@TOME V2.3
(Mar 2018)

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Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
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Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : HDA10_HUMAN: (2017-06-15 )
MGTALVYHEDMTATRLLWDDPECEIERPERLTAALDRLRQRGLEQRCLRLSAREASEEELGLVHSPEYVSLVRETQVLGKEELQALSGQFDAIYFHPSTFHCARLAAGAGLQLVDAVLTGAVQNGLALVRPPGHHGQRAAANGFCVFNNVAIAAAHAKQKHGLHRILVVDWDVHHGQGIQYLFEDDPSVLYFSWHRYEHGRFWPFLRESDADAVGRGQGLGFTVNLPWNQVGMGNADYVAAFLHLLLPLAFEFDPELVLVSAGFDSAIGDPEGQMQATPECFAHLTQLLQVLAGGRVCAVLEGGYHLESLAESVCMTVQTLLGDPAPPLSGPMAPCQSALESIQSARAAQAPHWKSLQQQDVTAVPMSPSSHSPEGRPPPLLPGGPVCKAAASAPSSLLDQPCLCPAPSVRTAVALTTPDITLVLPPDVIQQEASALREETEAWARPHESLAREEALTALGKLLYLLDGMLDGQVNSGIAATPASAAAATLDVAVRRGLSHGAQRLLCVALGQLDRPPDLAHDGRSLWLNIRGKEAAALSMFHVSTPLPVMTGGFLSCILGLVLPLAYGFQPDLVLVALGPGHGLQGPHAALLAAMLRGLAGGRVLALLEENSTPQLAGILARVLNGEAPPSLGPSSVASPEDVQALMYLRGQLEPQWKMLQCHPHLVA

Atome Classification :

(54 SA) -------.........10........--20-.........30........40........50........60........70-----..-......80...--.------...--------------.90-----------.........100.......110.......120.......130.......140.......150.......--160-...-.....170.......180.......190.......200.......210.......220.......---230.......240.......250.......260.......270--.......280.......290.----.----.....300.......310.......320.---......330--........340.......350......------.360.......370.......380--------------.......390.......400.......410.......420..---.....430.......440.......450----........460.......470.......480------.......------..490.......500.......------510.......520.......530---------.......540-------.......---.550.......560.......570.......580-----......--...590.......600.......610--.........620.......630.......640.......650.......660.......----
(Atome) (Ident) (Tito) (Num) (QMean) (Ligand) (Uniprot) -------MGTALVYHEDMTATRLLWD--D--PECEIERPERLTAALDRLRQRGLEQRCLRLSAREASEEELGLVHSPEYVSL-----VR-ETQVLGKEELQ--A------LSG--------------QF------------DAIYFHPSTFHCARLAAGAGLQLVDAVLTGAVQNGLALVRPPGHHGQRAAANGFCVFNNVAIAAAHAKQ--K-H-GLH-RILVVDWDVHHGQGIQYLFEDDPSVLYFSWHRYEHGRFWPFLRESDADAVGRGQGLGFTVNLPWN---QVGMGNADYVAAFLHLLLPLAFEFDPELVLVSAGFDSAIGDPE--GQMQATPECFAHLTQLLQVLA----G----GRVCAVLEGGYHLESLAESVCMTVQTLLG---DPAPPLSG---PMAPCQSALESIQSARAAQAPHWKSLQ------QQDVTAVPMSPSSHSPEGRPPPLL--------------PGGPVCKAAASAPSSLLDQPCLCPAPSVRTAVALTTPDITLV---LPPDVIQQEASALREETEAWARPHESL-----AREEALTALGKLLYLLDGMLDGQVNSGIA--------ATPASAA------AATLDVAVRRGLSHGAQRLLCV------ALGQLDRPPDLAHDGRSLWLNIR---------GKEAAALSM--------FHVSTPL---PVMTGGFLSCILGLVLPLAYGFQPDLVLVALG-------PGHGLQ--GPHAALLAAMLRGLAGGRVLALLE----ENSTPQLAGILARVLNGEAPPSLGPSSVASPEDVQALMYLRGQLEPQWKMLQCHPHLVA----
89 HHSearch 85.6954%-122 - C3 - - 5G0G ? A:[24-379] --------GTGLVYVDAFTRFHCLWD------ASHPECPARVSTVMEMLETEGLLGRCVQVEARAVTEDELLLVHTKEYVEL-----MK-STQNMTEEELK--T------LAE--------------KY------------DSVYLHPGFFSSACLSVGSVLQLVDKVMTSQLRNGFSINRPPGHHAQADKMNGFCMFNNLAIAARYAQK--R-H-RVQ-RVLIVDWDVHHGQGIQYIFEEDPSVLYFSVHRYEDGSFWPHLKESDSSSVGSGAGQGYNINLPWN---KVGMESGDYITAFQQLLLPVAYEFQPQLVLVAAGFDAVIGDPK--GGMQVSPECFSILTHMLKGVA----Q----GRLVLALEGGYNLQSTAEGVCASMRSLLG---DPCPHLPS---SGAPCESALKSISKTISDLYPFWKSLQ------T-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21 PsiBlast_CBE 78.6253% 0 - C- - - 5G0I ? B:[40-417] --------GTGLVYVDAFTRFHCLWDASH--PEC----PARVSTVMEMLETEGLLGRCVQVEARAVTEDELLLVHTKEYVEL-----MK-STQNMTEEELK--T------LAE--------------KY------------DSVYLHPGFFSSACLSVGSVLQLVDKVMTSQLRNGFSINRPPGHHAQADKMNGFCMFNNLAIAARYAQK--R-H-RVQ-RVLIVDWDVHHGQGIQYIFEEDPSVLYFSVHRYEDGSFWPHLKESDSSSVGSGAGQGYNINLPWN---KVGMESGDYITAFQQLLLPVAYEFQPQLVLVAAGFDAVIGDPK--GGMQVSPECFSILTHMLKGVA----Q----GRLVLALEGGYNLQSTAEGVCASMRSLLG---DPCPHLPS---SGAPCESALKSISKTISDLYPFWKSLQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1 PsiBlast_PDB 78.6253% 0 - C- - - 5G0I ? A:[40-416] --------GTGLVYVDAFTRFHCLWDASH--PEC----PARVSTVMEMLETEGLLGRCVQVEARAVTEDELLLVHTKEYVEL-----MK-STQNMTEEELK--T------LAE--------------KY------------DSVYLHPGFFSSACLSVGSVLQLVDKVMTSQLRNGFSINRPPGHHAQADKMNGFCMFNNLAIAARYAQK--R-H-RVQ-RVLIVDWDVHHGQGIQYIFEEDPSVLYFSVHRYEDGSFWPHLKESDSSSVGSGAGQGYNINLPWN---KVGMESGDYITAFQQLLLPVAYEFQPQLVLVAAGFDAVIGDPK--GGMQVSPECFSILTHMLKGVA----Q----GRLVLALEGGYNLQSTAEGVCASMRSLLG---DPCPHLPS---SGAPCESALKSISKTISDLYPFWKSLQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23 PsiBlast_CBE 76.2952% -80 - C3 - - 5EDU HDAC6_HUMAN (first) A:[391-745] ---------TGLVYDQNMMNHCNLWD--S--HHPEV--PQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEYVGH-----LR-ATEKMKTRELH--R------ESS--------------NF------------DSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQT--I-S-GHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWN---GPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPL--GGCQVSPEGYAHLTHLLMGLA----S----GRIILILEGGYNLTSISESMAACTRSLLG---DPPPLLTL---PRPPLSGALASITETIQVHRRYWRSLR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
92 HHSearch 75.5052% -74 - C3 - - 5EDU HDAC6_HUMAN (first) B:[389-745] -------SRTGLVYDQNMMNHCNLWD------SHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEYVGH-----LR-ATEKMKTRELH--R------ESS--------------NF------------DSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQT--I-SGHAL-RILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWN---GPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPL--GGCQVSPEGYAHLTHLLMGLA----S----GRIILILEGGYNLTSISESMAACTRSLLG---DPPPLLT-----RPPLSGALASITETIQVHRRYWRSLR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
110 Fugue 75.0239% -6 - C3 - - 5G0J ? A:[17-772] VQGKSKATGTGLVYVDAFTRFHCLWD--ASHPEC----PARVSTVMEMLETEGLLGRCVQVEARAVTEDELLLVHTKEYVEL-----MK-STQNMTEEELK--T------LAE--------------KY------------DSVYLHPGFFSSACLSVGSVLQLVDKVMTSQLRNGFSINRPPGHHAQADKMNGFCMFNNLAIAARYAQK--R-H-RVQ-RVLIVDWDVHHGQGIQYIFEEDPSVLYFSVHRYEDGSFWPHLKESDSSSVGSGAGQGYNINLPWN---KVGMESGDYITAFQQLLLPVAYEFQPQLVLVAAGFDAVIGDPK--GGMQVSPECFSILTHMLKGVA----Q----GRLVLALEGGYNLQSTAEGVCASMRSLLG---DPCPHLPS---SGAPCESALKSISKTISDLYPFWKSLQTFEGGPLSEVSPLPAPVCAEVKVSSPITGLVYDQRMMLHHNMWDSHHPELPQRISRIFSRHEELRLLSRCHRIPARLATEEELALCHSSKHISIIKSSEHMKPRDLNRLGDEYNSIFISNESYTCALLAAGSCFNSAQAILTGQVRNAVAIVRPPGHHAEKDTACGFCFFNTAALTARYAQSITRESLRVLIVDWDVHHGNGTQHIFEE---DDSVLYISLHRYEDGAFFPNSEDANYDKVGLGKGRGYNVNIPWNGGKMGDPEYMAAFHHLVMPIAREFAPELVLVSAGFDAARGDPLGGFQVTPEGYAHLTHQLMSLAAGRVLIILEGGYNLTSISESMSMCTSMLLGDSPPSLDHLTPLKTSATVSINNVLRAHAPFWSSLRVNIPESLRLSL
5 PsiBlast_PDB 74.7852% -75 - C3 - - 5EDU HDAC6_HUMAN (first) B:[391-745] ---------TGLVYDQNMMNHCNLWD--S--HHPEV--PQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEYVGH-----LR-ATEKMKTRELH--R------ESS--------------NF------------DSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQT--I-S-GHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWN---GPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPL--GGCQVSPEGYAHLTHLLMGLA----S----GRIILILEGGYNLTSISESMAACTRSLLG---DPPPLLT-----RPPLSGALASITETIQVHRRYWRSLR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
90 HHSearch 73.6345% -69 - C3 - - 5G0H ? A:[406-763] --------ITGLVYDQRMMLHHNMWD------SHHPELPQRISRIFSRHEELRLLSRCHRIPARLATEEELALCHSSKHISI-----IK-SSEHMKPRDLN--R------LGD--------------EY------------NSIFISNESYTCALLAAGSCFNSAQAILTGQVRNAVAIVRPPGHHAEKDTACGFCFFNTAALTARYAQS--ITR-ESL-RVLIVDWDVHHGNGTQHIFEEDDSVLYISLHRYEDGAFFPNSEDANYDKVGLGKGRGYNVNIPWN---GGKMGDPEYMAAFHHLVMPIAREFAPELVLVSAGFDAARGDPL--GGFQVTPEGYAHLTHQLMSLA----A----GRVLIILEGGYNLTSISESMSMCTSMLLG---DSPPSLDH---LTPLKTSATVSINNVLRAHAPFWSSLR------VN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
87 HHSearch 73.1146% -69 - C3 - - 5EEI ? A:[8-364] -------PITGLVYDQRMMLHHNMWD------SHHPELPQRISRIFSRHEELRLLSRCHRIPARLATEEELALCHSSKHISI-----IK-SSEHMKPRDLN--R------LGD--------------EY------------NSIFISNESYTCALLAAGSCFNSAQAILTGQVRNAVAIVRPPGHHAEKDTACGFCFFNTAALTARYAQS--ITR-ESL-RVLIVDWDVHHGNGTQHIFEEDDSVLYISLHRYEDGAFFPNSEDANYDKVGLGKGRGYNVNIPWN---GGKMGDPEYMAAFHHLVMPIAREFAPELVLVSAGFDAARGDPL--GGFQVTPEGYAHLTHQLMSLA----A----GRVLIILEGGYNLTSISESMSMCTSMLLG---DSPPSLDH---LTPLKTSATVSINNVLRAHAPFWSSLR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29 PsiBlast_CBE 72.6446% -64 - C3 - - 5EEM ? A:[10-363] ---------TGLVYDQRMMLHHNMWD--S--HHPEL--PQRISRIFSRHEELRLLSRCHRIPARLATEEELALCHSSKHISI-----IK-SSEHMKPRDLN--R------LGD--------------EY------------NSIFISNESYTCALLAAGSCFNSAQAILTGQVRNAVAIVRPPGHHAEKDTACGFCFFNTAALTARYAQSITR-E-SL--RVLIVDWDVHHGNGTQHIFEEDDSVLYISLHRYEDGAFFPNSEDANYDKVGLGKGRGYNVNIPWN---GGKMGDPEYMAAFHHLVMPIAREFAPELVLVSAGFDAARGDPL--GGFQVTPEGYAHLTHQLMSLA----A----GRVLIILEGGYNLTSISESMSMCTSMLLG---DSPPSLD-----TPLKTSATVSINNVLRAHAPFWSSL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26 PsiBlast_CBE 72.2846% -63 - C3 - - 5EF8 ? B:[10-364] ---------TGLVYDQRMMLHHNMWD--S--HHPEL--PQRISRIFSRHEELRLLSRCHRIPARLATEEELALCHSSKHISI-----IK-SSEHMKPRDLN--R------LGD--------------EY------------NSIFISNESYTCALLAAGSCFNSAQAILTGQVRNAVAIVRPPGHHAEKDTACGFCFFNTAALTARYAQSITR-E-SL--RVLIVDWDVHHGNGTQHIFEEDDSVLYISLHRYEDGAFFPNSEDANYDKVGLGKGRGYNVNIPWN---GGKMGDPEYMAAFHHLVMPIAREFAPELVLVSAGFDAARGDPL--GGFQVTPEGYAHLTHQLMSLA----A----GRVLIILEGGYNLTSISESMSMCTSMLLG---DSPPSLDH---LTPLKTSATVSINNVLRAHAPFWSSLR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28 PsiBlast_CBE 72.0346% -61 - C3 - - 5EEN ? A:[10-364] ---------TGLVYDQRMMLHHNMWD--S--HHPEL--PQRISRIFSRHEELRLLSRCHRIPARLATEEELALCHSSKHISI-----IK-SSEHMKPRDLN--R------LGD--------------EY------------NSIFISNESYTCALLAAGSCFNSAQAILTGQVRNAVAIVRPPGHHAEKDTA