@TOME V2.3
(Mar 2018)

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Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : HDAC8_HUMAN: (2017-06-15 )
MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVV

Atome Classification :

(102 SA) .........10........20.......--.30........40........50........60........70........80........-90....-....-100.......110.......120.......130.......140.......150.......160.....--.-.170.......180.......190.......200....-...-210.......220.......230....----...240.......250.......260.......270.......280.----......290.......300.------......310.......320.......330.......340.......350.......360.......370.....
(Atome) (Ident) (Tito) (Num) (QMean) (Ligand) (Uniprot) MEEPEEPADSGQSLVPVYIYSPEYVSMC--DSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDD-HPDSIE-YGLG-YDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRR--K-FERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPG-FFP-GTGDVSDVGLGKGRYYSVNVPIQDGIQ----DEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVG----IGKCLKYILQWQLATLILGG------GGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVV
138 HHSearch 92.0299%-130 - C3 - - 5DC8 HDAC8_HUMAN A:[14-376] -------------LVPVYIYSPEYVSMC--DSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDD-HPDSIE-YGLG-YDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWAHAKKDEASGFCYLNDAVLGILRLRR--K-FERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPG-FFP-GTGDVSDVGLGKGRYYSVNVPIQDGIQ----DEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVG----IGKCLKYILQWQLATLILGG------GGFNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHV-
78 PsiBlast_CBE 92.0299%-130 - C3 - - 5DC8 HDAC8_HUMAN A:[14-376] -------------LVPVYIYSPEYVSMC--DSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDD-HPDSIE-YGLG-YDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWAHAKKDEASGFCYLNDAVLGILRLRR--K-FERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPG-FFP-GTGDVSDVGLGKGRYYSVNVPIQDGIQ----DEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVG----IGKCLKYILQWQLATLILGG------GGFNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHV-
35 PsiBlast_CBE 91.9799%-130 - C3 - - 4QA1 HDAC8_HUMAN D:[14-377] -------------LVPVYIYSPEYVSMC--DSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDD-HPDSIE-YGLG-YDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRR--K-FERILYVDLDLHHGDGVEDTFSFTSKVMTVSLHKFSPG-FFP-GTGDVSDVGLGKGRYYSVNVPIQDGIQ----DEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVG----IGKCLKYILQWQLATLILGG------GGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVV
77 PsiBlast_CBE 91.9499%-134 - C3 - - 5DC8 HDAC8_HUMAN B:[14-376] -------------LVPVYIYSPEYVSMC--DSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDD-HPDSIE-YGLG-YDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWAHAKKDEASGFCYLNDAVLGILRLRR--K-FERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPG-FFP-GTGDVSDVGLGKGRYYSVNVPIQDGIQ----DEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVG----IGKCLKYILQWQLATLILGG------GGFNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHV-
60 PsiBlast_CBE 91.8999%-132 - C3 - - 4QA5 HDAC8_HUMAN B:[13-377] ------------SLVPVYIYSPEYVSMC--DSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDD-HPDSIE-YGLG-YDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRR--K-FERILYVDLDLHHGDGVEDTFSFTSKVMTVSLHKFSPG-FFP-GTGDVSDVGLGKGRYYSVNVPIQDGIQ----DEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVG----IGKCLKYILQWQLATLILGG------GGFNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVV
50 PsiBlast_CBE 91.7499%-131 - C3 - - 4QA4 HDAC8_HUMAN A:[13-377] ------------SLVPVYIYSPEYVSMC--DSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDD-HPDSIE-YGLG-YDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRR--K-FERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPG-FFP-GTGDVSDVGLGKGRYYSVNVPIQDGIQ----DEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVG----IGKCLKYILQWQLATLILGG------GGYNLANTARCWTYLTGVILGKTLSSEIPDREFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVV
72 PsiBlast_CBE 91.6799%-131 - C3 - - 5DC7 HDAC8_HUMAN A:[13-376] ------------SLVPVYIYSPEYVSMC--DSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDD-HPDSIE-YGLG-YDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRR--K-FERILYVALDLHHGDGVEDAFSFTSKVMTVSLHKFSPG-FFP-GTGDVSDVGLGKGRYYSVNVPIQDGIQ----DEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVG----IGKCLKYILQWQLATLILGG------GGFNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHV-
37 PsiBlast_CBE 91.6199%-130 - C3 - - 4QA1 HDAC8_HUMAN B:[14-377] -------------LVPVYIYSPEYVSMC--DSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDD-HPDSIE-YGLG-YDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRR--K-FERILYVDLDLHHGDGVEDTFSFTSKVMTVSLHKFSPG-FFP-GTGDVSDVGLGKGRYYSVNVPIQDGIQ----DEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVG----IGKCLKYILQWQLATLILGG------GGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVV
59 PsiBlast_CBE 91.4899%-130 - C3 - - 3EWF HDAC8_HUMAN A:[14-377] -------------LVPVYIYSPEYVSMC--DSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDD-HPDSIE-YGLG-YDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHAAKKDEASGFCYLNDAVLGILRLRR--K-FERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPG-FFP-GTGDVSDVGLGKGRYYSVNVPIQDGIQ----DEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVG----IGKCLKYILQWQLATLILGG------GGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVV
46 PsiBlast_CBE 91.4699%-134 - C3 - - 5DC6 HDAC8_HUMAN B:[14-377] -------------LVPVYIYSPEYVSMC--DSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDD-HPDSIE-YGLG-YDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRR--K-FERILYVNLDLHHGDGVEDAFSFTSKVMTVSLHKFSPG-FFP-GTGDVSDVGLGKGRYYSVNVPIQDGIQ----DEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVG----IGKCLKYILQWQLATLILGG------GGFNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVV
67 PsiBlast_CBE 91.4399%-132 - C3 - - 4QA0 HDAC8_HUMAN A:[14-377] -------------LVPVYIYSPEYVSMC--DSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDD-HPDSIE-YGLG-YDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFFYLNDAVLGILRLRR--K-FERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPG-FFP-GTGDVSDVGLGKGRYYSVNVPIQDGIQ----DEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVG----IGKCLKYILQWQLATLILGG------GGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVV
76 PsiBlast_CBE 91.3999%-134 - C3 - - 5D1D HDAC8_HUMAN A:[14-377] -------------LVPVYIYSPEYVSMC--DSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDD-HLDSIE-YGLG-YDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRR--K-FERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPG-FFP-GTGDVSDVGLGKGRYYSVNVPIQDGIQ----DEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVG----IGKCLKYILQWQLATLILGG------GGFNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVV
74 PsiBlast_CBE 91.2499%-133 - C3 - - 5D1C HDAC8_HUMAN A:[14-377] -------------LVPVYIYSPEYVSMC--DSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDD-HPDSIE-YGLG-YDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRR--K-FERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPG-FFP-GTGDVSDVGLGKGRYYSVNVPIQGGIQ----DEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVG----IGKCLKYILQWQLATLILGG------GGFNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVV
47 PsiBlast_CBE 91.1799%-133 - C3 - - 5DC6 HDAC8_HUMAN A:[14-376] -------------LVPVYIYSPEYVSMC--DSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDD-HPDSIE-YGLG-YDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRR--K-FERILYVNLDLHHGDGVEDAFSFTSKVMTVSLHKFSPG-FFP-GTGDVSDVGLGKGRYYSVNVPIQDGIQ----DEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVG----IGKCLKYILQWQLATLILGG------GGFNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHV-
44 PsiBlast_CBE 91.1699%-131 - C3 - - 4QA3 HDAC8_HUMAN B:[14-377] -------------LVPVYIYSPEYVSMC--DSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEG--D-HPDSIE-YGLG-YDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRR--K-FERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPG-FFP-GTGDVSDVGLGKGRYYSVNVPIQDGIQ----DEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVG----IGKCLKYILQWQLATLILGG------GGYNLANMARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVV
34 PsiBlast_CBE 91.1599%-128 - C3 - - 2V5W HDAC8_HUMAN B:[10-376] ---------SGQSLVPVYIYSPEYVSMC--DSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDD-HPDSIE-YGLG-YDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRR--K-FERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPG-FFP-GTGDVSDVGLGKGRYYSVNVPIQDGIQ----DEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVG----IGKCLKYILQWQLATLILGG------GGFNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHV-