@TOME V2.3
(Mar 2018)
Ref.
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Q3Y2V1: (2018-02-02 )
MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMGMGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMTHDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYVVSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVADMIPAMIVIMPLSWMWTNWIMPLL
Atome Classification :
(20 SA)
-------------------------------------------------------........-------.10-----....--....---------20.....-..----.30........40...---.....--50...-.....60.......-.70-----------------.....-...80......---..-90........100.....---------..110----..-------------.......120.-----......130--....---...------140----.........150.......160---------...----------..------------------..-.170...----...--.180.........-----------190.....--..200.......-210---.......220....-------------------...230---.-.......-240-----------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
-------------------------------------------------------MP
T
G
V
L
I
N
-------
V
G
S
-----
V
L
F
G
--
G
L
I
G
---------
G
L
V
G
N
K
L
-
S
E
----
H
F
K
A
Q
L
T
M
V
F
G
V
C
S
MG---M
G
I
Y
S--IAPMK-N
M
P
A
V
I
F
A
L
V
I
G
T
A
-
I
G
L
-----------------
I
V
HLG-NGINKG
A
A
L
M
Q---V
P
-
I
S
KIFPSEKLGM
T
H
D
E
F
I
---------
S
T
L
------
V
T
-------------
V
I
V
L
F
CASGT
G
-----
I
Y
GSLDSGM--TGD
S
---
T
I
L
------
I
------
S
K
S
V
L
D
F
F
T
A
A
I
F
A
C
N
L
G
Y
V
V
----------
S
V
I
----------
A
I
------------------
P
Q
-
F
I
I
F
Y
I
L
----
F
L
L
--
A
K
--
F
IYPLT
T
P
D
-----------
M
I
L
D
FKAC--G
G
F
L
M
V
AT
G
F
R
M
-
I
N
V
---
K
MF
P
V
A
D
M
I
P
A
M
I
V
-------------------IMP
L
S
----
W
-
M
W
T
N
W
IM-PLL-----------------------
17
Fugue
67.98
18%
-82
- C7 -
-
5UDF
-
?
A:
[13-223]
----------------------------------------------------------------------------------------------------
D
R
E
L
-
K
N
----
R
V
L
G
M
V
P
Q
A
T
V
S
S
T
Q
I
---
L
T
D
W
P
E
L
V
K
R
V
E
-
N
H
P
H
V
T
G
V
A
P
F
T
Q
L
-
Q
G
M
-----------------
L
T
A
Q
G
--------
Q
V
A
G
---
I
M
-
V
T
G
I
D
P
K
Y
E
------
K
N
V
---------
S
I
I
------
Q
N
-------------
H
I
V
A
--------------
G
S
L
D
S
L
K
--
K
G
E
F
---
G
I
V
------
L
------
G
K
D
M
A
D
S
L
G
L
-----
R
L
N
D
S
V
----------
T
L
V
L
P
E
A
T
PSPAG
V
V
------------------
P
R
-
F
K
R
F
K
V
V
----
G
I
F
S
V
G
A
--
E
V
D
S
M
V
G
Y
I
-----------
A
L
Y
D
A
S
T
L
--
L
R
L
P
D
G
A
Q
G
V
R
L
-
K
L
D
---
D
I
F
A
A
P
Q
V
A
D
D
I
V
K
-------------------
N
L
P
S
N
----
F
-
Y
A
T
N
W
T
Y
-
T
N
L
FN---------------------
19
Fugue
65.53
20%
-65
- C5 -
-
4INO
-
?
A:
[34-335]
----------------------------------------Q
E
V
K
V
K
D
YF
G
E
Q
T
I
K
L
P
V
S
K
I
I
Y
-------
L
G
S
FAE
V
P
A
M
F
H
TW
D
R
V
V
---------
G
I
S
D
Y
A
F
K
S
D
----
I
V
K
A
T
L
K
D
P
E
R
I
K
P
M
S
SDH
A
A
A
L
N
--
V
E
L
L
K
-
K
L
S
P
D
L
V
V
T
F
V
G
N
P
-
K
A
V
E
H
A
K
K
F
GISFLSFQEKT
I
A
E
V
M
-
E
D
I
D
T
Q
A
K
A
L
E
---
V
D
-
A
S
K
K
L
--
A
K
M
Q
E
T
L
D
F
I
A
---------
E
R
L
KG
V
K
K
K
K
G
-------------
V
E
L
F
H
K
A
N
K
I
S
-----
G
H
Q
A
L
D
S
D
I
--
L
E
K
G
---
G
I
D
NFGLKY
V
------
K
F
G
R
A
D
I
S
V
E
K
I
V
K
E
N
P
E
I
I
F
I
W
WISPLS
P
E
D
V
L
----------
N
N
------------------
P
K
-
F
A
T
--
I
K
----
A
I
K
--
N
K
--
Q
V
Y
K
L
P
T
M
D
-----------
I
---------
G
G
P
R
A
P
L
I
S
L
F
I
-
A
L
K
A
HP
E
A
F
K
G
V
D
I
N
A
I
V
K
D
-------------------
Y
Y
K
V
V
----
F
D
L
N
D
A
E
V
E
-
P
F
L
WH---------------------
20
Fugue
63.31
17%
-49
- C6 -
-
3G8Q
-
CDAT8_METKA
A:
[1-278]
----------------------------------------------M
K
V
S
L
AGQT
V
D
V
K
K
I
L
N
E
IPKR
T
V
T
A
A
-----
L
L
E
G
--
G
E
I
V
---------
A
V
E
E
A
D
--
D
E
----
H
A
E
R
K
L
V
R
R
H
D
V
E
G
K
-----------
V
V
F
V
T
-
A
R
P
C
L
Y
C
A
R
E
L
A
E
A
G
V
A
G
-----------------
V
V
Y
L
G
-
R
G
R
G
L
G
P
Y
Y
L
A
R
S
G
V
E
-
V
V
E
V
H
P
D
E
P
L
G
Y
D
P
V
D
R
L
---------
D
V
L
------
L
T
F
G
GNPYLT
E
E
D
V
A
A
R
V
Y
C
L
L
T
G
R
G
-----
F
D
A
D
I
A
P
A
P
--
E
N
L
S
G
R
V
E
I
M
------
V
------
T
R
G
D
P
D
E
A
V
E
L
L
K
E
E
L
P
V
F
R
I
----------
R
R
F
----------
L
I
------------------
S
G
E
F
D
R
D
E
L
R
----
E
R
I
--
L
E
--
D
I
E
P
R
I
L
D
P
-----------
F
A
V
R
A
R
I
A
RA
G
A
F
----
S
S
S
R
E
-
A
E
V
---
F
I
G
D
V
L
T
S
V
G
R
E
V
N
-------------------
L
N
D
P
R
----
T
-
V
V
T
V
D
V
L
G
P
R
V
S
V
G
V
E
K
R----------------
23
Fugue
59.69
23%
-177
- C8 -
-
5KU5
-
CUSS_ECOLI
A:
[1-148]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
V
K
V
H
F
A
E
Q
D
I
N
D
L
K
E
I
S
---------
A
T
L
------
E
R
-------------
V
L
N
H
P
D
E
T
Q
A
R
-----
R
L
M
T
L
E
D
I
V
--
S
G
Y
S
---
N
V
L
------
I
------
S
--
L
A
D
S
Q
G
K
T
V
Y
H
S
P
---------------
G
A
P
----------
D
I
------------------
R
E
-
F
T
R
D
A
I
P
----
D
K
D
--
A
Q
G
G
E
V
Y
L
L
S
G
P
T
-----------
M
M
M
P
G
H
----
G
H
G
H
M
E
H
S
N
W
R
M
-
I
N
L
---
P
V
G
P
L
V
D
G
K
P
I
Y
T
L
-------------------
Y
I
A
L
S
I
D
F
H
L
-
H
Y
I
N
D
L
M
-
N
-------------------------
24
Fugue
59.42
14%
-21
- C3 -
-
3EDV
-
SPTB2_HUMAN
A:
[2-323]
S
H
M
R
H
R
L
F
Q
L
N
R
E
V
D
D
L
E
Q
W
I
A
E
R
E
V
V
A
G
SHELGQD
Y
E
H
V
T
M
L
Q
E
R
F
R
E
F
A
R
D
T
G
N
I
G
Q
E
R
V
D
-------
T
V
N
-----
H
L
A
D
--
E
L
I
N
S
GHSD
A
A
T
I
A
E
W
K
D
G
L
-
N
E
----
A
W
A
D
L
L
E
L
I
D
T
R
T
Q
I
L
---
A
A
S
Y
E
--
L
H
K
F
Y
-
H
D
A
K
E
I
F
G
R
I
Q
D
K
H
-
K
K
L
-----------------
P
E
E
L
G
-
R
D
---------------
Q
N
T
V
E
T
L
Q
R
M
H
T
T
F
E
H
D
I
---------
Q
A
L
------
G
T
-------------
Q
V
R
Q
L
Q
E
D
A
A
R
-----
L
Q
A
A
Y
-
A
G
D
--
K
A
D
D
---
I
Q
K
------
R
------
E
N
E
V
L
E
A
W
K
S
L
L
D
A
C
E
S
R
R
V
R
----------
L
V
D
----------
T
G
------------------
D
K
-
F
R
F
F
S
M
V
R
D
L
M
L
W
M
--
E
D
--
V
I
R
Q
I
E
A
Q
E
-----------
K
P
R
D
V
S
S
V
--
E
L
L
M
N
N
H
Q
G
I
K
A
E
I
D
A
---
R
N
D
S
F
T
T
C
I
E
L
G
K
S
-------------------
L
L
A
R
K
----
H
-
Y
A
S
E
E
I
K
-
E
K
L
L
Q
L
T
E
K
R
K
E
M
I
D
K
W
E
D
R
W
E
W
L
R
L
21
Fugue
44.35
10%
-82
- C4 -
-
1JMS
-
TDT_MOUSE
A:
[19-381]
---------KKISQYACQ
R
R
T
T
LNNYN
Q
L
F
T
D
A
L
D
I
L
A
E
N
D
E
L
R
EN
E
G
S
C
L
A
F
M
R
A
S
S
V
L
K
S
L
-------
P
F
P
-----
I
T
S
M
--
K
D
T
E
---------
G
I
P
C
--
L
-
G
D
----
K
V
K
S
I
I
E
G
I
I
E
D
G
E
S
S
---
E
A
K
A
V
--
L
N
D
E
R
-
Y
K
S
F
K
L
F
T
S
V
F
G
V
G
-
L
K
T
-----------------
A
E
K
W
F
R
M
G
F
R
T
L
S
K
I
Q
S
---
D
K
-
S
L
R
F
T
Q
M
Q
K
A
G
F
L
Y
Y
E
D
L
VSCVN
R
P
E
A
E
A
V
------
S
M
-------------
L
V
K
E
A
V
V
T
F
L
P
D
A
L
V
T
M
T
G
G
F
R
R
G
K
MT
G
H
D
V
---
D
F
L
------
I
T
S
PEAT
E
D
E
E
Q
Q
L
L
H
K
V
T
D
F
W
K
Q
Q
G
L
L
----------
L
Y
C
----------
D
I
L
E
S
TFEKFKQPSRKVDAL
D
H
-
F
Q
K
C
F
L
I
----
L
K
L
--
D
H
--
G
R
V
H
S
E
K
S
E
GKG
W
K
A
I
R
V
D
L
V
M
C
P
Y
D
R
R
--
A
F
A
L
L
G
W
T
G
S
R
Q
-
F
E
R
---
D
L
R
R
Y
A
T
H
E
R
K
M
M
L
D
NH
A
L
Y
D
RTKR
V
F
L
E
A
ES
E
E
E
I
F
A
----
H
-
L
G
L
D
Y
I
E
-
P
W
E
RNA--------------------
5
PsiBlast_PDB
40.35
39%
-110
- C9 -
-
1BSM
-
SODM_PROFR
A:
[92-124]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
T
D
E
L
G
A
A
I
D
E
F
F
---------
G
S
F
------
D
N
-------------
M
K
A
Q
F
T
A
A
A
T
G
-----
I
Q
G
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
39.20
39%
-113
- C9 -
-
1AVM
-
SODM_PROFR
A:
[92-124]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
T
D
E
L
G
A
A
I
D
E
F
F
---------
G
S
F
------
D
N
-------------
M
K
A
Q
F
T
A
A
A
T
G
-----
I
Q
G
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
39.03
39%
-109
- C9 -
-
1AR4
-
SODM_PROFR
A:
[92-124]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
T
D
E
L
G
A
A
I
D
E
F
F
---------
G
S
F
------
D
N
-------------
M
K
A
Q
F
T
A
A
A
T
G
-----
I
Q
G
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
37.98
39%
-110
- C9 -
-
1AR5
-
SODM_PROFR
A:
[92-124]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
T
D
E
L
G
A
A
I
D
E
F
F
---------
G
S
F
------
D
N
-------------
M
K
A
Q
F
T
A
A
A
T
G
-----
I
Q
G
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
37.96
39%
-92
- C9 -
-
1BT8
-
SODM_PROFR
A:
[92-124]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
T
D
E
L
G
A
A
I
D
E
F
F
---------
G
S
F
------
D
N
-------------
M
K
A
Q
F
T
A
A
A
T
G
-----
I
Q
G
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
36.43
39%
-91
- C9 -
-
1BS3
-
SODM_PROFR
A:
[92-124]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
T
D
E
L
G
A
A
I
D
E
F
F
---------
G
S
F
------
D
N
-------------
M
K
A
Q
F
T
A
A
A
T
G
-----
I
Q
G
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
HHSearch
34.67
11%
-205
- C9 -
-
5UNI
6
?
B:
[60-126]
-----------------------------------------------------------------------
L
A
-----
L
L
L
G
--
S
V
V
A
---------
W
W
A
A
V
R
V
-
A
M
TD
M
P
Q
M
V
A
I
Y
N
G
M
G
G
G
A
A
A
T
---
I
A
A
V
E
--
L
L
K
G
A
F
E
N
T
G
L
M
A
L
A
I
L
G
G
L
-
I
G
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
33.29
15%
-139
- C9 -
-
5SV0
-
EXBB_ECOLI
A:
[149-194]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
W
G
I
M
N
-----
S
F
I
G
I
A
Q
T
Q
--
T
T
N
L
---
A
-----------------
V
V
A
P
G
I
A
E
A
L
L
A
T
A
I
G
L
V
A
----------
A
I
P
----------
A
V
------------------
V
I
----------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
33.23
14%
-76
- C9 -
-
4XYP
1
?
A:
[45-58]
-----------------------------------------------------------------------------------------------------------------------------------------------------------
G
L
-
I
G
E
-----------------
Y
L
N
I
S
-
S
W
L
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
32.19
15%
-100
- C9 -
-
5SV0
-
EXBB_ECOLI
C:
[149-194]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
W
G
I
M
N
-----
S
F
I
G
I
A
Q
T
Q
--
T
T
N
L
---
A
-----------------
V
V
A
P
G
I
A
E
A
L
L
A
T
A
I
G
L
V
A
----------
A
I
P
----------
A
V
------------------
V
I
----------------------------------------------------------------------------------------------------------------------------------------------------
22
Fugue
31.55
17%
-114
* C9 *
-
1G2Y
-
HNF1A_MOUSE
B:
[1-30]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
V
S
K
L
S
Q
L
Q
---
T
E
M
L
A
A
L
L
E
S
---
G
L
S
K
E
A
L
I
---------
Q
A
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
Fugue
30.47
17%
-54
- C9 -
-
1G2Y
-
HNF1A_MOUSE
C:
[2-30]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
S
K
L
S
Q
L
Q
---
T
E
M
L
A
A
L
L
E
S
---
G
L
S
K
E
A
L
I
---------
Q
A
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
Fugue
27.23
17%
-44
- C9 -
-
1G2Y
-
HNF1A_MOUSE
D:
[1-30]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
V
S
K
L
S
Q
L
Q
---
T
E
M
L
A
A
L
L
E
S
---
G
L
S
K
E
A
L
I
---------
Q
A
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
27.13
26%
7
- C9 -
-
5A43
-
?
B:
[2-28]
------------------------------------------------------------
I
K
S
-------
L
F
A
-----
V
I
I
G
--
G
S
V
G
---------
C
T
L
R
W
L
L
-
S
T
----
K
F
N
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------