Atome 2 Filter

Query sequence : LinJ_08_0540: (2018-03-08 )
MRAAAHHHHLPPLLCASTFHITRIRSPAAQHTPIRNAVRRGTRTNSTAAAVNVSAYSFAAPPLTNPYAYAASPSPSSAPSMRTVGVAAAAAAMSTVHAASVTNSGAAAHTWTNGGRGGHGAAHALTNSGRDVSLVLLTVACTLLVVTIVLLIVGVRLLKRFAAAVAAAEGARGQDILSNNLSAGEAAAYISVGIVDDDDEAALHTDNGDSRTQLVEYADEREPLLHHVRGRGGGAGRHRRSASRQHQQPGRRTTLAVFEALSILLGVSSTPPTADASSHGAAAAPRRRSRSCQAGSSAVPTPENQPALRSSPQQQRHAGRRAVPDALAADENSRGAFRSGPQPTWHSNGSLSRSGAARKCDEAAVAPASASPAPASHPAAAPGSSAAPATADHGATPPSGNSQLPVFTTTTEKDMVVYNTTHNSRYRLLQRIGIGAFSSVYLVQHKTTGKQYALKYILCKGDRERLAALRECEVIYSLQGHPQVIRIVDMFMSYQFQRASPSPTVAGSPTAAATNSACKEQASGQQGLRSFPGVPPSAPAAPAAALAPSAIATPALAPASAAPASTYTTSVAGRLKGLNDAALTKAAMESSTESRAAAHSEADDGHVDFSCVDRDRYSEGRWRGSRPRVRPSVEGVACGACMVNVDHASDVENGESAYSEHQQPQQPGKLSMRASSVCCPRPLPHSVQHTSQSSSSVHPTLSAAASASTAPATASSSSALAGSSYVPAQLCAAAGGGAQGCGHVPSQSAHHSSTTASAARAAATGSLSPPRDEAHADQPHLCCHAIDVPDAVVHDESDATAPVNASARCCAAHSTTTTAASMHPCFPSTTRNATVSRSSEASHEPGTLEDYDGGDGVHSGSDSRRRAEQGQSATGERAKPALQSRRASSEGRGSDGADDGHADIEAGREERRTELCGDADADEMHSCKGSDARSGATSSSGADEEPIQPIHRIFVPPPYMHPPLNGMASAPRSCSICSNNSVSYAGTGNGAASVLRPQSRTCATGGESPTSHHLYSAFPTAAAGGALAVVGPETANGSTAPAPVRRIAERPDVGSLSETASPPPFAAASASLTSSSPSPSAAVNLRHTAGSLVSTSTLPHQQQQQHPQPIPSSVTSYAPARAAVSSADVKSAATGAPAVQAPIRYKDFVLSPTTVTAHAAASWTPVPATQANALVDGQTHRQPADRGGSPAPPPCAASARVGSGAAGAGATGLTVARPTDECVNPYLERARGREPVPPPRTSYAPGGGVRYNSLTVPYVAAPTTLQAAAKGFPAQSSSPSSSLTLSASGTGVSAFDERKAGAGQGRRFEVTGADSSSQDSDASMPASQAARLTASRSLPSTAPAAATVVRNTYAPLRYGNVVQSNAASPATSSMASSSLMPPPSPSLQKQLPQPPSAACPAAAAPTVGSGRLSVCGVLRTARAGQQGEREDWDDGKPRVSASWPAKDAGLVSTQAPPLLPLPGLANQTSGAYFLRSVGRVNGAGAVPRAATPRAPYGEGRPPAAAAAQDEAPSPTRPLYTNLGVLIAGPSMTADPATATTTHVLRTGVQPPSPRHPRSNSYAGDDADRKRQRGYSNVGLTGAAPSEVRYTNAGSPNLWNAYNAGASPASAASAAAVAALTGLSPRIGAKTPTAACAGESNINDGKSSKTTHTNSSSSHLQDVCDTGYLCLVMEHHPMGDLCRYALRAQHELEMRRHRQKQSQSQALARSSLMSVGILQPITSPATATTQSRTCTSERSSAQQPQAPTKNATERDGGGTGAEAGESTSPLSLRPLSLTHGGAAGSAAAALSLLAAAADATWTVKVAMSRTDLHPALSAGVGGRGNTSGSHTAGGTDGDERATDFDTQRAASVAVDPTSENPLTEAQLLSIAYQLASVLDHMHQQNPPIVHRDLKPENILIKGELIDYLDLPLSAVLASTNNTVHCGGKDDALGKSSVSPMTPPFTTPAAVIDAAASSLTSLPPIRITRAVVPIVLIDFGLAILQDTHGRSHGSRGGGTRPYIAPESWKGDTCTASDVWSLGCVLYALATCRLVAEDVRIMSQEAKRDGFASRMLKDIIAHKYSLAFASFVVSLLVVDPAKRPTAAQAARCFCVADGDICFDLSSPFFSNVLDL

Atome Classification :

	(20 SA)										.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350........360.......370..-.....380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......---550.......560.......570.......580.......590.......600.......610.......620.......630........640.......650.......660....-...670.......680.......690.......700.......710.......720.......730.......740.......750.......760.......770.......780.......790.......800.......810.......820.......830.......840.......850.......860.......870.......880.......890.......900.......910.......920.......930.......940.......950.......960.......970.......980.......990.......1000......1010......1020......1030......1040......1050......1060......1070......1080......1090......1100......1110......1120......1130......1140......1150......1160......1170......1180......1190......1200......1210......1220......1230......1240......1250......1260......1270......1280......1290......1300......1310......1320......1330......1340......1350......1360......1370......1380......1390......1400......1410......1420......1430......1440......1450......1460......1470......1480......1490......1500......1510......1520......1530......1540......1550......1560......1570......1580......1590......1600......1610......1620......1630......1640......1650......1660......1670......1680......1690......1700......1710......1720......1730......1740......1750......1760......1770......1780......1790......1800.----.....1810......1820......1830......1840......----1850.-.....1860......1870......1880......1890-......1900......1910......1920......1930......1940......1950......1960-----........1970-.........1980......----1990......2000.....----.--2010-.-.......2020......2030........--2040--.--..-.------.----...-----------------------2050-------------------------------------.---------.--..--....2060......2070......2080......2090..-..----------..2100......2110-------------------------------------------------
		(Atome)	(Ident)	(Tito)	(Num)	(QMean)		(Ligand)	(Uniprot)		MRAAAHHHHLPPLLCASTFHITRIRSPAAQHTPIRNAVRRGTRTNSTAAAVNVSAYSFAAPPLTNPYAYAASPSPSSAPSMRTVGVAAAAAAMSTVHAASVTNSGAAAHTWTNGGRGGHGAAHALTNSGRDVSLVLLTVACTLLVVTIVLLIVGVRLLKRFAAAVAAAEGARGQDILSNNLSAGEAAAYISVGIVDDDDEAALHTDNGDSRTQLVEYADEREPLLHHVRGRGGGAGRHRRSASRQHQQPGRRTTLAVFEALSILLGVSSTPPTADASSHGAAAAPRRRSRSCQAGSSAVPTPENQPALRSSPQQQRHAGRRAVPDALAADENSRGAFRSGPQPTWHSNGSL-SRSGAARKCDEAAVAPASASPAP-ASHPAAAPGSSAAPATADHGATPPSGNSQLPVFTTTTEKDMVVYNTTHNSRYRLLQRIGIGAFSSVYLVQHKTTGKQYALKYILCKGDRERLAALRECEVIYSLQGHPQVIRIVDMFMSYQFQRASPSPTVAGSPTAAATNSACKEQASGQQGLRSFPGVPPSAPAAPAAALAPS---AIATPALAPASAAPASTYTTSVAGRLKGLNDAALTKAAMESSTESRAAAHSEADDGHVDFSCVDRDRYSEGRWRGSRPRVRP-SVEGVACGACMVNVDHASDVENGESAYSEHQQPQQ-PGKLSMRASSVCCPRPLPHSVQHTSQSSSSVHPTLSAAASASTAPATASSSSALAGSSYVPAQLCAAAGGGAQGCGHVPSQSAHHSSTTASAARAAATGSLSPPRDEAHADQPHLCCHAIDVPDAVVHDESDATAPVNASARCCAAHSTTTTAASMHPCFPSTTRNATVSRSSEASHEPGTLEDYDGGDGVHSGSDSRRRAEQGQSATGERAKPALQSRRASSEGRGSDGADDGHADIEAGREERRTELCGDADADEMHSCKGSDARSGATSSSGADEEPIQPIHRIFVPPPYMHPPLNGMASAPRSCSICSNNSVSYAGTGNGAASVLRPQSRTCATGGESPTSHHLYSAFPTAAAGGALAVVGPETANGSTAPAPVRRIAERPDVGSLSETASPPPFAAASASLTSSSPSPSAAVNLRHTAGSLVSTSTLPHQQQQQHPQPIPSSVTSYAPARAAVSSADVKSAATGAPAVQAPIRYKDFVLSPTTVTAHAAASWTPVPATQANALVDGQTHRQPADRGGSPAPPPCAASARVGSGAAGAGATGLTVARPTDECVNPYLERARGREPVPPPRTSYAPGGGVRYNSLTVPYVAAPTTLQAAAKGFPAQSSSPSSSLTLSASGTGVSAFDERKAGAGQGRRFEVTGADSSSQDSDASMPASQAARLTASRSLPSTAPAAATVVRNTYAPLRYGNVVQSNAASPATSSMASSSLMPPPSPSLQKQLPQPPSAACPAAAAPTVGSGRLSVCGVLRTARAGQQGEREDWDDGKPRVSASWPAKDAGLVSTQAPPLLPLPGLANQTSGAYFLRSVGRVNGAGAVPRAATPRAPYGEGRPPAAAAAQDEAPSPTRPLYTNLGVLIAGPSMTADPATATTTHVLRTGVQPPSPRHPRSNSYAGDDADRKRQRGYSNVGLTGAAPSEVRYTNAGSPNLWNAYNAGASPASAASAAAVAALTGLSPRIGAKTPTAACAGESNINDGKSSKTTHTNSSSSHLQDVCDTGYLCLVMEHHPMGDLCRYALRAQHELEMRRHRQKQSQSQALARSSLMSVGILQPITSPATATTQSRTCTSERSSAQQPQAPTKNATERDGGGTGAEAGESTSPLSLRPLSLTHGGAAGSAAAALSLLAAAADATWTVKV----AMSRTDLHPALSAGVGGRGNTSGSHTAGGTDGDERATDFDTQRAA----SVAVD-PTSENPLTEAQLLSIAYQLASVLDHMHQQNPPIVHRDLK-PENILIKGELIDYLDLPLSAVLASTNNTVHCGGKDDALGKSSVSPMTPPFTTPAAVIDAAASSLTSLP-------PIRITRAVV----PIVLIDFGLAILQDTHGRS----HGSRGGGTRPYIAPESWKG----D--TC---T-ASDVWSLGCVLYALATCR--LVAEDVRIM--S-Q---E--AK-R------D----GFA-----------------------SR---------------------------------------M---------L--KD--IIAHKYSLAFASFVVSLLVVDPAKRPTAAQAARCFCVADG-DI----------CFDLSSPFFSNVLDL--------------------------------------------------
46	Fugue	73.06	18%	-60	- C1 -	-	4DN5		M3K14_HUMAN	A:[8-351]	-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SVEEYLVHALQGSVSSGQAHSLTSLAKTWAARGSRSREPSPKTEDNEGVLLTEKLKPVDYEYREEVHWATHQLRL-------GRGSFGEVHRMEDKQTGFQCAVKK----VRLEVFRAEELMACAGLTSPRIVPLYGAVREGPWVNIFMELLEGG----SLGQL-VKEQGCLPEDRALYYLGQALEGLEYLHSRR--ILHGDVK-ADNVLLSSD----------------------GSH-------------------------------------------------------AALCDFGHAVCLQIPG-------------TETHMAPEVVLG----R--SC---DAKVDVWSSCCMMLHMLNGC--HPWTQFFRG--P-L---C--LK-I------A----S-------------------------EP---------------------------------------P---------P--VR--EIPPSCAPLTAQAIQEGLRKEPIHRVSAAELGGKVNRALQ-QVGGLKSPWRGEYKEPRHP----------------------------------------------------------
44	Fugue	62.09	20%	-10	- C1 -	-	1TKI	-	TITIN_HUMAN	A:[18-338]	----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KELYEKYMIAEDLGRGEFGIVHRCVETSSKKTYMAKFVKVKGTDQVLVKKEISILNIARHRNILHLHESFESMEELVMIFEFISGL----DIFERINTSAFELNEREIVSYVHQVCEALQFLHSHN--IGHFDIR-PENIIYQ------------------------------------------------------------------------TRRSS----TIKIIEFGQARQLKPGDNF----RLLFT--APEYYAPEVHQH----D--VVS--T-ATDMWSLGTLVYVLLSGINPFLAETNQQI--I-E---N--IM-N------A----EYT--------------------------------------------------------------------------F--DE--EAFKEISIEAMDFVDRLLVKERKSRMTASEALQHPWLKQK-IE----------RVSTKVIRTLKHRRYYHTLIKKDLNMVVSAARISCGGAIRSQKGVSVAKVKVASI----------
34	HHSearch	61.45	25%	-	- C1 -	-	4PDP	-	?	B:[249-471]	----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QKLNHPRIVRLKGFYED--S-------------YYMVMEFVSGG----DLMDF-VAAHGAVGEDAGREISRQILTAIKYIHSMG--ISHRDLK-PDNILIEQDDP------------------------------------------------------------------------V----LVKITAFGLAKVQ-----------------TLAYVAPEVI-------NEYS---S-LVDMWSMGCLVYVILTGH--LPFSGSTQDQLY-K---Q--IG-R------G----SYH--------------------------------------------------------------------------E--GP--LKDFRISEEARDFIDSLLQVDPNNRSTAAKALNHPWIKM-------------------------------------------------------------------------------
52	Fugue	60.35	13%	-35	- C1 -	-	4BTF		MLKL_MOUSE	A:[7-460]	-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DKLGQIIKLGQLIYEQCEKMKYCRKQCQ-RLGNRVHGLLQPLQRLQAQGKKNLPDDITAALGRFDEVLKEANQQIEKFILFHEVNEKLRDVWEELLLLLQV--PASWQQEDRQDAEEDGNENMKVILMQL----QISVEEINKTLKQC--SIPQDLQIKEIPKEHLGPPWTKLKTSKMS----TIYRG-EYHRSPVTIKVFNNPQAESVGIVRFTFNDEIKTMKKFDS-PNILRIFGICIDQTVKPPEFSIVME--YCELGTLRELLDREK----DLTMSVRSLLVLRAARGLYRLHHSETLHRNISSSSFLVAGGYQVKLAGFELSKTQNSI---------SRTASSTIYVSPERLKN----P--FCLYDI-KAEIYSFGIVLWEIATGK--IPFEG---C--D-S---K--KI-R------E----LVA-----------------------ED---------------------------------------K---------K--QE--PVGQDCPELLREIINECRAHEPSQRPSVDGILERLSA---------------------------------------------------------------------------------
37	HHSearch	59.78	23%	-112	- C1 -	-	2QR8	-		A:[73-283]	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GQHPNIITLKDVYDDG-------------KYVYVVTELMKGG----ELLDK-ILRQKFFSEREASAVLFTITKTVEYLHAQG--VVHRDLK-PSNILYVDESG----------------------------------------------------------------------NPE----SIRICDFGFAKQLRAENG-----LLMTPCYTANFVAPEVLER----QG-YD---A-ACDIWSLGVLLYTMLTGY--TPFANGPDD--T-P---E--EI-L------A----RIG-----------------------SGKF-------------------------------------S---------L--SG--GYWNSVSDTAKDLVSKMLHVDPHQRLTAALVLRHPWIVH-------------------------------------------------------------------------------
41	HHSearch	59.70	29%	-95	- C1 -	-	4AZF		DYRK2_HUMAN	A:[195-413]	--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QGFSLPLVRKFAHSILQCLDALHKNR--IIHCDLK-PENILLKQQGR------------------------------------------------------------------------S----GIKVIDFGSSCYEHQR--------VYTYIQSRFYRAPEVILGA---R--YG---M-PIDMWSLGCILAELLTGY--PLLPGEDEG--D-QLA-CM-IE-L------L----GMPS----------------------QKLLDASKRAKNFVSSKGYPRYCTVTTLSDVVLNGGRSRRGKLRGPPESREW--GN--ALKGCDDPLFLDFLKQCLEWDPAVRMTPGQALRHPWLR--------------------------------------------------------------------------------
50	Fugue	59.52	17%	-	- C1 -	-	3H4J	-	SNF1_SCHPO	B:[27-356]	--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SKRHIGPYIIRETLGEGSFGKVKLATHYKTQQKVALK-FISRQLLKKSDMHMRVEREISYLKLLRHPHIIKLYDVITTPTDIVM---VIEYAGGELFDYIVEK-------------KRMTEDEGRRFFQQIICAIEYCHRHKIVHR-------DLKPENLLLDDNLNVKIADFGLSNIMTDG--N----FLKTSCGSPNYAAPEVING----K--LYAG-P-EVDVWSCGIVLYVMLVGR--LPFDDEFIP--N-L---F--KK-V------N----SCV-----------------------YV---------------------------------------------------------MPDFLSPGAQSLIRRMIVADPMQRITIQEIRRDPWFNVNLPD----------YLRPMEEVQGSYADSRIVSKLGEAMGFSEDYIVEALRSDENNEVKEAYNLLHENQVIQEKLEHHH
39	HHSearch	58.20	25%	-85	- C1 -	-	5K00		MELK_HUMAN	A:[61-264]	----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KNLRHQHICQLYHVLETAN-------------KIFMVLEYCPGG----ELFDY-IISQDRLSEEETRVVFRQIVSAVAYVHSQG--YAHRDLK-PENLLFDEYH------------------------------------------------------------------------------KLKLIDFGLCAKP-----------------SLAYAAPELIQG----KSYLG---S-EADVWSMGILLYVLMCGF--LPFDDDNVM--A--------LY---------------------------------------KK---------------------------------------I---------M--RGKYDVPKWLSPSSILLLQQMLQVDPKKRISMKNLLNHPWIMQ-------------------------------------------------------------------------------
30	HHSearch	56.86	21%	-86	- C1 -	-	4IDV		M3K14_HUMAN	A:[122-330]	-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GLTSPRIVPLYGAVREGPW-------------VNIFMELLEGG----SLGQL-VKEQGCLPEDRALYYLGQALEGLEYLHSRR--ILHGDVK-ADNVLLSSDG-------------------------------------------------------------------------S----HAALCDFGHAVCLQPDGLGKSLLTGDYIPGTETHMAPEVVLG----RS-CD---A-KVDVWSSCCMMLHMLNGC--HPWTQFFRG--P-L---C--LK-I------------AS-----------------------EP---------------------------------------P---------P--VR--EIPPSCAPLTAQAIQEGLRKEPIHRVSAAELGGKVNRA--------------------------------------------------------------------------------
42	HHSearch	55.77	26%	-98	- C1 -	-	4BGQ		CDKL5_HUMAN	A:[105-299]	-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PNGVPPEKVKSYIYQLIKAIHWCHKND--IVHRDIK-PENLLISHND------------------------------------------------------------------------------VLKLCDFGFARNLSE---------------TRWYRSPELLLG----AP-YG---K-SVDMWSVGCILGELSDGQ--PLFPGESEI--D-Q---L--FT-I------QKVLGPLPSEQMKLFYSNPRFHGLRFPAVNHPQ---------------------------------------S---------L--ER--RYLGILNSVLLDLMKNLLKLDPADRYLTEQCLNHPTFQ--------------------------------------------------------------------------------
31	HHSearch	55.10	20%	-108	- C1 -	-	4G3F			A:[105-314]	----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AGLSSPRIVPLYGAVREGPW-------------VNIFMELLEGG----SLGQL-IKQMGCLPEDRALYYLGQALEGLEYLHTRR--ILHGDVK-ADNVLLSSDG-------------------------------------------------------------------------S----RAALCDFGHALCL------------DYIPGTETHMAPEVVMG----KP-CD---A-KVDIWSSCCMMLHMLNGC--HPWTQYFRG--P-L---C--LK-I------A-----S------------------------EP---------------------------------------P---------P--IR--EIPPSCAPLTAQAIQEGLRKEPVHRASAMELRRKVGKA--------------------------------------------------------------------------------
25	HHSearch	54.54	23%	-92	- C1 -	-	5J5T		M4K3_HUMAN	A:[56-266]	----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KDCKHPNIVAYFGSYLRRD-------------KLWICMEFCGGG----SLQDI-YHVTGPLSELQIAYVSRETLQGLYYLHSKG--KMHRDIK-GANILLTDNG------------------------------------------------------------------------------HVKLADFGVSAQITATI-A-------AFIGTPYWMAPEVAAVERKGG--YN---Q-LCDLWAVGITAIELAELQ--PPMFDLHPM--R-A---LFLMT-K------S----NFQ-----------------------PP---------------------------------------K---------L------KDKMKWSNSFHHFVKMALTKNPKKRPTAEKLLQHPFVT--------------------------------------------------------------------------------
32	HHSearch	54.10	22%	-88	* C1 *	-	2X0G	-	DAPK1_HUMAN	A:[66-277]	---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SI----LKEIQHPNVITLHEVYENK-------------TDVILILELVAGG----ELFDF-LAEKESLTEEEATEFLKQILNGVYYLHSLQ--IAHFDLK-PENIMLLDRNV----------------------------------------------------------------------PKP----RIKIIDFGLAHKIDFGN------EFKNIFGTPEFVAPEIVNY----EP-LG---L-EADMWSIGVITYILLSGA--SPFLGDTKQ--E-T---L--AN-V------S----A-V-----------------------NY---------------------------------------E---------F--ED--EYFSNTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIKP-------------------------------------------------------------------------------
29	HHSearch	53.50	25%	-84	- C1 -	-	1J1B		GSK3B_HUMAN	B:[150-342]	-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KQTLPVIYVKLYMYQLFRSLAYIHSFG--ICHRDIK-PQNLLLDPDT-------------------------------------------------------------------------A----VLKLCDFGSAKQLVRGE------PNVSYICSRYYRAPELIFG----ATDYT---S-SIDVWSAGCVLAELLLGQ--PIFPGDSGV--D-QLVEI--IK-VLGTPTRE----QIREMNPNYTEFKFPQIK--------AH---------------------------------------P---------W--TK--VFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDE-------------------------------------------------------------------------------
28	HHSearch	53.12	22%	-108	- C1 -	-	4NIF	-	KS6A1_HUMAN	A:[59-268]	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GQHPNIITLKDVYDDGK-------------HVYLVTELMRGG----ELLDK-ILRQKFFSEREASFVLHTIGKTVEYLHSQG--VVHRDLK-PSNILYVDESG----------------------------------------------------------------------NPE----CLRICDFGFAKQLRAEN-G----LLMTPCY---FVAPEVLKR----QG-YD---E-GCDIWSLGILLYTMLAGY--TPFANGPSD--TPE---E--IL-T-----------RIG-----------------------SG---------------------------------------K---------FTLSG--GNWNTVSETAKDLVSKMLHVDPHQRLTAKQVLQHPWVT--------------------------------------------------------------------------------
49	Fugue	52.78	17%	17	- C1 -	-	5KCV		AKT1_HUMAN	A:[20-452]	-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IVKEGWLHKRGEYITWRPRYFLLKNDGTFIGYKERPAPLNNFSVAQCQLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQRVTMNE-FEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKVLQNSRHPFL--TALKYSFQTHDRLCFVMEYANGGELFFHLSRERV---FSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCPEYLAPEVLEDNDYG---RAVDWWGLGVVMYEMMC------------GRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEK--KLSPPFKPQVTSETDTRYF----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40	HHSearch	52.28	22%	-147	- C1 -	-	5DRB		WNK1_RAT	A:[123-288]	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RFKVMKIKVLRSWCRQILKGLQFLHTRTPPIIHRDLK-CDNIFITGPT-------------------------------------------------------------------------G----SVKIGDLGLATLKRAS-------FAKAVIGTPEFMAPEMYEE----K--YD---E-SVDVYAFGMCMLEMATSE--YPYSECQNA--A-Q---I--YR-R------------VT-----------------------SG---------------------------------------V---------K--PA--SFDKVAIPEVKEIIEGCIRQNKDERYSIKDLLNHAFFQ--------------------------------------------------------------------------------
27	HHSearch	51.06	22%	-74	- C1 -	-	4Y85		M3K8_HUMAN	B:[121-326]	-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CFRHENIAELYGAVLWGE-------------TVHLFMEAGEGG----SVLEK-LESCGPMREFEIIWVTKHVLKGLDFLHSKK--VIHHDIK-PSNIVFMST-------------------------------------------------------------------------------KAVLVDFGLSVQMTEDV-Y----FPKDLRGTEIYMSPEVILC----RG-HS---T-KADIYSLGATLIHMQTGT--PPWVKRYPR--S-A---Y--PSYL------Y----IIH-----------------------KQA--------------------------------------P---------P--LE--DIADDCSPGMRELIEASLERNPNHRPRAADLLKHEALN--------------------------------------------------------------------------------
24	HHSearch	50.92	18%	-120	- C1 -	-	5O2C		WNK3_HUMAN	A:[77-287]	----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M----LKGLQHPNIVRFYDSWESILK---------GKKCIVLVTELMTSG----TLKTY-LKRFKVMKPKVLRSWCRQILKGLQFLHTRTPPIIHRDLK-CDNIFITGPT-------------------------------------------------------------------------G----SVKIGDLGLATLMRTS-------FAKSVIGTPEFMAPEMYEE----H--YD---E-SVDVYAFGMCMLEMATSE--YPYSECQNA--A-Q---I--YR-K------------VT-----------------------SG---------------------------------------I---------K--PA--SFNKVTDPEVKEIIEGCIRQNKSERLSIRDLLNHAFFAE-------------------------------------------------------------------------------
26	HHSearch	50.26	22%	-72	- C1 -	-	5IU2		M3K8_HUMAN	B:[121-326]	-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CFRHENIAELYGAVLWGE-------------TVHLFMEAGEGG----SVLEK-LESCGPMREFEIIWVTKHVLKGLDFLHSKK--VIHHDIK-PSNIVFMST-------------------------------------------------------------------------------KAVLVDFGLSVQMTEDV-Y----FPKDLRGTEIYMSPEVILC----RG-HS---T-KADIYSLGATLIHMQTGT--PPWVKRYPR--S-A---Y--PSYL------Y----IIH-----------------------KQA--------------------------------------P---------P--LE--DIADDCSPGMRELIEASLERNPNHRPRAADLLKHEALN--------------------------------------------------------------------------------