@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Q3XXW7: (2018-01-06 )
MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGNIVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGIINKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMMAVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLAISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFITFGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFLVMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWGEQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITAYQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF
Atome Classification :
(20 SA)
----.........10........20........30........40.-----....--....50..-......60........70.......-.80......-..90........100.......110.......120-..-......130.-......140.-......150.......160......-----.170.......180.----.----..-..-.190-.-......-.-------.200---.......210.......220.......230.......240.......250.......260.....----..270.......280.......290.......300....-...310.......320-.-..-....330-.......340.---..------....350-.......360..---.....370.......380.......390.....--..--400.......410.......420.......430.......440....-----...450.......460....-...470...-----.-----...480.......490.......500.....
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
----MEQ
T
K
K
K
KFQMP
S
A
Y
T
V
L
F
I
I
I
A
V
I
A
V
L
T
W
F
IPAGHYSVD-D-----AGNI--VAG
S
Y
E
R
V
-QQNP
Q
G
L
W
D
I
F
M
A
PINGMLGVPA
G
E
-LTKETPAA
I
-
P
I
S
F
F
I
L
V
V
G
G
F
L
G
I
INKTGA
L
D
A
G
I
A
S
V
V
K
K
FK--GK-EK
M
L
I
P
V
L
M
L
-
L
F
A
LGGSTYG-MAEET
I
P
F
Y
A
L
L
I
P
V
M
M
A
V
G
F
D
T
V
V
-----
A
V
A
I
V
L
VGSQV
G
C
L
A
----S----TV-
N
P
-
F
A
---
T
-
G
VASQA-V-------GISM---GE
G
I
G
L
R
F
L
M
F
V
I
L
L
A
I
S
I
V
Y
V
Y
R
Y
A
S
K
IEKDP
T
K
S
L
V
Y
N
Q
R
K
E
D
M
K
HF
D
I
E
AI
G
R
Q
E
V
I
T
K
K
QK----H
V
N
V
L
F
F
I
T
F
G
I
M
I
I
SLIPWTTLNA
N
F
T
I
F
E
S
L
T
N
W
L
TN-L
P
V
L
G
T
V
L
GKSMLPLG-D-WY-
F
P
E
I
T
M
L
-
F
L
V
M
S
I
V
V
A
I
T---YG------M
K
E
S
E
F
V
-
S
E
F
L
AG
A
S
D
L
I
G
---
V
A
I
V
V
A
V
A
R
G
I
Q
V
VMNNGL
I
T
D
T
I
L
H
W
G
E
Q
G
L
S
--
S
L--SS
S
V
F
I
I
I
T
F
I
F
Y
I
P
M
S
F
LIPSTSG
L
A
A
A
T
M
GIMGP
M
G
E
F
AGVGK
D
L
-----
V
I
T
A
YQSASG
L
V
N
L
IT
P
T
S
A
-
I
V
M
G
A
V
A
I
A
-----
R
-----
F
D
V
S
V
W
W
K
FT
G
K
L
I
A
I
L
F
V
A
I
C
V
I
L
G
V
A
AMF
8
HHSearch
80.44
20%
-
- C2 -
-
4R1I
-
?
B:
[15-501]
------
T
V
E
W
L
G
N
M
L
P
H
P
V
T
L
F
I
I
F
I
V
L
L
L
I
A
S
A
V
G
A
Y
F
G
L
S
V
P
D
P
RPVGA
K
G
R
A
--
D
D
G
L
I
H
V
V
S
L
L
D
A
D
G
L
I
K
I
L
T
H
T
V
K
N
F
T
G
F
-------------
A
-
P
L
G
T
-
V
L
V
S
L
L
G
V
G
I
A
E
K
S
G
L
I
S
A
L
M
R
L
L
L
T
K
S
P
--
R
K
-
L
T
---
T
F
M
V
V
-
F
T
G
I
L
S
N
T
-
A
-
S
E
L
G
Y
V
V
L
I
P
L
S
A
V
I
F
H
S
L
G
R
H
P
L
A
-----
G
L
A
A
A
F
A
G
V
S
G
G
Y
S
A
NLFL
G
----
T
I
-
D
P
-
L
L
---
A
-
G
I
T
Q
Q
A
-
A
-------
Q
I
I
H
PDY
V
V
G
P
E
A
N
W
F
F
M
A
A
S
T
F
V
I
A
L
I
G
Y
F
V
T
E
K
I
V
-
E
P
Q
L
G
P
-
Y
Q
S
D
L
S
Q
E
E
----
K
D
I
R
H
S
N
E
I
T
P
L
E
Y
K
G
L
I
W
A
G
V
V
F
I
A
L
S
A
L
L
A
W
S
-
I
V
P
A
D
G
I
L
R
H
P
---
E
-
T
G
-----------
L
-
V
A
-
G
S
P
F
L
-
K
-
S
I
-
V
V
F
I
F
L
L
-
F
A
L
P
G
I
V
Y
G
R
I
---
T
R
SL----
R
G
E
R
E
V
V
-
N
A
M
A
E
S
M
S
T
L
G
L
---
Y
L
V
I
I
F
F
A
A
Q
F
V
A
F
F
N
W
T
N
I
G
Q
Y
I
A
V
K
G
A
V
F
L
K
--
E
V
GL
A
G
S
V
L
F
I
G
F
I
L
I
C
A
F
I
N
L
M
I
G
S
A
S
A
Q
W
A
V
T
A
P
I
F
V
P
M
L
M
L
A
G
Y
A
P
E
V
-----
I
Q
A
A
Y
R
I
G
D
S
V
T
N
I
I
T
P
M
M
S
-
Y
F
G
L
I
M
A
T
V
M
K
YKK
D
-----
A
G
V
G
T
L
I
S
M
M
L
P
Y
S
A
F
F
L
I
A
W
I
A
L
F
C
-----
9
HHSearch
79.93
20%
-
- C2 -
-
4R1I
-
?
A:
[15-501]
------
T
V
E
W
L
G
N
M
L
P
H
P
V
T
L
F
I
I
F
I
V
L
L
L
I
A
S
A
V
G
A
Y
F
G
L
S
V
P
D
P
R
P
V
G
A
K
G
R
A
--
D
D
G
L
I
H
V
V
S
L
L
D
A
D
G
L
I
K
I
L
T
H
T
V
K
N
F
T
G
F
-------------
A
-
P
L
G
T
-
V
L
V
S
L
L
G
V
G
I
A
E
K
S
G
L
I
S
A
L
M
R
L
L
L
T
K
S
P
--
R
K
-
L
T
---
T
F
M
V
V
-
F
T
G
I
L
S
N
T
-
A
-
S
E
L
G
Y
V
V
L
I
P
L
S
A
V
I
F
H
S
L
G
R
H
P
L
A
-----
G
L
A
A
A
F
A
G
V
S
G
G
Y
S
A
NLFL
G
----
T
I
-
D
P
-
L
L
---
A
-
G
I
T
Q
Q
A
-
A
-------
Q
I
I
H
PD
Y
V
V
G
P
E
A
N
W
F
F
M
A
A
S
T
F
V
I
A
L
I
G
Y
F
V
T
E
K
I
V
-
E
P
Q
L
G
P
-
Y
Q
S
D
L
S
Q
E
E
----
K
D
I
R
H
S
N
E
I
T
P
L
E
Y
K
G
L
I
W
A
G
V
V
F
I
A
L
S
A
L
L
A
W
S
-
I
V
P
A
D
G
I
L
R
H
P
---
E
-
T
G
-----------
L
-
V
A
-
G
S
P
F
L
-
K
-
S
I
-
V
V
F
I
F
L
L
-
F
A
L
P
G
I
V
Y
G
R
I
---
T
R
SL----
R
G
E
R
E
V
V
-
N
A
M
A
E
S
M
S
T
L
G
L
---
Y
L
V
I
I
F
F
A
A
Q
F
V
A
F
F
N
W
T
N
I
G
Q
Y
I
A
V
K
G
A
V
F
L
K
--
E
V
GL
A
G
S
V
L
F
I
G
F
I
L
I
C
A
F
I
N
L
M
I
G
S
A
S
A
Q
W
A
V
T
A
P
I
F
V
P
M
L
M
L
A
G
Y
A
P
E
V
-----
I
Q
A
A
Y
R
I
G
D
S
V
T
N
I
I
T
P
M
M
S
-
Y
F
G
L
I
M
A
T
V
M
K
Y
KK
D
-----
A
G
V
G
T
L
I
S
M
M
L
P
Y
S
A
F
F
L
I
A
W
I
A
L
F
C
-----
11
HHSearch
74.03
14%
-119
- C2 -
-
4R0C
2
?
D:
[10-480]
------
R
L
E
Q
L
G
N
R
L
P
H
P
T
L
L
F
V
W
F
C
L
L
L
L
P
L
T
A
V
L
G
--
A
L
D
V
T
-
A
-----
T
H
P
L
TD
E
T
I
T
A
H
S
L
--
L
D
A
D
G
L
R
Y
L
F
T
T
L
V
G
N
F
T
G
-------------
F
A
-
P
L
G
-
V
V
L
V
A
M
L
G
L
G
V
A
E
Q
S
G
L
L
S
V
S
L
A
S
L
V
R
R
S
S
--
G
G
-
A
---
L
V
F
T
V
A
-
F
A
G
V
L
S
S
L
-
T
-
V
D
A
G
Y
V
V
L
I
P
L
A
G
L
V
F
Q
L
A
G
R
P
P
I
A
-----
G
I
A
T
A
F
A
A
V
S
G
G
F
S
A
----
N
LLVG
P
V
-
D
A
-
T
L
---
A
-
G
L
S
T
E
A
-
A
H
I
IDPD
R
T
V
A
A
---
T
G
N
Y
W
F
I
I
A
S
T
F
L
V
-
T
G
L
V
T
L
I
T
R
T
L
T
E
P
R
L
--
A
H
---
A
N
T
V
A
D
A
S
----
V
D
A
P
Q
I
H
S
R
A
M
K
W
T
G
----
L
T
L
A
I
L
L
A
G
L
A
L
L
V
L
P
---
N
D
A
P
L
R
H
-------------------------
P
-
D
T
G
-
S
V
L
G
-
S
P
F
I
H
G
L
-
V
V
I
V
A
L
I
A
G
I
C
G
A
V
Y
G
R
V
S
GQF
R
N
S
G
A
V
I
-
T
A
M
E
V
T
M
A
S
M
A
G
---
Y
L
V
L
M
F
F
A
A
Q
F
V
A
W
F
N
Y
S
Q
L
G
L
L
L
A
V
K
G
A
A
W
L
G
A
L
T
V
--
P
K
V
V
L
L
L
L
F
V
V
L
T
A
L
I
N
L
M
I
G
S
A
S
A
K
W
S
I
L
A
P
V
F
I
P
M
L
M
L
L
G
I
S
P
E
A
-----
S
Q
A
A
Y
R
V
G
D
S
S
T
N
I
I
T
P
L
M
P
-
Y
F
V
L
V
L
G
F
A
-----
R
R
Y
QPE
T
G
I
G
T
L
I
A
L
M
L
P
Y
S
L
T
L
L
L
G
W
S
V
L
L
------
10
HHSearch
71.33
14%
-116
- C2 -
-
4R0C
5
?
C:
[19-480]
---------------
P
H
P
T
L
L
F
V
W
F
C
L
L
L
L
P
L
T
A
V
L
G
--
A
L
D
V
T
-
A
-----
T
H
P
L
TD
E
T
I
T
A
H
S
L
--
L
D
A
D
G
L
R
Y
L
F
T
T
L
V
G
N
F
T
G
-------------
F
A
-
P
L
G
-
V
V
L
V
A
M
L
G
L
G
V
A
E
Q
S
G
L
L
S
V
S
L
A
S
L
V
R
R
S
S
--
G
G
-
A
---
L
V
F
T
V
A
-
F
A
G
V
L
S
S
L
-
T
-
V
D
A
G
Y
V
V
L
I
P
L
A
G
L
V
F
Q
L
A
G
R
P
P
I
A
-----
G
I
A
T
A
F
A
A
V
S
G
G
F
S
A
----
N
LLVG
P
V
-
D
A
-
T
L
---
A
-
G
L
S
T
E
A
-
A
H
I
IDPD
R
T
V
A
A
---
T
G
N
Y
W
F
I
I
A
S
T
F
L
V
-
T
G
L
V
T
L
I
T
R
T
L
T
E
P
R
L
--
A
H
---
A
N
T
V
A
D
A
S
----
V
D
A
P
Q
I
H
S
R
A
M
K
W
T
G
----
L
T
L
A
I
L
L
A
G
L
A
L
L
V
L
P
---
N
D
A
P
L
R
H
-------------------------
P
-
D
T
G
-
S
V
L
G
-
S
P
F
I
H
G
L
-
V
V
I
V
A
L
I
A
G
I
C
G
A
V
Y
G
R
V
S
GQF
R
N
S
G
A
V
I
-
T
A
M
E
V
T
M
A
S
M
A
G
---
Y
L
V
L
M
F
F
A
A
Q
F
V
A
W
F
N
Y
S
Q
L
G
L
L
L
A
V
K
G
A
A
W
L
G
A
L
T
V
--
P
K
V
V
L
L
L
L
F
V
V
L
T
A
L
I
N
L
M
I
G
S
A
S
A
K
W
S
I
L
A
P
V
F
I
P
M
L
M
L
L
G
I
S
P
E
A
-----
S
Q
A
A
Y
R
V
G
D
S
S
T
N
I
I
T
P
L
M
P
-
Y
F
V
L
V
L
G
F
A
-----
R
R
YQPE
T
G
I
G
T
L
I
A
L
M
L
P
Y
S
L
T
L
L
L
G
W
S
V
L
L
------
12
HHSearch
69.09
14%
-140
- C2 -
-
5ULD
1
?
C:
[77-440]
----------------------------------------------------------------------------------------------------
N
-
S
I
I
F
L
F
L
G
G
F
A
L
A
A
A
M
H
H
Q
G
L
D
K
V
I
A
D
K
V
L
A
M
A
Q
--
G
K
-
M
S
V
A
V
F
M
L
F
G
-
V
T
A
L
L
S
M
W
I
S
-
N
T
A
T
A
A
M
M
L
P
L
V
L
G
V
L
S
K
V
D
A
D
K
Q
R
STYVF
V
L
L
G
V
A
Y
S
A
S
I
G
G
I
A
----
T
----
L
V
G
T
G
-
P
N
---
A
-
I
A
A
A
-
E
-
V
-------
G
L
S
F
---
T
D
W
M
K
F
G
L
P
T
A
M
M
M
L
P
M
A
I
A
I
L
Y
F
L
L
K
P
T
L
N
G
-
M
F
------
E
L
--
D
--------
R
A
P
V
N
W
D
K
G
K
V
----
V
T
L
G
I
F
G
L
T
V
F
L
W
I
F
S
S
P
I
N
-------------------------------
A
-
A
L
G
-
G
-
F
K
S
F
D
T
L
V
A
L
-
G
A
I
--
L
M
L
S
F
A
---
R
V
------
V
H
W
K
E
I
Q
-
K
T
A
D
------
W
G
---
I
L
L
L
F
G
G
G
L
C
L
S
N
V
L
K
Q
T
G
T
S
V
F
L
A
N
A
L
S
D
M
V
S
--
H
M
--
G
I
F
V
V
I
L
V
V
A
T
F
V
V
F
L
T
E
F
-
T
S
N
V
A
T
T
T
L
L
I
P
V
F
A
T
V
A
E
A
F
G
M
S
P
V
L
-----
L
S
V
L
I
A
V
A
A
S
C
A
-
F
M
L
P
V
A
T
P
P
N
A
I
V
F
A
S
G
-----
H
-----
I
K
Q
S
E
M
M
R
V
G
L
Y
L
N
I
A
C
I
G
L
L
T
A
I
A
------
13
HHSearch
68.87
14%
-140
- C2 -
-
5ULE
1
?
C:
[77-440]
----------------------------------------------------------------------------------------------------
N
-
S
I
I
F
L
F
L
G
G
F
A
L
A
A
A
M
H
H
Q
G
L
D
K
V
I
A
D
K
V
L
A
M
A
Q
--
G
K
-
M
S
V
A
V
F
M
L
F
G
-
V
T
A
L
L
S
M
W
I
S
-
N
T
A
T
A
A
M
M
L
P
L
V
L
G
V
L
S
K
V
D
A
D
K
Q
R
STYVF
V
L
L
G
V
A
Y
S
A
S
I
G
G
I
A
----
T
----
L
V
G
T
G
-
P
N
---
A
-
I
A
A
A
-
E
-
V
-------
G
L
S
F
---
T
D
W
M
K
F
G
L
P
T
A
M
M
M
L
P
M
A
I
A
I
L
Y
F
L
L
K
P
T
L
N
G
-
M
F
------
E
L
--
D
--------
R
A
P
V
N
W
D
K
G
K
V
----
V
T
L
G
I
F
G
L
T
V
F
L
W
I
F
S
S
P
I
N
-------------------------------
A
-
A
L
G
-
G
-
F
K
S
F
D
T
L
V
A
L
-
G
A
I
--
L
M
L
S
F
A
---
R
V
------
V
H
W
K
E
I
Q
-
K
T
A
D
------
W
G
---
I
L
L
L
F
G
G
G
L
C
L
S
N
V
L
K
Q
T
G
T
S
V
F
L
A
N
A
L
S
D
M
V
S
--
H
M
--
G
I
F
V
V
I
L
V
V
A
T
F
V
V
F
L
T
E
F
-
T
S
N
V
A
T
T
T
L
L
I
P
V
F
A
T
V
A
E
A
F
G
M
S
P
V
L
-----
L
S
V
L
I
A
V
A
A
S
C
A
-
F
M
L
P
V
A
T
P
P
N
A
I
V
F
A
S
G
-----
H
-----
I
K
Q
S
E
M
M
R
V
G
L
Y
L
N
I
A
C
I
G
L
L
T
A
I
A
------
24
Fugue
62.03
19%
-31
- C1 -
-
4Q8G
-
PAN2_YEAST
A:
[52-454]
TSDI
Q
T
Y
T
S
I
N
K
Y
E
V
P
P
A
Y
S
R
L
--------------
P
L
T
F
D
F
T
P
-
F
-----
N
N
T
E
--
Y
S
G
L
D
P
D
V
-
D
N
H
Y
T
N
A
I
I
Q
L
Y
R
F
I
P
E
M
F
N
F
V
V
G
C
-
L
-
K
D
T
T
L
L
T
-
D
L
G
Y
L
F
D
M
M
E
R
S
H
G
K
I
C
S
S
S
N
F
Q
A
S
L
K
S
L
T
S
I
K
R
--
N
---------
M
P
Q
-
K
F
N
R
F
L
L
S
Q
L
-
I
K
E
E
A
Q
T
V
N
H
N
-
I
T
L
N
Q
C
F
G
L
E
T
E
I
-----
R
T
E
C
--------------------
S
C
-
D
H
-
Y
D
---
T
--------------------------------
T
V
K
L
L
P
S
L
S
I
-------
S
G
I
N
Q
N
I
L
P
Y
I
E
Y
A
M
K
N
V
T
Q
K
N
S
I
C
P
T
C
G
K
T
E
T
I
T
Q
E
C
T
----
V
K
N
L
P
S
V
L
S
L
E
L
--------
S
L
L
D
T
E
F
S
N
I
R
S
S
K
N
W
L
T
S
-
E
F
Y
G
S
I
I
K
N
K
A
V
L
R
--------------------------------------
S
T
A
S
E
------
L
K
G
T
S
H
I
F
K
---
Y
E
L
N
G
Y
V
A
K
I
T
D
N
N
N
E
T
R
L
V
T
Y
V
K
K
Y
N
P
K
E
N
-----------
C
F
K
W
L
M
F
N
D
Y
-----
L
V
V
E
I
T
E
E
E
A
L
K
M
T
Y
-------------------------------
P
W
K
T
P
E
I
I
-
I
Y
C
D
A
E
E
L
R
-----
K
---------------------------------
P
F
F
23
Fugue
61.17
16%
-71
* C1 *
-
5GOO
2
?
A:
[11-457]
---S
L
R
E
T
E
S
W
K
L
L
E
S
S
I
I
Y
Y
E
G
N
P
I
G
T
V
A
A
Q
D
P
E
L
A
A
L
N
Y
D
Q
C
-
F
-----
L
R
D
F
--
V
P
S
A
F
V
F
L
M
D
-
G
Q
T
D
I
V
R
N
F
L
I
E
T
L
T
L
Q
S
-
H
E
K
E
M
D
C
F
Q
P
G
A
G
L
M
P
A
S
F
K
V
E
S
D
G
S
K
E
Y
L
V
A
D
F
G
E
----------
K
A
I
--
A
R
-
V
P
---
P
V
D
S
C
M
W
W
I
L
L
L
R
A
Y
E
-
K
A
T
G
D
L
---
T
L
A
R
E
P
K
F
Q
A
G
I
K
L
I
L
-----
D
L
C
L
---------------
A
----
H
R
-
F
S
M
Y
P
---
T
M
L
V
P
D
G
A
-
F
M------
I
D
R
R
M--
G
--
V
Y
E
H
P
L
E
I
Q
V
L
F
Y
A
A
L
R
A
A
R
E
L
---
L
L
P
D
G
D
G
E
Q
Y
L
N
K
V
H
G
R
L
G
A
L
Q
Y
H
I
R
N
Y
Y
W
V
D
L
K
R
L
R
----
E
I
Y
R
Y
K
G
N
E
F
G
K
E
I
A
--------
N
K
F
N
I
F
S
Q
S
I
P
D
W
V
I
E
W
L
P
E
K
G
G
Y
L
A
G
N
L
G
P
G
R
M
D
-
F
R
-
F
F
A
L
G
N
L
M
A
I
L
A
G
L
A
--------
S
------
E
E
E
S
Q
R
I
M
N
L
F
A
H
R
W
E
D
L
I
G
YMP
V
K
I
C
Y
P
A
L
Q
G
L
E
W
Q
I
V
T
G
C
D
P
K
N
I
------
P
W
S
--
Y
H
--
N
G
G
N
W
P
V
L
L
W
L
F
T
--
A
A
A
L
K
T
G
K
V
E
L
A
H
E
A
I
A
I
A
E
G
R
-----
L
S
N
D
K
-----
F
P
E
Y
Y
D
G
N
N
G
R
---
L
I
G
K
E
A
-
R
I
Y
Q
T
W
S
I
A
-----
G
-----
L
L
V
A
K
Q
F
L
A
N
P
D
H
V
E
F
I
S
-------------
19
HHSearch
48.27
16%
-181
* C2 *
-
4R0C
-
?
D:
[334-477]
---------------------------------------------------------------------------------------------------
M
A
-
G
Y
L
V
L
M
F
F
A
A
Q
F
V
A
W
F
N
Y
S
Q
L
G
L
L
L
A
V
K
G
A
A
W
L
G
A
L
T
V
P
K
V
V
L
L
L
L
F
V
V
-
L
T
A
L
I
N
L
M
I
G
S
A
S
A
K
W
S
I
L
A
P
V
F
I
P
M
L
M
L
L
G
I
S
P
E
A
-----
S
Q
A
A
Y
R
V
G
D
S
S
T
N
I
I
----
T
----
P
L
-
M
P
-
Y
F
V
L
V
L
-
G
F
A
R
R
Y
Q
P
-------
E
T
G
I
---
G
T
L
I
A
L
M
L
P
Y
S
L
T
L
L
L
G
W
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
HHSearch
47.56
16%
-183
- C2 -
-
4R0C
-
?
C:
[334-477]
---------------------------------------------------------------------------------------------------
M
A
-
G
Y
L
V
L
M
F
F
A
A
Q
F
V
A
W
F
N
Y
S
Q
L
G
L
L
L
A
V
K
G
A
A
W
L
G
A
L
T
V
P
K
V
V
L
L
L
L
F
V
V
-
L
T
A
L
I
N
L
M
I
G
S
A
S
A
K
W
S
I
L
A
P
V
F
I
P
M
L
M
L
L
G
I
S
P
E
A
-----
S
Q
A
A
Y
R
V
G
D
S
S
T
N
I
I
----
T
----
P
L
-
M
P
-
Y
F
V
L
V
L
-
G
F
A
R
R
Y
Q
P
-------
E
T
G
I
---
G
T
L
I
A
L
M
L
P
Y
S
L
T
L
L
L
G
W
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
39.57
13%
-168
- C2 -
-
5ULD
1
?
C:
[64-217]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
I
------
F
E
T
Q
A
A
L
-
N
N
F
A
------
N
S
---
I
I
F
L
F
L
G
G
F
A
L
A
A
A
M
H
H
Q
G
L
D
K
V
I
A
D
K
V
L
A
M
A
Q
--
G
---
K
M
S
V
A
V
F
M
L
F
G
V
T
A
L
L
S
M
W
I
-
S
N
T
A
T
A
A
M
M
L
P
L
V
L
G
V
L
S
K
V
D
A
D
K
Q
R
STYVF
V
L
L
G
V
A
Y
S
A
S
I
G
G
I
A
T
L
V
G
T
G
P
N
A
I
A
A
A
E
V
-----
G
-----
L
S
F
T
D
W
M
K
F
G
L
P
T
A
M
M
M
L
P
M
A
I
A
--------
5
PsiBlast_PDB
37.76
31%
-241
- C3 -
-
5K5U
-
?
A:
[310-361]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
L
Y
F
K
L
R
I
N
W
F
K
N
-
S
S
L
I
E
S
I
L
G
K
T
R
M
P
L
D
-
H
-
E
Y
-
Y
K
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
37.74
13%
-173
- C2 -
-
5ULE
1
?
C:
[64-217]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
I
------
F
E
T
Q
A
A
L
-
N
N
F
A
------
N
S
---
I
I
F
L
F
L
G
G
F
A
L
A
A
A
M
H
H
Q
G
L
D
K
V
I
A
D
K
V
L
A
M
A
Q
--
G
---
K
M
S
V
A
V
F
M
L
F
G
V
T
A
L
L
S
M
W
I
-
S
N
T
A
T
A
A
M
M
L
P
L
V
L
G
V
L
S
K
V
D
A
D
K
Q
R
STYVF
V
L
L
G
V
A
Y
S
A
S
I
G
G
I
A
T
L
V
G
T
G
P
N
A
I
A
A
A
E
V
-----
G
-----
L
S
F
T
D
W
M
K
F
G
L
P
T
A
M
M
M
L
P
M
A
I
A
--------
4
PsiBlast_PDB
35.37
31%
-210
- C3 -
-
5HYY
-
?
A:
[310-360]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
L
Y
F
K
L
R
I
N
W
F
K
N
-
S
S
L
I
E
S
I
L
G
K
T
R
M
P
L
D
-
H
-
E
Y
-
Y
K
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
34.45
31%
-186
- C3 -
-
5K5V
-
?
A:
[310-358]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
L
Y
F
K
L
R
I
N
W
F
K
N
-
S
S
L
I
E
S
I
L
G
K
T
R
M
P
L
D
-
H
-
E
Y
-
Y
K
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
Fugue
34.22
10%
-165
- C2 -
-
4C7N
-
A:
[2-48]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
S
V
D
Y
I
R
K
L
Q
R
E
Q
Q
R
A
K
E
L
E
N
R
Q
K
K
L
E
H
A
N
R
H
L
L
L
R
I
Q
E
L
E
M
Q
A
R
----
A
H
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
Fugue
33.52
12%
-175
- C2 -
-
1KIL
-
CPLX1_RAT
E:
[9-49]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
K
E
E
E
R
Q
E
A
L
R
Q
A
E
E
E
R
K
A
K
Y
A
K
M
E
A
E
R
E
----
V
M
R
Q
G
I
R
D
K
Y
G
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
32.13
31%
-186
* C3 *
-
5K61
-
?
A:
[310-358]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
L
Y
F
K
L
R
I
N
W
F
K
N
-
S
S
L
I
E
S
I
L
G
K
T
R
M
P
L
D
-
H
-
E
Y
-
Y
K
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
30.05
31%
-205
- C3 -
-
5B62
-
?
A:
[310-363]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
L
Y
F
K
L
R
I
N
W
F
K
N
-
S
S
L
I
E
S
I
L
G
K
T
R
M
P
L
D
-
H
-
E
Y
-
Y
K
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
Fugue
28.13
25%
41
- C2 -
-
1A93
2
B:
[1-32]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
C
G
G
M
R
R
K
N
D
T
H
Q
Q
D
I
D
D
L
K
R
Q
N
A
L
L
E
Q
Q
V
----
R
A
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------