@TOME V2.3
(Mar 2018)
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : LinJ_30_1420: (2018-03-11 )
MVKLNVTLLRFMEDEDFRVLTALEMAMRNHDVAPTALVERIAQLPHGGCRKRLNNLLKHKMIHHENTMYDGYAMKYGAYDYLALRTLSKRGTCTGVGHRIGCGKESDIILVRDEAGHECVLKLQRLGRCSFRSVARNRDYKGNGRARHGESWFYLSRLASQKEYSFMKLLYDEGFPVPKPIDQNRHALLMELVPGTLLNNITELGDASKVYRRALELMVKLAESGLIHGDFNEFNLMITDDQRVIMIDFPQMISINHPNASELFDRDVQNLANFFHRRFKVDTTWFPSLEKDVVRKGELDKQVYASGHFTRKQQEDLERLMLEGFQRSEKSDDEAGSQVRDSDASDDDGDENASQRSDIGNADVDAGVAGKFTSIPGGARGGESDEEREDSSDDDASEGRLLDEAMGAARERREGEIYARNTDRNANFLPDGKINEDHVKHQIRKNIRRKDNHDFNRHLHRNVQKGRQKQKIQRQLKSSNGGGFFD
Atome Classification :
(20 SA)
.........10.-----.......20........30--------------------------------------------.-........40........---50........60........70-----------.........-80.........--90........100..----------------....--------------------------.110-..---------------..-.....--120..---....---------.-----130.......140.-------...-.----..150.....-..--------160.......170-----.......----------180--.....----..190.......--200..--------.------....210.....-..220........230......-.240........250.......260-.-----------........270.......280.......290.......300.......310...-....----320.-----......-----330.......340.......350-........360-..-.--------------....370.......380.......390....-----...400.......410.........420-.......430.......440.......450.......460.......470.......480.....--------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
M
V
K
L
N
V
T
L
L
R
FM-----EDED
F
R
V
L
T
A
L
E
M
A
M
RNH---------------------------------------------D-V
A
P
T
A
L
V
E
R
I
A
QLPH
G
G
C
---
R
K
R
L
N
N
L
L
K
H
K
M
IHHENTMYD------------GY
A
M
KYGA
Y
-
D
-
Y
L
A
L
R
T
L
SK--RGTCTGVGHRIGCGK----------------ES
D
I
--------------------------
I
L
---
V
R---------------DE-AG
H
E
C
--
V
L
K
L
Q
---
R
LG
R
---------
C
-----
S
F
R
S
V
ARNRDYKGN-------GRA-R----HGE
S
W
F
Y
L
S
R
-
L
A--------SQ
K
E
Y
S
F
M
K
L
L
Y
D-----EGFPVPK----------PID--QN
R
H
A
----
L
L
M
E
LV
P
G
T
L
L
N
--
N
I
T
EL--------G------
D
A
S
K
V
Y
R
R
A
L
E
L
-
M
V
K
L
-
A
ESGLIHGDFN
E
F
N
L
M
I
-TD-D
Q
R
V
I
M
IDF
P
Q
M
I
SINHP
N
A
---
S
-----------
E
L
F
D
R
D
V
Q
N
L
A
N
F
F
H
R
RFKVDTTWFP
S
L
E
K
D
V
V
RKGELDKQVYASGHFT
R
K
Q
Q
E
-
D
L
E
R
----
L
M
L
E
-----
G
F
QRSE-----KSDDEAGSQVRDSDASDDDGDE--N
A
S
Q
RSDIGNA-DV-D--------------AGVAGKFTSIPGGARGGESDEEREDSSDDDA-----SEG
R
L
L
D
E
A
M
G
A
A
R
--
E
RREG
E
I
Y
A
RNT-DRNANFLPDGKI
N
E
D
H
V
K
H
Q
I
R
K
N
IRRKDNH
D
F
N
R
H
L
H
R
N
V
Q
K
G
R
Q
K
Q
K
I
Q
R
Q
L
KSSN-GGGFFD--------------------------------------
52
Fugue
88.44
23%
-148
- C4 -
-
1TQM
1
RIO2_ARCFU
A:
[1-282]
--
M
N
I
A
E
L
Y
G
K
M
-----
G
K
H
S
W
R
I
M
D
A
I
F
K
N
L
W
D
Y
---------------------------------------------
E
-
Y
V
P
L
Q
L
I
S
S
H
A
R
I
G
E
E
K
A
---
R
N
I
L
K
Y
L
S
D
L
R
V
V
Q
N
R
Q
K
D
Y
E
------------
G
S
T
F
T
F
I
G
L
-
S
-
L
Y
S
L
H
R
L
V
R
--
S
G
K
V
D
A
I
G
K
L
M
G
E
G
K
----------------
E
S
A
V
--------------------------
F
N
---
C
Y
---------------
S
E
-
K
F
G
E
C
--
V
V
K
F
H
---
K
-----------------------------------------
V
-
K
----
V
K
E
H
F
S
V
L
A
I
-
R
S
--------
A
R
N
E
F
R
A
L
Q
K
L
Q
-------
G
L
A
V
P
K
----------
V
Y
A
--
W
E
G
N
A
----
V
L
M
E
L
I
D
A
K
E
L
Y
--
R
-
V
R
V
--------
E
------
N
P
D
E
V
L
D
M
I
L
E
E
-
V
A
K
F
-
Y
H
R
G
I
V
H
G
D
L
S
Q
Y
N
V
L
V
-
S
E
-
E
-
G
I
W
I
I
D
F
P
Q
S
V
E
V
G
E
E
G
W
---
R
-----------
E
I
L
E
R
D
V
R
N
I
I
T
Y
F
S
R
T
Y
R
T
E
K
D
-
I
N
S
A
I
D
R
I
L
Q
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
85.80
25%
-143
- C4 -
-
1ZAO
2
RIO2_ARCFU
A:
[10-269]
-----------
M
-----
G
K
H
S
W
R
I
M
D
A
I
F
K
N
L
W
D
Y
---------------------------------------------
E
-
Y
V
P
L
Q
L
I
S
S
H
A
R
I
G
E
E
K
A
---
R
N
I
L
K
Y
L
S
D
L
R
V
V
Q
N
R
Q
K
D
Y
E
------------
G
S
T
F
T
F
I
G
L
-
S
-
L
Y
S
L
H
R
L
V
R
--
S
G
K
V
D
A
I
G
K
L
M
G
E
G
K
----------------
E
S
A
V
--------------------------
F
N
---
C
Y
---------------
S
E
-
K
F
G
E
C
--
V
V
K
F
H
---
K
V
G
H
---------
T
--------
K
V
K
E
----------------------------
F
S
V
L
A
-
I
R
--------
S
A
R
N
-
E
F
R
A
L
Q
K
L
-----
Q
G
L
A
V
P
K
----------
V
Y
A
--
W
E
G
N
A
----
V
L
M
E
L
I
D
A
K
E
L
Y
--
R
V
-
R
V
--------
E
------
N
P
D
E
V
L
D
M
I
L
E
E
-
V
A
K
F
-
Y
H
R
G
I
V
H
G
D
L
S
Q
Y
N
V
L
V
-
S
E
-
E
G
-
I
W
I
I
D
F
P
Q
S
V
E
V
G
E
E
G
W
---
R
-----------
E
I
L
E
R
D
V
R
N
I
I
T
Y
F
S
R
T
Y
R
T
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
85.19
25%
-146
- C4 -
-
1TQI
2
RIO2_ARCFU
A:
[10-269]
-----------
M
-----
G
K
H
S
W
R
I
M
D
A
I
F
K
N
L
W
D
Y
---------------------------------------------
E
-
Y
V
P
L
Q
L
I
S
S
H
A
R
I
G
E
E
K
A
---
R
N
I
L
K
Y
L
S
D
L
R
V
V
Q
N
R
Q
K
D
Y
E
------------
G
S
T
F
T
F
I
G
L
-
S
-
L
Y
S
L
H
R
L
V
R
--
S
G
K
V
D
A
I
G
K
L
M
G
E
G
K
----------------
E
S
A
V
--------------------------
F
N
---
C
Y
---------------
S
E
-
K
F
G
E
C
--
V
V
K
F
H
---
K
V
--------------------
K
V
K
E
---------------------------
H
F
S
V
L
A
-
I
R
--------
S
A
R
N
-
E
F
R
A
L
Q
K
L
-----
Q
G
L
A
V
P
K
----------
V
Y
A
--
W
E
G
N
A
----
V
L
M
E
L
I
D
A
K
E
L
Y
--
R
V
-
R
V
--------
E
------
N
P
D
E
V
L
D
M
I
L
E
E
-
V
A
K
F
-
Y
H
R
G
I
V
H
G
D
L
S
Q
Y
N
V
L
V
-
S
E
-
E
G
-
I
W
I
I
D
F
P
Q
S
V
E
V
G
E
E
G
W
---
R
-----------
E
I
L
E
R
D
V
R
N
I
I
T
Y
F
S
R
T
Y
R
T
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
84.05
25%
-144
- C4 -
-
1ZAR
3
RIO2_ARCFU
A:
[10-269]
-----------
M
-----
G
K
H
S
W
R
I
M
D
A
I
F
K
N
L
W
D
Y
---------------------------------------------
E
-
Y
V
P
L
Q
L
I
S
S
H
A
R
I
G
E
E
K
A
---
R
N
I
L
K
Y
L
S
D
L
R
V
V
Q
N
R
Q
K
D
Y
E
------------
G
S
T
F
T
F
I
G
L
-
S
-
L
Y
S
L
H
R
L
V
R
--
S
G
K
V
D
A
I
G
K
L
M
G
E
G
K
----------------
E
S
A
V
--------------------------
F
N
---
C
Y
---------------
S
E
-
K
F
G
E
C
--
V
V
K
F
H
---
K
V
--------------------
K
V
K
E
---------------------------
H
F
S
V
L
A
-
I
R
--------
S
A
R
N
-
E
F
R
A
L
Q
K
L
-----
Q
G
L
A
V
P
K
----------
V
Y
A
--
W
E
G
N
A
----
V
L
M
E
L
I
D
A
K
E
L
Y
--
R
V
-
R
V
--------
E
------
N
P
D
E
V
L
D
M
I
L
E
E
-
V
A
K
F
-
Y
H
R
G
I
V
H
G
D
L
S
Q
Y
N
V
L
V
-
S
E
-
E
G
-
I
W
I
I
D
F
P
Q
S
V
E
V
G
E
E
G
W
---
R
-----------
E
I
L
E
R
D
V
R
N
I
I
T
Y
F
S
R
T
Y
R
T
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
84.03
24%
-142
- C4 -
-
1ZAO
2
RIO2_ARCFU
A:
[1-277]
--
M
N
I
A
E
L
Y
G
K
M
-----
G
K
H
S
W
R
I
M
D
A
I
F
K
N
L
W
D
Y
---------------------------------------------
E
-
Y
V
P
L
Q
L
I
S
S
H
A
R
I
G
E
E
K
A
---
R
N
I
L
K
Y
L
S
D
L
R
V
V
Q
N
R
Q
K
D
Y
E
------------
G
S
T
F
T
F
I
G
L
-
S
-
L
Y
S
L
H
R
L
V
R
--
S
G
K
V
D
A
I
G
K
L
M
G
E
G
K
----------------
E
S
A
V
--------------------------
F
N
---
C
Y
---------------
S
E
-
K
F
G
E
C
--
V
V
K
F
H
---
K
V
G
H
---------
T
--------
K
V
K
E
---------------------------
F
S
V
L
A
I
-
R
S
--------
A
R
N
E
F
R
A
L
Q
K
L
Q
G
-----
L
A
--
V
P
K
----------
V
Y
A
--
W
E
G
N
A
----
V
L
M
E
L
I
D
A
K
E
L
Y
--
R
V
R
V
E
---------------
N
P
D
E
V
L
D
M
I
L
E
E
-
V
A
K
F
-
Y
H
R
G
I
V
H
G
D
L
S
Q
Y
N
V
L
V
-
S
E
--
E
G
I
W
I
I
D
F
P
Q
S
V
E
V
G
E
E
G
W
---
R
-----------
E
I
L
E
R
D
V
R
N
I
I
T
Y
F
S
R
T
Y
R
T
E
K
D
I
N
S
A
I
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
83.91
25%
-146
- C4 -
-
1TQM
1
RIO2_ARCFU
A:
[10-269]
-----------
M
-----
G
K
H
S
W
R
I
M
D
A
I
F
K
N
L
W
D
Y
---------------------------------------------
E
-
Y
V
P
L
Q
L
I
S
S
H
A
R
I
G
E
E
K
A
---
R
N
I
L
K
Y
L
S
D
L
R
V
V
Q
N
R
Q
K
D
Y
E
------------
G
S
T
F
T
F
I
G
L
-
S
-
L
Y
S
L
H
R
L
V
R
--
S
G
K
V
D
A
I
G
K
L
M
G
E
G
K
----------------
E
S
A
V
--------------------------
F
N
---
C
Y
---------------
S
E
-
K
F
G
E
C
--
V
V
K
F
H
---
K
V
--------------------
K
V
K
E
---------------------------
H
F
S
V
L
A
-
I
R
--------
S
A
R
N
-
E
F
R
A
L
Q
K
L
-----
Q
G
L
A
V
P
K
----------
V
Y
A
--
W
E
G
N
A
----
V
L
M
E
L
I
D
A
K
E
L
Y
--
R
V
-
R
V
--------
E
------
N
P
D
E
V
L
D
M
I
L
E
E
-
V
A
K
F
-
Y
H
R
G
I
V
H
G
D
L
S
Q
Y
N
V
L
V
-
S
E
-
E
G
-
I
W
I
I
D
F
P
Q
S
V
E
V
G
E
E
G
W
---
R
-----------
E
I
L
E
R
D
V
R
N
I
I
T
Y
F
S
R
T
Y
R
T
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
83.70
24%
-142
- C4 -
-
1ZAR
3
RIO2_ARCFU
A:
[2-277]
---
N
I
A
E
L
Y
G
K
M
-----
G
K
H
S
W
R
I
M
D
A
I
F
K
N
L
W
D
Y
---------------------------------------------
E
-
Y
V
P
L
Q
L
I
S
S
H
A
R
I
G
E
E
K
A
---
R
N
I
L
K
Y
L
S
D
L
R
V
V
Q
N
R
Q
K
D
Y
E
------------
G
S
T
F
T
F
I
G
L
-
S
-
L
Y
S
L
H
R
L
V
R
--
S
G
K
V
D
A
I
G
K
L
M
G
E
G
K
----------------
E
S
A
V
--------------------------
F
N
---
C
Y
---------------
S
E
-
K
F
G
E
C
--
V
V
K
F
H
---
K
V
--------------------
K
V
K
E
--------------------------
H
F
S
V
L
A
I
-
R
S
--------
A
R
N
E
F
R
A
L
Q
K
L
Q
G
-----
L
A
--
V
P
K
----------
V
Y
A
--
W
E
G
N
A
----
V
L
M
E
L
I
D
A
K
E
L
Y
--
R
V
R
V
E
---------------
N
P
D
E
V
L
D
M
I
L
E
E
-
V
A
K
F
-
Y
H
R
G
I
V
H
G
D
L
S
Q
Y
N
V
L
V
-
S
E
--
E
G
I
W
I
I
D
F
P
Q
S
V
E
V
G
E
E
G
W
---
R
-----------
E
I
L
E
R
D
V
R
N
I
I
T
Y
F
S
R
T
Y
R
T
E
K
D
I
N
S
A
I
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
80.86
24%
-144
- C4 -
-
1TQP
1
RIO2_ARCFU
A:
[15-269]
---------------------
W
R
I
M
D
A
I
F
K
N
L
W
D
Y
---------------------------------------------
E
-
Y
V
P
L
Q
L
I
S
S
H
A
R
I
G
E
E
K
A
---
R
N
I
L
K
Y
L
S
D
L
R
V
V
Q
N
R
Q
K
D
Y
E
------------
G
S
T
F
T
F
I
G
L
-
S
-
L
Y
S
L
H
R
L
V
R
--
S
G
K
V
D
A
I
G
K
L
M
G
E
G
K
----------------
E
S
A
V
--------------------------
F
N
---
C
Y
---------------
S
E
-
K
F
G
E
C
--
V
V
K
F
H
---
K
V
--------------------
K
V
K
E
---------------------------
H
F
S
V
L
A
-
I
R
--------
S
A
R
N
-
E
F
R
A
L
Q
K
L
-----
Q
G
L
A
V
P
K
----------
V
Y
A
--
W
E
G
N
A
----
V
L
M
E
L
I
D
A
K
E
L
Y
--
R
V
-
R
V
--------
E
------
N
P
D
E
V
L
D
M
I
L
E
E
-
V
A
K
F
-
Y
H
R
G
I
V
H
G
D
L
S
Q
Y
N
V
L
V
-
S
E
-
E
G
-
I
W
I
I
D
F
P
Q
S
V
E
V
G
E
E
G
W
---
R
-----------
E
I
L
E
R
D
V
R
N
I
I
T
Y
F
S
R
T
Y
R
T
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
61.46
26%
-10
- C4 -
-
3RE4
1
RIO1_ARCFU
A:
[38-241]
------------------------------------------------------------------------------------------------------------------------------------------------------
T
L
Y
K
L
S
A
--
K
G
Y
I
T
A
M
G
G
V
I
S
T
G
K
----------------
E
A
N
V
--------------------------
F
Y
A
D
G
V
F
---------------
D
G
-
K
P
V
A
M
--
A
V
K
I
Y
---
R
I
E
------------------
D
K
M
----------------
D
E
Y
-
L
----
Y
G
D
E
R
F
D
M
R
R
-
I
S
PKE
K
V
F
I
W
T
E
K
E
F
R
N
L
E
R
A
K
E
-----
A
G
V
S
V
P
Q
----------
P
Y
T
--
Y
M
K
N
V
----
L
L
M
E
F
I
G
E
D
E
L
P
AP
T
L
V
E
L
--------
G
R
E
L
K
E
L
D
V
E
G
I
F
N
D
V
V
E
N
-
V
K
R
L
Y
Q
E
A
E
L
V
H
A
D
L
S
E
Y
N
I
M
Y
-
I
D
---
K
V
Y
F
I
D
M
G
Q
A
V
T
L
R
H
P
M
A
---
E
-----------
S
Y
L
E
R
D
V
R
N
I
I
R
F
F
S
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
HHSearch
61.32
27%
-20
- C4 -
-
1ZTH
1
RIO1_ARCFU
D:
[37-253]
-----------------------------------------------------------------------------------------------------------------------------------------------------
K
T
L
Y
K
L
S
A
--
K
G
Y
I
T
A
M
G
G
V
I
S
T
G
K
----------------
E
A
N
V
--------------------------
F
Y
---
A
D
---------------
G
V
F
D
G
K
P
V
A
M
A
V
K
I
Y
---
R
I
---------------------
M
---
D
E
Y
L
Y
G
D------
E
R
F
D----------
K
E
K
V
F
-
I
W
--------
T
E
K
E
F
R
N
L
E
R
A
K
E
-----
A
G
V
S
V
P
Q
----------
P
Y
T
--
Y
M
K
N
V
----
L
L
M
E
F
I
G
E
D
E
L
P
--
A
P
T
L
V
EL
G
R
E
L
K
E
L
------
D
V
E
G
I
F
N
D
V
V
E
N
-
V
K
R
L
Y
Q
E
A
E
L
V
H
A
D
L
S
E
Y
N
I
M
Y
-
I
---
D
K
V
Y
F
I
D
M
G
Q
A
V
T
L
R
H
P
M
A
---
E
-----------
S
Y
L
E
R
D
V
R
N
I
I
R
F
F
S
K
-
Y
G
V
K
A
D
F
E
E
M
L
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
HHSearch
59.49
27%
-2
- C4 -
-
4JIN
1
RIO1_ARCFU
A:
[37-253]
-----------------------------------------------------------------------------------------------------------------------------------------------------
K
T
L
Y
K
L
S
A
--
K
G
Y
I
T
A
M
G
G
V
I
S
T
G
K
----------------
E
A
N
V
--------------------------
F
Y
---
A
D
---------------
G
V
F
D
G
K
P
V
A
M
A
V
K
I
Y
---
R
I
E
T
---------
S
-----
E
F
D
K
M
---
D
E
Y
L
Y
G
D------
E
R
F
D
M
----
R
R
I
S
P
K
E
K
V
F
-
I
W
--------
T
E
K
E
F
R
N
L
E
R
A
K
E
-----
A
G
V
S
V
P
Q
----------
P
Y
T
--
Y
M
K
N
V
----
L
L
M
E
F
I
G
E
D
E
L
P
--
A
P
T
L
V
ELGRELKE
L
------
D
V
E
G
I
F
N
D
V
V
E
N
-
V
K
R
L
Y
Q
E
A
E
L
V
H
A
D
L
S
E
Y
N
I
M
Y
-
I
---
D
K
V
Y
F
I
D
M
G
Q
A
V
T
L
R
H
P
M
A
---
E
-----------
S
Y
L
E
R
D
V
R
N
I
I
R
F
F
S
K
-
Y
G
V
K
A
D
F
E
E
M
L
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
56.90
24%
-32
- C4 -
-
1ZTF
1
RIO1_ARCFU
A:
[38-241]
------------------------------------------------------------------------------------------------------------------------------------------------------
T
L
Y
K
L
S
A
--
K
G
Y
I
T
A
M
G
G
V
I
S
T
G
K
----------------
E
A
N
V
--------------------------
F
Y
---
A
D
---------------
G
V
-
F
D
G
K
P
--
V
A
M
A
V
---
K
I
Y
R
---------
I
-----
E
T
S
E
F
D
K
M
D
E
Y
--------------
L
----
Y
G
D
E
R
F
D
M
R
R
-
I
S
PKE
K
V
F
I
W
T
E
K
E
F
R
N
L
E
R
A
K
E
-----
A
G
V
S
V
P
Q
----------
P
Y
T
--
Y
M
K
N
V
----
L
L
M
E
F
I
G
E
D
E
L
P
AP
T
L
V
E
L
--------
G
R
E
L
K
E
L
D
V
E
G
I
F
N
D
V
V
E
N
-
V
K
R
L
Y
Q
E
A
E
L
V
H
A
D
L
S
E
Y
N
I
M
Y
-
I
D
---
K
V
Y
F
I
D
M
G
Q
A
V
T
L
R
H
P
M
A
---
E
-----------
S
Y
L
E
R
D
V
R
N
I
I
R
F
F
S
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
55.89
26%
-16
- C4 -
-
4JIN
1
RIO1_ARCFU
A:
[38-241]
------------------------------------------------------------------------------------------------------------------------------------------------------
T
L
Y
K
L
S
A
--
K
G
Y
I
T
A
M
G
G
V
I
S
T
G
K
----------------
E
A
N
V
--------------------------
F
Y
A
D
G
V
F
---------------
D
G
-
K
P
V
A
M
--
A
V
K
I
Y
---
R
I
E
T
---------
S
-----
E
F
D
K
M
----------------
D
E
Y
-
L
----
Y
G
D
E
R
F
D
M
R
R
-
I
S
PKE
K
V
F
I
W
T
E
K
E
F
R
N
L
E
R
A
K
E
-----
A
G
V
S
V
P
Q
----------
P
Y
T
--
Y
M
K
N
V
----
L
L
M
E
F
I
G
E
D
E
L
P
AP
T
L
V
E
L
--------
G
RELKEL
D
V
E
G
I
F
N
D
V
V
E
N
-
V
K
R
L
Y
Q
E
A
E
L
V
H
A
D
L
S
E
Y
N
I
M
Y
-
I
D
---
K
V
Y
F
I
D
M
G
Q
A
V
T
L
R
H
P
M
A
---
E
-----------
S
Y
L
E
R
D
V
R
N
I
I
R
F
F
S
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
60
Fugue
50.84
16%
75
- C2 -
-
4M0M
3
?
A:
[13-740]
E
Q
K
V
K
T
V
T
L
S
F
L
G
TGQH
R
E
K
V
H
H
I
L
T
S
F
H
N
T
I
S
E
V
N
KDNPT
V
A
M
R
M
F
D
G
PGSEPKSGDSKDPIPGT
Y
I
Y
N
PKDN
S
K
I
L
I
S
P
-
V
I
S
Q
T
I
T
N
A
I
Q
K
L
T
G
N
L
A
---
G
E
G
I
E
H
L
L
F
E
A
V
L
Y
L
N
D
I
I
E
K
N
G
GKLPE
T
V
N
L
H
G
F
S
R
G
A
D
T
C
M
R
M
A
N
L
L
Y
Q
L
Y
P
D
I
K
V
N
L
F
L
I
D
Q
V
P
G
P
G
K
RDDPHSYTVPPNVE
H
F
E
S
T
L
M
LHEYRPGF
D
P
Q
H
SGRYVIADPEKTK
V
V
---
V
K
P
Y
Y
G
E
HNTGNRVTED
P
N
-
T
N
H
T
A
--
I
L
L
N
D
D
M
N
R
F
C
R
E
T
GSLPSVG
I
-----
S
P
P
I
I
A
R
V
G
D
K
K
E
E
-------
V
R
T
-
H
SELS
P
E
K
R
F
E
L
L
C
G
M
K
E
--------
N
E
W
G
Y
A
K
L
T
K
K
Y
H
-----
E
R
S
I
L
S
K
REDYVQDSRL
F
V
N
--
Q
E
H
R
E
----
L
F
K
Q
L
Y
P
K
S
F
N
W
--
F
F
E
K
N
--------
H
------
G
G
Q
T
K
K
E
E
V
I
V
E
-
L
K
S
L
-
S
E
D
P
R
Y
E
H
F
F
S
S
L
A
K
H
F
-
Q
I
-
N
E
N
N
I
A
G
T
L
P
E
P
S
G
I
D
R
D
E
K
---
S
SFGQPPVRD
R
L
S
Y
L
Q
H
S
L
T
S
I
A
N
Y
Y
H
Y
H
C
D
E
K
S
S
T
N
E
S
V
K
N
L
L
L
E
R
V
K
E
S
R
T
K
P
D
S
E
A
I
K
H
L
E
Q
T
M
D
E
V
R
----
Q
I
L
E
S
K
NEK
G
F
L
W
Q
Q
I
N
H
IS
P
N
A
R
Q
Y
C
E
Q
V
K
A
A
L
R
E
H
L
E
H
N
Q
VL
S
D
T
Q
K
E
E
I
R
K
A
M
D
R
M
D
N
I
V
N
DSSKD
S
Q
Q
K
Y
R
E
I
R
R
E
V
I
E
L
N
A
K
A
T
T
P
E
D
D
N
Q
L
T
R
S
H
F
Q
K
A
Y
F
EGD
T
Q
K
T
L
N
L
E
S
L
S
Q
T
L
--
N
Q
L
S
K
A
H
Y
G
E
T
S
M
T
D
K
I
T
Q
R
L
D
G
Y
K
N
R
N
W
F
W
N
S
V
K
E
V
L
N
F
F
N
I
P
L
P
K
L
H
S
E
V
K
E
Q
I
A
D
K
L
K
E
R
L
V
D
L
K
E
K
G
M
G
N
D
V
N
A
I
T
R
E
L
G
K
A
R
E
D
L
I
E
H
Y
K
K
TG
E
L
D
K
I
I
N
K
S
M
E
E
L
L
V
A
R
K
11
PsiBlast_PDB
48.22
25%
0
- C4 -
-
4AX8
1
WBDD_ECOLX
A:
[301-464]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
F
D
A
P
A
----------
V
L
A
--
H
G
E
N
A
Q
S
G
W
L
V
M
E
K
L
P
G
R
L
L
S
--
D
M
L
A
A
--------
G
EEI---
D
R
E
K
I
L
G
S
L
L
R
S
-
L
A
A
L
-
E
K
Q
G
F
W
H
D
D
V
R
P
W
N
V
M
V
-
D
A
-
R
Q
H
A
R
L
I
D
F
G
S
I
V
T
T
--
P
-----------------
S
W
P
T
N
L
V
Q
S
F
F
V
F
V
N
E
L
F
-----------------
F
N
L
P
Q
P
--
W
S
N
W
L
Y
A
V
W
Q
E
-
P
V
E
R
WN
F
V
L
L
L
A
-----
L
F
E
K
K
A
-----
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
48.11
25%
1
- C4 -
-
4AZS
1
WBDD_ECOLX
A:
[301-464]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
F
D
A
P
A
----------
V
L
A
--
H
G
E
N
A
Q
S
G
W
L
V
M
E
K
L
P
G
R
L
L
S
--
D
M
L
A
A
--------
G
EEI---
D
R
E
K
I
L
G
S
L
L
R
S
-
L
A
A
L
-
E
K
Q
G
F
W
H
D
D
V
R
P
W
N
V
M
V
-
D
A
-
R
Q
H
A
R
L
I
D
F
G
S
I
V
T
T
--
P
-----------------
S
W
P
T
N
L
V
Q
S
F
F
V
F
V
N
E
L
F
-----------------
F
N
L
P
Q
P
--
W
S
N
W
L
Y
A
V
W
Q
E
-
P
V
E
R
WN
F
V
L
L
L
A
-----
L
F
E
K
K
A
-----
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
57
Fugue
47.03
16%
-58
* C3 *
-
4GPK
-
?
B:
[9-360]
-----------
V
-----
E
E
D
V
K
G
K
L
D
E
W
L
N
A
L
V
H
L
---------------------------------------------
D
----
K
Q
Q
V
E
R
I
Y
E
E
L
Q
G
-------
E
M
K
H
V
L
D
F
E
I
I
N
Y
Y
K
L
L
Y
T
------------
R
Y
L
I
M
K
R
D
I
-
S
-
A
L
E
E
E
L
D
K
L
--
K
K
V
Y
K
K
Y
S
---------------------------------------------------------------------------------------
P
F
Q
---
K
L
L
Y
---------
M
-----
Y
G
R
G
L
L
C
C
L
Q
Y
-----------
R
W
-
K
----
D
G
L
D
Y
L
L
K
T
E
-
V
M
--------
A
K
E
Q
G
Y
H
E
T
G
L
Y
Y
-----
N
I
A
L
A
Y
T
----------
H
L
D
----
I
H
H
----
L
A
I
H
F
V
N
M
A
L
E
G
--
F
R
S
E
Y
--------
K
-----------
F
R
N
I
I
N
C
-
Q
I
L
I
-
A
V
S
Y
T
E
K
G
Q
Y
E
E
A
L
K
M
Y
-
E
S
-
I
L
R
E
---------
A
T
S
F
A
D
K
---
D
-----------
V
L
L
A
I
T
L
S
N
M
G
S
I
Y
Y
K
K
---------------------------------
G
K
Y
Q
-
Q
A
K
K
----
Y
Y
L
D
-----
S
L
Q
L
Q
K
-----
Q
I
D
-------------------------
L
N
Y
L
D
T
I
-
Y
E
-
M
--------------
A
L
V
C
I
K
L
--------------------
E
E
L
E
-----
E
A
R
T
L
I
D
K
G
I
D
A
A
K
QE
E
R
F
N
A
K
L
Y
L
L
L
M
-
L
R
Y
K
Y
F
E
E
A
K
D
Y
K
A
F
L
E
N
E
A
I
P
L
K
K
V
Y
V
E
L
A
E
H
F
S
S
L
S
R
F
E
E
S
N
R
Y
Y
R
L
V
I
D
L
M
N
D
-----------------------------------------------
13
PsiBlast_PDB
46.75
25%
0
- C4 -
-
4AZV
-
WBDD_ECOLX
A:
[301-464]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
F
D
A
P
A
----------
V
L
A
--
H
G
E
N
A
Q
S
G
W
L
V
M
E
K
L
P
G
R
L
L
S
--
D
M
L
A
A
--------
G
EEI---
D
R
E
K
I
L
G
S
L
L
R
S
-
L
A
A
L
-
E
K
Q
G
F
W
H
D
D
V
R
P
W
N
V
M
V
-
D
A
-
R
Q
H
A
R
L
I
D
F
G
S
I
V
T
T
--
P
-----------------
S
W
P
T
N
L
V
Q
S
F
F
V
F
V
N
E
L
F
-----------------
F
N
L
P
Q
P
--
W
S
N
W
L
Y
A
V
W
Q
E
-
P
V
E
R
WN
F
V
L
L
L
A
-----
L
F
E
K
K
A
-----
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
45.41
28%
-168
- C4 -
-
4Q5H
1
OSPG_SHISS
A:
[79-166]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
P
G
T
P
L
S
--
D
I
D
T
A
--------
D
------
I
P
D
N
I
E
S
L
Y
L
Q
L
-
I
C
K
L
-
N
E
L
S
I
I
H
Y
D
L
N
T
G
N
M
L
Y
D
K
E
-
S
E
S
L
F
P
I
D
F
R
N
I
Y
A
E
Y
Y
A
A
T
K
K
D
K
-----------
E
I
I
D
R
R
L
Q
M
R
T
N
D
F
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
HHSearch
41.98
17%
4
- C4 -
-
4PED
-
COQ8A_HUMAN
A:
[21-265]
-----------------------
L
K
L
G
Q
M
L
S
I
Q
-
D
---------------------------------------------
D
A
F
I
N
P
H
L
A
K
I
F
E
R
V
R
Q
S
A
D
FMP
L
K
Q
M
M
K
T
L
N
N
D
L
G
P
N
W
R
D
K
L
E
------------
Y
F
E
E
R
P
F
---------------------------
A
A
A
S
----------------
I
G
Q
V
--------------------------
H
L
---
A
R
---------------
M
K
-
G
G
R
E
V
--
A
M
K
I
Q
---
Y
P
G
V
---------
A
QS
I
N
S
D
V
N
N
L
M
A
V
L
N
M
S
N
M
LPEGLFP
E
H
L
-
I
----
D
V
L
R
R
E
L
A
L
E
-
C
D
--------
Y
Q
R
E
A
A
C
A
R
K
F
R
D
L
L
KGH
P
F
F
Y
V
P
E
----------
I
V
D
EL
C
S
P
H
V
----
L
T
T
E
L
V
S
G
F
P
L
D
--
Q
A
E
G
L
S
Q
------
E
------
I
R
N
E
I
C
Y
N
I
L
V
L
C
L
R
E
L
-
F
E
F
H
F
M
Q
T
D
P
N
W
S
N
F
F
Y
-
D
P
Q
Q
H
K
V
A
L
L
D
F
G
A
T
R
E
Y
D
R
S
F
T
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------