@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : I3TZX1: (2017-12-17 )
MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFKTRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTEIVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFGVYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGNQPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELDGAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNWIFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFLLVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSDCLLEKFNKEQIIWKNPPTPDDWEYFGNIIIREKNRHLTEKIS
Atome Classification :
(20 SA)
---.........10........20....-....30.--..-.....-40.-....--------...50.......-.60.-----.---.......70.---------------....----------------...80..-....----..90-----------------------------------..-....--..100.-.-..--...110.......120.....-..130----------------....-...140..-.-.-.-...150----.--.......---.160.......170------.....--....--180----....-....190.-.-------.....200---.....---..210.....-..220....-----....230...-....240.----......250-----.......260...---------...-.270...-.....280.----...--...290..-.....300.--......-.---310........320.......330.----......340..----.-.....350........360.......370...-.--...380.......390.....-..-400.......-410-.......420...-....430......----------.440.........-450...-.-...-460.--......470..-....------.480.......490-
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
---MKL
D
Y
L
IEEE
D
R
E
K
L
L
L
A
R
Y
L
E
FEK-K
N
Y
V
V
L
P
--
K
L
-
Y
E
T
LG-LSK-FKTR--------
N
Y
I
I
E
LNK
E
F
T
E-FK-T-----K---P
E
I
Q
ISEEA
E
---------------
I
H
V
E
----------------RL
N
L
T
D
I
-
K
N
L
R
----
R
I
Y
F
-----------------------------------
Q
R
-
S
K
I
A
--
R
L
L
T
E
I
-V-DS--K
V
T
I
E
K
F
A
ENH
F
L
S
I
S
R
A
Y
V
K
-
R
R
E
L
V
----------------
S
F
L
E
-
Q
H
Q
I
K
-
L
K
-K-N-I-LVGE------E--I
N
I
R
N
V
L
---
F
G
V
Y
F
G
V
FNGFS--------M
P
F
R
E
--
S
V
M
N
--
E
A
-----
K
S
I
V
-
Q
Y
F
E
Y
L
FN-L-------KLSA
T
K
R
I
---
K
F
N
L
L
---
T
T
I
S
L
L
R
A
YG-NQ
P
-
I
G
K
R
F-----FS
D
E
YFKSSE-
G
M
K
I
I
K
D
L
----
S
H
I
S
F
LHI
P
-----
K
E
Q
I
I
D
E
I
S
Y
I
M
L
---------
F
L
I
-
T
E
-
E
EFE-LDGAFG
L
A
E
----
A
H
F
--
H
D
I
H
M
I
S
Q
-
K
M
S
V
E
L
-
I
D
--QLP
F
S
I
-
E
---IS-EE
E
R
L
Y
I
R
K
E
L
R
M
G
M
MHVNRK
N
----
W
I
F
D
F
EM-TSF----T-S
K
K
Q
L
Q
-
F
F
F
E
TY
P
I
F
S
T
A
I
Q
K
V
I
Q
ENK
R
Y
FL-G--KD
E
R
F
M
I
R
L
F
Y
D
Y
L
F
L
L
V
G
IC-
P
V
-
S
Y
FEA
P
I
H
V
C
-
I
DF-SQGS
A
Y
T
D
Y
I
I
S
Q
-
V
KGFKN
Y
N
I
V
I
E
S
----------RI--TSRT
N
I
Y
L
S
-
D
C
L
L
E
K-F-NKE-
Q
I
I
W--KNPPTP
D
D
W
E
Y
-
F
G
N
I
------
I
I
REKN
R
H
L
T
E
KIS-
21
HHSearch
65.58
14%
-32
- C3 -
-
4R6I
1
ATXA_BACAN
B:
[4-476]
---
M
L
T
P
I
S
I
E
K
E
H
I
R
L
I
N
L
L
H
F
I
N
E
Q
N
-
R
-
W
F
T
I
K
--
E
L
-
S
D
Y
L
Q
-
V
A
D
-
K
T
V
R
--------
K
Y
L
K
L
L
E
D
E
I
P
P
-
S
W
------------
N
L
L
V
Q
K
G
K
G
---------------
I
Y
L
K
----------------
K
P
L
N
E
S
L
-
S
F
V
E
----
S
K
I
L
-----------------------------------
R
K
-
S
L
N
L
--
Q
I
C
E
E
L
V
F
-
K
K
---
N
S
M
Q
S
L
A
Q
K
L
H
L
Q
V
G
A
L
Y
P
I
-
I
N
Q
I
N
----------------
Y
D
I
Q
-
S
S
H
L
N
-
I
K
-
K
-
K
P
L
E
I
S
G
R
------
E
--
Q
D
V
R
V
F
M
---
L
R
L
Y
C
N
I
-
P
N
D
Y
--------
W
P
F
P
Y
--
I
N
K
Q
--
N
I
-----
T
D
L
I
-
N
K
M
E
K
I
L
N
-
V
-------
Q
M
Y
T
Y
S
K
H
---
K
L
C
V
L
---
F
A
I
T
I
S
R
L
L
S
-
G
N
T
-
I
D
N
V
S
-----
G
L
I
L
V
N
K
N
D
D
-
H
Y
K
T
V
A
S
I
----
T
S
E
L
Q
N
S
F
G
-----
V
T
L
H
E
T
E
I
S
F
L
A
L
---------
A
L
L
-
L
S
L
G
N
S
I
-
T
----
N
K
T
-------
L
--
T
S
Y
K
K
T
I
M
-
P
L
A
K
E
I
-
T
K
--
G
I
E
H
K
L
-
Q
---
L
G
-
I
N
-
Y
---
D
E
S
F
L
T
Y
V
V
L
-
I
I
K
K
----
A
L
D
K
N
F
I
-
Q
Y
Y
----
N
Y
N
I
K
F
I
R
-
H
I
K
Q
R
H
P
N
T
F
N
T
I
Q
E
C
I
S
N
L
N
Y
T
V
Y
-
S
--
H
-
F
D
C
Y
E
I
--
S
L
L
T
M
H
F
E
T
Q
R
-
M
L
--
F
K
N
N
P
K
K
I
Y
-
V
Y
T
-
S
Q
G
C
I
H
R
E
Y
I
S
A
L
-
L
E
K
R
Y
N
G
L
I
K
I
V
R
NTI-----------
D
M
E
I
D
I
I
I
S
-
N
-------------------
E
F
P
T
E
R
D
F
H
E
-
I
K
K
----------------------
46
Fugue
65.19
16%
-284
* C4 *
-
4OWT
-
INT3_HUMAN
A:
[33-498]
--------------
G
G
R
L
L
L
S
T
S
L
D
A
K
D
-
E
L
E
E
R
L
E
--
R
C
M
S
I
V
T
S
M
T
A
G
-
V
S
E
R
--------
E
A
N
D
A
L
N
A
Y
V
C
K
G
L
P
-
Q
-----
H
---
E
E
I
C
L
G
L
F
T
L
---------------
I
L
T
E
----------------
P
A
Q
A
Q
K
C
Y
R
D
L
A
----
L
V
S
R
-----------------------------------
D
G
M
N
I
V
L
--
N
K
I
N
Q
I
-
L
M
E
K
--
Y
L
K
L
Q
D
T
C
R
T
Q
L
V
W
L
V
R
E
L
V
K
-
S
G
V
L
--------------------
G
-
A
D
G
V
C
M
T
F
M
K
-
Q
-
I
-
A
G
G
D
------
V
--
T
A
K
N
I
W
L
---
A
E
S
V
L
D
I
L
T
E
Q
------------
R
E
--
W
V
L
K
--
S
S
-----
I
L
I
A
M
A
V
Y
T
Y
L
R
L
-
I
V
D
HHGT
A
Q
L
Q
A
L
R
Q
K
---
E
V
D
F
-----
C
I
S
L
L
R
E
R
F
M
E
C
L
M
I
G
----------------
R
D
-
L
V
R
L
L
Q
N
V
----
A
R
I
P
E
F
E
L
L
-----
W
K
D
I
I
H
N
P
Q
A
L
-------------------
S
P
Q
-
F
T
G
I
L
Q
L
L
Q
S
R
T
S
R
K
F
--
L
A
C
R
L
T
P
D
M
E
T
K
L
L
F
M
T
S
--
R
V
R
F
G
Q
-
Q
----
K
-
R
Y
Q
D
W
F
Q
R
Q
Y
L
S
T
P
D
S
Q
S
L
R
C
D
----
L
I
R
Y
I
C
G
-
V
V
H
----
P
-
S
N
E
V
L
S
S
D
I
L
P
R
W
A
I
I
G
W
L
L
T
T
C
T
S
------
N
-
V
--
A
A
S
N
A
K
L
A
L
F
Y
D
W
L
F
F
S
P
D
K
D
-
S
I
M
N
I
--
E
P
A
I
L
V
M
H
H
S
M
K
P
H
P
A
I
T
A
T
L
L
D
F
M
C
R
I
I
P
N
F
Y
P
P
L
E
G
----------
H
V
--
R
Q
G
V
F
S
S
L
N
-
H
I
V
E
K
R
-
V
-
L
A
H
L
A
P
L
F
--
D
N
P
K
L
D
K
E
L
R
A
M
L
-----------
R
E
K
---
F
P
E
F
C
S
-
24
HHSearch
63.91
14%
-50
- C3 -
-
5WAY
1
?
A:
[1-493]
-----
M
R
D
L
L
S
K
K
S
H
R
Q
L
E
L
L
E
L
L
F
E
H
K
-
R
-
W
F
H
R
S
--
E
L
-
A
E
L
L
N
-
C
T
E
-
R
A
V
K
--------
D
D
L
S
H
V
K
S
A
F
P
D
-
L
--------------
I
F
H
S
S
T
N
G
---------------
I
R
I
I
----------------
N
T
D
D
S
D
I
-
E
M
V
Y
----
H
H
F
F
-----------------------------------
K
H
-
S
T
H
F
--
S
I
L
E
F
I
F
F
-
N
E
--
G
C
Q
A
E
S
I
C
K
E
F
Y
I
S
S
S
S
L
Y
R
I
-
I
S
Q
I
N
----------------
K
V
I
K
R
Q
F
Q
F
E
-
V
S
-
L
T
P
-
V
Q
I
I
G
N
------
E
--
R
D
I
R
Y
F
F
---
A
Q
Y
F
S
E
K
Y
Y
F
L
E
--------
W
P
F
E
N
--
F
S
S
E
--
P
L
-----
S
Q
L
L
-
E
L
V
Y
K
E
T
S
-
F
-------
P
M
N
L
S
T
H
R
---
M
L
K
L
L
---
L
V
T
N
L
Y
R
I
K
F
-
G
H
F
-
M
E
V
---------------
F
L
M
Q
A
E
G
I
E
G
V
----
A
Q
S
F
E
S
E
Y
N
-----
I
S
L
D
E
E
V
V
C
Q
L
F
V
---------
S
Y
F
-
Q
K
-
M
F
F
I
-
D
E
S
L
-
F
M
K
C
----
V
K
K
--
D
S
Y
V
E
K
S
Y
-
H
L
L
S
D
F
-
I
D
--
Q
I
S
V
K
Y
-
Q
---
I
E
--
I
E
N
---
K
D
N
L
I
W
H
L
H
N
T
---
A
----
H
L
Y
R
Q
E
L
F
T
E
F
ILFD
Q
-
K
G
N
T
I
R
-
N
F
Q
N
I
F
P
K
F
V
S
D
V
K
K
E
L
S
H
Y
L
E
T
L
E
V
C
--
S
S
S
M
M
V
N
H
L
S
Y
T
F
I
T
H
T
K
H
L
V
I
N
L
-
L
Q
N
Q
P
K
L
K
V
L
-
V
M
S
-
N
F
D
Q
Y
H
A
K
F
V
A
E
T
-
L
S
Y
Y
C
S
N
N
F
E
L
E
V
WTELELS
K
E
S
L
E
--
D
S
P
Y
D
I
I
I
S
-
N
F
I
I
P
P
-
I
E
N
K
R
-
L
I
Y
S
--
N
N
I
N
T
V
S
L
I
Y
L
-
L
N
A
M
------
M
F
I
R
L
D
E
--------
23
HHSearch
60.27
14%
-43
- C3 -
-
5WAY
1
?
B:
[1-492]
-----
M
R
D
L
L
S
K
K
S
H
R
Q
L
E
L
L
E
L
L
F
E
H
K
-
R
-
W
F
H
R
S
--
E
L
-
A
E
L
L
N
-
C
T
E
-
R
A
V
K
--------
D
D
L
S
H
V
K
S
A
F
P
D
-
L
--------------
I
F
H
---------------------
R
I
I
----------------
N
T
D
D
S
D
I
-
E
M
V
Y
----
H
H
F
F
-----------------------------------
K
H
-
S
T
H
F
--
S
I
L
E
F
I
F
F
-
N
E
--
G
C
Q
A
E
S
I
C
K
E
F
Y
I
S
S
S
S
L
Y
R
I
-
I
S
Q
I
N
----------------
K
V
I
K
R
Q
F
Q
F
E
-
V
S
-
L
T
P
-
V
Q
I
I
G
N
------
E
--
R
D
I
R
Y
F
F
---
A
Q
Y
F
S
E
K
Y
Y
F
L
E
--------
W
P
F
E
N
--
F
S
S
E
--
P
L
-----
S
Q
L
L
-
E
L
V
Y
K
E
T
S
-
F
-------
P
M
N
L
S
T
H
R
---
M
L
K
L
L
---
L
V
T
N
L
Y
R
I
K
F
-
G
H
F
-
M
E
V
-------------
L
D
F
L
M
Q
A
E
G
I
E
G
V
----
A
Q
S
F
E
S
E
Y
N
-----
I
S
L
D
E
E
V
V
C
Q
L
F
V
---------
S
Y
F
-
Q
K
-
M
F
F
I
-
D
E
S
L
-
F
M
K
C
----
V
K
K
--
D
S
Y
V
E
K
S
Y
-
H
L
L
S
D
F
-
I
D
--
Q
I
S
V
K
Y
-
Q
---
I
E
--
I
E
N
---
K
D
N
L
I
W
H
L
H
N
T
---
A
----
H
L
Y
R
Q
E
L
F
T
E
F
ILFD
Q
-
K
G
N
T
I
R
-
N
F
Q
N
I
F
P
K
F
V
S
D
V
K
K
E
L
S
H
Y
L
E
T
L
E
V
C
--
S
S
S
M
M
V
N
H
L
S
Y
T
F
I
T
H
T
K
H
L
V
I
N
L
-
L
Q
N
Q
P
K
L
K
V
L
-
V
M
S
-
N
F
D
Q
Y
H
A
K
F
V
A
E
T
-
L
S
Y
Y
C
S
N
N
F
E
L
E
V
WTELELS
K
E
S
L
E
--
D
S
P
Y
D
I
I
I
S
-
N
F
I
I
P
P
-
I
E
N
K
R
-
L
I
Y
S
--
N
N
I
N
T
V
S
L
I
Y
L
-
L
N
A
M
------
M
F
I
R
L
D
---------
53
Fugue
50.18
16%
26
- C2 -
-
4D2I
1
HERA_SULSO
A:
[1-476]
---
M
I
I
G
Y
V
I
G
Q
A
T
T
Q
E
A
L
I
L
A
E
R
P
V
R
L
-
G
T
Y
V
V
L
E
Y
-
D
N
-
V
K
A
L
G
-
L
I
T
-
N
V
T
R
G
S
PLLDDN
M
N
D
I
E
I
V
Q
R
L
K
Q
-
F
N
-
N
-----
S
---
I
P
V
Y
T
K
A
K
V
K
---------------
L
L
C
D
MNNHFLMPD
I
P
P
F
AGT
P
A
R
E
A
E
D
-
E
E
L
K
----
S
I
Y
S
-----------------------------------
Q
D
-
G
Q
I
R
IG
S
L
I
G
K
N
-
V
-
E
V
--
K
L
N
I
N
S
F
A
R
-
H
L
A
I
L
A
A
T
G
S
G
-
K
S
N
T
V
----------------
A
V
L
S
-
Q
R
I
S
E
-
L
G
-
G
-
S
-
V
-
L
I
F
D
YHGEYY
D
--
S
D
I
K
N
-----
L
N
R
I
E
P
K
L
N
P
L
Y
--------
M
T
P
R
E
F
S
T
L
L
E
--
I
R
-----
E
N
A
I
-
I
Q
Y
R
I
L
R
R
-
A
-------
F
I
K
V
T
N
G
I
---
R
A
A
L
A
A
GQ
I
P
F
S
T
L
N
S
Q
F
-
Y
E
L
-
M
A
D
A
L
-----
K
D
E
V
L
N
K
F
E
E
-
F
M
D
R
Y
S
N
V
---------
I
D
L
T
-----
S
S
D
I
I
E
K
V
K
R
G
K
V
---------
N
V
V
-
S
L
-
T
Q
L
D
-
E
D
S
M
D
A
V
V
S
----
H
Y
L
--
R
R
I
L
D
S
R
K
-
D
F
K
R
S
K
-
N
S
--
G
L
K
F
P
I
-
I
---
A
V
I
E
E
A
H
V
F
L
S
K
N
------------------------
E
N
T
----
L
-
T
K
Y
W
A
S
-
R
I
A
R
E
G
R
K
F
G
V
G
L
T
I
V
S
Q
R
P
K
G
L
-------
D
E
N
I
L
S
Q
M
T
N
K
I
I
L
K
I
I
E
P
T
-
D
K
-
K
Y
I
L
-----------
E
S
S
D
N
L
S
E
D
L
A
E
Q
-
L
S
S
L
D
V
G
E
A
I
I
I
G
----------
K
I
--
V
K
L
P
A
V
V
K
I
-
D
--------------
M
F
--
E
G
K
L
L
G
S
D
P
D
M
-
I
G
-----------------------
52
Fugue
50.03
18%
-
- C4 -
-
4UVJ
-
SCC3_YEAST
A:
[674-1059]
------------
D
S
V
K
E
I
V
L
P
L
F
Y
D
L
L
N
-
A
A
S
I
L
C
P
--
L
L
-
E
S
F
I
T
-
F
S
E
-
T
E
L
K
--------
K
I
T
D
K
T
I
K
A
F
M
D
-
S
T
-
I
-----
G
---
N
S
-
K
V
D
M
K
Y
D
---------------
I
F
A
K
----------------
F
I
H
H
I
H
H
-
F
E
---------------------------------------------
K
K
-
E
L
Q
E
--
K
F
L
N
Q
I
-
A
-
T
L
--
K
I
H
L
K
K
F
L
Q
E
K
M
D
P
N
N
S
R
D
D
Y
-
K
D
L
T
C
----------------
S
L
Y
E
-
L
Y
----
I
N
-
K
-
L
-
T
-
I
L
G
R
------
D
Y
P
I
E
V
D
E
E
L
---
L
Q
L
F
L
N
N
F
-----------------------------------
V
-
S
R
I
P
I
M
F
Q
D
F
-------
D
D
S
T
A
Q
E
I
---
N
F
K
M
L
---
V
L
L
A
T
W
N
L
E
K
-
W
R
E
-
I
I
E
K
---------------------
V
R
D
L
----
R
S
V
---
W
K
P
-----
I
A
A
I
I
G
R
L
N
T
L
V
I
---------
S
L
A
A
T
N
-
E
T
F
E
N
I
N
S
L
F
Y
L
K
W
----
S
A
C
--
T
S
L
M
D
I
I
V
-
A
I
K
I
F
E
-
L
---
K
L
P
A
D
-------
A
-
T
T
W
R
Y
S
M
S
E
Q
------------------
F
P
F
Y
L
-
H
D
N
----
A
-
S
K
V
L
L
K
-
I
F
L
Y
L
E
S
L
F
A
K
Q
V
D
V
Q
L
E
R
V
A
---------
D
E
D
A
N
L
N
D
L
P
E
T
G
F
-----------------------
F
-
E
N
I
E
T
E
F
L
L
F
T
V
K
-
L
K
G
L
M
K
L
N
I
-
L
D
E
----------
R
F
--
A
S
R
V
A
L
-------------
N
K
E
-
K
L
--------------------------------
G
P
L
F
K
K
I
V
-
48
Fugue
46.02
17%
-94
- C1 -
-
5TC1
-
MATA_BPMS2
M:
[1-393]
---
M
R
A
F
S
T
L
D
R
E
N
E
T
F
V
Y
R
S
N
W
T
-----------
P
--
G
R
-
F
N
S
T
G
--
A
K
-
T
K
Q
W
--------
H
Y
P
S
P
Y
S
R
G
A
L
S
-
V
T
-
S
-----
I
---
F
S
L
D
A
R
S
C
Y
S
---------------
L
F
P
V
----------------
S
Q
N
L
T
Y
I
-
E
V
----------------------------------------------
P
-
Q
N
V
A
--
N
R
A
S
T
E
-
V
-
L
Q
--
K
V
T
Q
G
N
F
------
N
L
G
V
A
L
A
E
-
A
R
S
T
A
----------------
S
Q
L
A
-
T
Q
T
I
A
-
L
V
-
K
-
A
-
Y
-
T
A
A
R
------
R
--
G
N
W
R
Q
A
L
-----
R
Y
L
A
L
N
E
D
-----------------------------------------------------------------------------
R
K
F
R
-
S
K
H
-
V
A
G
R
W
-----
L
E
--------------------------
L
Q
F
G
-----
W
L
P
L
M
S
D
I
Q
G
A
Y
E
---------
M
L
T
-
K
V
----------------------------
H
L
Q
E
-
F
L
P
M
R
A
-
V
R
--
Q
V
G
T
N
I
-
K
---
L
D
-
G
Q
T
T
C
N
I
S
R
R
I
V
I
-
W
F
Y
I
N
D
A
R
----
L
A
W
---
L
-
S
S
L
----
G
-
I
L
N
P
L
G
-
I
V
W
E
K
V
P
F
------------------------
S
F
V
V
D
W
L
L
P
V
G
N
M
L
E
G
L
T
-
A
------------------------
P
V
G
C
S
Y
-
M
S
G
T
V
T
D
V
I
T
G
E
S
----------
I
I
QG
T
A
K
A
Q
I
S
A
M
-
H
R
G
V
Q
S
V
W
-
P
T
T
-
G
A
Y
V
--
K
S
P
---------
F
S
M
V
------
H
T
L
D
A
L
A
L
I
R
Q
R
L
S
R
43
HHSearch
40.79
17%
-238
- C3 -
-
2HEO
1
ZBP1_MOUSE
A:
[9-52]
-------------
D
N
L
E
Q
K
I
L
Q
V
L
S
D
D
G
-
G
-
P
V
A
I
F
--
Q
L
-
V
K
K
C
Q
-
V
P
K
-
K
T
L
N
--------
Q
V
L
Y
R
L
K
K
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
41
HHSearch
38.77
24%
-224
- C3 -
-
1WI9
-
A:
[101-145]
-----------
G
S
S
G
F
L
T
E
F
I
N
Y
I
K
K
S
K
-
V
--
V
L
L
E
--
D
L
-
A
F
Q
M
G
-
L
R
T
-
Q
D
A
I
--------
N
R
I
Q
D
L
L
T
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
50
Fugue
38.23
31%
-245
- C3 -
-
2NPI
-
PCF11_YEAST
C:
[24-45]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
Q
S
R
N
W
Y
L
S
-
D
S
Q
W
A
A
-
F
-
K
D
D
-
E
I
T
----------------------------------------
38
HHSearch
36.82
16%
-205
- C3 -
-
2LNB
-
ZBP1_HUMAN
A:
[19-61]
--------------
H
L
E
Q
R
I
L
Q
V
L
T
E
A
G
-
S
-
P
V
K
L
A
--
Q
L
-
V
K
E
C
Q
-
A
P
K
-
R
E
L
N
--------
Q
V
L
Y
R
M
K
K
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
39
HHSearch
36.69
10%
-109
- C3 -
-
2L4M
-
ZBP1_HUMAN
A:
[109-150]
---------------
R
E
E
D
I
Y
R
F
L
K
D
N
G
-
P
--
Q
R
A
L
--
V
I
-
A
Q
A
L
G
-
M
R
T
A
K
D
V
N
--------
R
D
L
Y
R
M
K
S
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
HHSearch
35.64
16%
-75
- C3 -
-
1P4X
-
SARS_STAA1 (first)
A:
[34-201]
--------------
I
K
E
F
I
L
L
T
Y
L
F
H
Q
Q
-
E
N
T
L
P
F
K
--
K
I
-
V
S
D
L
C
-
Y
K
Q
-
S
D
L
V
--------
Q
H
I
K
V
L
V
K
H
S
Y
I
-
S
K
V
R
S
KI--
D
ER
N
T
Y
I
S
I
S
E
E
Q
R
---------------
E
K
I
A
----------------
E
R
V
T
L
F
D
-
Q
I
I
K
----
Q
F
N
L
A
DQSESQMIPKD
S
K
E
F
L
N
L
M
M
Y
T
M
Y
F
K
N
I
I
K
K
HLT
L
S
-
F
V
E
F
--
T
I
L
A
I
I
T
S
-
Q
N
KN
I
V
L
L
K
D
L
I
E
T
I
H
H
K
Y
P
Q
T
V
R
A
-
L
N
N
L
K
----------------
K
Q
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
49
Fugue
34.82
19%
-72
- C3 -
-
5J6X
-
?
A:
[7-72]
---------
M
S
A
E
N
E
I
E
M
R
I
C
D
Y
L
R
R
H
G
-
R
S
--
T
V
Q
--
D
I
-
F
K
E
L
K
-
L
E
K
-
S
T
V
N
--------
R
H
L
Y
S
L
Q
A
S
K
Q
V
-
F
K
-
T
V
E
D
NK
R
---
P
V
W
D
L
V
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
51
Fugue
34.69
16%
-18
- C2 -
-
4RAP
-
TIBC_ECOH1
A:
[10-391]
---
I
T
P
P
D
T
P
T
Q
A
G
P
E
N
I
----
F
Y
D
F
N
D
-
G
A
R
V
L
L
P
E
G
K
W
-
H
V
R
L
L
-
D
A
D
-
S
E
N
I
--------
L
F
C
C
D
V
D
K
G
W
V
T
-
S
S
-
K
-----
K
---
Y
F
V
R
F
R
I
Q
V
F
---------------
R
Q
G
A
----------------
T
P
L
L
D
E
T
-
L
K
L
K
D
R
P
V
L
I
S
F
-----------------------------------
P
T
-
G
T
L
G
--
D
L
L
G
W
F
-
P
-
Y
A
------
E
R
F
Q
S
L
H
K
C
---
R
L
E
C
T
M
S
Q
D
I
I
----------------
D
L
L
A
-
P
Q
Y
------
P
-
Q
-
I
-
Q
F
S
T
------
P
--
D
K
P
R
T
V
A
---
P
Y
A
T
Y
R
V
----
G
--------
L
Y
F
G
G
--
D
T
N
N
--
Q
P
-----
V
D
--------------------------------------------
F
R
K
V
G
-
F
H
R
-
S
A
G
Y
I
-----
L
G
----
V
D
P
R
-
E
A
P
V
R
L
D
L
----
S
A
P
R
V
I
A
A
P
----------------
Y
V
---------
C
I
A
-
T
Q
-
S
T
C
Q
-
A
K
------------
Y
W
--
N
N
--
G
T
G
W
-
S
E
V
I
A
H
-
L
K
--
S
L
G
Y
R
V
M
C
---
I
D
-
R
D
A
--------
H
Y
G
Q
G
F
V
W
N
H
-------
I
P
W
G
A
-
E
D
F
----
T
-
G
K
L
P
L
Q
-
E
R
V
N
L
L
R
------------
H
A
S
F
F
I
-
G
L
P
S
G
L
S
W
L
A
W
A
T
R
I
P
V
V
L
I
S
G
F
S
L
P
N
-
S
E
F
Y
T
P
W
R
V
F
-
N
S
H
-
G
C
Y
G
C
W
D
D
---------------------------------
T
S
L
N
-------------
F
-
D
H
H
-
D
F
L
W
CP
R
H
K
N
T
D
R
Q
F
E
C
-
T
R
L
I
T
G
A
---
Q
V
N
G
V
I
N
K
L
H
R
S
L
T
-
47
Fugue
34.12
12%
8
* C2 *
-
1C0A
2
SYD_ECOLI
A:
[1-585]
MRT
E
Y
C
G
Q
L
R
L
S
H
V
G
Q
Q
V
T
L
C
G
W
V
N
R
R
R
D
L
G
S
L
I
F
I
--
D
M
-
R
D
R
E
G
-
I
V
Q
-
V
F
F
D
--------
P
D
R
A
D
A
L
K
L
A
S
E
-
L
R
-
N
-----
E
---
F
C
I
Q
V
T
G
T
V
R
A
R
DEKNINRDMATGE
I
E
V
L
----------------
A
S
S
L
T
I
I
-
N
R
A
D
----
V
L
P
L
DSNHVNT----------------------------
E
E
-
A
R
L
K
--
Y
R
Y
L
D
L
-
R
-
R
P
--
E
M
A
Q
R
L
K
T
R
A
K
I
T
S
L
V
R
R
F
M
D
-
D
H
G
F
L
D
I
E
T
P
ML
T
K
A
T
P
E
G
A
R
D
Y
L
V
-
P
S
R
V
H
-
K
G
-
K
-
F
-
Y
-
A
L
P
Q
SP----
Q
--
L
F
K
Q
L
L
M
M
S
G
F
D
R
Y
Y
Q
I
V
K
C
F
R
D
E
D
L
R
ADR
Q
P
E
F
T
--
Q
I
D
V
--
E
T
S
FMT
A
P
Q
V
R
-
E
V
M
E
A
L
V
R
-
H
-------
L
W
L
E
V
K
G
V
DLG
D
F
P
V
M
---
T
F
A
E
A
E
R
R
Y
G
-
S
D
K
-
P
D
L
R
N
P
M
E
L
T
D
V
A
D
L
L
K
S
V
E
-
F
A
V
F
A
G
P
A
N
DPK
G
R
V
A
A
L
R
V
P
GGASL
T
R
K
Q
I
D
E
Y
G
N
F
V
K
I
Y
GAK
G
L
A
Y
I
K
V
-
N
E
-
R
A
K
G
-
L
E
G
I
N
S
P
V
A
----
K
F
L
N
A
E
I
I
E
D
I
L
D
-
R
T
A
A
Q
D
-
G
D
--
M
I
F
F
G
A
-
D
N
K
K
I
V
-
A
D
A
M
G
A
L
R
L
K
V
G
K
D
L
G
L
T
D
E
S
K
W
A
P
L
W
V
I
D
F
P
M
-
F
E
D
----
D
-
G
E
G
G
L
T
-
A
M
H
H
P
F
T
S
P
K
D
M
T
A
A
E
L
K
A
A
P
E
N
A
V
-
A
--
N
--------
A
Y
D
M
V
I
N
G
Y
E
V
G
-
G
G
-
S
V
-----
R
I
H
-
N
G
D
-
M
Q
Q
T
V
F
G
I
L
G
I
N
E
-
E
E
Q
R
E
K
F
G
F
L
L
D
A
L
K
Y
-------
G
T
--
P
P
H
A
G
L
A
F
G
L
D
R
L
T
M
L
-
L
-
T
G
T
-
D
N
I
R
--
D
V
I
A
F
P
K
T
T
A
A
-
A
C
L
M
TEAPSF
A
N
P
T
A
L
A
E
L
S
I
Q
V
V
K
40
HHSearch
30.76
10%
-88
- C3 -
-
3EYI
2
B:
[11-52]
---------------
R
E
E
D
I
Y
R
F
L
K
D
N
G
---
P
Q
R
A
L
--
V
I
-
A
Q
A
L
G
-
M
R
T
A
K
D
V
N
--------
R
D
L
Y
R
M
K
S
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
HHSearch
30.20
10%
-99
* C3 *
-
4KA4
2
E:
[13-55]
--------------
Q
R
E
E
D
I
Y
R
F
L
K
D
N
G
---
P
Q
R
A
L
--
V
I
-
A
Q
A
L
G
-
M
R
T
A
K
D
V
N
--------
R
D
L
Y
R
M
K
S
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
29.44
25%
-34
- C3 -
-
1T1E
-
?
A:
[49-174]
--------------------------------------------------------------------------------------------
Q
R
G
D
E
L
E
---------------
A
H
V
E
----------------
R
Q
A
A
--
L
-
A
P
H
A
----
R
V
H
L
-----------------------------------
E
R
-
E
A
F
A
--
A
S
H
G
A
S
-
L
-
D
D
--
F
A
E
I
R
K
F
A
E
A
H
G
L
T
L
D
R
A
H
V
--------------------------------
A
-
A
G
-
T
-
A
-
V
-
L
S
G
-------
P
--
V
D
A
V
N
Q
A
---
F
G
V
E
L
R
H
F
D
H
P
D
--------
G
S
Y
R
S
--
Y
V
G
D
V
R
V
P
-----
A
S
I
A
-
P
L
I
E
A
V
L
G
-
L
-------
D
T
R
P
V
A
R
P
---
H
F
R
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
28.84
22%
0
- C- -
-
2EFJ
1
DXMT1_COFCA
A:
[199-306]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
F
T
K
D
F
----
T
--
T
F
L
R
I
H
-----
S
E
E
L
I
S
R
G
R
M
L
L
T
---------
F
I
C
-
K
E
-
D
E
F
D
-
H
P
N
S
M
D
L
L
E
----
M
S
I
--
N
D
L
-
V
I
E
G
-
H
L
E
E
E
K
-
L
D
S
F
N
V
P
I
Y
A
-
P
---
S
T
-
E
E
V
K
R
I
V
E
E
E
G
S
F
E
I
L
Y
L
E
T
F
N
----
A
P
Y
D
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------