@TOME V2.3
(Mar 2018)
Ref.
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : LinJ_17_0810: (2018-03-09 )
MLSSTDSPRAHTSPTESRAAPNGLTEADTASPTRRESLVPQLAPSCVITPLQGSAASPRTLSCSRGSSEKHLNEADASHLQHPLSPNALSTQLTPSTPAKQRLLCRGAPPPSLQQQLSPALPSLARRLWNQFPVREHPSPPRGKNASDVGAEERAAAQFSMLDVFNVGNDASPQLSTLLGSPTRRSENSPALERVGSSQSSLFSTPMTRRLQGCMTKESPDYRALPAPHTSPPPLTFSTADLASVDSDKRMRNVHRRQDGWVRSPKADCRASACRQPHPGGHYSTPVASLAPPPVPQHGKISPHEPTRAASGRTASRSIGRKRDGYTRSIARFPSVSAAATPFRDLDQHLPSESAFFPTSSSEGRPHRYTVSPAKPMSPMRESKSRSTGRSPSSDAVGGARHFSSSVEKASVFKELLALDHDVVCASSEATASSRRCGRRRYSANTSPPHDGDYIGDALTASADQRMFLQIKRQSKFWPSDNTSCRFSNAVIGSTARRGVRRSSSSHTADQGGRSASSMPLSAVMGVIPREDFVHRLGGDSMQSLSSLPQLHQQQLQQLPASPSAPPLPRARTLMASIMHDHAPCSSLRPPELTPAAMEWRESAEMLVDSCCYTPSIVVEQQQQQQLLLTPLMDQPAEHSTASVQERGSLGHRVSLCSRHRRSVANGSISTARSSSSSNASRRCSCSSAPPAPAHANAESSMSLKVPALVPPPPWTPRDALYWMRNRLTLQEQEEILGYDVVYYCGPPGQPRTACGVTDRATPPPSSHHTSKETASVSSLPKNKEEVVSFTAPSSSYFPITLGMHICFRYEVLEVLGIGTFSIVVRAVDHAASPLSPERHCALKLIRRELLYQNAAQAEWAICERLKECCAAMHPCSGSNFREDASGAAADYRAGASVHRRPSASLPSALPWLSMADQRTLLFGSVLTPRSRFEYRGYHVIVFPLLGFSVRDVVELRRESREAKAGHAVSASSSLLLASAPPSQAGGQAAGTLPTKVVGSVLAQLAHALHFMHHCAHVLHGDIKPENIVFVDRSVSGRSSSINGHLAESGGAASQQPPPRPPSQQPLLQAPLPHNGDAGALPTSLSMHPFHRVCLGFPSSSLSNTAAPPPPVTHSGTVPRRSHATEHLERRFGADVGDRESPSSSTSTCSSSLPCLRAPHPPPRNIEIVDGPDRGATIMSCGHSVQHPGGEVASSSQRCPSGGDLHDQCITDGASVSLAGRSLCMTGSRTGVLTPSPHSTSTGAGLVEGSVGYVAACTTLSEAPRCSSGSSREVSPSYTTRSGHDSGGGDEASSTVTPSALTRLTYALPHAMAASTAATTSSRIALIDLGHAHHILPGTTATAFPLQSPSYRCPEMSLRLPYTTAIDMWSVGCVLYELHTGHALFPDVCDDATMLQSAVRVLGMPDAAFLTTVKTCWRKYKQHKASTVRASARAQGDVTSSDTGSQKVQLHLRQAHPQERRLAVDGEDANQDEEAIIVERCWREFIQVLNDAAGHQREHERRLKGQQESSTPPVMENSQRSPRGAALPLQNGSGCTTTWETAEQLALLKVMFPGGQVHESDQCFFLPSKCDWHRYAWVDFLLGCLYWDAGERLTATEAQVHPYLASSFSPEVAAATAVTANNAAASSGMDRKDAVDDTTMSASGVSAASSDAVPRRVVAPTIRPTHCSGLHYLRRHPLTARLLNSAAEAASQPSSPHGSDSTASDDAAPLLAPLLMNPSAIVLFELPSSNRAAPSARMWKEHQQHLSHCYDSALDIHSMLQTPAERLALSPYHNSDHRRNLFDRTGSYPFRVVFSESDQGTESSVVVSAESSVRGNLAGTQKPRNDDQTSAVMVLPLN
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690.......700.......710.......720.......730.......740.......750.......760.......770.......780.......790.......800....---...810.......820.......830.......840.......850------........860.......870.......880.......890.......900.......910....----...920.......930.......940---.....-...950.......960.......970....---...980..----------.....990.----------......1000......1010.-.....1020......1030......1040......1050......1060..-....1070......1080......1090......-1100......1110......1120--........1130..-----...--.1140......1150......1160......1170......1180--......1190......1200.......1210......1220......1230-........1240......1250......1260......1270......1280---.-------....--------------.1290.....-------.1300......1310----..------......----------------.1320......1330......1340......1350......1360......1370......1380......1390----.........1400..------.---...1410......1420.--.....1430.......1440......1450......1460......1470......1480......1490......1500......1510......1520......1530......1540......1550......1560......1570......1580......1590......1600......1610......1620......1630......1640......1650......1660......1670......1680......1690......1700......1710......1720......1730......1740......1750......1760......1770......1780......1790......1800......1810......1820......1830.....
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MLSSTDSPRAHTSPTESRAAPNGLTEADTASP
T
R
R
E
S
L
V
P
QLAP
S
C
V
I
TPLQGSAASP
R
T
L
S
CSRGSSEKHL
N
E
A
D
A
S
H
L
QHPLSPNALSTQLTPST
P
A
K
Q
R
L
L
CRGAPP
P
S
L
Q
Q
Q
L
S
P
A
L
P
S
L
A
R
R
L
W
N
QFPVREHPSPPRGKNASDVG
A
E
E
R
A
A
A
Q
F
S
M
L
D
V
F
NVGNDAS
P
Q
L
S
T
L
LGSPTRRSEN
S
P
A
L
E
R
VGSS
Q
S
S
L
FST
P
M
T
R
R
L
Q
G
C
MTKESPDYRALPAPHTSPPP
L
T
FSTADLASVD
S
D
K
R
M
R
N
V
H
RRQDGWVRSPKA
D
C
R
A
S
ACRQPHPGGHYSTPVASLAPPPVPQHGKISPHEPTRAASGR
T
A
S
R
SIGRKRDGY
T
R
S
I
ARFPSVSAAAT
P
F
R
D
L
D
Q
HLPSESAFFPTSSSEGRP
H
R
Y
TVSPAKPMS
P
M
R
E
SKSRSTGRSPSSDAVGG
A
R
H
F
S
SS
V
E
K
A
S
V
F
K
E
L
L
ALDHDVVCASSEAT
A
S
S
R
R
CGRRRYSANTSPPHDG
D
Y
IG
D
A
LTASAD
Q
R
M
F
L
Q
I
KRQSKFWPSDNTS
C
R
FSNAVI
G
S
T
A
R
RGVRRSSSSHTADQGGRSASSM
P
L
S
A
V
M
GVI
P
R
E
D
F
V
H
R
LGG
D
S
M
Q
S
L
S
S
L
P
Q
L
H
Q
Q
Q
L
Q
QLPASPSAPPL
P
R
A
R
T
L
M
A
S
I
M
HDHAPCSSLRPPEL
T
P
A
A
M
E
W
R
E
S
A
E
M
L
V
D
SCCYT
P
S
I
V
V
E
Q
Q
Q
Q
Q
Q
L
L
LTPLMDQPAEHS
T
A
S
V
Q
E
R
GSLG
H
R
V
S
L
C
S
R
H
R
R
S
VANGS
I
S
TARSSSSSNASRRCSCSSAPPAPAHANAESSM
S
L
KVPALVPPPPWTP
R
D
A
L
Y
W
M
R
N
RL
T
L
Q
E
Q
E
EILG
Y
D
V
V
Y
Y
CGPPGQPRTACGVTDRATPPPSSHHTSKETASVSSLPK
N
K
E
E
V
V
S
F
TAPSS
S
Y
F
P
I
T
L
G
M
H
I
---
C
F
R
Y
E
V
L
E
V
LG
I
G
T
F
S
I
V
V
R
A
V
D
HAASPLS
P
E
R
H
C
A
L
K
L
I
R
R
E
L
L
-------
Y
QNA
A
Q
A
E
W
A
I
C
E
R
L
K
E
C
C
A
AMHPCSGSNFREDASGAAADYRAGASVHRRPSASLPSAL
P
W
L
SMA----DQ
R
T
L
L
F
GSVLTPRSR
F
E
YR
G
Y
H
V
I
----
V
F
PLL-G
F
S
V
R
D
V
V
E
L
R
R
E
S
R
EAKAG
H
A
VSASS
S
L
L
---
L
ASAPPSQ----------AGGQAAGT
L
----------
P
T
K
V
V
G
S
V
L
A
Q
L
A
H
A
L
H
F
M
H
H
-
C
A
H
V
LHGDIKPE
N
I
V
F
V
DRSVSGRSSSIN
G
H
LAESGGAASQQPPPRPPSQQ-PLLQAPLPHNGDAGALPTSLSMH
P
F
H
R
V
C
LGFPS-SSLSNTAAPPPPVTHSGTVPR
R
----
S
H
A
T
E
H
L
E
R
R
FGAD-----VGD--RESPSSSTSTCSSSLPCLRAPHPPPR
N
I
E
I
VDGPDR
G
A
T
I
M
SCGH--SVQHPGGEVASSSQRCP-SGGD
L
H
D
Q
C
ITDGA
S
V
S
LAG
R
S
L
C
MTGSR
T
G
---
V
L
TPSPHSTSTGAGLVEGSVGY
V
A
A
C
T
T
L
SEAPRCSSGSSREVSPSYTTRSG---H-------DSGG--------------GDEASSTV
T
P
-------
S
A
L
T
R
L
T
Y
A
L
P
H
-------
A
M
------AASTAA----------------TTS
S
R
I
A
L
I
DLGHAHHILPGTTATAFPLQSPSYRCPE
M
S
LRLPYT
T
A
I
D
M
W
S
V
G
C
V
L
Y
ELHTGHALFPDVCD-------
D
A
T
M
L
Q
S
A
V
R
VLGMP------
D
---
A
A
F
L
T
T
V
K
T
C
W
R
K
Y
K
Q
H
K
--
A
S
T
VRA-SARAQGDVTSSDTGS
Q
K
V
Q
L
H
L
R
QAHP
Q
E
R
R
L
AVDGEDANQ
D
E
E
A
I
I
V
E
R
C
W
R
E
F
I
Q
V
L
N
DAAG
H
Q
R
E
H
E
R
R
LKGQQESSTPPVMENSQRSPRGAALPLQNGSGCT
T
T
W
E
T
A
E
Q
L
A
L
L
K
V
MFPGGQVHESDQ
C
F
FLPSKCD
W
H
R
Y
A
W
V
D
F
L
L
G
C
L
YWDAGERLTATEA
Q
V
H
P
Y
L
ASSFSPEV
A
A
A
T
A
V
TANNAAASSGMDRKDAVDDTTMSASGVSAASSDAVPRRVVAPTIRPTHC
S
G
L
H
Y
L
R
RH
P
L
T
A
R
L
L
N
S
A
A
E
AASQPSSPHGSDSTASD
D
A
A
P
L
L
A
P
L
LMNP
S
A
I
V
L
F
ELPSSNRAAP
S
A
R
M
W
K
E
H
Q
Q
H
L
S
H
C
Y
D
S
A
L
D
I
H
S
M
L
QT
P
A
E
R
L
A
LSPYHN
S
D
H
R
R
N
L
F
DRTGSY
P
F
R
V
V
FSESDQGTES
S
V
V
V
S
AESSVRGNLAGTQKPRNDDQT
S
A
V
M
V
L
PLN
21
HHSearch
82.02
26%
-123
- C1 -
-
5LXC
7
DYRK2_HUMAN
A:
[9-229]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
M
T
P
E
Q
A
M
K
Q
Y
M
Q
K
L
T
A
F
E
H
H
E
I
F
S
Y
P
E
I
Y
F
L
G
L
N
A
K
K
R
Q
G
M
T
G
G
--------------------------
P
N
N
G
G
Y
D
D
D
Q
G
S
Y
V
-
Q
V
P
H
D
H
V
---
A
Y
R
Y
E
V
L
K
V
I
G
K
G
S
F
G
Q
V
V
K
A
Y
D
H
K
V
H
-----
Q
H
V
A
L
K
M
V
R
N
E
K
R
-------
F
H
R
Q
A
A
E
E
I
R
I
L
E
H
L
R
K
Q
D
K
-----------------------
D
N
T
M
N
------------------------------
V
I
H
M
L
E
N
F
T
F
R
N
H
I
C
M
----
T
F
E
L
L
-
S
M
N
L
Y
E
L
I
K
K
N
K
F
--------------------------------------------
Q
G
F
----------
S
L
P
L
V
R
K
F
A
H
S
I
L
Q
C
L
D
A
L
H
K
--
N
R
I
I
H
C
D
L
K
P
E
N
I
L
L
K
Q
Q
G
R
------
S
G
I
K
V
I
D
F
G
S
S
C
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
81.20
26%
-127
- C1 -
-
4AZF
1
DYRK2_HUMAN
A:
[31-252]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
T
P
E
Q
A
M
K
Q
Y
M
Q
K
L
T
A
F
E
H
H
E
I
F
S
Y
P
E
I
Y
F
L
G
L
N
A
K
K
R
Q
G
M
T
G
-----
G
-----------------
P
----
N
N
G
G
Y
D
D
D
Q
G
S
Y
V
-
Q
V
P
H
D
H
V
---
A
Y
R
Y
E
V
L
K
V
I
G
K
G
S
F
G
Q
V
V
K
A
Y
D
H
K
V
H
-----
Q
H
V
A
L
K
M
V
R
N
E
K
R
-------
F
H
R
Q
A
A
E
E
I
R
I
L
E
H
L
R
K
Q
D
K
-----------------------
D
N
T
M
N
------------------------------
V
I
H
M
L
E
N
F
T
F
R
N
H
I
C
M
----
T
F
E
L
L
-
S
M
N
L
Y
E
L
I
K
K
N
K
F
--------------------------------------------
Q
G
F
----------
S
L
P
L
V
R
K
F
A
H
S
I
L
Q
C
L
D
A
L
H
K
--
N
R
I
I
H
C
D
L
K
P
E
N
I
L
L
K
Q
Q
G
R
------
S
G
I
K
V
I
D
F
G
S
S
C
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
HHSearch
62.80
22%
-163
- C1 -
-
4YLL
8
DYR1A_HUMAN
A:
[22-194]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
Y
I
V
K
N
G
E
K
W
---
M
D
R
Y
E
I
D
S
L
I
G
K
G
S
F
G
Q
V
V
K
A
Y
D
R
V
E
Q
-----
E
W
V
A
I
K
I
I
K
N
K
K
A
-------
F
L
N
Q
A
Q
I
E
V
R
L
L
E
L
M
N
K
H
D
T
-----------------------
E
-
K
Y
Y
------------------------------
I
V
H
L
K
R
H
F
M
F
R
N
H
L
C
L
----
V
F
E
M
L
-
S
Y
N
L
Y
D
L
L
R
N
T
N
F
--------------------------------------------
R
G
V
----------
S
L
N
L
T
R
K
F
A
Q
Q
M
C
T
A
L
L
F
L
A
T
P
E
L
S
I
I
H
C
D
L
K
P
E
N
I
L
L
C
N
P
K
R
------
S
A
I
K
I
V
D
F
G
S
S
C
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
41
HHSearch
60.67
22%
-163
- C1 -
-
4YU2
2
DYR1A_HUMAN
A:
[22-188]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
Y
I
V
K
N
G
E
K
W
---
M
D
R
Y
E
I
D
S
L
I
G
K
G
S
F
G
Q
V
V
K
A
Y
D
R
V
E
Q
-----
E
W
V
A
I
K
I
I
K
N
K
K
A
-------
F
L
N
Q
A
Q
I
E
V
R
L
L
E
L
M
N
K
H
D
T
-----------------------
E
M
K
Y
Y
------------------------------
I
V
H
L
K
R
H
F
M
F
R
N
H
L
C
L
----
V
F
E
M
L
-
S
Y
N
L
Y
D
L
L
R
N
T
N
F
--------------------------------------------
R
G
V
----------
S
L
N
L
T
R
K
F
A
Q
Q
M
C
T
A
L
L
F
L
A
T
P
E
L
S
I
I
H
C
D
L
K
P
E
N
I
L
L
C
N
P
K
R
------
S
A
I
K
I
V
D
F
G
S
S
C
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
53
Fugue
56.31
14%
31
- C1 -
-
5KCV
1
AKT1_HUMAN
A:
[20-452]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
V
K
E
G
W
L
H
K
R
----
G
E
Y
I
T
W
R
P
R
Y
F
L
L
K
NDG
T
F
I
G
Y
--
K
E
R
P
A
P
L
N
N
F
--
S
V
A
Q
C
---------
Q
L
M
K
T
E
R
P
R
P
N
T
F
I
I
R
C
L
Q
WT
T
V
I
E
R
T
F
H
V
E
T
P
E
E
R
E
E
-
W
T
T
A
I
Q
R
V
T
M
N
E
F
E
Y
L
K
L
L
G
K
G
---
T
F
G
K
V
I
---
L
V
K
E
K
A
T
G
R
Y
Y
A
M
K
I
L
K
K
V
L
Q
N
-
S
R
H
P
F
L
T
A
L
K
Y
S
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
-------
H
L
S
R
--------------
E
R
V
F
S
E
D
R
A
R
-------
F
Y
G
A
E
I
V
S
A
L
D
Y
-------
L
H
------
S
E
K
N
V
V
----------------
Y
R
D
L
K
L
E
N
L
M
L
D
K
D
G
H
I
K
I
----
T
D
F
G
L
C
-
P
E
Y
L
A
P
E
V
L
E
D
N
D
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
R
L
P
F
Y
N
Q
D
H
-------
E
K
L
F
E
L
I
L
M
E
E
I
R
F
P
------
R
TLG
P
E
A
K
S
L
L
S
G
L
L
K
K
D
P
K
Q
R
LG
G
G
S
E
D
A
-
K
E
I
M
Q
H
R
F
F
A
G
I
V
W
Q
H
V
Y
E
K
K
L
S
P
P
F
K
P
Q
V
T
S
E
T
D
T
R
Y
F
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
50
Fugue
56.16
12%
23
- C1 -
-
2ACX
1
GRK6_HUMAN
A:
[14-532]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
A
R
K
G
K
S
K
K
W
R
Q
M
L
Q
F
P
-
H
I
S
Q
C
-
E
E
L
R
L
S
L
E
R
D
Y
H
S
L
C
E
R
N
P
I
G
R
L
L
F
R
E
F
C
A
T
R
P
E
L
S
R
C
V
A
F
L
D
G
V
A
E
Y
E
V
T
P
D
D
K
R
K
----
A
C
G
R
N
L
T
Q
N
F
L
S
H
T
-----
G
P
D
LI
P
E
V
P
R
Q
L
V
T
N
C
T
Q
R
L
E
Q
G
P
C
K
D
L
F
Q
E
L
T
R
L
T
H
E
Y
L
S
V
A
P
F
A
D
Y
L
D
--
S
I
Y
F
N
R
F
L
Q
W
K
W
L
E
R
Q
P
V
T
K
N
T
F
R
Q
Y
R
V
L
G
K
G
G
F
---
G
E
V
C
A
C
Q
V
R
A
T
G
K
M
Y
A
C
K
K
L
E
K
K
R
I
K
K
R
K
G
E
A
M
A
L
N
E
K
Q
I
L
E
K
V
N
S
R
F
V
V
S
L
A
Y
A
Y
E
T
K
D
A
L
C
L
V
L
T
---
L
-------
M
N
G
G
D
L
K
F
H
I
Y
HMGQ
A
G
F
P
E
A
R
A
V
F
Y
A
A
-------
E
I
C
C
G
L
E
D
L
H
R
E
-------
R
I
VYRDLK
P
E
N
I
L
L
----------------
D
D
H
G
H
I
R
I
S
D
L
G
L
A
V
H
V
P
E
G
Q
T
I
K
G
R
V
G
-
T
V
G
Y
M
A
P
E
V
V
K
N
E
R
Y
T
F
S
P
D
W
W
A
L
G
C
L
L
Y
E
M
I
A
G
Q
S
P
F
Q
Q
R
K
K
K
I
K
R
E
E
V
E
R
L
V
K
E
V
P
E
E
Y
S
E
R
F
------
S
---
P
Q
A
R
S
L
C
S
Q
L
L
C
K
D
P
A
E
R
--
L
G
C
R
G
G
S
A
R
E
V
K
E
H
P
L
F
K
K
L
N
F
K
R
L
G
A
G
M
L
E
P
P
F
K
P
D
P
Q
A
I
Y
C
E
P
T
D
Q
D
F
Y
Q
K
F
A
T
G
S
V
P
I
P
W
Q
N
E
M
V
E
T
E
C
F
Q
E
L
N
V
F
G
L
D
G
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
HHSearch
51.90
27%
-121
- C1 -
-
4AU8
1
CDK5_HUMAN
A:
[4-155]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
---
S
Q
K
Y
E
K
L
E
K
I
G
E
G
T
Y
G
T
V
F
K
A
K
N
R
E
T
H
-----
E
I
V
A
L
K
R
V
-------------
P
S
S
A
L
R
E
I
C
L
L
K
E
L
K
-----------------------------
H
K
N
------------------------------
I
V
R
L
H
D
V
L
H
---
K
L
T
L
----
V
F
E
F
C
-
D
Q
D
L
K
K
Y
F
D
S
C
N
---------------------------------------------
G
D
L
----------
D
P
E
I
V
K
S
F
L
F
Q
L
L
K
G
L
G
F
C
H
S
--
R
N
V
L
H
R
D
L
K
P
Q
N
L
L
I
N
R
N
G
E
--------
L
K
L
A
D
F
G
L
A
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
46
Fugue
50.42
14%
3
- C1 -
-
1TKI
-
TITIN_HUMAN
A:
[18-338]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
E
L
Y
E
K
Y
M
I
A
E
D
L
G
R
G
E
F
G
I
---
V
H
R
C
V
E
T
S
S
K
K
T
Y
M
A
K
F
V
K
V
K
G
T
D
Q
V
L
V
K
K
E
I
S
I
L
N
I
A
R
H
R
N
I
L
H
L
H
E
S
F
E
S
---
M
E
E
L
V
M
I
F
E
F
I
S
--------------
G
L
D
I
F
E
R
I
N
T
SA
F
E
L
N
E
R
E
I
V
S
Y
V
H
Q
V
C
E
-------
A
L
------
Q
F
L
H
S
H
NIGHFDIRPENIIYQT
R
R
S
S
T
I
K
I
I
E
F
G
Q
A
R
Q
L
K
P
G
D
N
F
R
L
L
F
-
T
A
P
E
Y
Y
A
P
E
V
H
Q
H
D
V
V
S
T
A
T
D
M
W
S
L
G
T
L
V
Y
V
L
L
S
G
I
N
P
F
L
A
E
T
N
-------
Q
Q
I
I
E
N
I
M
N
A
E
Y
T
F
D
------
E
---
E
A
F
--------------
K
--
E
I
S
I
E
A
-
M
D
F
V
D
R
L
L
V
K
E
R
K
S
R
M
T
A
S
E
A
L
Q
H
P
W
L
K
Q
K
I
E
R
V
S
T
K
V
I
R
T
L
K
H
R
R
Y
Y
H
T
L
I
K
K
D
L
N
M
V
V
S
A
A
R
I
S
C
G
G
A
--
I
R
S
Q
K
G
V
S
V
A
K
V
K
V
A
S
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
51
Fugue
50.33
12%
11
- C1 -
-
3C4Z
1
RK_BOVIN
A:
[31-533]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
D
R
K
Y
L
A
R
L
K
L
P
P
L
S
K
C
E
A
L
R
E
S
L
D
L
G
F
E
G
M
C
L
E
Q
P
I
G
K
R
L
F
Q
Q
F
L
R
T
H
E
Q
H
G
P
A
L
Q
L
W
K
D
I
E
D
Y
D
T
A
D
D
A
L
R
P
Q
K
A
Q
A
L
R
A
A
Y
L
-------
E
P
Q
A
Q
L
F
C
S
F
L
D
A
E
T
V
A
R
A
R
-----
A
G
G
L
F
Q
P
L
L
R
A
V
L
A
H
L
G
Q
A
P
F
Q
E
F
L
D
S
L
Y
F
L
R
F
L
Q
W
K
W
L
E
A
QPM
G
E
D
W
F
L
D
F
R
V
L
G
R
G
G
F
G
E
V
F
A
C
Q
M
K
ATG
K
L
Y
A
C
K
-
K
L
N
K
K
R
L
K
K
R
K
G
Y
Q
G
A
M
V
E
K
K
I
L
A
K
V
H
S
R
F
IVS
L
A
Y
A
F
E
T
K
T
D
L
C
L
V
M
TIM
N
G
G
D
I
R
Y
H
I
YNVDED
N
P
G
F
Q
E
P
R
A
I
F
Y
T
A
Q
I
V
S
G
L
E
H
L
H
Q
--
R
N
I
I
Y
R
D
L
K
P
E
N
-
V
L
L
D
D
D
G
N
V
R
I
S
D
L
G
L
A
V
E
L
K
A
G
Q
T
K
T
K
G
Y
A
G
T
P
G
F
M
A
P
E
L
L
L
G
E
E
Y
D
F
S
V
D
Y
F
A
L
G
V
T
L
Y
E
M
I
A
A
R
G
P
F
R
A
-
R
G
E
K
V
E
N
K
E
L
K
Q
R
V
L
E
Q
A
V
T
Y
P
DKFS
P
A
S
K
D
F
C
E
A
L
L
Q
K
D
-----
P
E
K
--
R
L
G
F
R
D
G
S
C
D
G
L
R
T
H
P
L
F
R
D
I
S
W
R
Q
L
E
A
G
M
L
T
P
P
-------------
F
V
P
D
S
R
T
V
Y
A
K
N
G
A
F
S
G
-
V
A
F
E
K
A
D
T
E
F
F
Q
E
F
A
S
G
T
C
P
I
P
W
Q
E
E
M
I
E
T
G
---
V
F
G
D
L
N
V
W
R
P
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
HHSearch
49.08
24%
-95
- C1 -
-
2QR8
-
A:
[19-168]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
F
---
T
D
G
Y
E
V
K
E
D
I
G
V
G
S
Y
S
V
C
K
R
C
I
H
K
A
T
N
-----
M
E
F
A
V
K
I
I
D
K
S
K
R
----------
D
P
T
E
E
I
E
I
L
L
R
Y
G
----------------------------
Q
H
P
N
------------------------------
I
I
T
L
K
D
V
Y
D
D
G
K
Y
V
Y
V
----
V
T
E
L
M
K
G
G
E
L
L
D
K
I
L
R
Q
----------------------------------------------
K
F
F
----------
S
E
R
E
A
S
A
V
L
F
T
I
T
K
T
V
E
Y
L
H
A
--
Q
G
V
V
H
R
D
L
K
P
S
N
I
L
Y
V
D
E
S
G
----
N
P
E
S
I
R
I
C
D
F
G
F
A
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
HHSearch
48.51
26%
-68
- C1 -
-
2WEL
6
KCC2D_HUMAN
A:
[2-158]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
---
T
D
E
Y
Q
L
F
E
E
L
G
K
G
A
F
S
V
V
R
R
C
M
K
I
P
T
G
-----
Q
E
Y
A
A
K
I
I
N
T
K
K
L
S
A
R
----
D
H
Q
K
L
E
R
E
A
R
I
C
R
L
L
K
-----------------------------
H
P
N
------------------------------
I
V
R
L
H
D
S
I
S
E
E
G
F
H
Y
L
----
V
F
D
L
V
T
G
G
E
L
F
E
D
I
V
A
R
----------------------------------------------
E
Y
Y
----------
S
E
A
D
A
S
H
C
I
Q
Q
I
L
E
S
V
N
H
C
H
L
--
N
G
I
V
H
R
D
L
K
P
E
N
L
L
L
A
S
K
S
K
-----
G
A
A
V
K
L
A
D
F
G
L
A
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
48
Fugue
47.60
15%
-18
- C1 -
-
4DN5
7
M3K14_HUMAN
A:
[8-351]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
V
E
E
Y
L
V
H
A
L
Q
G
S
-----
V
S
S
--
G
Q
A
H
S
L
T
S
L
A
K
T
W
A
A
R
G
S
R
S
R
E
P
S
P
K
T
E
D
N
E
G
V
L
L
T
E
K
L
K
P
V
D
Y
E
--
Y
R
E
E
V
H
W
A
T
H
Q
L
R
L
G
R
G
-
S
F
G
E
V
H
-
R
M
E
D
K
Q
T
G
F
Q
C
A
V
K
K
V
R
L
E
V
F
R
A
E
---
E
L
M
A
C
A
G
L
T
S
P
R
I
V
P
L
Y
G
A
V
R
E
G
P
W
V
N
I
F
M
E
--
L
L
E
G
G
S
L
G
Q
L
V
K
E
Q
G
C
L
P
-------------------------------
E
D
R
A
L
Y
Y
L
G
-------
Q
A
L
E
G
L
E
Y
L
H
S
R
RILHGDV
K
A
------
D
N
V
L
L
S
----------------
S
D
G
S
H
A
A
L
C
D
F
G
H
A
V
C
L
Q
I
P
G
T
--------
E
T
H
M
A
P
E
V
V
L
G
R
S
C
D
A
K
V
D
V
W
S
S
C
C
M
M
L
H
M
L
N
G
C
H
P
W
T
Q
F
F
R
-------
G
P
L
C
L
K
I
A
S
E
P
P
P
V
R
EIPPSC
A
---
P
L
T
A
Q
A
I
Q
E
G
L
R
K
E
P
I
H
R
--
V
S
--
A
A
-
E
L
G
G
K
V
N
R
A
L
Q
Q
V
G
G
L
K
S
P
W
R
G
E
Y
K
E
P
R
H
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
46.97
25%
-121
- C1 -
-
1TKI
-
TITIN_HUMAN
A:
[19-169]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
L
---
Y
E
K
Y
M
I
A
E
D
L
G
R
G
E
F
G
I
V
H
R
C
V
E
T
S
S
K
-----
K
T
Y
M
A
K
F
V
K
V
K
G
T
-------
D
Q
V
L
V
K
K
E
I
S
I
L
N
I
A
R
-----------------------------
H
R
N
------------------------------
I
L
H
L
H
E
S
F
E
S
M
E
E
L
V
M
----
I
F
E
F
I
S
G
L
D
I
F
E
R
I
N
T
S
A
---------------------------------------------
F
E
L
----------
N
E
R
E
I
V
S
Y
V
H
Q
V
C
E
A
L
Q
F
L
H
S
--
H
N
I
G
H
F
D
I
R
P
E
N
I
I
Y
Q
T
R
R
S
------
S
T
I
K
I
I
E
F
G
Q
A
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
HHSearch
45.39
24%
-103
* C1 *
-
3C0G
1
CSKP_HUMAN
B:
[22-181]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
---
E
D
V
Y
E
L
C
E
V
I
G
K
G
P
F
S
V
V
R
R
C
I
N
R
E
T
G
-----
Q
Q
F
A
V
K
I
V
D
V
A
K
F
T
S
SPGL-
S
T
E
D
L
K
R
E
A
S
I
C
H
M
L
K
-----------------------------
H
P
H
------------------------------
I
V
E
L
L
E
T
Y
S
S
D
G
M
L
Y
M
----
V
F
E
F
M
D
G
A
D
L
C
F
E
I
V
K
R
A
D
------------------------------------------
A
G
F
V
Y
----------
S
E
A
V
A
S
H
Y
M
R
Q
I
L
E
A
L
R
Y
C
H
D
--
N
N
I
I
H
R
D
V
K
P
H
C
V
L
L
A
S
K
E
N
-----
S
A
P
V
K
L
G
G
F
G
V
A
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38
HHSearch
45.30
24%
-105
- C1 -
-
3C0I
1
CSKP_HUMAN
A:
[21-181]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
F
---
E
D
V
Y
E
L
C
E
V
I
G
K
G
P
F
S
V
V
R
R
C
I
N
R
E
T
G
-----
Q
Q
F
A
V
K
I
V
D
V
A
K
F
T
S
SPGL-
S
T
E
D
L
K
R
E
A
S
I
C
H
M
L
K
-----------------------------
H
P
H
------------------------------
I
V
E
L
L
E
T
Y
S
S
D
G
M
L
Y
M
----
V
F
E
F
M
D
G
A
D
L
C
F
E
I
V
K
R
A
D
------------------------------------------
A
G
F
V
Y
----------
S
E
A
V
A
S
H
Y
M
R
Q
I
L
E
A
L
R
Y
C
H
D
--
N
N
I
I
H
R
D
V
K
P
H
C
V
L
L
A
S
K
E
N
-----
S
A
P
V
K
L
G
G
F
G
V
A
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
HHSearch
43.94
28%
-24
- C1 -
-
1UNL
1
CDK5_HUMAN
A:
[2-149]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
K
Y
E
K
L
E
K
I
G
E
G
T
Y
G
T
V
F
K
A
K
N
R
E
T
H
-----
E
I
V
A
L
K
R
V
R
L
D
D
D
DEG----
V
P
S
S
A
L
R
E
I
C
L
L
K
E
L
K
-----------------------------
H
K
N
------------------------------
I
V
R
L
H
D
V
L
H
S
D
K
K
L
T
L
----
V
F
E
F
C
-
D
Q
D
L
K
K
Y
F
D
S
C
N
---------------------------------------------
G
D
L
----------
D
P
E
I
V
K
S
F
L
F
Q
L
L
K
G
L
G
F
C
H
S
--
R
N
V
L
H
R
D
L
K
P
Q
N
L
L
I
N
R
N
G
E
--------
L
K
L
A
N
F
G
L
A
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
44
HHSearch
41.71
26%
-78
- C1 -
-
1KOB
-
?
A:
[49-199]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
---
Y
D
Y
Y
D
I
L
E
E
L
G
S
G
A
F
G
V
V
H
R
C
V
E
K
A
T
G
-----
R
V
F
V
A
K
F
I
N
T
P
Y
P
L
------
D
K
Y
T
V
K
N
E
I
S
I
M
N
Q
L
H
-----------------------------
H
P
K
------------------------------
L
I
N
L
H
D
A
F
E
D
K
Y
E
M
V
L
----
I
L
E
F
L
S
G
G
E
L
F
D
R
I
A
A
E
D
---------------------------------------------
Y
K
M
----------
S
E
A
E
V
I
N
Y
M
R
Q
A
C
E
G
L
K
H
M
H
E
--
H
S
I
V
H
L
D
I
K
P
E
N
I
M
C
E
T
K
K
A
------
S
S
V
K
I
I
D
F
G
L
A
T
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
HHSearch
41.46
22%
-50
- C1 -
-
2X0G
-
DAPK1_HUMAN
A:
[5-166]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
Q
E
N
V
---
D
D
Y
Y
D
T
G
E
E
L
G
S
G
Q
F
A
V
V
K
K
C
R
E
K
S
T
G
-----
L
Q
Y
A
A
K
F
I
K
K
R
R
T
KSSRRGV
S
R
E
D
I
E
R
E
V
S
I
L
K
E
I
Q
-----------------------------
H
P
N
------------------------------
V
I
T
L
H
E
V
Y
E
N
K
T
D
V
I
L
----
I
L
E
L
V
A
G
G
E
L
F
D
F
L
A
E
K
----------------------------------------------
E
S
L
----------
T
E
E
E
A
T
E
F
L
K
Q
I
L
N
G
V
Y
Y
L
H
S
--
L
Q
I
A
H
F
D
L
K
P
E
N
I
M
L
L
D
R
N
V
----
P
K
P
R
I
K
I
I
D
F
G
L
A
H
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
39.75
21%
-52
- C1 -
-
4B4L
3
DAPK1_HUMAN
A:
[7-168]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
Q
E
N
V
---
D
D
Y
Y
D
T
G
E
E
L
G
S
G
Q
F
A
V
V
K
K
C
R
E
K
S
T
G
-----
L
Q
Y
A
A
K
F
I
K
K
R
R
T
KSSRRGV
S
R
E
D
I
E
R
E
V
S
I
L
K
E
I
Q
-----------------------------
H
P
N
------------------------------
V
I
T
L
H
E
V
Y
E
N
K
T
D
V
I
L
----
I
L
E
L
V
A
G
G
E
L
F
D
F
L
A
E
K
----------------------------------------------
E
S
L
----------
T
E
E
E
A
T
E
F
L
K
Q
I
L
N
G
V
Y
Y
L
H
S
--
L
Q
I
A
H
F
D
L
K
P
E
N
I
M
L
L
D
R
N
V
----
P
K
P
R
I
K
I
I
D
F
G
L
A
H
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
43
HHSearch
38.99
23%
-127
- C1 -
-
1UA2
1
CDK7_HUMAN
D:
[13-160]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
K
L
D
F
L
G
E
G
Q
F
A
T
V
Y
K
A
R
D
K
N
T
N
-----
Q
I
V
A
I
K
K
I
-------------
N
R
T
A
L
R
E
I
K
L
L
Q
E
L
S
-----------------------------
H
P
N
------------------------------
I
I
G
L
L
D
A
F
G
H
K
S
N
I
S
L
----
V
F
D
F
M
-
E
T
D
L
E
V
I
I
K
D
N
S
---------------------------------------------
L
V
L
----------
T
P
S
H
I
K
A
Y
M
L
M
T
L
Q
G
L
E
Y
L
H
Q
--
H
W
I
L
H
R
D
L
K
P
N
N
L
L
L
D
E
N
G
V
--------
L
K
L
A
D
F
G
L
A
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------