@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Q3XZY4: (2018-01-17 )
MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALSSIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQADDYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISETLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSRFIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEITQMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKPQGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYMFISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFSQSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPKEYRTQLFLKNKNN
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70--........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
M
Y
K
V
F
I
I
E
D
E
Y
L
I
R
N
N
L
R
E
Q
I
T
VLGSYY
P
I
T
Y
V
GEAGD
G
E
M
A
L
S
S
I
IDLQP
D
I
I
L
T
DIQM
P
F
MDGLT
F
S
K
E
--
A
R
K
LLP
W
T
R
L
I
F
I
SGFDD
F
D
YMK
G
A
I
Q
V
QAD
D
Y
L
LKPI
K
S
S
E
L
K
Q
A
I
E
K
A
V
T
A
L
D
L
Q
QKETHTSS
D
L
V
F
E
L
K
K
N
H
F
L
N
G
L
FKGS
L
T
I
S
E
T
L
K
L
A
E
S
F
N
R
S
LAG
K
K
M
T
V
L
L
AANQVS
T
D
F
E
D
Y
A
H
L
S
D
Y
L
K
F
L
F
RE
N
Q
Q
V
I
F
S
A
V
S
S
R
F
I
K
F
L
IV
D
S
L
E
E
N
V
I
E
T
S
Y
Q
V
A
Q
T
L
V
H
E
L
E
KGQKNN
F
S
V
A
I
G
P
V
A
E
R
I
S
ELPA
S
F
E
I
T
Q
M
I
L
E
T
A
S
S
L
K
E
Q
I
I
S
Y
E
D
L
I
Q
E
AKLPV
D
S
V
F
Y
F
D
L
S
L
D
L
S
SL
S
K
N
E
V
S
K
Y
I
E
H
LTKPQGT
P
T
R
T
R
L
Y
R
L
F
V
L
T
K
L
L
Q
H
V
C
L
K
E
KKI
P
Q
E
M
V
H
CTSTS
Q
R
L
A
ISAD
D
S
L
Y
R
S
T
V
Y
M
F
I
S
F
L
T
ALPSQPSRNK
Y
Q
P
I
L
N
H
A
L
D
F
I
K
ENFTDPD
M
S
L
T
W
V
A
Q
Q
VALS
P
S
H
F
S
T
I
F
S
Q
SF
N
Q
T
F
I
D
Y
L
T
E
Q
R
I
E
L
A
K
K
L
L
Q
QSDY
R
I
S
D
I
A
F
E
I
GYND
P
N
Y
F
S
Y
L
F
K
KKQGI
S
P
K
E
Y
R
T
Q
L
F
L
KNKNN
72
Fugue
75.87
16%
-109
- C1 -
-
1NY5
3
?
A:
[1-384]
-
M
N
V
L
V
I
E
D
D
K
V
F
R
G
L
L
E
E
Y
L
S
M
K
G
I
-----
K
V
E
S
A
E
R
G
K
E
A
Y
K
L
L
S
E
K
H
F
N
V
V
L
L
D
L
L
L
P
D
V
N
G
L
E
I
L
K
W
--
I
K
E
R
S
P
E
T
E
V
I
V
I
T
G
H
G
T
I
K
T
A
V
E
A
M
K
M
G
A
Y
D
F
L
T
K
P
C
M
L
E
E
I
E
L
T
I
N
K
A
I
E
H
R
K
L
R
K
E
N
E
L
L
R
R
E
K
D
L
K
----------
E
E
E
Y
V
F
E
S
P
K
M
K
E
I
L
E
K
I
K
K
I
S
C
A
E
C
P
V
L
I
T
G
--------------------------------
E
S
G
V
G
K
E
V
V
A
R
L
I
H
K
L
S
D
R
S
K
E
P
F
V
A
L
N
V
----------------------
A
S
I
P
R
D
I
F
E
A
E
L
F
G
Y
E
K
G
A
F
T
G
A
V
S
S
K
E
G
F
F
E
L
A
D
---
G
G
T
L
F
L
D
---
E
I
G
E
L
S
L
E
A
Q
A
K
L
L
R
V
I
E
S
G
K
F
Y
R
L
G
G
------------------
R
K
E
I
E
V
N
V
R
I
L
A
A
T
N
R
N
I
K
E
L
V
K
E
G
K
F
R
E
D
L
Y
Y
R
L
G
V
I
E
I
E
----------------
I
P
P
L
R
E
R
K
E
D
I
I
P
L
A
N
H
F
L
K
K
F
S
R
K
Y
A
K
E
V
E
G
F
T
K
S
A
Q
E
L
L
L
S
Y
P
W
Y
G
N
V
R
E
L
K
N
V
I
E
R
A
V
L
F
S
E
G
--------------------
K
F
I
D
R
G
E
L
S
C
L
V
-------
9
PsiBlast_PDB
52.91
33%
-142
- C1 -
-
1TMY
-
CHEY_THEMA
A:
[4-117]
--
R
V
L
I
V
D
D
A
A
F
M
R
M
M
L
K
D
I
I
T
K
A
G
--
Y
E
V
A
--
G
E
A
T
N
G
R
E
A
V
E
K
Y
K
E
L
K
P
D
I
V
T
M
D
I
T
M
P
E
M
N
G
I
D
A
I
K
E
--
I
M
K
I
D
P
N
A
K
I
I
V
C
S
A
M
G
Q
Q
A
M
V
I
E
A
I
K
A
G
A
K
D
F
I
V
K
P
F
Q
P
S
R
V
V
E
A
L
N
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
52.18
33%
-127
- C1 -
-
3TMY
-
CHEY_THEMA
A:
[4-117]
--
R
V
L
I
V
D
D
A
A
F
M
R
M
M
L
K
D
I
I
T
K
A
G
--
Y
E
V
A
--
G
E
A
T
N
G
R
E
A
V
E
K
Y
K
E
L
K
P
D
I
V
T
M
D
I
T
M
P
E
M
N
G
I
D
A
I
K
E
--
I
M
K
I
D
P
N
A
K
I
I
V
C
S
A
M
G
Q
Q
A
M
V
I
E
A
I
K
A
G
A
K
D
F
I
V
K
P
F
Q
P
S
R
V
V
E
A
L
N
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
82
HHSearch
52.13
35%
-162
- C1 -
-
3LSG
-
?
E:
[3-97]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
K
E
L
I
Q
N
I
I
E
E
S
Y
T
D
S
Q
F
T
L
S
V
L
S
E
K
L
D
L
S
S
G
Y
L
S
I
M
F
K
K
N
F
G
I
P
F
Q
D
Y
L
L
Q
K
R
M
E
K
A
K
L
L
L
L
T
T
E
L
K
N
Y
E
I
A
E
Q
V
G
F
E
D
V
N
Y
F
I
T
K
F
K
K
Y
Y
Q
I
T
---------------
5
PsiBlast_PDB
51.88
33%
-120
- C1 -
-
4IGA
-
CHEY_THEMA
A:
[7-120]
--
R
V
L
I
V
D
D
A
A
F
M
R
M
M
L
K
D
I
I
T
K
A
G
--
Y
E
V
A
--
G
E
A
T
N
G
R
E
A
V
E
K
Y
K
E
L
K
P
D
I
V
T
M
D
I
T
M
P
E
M
N
G
I
D
A
I
K
E
--
I
M
K
I
D
P
N
A
K
I
I
V
C
S
A
M
G
Q
Q
A
M
V
I
E
A
I
K
A
G
A
K
D
F
I
V
K
P
F
Q
P
S
R
V
V
E
A
L
N
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
51.84
33%
-120
- C1 -
-
4TMY
-
CHEY_THEMA
A:
[4-117]
--
R
V
L
I
V
D
D
A
A
F
M
R
M
M
L
K
D
I
I
T
K
A
G
--
Y
E
V
A
--
G
E
A
T
N
G
R
E
A
V
E
K
Y
K
E
L
K
P
D
I
V
T
M
D
I
T
M
P
E
M
N
G
I
D
A
I
K
E
--
I
M
K
I
D
P
N
A
K
I
I
V
C
S
A
M
G
Q
Q
A
M
V
I
E
A
I
K
A
G
A
K
D
F
I
V
K
P
F
Q
P
S
R
V
V
E
A
L
N
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
51.17
33%
-142
- C1 -
-
2TMY
-
CHEY_THEMA
A:
[4-117]
--
R
V
L
I
V
D
D
A
A
F
M
R
M
M
L
K
D
I
I
T
K
A
G
--
Y
E
V
A
--
G
E
A
T
N
G
R
E
A
V
E
K
Y
K
E
L
K
P
D
I
V
T
M
D
I
T
M
P
E
M
N
G
I
D
A
I
K
E
--
I
M
K
I
D
P
N
A
K
I
I
V
C
S
A
M
G
Q
Q
A
M
V
I
E
A
I
K
A
G
A
K
D
F
I
V
K
P
F
Q
P
S
R
V
V
E
A
L
N
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
PsiBlast_CBE
50.80
32%
-128
- C1 -
-
1NXW
1
?
A:
[2-113]
-
K
K
I
L
I
V
D
D
E
K
P
I
S
D
I
I
K
F
N
M
T
K
E
G
-
Y
E
V
V
T
----
A
F
N
G
R
E
A
L
E
Q
F
E
A
E
Q
P
D
I
I
I
L
D
L
M
L
P
E
I
D
G
L
E
V
A
K
T
--
I
R
K
T
S
S
V
P
I
L
M
L
S
A
K
D
S
E
F
D
K
V
I
G
-
L
E
L
G
A
D
D
Y
V
T
K
P
F
S
N
R
E
L
Q
A
R
V
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
83
HHSearch
50.53
27%
-128
- C1 -
-
3OIO
-
?
A:
[5-111]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
Q
P
K
L
T
E
A
V
S
L
M
E
A
N
I
E
E
-
P
L
S
T
D
D
I
A
Y
Y
V
G
V
S
R
R
Q
L
E
R
L
F
K
Q
Y
L
G
T
V
P
S
K
Y
Y
L
E
L
R
L
N
R
A
R
Q
L
L
Q
Q
T
S
K
S
I
V
Q
I
G
L
A
C
G
F
S
S
G
P
H
F
S
S
T
Y
R
N
H
F
N
I
T
P
R
E
E
R
A
Q
R
A
Q
-----
34
PsiBlast_CBE
50.52
32%
-123
- C1 -
-
1NXP
1
?
A:
[2-113]
-
K
K
I
L
I
V
D
D
E
K
P
I
S
D
I
I
K
F
N
M
T
K
E
G
-
Y
E
V
V
T
----
A
F
N
G
R
E
A
L
E
Q
F
E
A
E
Q
P
D
I
I
I
L
D
L
M
L
P
E
I
D
G
L
E
V
A
K
T
--
I
R
K
T
S
S
V
P
I
L
M
L
S
A
K
D
S
E
F
D
K
V
I
G
-
L
E
L
G
A
D
D
Y
V
T
K
P
F
S
N
R
E
L
Q
A
R
V
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
81
HHSearch
50.44
35%
-130
- C1 -
-
3LSG
-
?
A:
[3-103]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
K
E
L
I
Q
N
I
I
E
E
S
Y
T
D
S
Q
F
T
L
S
V
L
S
E
K
L
D
L
S
S
G
Y
L
S
I
M
F
K
K
N
F
G
I
P
F
Q
D
Y
L
L
Q
K
R
M
E
K
A
K
L
L
L
L
T
T
E
L
K
N
Y
E
I
A
E
Q
V
G
F
E
D
V
N
Y
F
I
T
K
F
K
K
Y
Y
Q
I
T
P
K
Q
Y
R
E
---------
75
HHSearch
50.19
34%
-149
- C1 -
-
2K9S
-
A:
[3-106]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
R
V
R
E
A
C
Q
Y
I
S
D
H
L
A
D
S
N
F
D
I
A
S
V
A
Q
H
V
C
L
S
P
S
R
L
S
H
L
F
R
Q
Q
L
G
I
S
V
L
S
W
R
E
D
Q
R
I
S
Q
A
K
L
L
L
S
T
T
R
M
P
I
A
T
V
G
R
N
V
G
F
D
D
Q
L
Y
F
S
R
V
F
K
K
C
T
G
A
S
P
S
E
F
R
A
G
C
-------
3
PsiBlast_PDB
50.03
36%
-59
- C1 -
-
1S8N
-
PDTAR_MYCTU
A:
[15-130]
--
R
V
L
I
A
E
D
E
A
L
I
R
M
D
L
A
E
M
L
R
E
E
G
--
Y
E
I
--
V
G
E
A
G
D
G
Q
E
A
V
E
L
A
E
L
H
K
P
D
L
V
I
M
D
V
K
M
P
R
R
D
G
I
D
A
A
S
E
I
A
S
K
R
I
A
P
---
I
V
V
L
T
A
F
S
Q
R
D
L
V
E
R
A
R
D
A
G
A
M
A
Y
L
V
K
P
F
S
I
S
D
L
I
P
A
I
E
L
A
V
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
49.78
36%
-57
- C1 -
-
1SD5
-
PDTAR_MYCTU
A:
[15-130]
--
R
V
L
I
A
E
D
E
A
L
I
R
M
D
L
A
E
M
L
R
E
E
G
--
Y
E
I
--
V
G
E
A
G
D
G
Q
E
A
V
E
L
A
E
L
H
K
P
D
L
V
I
M
D
V
K
M
P
R
R
D
G
I
D
A
A
S
E
I
A
S
K
R
I
A
P
---
I
V
V
L
T
A
F
S
Q
R
D
L
V
E
R
A
R
D
A
G
A
M
A
Y
L
V
K
P
F
S
I
S
D
L
I
P
A
I
E
L
A
V
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
49.48
32%
-137
- C1 -
-
4QYW
-
CHEY_THEMA
A:
[4-117]
--
R
V
L
I
V
D
D
A
A
F
M
R
M
M
L
K
D
I
I
T
K
A
G
--
Y
E
V
A
--
G
E
A
T
N
G
R
E
A
V
E
K
Y
K
E
L
K
P
D
I
V
T
M
-
I
T
M
P
E
M
N
G
I
D
A
I
K
E
--
I
M
K
I
D
P
N
A
K
I
I
V
A
S
A
M
G
Q
Q
A
M
V
I
E
A
I
K
A
G
A
K
D
F
I
V
K
P
F
Q
P
S
R
V
V
E
A
L
N
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
49.41
30%
-131
- C1 -
-
5HEV
-
?
A:
[1-115]
M
I
K
V
L
L
V
D
D
H
E
M
V
R
L
G
V
S
S
Y
L
S
I
---
Q
E
D
I
E
V
I
G
E
A
E
N
G
R
Q
G
Y
E
K
A
M
A
L
R
P
D
V
I
L
M
D
L
V
M
E
E
M
D
G
I
E
S
T
K
A
--
I
L
K
D
W
P
K
A
K
I
I
I
V
T
S
F
I
D
D
E
K
V
Y
P
A
I
E
A
G
A
A
G
Y
L
L
K
T
S
T
A
H
E
I
A
D
A
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
84
HHSearch
49.22
32%
-132
- C1 -
-
3OOU
1
?
A:
[4-107]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
P
I
I
Q
N
V
L
S
Y
I
T
E
H
F
S
E
-
G
M
S
L
K
T
L
G
N
D
F
H
I
N
A
V
Y
L
G
Q
L
F
Q
K
E
M
G
E
H
F
T
D
Y
L
N
R
Y
R
V
N
Y
A
K
E
E
L
L
Q
T
K
D
N
L
T
I
I
A
G
K
S
G
Y
T
D
M
A
Y
F
Y
R
Q
F
K
K
H
T
G
E
T
P
N
R
Y
R
K
I
H
-------
93
HHSearch
49.00
25%
-143
* C1 *
-
3DZD
-
?
B:
[1-116]
-
K
R
V
L
V
V
D
D
E
E
S
I
T
S
S
L
S
A
I
L
E
E
E
----
G
Y
H
-
P
D
T
A
K
T
L
R
E
A
E
K
K
I
K
E
L
F
F
P
V
I
V
L
D
V
W
M
P
D
G
D
G
V
N
F
I
D
F
--
I
K
E
N
S
P
D
S
V
V
I
V
I
T
G
H
G
S
V
D
T
A
V
K
A
I
K
K
G
A
Y
E
F
L
E
K
P
F
S
V
E
R
F
L
L
T
I
K
H
A
F
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
PsiBlast_CBE
48.76
32%
-109
- C1 -
-
1YS7
1
PRRA_MYCTU
B:
[34-134]
--------------------------------
V
A
T
A
V
D
G
A
E
A
L
R
S
A
T
E
N
R
P
D
A
I
V
L
D
I
N
M
P
V
L
D
G
V
S
V
V
T
A
--
L
R
A
M
D
N
D
V
P
V
C
V
L
S
A
R
S
S
V
D
D
R
V
A
G
L
E
A
G
A
D
D
Y
L
V
K
P
F
V
L
A
E
L
V
A
R
V
K
----
A
L
L
R
R
R
G
S
T
A
T
S
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
48.63
35%
-145
- C1 -
-
2K9S
-
A:
[5-103]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
R
E
A
C
Q
Y
I
S
D
H
L
A
D
S
N
F
D
I
A
S
V
A
Q
H
V
C
L
S
P
S
R
L
S
H
L
F
R
Q
Q
L
G
I
S
V
L
S
W
R
E
D
Q
R
I
S
Q
A
K
L
L
L
S
T
T
R
M
P
I
A
T
V
G
R
N
V
G
F
D
D
Q
L
Y
F
S
R
V
F
K
K
C
T
G
A
S
P
S
E
F
R
----------