
F
N
E
A
L
P
L
T
G
-
V
V
L
T
K
V
D
G
D
A
R
G
G
A
A
L
S
I
R
H
I
T
G
K
P
I
K
F
L
G
V
G
E
K
T
E
A
L
E
P
F
H
P
D
R
I
A
S
R
I
L
G
M
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
83.55
73%
-104
- C5 -
-
4C7O
2
SRP54_ECOLI
A:
[4-296]
---
N
L
T
D
R
L
S
R
T
L
R
N
I
S
G
R
-----------
G
R
L
T
E
D
N
V
K
D
T
L
R
E
V
R
M
A
L
L
E
A
D
V
A
L
P
V
V
R
E
F
I
N
R
V
K
E
K
A
V
G
H
E
V
N
K
S
L
T
P
G
Q
E
F
V
K
I
V
R
N
E
L
V
A
A
M
G
E
E
---
N
Q
T
-----
L
----
N
L
------
A
A
Q
P
P
A
V
-----
V
L
M
A
G
L
Q
G
A
G
K
T
T
S
V
G
K
L
G
K
F
L
R
E
K
H
K
K
K
V
L
V
V
S
A
D
V
Y
R
P
A
A
I
K
Q
L
E
T
L
A
E
Q
V
G
V
D
F
F
P
S
D
V
G
Q
K
-
P
V
D
I
V
N
A
A
L
K
E
A
K
L
K
F
Y
D
V
L
L
V
D
T
A
G
R
L
H
V
D
E
A
--
M
M
D
E
I
K
Q
V
H
A
S
I
------
N
------
P
V
E
T
L
F
V
V
D
A
M
T
G
Q
D
A
A
N
T
A
K
A
F
N
E
A
L
P
L
T
G
-
V
V
L
T
K
V
D
G
D
A
R
G
G
A
A
L
S
I
R
H
I
T
G
K
P
I
K
F
L
G
V
G
E
K
T
E
A
L
E
P
F
H
P
D
R
I
A
S
R
I
L
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
119
HHSearch
74.59
51%
-118
- C5 -
-
5L3R
2
SR54C_ARATH
C:
[27-300]
-------------------------------
V
L
T
K
D
N
I
A
E
P
M
R
D
I
R
R
A
L
L
E
A
D
V
S
L
P
V
V
R
R
F
V
Q
S
V
S
D
Q
A
V
G
M
G
-----
K
P
D
Q
Q
L
V
K
I
V
H
D
E
L
V
K
L
M
G
G
E
---
V
S
E
-----
L
----
Q
F
------
A
K
S
G
P
T
V
-----
I
L
L
A
G
L
Q
G
V
G
K
T
T
V
C
A
K
L
A
C
Y
L
K
K
Q
-
G
K
S
C
M
L
I
A
G
D
V
Y
R
P
A
A
I
D
Q
L
V
I
L
G
E
Q
V
G
V
P
V
Y
T
A
G
T
D
V
K
-
P
A
D
I
A
K
Q
G
L
K
E
A
K
K
N
N
V
D
V
V
I
M
D
T
A
G
R
L
Q
I
D
K
G
--
M
M
D
E
L
K
D
V
K
K
F
L
------
N
------
P
T
E
V
L
L
V
V
D
A
M
T
G
Q
E
A
A
A
L
V
T
T
F
N
V
E
I
G
I
T
G
-
A
I
L
T
K
L
D
G
D
S
R
G
G
A
A
L
S
V
K
E
V
S
G
K
P
I
K
L
V
G
R
G
E
R
M
E
D
L
E
P
F
Y
P
D
R
M
A
G
R
I
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
PsiBlast_CBE
74.05
50%
-119
- C5 -
-
5L3R
2
SR54C_ARATH
C:
[27-300]
-------------------------------
V
L
T
K
D
N
I
A
E
P
M
R
D
I
R
R
A
L
L
E
A
D
V
S
L
P
V
V
R
R
F
V
Q
S
V
S
D
Q
A
V
G
M
G
-----
K
P
D
Q
Q
L
V
K
I
V
H
D
E
L
V
K
L
M
G
G
E
---
V
S
E
-----
L
----
Q
F
------
A
K
S
G
P
T
V
-----
I
L
L
A
G
L
Q
G
V
G
K
T
T
V
C
A
K
L
A
C
Y
L
K
-
K
Q
G
K
S
C
M
L
I
A
G
D
V
Y
R
P
A
A
I
D
Q
L
V
I
L
G
E
Q
V
G
V
P
V
Y
T
A
G
T
D
V
K
-
P
A
D
I
A
K
Q
G
L
K
E
A
K
K
N
N
V
D
V
V
I
M
D
T
A
G
R
L
Q
I
D
K
G
--
M
M
D
E
L
K
D
V
K
K
F
L
------
N
------
P
T
E
V
L
L
V
V
D
A
M
T
G
Q
E
A
A
A
L
V
T
T
F
N
V
E
I
G
I
T
G
-
A
I
L
T
K
L
D
G
D
S
R
G
G
A
A
L
S
V
K
E
V
S
G
K
P
I
K
L
V
G
R
G
E
R
M
E
D
L
E
P
F
Y
P
D
R
M
A
G
R
I
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
73.16
50%
-120
- C5 -
-
5L3R
2
SR54C_ARATH
A:
[30-301]
----------------------------------
K
D
N
I
A
E
P
M
R
D
I
R
R
A
L
L
E
A
D
V
S
L
P
V
V
R
R
F
V
Q
S
V
S
D
Q
A
V
G
M
G
-----
K
P
D
Q
Q
L
V
K
I
V
H
D
E
L
V
K
L
M
G
G
E
---
V
S
E
-----
L
----
Q
F
------
A
K
S
G
P
T
V
-----
I
L
L
A
G
L
Q
G
V
G
K
T
T
V
C
A
K
L
A
C
Y
L
K
-
K
Q
G
K
S
C
M
L
I
A
G
D
V
Y
R
P
A
A
I
D
Q
L
V
I
L
G
E
Q
V
G
V
P
V
Y
T
A
G
T
D
V
K
-
P
A
D
I
A
K
Q
G
L
K
E
A
K
K
N
N
V
D
V
V
I
M
D
T
A
G
R
L
Q
I
D
K
G
--
M
M
D
E
L
K
D
V
K
K
F
L
------
N
------
P
T
E
V
L
L
V
V
D
A
M
T
G
Q
E
A
A
A
L
V
T
T
F
N
V
E
I
G
I
T
G
-
A
I
L
T
K
L
D
G
D
S
R
G
G
A
A
L
S
V
K
E
V
S
G
K
P
I
K
L
V
G
R
G
E
R
M
E
D
L
E
P
F
Y
P
D
R
M
A
G
R
I
L
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
104
HHSearch
72.45
35%
-76
* C2 *
-
3DM5
2
SRP54_PYRFU
A:
[2-433]
V
L
D
N
L
G
K
A
L
A
N
T
L
K
K
I
A
R
A
-----------
S
S
V
D
E
A
L
I
K
E
L
V
R
D
I
Q
R
A
L
I
Q
A
D
V
N
V
R
L
V
L
Q
L
T
R
E
I
Q
R
R
A
L
E
E
K
P
P
A
G
I
S
K
K
E
H
I
I
K
I
V
Y
E
E
L
T
K
F
L
G
T
E
---
A
K
P
-----
I
----
E
-------
I
K
E
K
P
T
I
-----
L
L
M
V
G
I
Q
G
S
G
K
T
T
T
V
A
K
L
A
R
Y
F
Q
K
R
-
G
Y
K
V
G
V
V
C
S
D
T
W
R
P
G
A
Y
H
Q
L
R
Q
L
L
D
R
Y
H
I
E
V
F
G
N
P
Q
E
K
D
-
A
I
K
L
A
K
E
G
V
D
Y
F
K
S
K
G
V
D
I
I
I
V
D
T
A
G
R
H
K
E
D
K
A
--
L
I
E
E
M
K
Q
I
S
N
V
I
------
H
------
P
H
E
V
I
L
V
I
D
G
T
I
G
Q
Q
A
Y
N
Q
A
L
A
F
K
E
A
T
P
I
G
S
-
I
I
V
T
K
L
D
G
S
A
K
G
G
G
A
L
S
A
V
A
A
T
G
A
P
I
K
F
I
G
T
G
E
K
I
D
D
I
E
P
F
D
P
P
R
F
V
S
R
L
L
G
L
G
D
I
Q
G
L
L
E
-----
K
F
K
E
L
E
K
E
V
E
I
K
E
E
D
I
E
R
F
-
L
R
-
G
K
F
T
L
K
D
M
Y
A
Q
L
E
A
M
R
K
M
G
P
---------------------
I
S
I
-
G
E
E
R
L
K
K
F
K
V
I
M
D
S
M
T
E
E
E
L
L
N
P
E
I
I
-----
N
Y
S
R
I
K
R
I
A
R
G
S
G
T
---
S
T
K
D
V
K
E
L
L
D
Q
Y
R
Q
M
K
K
L
F
K
S
M
N
K
R
Q
--------------------------------------------------
103
HHSearch
71.85
35%
-82
- C2 -
-
3DM5
2
SRP54_PYRFU
B:
[2-433]
V
L
D
N
L
G
K
A
L
A
N
T
L
K
K
I
A
R
A
-----------
S
S
V
D
E
A
L
I
K
E
L
V
R
D
I
Q
R
A
L
I
Q
A
D
V
N
V
R
L
V
L
Q
L
T
R
E
I
Q
R
R
A
L
E
E
K
P
P
A
G
I
S
K
K
E
H
I
I
K
I
V
Y
E
E
L
T
K
F
L
G
T
E
---
A
K
P
-----
I
----
E
-------
I
K
E
K
P
T
I
-----
L
L
M
V
G
I
Q
G
S
G
K
T
T
T
V
A
K
L
A
R
Y
F
Q
K
R
-
G
Y
K
V
G
V
V
C
S
D
T
W
R
P
G
A
Y
H
Q
L
R
Q
L
L
D
R
Y
H
I
E
V
F
G
N
P
Q
E
K
D
-
A
I
K
L
A
K
E
G
V
D
Y
F
K
S
K
G
V
D
I
I
I
V
D
T
A
G
R
H
K
E
D
K
A
--
L
I
E
-
M
K
Q
I
S
N
V
I
------
H
------
P
H
E
V
I
L
V
I
D
G
T
I
G
Q
Q
A
Y
N
Q
A
L
A
F
K
E
A
T
P
I
G
S
-
I
I
V
T
K
L
D
G
S
A
K
G
G
G
A
L
S
A
V
A
A
T
G
A
P
I
K
F
I
G
T
G
E
K
I
D
D
I
E
P
F
D
P
P
R
F
V
S
R
L
L
G
L
G
D
I
Q
G
L
L
E
-----
K
F
K
E
L
E
K
E
V
E
I
K
E
E
D
I
E
R
F
-
L
R
-
G
K
F
T
L
K
D
M
Y
A
Q
L
E
A
M
R
K
M
G
P
----------------------
S
I
-
G
E
E
R
L
K
K
F
K
V
I
M
D
S
M
T
E
E
E
L
L
N
P
E
I
I
-----
N
Y
S
R
I
K
R
I
A
R
G
S
G
T
---
S
T
K
D
V
K
E
L
L
D
Q
Y
R
Q
M
K
K
L
F
K
S
M
N
K
R
Q
--------------------------------------------------
44
PsiBlast_CBE
70.22
32%
-121
- C5 -
-
5L3Q
5
SRP54_HUMAN
C:
[30-302]
---------------------------------
N
E
E
V
L
N
A
M
L
K
E
V
C
T
A
L
L
E
A
D
V
N
I
K
L
V
K
Q
L
R
E
N
V
K
S
A
I
D
--------
N
K
R
K
M
I
Q
H
A
V
F
K
E
L
V
K
L
V
D
P
G
---
V
K
A
-----
W
----
T
P
------
T
K
G
K
Q
N
V
-----
I
M
F
V
G
L
Q
G
S
G
K
T
T
T
C
S
K
L
A
Y
Y
Y
-
Q
R
K
G
W
K
T
C
L
I
C
A
D
T
F
R
A
G
A
F
D
Q
L
K
Q
N
A
T
K
A
R
I
P
F
Y
G
S
Y
T
E
M
D
-
P
V
I
I
A
S
E
G
V
E
K
F
K
N
E
N
F
E
I
I
I
V
D
T
S
G
R
H
K
Q
E
D
S
--
L
F
E
E
M
L
Q
V
A
N
A
I
------
Q
------
P
D
N
I
V
Y
V
M
D
A
S
I
G
Q
A
C
E
A
Q
A
K
A
F
K
D
K
V
D
V
A
S
-
V
I
V
T
K
L
D
G
H
A
K
G
G
G
A
L
S
A
V
A
A
T
K
S
P
I
I
F
I
G
T
G
E
H
I
D
D
F
E
P
F
K
T
Q
P
F
I
S
K
L
L
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
45
PsiBlast_CBE
70.13
32%
-118
- C5 -
-
5L3Q
5
SRP54_HUMAN
A:
[30-302]
---------------------------------
N
E
E
V
L
N
A
M
L
K
E
V
C
T
A
L
L
E
A
D
V
N
I
K
L
V
K
Q
L
R
E
N
V
K
S
A
I
D
--------
N
K
R
K
M
I
Q
H
A
V
F
K
E
L
V
K
L
V
D
P
G
---
V
K
A
-----
W
----
T
P
------
T
K
G
K
Q
N
V
-----
I
M
F
V
G
L
Q
G
S
G
K
T
T
T
C
S
K
L
A
Y
Y
Y
-
Q
R
K
G
W
K
T
C
L
I
C
A
D
T
F
R
A
G
A
F
D
Q
L
K
Q
N
A
T
K
A
R
I
P
F
Y
G
S
Y
T
E
M
D
-
P
V
I
I
A
S
E
G
V
E
K
F
K
N
E
N
F
E
I
I
I
V
D
T
S
G
R
H
K
Q
E
D
S
--
L
F
E
E
M
L
Q
V
A
N
A
I
------
Q
------
P
D
N
I
V
Y
V
M
D
A
S
I
G
Q
A
C
E
A
Q
A
K
A
F
K
D
K
V
D
V
A
S
-
V
I
V
T
K
L
D
G
H
A
K
G
G
G
A
L
S
A
V
A
A
T
K
S
P
I
I
F
I
G
T
G
E
H
I
D
D
F
E
P
F
K
T
Q
P
F
I
S
K
L
L
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
68.67
40%
-
- C5 -
-
2IY3
-
SRP54_SULSO (first)
A:
[1-429]
M
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
-------------------------
E
A
R
L
P
V
L
KD
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
G
R
R
P
L
L
-
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
E
V
M
D
G
E
S
-
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
--
L
M
G
E
L
A
R
L
K
E
V
L
------
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
-
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
D
I
E
S
I
L
E
-----
K
V
K
G
L
E
E
-
Y
D
K
I
Q
K
K
M
E
D
V
M
E
G
K
G
K
L
T
L
R
D
V
Y
A
Q
I
I
A
L
R
K
M
G
P
L
S
K
V
L
Q
H
I
P
G
L
G
I
M
L
P
T
P
S
E
D
Q
L
K
I
G
E
E
K
I
R
R
W
L
A
A
L
N
S
M
T
Y
K
E
L
E
N
P
N
I
I
-----
D
K
S
R
M
R
R
I
A
E
G
S
G
L
---
E
V
E
E
V
R
E
L
L
E
W
Y
N
N
M
N
R
L
L
K
--------------------------------------------------------
6
PsiBlast_PDB
67.83
36%
-30
- C2 -
-
3DM5
2
SRP54_PYRFU
A:
[2-435]
V
L
D
N
L
G
K
A
L
A
N
T
L
K
K
I
A
R
A
-----------
S
S
V
D
E
A
L
I
K
E
L
V
R
D
I
Q
R
A
L
I
Q
A
D
V
N
V
R
L
V
L
Q
L
T
R
E
I
Q
R
R
A
L
E
E
K
P
P
A
G
I
S
K
K
E
H
I
I
K
I
V
Y
E
E
L
T
K
F
L
G
T
E
---
A
K
P
-----
I
----
E
I
------
K
E
K
P
-
T
I
-----
L
L
M
V
G
I
Q
G
S
G
K
T
T
T
V
A
K
L
A
R
Y
F
Q
K
R
G
Y
K
-
V
G
V
V
C
S
D
T
W
R
P
G
A
Y
H
Q
L
R
Q
L
L
D
R
Y
H
I
E
V
F
-
G
N
P
Q
E
K
D
A
I
K
L
A
K
E
G
V
D
Y
F
K
S
K
G
V
D
I
I
I
V
D
T
A
G
R
H
K
E
D
K
A
--
L
I
E
E
M
K
Q
I
S
N
V
I
------
H
------
P
H
E
V
I
L
V
I
D
G
T
I
G
Q
Q
A
Y
N
Q
A
L
A
F
K
E
A
T
P
I
G
S
-
I
I
V
T
K
L
D
G
S
A
K
G
G
G
A
L
S
A
V
A
A
T
G
A
P
I
K
F
I
G
T
G
E
K
I
D
D
I
E
P
F
D
P
P
R
F
V
S
R
L
L
G
L
G
D
I
Q
G
L
L
E
K
F
K
E
L
E
K
E
V
E
I
K
-
E
E
D
I
E
R
F
L
R
------
G
K
F
T
L
K
D
M
Y
A
Q
L
E
A
M
R
K
M
G
P
-------------------
I
S
I
G
---
E
E
R
L
K
K
F
K
V
I
M
D
S
M
T
E
E
E
L
L
N
P
E
I
I
-----
N
Y
S
R
I
K
R
I
A
R
G
S
G
T
---
S
T
K
D
V
K
E
L
L
D
Q
Y
R
Q
M
K
K
L
F
K
S
M
-
N
K
R
Q
L
S
-----------------------------------------------
26
PsiBlast_CBE
67.29
36%
-32
- C2 -
-
3DM5
2
SRP54_PYRFU
B:
[2-434]
V
L
D
N
L
G
K
A
L
A
N
T
L
K
K
I
A
R
A
-----------
S
S
V
D
E
A
L
I
K
E
L
V
R
D
I
Q
R
A
L
I
Q
A
D
V
N
V
R
L
V
L
Q
L
T
R
E
I
Q
R
R
A
L
E
E
K
P
P
A
G
I
S
K
K
E
H
I
I
K
I
V
Y
E
E
L
T
K
F
L
G
T
E
---
A
K
P
-----
I
----
E
I
------
K
E
K
P
-
T
I
-----
L
L
M
V
G
I
Q
G
S
G
K
T
T
T
V
A
K
L
A
R
Y
F
Q
K
R
G
Y
K
-
V
G
V
V
C
S
D
T
W
R
P
G
A
Y
H
Q
L
R
Q
L
L
D
R
Y
H
I
E
V
F
-
G
N
P
Q
E
K
D
A
I
K
L
A
K
E
G
V
D
Y
F
K
S
K
G
V
D
I
I
I
V
D
T
A
G
R
H
K
E
D
K
A
--
L
I
E
-
M
K
Q
I
S
N
V
I
------
H
------
P
H
E
V
I
L
V
I
D
G
T
I
G
Q
Q
A
Y
N
Q
A
L
A
F
K
E
A
T
P
I
G
S
-
I
I
V
T
K
L
D
G
S
A
K
G
G
G
A
L
S
A
V
A
A
T
G
A
P
I
K
F
I
G
T
G
E
K
I
D
D
I
E
P
F
D
P
P
R
F
V
S
R
L
L
G
L
G
D
I
Q
G
L
L
E
K
F
K
E
L
E
K
E
V
E
I
K
-
E
E
D
I
E
R
F
L
R
------
G
K
F
T
L
K
D
M
Y
A
Q
L
E
A
M
R
K
M
G
P
--------------------
S
I
G
---
E
E
R
L
K
K
F
K
V
I
M
D
S
M
T
E
E
E
L
L
N
P
E
I
I
-----
N
Y
S
R
I
K
R
I
A
R
G
S
G
T
---
S
T
K
D
V
K
E
L
L
D
Q
Y
R
Q
M
K
K
L
F
K
S
M
-
N
K
R
Q
L
------------------------------------------------
89
Fugue
66.04
29%
-42
- C2 -
-
2J37
-
SRP54_CANLF
W:
[8-488]
------
R
K
I
T
S
A
L
R
S
L
S
N
A
-----------
T
I
I
N
E
E
V
L
N
A
M
L
K
E
V
C
T
A
L
L
E
A
D
V
N
I
K
L
V
K
Q
L
R
E
N
V
K
S
A
I
D
L
E
E
M
A
S
G
L
N
K
R
K
M
I
Q
H
A
V
F
K
E
L
V
K
L
V
D
P
G
---
V
K
-----------
A
W
------
T
P
T
K
G
N
V
-----
I
M
F
V
G
L
Q
G
S
G
K
T
T
T
C
S
K
L
A
Y
Y
Y
Q
R
-
K
G
W
K
T
C
L
I
C
A
D
T
F
R
A
G
A
F
D
Q
L
K
Q
N
A
T
K
A
R
I
P
F
Y
G
S
Y
T
E
M
D
-
P
V
I
I
A
S
E
G
V
E
K
F
K
N
E
N
F
E
I
I
I
V
D
T
S
G
R
H
K
Q
E
D
S
--
L
F
E
E
M
L
Q
V
A
N
A
I
------
Q
------
P
D
N
I
V
Y
V
M
D
A
S
I
G
Q
A
C
E
A
Q
A
K
A
F
K
D
K
V
D
V
A
S
-
V
I
V
T
K
L
D
G
H
A
K
G
G
G
A
L
S
A
V
A
A
T
K
S
P
I
I
F
I
G
T
G
E
H
I
D
D
F
E
P
F
K
T
Q
P
F
I
S
K
L
L
G
M
G
D
I
E
G
L
I
D
-----
K
V
N
-
E
L
K
-
L
D
D
N
E
A
L
I
E
K
L
K
H
G
--
Q
F
T
L
R
D
M
Y
E
Q
F
Q
N
I
M
K
M
G
P
F
S
Q
I
L
G
M
I
P
G
F
G
T
D
F
M
S
K
G
-
N
E
Q
E
-
S
M
A
R
L
K
K
L
M
T
I
M
D
S
M
N
D
Q
E
L
D
S
T
D
G
A
KVFSK
Q
P
G
R
I
Q
R
V
A
R
G
S
G
V
---
S
T
R
D
V
Q
E
L
L
T
Q
Y
T
K
F
A
Q
M
V
K
K
M
G
G
I
K
G
L
F
K
G
G
D
M
S
K
N
V
S
Q
S
Q
M
A
K
L
N
Q
Q
M
A
K
M
M
D
P
R
V
L
HHMGGMAGLQSMMRQFQ
9
PsiBlast_PDB
65.57
38%
-14
- C5 -
-
3NDB
-
SRP54_METJA
B:
[1-423]
-
M
D
K
L
G
E
N
L
N
K
A
L
N
K
L
K
A
A
-----------
A
F
V
D
K
K
L
I
K
E
V
I
K
D
I
Q
R
A
L
I
Q
A
D
V
N
V
K
L
V
L
K
M
S
K
E
I
E
R
R
A
L
E
E
K
T
P
K
G
L
S
K
K
E
H
I
I
K
I
V
Y
E
E
L
V
K
L
L
G
E
E
---
A
K
K
-----
L
----
E
L
------
N
P
K
K
Q
N
V
-----
I
L
L
V
G
I
Q
G
S
G
K
T
T
T
A
A
K
L
A
R
Y
I
Q
K
R
G
L
K
P
A
L
-
I
A
A
D
T
Y
R
P
A
A
Y
E
Q
L
K
Q
L
A
E
K
I
H
V
P
I
Y
G
D
E
T
R
T
K
S
P
V
D
I
V
K
E
G
M
E
--
K
F
K
K
A
D
V
L
I
I
D
T
A
G
R
H
K
E
E
K
G
--
L
L
E
E
M
K
Q
I
K
E
I
T
------
N
------
P
D
E
I
I
L
V
I
D
G
T
I
G
Q
Q
A
G
I
Q
A
K
A
F
K
E
A
V
G
E
I
G
S
I
I
V
T
K
L
D
G
S
A
K
G
G
G
A
L
S
A
V
A
E
T
K
A
P
I
K
F
I
G
I
G
E
G
I
D
D
L
E
P
F
D
P
K
K
F
I
S
R
L
L
G
M
G
D
L
E
S
L
L
E
-----
K
A
E
D
M
V
D
--
E
K
T
E
E
S
I
D
A
I
M
R
--
G
K
F
T
L
N
E
L
M
T
Q
L
E
A
I
E
N
M
-----------------------
L
T
---
E
A
K
I
K
K
Y
K
V
I
I
S
S
M
T
K
E
E
R
E
N
P
K
I
I
-----
K
A
S
R
I
R
R
I
A
R
G
S
G
T
T
E
N
D
V
R
E
V
-----------------------------------------------------------------------
50
PsiBlast_CBE
62.48
36%
-68
- C5 -
-
5L3S
1
SRP54_SULSO
C:
[22-298]
------------------------------
S
T
P
Y
E
K
A
V
D
E
F
I
K
D
L
Q
K
S
L
I
S
S
D
V
N
V
K
L
V
F
S
L
T
A
K
I
K
E
R
L
N
K
E
K
-------
K
E
W
F
I
S
I
V
Y
D
E
L
S
K
L
F
G
G
D
---
K
E
P
-----
N
----
V
N
------
P
T
K
L
P
F
I
-----
I
M
L
V
G
V
Q
G
S
G
K
T
T
T
A
G
K
L
A
Y
F
Y
K
K
R
G
Y
K
-
V
G
L
V
A
A
D
V
Y
R
P
A
A
Y
D
Q
L
L
Q
L
G
N
Q
I
G
V
Q
V
Y
G
E
P
N
N
Q
N
-
P
I
E
I
A
K
K
G
V
D
I
F
V
K
N
K
M
D
I
I
I
V
D
T
A
G
R
H
G
Y
G
E
E
T
K
L
L
E
E
M
K
E
M
Y
D
V
L
------
K
------
P
D
D
V
I
L
V
I
D
A
S
I
G
Q
K
A
Y
D
L
A
S
R
F
H
Q
A
S
P
I
G
S
-
V
I
I
T
K
M
D
G
T
A
K
G
G
G
A
L
S
A
V
V
A
T
G
A
T
I
K
F
I
G
T
G
E
K
I
D
E
L
E
T
F
N
A
K
R
F
V
S
R
I
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
46
PsiBlast_CBE
62.29
37%
-59
- C5 -
-
5L3V
1
SRP54_SULSO
B:
[8-299]
-----
L
E
N
I
R
D
A
V
R
K
F
L
T
G
-----------
S
T
P
Y
E
K
A
V
D
E
F
I
K
D
L
Q
K
S
L
I
S
S
D
V
N
V
K
L
V
F
S
L
T
A
K
I
K
E
R
L
N
K
E
K
P
P
S
V
L
E
R
K
E
W
F
I
S
I
V
Y
D
E
L
S
K
L
F
G
G
D
---
K
E
P
-----
N
----
V
N
------
P
T
K
L
P
F
I
-----
I
M
L
V
G
V
Q
G
S
G
K
T
T
T
A
G
K
L
A
Y
F
Y
K
K
R
G
Y
K
-
V
G
L
V
A
A
D
V
Y
R
P
A
A
Y
D
Q
L
L
Q
L
G
N
Q
I
G
V
Q
V
Y
G
E
P
N
N
Q
N
-
P
I
E
I
A
K
K
G
V
D
I
F
V
K
N
K
M
D
I
I
I
V
D
T
A
G
R
H
G
Y
G
E
E
T
K
L
L
E
E
M
K
E
M
Y
D
V
L
------
K
------
P
D
D
V
I
L
V
I
D
A
S
I
G
Q
K
A
Y
D
L
A
S
R
F
H
Q
A
S
P
I
G
S
-
V
I
I
T
K
M
D
G
T
A
K
G
G
G
A
L
S
A
V
V
A
T
G
A
T
I
K
F
I
G
T
G
E
K
I
D
E
L
E
T
F
N
A
K
R
F
V
S
R
I
L
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
47
PsiBlast_CBE
62.23
37%
-51
- C5 -
-
5L3V
1
SRP54_SULSO
A:
[9-299]
------
E
N
I
R
D
A
V
R
K
F
L
T
G
-----------
S
T
P
Y
E
K
A
V
D
E
F
I
K
D
L
Q
K
S
L
I
S
S
D
V
N
V
K
L
V
F
S
L
T
A
K
I
K
E
R
L
N
K
E
K
P
P
S
V
L
E
R
K
E
W
F
I
S
I
V
Y
D
E
L
S
K
L
F
G
G
D
---
K
E
P
-----
N
----
V
N
------
P
T
K
L
P
F
I
-----
I
M
L
V
G
V
Q
G
S
G
K
T
T
T
A
G
K
L
A
Y
F
Y
K
K
R
G
Y
K
-
V
G
L
V
A
A
D
V
Y
R
P
A
A
Y
D
Q
L
L
Q
L
G
N
Q
I
G
V
Q
V
Y
G
E
P
N
N
Q
N
-
P
I
E
I
A
K
K
G
V
D
I
F
V
K
N
K
M
D
I
I
I
V
D
T
A
G
R
H
G
Y
G
E
E
T
K
L
L
E
E
M
K
E
M
Y
D
V
L
------
K
------
P
D
D
V
I
L
V
I
D
A
S
I
G
Q
K
A
Y
D
L
A
S
R
F
H
Q
A
S
P
I
G
S
-
V
I
I
T
K
M
D
G
T
A
K
G
G
G
A
L
S
A
V
V
A
T
G
A
T
I
K
F
I
G
T
G
E
K
I
D
E
L
E
T
F
N
A
K
R
F
V
S
R
I
L
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
59.32
46%
8
- C5 -
-
1JPJ
1
SRP54_THEAQ
A:
[1-294]
M
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
-------------------------
E
A
R
L
P
V
L
KD
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
G
R
R
P
L
L
-
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
E
V
M
D
G
E
S
-
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
--
L
M
G
E
L
A
R
L
K
E
V
L
------
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
-
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
59.16
45%
-1
- C5 -
-
1LS1
3
SRP54_THEAQ
A:
[1-295]
M
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
-------------------------
E
A
R
L
P
V
L
KD
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
G
R
R
P
L
L
-
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
E
V
M
D
G
E
S
-
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
--
L
M
G
E
L
A
R
L
K
E
V
L
------
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
-
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
------
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
PsiBlast_CBE
59.03
46%
18
- C5 -
-
1O87
5
SRP54_THEAQ
B:
[1-295]
M
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
-------------------------
E
A
R
L
P
V
L
KDRNL
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
G
R
R
P
L
L
-
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
E
V
M
D
G
E
S
-
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
--
L
M
G
E
L
A
R
L
K
E
V
L
------
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
-
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
63
PsiBlast_CBE
58.74
37%
-50
- C5 -
-
4C7O
3
FTSY_ECOLI
D:
[19-267]
---------------------------------------------------
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
E
G
A
S
R
K
----
Q
L
R
D
A
E
A
L
Y
G
L
L
K
E
E
M
G
E
I
L
A
K
V
---
D
E
P
-----
L
----
N
V
------
E
G
K
A
P
F
V
-----
I
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
R
Q
F
-
E
Q
Q
G
K
S
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
G
Q
R
N
N
I
P
V
I
A
Q
H
T
G
A
D
-
S
A
S
V
I
F
D
A
I
Q
A
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
--
L
M
E
E
L
K
K
I
V
R
V
M
------
K
K
L
DVEA
P
H
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
G
L
T
G
-
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
57.82
46%
19
- C5 -
-
1JPN
3
SRP54_THEAQ
A:
[1-296]
M
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
-------------------------
E
A
R
L
P
V
L
KD
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
G
R
R
P
L
L
-
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
E
V
M
D
G
E
S
-
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
--
L
M
G
E
L
A
R
L
K
E
V
L
------
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
-
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
PsiBlast_CBE
57.75
45%
19
- C5 -
-
2J7P
4
SRP54_THEAQ
A:
[3-294]
--
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
-------------------------
E
A
R
L
P
V
L
K
D
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
G
R
R
P
L
L
-
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
E
V
M
D
G
E
S
-
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
--
L
M
G
E
L
A
R
L
K
E
V
L
------
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
-
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
PsiBlast_CBE
57.75
46%
15
- C5 -
-
1JPN
3
SRP54_THEAQ
B:
[1-295]
M
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
-------------------------
E
A
R
L
P
V
L
KDRNL
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
G
R
R
P
L
L
-
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
E
V
M
D
G
E
S
-
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
--
L
M
G
E
L
A
R
L
K
E
V
L
------
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
-
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
PsiBlast_CBE
57.49
45%
18
- C5 -
-
1OKK
6
SRP54_THEAQ
A:
[4-293]
---
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
-------------------------
E
A
R
L
P
V
L
KD
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
G
R
R
P
L
L
-
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
E
V
M
D
G
E
S
-
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
--
L
M
G
E
L
A
R
L
K
E
V
L
------
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
-
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
PsiBlast_CBE
57.49
45%
11
- C5 -
-
3NG1
2
SRP54_THEAQ
B:
[1-294]
M
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
-------------------------
E
A
R
L
P
V
L
KDRNL
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
G
R
R
P
L
L
-
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
E
V
M
D
G
E
S
-
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
--
L
M
G
E
L
A
R
L
K
E
V
L
------
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
-
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
PsiBlast_CBE
57.48
45%
11
- C5 -
-
3NG1
2
SRP54_THEAQ
A:
[1-294]
M
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
-------------------------
E
A
R
L
P
V
L
KD
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
G
R
R
P
L
L
-
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
E
V
M
D
G
E
S
-
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
--
L
M
G
E
L
A
R
L
K
E
V
L
------
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
-
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
64
PsiBlast_CBE
57.37
37%
-43
- C5 -
-
4C7O
2
FTSY_ECOLI
B:
[19-267]
---------------------------------------------------
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
E
G
A
S
R
K
----
Q
L
R
D
A
E
A
L
Y
G
L
L
K
E
E
M
G
E
I
L
A
K
V
---
D
E
P
-----
L
----
N
V
------
E
G
K
A
P
F
V
-----
I
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
R
Q
F
-
E
Q
Q
G
K
S
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
G
Q
R
N
N
I
P
V
I
A
Q
H
T
G
A
D
-
S
A
S
V
I
F
D
A
I
Q
A
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
--
L
M
E
E
L
K
K
I
V
R
V
M
------
K
K
L
DVEA
P
H
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
G
L
T
G
-
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
41
PsiBlast_CBE
57.31
45%
11
- C5 -
-
1NG1
8
SRP54_THEAQ
A:
[1-294]
M
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
-------------------------
E
A
R
L
P
V
L
K
D
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
G
R
R
P
L
L
-
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
E
V
M
D
G
E
S
-
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
--
L
M
G
E
L
A
R
L
K
E
V
L
------
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
-
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
57.15
46%
14
- C5 -
-
1O87
4
SRP54_THEAQ
A:
[1-295]
M
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
-------------------------
E
A
R
L
P
V
L
KD
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
G
R
R
P
L
L
-
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
E
V
M
D
G
E
S
-
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
--
L
M
G
E
L
A
R
L
K
E
V
L
------
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
-
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
42
PsiBlast_CBE
56.28
45%
22
- C5 -
-
2NG1
4
SRP54_THEAQ
A:
[1-293]
-
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
T
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
-------------------------
E
A
R
L
P
V
L
KD
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
G
R
R
P
L
L
-
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
E
V
M
D
G
E
S
-
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
--
L
M
G
E
L
A
R
L
K
E
V
L
------
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
-
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
PsiBlast_CBE
56.04
45%
21
- C5 -
-
2J7P
1
SRP54_THEAQ
B:
[4-294]
---
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
-------------------------
E
A
R
L
P
V
L
KD
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
G
R
R
P
L
L
-
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
E
V
M
D
G
E
S
-
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
--
L
M
G
E
L
A
R
L
K
E
V
L
------
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
-
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
66
PsiBlast_CBE
54.18
40%
-58
- C5 -
-
1VMA
1
?
B:
[97-304]
---------------------------------------------------------------------------------------------------------------
L
----
N
V
------
P
P
E
P
P
F
V
-----
I
M
V
V
G
V
N
G
T
G
K
T
T
S
C
G
K
L
A
K
M
F
V
D
-
E
G
K
S
V
V
L
A
A
A
D
T
F
R
A
A
A
I
E
Q
L
K
I
W
G
E
R
V
G
A
T
V
I
S
H
S
E
G
A
D
-
P
A
A
V
A
F
D
A
V
A
H
A
L
A
R
N
K
D
V
V
I
I
D
T
A
G
R
L
H
T
K
K
N
--
L
M
E
E
L
R
K
V
H
R
V
V
------
K
KKIPDA
P
H
E
T
L
L
V
I
D
A
T
T
G
Q
N
G
L
V
Q
A
K
I
F
K
E
A
V
N
V
T
G
-
I
I
L
T
K
L
D
G
T
A
K
G
G
I
T
L
A
I
A
R
E
L
G
I
P
I
K
F
I
G
V
G
E
K
A
E
D
L
R
P
F
D
P
E
A
F
V
E
V
L
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
53.15
46%
29
- C5 -
-
1RJ9
2
SRP54_THEAQ
B:
[14-295]
-------------
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
T
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
-------------------------
E
A
R
L
P
V
L
K
D
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
G
R
R
P
L
L
-
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
E
V
M
D
G
E
S
-
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
--
L
M
G
E
L
A
R
L
K
E
V
L
------
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
-
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
56
PsiBlast_CBE
52.55
33%
21
- C5 -
-
5L3W
1
FTSY_SULAC
A:
[28-306]
--------------------------------
I
K
E
D
D
L
N
D
V
I
E
E
L
R
F
Q
L
L
D
S
D
V
S
Y
E
V
T
E
K
I
L
E
D
L
K
N
N
L
I
G
K
K
V
----
S
R
R
E
E
V
E
E
I
V
I
N
T
L
K
K
S
I
T
E
I
L
TK
N
Q
K
-----
T
----
D
L
I
E
K
I
R
S
S
G
K
K
P
F
V
-----
I
I
F
F
G
V
N
G
V
G
K
T
T
T
I
A
K
V
V
N
M
L
K
K
N
N
L
S
T
I
I
A
A
S
-
D
T
F
R
A
A
A
Q
E
Q
L
A
Y
H
A
S
K
L
E
V
Q
L
I
R
G
K
Y
G
A
D
-
P
A
S
V
A
F
D
A
I
S
F
A
K
S
R
N
I
D
V
V
L
I
D
T
A
G
R
M
H
I
D
S
D
--
L
V
E
E
L
K
R
V
L
R
I
A
------
K
------
P
D
F
R
I
L
I
L
D
S
L
A
G
S
D
A
L
E
Q
A
R
H
F
E
N
N
V
G
Y
D
A
-
V
I
L
T
K
V
D
A
D
A
K
G
G
I
A
L
S
L
A
Y
E
L
K
K
P
V
V
Y
M
G
V
G
Q
N
Y
D
D
L
I
P
F
S
P
D
W
F
V
E
R
I
F
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
109
HHSearch
52.13
35%
30
- C5 -
-
3E70
2
?
C:
[7-324]
M
F
G
K
L
R
E
K
L
K
S
F
V
K
R
V
E
E
E
VEKEEEEVILT
V
E
I
K
E
K
D
V
D
K
A
L
D
E
L
E
I
D
L
L
E
A
D
V
A
L
E
V
V
D
A
L
R
E
K
I
K
Q
K
L
V
G
K
K
V
R
I
G
---
G
K
I
I
E
E
A
V
K
E
A
V
S
E
I
L
E
T
S
---
R
R
I
-----
D
LIEE
I
R
------
K
A
E
K
P
Y
V
-----
I
M
F
V
G
F
N
G
S
G
K
T
T
T
I
A
K
L
A
N
W
L
K
N
H
-
G
F
S
V
V
I
A
A
S
D
T
F
R
A
G
A
I
E
Q
L
E
E
H
A
K
R
I
G
V
K
V
I
K
H
S
Y
G
A
D
-
P
A
A
V
A
Y
D
A
I
Q
H
A
K
A
R
G
I
D
V
V
L
I
D
T
A
G
R
S
E
T
N
R
N
--
L
M
D
E
M
K
K
I
A
R
V
T
------
K
------
P
N
L
V
I
F
V
G
D
A
L
A
G
N
A
I
V
E
Q
A
R
Q
F
N
E
A
V
K
I
D
G
-
I
I
L
T
K
L
D
A
D
A
R
G
G
A
A
L
S
I
S
Y
V
I
D
A
P
I
L
F
V
G
V
G
Q
G
Y
D
D
L
R
P
F
E
K
E
W
F
L
E
R
I
F
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
120
HHSearch
51.08
31%
18
- C5 -
-
5L3W
1
FTSY_SULAC
A:
[15-305]
--------
N
K
R
S
F
F
D
F
L
K
Y
-----------
K
T
I
K
E
D
D
L
N
D
V
I
E
E
L
R
F
Q
L
L
D
S
D
V
S
Y
E
V
T
E
K
I
L
E
D
L
K
N
N
L
I
G
K
K
V
S
R
R
E
E
V
E
E
I
V
I
N
T
L
K
K
S
I
T
E
I
L
T
K
N
---
Q
K
T
D
L
I
E
K
I
----
R
S
------
S
G
K
K
P
F
V
-----
I
I
F
F
G
V
N
G
V
G
K
T
T
T
I
A
K
V
V
N
M
L
K
K
N
-
N
L
S
T
I
I
A
A
S
D
T
F
R
A
A
A
Q
E
Q
L
A
Y
H
A
S
K
L
E
V
Q
L
I
R
G
K
Y
G
A
D
-
P
A
S
V
A
F
D
A
I
S
F
A
K
S
R
N
I
D
V
V
L
I
D
T
A
G
R
M
H
I
D
S
D
--
L
V
E
E
L
K
R
V
L
R
I
A
------
K
------
P
D
F
R
I
L
I
L
D
S
L
A
G
S
D
A
L
E
Q
A
R
H
F
E
N
N
V
G
Y
D
A
-
V
I
L
T
K
V
D
A
D
A
K
G
G
I
A
L
S
L
A
Y
E
L
K
K
P
V
V
Y
M
G
V
G
Q
N
Y
D
D
L
I
P
F
S
P
D
W
F
V
E
R
I
F
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
85
PsiBlast_CBE
47.86
37%
-32
- C5 -
-
1RJ9
2
FTSY_THEAQ
A:
[115-302]
--------------------------------------------------------------------------------------------------------------------------------------------------
K
T
T
T
I
A
K
L
G
R
Y
Y
-
Q
N
L
G
K
K
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
R
L
S
I
P
V
I
Q
G
P
E
G
T
D
-
S
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
--
L
M
E
E
L
K
K
V
K
R
A
I
A
K
A
DPE
E
------
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
-
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
80
PsiBlast_CBE
47.61
38%
-28
- C5 -
-
2J7P
4
FTSY_THEAQ
D:
[94-281]
--------------------------------------------------------------------------------------------------------------------------------------------------
K
T
T
T
I
A
K
L
G
R
Y
Y
-
Q
N
L
G
K
K
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
R
L
S
I
P
V
I
Q
G
P
E
G
T
D
-
P
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
--
L
M
E
E
L
K
K
V
K
R
A
I
A
K
A
DPE
E
------
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
-
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
79
PsiBlast_CBE
47.50
38%
-28
- C5 -
-
2J7P
1
FTSY_THEAQ
E:
[94-281]
--------------------------------------------------------------------------------------------------------------------------------------------------
K
T
T
T
I
A
K
L
G
R
Y
Y
-
Q
N
L
G
K
K
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
R
L
S
I
P
V
I
Q
G
P
E
G
T
D
-
P
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
--
L
M
E
E
L
K
K
V
K
R
A
I
AKADPE
E
------
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
-
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
72
PsiBlast_CBE
47.46
38%
-29
- C5 -
-
1OKK
6
FTSY_THEAQ
D:
[114-301]
--------------------------------------------------------------------------------------------------------------------------------------------------
K
T
T
T
I
A
K
L
G
R
Y
Y
-
Q
N
L
G
K
K
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
R
L
S
I
P
V
I
Q
G
P
E
G
T
D
-
P
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
--
L
M
E
E
L
K
K
V
K
R
A
I
AKADPE
E
------
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
-
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
81
PsiBlast_CBE
46.01
38%
-37
- C5 -
-
2IYL
1
FTSY_THEAQ
D:
[95-282]
--------------------------------------------------------------------------------------------------------------------------------------------------
K
T
T
T
I
A
K
L
G
R
Y
Y
-
Q
N
L
G
K
K
V
M
F
C
A
G
D
T
------
T
Q
L
S
E
W
G
K
R
L
S
I
P
V
I
Q
G
P
E
G
T
D
-
P
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
--
L
M
E
E
L
K
K
V
K
R
A
I
AKADPE
E
------
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
--
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
-
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
52
PsiBlast_CBE
46.00
35%
21
- C5 -
-
3E70
2
?
C:
[46-324]
-------------------------------
E
I
K
E
K
D
V
D
K
A
L
D
E
L
E
I
D
L
L
E
A
D
V
A
L
E
V
V
D
A
L
R
E
K
I
K
Q
K
L
V
G
K
K
V
R
I
G
---
G
K
I
I
E
E
A
V
K
E
A
V
S
E
I
L
-
E
T
---
S
R
R
-----
I
----
D
L
IEEIR-
K
A
E
K
P
Y
V
-----
I
M
F
V
G
F
N
G
S
G
K
T
T
T
I
A
K
L
A
N
W
L
K
-
N
H
G
F
S
V
V
I
A
A
S
D
T
F
R
A
G
A
I
E
Q
L
E
E
H
A
K
R
I
G
V
K
V
I
K
H
S
Y
G
A
D
-
P
A
A
V
A
Y
D
A
I
Q
H
A
K
A
R
G
I
D
V
V
L
I
D
T
A
G
R
S
E
T
N
R
N
--
L
M
D
E
M
K
K
I
A
R
V
T
------
K
------
P
N
L
V
I
F
V
G
D
A
L
A
G
N
A
I
V
E
Q
A
R
Q
F
N
E
A
V
K
I
D
G
-
I
I
L
T
K
L
D
A
D
A
R
G
G
A
A
L
S
I
S
Y
V
I
D
A
P
I
L
F
V
G
V
G
Q
G
Y
D
D
L
R
P
F
E
K
E
W
F
L
E
R
I
F
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
74
PsiBlast_CBE
45.50
38%
-31
- C5 -
-
2Q9C
1
FTSY_THEAQ
A:
[115-302]
--------------------------------------------------------------------------------------------------------------------------------------------------
K
T
T
T
I
A
K
L
G
R
Y
Y
-
Q
N
L
G
K
K
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
R
L
S
I
P
V
I
Q
G
P
E
G
T
D
-
P
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
--
L
M
E
E
L
K
K
V
K
R
A
I
A
K
A
DPE
E
------
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
-
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
76
PsiBlast_CBE
44.41
38%
-25
- C5 -
-
2Q9B
5
FTSY_THEAQ
A:
[115-302]
--------------------------------------------------------------------------------------------------------------------------------------------------
K
T
T
T
I
A
K
L
G
R
Y
Y
-
Q
N
L
G
K
K
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
R
L
S
I
P
V
I
Q
G
P
E
G
T
D
-
P
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
--
L
M
E
E
L
K
K
V
K
R
A
I
A
K
A
DPE
E
------
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
-
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------