@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : H2AY_HUMAN: (2018-10-03 )
MSSRGGKKKSTKTSRSAKAGVIFPVGRMLRYIKKGHPKYRIGVGAPVYMAAVLEYLTAEILELAGNAARDNKKGRVTPRHILLAVANDEELNQLLKGVTIASGGVLPNIHPELLAKKRGSKGKLEAIITPPPAKKAKSPSQKKPVSKKAGGKKGARKSKKKQGEVSKAASADSTTEGTPADGFTVLSTKSLFLGQKLNLIHSEISNLAGFEVEAIINPTNADIDLKDDLGNTLEKKGGKEFVEAVLELRKKNGPLEVAGAAVSAGHGLPAKFVIHCNSPVWGADKCEELLEKTVKNCLALADDKKLKSIAFPSIGSGRNGFPKQTAAQLILKAISSYFVSTMSSSIKTVYFVLFDSESIGIYVQEMAKLDAN
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280..---.....290.......300.......310.......320.......330.......340.......350.......360.......370
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MSSRGGKKKSTKTSRSAKA
G
V
I
F
P
V
G
R
M
L
R
Y
I
K
KGHP
K
Y
R
IGVG
A
P
V
Y
M
A
A
V
L
E
Y
L
T
A
E
I
L
E
LAGNAARDNKKGRVTP
R
H
I
L
L
A
VA
N
D
E
E
L
N
Q
L
L
KG
V
T
IASGGVLPNI
H
P
E
L
L
A
K
KRGSKG
K
L
E
A
I
I
TPPPAKKAKSPSQKKPVSKKAGGKKGA
R
K
S
K
KKQGEVSKAASADSTTEGTPAD
G
F
T
V
L
S
T
K
S
L
FLG
Q
K
L
N
L
I
H
S
E
I
S
N
LAG
F
E
V
E
A
I
INPTNA
D
I
D
L
K
D
D
L
G
N
T
L
E
K
KG
G
K
E
F
V
E
A
V
L
E
L
R
KKNG
P
L
E
V
AG
A
A
VSAGHGL
P
A
K
F
V
I
H
CNSPVW
G
A
D
---
K
C
E
E
L
L
E
K
T
V
K
N
C
L
A
LADDKKL
K
S
IAFPSIGSGRNGF
P
K
Q
T
A
A
Q
L
I
L
K
A
I
S
S
Y
F
V
S
T
M
SSS
I
K
T
V
Y
F
V
L
FDSES
I
G
I
Y
V
Q
E
M
A
KLDAN
43
Fugue
90.19
100%
-131
- C5 -
-
1ZR5
-
H2AY_HUMAN
A:
[179-367]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
G
F
T
V
L
S
T
K
S
L
F
L
G
Q
K
L
N
L
I
H
S
E
I
S
N
L
A
G
F
E
V
E
A
I
I
N
P
T
N
A
D
I
D
L
K
D
D
L
G
N
T
L
E
K
K
G
G
K
E
F
V
E
A
V
L
E
L
R
K
K
N
G
P
L
E
V
A
G
A
A
V
S
A
G
H
G
L
P
A
K
F
V
I
H
C
N
S
P
V
W
G
A
D
---
K
C
E
E
L
L
E
K
T
V
K
N
C
L
A
L
A
D
D
K
K
L
K
S
I
A
F
P
S
I
G
S
G
R
N
G
F
P
K
Q
T
A
A
Q
L
I
L
K
A
I
S
S
Y
F
V
S
T
M
S
S
S
I
K
T
V
Y
F
V
L
F
D
S
E
S
I
G
I
Y
V
Q
E
M
A
K
L
---
1
PsiBlast_PDB
90.19
100%
-131
- C5 -
-
1ZR5
-
H2AY_HUMAN
A:
[179-367]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
G
F
T
V
L
S
T
K
S
L
F
L
G
Q
K
L
N
L
I
H
S
E
I
S
N
L
A
G
F
E
V
E
A
I
I
N
P
T
N
A
D
I
D
L
K
D
D
L
G
N
T
L
E
K
K
G
G
K
E
F
V
E
A
V
L
E
L
R
K
K
N
G
P
L
E
V
A
G
A
A
V
S
A
G
H
G
L
P
A
K
F
V
I
H
C
N
S
P
V
W
G
A
D
---
K
C
E
E
L
L
E
K
T
V
K
N
C
L
A
L
A
D
D
K
K
L
K
S
I
A
F
P
S
I
G
S
G
R
N
G
F
P
K
Q
T
A
A
Q
L
I
L
K
A
I
S
S
Y
F
V
S
T
M
S
S
S
I
K
T
V
Y
F
V
L
F
D
S
E
S
I
G
I
Y
V
Q
E
M
A
K
L
---
32
HHSearch
89.21
87%
-135
- C5 -
-
5IIT
2
H2AY_HUMAN (first)
C:
[182-369]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
G
F
T
V
L
S
T
K
S
L
F
L
G
Q
K
L
Q
V
V
Q
A
D
I
A
S
---
I
D
S
D
A
V
V
H
P
T
N
T
D
F
Y
I
G
G
E
V
G
N
T
L
E
K
K
G
G
K
E
F
V
E
A
V
L
E
L
R
K
K
N
G
P
L
E
V
A
G
A
A
V
S
A
G
H
G
L
P
A
K
F
V
I
H
C
N
S
P
V
W
G
A
D
---
K
C
E
E
L
L
E
K
T
V
K
N
C
L
A
L
A
D
D
K
K
L
K
S
I
A
F
P
S
I
G
S
G
R
N
G
F
P
K
Q
T
A
A
Q
L
I
L
K
A
I
S
S
Y
F
V
S
T
M
S
S
S
I
K
T
V
Y
F
V
L
F
D
S
E
S
I
G
I
Y
V
Q
E
M
A
K
L
E
H
-
2
PsiBlast_PDB
89.18
87%
-128
- C5 -
-
1ZR3
1
H2AY_HUMAN
A:
[24-209]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
F
T
V
L
S
T
K
S
L
F
L
G
Q
K
L
Q
V
V
Q
A
D
I
A
S
I
---
D
S
D
A
V
V
H
P
T
N
T
D
F
Y
I
G
G
E
V
G
N
T
L
E
K
K
G
G
K
E
F
V
E
A
V
L
E
L
R
K
K
N
G
P
L
E
V
A
G
A
A
V
S
A
G
H
G
L
P
A
K
F
V
I
H
C
N
S
P
V
W
G
A
D
---
K
C
E
E
L
L
E
K
T
V
K
N
C
L
A
L
A
D
D
K
K
L
K
S
I
A
F
P
S
I
G
S
G
R
N
G
F
P
K
Q
T
A
A
Q
L
I
L
K
A
I
S
S
Y
F
V
S
T
M
S
S
S
I
K
T
V
Y
F
V
L
F
D
S
E
S
I
G
I
Y
V
Q
E
M
A
K
L
D
--
3
PsiBlast_PDB
88.68
87%
-133
- C5 -
-
2FXK
-
H2AY_HUMAN
A:
[182-368]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
F
T
V
L
S
T
K
S
L
F
L
G
Q
K
L
Q
V
V
Q
A
D
I
A
S
I
---
D
S
D
A
V
V
H
P
T
N
T
D
F
Y
I
G
G
E
V
G
N
T
L
E
K
K
G
G
K
E
F
V
E
A
V
L
E
L
R
K
K
N
G
P
L
E
V
A
G
A
A
V
S
A
G
H
G
L
P
A
K
F
V
I
H
C
N
S
P
V
W
G
A
D
---
K
C
E
E
L
L
E
K
T
V
K
N
C
L
A
L
A
D
D
K
K
L
K
S
I
A
F
P
S
I
G
S
G
R
N
G
F
P
K
Q
T
A
A
Q
L
I
L
K
A
I
S
S
Y
F
V
S
T
M
S
S
S
I
K
T
V
Y
F
V
L
F
D
S
E
S
I
G
I
Y
V
Q
E
M
A
K
L
D
A
-
33
HHSearch
88.00
87%
-130
- C5 -
-
5LNC
-
H2AY_HUMAN
B:
[182-369]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
G
F
T
V
L
S
T
K
S
L
F
L
G
Q
K
L
Q
V
V
Q
A
D
I
A
S
---
I
D
S
D
A
V
V
H
P
T
N
T
D
F
Y
I
G
G
E
V
G
N
T
L
E
K
K
G
G
K
E
F
V
E
A
V
L
E
L
R
K
K
N
G
P
L
E
V
A
G
A
A
V
S
A
G
H
G
L
P
A
K
F
V
I
H
C
N
S
P
V
W
G
A
D
---
K
C
E
E
L
L
E
K
T
V
K
N
C
L
A
L
A
D
D
K
K
L
K
S
I
A
F
P
S
I
G
S
G
R
N
G
F
P
K
Q
T
A
A
Q
L
I
L
K
A
I
S
S
Y
F
V
S
T
M
S
S
S
I
K
T
V
Y
F
V
L
F
D
S
E
S
I
G
I
Y
V
Q
E
M
A
K
L
E
H
-
31
HHSearch
87.79
84%
-127
- C5 -
-
1YD9
-
H2AY_RAT
A:
[6-193]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
F
T
V
L
S
T
K
S
L
F
L
G
Q
K
L
Q
V
V
Q
A
D
I
A
S
---
I
D
S
D
A
V
V
H
P
T
N
T
D
F
Y
I
G
G
E
V
G
S
T
L
E
K
K
G
G
K
E
F
V
E
A
V
L
E
L
R
K
K
N
G
P
L
E
V
A
G
A
A
V
S
A
G
H
G
L
P
A
K
F
V
I
H
C
N
S
P
V
W
G
S
D
---
K
C
E
E
L
L
E
K
T
V
K
N
C
L
A
L
A
D
D
R
K
L
K
S
I
A
F
P
S
I
G
S
G
R
N
G
F
P
K
Q
T
A
A
Q
L
I
L
K
A
I
S
S
Y
F
V
S
T
M
S
S
S
I
K
T
V
Y
F
V
L
F
D
S
E
S
I
G
I
Y
V
Q
E
M
A
K
L
D
A
N
6
PsiBlast_PDB
87.50
83%
-127
- C5 -
-
1YD9
-
H2AY_RAT
A:
[6-193]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
F
T
V
L
S
T
K
S
L
F
L
G
Q
K
L
Q
V
V
Q
A
D
I
A
S
I
---
D
S
D
A
V
V
H
P
T
N
T
D
F
Y
I
G
G
E
V
G
S
T
L
E
K
K
G
G
K
E
F
V
E
A
V
L
E
L
R
K
K
N
G
P
L
E
V
A
G
A
A
V
S
A
G
H
G
L
P
A
K
F
V
I
H
C
N
S
P
V
W
G
S
D
---
K
C
E
E
L
L
E
K
T
V
K
N
C
L
A
L
A
D
D
R
K
L
K
S
I
A
F
P
S
I
G
S
G
R
N
G
F
P
K
Q
T
A
A
Q
L
I
L
K
A
I
S
S
Y
F
V
S
T
M
S
S
S
I
K
T
V
Y
F
V
L
F
D
S
E
S
I
G
I
Y
V
Q
E
M
A
K
L
D
A
N
5
PsiBlast_PDB
86.19
87%
-129
- C5 -
-
3IIF
1
H2AY_HUMAN
A:
[23-205]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
G
F
T
V
L
S
T
K
S
L
F
L
G
Q
K
L
Q
V
V
Q
A
D
I
A
S
I
---
D
S
D
A
V
V
H
P
T
N
T
D
F
Y
I
G
G
E
V
G
N
T
L
E
K
K
G
G
K
E
F
V
E
A
V
L
E
L
R
K
K
N
G
P
L
E
V
A
G
A
A
V
S
A
G
H
G
L
P
A
K
F
V
I
H
C
N
S
P
V
W
G
A
D
---
K
C
E
E
L
L
E
K
T
V
K
N
C
L
A
L
A
D
D
K
K
L
K
S
I
A
F
P
S
I
G
S
G
R
N
G
F
P
K
Q
T
A
A
Q
L
I
L
K
A
I
S
S
Y
F
V
S
T
M
S
S
S
I
K
T
V
Y
F
V
L
F
D
S
E
S
I
G
I
Y
V
Q
E
M
------
4
PsiBlast_PDB
86.05
87%
-126
- C5 -
-
3IID
1
H2AY_HUMAN
A:
[22-206]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
D
G
F
T
V
L
S
T
K
S
L
F
L
G
Q
K
L
Q
V
V
Q
A
D
I
A
S
I
---
D
S
D
A
V
V
H
P
T
N
T
D
F
Y
I
G
G
E
V
G
N
T
L
E
K
K
G
G
K
E
F
V
E
A
V
L
E
L
R
K
K
N
G
P
L
E
V
A
G
A
A
V
S
A
G
H
G
L
P
A
K
F
V
I
H
C
N
S
P
V
W
G
A
D
---
K
C
E
E
L
L
E
K
T
V
K
N
C
L
A
L
A
D
D
K
K
L
K
S
I
A
F
P
S
I
G
S
G
R
N
G
F
P
K
Q
T
A
A
Q
L
I
L
K
A
I
S
S
Y
F
V
S
T
M
S
S
S
I
K
T
V
Y
F
V
L
F
D
S
E
S
I
G
I
Y
V
Q
E
M
A
-----
30
HHSearch
85.56
84%
-127
- C5 -
-
1YD9
-
H2AY_RAT
C:
[5-191]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
G
F
T
V
L
S
T
K
S
L
F
L
G
Q
K
L
Q
V
V
Q
A
D
I
A
S
---
I
D
S
D
A
V
V
H
P
T
N
T
D
F
Y
I
G
G
E
V
G
S
T
L
E
K
K
G
G
K
E
F
V
E
A
V
L
E
L
R
K
K
N
G
P
L
E
V
A
G
A
A
V
S
A
G
H
G
L
P
A
K
F
V
I
H
C
N
S
P
V
W
G
S
D
---
K
C
E
E
L
L
E
K
T
V
K
N
C
L
A
L
A
D
D
R
K
L
K
S
I
A
F
P
S
I
G
S
G
R
N
G
F
P
K
Q
T
A
A
Q
L
I
L
K
A
I
S
S
Y
F
V
S
T
M
S
S
S
I
K
T
V
Y
F
V
L
F
D
S
E
S
I
G
I
Y
V
Q
E
M
A
K
L
D
--
34
HHSearch
62.95
20%
-159
- C5 -
-
5FSZ
-
?
A:
[91-258]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
L
R
H
I
A
L
Y
N
G
P
V
T
D
---
L
Q
L
D
A
I
V
N
A
A
N
K
T
C
L
G
G
K
G
V
D
G
A
I
H
A
A
A
G
P
L
L
V
R
E
C
A
T
F
----
K
G
C
D
T
G
Q
C
R
L
T
K
G
Y
N
L
P
A
R
Y
V
L
H
T
V
G
P
I
G
E
R
------
P
E
E
L
R
S
C
Y
R
S
I
L
S
L
A
H
R
N
R
L
R
S
I
G
F
C
C
V
S
T
G
V
Y
G
Y
P
L
I
P
A
T
R
I
A
V
D
E
T
I
E
Y
L
K
Q
H
F
-
S
A
F
D
L
C
C
F
A
C
F
K
L
E
E
Y
N
A
Y
T
D
C
L
R
A
W
L
--
27
HHSearch
61.17
19%
-156
- C5 -
-
5FSV
2
?
A:
[99-262]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
L
R
H
I
A
L
Y
R
G
P
V
T
D
---
L
Q
L
D
A
I
V
N
A
A
N
T
R
C
L
G
G
G
G
V
D
G
A
I
H
R
V
A
G
P
L
L
L
R
E
C
A
T
F
----
N
G
C
Q
T
G
E
C
R
L
T
K
G
Y
Q
L
P
A
R
Y
V
L
H
T
V
G
P
V
G
E
------
R
P
D
M
L
R
K
C
Y
R
S
I
L
S
L
A
L
K
N
G
L
R
S
I
G
F
C
C
V
S
T
G
V
Y
G
Y
P
L
L
P
A
T
R
I
A
L
G
E
T
R
K
F
L
E
E
H
-
G
G
A
L
D
M
C
C
F
A
C
F
Q
E
D
E
Y
K
T
Y
E
K
C
V
G
-----
35
HHSearch
60.88
25%
-70
- C5 -
-
5CB5
-
YMDB_ECOLI
E:
[9-180]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
R
I
H
V
V
Q
G
D
I
T
K
---
L
A
V
D
V
I
V
N
A
A
A
P
S
L
M
G
G
G
G
V
A
G
A
I
H
R
A
A
G
P
A
L
L
D
A
C
L
K
V
R
Q
Q
Q
G
D
C
P
T
G
H
A
V
I
T
L
A
G
D
L
P
A
K
A
V
V
H
T
V
G
P
V
W
R
G
G
EQ-
N
E
D
Q
L
L
Q
D
A
Y
L
N
S
L
R
L
V
A
A
N
S
Y
T
S
V
A
F
P
A
I
S
T
G
V
Y
G
Y
P
R
A
A
A
A
E
I
A
V
K
T
V
S
E
F
I
T
R
H
A
--
L
P
E
Q
V
Y
F
V
C
Y
D
E
E
N
A
H
L
Y
E
R
L
L
T
Q
Q
---
29
HHSearch
60.08
27%
-70
- C5 -
-
3Q6Z
1
A:
[27-213]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
C
F
S
R
T
V
L
A
P
G
V
V
L
I
V
Q
Q
G
D
L
A
R
---
L
P
V
D
V
V
V
N
A
S
N
E
D
L
K
H
Y
G
G
L
A
A
A
L
S
K
A
A
G
P
E
L
Q
A
D
C
D
Q
I
V
K
R
E
G
R
L
L
P
G
N
A
T
I
S
K
A
G
K
L
P
Y
H
H
V
I
H
A
V
G
P
R
W
S
G
Y
E
A
P
R
C
V
Y
L
L
R
R
A
V
Q
L
S
L
C
L
A
E
K
Y
K
Y
R
S
I
A
I
P
A
I
S
S
G
V
F
G
F
P
L
G
R
C
V
E
T
I
V
S
A
I
K
E
N
F
Q
F
K
K
-
H
C
L
K
E
I
Y
L
V
D
V
S
E
K
T
V
E
A
F
A
E
A
V
K
T
V
F
--
37
HHSearch
59.04
26%
-57
- C5 -
-
5CB3
1
YMDB_ECOLI
A:
[9-179]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
R
I
H
V
V
Q
G
D
I
T
K
---
L
A
V
D
V
I
V
N
A
A
N
P
S
L
M
G
G
G
G
V
D
G
A
I
H
R
A
A
G
P
A
L
L
D
A
C
L
K
V
R
Q
Q
Q
G
D
C
P
T
G
H
A
V
I
T
L
A
G
D
L
P
A
K
A
V
V
H
T
V
G
P
V
W
R
G
G
EQ-
N
E
D
Q
L
L
Q
D
A
Y
L
N
S
L
R
L
V
A
A
N
S
Y
T
S
V
A
F
P
A
I
S
T
G
V
Y
G
Y
P
R
A
A
A
A
E
I
A
V
K
T
V
S
E
F
I
T
R
H
--
A
L
P
E
Q
V
Y
F
V
C
Y
D
E
E
N
A
H
L
Y
E
R
L
L
T
Q
----
28
HHSearch
58.96
99%
-160
- C6 -
-
2F8N
-
G:
[1012-1119]
---------
S
T
K
T
S
R
S
A
K
A
G
V
I
F
P
V
G
R
M
L
R
Y
I
K
K
G
H
P
K
Y
R
I
G
V
G
A
P
V
Y
M
A
A
V
L
E
Y
L
T
A
E
I
L
E
L
A
V
N
A
A
R
D
N
K
K
G
R
V
T
P
R
H
I
L
L
A
V
A
N
D
E
E
L
N
Q
L
L
K
G
V
T
I
A
S
G
G
V
L
P
N
I
H
P
E
L
L
A
K
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
58.96
99%
-160
- C6 -
-
2F8N
-
G:
[1012-1119]
---------
S
T
K
T
S
R
S
A
K
A
G
V
I
F
P
V
G
R
M
L
R
Y
I
K
K
G
H
P
K
Y
R
I
G
V
G
A
P
V
Y
M
A
A
V
L
E
Y
L
T
A
E
I
L
E
L
A
V
N
A
A
R
D
N
K
K
G
R
V
T
P
R
H
I
L
L
A
V
A
N
D
E
E
L
N
Q
L
L
K
G
V
T
I
A
S
G
G
V
L
P
N
I
H
P
E
L
L
A
K
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
58.71
68%
-
- C5 -
-
2XD7
-
H2AW_HUMAN
A:
[179-369]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
G
D
G
F
T
I
L
S
S
K
S
L
V
L
G
Q
K
L
S
L
T
Q
S
D
I
S
H
I
G
S
M
R
V
E
G
I
V
H
P
T
T
A
E
I
D
L
K
E
D
I
G
K
A
L
E
K
A
G
G
K
E
F
L
E
T
V
K
E
L
R
K
S
Q
G
P
L
E
V
A
E
A
A
V
S
Q
S
S
G
L
A
A
K
F
V
I
H
C
H
I
P
Q
W
G
S
D
---
K
C
E
E
Q
L
E
E
T
I
K
N
C
L
S
A
A
E
D
K
K
L
K
S
V
A
F
P
P
F
P
S
G
R
N
C
F
P
K
Q
T
A
A
Q
V
T
L
K
A
I
S
A
H
F
D
D
S
S
A
S
S
L
K
N
V
Y
F
L
L
F
D
S
E
S
I
G
I
Y
V
Q
E
M
A
K
L
---
24
HHSearch
58.25
24%
-68
- C5 -
-
2X47
-
MACD1_HUMAN
A:
[58-233]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
Q
L
N
E
K
I
S
L
L
R
S
D
I
T
K
---
L
E
V
D
A
I
V
N
A
A
N
S
S
L
L
G
G
G
G
V
D
G
C
I
H
R
A
A
G
P
L
L
T
D
E
C
R
T
L
----
Q
S
C
K
T
G
K
A
K
I
T
G
G
Y
R
L
P
A
K
Y
V
I
H
T
V
G
P
I
A
Y
G
E
PS
A
S
Q
A
A
E
L
R
S
C
Y
L
S
S
L
D
L
L
L
E
H
R
L
R
S
V
A
F
P
C
I
S
T
G
V
F
G
Y
P
C
E
A
A
A
E
I
V
L
A
T
L
R
E
W
L
E
Q
H
K
-
D
K
V
D
R
L
I
I
C
V
F
L
E
K
D
E
D
I
Y
R
S
R
L
P
H
Y
F
P
-