@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VU31: (2017-12-16 )
MFESLIPLFSIAMALMLGAISPGPSFIYVAQNSISKSRKHGLFTALGTGTGAALFGFLAVMGLQAVLLAVPSAYLILKIGGGLYLLWLAFKIIKHAKEPIAMENDAKSKMTYKQAYRYGLITQLSNPKIAVVLASVFTALLPKEIPNYYYVALPLICFMIDAGWYSCIAMLLSSEKPRKMYLKAKTGVDRVAGSIVSVLGLKLIFFK
Atome Classification :
(20 SA)
------------------------.........10.------........20..---------..-.--...30..-....---------------------..40-------....-....50-------......---..60-..-.....-------.70-.---------.......80.......-.90........----100--...-......110....-----.-...-120..-....-.130...-----....140.---....-----------..150.......160-........-.170-.-.....--------...180.......190.......200-----.....--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
------------------------M
F
E
S
L
I
P
L
F
S
-
I
------
A
M
A
L
M
L
GAISPG---------P
S
-
F
--
I
Y
V
AQNS-ISKS---------------------RKH
G
-------
L
F
T
A-LGTG
T
G
-------
A
A
L
F
G
F
---
L
A
V
M
-
G
L
-
Q
A
V
L
L
-------AVP-
S
---------
A
Y
L
I
L
K
IGG
G
L
Y
L
L
W
L
-
A
F
K
I
I
K
HAKEP----I----AME-NDAKS
K
M
T
-
Y
K
Q
A
-----
Y
-RYG-
L
I
TQL-SNP
K
-
I
A
V
V
L
A
S
-----
V
F
T
A
L
L
P
K
---EIP
N
-----------
Y
Y
Y
V
A
L
P
L
I
C
F
M
I---D
A
G
W
Y
S
C
I
-
A
M
---
L
-LSSEK--------P
R
K
M
Y
L
K
AKT
G
V
D
R
V
A
G
S
I
V
S
V
LG
L
K
-----
L
I
F
FK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
Fugue
61.82
20%
-7
- C5 -
-
3GN6
4
?
A:
[22-321]
FNPWT
D
A
A
L
D
T
IVNQALTL
Y
A
E
M
R
V
V
P
A
H
H
D
A
F
L
-
A
------
A
I
D
T
V
S
A
K
L
R
V
L
---------
P
G
-
F
--
L
S
L
A
L
K
Q
M
S
G
D
S
TMVKNYPETYKGVLAT
A
Y
L
D
G
V
A
A
G
TQ
P
Y
F
Y
N
L
F
V
R
-
F
A
D
G
R
A
-------
A
R
A
A
G
F
---
E
A
L
F
-
E
T
-
H
I
H
P
L
-------
L
H
A
M
A
DGPEL
L
A
Y
R
A
V
L
Q
S
V
V
A
G
D
R
H
A
I
Y
R
G
A
E
E
I
R
S
F
L
R
R
P
----
V
------
E
-
L
P
E
R
E
T
V
T
-
V
E
N
H
-----
V
M
V
P
E
-
D
K
H
A
A
-
W
E
P
Q
-
V
A
I
L
L
Q
V
-----
A
Q
D
T
F
E
P
Q
---
D
E
P
S
GVG
L
P
G
A
RDNR
Y
Y
R
K
A
L
S
T
E
I
L
R
N
AHA
D
G
G
L
R
A
Y
I
M
H
G
---
V
-
W
E
S
V
W
D
H
E
N
S
H
L
D
P
R
F
L
A
A
A
G
P
V
G
A
A
A
V
V
G
P
V
E
P
F
Y
L
T
R
-----
R
L
V
V
A
D-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
Fugue
60.62
23%
-35
- C7 -
-
4XGC
-
ORC5_DROME
E:
[1-458]
---------------------M
E
A
I
C
S
S
L
E
P
L
F
P
-
C
R
E
A
A
I
E
T
L
G
E
L
I
G
D
S
S
E
T
Y--------
P
S
-
A
--
I
Y
L
F
G
H
S
-------------------------------------------
G
T
G
K
T
-------
A
L
T
R
A
F
---
L
K
E
C
-
G
K
R
Q
N
V
R
T
-------
A
H
L
-
N
---------
A
I
E
C
Y
T
--
T
K
I
M
L
E
I
L
-
L
D
S
L
A
P
D
Q
G
D
A
----
L
----
K
V
D
-
N
----
M
L
D
-
F
V
E
Q
-----
L
-
R
R
Q
-
A
A
T
R
V
-
E
D
Q
G
-
F
L
I
A
V
D
N
-----------
A
E
---
R
L
R
D
-----------
M
D
A
N
V
L
P
V
L
L
R
L
Q
---
E
L
T
N
L
N
L
C
-
V
I
---
L
-
L
S
Q
L
P
--------
F
E
K
F
Y
--
N
K
T
G
L
S
E
I
-------
V
C
L
H
-----
L
A
Q
Y
N
K
A
E
T
Q
R
I
L
G
SD
F
Q
Q
V
R
N
Q
L
L
E
QK
K
R
L
E
I
C
Q
E
A
VT
E
D
F
Y
N
N
Y
L
N
L
F
L
S
V
F
YKACRD
V
P
E
L
Q
L
T
A
R
K
C
L
S
T
Y
L
EPVLDGTSRLWR
H
I
A
G
P
L
R
S
A
L
T
Q
IYMRIES
L
E
L
P
Y
Y
A
K
F
L
L
I
A
A
F
L
A
S
H
N
AAKQDKRLFSTTL
G
P
K
S
F
S
I
D
R
L
L
A
I
F
Y
A
I
LEEKVGLT
C
N
L
L
S
Q
I
S
T
L
V
H
L
NL
L
S
F
V
S
GEQNIME
G
S
A
R
L
Q
C
T
I
G
L
E
F
V
L
Q
I
G
K
V
V
GFNVRQYLCD
21
Fugue
55.81
19%
-82
- C7 -
-
5M1P
-
?
A:
[3-189]
---------------------------
A
M
N
S
V
F
S
G
L
------
D
M
L
I
L
L
P
Y
E
R
R
G
TRLVVEDYR
P
D
-
H
--
I
Y
C
I
G
A
D
-
F
G
K
N
---------------------
Q
D
Y
S
-------
V
F
S
V
-
L
D
L
D
T
G
---------
A
I
A
C
---
L
E
R
M
-
N
G
-
A
T
W
S
D
-------
Q
V
A
-
R
---------
L
K
A
L
S
E
D
Y
G
H
A
Y
V
V
A
D
-
T
W
G
V
G
D
A
I
A
E
E
----
L
----
D
A
Q
-
G
-----
I
N
-
Y
T
P
--------------
L
P
V
-
K
S
S
S
-
V
K
E
Q
L
I
S
-----
N
L
A
L
L
M
E
K
GQV
A
V
P
N
-----------
D
K
T
I
L
D
E
L
R
N
F
R
Y
---
Y
R
---------------
T
A
S
G
--------
N
Q
V
M
R
A
Y
-----
G
R
G
H
D
D
I
V
M
S
L
A
L
A
-----
Y
S
Q
Y
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
52.42
23%
-99
- C6 -
-
3FUX
1
RSMA_THET8
A:
[50-157]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
F
E
V
G
P
G
L
G
A
L
T
R
-
A
--
L
L
E
A
G
A
E
V
----
T
----
A
I
E
-
K
D
L
R
L
R
P
V
-
L
E
E
T
L
SG
L
P
V
-
R
L
V
-
F
Q
D
A
L
-
L
Y
P
W
-
E
E
V
P
Q
G
S
-----
L
L
V
A
N
L
P
--------------------
Y
H
I
A
T
P
L
V
T
R
L
L
---
K
T
G
R
F
A
R
L
-
V
F
---
L
-
V
Q
K
E
V
--------
A
E
R
M
T
A
R
P
K
T
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
52.14
23%
-95
- C6 -
-
3FUU
1
RSMA_THET8
A:
[50-157]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
F
E
V
G
P
G
L
G
A
L
T
R
-
A
--
L
L
E
A
G
A
E
V
----
T
----
A
I
E
-
K
D
L
R
L
R
P
V
-
L
E
E
T
L
SGLP
V
-
R
L
V
-
F
Q
D
A
L
-
L
Y
P
W
-
E
E
V
P
Q
G
S
-----
L
L
V
A
N
L
P
--------------------
Y
H
I
A
T
P
L
V
T
R
L
L
---
K
T
G
R
F
A
R
L
-
V
F
---
L
-
V
Q
K
E
V
--------
A
E
R
M
T
A
R
P
K
T
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
51.71
23%
-93
* C6 *
-
3FUW
1
RSMA_THET8
A:
[50-157]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
F
E
V
G
P
G
L
G
A
L
T
R
-
A
--
L
L
E
A
G
A
E
V
----
T
----
A
I
E
-
K
D
L
R
L
R
P
V
-
L
E
E
T
L
SGLP
V
-
R
L
V
-
F
Q
D
A
L
-
L
Y
P
W
-
E
E
V
P
Q
G
S
-----
L
L
V
A
N
L
P
--------------------
Y
H
I
A
T
P
L
V
T
R
L
L
---
K
T
G
R
F
A
R
L
-
V
F
---
L
-
V
Q
K
E
V
--------
A
E
R
M
T
A
R
P
K
T
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
48.79
23%
-94
- C- -
-
3FUV
-
RSMA_THET8
A:
[50-157]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
F
E
V
G
P
G
L
G
A
L
T
R
-
A
--
L
L
E
A
G
A
E
V
----
T
----
A
I
E
-
K
D
L
R
L
R
P
V
-
L
E
E
T
L
SG
L
P
V
-
R
L
V
-
F
Q
D
A
L
-
L
Y
P
W
-
E
E
V
P
Q
G
S
-----
L
L
V
A
N
L
P
--------------------
Y
H
I
A
T
P
L
V
T
R
L
L
---
K
T
G
R
F
A
R
L
-
V
F
---
L
-
V
Q
K
E
V
--------
A
E
R
M
T
A
R
P
K
T
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
Fugue
47.57
14%
-93
- C3 -
-
4XLG
-
SLX1_CANGA
A:
[3-300]
------------------------
E
F
Q
Q
I
P
D
F
Y
---------
G
C
Y
L
L
Q
S
I
S
K
R
Q
---------
S
F
-
Y
--
I
G
S
T
P
N
P
-
V
R
R
L
---------------------
R
Q
H
N
-------
G
S
L
S
-
R
T
K
R
D
G
TRPWEMV
A
I
V
Y
G
F
PS
R
I
A
A
L
-
Q
F
-
Q
H
A
W
Q
H
GTRYIS
I
H
H
-
K
---------
L
A
M
I
T
S
L
L
K
N
E
Y
F
R
Y
M
-
D
L
T
L
H
F
F
N
Q
K
V
----
E
----
E
I
W
-
K
N
D
K
F
N
V
S
N
Y
T
V
S
-----
L
-
S
Q
D
-
A
L
T
E
I
-
N
N
D
T
-
I
D
D
I
M
D
V
N
E
K
N
M
E
L
V
Q
N
L
Y
S
---
T
T
L
A
-----------
E
K
T
K
T
L
L
L
Y
K
E
K
I
---
D
T
G
I
N
T
C
Q
-
F
C
NKI
I
-
K
H
N
N
I
--------
S
E
N
L
F
A
F
C
R
D
----
T
S
C
T
F
V
S
H
L
A
C
A
-----
Y
R
Y
F
M
SEDTIIPQSPKCPKCYTLLK
W
C
D
V
I
Y
Y
S
I
K
L
N
K-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
Fugue
46.44
15%
-25
- C4 -
-
4FLE
-
?
A:
[3-197]
----------------S
T
L
L
Y
I
H
G
F
N
S
S
P
S
S
A
K
A
-
T
------
T
F
K
S
W
L
Q
Q
H
H
P
H
---------
I
E
M
Q
--
I
P
Q
L
P
P
Y
-
P
A
E
A
A
E
M
L
E
S
I
V
M
D
-----------
K
A
G
Q
-------
S
I
G
I
-
V
G
S
S
L
G
-------
G
Y
F
A
T
W
---
L
S
Q
R
F
S
I
-
P
A
V
V
V
NP-----
A
V
R
-
P
---------
F
E
L
L
S
D
Y
L
G
---------
E
N
Q
N
P
Y
T
G
Q
K
----
Y
----
V
L
E
-
S
R
H
I
Y
D
L
K
--------------
A
M
Q
I
E
K
L
-
E
S
P
D
L
L
W
L
L
Q
Q
T
-----
G
D
E
V
L
D
Y
R
---
Q
A
V
A
-----------
Y
Y
T
P
C
R
Q
T
V
E
S
G
G
---
N
H
A
F
----------------------------------
V
G
F
D
H
Y
F
S
P
I
V
T
F
L
G
L
A
-----
T
A
L
E
H
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
Fugue
42.27
17%
-101
- C2 -
-
5LNK
-
NU6M_SHEEP
J:
[1-175]
------------------------
M
M
T
Y
I
V
F
I
L
S
-
I
------
I
F
V
M
G
F
V
G
F
S
S
K
---------
P
S
-------------
P
I
Y
---------------------
G
G
L
G
-------
L
I
V
S
-
G
G
V
G
C
G
-------
I
V
L
N
F
G
---
G
S
F
L
-
G
L
-
M
V
F
L
I
-------
Y
L
G
-
G
---------
M
M
V
V
F
G
Y
T
T
A
M
A
T
E
---
Q
Y
P
E
V
W
V
S
N
K
V
----
V
----
L
G
T
-
F
I
T
G
L
L
M
E
-
F
L
M
V
-----
Y
-
Y
V
------
L
-
K
D
K
E
-
V
E
I
V
F
K
-------
F
N
G
M
G
D
W
---
V
I
Y
D
-----------
T
G
--------------
D
S
G
F
F
S
E
E
-
A
M
---
G
-
I
A
A
L
Y
--------
S
Y
G
T
W
L
V
I
V
T
G
W
S
L
L
I
G
V
V
V
I
M
E
I
T
R
-----
G
N
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
Fugue
39.74
12%
-130
- C- -
-
2PN7
-
GGCT_HUMAN
A:
[14-182]
--------------------------
E
E
S
F
L
Y
F
A
-
Y
------
G
S
N
L
L
T
E
R
I
H
L
R
---------
N
P
-
S
--
A
A
F
F
C
V
A
-
R
L
Q
D
---------------------
F
K
L
D
-------
F
G
N
S
-
Q
G
K
T
S
Q
-------
T
W
-----------------------------
H
-
G
---------
G
I
A
T
I
F
Q
S
P
G
D
E
V
W
G
V
-
V
W
K
M
N
K
S
N
L
N
S
----
L
----
D
E
Q
-
E
G
V
K
S
G
M
Y
-
V
V
I
E
-----
V
-
K
V
A
-
T
Q
E
G
--------------------------
K
---
E
I
T
C
-----------
R
S
Y
L
M
T
N
Y
E
S
A
P
P
---
S
P
Q
Y
K
K
I
I
-
C
M
---
G
-
A
K
E
N
G
--------
L
P
L
E
Y
Q
E
K
L
K
A
I
E
P
N
D
Y
T
G
K
V
S
E
E
I
E
-----
D
I
I
K
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
37.69
50%
-317
- C- -
-
2B0A
-
Y783_METJA
A:
[162-185]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
Y
F
L
G
L
P
L
K
I
F
D
I
---
D
A
S
P
I
R
C
I
-
A
I
---
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
33.65
17%
-190
- C1 -
-
3S8F
3
COXA_THET8
C:
[22-27]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
W
L
G
V
Y
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
Fugue
32.38
12%
-
- C- -
-
4PON
-
?
A:
[1-191]
--------------------------
M
I
L
K
K
I
L
P
-
Y
------
S
K
E
L
L
K
M
A
A
G
E
G
---------
D
I
-
V
--
I
D
A
-----------------------------------------------
T
M
G
N
G
-------
H
D
T
Q
F
L
---
A
E
L
V
-
G
E
-
N
---------------------------------
G
H
V
Y
A
F
D
I
-
Q
E
S
A
V
A
N
T
K
E
R
----
L
------
G
-
E
A
Y
Q
A
R
T
T
-
L
F
H
K
-----
S
-
H
D
K
-
I
A
K
S
L
-
P
P
E
T
-
H
G
K
V
A
A
A
-----
V
F
N
L
----------
G
-----------
N
G
S
S
T
I
K
A
I
E
Q
L
L
---
S
I
M
K
D
E
G
L
-
I
V
---
L
-
V
V
Y
H
G
--------
N
D
V
L
D
F
C
R
N
L
D
Q
Q
A
A
R
V
L
T
Y
G
F
I
N
Q
Q
ND
P
P
F
I
V
A
I
E
K
K
AQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
32.16
15%
-107
- C6 -
-
2N4X
-
?
A:
[11-196]
-------------------------------
Q
L
M
-
A
------
F
A
L
G
I
L
S
V
F
S
P
A
---------
V
L
-
P
VV
P
L
I
F
A
G
S
-
R
-
G
R
---------------------
A
L
D
A
-------
F
L
I
V
-
A
G
L
T
I
S
-------
M
L
I
L
G
Y
---
T
A
S
L
-
F
--
F
---------------------------
G
F
F
R
V
V
A
M
L
F
L
L
I
F
-
A
L
I
L
L
S
D
E
L
D
E
K
---
V
S
I
F
A
S
R
M
T
S
G
L
S
W
K
I
Q
-
T
L
P
S
-----
F
-
F
F
G
-
M
L
L
A
F
L
W
L
P
A
-
I
L
P
F
A
G
I
-----
A
I
S
Q
T
L
L
S
---
E
--
N
--------------
P
L
V
M
L
S
Y
G
L
G
---
M
A
V
T
I
A
A
V
-
F
K
---
M
---
G
E
-----------
K
F
V
K
A
N
F
Q
L
I
R
K
V
T
G
A
I
V
L
L
Y
L
A
Y
-----
F
A
L
T
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
24.34
13%
-402
- C6 -
-
5B66
-
PSBX_THEVL
X:
[3-25]
------------------------
I
T
P
S
L
K
G
F
F
I
-
G
------
L
L
S
G
A
V
V
L
G
L
T
F
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
24.24
13%
-369
- C6 -
-
4RVY
-
PSBX_THEEB
X:
[3-25]
------------------------
I
T
P
S
L
K
G
F
F
I
-
G
------
L
L
S
G
A
V
V
L
G
L
T
F
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
Fugue
24.23
13%
-39
* C7 *
-
4V2B
-
UNC5D_RAT
A:
[47-152]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
-
P
G
T
L
P
H
F
I
E
E
P
E
D
A
Y
I
----
I
K
S
-
N
P
I
A
L
R
C
K
-
A
R
P
A
-----
M
-
Q
I
F
-
F
K
C
N
G
-
E
W
V
H
-
Q
N
E
H
V
S
E
-----
E
S
L
D
L
K
V
R
---
E
V
F
I
-----------
N
V
T
R
Q
Q
V
E
D
F
H
G
P
---
E
D
Y
W
C
Q
C
V
-
A
W
---
S
H
L
G
T
S
K
--------
S
R
K
A
S
V
R
I
A
Y
L
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
23.06
39%
-7
- C6 -
-
4HVL
-
?
A:
[82-122]
---------------------------------------------------
E
P
G
---------
G
D
-
F
--
V
D
A
A
G
N
G
-
M
S
D
C
---------------------
D
A
H
G
-------
T
L
T
A
S
V
I
A
G
R
G
-------
A
P
T
D
G
F
---
I
G
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
Fugue
21.08
23%
115
- C6 -
-
2M5E
-
B:
[1-26]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
R
K
-
Q
E
E
V
S
A
I
V
-
I
Q
R
A
-----
Y
-
R
R
Y
-
L
L
K
Q
K
-
V
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------