@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VV54: (2017-12-22 )
MIATSIEQIPNIPCFDDSPRGRLLHGAAYLFHKQGYDKTTVRELAQFIGIQSGSLFHHFKSKDDILAHVMEQTIIYNLARLNDAVTQSTDPEQQLRALIKAELISITGDTGAAMAVLVYEWFALSKEKQDYLLKMRNEYEQIWLDVIEKLRTQGKVKHDAFIWRRLIGGAISLTVTWYKSEGKVKIDELTEMVWEMALK
Atome Classification :
(20 SA)
.........10........20.-.......30........40........50........60........70........80........90........100.......110.......120--------.---......130.......140....-...150......------.-160.......170...-.-..-.180.......190.......
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MIA
T
S
I
E
QIPNIPCFDDSPRG
R
-
L
L
H
G
A
A
Y
L
F
HKQGY
D
K
T
T
V
R
E
L
A
Q
F
IGIQSG
S
L
F
H
HFKSK
D
D
I
L
A
H
V
M
E
Q
T
I
I
Y
N
L
A
R
LNDAVTQST
D
P
E
Q
Q
L
R
A
L
I
K
A
E
L
I
S
ITGDT
G
A
A
M
A
V
L
V
Y
E
W
F
--------A---LS
K
E
K
Q
D
Y
L
L
K
M
R
N
E
Y
E
Q
I
W
L
D
V
-
I
E
K
L
R
TQGKV
K
H
------
D
-
A
F
I
W
R
R
L
IG
G
A
I
S
L
T
V
-
T
-
W
Y-KSEG
K
V
K
I
D
E
L
T
E
M
V
W
E
M
ALK
1
PsiBlast_PDB
89.71
49%
-151
- C1 -
-
4MO7
1
?
A:
[28-210]
----------------
E
S
A
R
G
K
-
L
L
Q
T
A
A
H
L
F
R
N
K
G
F
E
R
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R
D
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H
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E
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I
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Y
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A
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R
V
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A
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I
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C
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G
E
A
M
A
V
L
V
Y
E
W
R
--------
S
---
L
S
A
E
G
Q
A
H
V
L
A
L
R
D
V
Y
E
Q
I
W
L
Q
V
-
L
G
E
A
K
A
A
G
Y
I
R
G
------
D
-
V
F
I
T
R
R
F
L
T
G
A
L
S
W
T
T
-
T
-
W
F
-
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A
Q
G
S
L
T
L
E
E
L
A
E
E
A
L
L
M
V
L
K
168
HHSearch
89.39
48%
-156
- C1 -
-
4MO7
1
?
A:
[25-209]
-------------
T
D
P
E
S
A
R
G
K
-
L
L
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A
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E
A
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R
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A
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A
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E
W
R
--------
S
---
L
S
A
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A
H
V
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A
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E
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I
W
L
Q
V
-
L
G
E
A
K
A
A
G
Y
I
R
G
------
D
-
V
F
I
T
R
R
F
L
T
G
A
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T
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-
T
-
W
F
-
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Q
G
S
L
T
L
E
E
L
A
E
E
A
L
L
M
V
L
-
159
HHSearch
87.66
47%
-155
- C1 -
-
4MXM
-
?
A:
[7-195]
---------
S
G
Q
L
T
D
P
E
S
A
R
G
K
-
L
L
Q
T
A
A
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K
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F
E
R
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A
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F
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K
D
E
I
L
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A
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N
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A
M
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A
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E
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E
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V
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A
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C
E
L
Q
S
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S
G
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A
M
A
V
---
E
W
R
--------
S
---
L
S
A
E
G
Q
A
H
V
L
A
L
R
D
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E
Q
I
W
L
Q
V
-
L
G
E
A
K
A
A
G
Y
I
R
G
------
D
-
V
F
I
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R
R
F
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G
A
L
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T
T
-
T
-
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A
Q
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S
L
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E
E
L
A
E
E
A
L
L
M
V
L
-
2
PsiBlast_PDB
80.68
48%
-143
- C1 -
-
4MXM
-
?
A:
[14-181]
----------------
E
S
A
R
G
K
-
L
L
Q
T
A
A
H
L
F
R
N
K
G
F
E
R
T
T
V
R
D
L
A
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A
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G
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Q
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G
S
I
F
H
H
F
K
S
K
D
E
I
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A
V
M
E
E
T
I
H
Y
N
T
A
M
M
R
A
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E
E
A
S
T
V
R
E
R
V
L
A
L
I
R
C
E
L
Q
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I
M
G
G
S
G
E
A
M
A
V
---
E
W
R
--------
S
---
L
S
A
E
G
Q
A
H
V
L
A
L
R
D
V
Y
E
Q
I
W
L
Q
V
-
L
G
E
A
K
A
A
G
Y
I
R
G
------
D
-
V
F
I
T
R
R
F
L
T
G
A
L
S
W
T
T
-
T
-
W
F
-
R
A
Q
G
S
L
---------------
3
PsiBlast_PDB
64.25
27%
-68
- C1 -
-
4W97
1
KSTR2_MYCTU
A:
[9-185]
----------------
N
S
R
R
G
E
-
L
L
E
L
A
A
A
M
F
A
E
R
G
L
R
A
T
T
V
R
D
I
A
D
G
A
G
I
L
S
G
S
L
Y
H
H
F
A
S
K
E
E
M
V
D
E
L
L
R
G
F
L
D
W
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F
A
R
Y
R
D
I
V
D
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A
N
P
L
E
R
L
Q
G
L
F
M
A
S
F
E
A
I
E
H
H
H
A
---
Q
V
V
I
Y
Q
D
E
--------
A
QRL
A
S
Q
P
R
F
S
Y
I
E
D
R
N
K
Q
Q
R
K
M
W
V
D
V
-
L
N
Q
G
I
E
E
G
Y
F
R
P
DL----
D
-
V
D
L
V
Y
R
F
I
R
D
T
T
W
V
S
V
-
R
-
W
Y
-
R
P
G
G
P
L
T
A
Q
Q
V
G
Q
--------
161
HHSearch
64.24
23%
-109
- C1 -
-
3DCF
-
?
A:
[29-209]
----------------
N
D
R
R
T
Q
-
I
I
K
V
A
T
E
L
F
R
E
K
G
Y
Y
A
T
S
L
D
D
I
A
D
R
I
G
F
T
K
P
A
I
Y
Y
Y
F
K
S
K
E
D
V
L
F
A
I
V
N
S
I
V
D
E
A
L
E
R
F
H
A
I
A
A
G
P
G
S
P
G
E
R
I
H
A
L
L
V
E
H
T
R
T
I
L
R
N
L
-
D
A
N
T
L
F
Y
N
---------------
L
S
P
E
R
E
R
E
M
R
K
R
E
R
E
Y
T
E
I
M
Q
R
L
-
Y
A
E
G
V
A
T
G
E
L
L
D
V-----
D
-
P
T
V
A
T
A
T
L
L
G
A
A
I
W
T
Y
-
R
-
W
Y
-
D
P
E
G
R
L
S
A
D
E
V
V
E
Q
I
T
R
L
L
--
6
PsiBlast_PDB
64.17
24%
-127
- C- -
-
3CCY
-
?
A:
[13-191]
-------------------
R
D
T
-
I
I
E
R
A
A
A
M
F
A
R
Q
G
Y
S
E
T
S
I
G
D
I
A
R
A
C
E
C
S
K
S
R
L
Y
H
Y
F
D
S
K
E
A
V
L
R
D
M
L
T
T
H
V
D
S
L
L
E
R
C
R
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V
L
Y
G
S
N
E
P
K
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R
F
L
Q
I
V
K
L
-
F
L
E
I
Y
A
T
S
R
D
R
H
V
V
M
L
T
C
L
D
--------
A
---
L
P
E
D
Q
R
K
A
L
I
A
K
Q
R
E
L
I
A
Y
V
R
D
A
-
L
L
Q
L
R
P
D
M
A
A
N
R
------
T
L
A
H
V
D
T
M
L
F
F
G
M
I
N
W
T
Y
-
T
-
W
Y
-
K
A
D
G
S
V
S
P
D
A
L
A
E
R
T
V
Q
L
F
L
-
157
HHSearch
63.58
20%
-108
- C- -
-
3HIM
-
?
B:
[12-195]
-------------
L
G
T
S
K
A
A
A
R
-
I
R
A
A
A
I
E
V
F
A
A
K
G
Y
G
A
T
T
T
R
E
I
A
A
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G
A
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P
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A
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A
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A
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A
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V
T
W
H
A
D
N
R
-
A
S
A
R
V
G
Q
Y
E
L
R
--------
S
---
L
S
P
E
H
F
A
I
I
A
D
I
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T
K
V
F
T
R
I
-
I
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A
G
A
T
A
G
D
F
H
P
F-----
D
-
I
E
A
A
A
L
A
I
T
S
L
G
I
D
V
S
-
R
-
W
F
-
P
S
H
T
Y
S
D
P
R
I
I
A
A
R
Y
V
E
L
A
--
12
PsiBlast_PDB
62.65
21%
-126
* C1 *
-
5GPA
-
?
A:
[7-189]
------------
P
K
Y
D
-----
Q
-
I
I
D
A
A
V
Q
V
I
A
E
H
G
Y
H
Q
A
Q
V
S
K
I
A
K
A
A
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Y
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L
A
A
D
H
K
L
A
I
V
T
----
Q
L
--------
E
---
L
----
T
E
L
A
L
K
I
-
N
E
V
L
K
G
Y
L
N
L
-
L
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E
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L
M
E
G
K
E
K
G
YFFQEL
D
-
T
R
L
A
R
Q
M
I
F
G
T
L
D
E
V
V
-
T
N
W
V
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M
K
D
C
K
Y
D
L
T
A
L
V
K
P
V
H
Q
L
L
L
-
18
PsiBlast_PDB
62.09
24%
-112
- C1 -
-
3DCF
-
?
A:
[32-211]
-------------------
R
T
Q
-
I
I
K
V
A
T
E
L
F
R
E
K
G
Y
Y
A
T
S
L
D
D
I
A
D
R
I
G
F
T
K
P
A
I
Y
Y
Y
F
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K
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F
A
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A
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A
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A
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G
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A
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E
H
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R
T
I
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N
L
D
-
A
N
T
L
F
Y
N
---------------
L
S
P
E
R
E
R
E
M
R
K
R
E
R
E
Y
T
E
I
M
Q
R
L
Y
A
E
G
V
A
T
G
E
L
L
D
V
------
D
-
P
T
V
A
T
A
T
L
L
G
A
A
I
W
T
Y
-
R
-
W
Y
-
D
P
E
G
R
L
S
A
D
E
V
V
E
Q
I
T
R
L
L
L
N
14
PsiBlast_PDB
61.16
21%
-118
- C1 -
-
5GPC
2
?
A:
[6-188]
------------
P
K
Y
D
-----
Q
-
I
I
D
A
A
V
Q
V
I
A
E
H
G
Y
H
Q
A
Q
V
S
K
I
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A
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A
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F
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M
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Q
L
A
A
D
H
K
L
A
I
V
T
----
Q
L
--------
E
---
L
R
Q
S
N
T
E
L
R
L
K
I
-
N
E
V
L
K
G
Y
L
N
L
-
L
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E
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L
M
E
G
K
E
K
G
YFFQEL
D
-
T
R
L
A
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Q
M
I
F
G
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E
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V
-
T
N
W
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M
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D
C
K
Y
D
L
T
A
L
V
K
P
V
H
Q
L
L
L
-
162
HHSearch
60.48
21%
-126
- C1 -
-
3WHC
2
FADR_BACSU
E:
[4-187]
---------------
K
R
P
K
Y
M
Q
-
I
I
D
A
A
V
E
V
I
A
E
N
G
Y
H
Q
S
Q
V
S
K
I
A
K
Q
A
G
V
A
D
G
T
I
Y
L
Y
F
K
N
K
E
D
I
L
I
S
L
F
K
E
K
M
G
Q
F
I
E
R
M
E
E
D
I
K
E
K
A
T
A
K
E
K
L
A
L
V
I
S
K
H
F
S
L
L
A
G
D
H
-
N
L
A
I
V
T
Q
L
E
L
R
--------
Q
---
S
N
L
E
L
R
Q
K
I
N
E
I
L
K
G
Y
L
N
I
L
D
G
I
-
L
T
E
G
I
Q
S
G
E
I
K
E
GL----
D
-
V
R
L
A
R
Q
M
I
F
G
T
I
D
E
T
V
T
T
-
W
V
-
M
N
D
Q
K
Y
D
L
V
A
L
S
N
S
V
L
E
L
L
--
158
HHSearch
60.41
20%
-101
- C- -
-
3HIM
-
?
A:
[14-195]
---------------
T
S
K
A
A
A
R
-
I
R
A
A
A
I
E
V
F
A
A
K
G
Y
G
A
T
T
T
R
E
I
A
A
S
L
D
M
S
P
G
A
V
Y
P
H
Y
K
T
K
E
S
L
L
Y
A
I
S
L
E
G
H
H
S
V
L
A
A
I
T
A
A
D
F
P
D
I
A
A
P
D
R
L
M
S
T
V
T
A
Y
V
T
W
H
A
D
N
R
-
A
S
A
R
V
G
Q
Y
E
L
R
--------
S
---
L
S
P
E
H
F
A
I
I
A
D
I
R
R
S
T
T
K
V
F
T
R
I
-
I
E
A
G
A
T
A
G
D
F
H
P
F-----
D
-
I
E
A
A
A
L
A
I
T
S
L
G
I
D
V
S
-
R
-
W
F
-
P
S
H
T
Y
S
D
P
R
I
I
A
A
R
Y
V
E
L
A
--
167
HHSearch
60.14
14%
-144
- C1 -
-
2PBX
-
?
B:
[7-198]
-------
K
R
P
R
T
R
L
S
P
Q
K
R
K
L
Q
-
L
M
E
I
A
L
E
V
F
A
K
R
G
I
G
R
G
G
H
A
D
I
A
E
I
A
Q
V
S
V
A
T
V
F
N
Y
F
P
T
R
E
D
L
V
D
D
V
L
N
F
V
V
R
Q
Y
S
N
F
L
T
D
H
I
D
L
D
L
D
V
K
T
N
L
Q
T
L
C
K
E
M
V
K
L
A
M
T
D
C
-
H
W
L
K
V
W
F
E
W
S
A
--------
S
---
T
R
D
E
V
W
P
L
F
V
S
T
N
R
T
N
Q
L
L
I
R
N
M
-
F
M
K
A
M
E
R
G
E
L
C
E
KH----
D
-
V
D
N
M
A
S
L
F
H
G
I
F
Y
S
I
F
-
L
-
Q
V
N
R
L
G
E
Q
E
A
V
Y
K
L
A
D
S
Y
L
N
M
L
--
13
PsiBlast_PDB
59.98
21%
-118
- C1 -
-
5GP9
2
?
A:
[6-188]
------------
P
K
Y
D
-----
Q
-
I
I
D
A
A
V
Q
V
I
A
E
H
G
Y
H
Q
A
Q
V
S
K
I
A
K
A
A
G
V
A
D
G
T
I
Y
L
Y
F
N
N
K
E
D
V
L
I
S
L
F
Q
E
K
M
G
R
F
V
D
K
I
R
S
Q
M
N
E
A
T
D
V
E
E
K
L
K
I
L
V
N
M
H
F
K
Q
L
A
A
D
H
K
L
A
I
V
T
----
Q
L
--------
E
---
L
R
Q
S
N
T
E
L
R
L
K
I
-
N
E
V
L
K
G
Y
L
N
L
-
L
D
E
L
L
M
E
G
K
E
K
G
YFFQEL
D
-
T
R
L
A
R
Q
M
I
F
G
T
L
D
E
V
V
-
T
N
W
V
-
M
K
D
C
K
Y
D
L
T
A
L
V
K
P
V
H
Q
L
L
L
-
163
HHSearch
58.31
23%
-69
- C1 -
-
3VPR
-
?
A:
[2-181]
----------------
T
T
T
R
D
R
-
I
L
E
E
A
A
K
L
F
T
E
K
G
Y
E
A
T
S
V
Q
D
L
A
Q
A
L
G
L
S
K
A
A
L
Y
H
H
F
G
S
K
E
E
I
L
Y
E
I
S
L
L
A
L
K
G
L
V
A
A
G
E
K
A
L
E
V
-
A
D
P
K
E
A
L
R
R
F
M
E
A
H
A
R
Y
F
E
E
N
Y
-
P
F
F
V
T
M
L
Q
G
I
K
--------
S
---
L
S
P
E
N
R
L
K
T
I
A
L
R
D
R
H
E
E
N
L
R
A
I
-
L
R
R
G
V
E
Q
G
V
F
R
E
V-----
D
-
V
A
L
A
G
R
A
V
L
S
M
L
N
W
M
I
-
R
-
W
F
-
R
P
D
G
P
M
R
A
E
E
V
A
R
A
Y
H
D
L
I
--
164
HHSearch
57.52
23%
-81
- C1 -
-
3VPR
-
?
B:
[3-181]
-----------------
T
T
R
D
R
-
I
L
E
E
A
A
K
L
F
T
E
K
G
Y
E
A
T
S
V
Q
D
L
A
Q
A
L
G
L
S
K
A
A
L
Y
H
H
F
G
S
K
E
E
I
L
Y
E
I
S
L
L
A
L
K
G
L
V
A
A
G
E
K
A
L
E
V
-
A
D
P
K
E
A
L
R
R
F
M
E
A
H
A
R
Y
F
E
E
N
Y
-
P
F
F
V
T
M
L
Q
G
I
K
--------
S
---
L
S
P
E
N
R
L
K
T
I
A
L
R
D
R
H
E
E
N
L
R
A
I
-
L
R
R
G
V
E
Q
G
V
F
R
E
V-----
D
-
V
A
L
A
G
R
A
V
L
S
M
L
N
W
M
I
-
R
-
W
F
-
R
P
D
G
P
M
R
A
E
E
V
A
R
A
Y
H
D
L
I
--
17
PsiBlast_PDB
56.63
19%
-41
- C1 -
-
5K7Z
2
?
A:
[16-190]
------------------
E
R
Y
R
A
I
L
E
T
A
A
R
L
I
C
D
R
G
Y
E
G
T
S
M
Q
E
I
A
A
A
C
R
M
T
K
A
G
L
Y
H
H
I
Q
N
K
E
Q
L
L
F
A
I
M
N
Y
G
M
D
L
F
E
E
Q
V
L
S
R
V
Q
D
I
A
N
P
V
E
R
L
R
A
C
M
R
H
N
I
L
L
V
T
R
G
W
S
K
E
V
I
I
I
L
H
E
H
A
--------
T
---
L
T
G
E
T
R
A
F
I
D
A
R
K
K
K
Y
V
D
F
L
E
E
A
-
F
S
Q
A
S
Q
Q
G
L
I
R
P
V-----
D
-
P
T
V
G
A
F
S
F
L
G
M
V
L
W
I
Y
-
K
-
W
F
-
K
P
D
G
R
L
T
D
E
Q
I
A
D
--------
5
PsiBlast_PDB
56.63
23%
-48
- C1 -
-
3VPR
-
?
A:
[3-183]
-----------------
T
T
R
D
R
-
I
L
E
E
A
A
K
L
F
T
E
K
G
Y
E
A
T
S
V
Q
D
L
A
Q
A
L
G
L
S
K
A
A
L
Y
H
H
F
G
S
K
E
E
I
L
-
Y
E
I
S
L
L
A
L
K
G
L
V
A
A
G
E
K
A
L
E
V
A
D
P
K
E
A
L
R
R
F
M
E
A
H
A
R
Y
F
E
E
N
---------
Y
P
F
F
V
T
M
L
Q
G
I
K
S
---
L
S
P
E
N
R
L
K
T
I
A
L
R
D
R
H
E
E
N
L
R
A
I
-
L
R
R
G
V
E
Q
G
V
F
R
E
V-----
D
-
V
A
L
A
G
R
A
V
L
S
M
L
N
W
M
I
-
R
-
W
F
-
R
P
D
G
P
M
R
A
E
E
V
A
R
A
Y
H
D
L
I
L
R
173
HHSearch
56.56
17%
-128
- C1 -
-
5GP9
3
?
B:
[7-188]
------------------
K
Y
D
Q
-
I
I
D
A
A
V
Q
V
I
A
E
H
G
Y
H
Q
A
Q
V
S
K
I
A
K
A
A
G
V
A
D
G
T
I
Y
L
Y
F
N
N
K
E
D
V
L
I
S
L
F
Q
E
K
M
G
R
F
V
D
K
I
R
S
Q
M
N
E
A
T
D
V
E
E
K
L
K
I
L
V
N
M
H
F
K
Q
L
A
A
D
H
-
K
L
A
I
V
T
Q
L
E
L
R
--------
Q
---
S
N
T
E
L
R
L
K
I
N
E
V
L
K
G
Y
L
N
L
L
D
E
L
-
L
M
E
G
K
E
K
G
Y
F
F
Q
EL----
D
-
T
R
L
A
R
Q
M
I
F
G
T
L
D
E
V
V
T
N
-
W
V
-
M
K
D
C
K
Y
D
L
T
A
L
V
K
P
V
H
Q
L
L
L
-