@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : I3TZU2: (2017-12-17 )
MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSAYQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQQIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKKNQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIGDAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARFREIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELPLINQIKAGMNYQFIRKEGR
Atome Classification :
(20 SA)
---.........10........20........30..---.....---------------.40--------------.---------------.-.-------------------......50........60..-......70----..--------------......80........90.....-..---.100......---.110-.........--120.......130........140.........150...--------....160.......170.......180-..--.--....190.......200.......210.-.......220.......230...---....240.--....---..250....-.-..260.......270.....-.-.--280.......290.......300........310-------...-....320.......330.......340.......350.---------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
---MF
G
F
S
I
F
MNDSL
S
E
E
K
K
Q
Y
I
R
Q
M
A
SNG
F
V
G
I
F
T
---SMHIP---------------
E
D
---------------
D
---------------
V
-
S
-------------------
A
Y
Q
K
R
L
I
E
LGSEAKKN
K
L
E
L
-
M
V
DIS
G
E
A
----
L
E
--------------RAGFSLEDLTP
L
K
A
IGVT
G
L
R
M
D
-
Y
H---ISN
Q
Q
I
ADW
S
---
H
Q
---
L
K
I
S
LNAST--IT
P
K
D
I
D
E
L
K
E
-AEA
D
F
S
Q
I
E
A
--
W
HNYYPRPETGL
D
K
E
--------
W
Y
Q
KKN
Q
W
L
K
I
Q
G
L
L
V
Q
G
FVPGDTELR-G
P
--
L
--YQGLP
T
L
E
E
HRGIH
P
L
A
G
A
L
D
L
LASN-T-
D
I
V
Y
IGDAGLS
E
N
V
Q
E
Q
F
A
S
F
QK---E
Q
T
V
L
L
HT--EPV
D
---
E
E
F
Y
E
Y
I
L
G-K-HTNR
Q
D
D
A
R
D
V
I
R
S
V
D
A
R
F
R-E-I--PPIPARNTATRMK
G
S
I
T
LD
N
E
-
K
Y
L
R
Y
MG
E
I
Q
L
T
-------KYD-LPA
D
E
K
V
N
V
V
A
K
V
I
K
E
EL
P
L
I
N
Q
I
K
AGM
N
Y
Q
F
I
RKEGR---------
21
HHSearch
81.96
50%
-47
- C4 -
-
2P0O
-
?
A:
[4-361]
---
M
Y
G
I
S
V
F
L
G
E
E
I
T
N
D
T
I
I
Y
I
K
K
M
K
A
L
G
F
D
G
I
F
T
---
S
L
H
I
P
----------------------------------------------------------------------
L
Y
R
Q
R
L
T
D
L
G
A
I
A
K
A
E
K
M
K
I
-
M
V
D
I
S
G
E
A
----
L
K
--------------
R
A
G
F
S
F
D
E
L
E
P
L
I
E
L
G
V
T
G
L
R
M
D
-
Y
G
---
I
T
I
E
Q
M
A
H
A
S
---
H
K
---
I
D
I
G
L
N
A
S
T
--
I
T
L
E
E
V
A
E
L
K
A
-
H
Q
A
D
F
S
R
L
E
A
--
W
H
N
Y
Y
P
R
P
E
T
G
I
G
T
T
--------
F
F
N
E
K
N
R
W
L
K
E
L
G
L
Q
V
F
T
F
V
P
G
D
G
Q
T
R
-
G
P
--
I
--
F
A
G
L
P
T
L
E
K
H
R
G
Q
N
P
F
A
A
A
V
G
L
M
A
D
P
Y
V
-
D
A
V
Y
I
G
D
P
T
I
S
E
R
T
M
A
Q
F
G
Y
Y
H
Q
---
T
N
Q
F
L
L
E
V
--
A
P
S
E
S--
R
Y
L
K
R
I
L
-
G
-
T
-
H
T
N
R
L
D
A
A
R
D
V
L
R
S
E
L
----------
A
T
I
E
S
E
Q
T
E
A
R
P
V
G
T
V
T
I
D
N
E
-
K
Y
G
R
Y
M
G
E
I
Q
V
T
-------
L
V
D
-
L
P
K
D
E
K
V
N
T
I
T
R
I
I
D
K
D
Q
T
I
L
P
L
I
K
A
G
N
Q
F
T
L
V
T
E
G
-----------
1
PsiBlast_PDB
81.92
49%
-61
- C4 -
-
2P0O
-
?
A:
[5-358]
----
Y
G
I
S
V
F
L
G
E
E
I
T
N
D
T
I
I
Y
I
K
K
M
K
A
L
G
F
D
G
I
F
T
---
S
L
H
I
P
----------------------------------------------------------------------
L
Y
R
Q
R
L
T
D
L
G
A
I
A
K
A
E
K
M
K
I
-
M
V
D
I
S
G
E
A
----
L
K
--------------
R
A
G
F
S
F
D
E
L
E
P
L
I
E
L
G
V
T
G
L
R
M
D
-
Y
G
---
I
T
I
E
Q
M
A
H
A
S
---
H
K
---
I
D
I
G
L
N
A
S
T
--
I
T
L
E
E
V
A
E
L
K
A
-
H
Q
A
D
F
S
R
L
E
A
--
W
H
N
Y
Y
P
R
P
E
T
G
I
G
T
T
--------
F
F
N
E
K
N
R
W
L
K
E
L
G
L
Q
V
F
T
F
V
P
G
D
G
Q
T
R
-
G
P
--
I
--
F
A
G
L
P
T
L
E
K
H
R
G
Q
N
P
F
A
A
A
V
G
L
M
A
D
P
Y
V
-
D
A
V
Y
I
G
D
P
T
I
S
E
R
T
M
A
Q
F
G
Y
Y
H
Q
---
T
N
Q
F
L
L
E
V
--
A
P
S
E
---
S
R
Y
L
K
R
I
L
G
-
T
-
H
T
N
R
L
D
A
A
R
D
V
L
R
S
E
L
----------
A
T
I
E
S
E
Q
T
E
A
R
P
V
G
T
V
T
I
D
N
E
-
K
Y
G
R
Y
M
G
E
I
Q
V
T
-------
L
V
D
-
L
P
K
D
E
K
V
N
T
I
T
R
I
I
D
K
D
Q
T
I
L
P
L
I
K
A
G
N
Q
F
T
L
V
--------------
41
Fugue
63.93
27%
20
- C- -
-
1X7F
-
?
A:
[1-361]
M
E
R
K
L
G
I
S
L
Y
P
E
H
S
T
K
E
K
D
M
A
Y
I
S
A
A
A
R
H
G
F
S
R
I
F
T
---
C
L
L
-------------------------------------------------------------------------
S
V
A
E
F
K
E
I
I
N
H
A
K
D
N
N
M
E
V
-
I
L
D
V
A
P
A
V
----
F
Y
--------------------
S
D
L
S
F
F
A
E
L
G
A
D
G
I
R
L
D
-
V
G
---
F
D
G
L
T
E
A
K
M
T
N
NP
Y
G
---
L
K
I
E
L
N
V
S
N
--
D
I
A
-
Y
L
E
N
I
L
S
-
H
Q
A
N
K
S
A
L
I
G
--
C
H
N
F
Y
P
Q
K
F
T
G
L
P
Y
D
--------
Y
F
I
R
C
S
E
R
F
K
K
H
G
I
R
S
A
A
F
I
T
S
H
V
A
N
I
-
G
P
WD
I
--
N
D
G
L
C
T
L
E
E
H
R
N
L
P
I
E
V
Q
A
K
H
L
W
A
T
G
-
L
I
D
D
V
I
I
G
N
A
Y
A
S
E
E
E
L
E
K
L
G
N
L
N
R
---
Y
M
L
Q
L
K
V
H
F
V
D
E
A
T
---
E
V
E
K
R
A
T
L
Q
-
E
L
H
V
R
R
G
D
I
T
E
Y
M
V
R
S
T
E
V
R
K
K
Y
K
-
D
--
Y
D
F
P
V
R
E
S
V
L
Q
E
R
G
Q
V
V
I
G
N
N
-
S
F
G
K
Y
K
G
E
L
Q
I
I
-------
L
K
E
-
M
P
I
D
E
R
K
N
I
V
G
T
I
A
E
E
E
L
F
L
L
D
Y
V
G
A
W
T
Q
F
T
C
V
E
-------------
22
HHSearch
62.09
27%
22
- C- -
-
1X7F
-
?
A:
[4-361]
---
K
L
G
I
S
L
Y
P
E
H
S
T
K
E
K
D
M
A
Y
I
S
A
A
A
R
H
G
F
S
R
I
F
T
---
C
L
L
S
V
-------------------------------------------------------------------------
A
E
F
K
E
I
I
N
H
A
K
D
N
N
M
E
V
-
I
L
D
V
A
P
A
V
----
F
--------------------
Y
S
D
L
S
F
F
A
E
L
G
A
D
G
I
R
L
D
-
V
G
---
F
D
G
L
T
E
A
K
M
T
---
N
N
PYG
L
K
I
E
L
N
V
S
N
---
D
I
A
Y
L
E
N
I
L
S
-
H
Q
A
N
K
S
A
L
I
G
--
C
H
N
F
Y
P
Q
K
F
T
G
L
P
Y
D
--------
Y
F
I
R
C
S
E
R
F
K
K
H
G
I
R
S
A
A
F
I
T
S
H
V
A
N
I
-
G
P
--
W
DI
N
D
G
L
C
T
L
E
E
H
R
N
L
P
I
E
V
Q
A
K
H
L
W
A
T
G
L
I
-
D
D
V
I
I
G
N
A
Y
A
S
E
E
E
L
E
K
L
G
N
L
N
R
---
Y
-
M
L
Q
L
K
V
--
H
F
V
D
EAT
E
V
E
K
R
A
T
L
Q
E
L
-
H
V
R
R
G
D
I
T
E
Y
M
V
R
S
T
E
V
R
K
K
-
Y
K
D
--
Y
D
F
P
V
R
E
S
V
L
Q
E
R
G
Q
V
V
I
G
N
N
-
S
F
G
K
Y
K
G
E
L
Q
I
I
-------
L
K
E
-
M
P
I
D
E
R
K
N
I
V
G
T
I
A
E
E
E
L
F
L
L
D
Y
V
G
A
W
T
Q
F
T
C
V
E
-------------
2
PsiBlast_PDB
59.55
26%
19
- C- -
-
1X7F
-
?
A:
[5-360]
----
L
G
I
S
L
Y
P
E
H
S
T
K
E
K
D
M
A
Y
I
S
A
A
A
R
H
G
F
S
R
I
F
T
C
L
L
S
V
-------------------------------------------------------------------------
A
E
F
K
E
I
I
---
N
H
A
K
D
N
N
M
E
V
-
I
L
D
V
A
P
A
V
----
F
--------------------
Y
S
D
L
S
F
F
A
E
L
G
A
D
G
I
R
L
D
-
V
G
FDG
L
T
E
A
K
M
T
N
N
P
---
Y
G
---
L
K
I
E
L
N
V
S
N
--
D
I
A
Y
-
L
E
N
I
L
S
-
H
Q
A
N
K
S
A
L
I
G
--
C
H
N
F
Y
P
Q
K
F
T
G
L
P
Y
D
--------
Y
F
I
R
C
S
E
R
F
K
K
H
G
I
R
S
A
A
F
I
T
S
H
V
A
N
I
-
G
P
WD
I
--
N
D
G
L
C
T
L
E
E
H
R
N
L
P
I
E
V
Q
A
K
H
L
W
A
T
G
L
I
-
D
D
V
I
I
G
N
A
Y
A
S
E
E
E
L
E
K
L
G
N
L
N
R
Y
M
L
Q
L
K
V
H
F
V
D
--
E
A
T
E
---
V
E
K
R
A
T
L
Q
E
-
L
-
H
V
R
R
G
D
I
T
E
Y
M
V
R
S
T
E
V
R
K
K
Y
K
-
D
--
Y
D
F
P
V
R
E
S
V
L
Q
E
R
G
Q
V
V
I
G
N
N
-
S
F
G
K
Y
K
G
E
L
Q
I
I
-------
L
K
E
-
M
P
I
D
E
R
K
N
I
V
G
T
I
A
E
E
E
L
F
L
L
D
Y
V
G
A
W
T
Q
F
T
C
V
--------------
36
HHSearch
38.54
15%
-5
- C4 -
-
3VGF
4
TREZ_SULSF
A:
[121-191]
------------------
V
I
R
K
L
D
Y
L
K
D
L
G
I
T
A
I
E
I
---
M
P
I
A
Q
---------------
F
P
---------------
G
KRDWGYDGVYLYAVQ
N
S
Y
-------------------
G
G
P
E
G
F
R
K
L
V
D
E
A
H
K
K
G
L
G
V
-
I
L
D
V
V
Y
N
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
HHSearch
38.47
18%
-31
- C4 -
-
2D73
-
SUSB_BACTN
B:
[370-470]
---------------
T
A
N
V
K
R
Y
I
D
F
A
A
A
H
G
F
D
A
V
L
-------
V
----------------
E
G
---------------
W
---------------
N
-
E
GWEDWFGNSKDYVFDFVTP
Y
P
D
F
D
V
K
E
I
H
R
Y
A
A
R
K
G
I
K
M
-
M
M
H
H
E
T
S
A
SVRN
Y
E
R-------------
H
M
D
-
K
A
--
Y
Q
F
M
A
D
N
G
Y
N
S
V
K
S
G
-
Y
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
HHSearch
37.83
19%
-60
- C4 -
-
5E1Q
2
AGAL_BACTN
B:
[322-413]
---------------
N
P
T
Y
K
A
Y
I
D
F
A
S
A
N
G
I
E
Y
V
I
-------
L
D
---------------
E
G
---------------
W
---------------
A
-
V
NLQADLMQV----------
V
K
E
I
D
L
K
E
L
V
D
Y
A
A
S
K
N
V
G
I
-
I
L
W
A
G
Y
H
A
----
F
E
--------------
R
D
--
M
E
N
V
C
R
H
Y
A
E
M
G
V
K
G
F
K
V
G
-
F
M
---
D
R
D
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
37.58
15%
40
- C4 -
-
2DH2
-
A:
[37-147]
-----------------
G
L
K
G
R
L
D
Y
L
S
S
L
K
V
K
G
L
V
L
---
G
P
I
H
K
---------------
N
Q
KDDVAQTDLLQI---
D
---------------
P
N
F
-------------------
G
S
K
E
D
F
D
S
L
L
Q
S
A
K
K
K
S
I
R
V
-
I
L
D
L
T
P
N
Y
----
R
G
ENSWFSTQV
D
T
V
A
T
K
V
K
-
D
A
--
L
E
F
W
L
Q
A
G
V
D
G
F
Q
V
R
-
D
I
---
E
N
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
37.10
15%
36
- C4 -
-
2DH3
-
B:
[37-147]
-----------------
G
L
K
G
R
L
D
Y
L
S
S
L
K
V
K
G
L
V
L
---
G
P
I
H
K
---------------
N
Q
KDDVAQTDLLQI---
D
---------------
P
N
F
-------------------
G
S
K
E
D
F
D
S
L
L
Q
S
A
K
K
K
S
I
R
V
-
I
L
D
L
T
P
N
Y
----
R
G
ENSWFSTQ
V
D
T
V
A
T
K
V
K
-
D
A
--
L
E
F
W
L
Q
A
G
V
D
G
F
Q
V
R
-
D
I
---
E
N
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
HHSearch
34.49
13%
10
- C4 -
-
5BRQ
-
?
D:
[41-111]
-----------------
G
I
I
E
K
L
D
Y
I
K
E
L
A
C
D
V
I
W
L
---
T
P
I
Y
Q
---------------
S
P
---------------
Q
NDNGYDISDYYSIHE
E
-
Y
-------------------
G
T
M
A
D
F
E
E
L
L
E
E
A
H
K
R
G
I
K
V
-
I
M
D
L
V
V
N
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
HHSearch
34.01
15%
21
- C4 -
-
1EH9
-
TREZ_SULSF
A:
[122-191]
-------------------
I
R
K
L
D
Y
L
K
D
L
G
I
T
A
I
E
I
---
M
P
I
A
Q
---------------
F
P
GKRDWGYDGVYLYAV
Q
N--------------
S
-
Y
-------------------
G
G
P
E
G
F
R
K
L
V
D
E
A
H
K
K
G
L
G
V
-
I
L
D
V
V
Y
N
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
49
Fugue
33.47
10%
23
- C3 -
-
1USH
-
?
?:
[26-362]
--------------
Y
E
Q
D
K
T
Y
K
I
T
V
L
H
T
N
D
H
H
G
H
F
W
---
R
N
E
Y
G
---------------
E
Y
---------------
G
---------------
L
-
A
-------------------
A
Q
K
T
L
V
D
G
I
R
K
E
V
A
A
E
G
G
S
V
-
L
L
L
S
G
G
D
I
----
N
T
--------------
G
V
P
E
S
D
L
Q
D
A
E
P
D
F
R
G
M
N
L
V
G
Y
D
-
A
M
A
--
I
G
N
H
E
F
D
N
P
L
---
T
V
---
L
R
Q
Q
E
K
W
A
K
FP
L
L
S
A
N
I
Y
Q
K
S
T
-
G
E
R
L
F
K
P
------------------
W
A
--------
L
F
K
R
Q
D
L
K
I
A
V
I
G
L
T
T
D
D
T
A
K
I
G
N
P
----
E
--
Y
--
F
T
D
I
E
F
R
K
P
A
D
E
A
K
L
V
I
Q
E
L
Q
Q
T
E
K
P
-
D
-
I
I
I
A
A
T
H
M
G
H
Y
D
N
G
E
H
G
----
S
N
---
A
P
G
D
V
E
M
A
--
R
A
L
P
---
A
G
S
L
A
M
I
V
G
-
G
-
H
S
Q
D
P
-----
V
C
M
A
A
E
N
K
K
Q
-
V
-
D
--
Y
V
P
G
T
P
C
K
P
D
Q
Q
N
G
I
W
I
V
Q
A
H
-
E
W
G
K
Y
V
G
R
A
D
F
E
-------
F
R
N
G
E
M
K
M
V
N
Y
Q
L
I
P
V
N
L
K
K
R
V
L
Y
T
P
E
I
A
E
N
Q
Q
M
I
S
L
L
S
P
F
Q
N
K
G
K
A
Q
L
E
V
34
HHSearch
33.28
13%
-18
- C4 -
-
2Z1K
1
?
C:
[51-119]
-----------------
G
V
A
E
K
L
P
Y
L
L
D
L
G
V
E
A
I
Y
L
---
N
P
V
F
A
---------------
S
T
ANHRYHTVDYFQV--
D
P--------------
I
-
L
-------------------
G
G
N
E
A
L
R
H
L
L
E
V
A
H
A
H
G
V
R
V
-
I
L
D
G
V
F
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
32.90
24%
-7
- C4 -
-
2POZ
-
?
A:
[170-251]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
-
H
V
T
R
R
S
M
S
A
E
A
I
E
L
A
Y
R
R
V
K
-
A
-
V
R
D
A
A
G
P
E
I
E
L
M
V
D
L
S
G
G
L
T
T
D
E
T
I
R
F
C
R
K
I
G
E
L
D
I
C
-------
F
V
E
-
E
P
C
D
P
F
D
N
G
A
L
K
V
I
S
E
Q
I
P
L
---------------------------
37
HHSearch
32.79
11%
3
- C4 -
-
1HT6
5
AMY1_HORVU
A:
[22-92]
-----------------
M
M
M
G
K
V
D
D
I
A
A
A
G
V
T
H
V
W
L
---
P
P
P
S
H
SVSNEGYMPGRLYDI
D
A
---------------
S
---------------
K
-
Y
-------------------
G
N
A
A
E
L
K
S
L
I
G
A
L
H
G
K
G
V
Q
A
-
I
A
D
I
V
I
N
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
32.71
37%
-128
- C4 -
-
4RI0
-
HTRA3_HUMAN
A:
[217-255]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
K
Q
I
K
D
W
K
---
K
R
---
F
-
I
G
I
R
M
R
T
--
I
T
P
S
L
V
D
E
L
K
A
-
S
N
P
D
F
P
E
V
S
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
48
Fugue
32.70
19%
26
- C2 -
-
2BBD
8
?
A:
[1-323]
-----------
G
E
I
Y
T
E
T
L
Q
Q
T
Y
A
W
T
A
-----
G
T
N
I
---
P
I
K
I
P
---------------
R
N
---------------
N
F--------------
I
-
R
-------------------
K
I
R
V
Q
L
I
G
S
I
S
N
S
G
T
A
A
V
T
L
P
S
A
P
F
P
Y
N
L
----
V
Q
--------------
T
F
N
L
S
Y
E
G
S
K
T
L
Y
S
V
S
G
T
G
L
G
I
L
M
Y
Y
---
T
T
K
G
Q
N
P
A
Y
P
---
A
P
---------
G
T
S
--
V
P
A
S
G
S
V
N
L
N
V
M
W
E
F
D
L
A
R
F
P
A
TM
V
Q
N
I
I
L
S
I
L
T
G
Q
A
P
S
G
V
S
I
N
A
S
F
Y
I
T
I
T
Y
E
R
V
T
A
Q
E
I
L
S
E
G
G
L
G
A
D
G
E
M
---
P
--
L
--
A
T
V
L
P
K
V
I
E
I
P
T
F
N
--------
V
P
A
S
-
S
-
A
P
I
H
V
A
Y
L
Q
P
G
Q
I
Y
K
R
Q
L
V
Y
V
I
N
---
S
T
S
G
I
N
N
T
--
D
P
T
E
---
Y
E
L
K
I
-
V
R
G
-
V
-
P
T
D
K
I
K
V
S
W
A
A
L
Q
A
E
N
Q
A
E
Y
-
Q
-
V
--
A
P
Y
S
G
--------
A
S
A
I
I
D
F
R
-
K
Y
--
F
N
G
D
L
D
L
T
HAPSDS
I
E
Y
D
-
L
A
L
Q
N
Q
D
N
V
Y
S
L
Y
V
S
Y
V
L
P
Y
Y
D
Q
L
A
A
L
--------------------
42
Fugue
32.68
20%
-62
- C4 -
-
4UN1
1
?
B:
[21-179]
-------------------------------------------
M
---------------
S
H
---------------
Q
---------------
F
-
S
-------------------
P
E
E
Q
A
V
L
R
I
V
Q
A
N
L
P
D
S
L
T
P
-
Y
A
D
L
A
E
Q
A
----
G
M
--------------
T
E
A
Q
V
L
E
L
L
G
R
L
K
A
S
G
A
I
R
-
R
F
G
-
A
S
---
I
K
H
Q
K
-
T
G
W
T
---
H
N
---
A
M
V
A
W
K
-----
V
T
P
D
Q
V
D
D
C
G
R
-
K
A
A
E
H
S
H
I
S
H
--
V
Y
-
Y
R
P
S
S
A
P
D
W
P
Y
E
--------
M
Y
T
M
I
H
G
R
S
E
A
E
C
L
G
V
V
E
D
V
K
R
T
T
S
L
K
E
H
A
--
I
--
L
R
S
L
K
E
L
K
K
T
S
M
T
Y
F
T
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
HHSearch
32.44
17%
27
- C4 -
-
4AEF
-
?
A:
[241-307]
------------------
I
K
E
K
I
D
H
L
V
N
L
G
I
N
A
I
Y
L
---
T
P
I
F
S
---------------
S
L
TYHGYDIVDYFHV--
A
R--------------
R
-
L
-------------------
G
G
D
R
A
F
V
D
L
L
S
E
L
K
R
F
D
I
K
V
-
I
L
D
G
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------