@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : K1C18_HUMAN: (2018-10-04 )
MSFTTRSTFSTNYRSLGSVQAPSYGARPVSSAASVYAGAGGSGSRISVSRSTSFRGGMGSGGLATGIAGGLAGMGGIQNEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKGPQVRDWSHYFKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVENDIHGLRKVIDDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAPKSQDLAKIMADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELRRTVQSLEIDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQEYEALLNIKVKLEAEIATYRRLLEDGEDFNLGDALDSSNSMQTIQKTTTRRIVDGKVVSETNDTKVLRH
Atome Classification :
(20 SA)
-.........10........20.......-----.30........40........------50........60..--......70.......--.80.......----------.90........100.......110...--....120.......130.......140...--....150.......160.......170.---......180.......190.....----..200.......210.......220.......230.....---..240.......250..-----.....260.......270.......280.......290.......300.......310.......320....--...330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430--
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
-MSFTTRSTFST
N
Y
RSLGSVQAPSYGARP-----VSSAA
S
V
Y
AGAGGSG
S
R
I
S
V
S------RSTSFRGGMGSG
G
L
--
A
T
G
I
A
G
G
L
AGMGGIQ--
N
E
K
E
T
M
Q
S
L
N
----------
D
R
L
A
S
Y
L
D
R
V
R
S
LETE
N
R
R
L
E
S
K
I
R
E
H
--
L
E
KKGPQVR
D
W
S
H
Y
F
K
I
I
E
D
L
R
A
Q
I
F
ANTV--DN
A
R
I
V
L
Q
IDNARLAAD
D
F
R
V
K
Y
E
T
E
L
A
---
M
R
Q
S
V
E
N
D
I
H
G
L
R
K
V
IDDTN
I
T
R
L
----
Q
L
E
T
E
I
E
A
L
K
E
E
L
L
F
M
KKN
H
E
E
E
V
K
G
L
Q
A
Q
IASSG
L
T
V
E
V---DAPK
S
Q
D
L
A
K
I
M
A
D
I
R
A
-----
Q
Y
D
E
L
A
R
K
N
R
E
E
L
D
K
Y
W
S
Q
Q
IEES
T
T
V
V
T
TQSAEVGA
A
E
T
T
L
T
E
L
R
R
T
V
Q
S
L
E
I
D
L
D
S
M
R
N
L
K
A
S
L
E
N
S
L
R
E
--
V
E
A
R
Y
A
L
Q
M
E
QL
N
G
I
L
L
H
L
E
S
E
L
A
Q
T
R
A
E
G
Q
R
Q
A
Q
E
Y
E
A
L
L
N
I
K
V
K
L
E
A
E
I
A
T
Y
R
R
L
LEDGEDFNLGDALDSSNS
M
Q
T
I
Q
K
T
T
TRRIVD
G
K
V
VSETNDTKVLRH----
2
PsiBlast_PDB
70.42
43%
-39
- C1 -
-
4ZRY
-
A:
[15-122]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
T
T
E
I
D
N
N
I
E
Q
I
S
S
Y
K
S
E
I
T
E
L
R
R
N
V
Q
A
L
E
I
E
L
Q
S
Q
L
A
L
K
Q
S
L
E
A
S
L
A
E
--
T
E
G
R
Y
C
V
Q
L
S
Q
I
Q
A
Q
I
S
A
L
E
E
Q
L
Q
Q
I
R
A
E
T
E
C
Q
N
T
E
Y
Q
Q
L
L
D
I
K
I
R
L
E
N
E
I
Q
T
Y
R
S
L
L
E
-------------------------------------------------
63
Fugue
69.93
15%
62
- C2 -
-
5IAU
2
?
A:
[9-469]
C
T
S
I
L
V
G
K
K
A
S
I
D
G
S
T
L
I
S
R
N
D
D
G
H
E
A
L
D
P
Q
R
F
V
V
V
N
P
E
D
Q
P
R
D
Y
T
S
V
I
S
K
V
N
V
K
L
P
DDP
Q
R
Y
T
S
I
P
N
S
I
L
T
N
G
I
WP
A
A
G
I
N
S
S
N
V
A
M
S
A
T
E
T
I
T
T
N
S
R
V
Q
G
L
D
PFVENGLGEE
D
L
V
T
V
V
L
P
Y
V
K
S
A
R
E
G
V
K
R
L
G
S
L
L
E
E
Y
GT
Y
E
P
N
G
I
S
F
A
D
-
N
E
E
V
W
W
L
E
T
I
G
G
H
H
W
A
A
V
R
IP
D
D
A
Y
V
V
A
---
P
N
R
M
N
I
D
Q
F
D
F
D
S
D
D
T
L
C
SSD
L
K
D
L
I
D
N
--
N
N
L
N
P
D
F
E
N
Y
N
L
R
H
I
FGSA
S
I
K
D
T
V
Y
N
N
P
R
T
W
Y
G
Q
K
F
F
S
P
D
D
T
A
D
D
P
M
E
---
Q
D
L
P
F
I
C
---
H
A
N
R
K
I
S
V
E
D
V
K
F
V
L
S
S
HFENT
K
Y
D
V
Y
G
S
G
S
Q
S
D
K
T
L
F
R
P
I
G
I
N
R
N
H
N
V
H
I
L
Q
I
R
--
N
N
V
P
T
E
I
A
G
I
H
W
L
A
Y
G
-
A
N
T
F
N
T
V
V
P
F
Y
A
N
V
N
D
T
--
P
--
V
Q
Y
K
N
A
T
G
K
F
D
L
N
N
-
M
Y
W
L
S
C
T
T
A
L
L
G
D
T
D
Y
D
F
Y
V
D
M
R
N
D
Y
E
L
D
A
M
S
A
Y
R
K
I
Q
N
D
T
D
A
D
I
S
G
Q
K
D
I
E
K
Y
L
E
N
A
N
K
K
L
A
D
V
A
F
E
K
Q
N
K
L
L
G
D
M
V
T
T
G
S
N
N
M
K
L
R
Y
NLND
24
HHSearch
67.39
44%
-38
- C1 -
-
4ZRY
-
A:
[15-124]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
T
T
E
I
D
N
N
I
E
Q
I
S
S
Y
K
S
E
I
T
E
L
R
R
N
V
Q
A
L
E
I
E
L
Q
S
Q
L
A
L
K
Q
S
L
E
A
S
L
A
E
--
T
E
G
R
Y
C
V
Q
L
S
Q
I
Q
A
Q
I
S
A
L
E
E
Q
L
Q
Q
I
R
A
E
T
E
C
Q
N
T
E
Y
Q
Q
L
L
D
I
K
I
R
L
E
N
E
I
Q
T
Y
R
S
L
L
E
-
G
E
----------------------------------------------
1
PsiBlast_PDB
67.02
46%
-
- C1 -
-
3TNU
-
K1C14_HUMAN
A:
[332-420]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
E
L
R
R
T
M
Q
N
L
E
I
E
L
Q
S
Q
L
S
M
K
A
S
L
E
N
S
L
E
E
--
T
K
G
R
Y
C
M
Q
L
A
Q
I
Q
E
M
I
G
S
V
E
E
Q
L
A
Q
L
R
C
E
M
E
Q
Q
N
Q
E
Y
K
I
L
L
D
V
K
T
R
L
E
Q
E
I
A
T
Y
R
R
L
L
E
-------------------------------------------------
21
HHSearch
66.70
48%
-
- C1 -
-
3TNU
-
K1C14_HUMAN
A:
[332-421]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
E
L
R
R
T
M
Q
N
L
E
I
E
L
Q
S
Q
L
S
M
K
A
S
L
E
N
S
L
E
E
--
T
K
G
R
Y
C
M
Q
L
A
Q
I
Q
E
M
I
G
S
V
E
E
Q
L
A
Q
L
R
C
E
M
E
Q
Q
N
Q
E
Y
K
I
L
L
D
V
K
T
R
L
E
Q
E
I
A
T
Y
R
R
L
L
E
-
G
-----------------------------------------------
32
HHSearch
62.43
39%
50
- C1 -
-
1X8Y
-
LMNA_HUMAN
A:
[313-386]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
A
K
E
A
K
L
R
D
--
L
E
D
S
L
A
R
E
R
D
T
S
R
R
L
L
A
E
K
E
R
E
M
A
E
M
R
A
R
M
Q
Q
Q
L
D
E
Y
Q
E
L
L
D
I
K
L
A
L
D
M
E
I
H
A
Y
R
K
L
L
E
-
G
E
E
E
R
-------------------------------------------
23
HHSearch
62.29
30%
-70
- C1 -
-
4ZRY
-
B:
[17-120]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
H
G
D
S
V
R
N
S
K
I
E
I
S
E
L
N
R
V
I
Q
R
L
R
S
E
I
D
N
V
K
K
Q
I
S
N
L
Q
Q
S
I
S
D
--
A
E
Q
R
G
E
N
A
L
K
D
A
K
N
K
L
N
D
L
E
D
A
L
Q
Q
A
K
E
D
L
A
R
L
L
R
D
Y
Q
E
L
M
N
T
K
L
A
L
D
L
E
I
A
T
Y
R
T
L
L
E
-
G
E
----------------------------------------------
51
Fugue
62.02
29%
-70
- C1 -
-
4ZRY
-
B:
[17-120]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
H
G
D
S
V
R
N
S
K
I
E
I
S
E
L
N
R
V
I
Q
R
L
R
S
E
I
D
N
V
K
K
Q
I
S
N
L
Q
Q
S
I
S
D
--
A
E
Q
R
G
E
N
A
L
K
D
A
K
N
K
L
N
D
L
E
D
A
L
Q
Q
A
K
E
D
L
A
R
L
L
R
D
Y
Q
E
L
M
N
T
K
L
A
L
D
L
E
I
A
T
Y
R
T
L
L
E
G
E
-----------------------------------------------
12
PsiBlast_PDB
61.90
41%
94
- C1 -
-
1X8Y
-
LMNA_HUMAN
A:
[314-386]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
A
K
E
A
K
L
R
D
--
L
E
D
S
L
A
R
E
R
D
T
S
R
R
L
L
A
E
K
E
R
E
M
A
E
M
R
A
R
M
Q
Q
Q
L
D
E
Y
Q
E
L
L
D
I
K
L
A
L
D
M
E
I
H
A
Y
R
K
L
L
E
-
G
E
E
E
R
-------------------------------------------
35
HHSearch
61.41
36%
-123
- C1 -
-
1GK4
-
VIME_HUMAN
B:
[2-79]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
V
D
A
L
K
G
T
N
E
S
L
E
R
Q
M
R
E
--
M
E
E
N
F
A
V
E
A
A
N
Y
Q
D
T
I
G
R
L
Q
D
E
I
Q
N
M
K
E
E
M
A
R
H
L
R
E
Y
Q
D
L
L
N
V
K
M
A
L
D
I
E
I
A
T
Y
R
K
L
L
E
-
G
-----------------------------------------------
17
PsiBlast_PDB
60.31
26%
-251
- C1 -
-
3TRT
-
VIME_HUMAN
A:
[6-76]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
C
T
A
A
M
R
D
V
R
Q
-----
Q
Y
E
S
V
A
A
K
N
L
Q
E
A
E
E
W
Y
K
S
K
F
A
D
L
S
E
A
A
N
R
N
N
D
A
L
R
Q
A
K
Q
E
S
T
E
Y
R
R
Q
V
Q
S
L
T
M
E
V
D
A
L
K
--------------------------------------------------------------------------------------------------------------------------
59
Fugue
60.01
17%
-11
* C3 *
-
4BLP
-
?
A:
[32-303]
-----------------------------------------------------------------------------------------------------------------------------------------------
P
K
V
A
A
P
A
V
V
E
G
S
S
T
N
A
A
A
V
K
K
S
L
R
D
G
G
M
T
A
--
L
P
S
E
I
L
F
A
V
G
S
I
P
L
V
V
D
K
D
A
L
S
T
L
A
A
A
L
---
V
A
S
D
P
S
T
W
F
V
A
N
R
E
L
I
R
A
V
V
F
V
P
Q
----
Q
--
N
N
V
L
R
A
T
P
L
L
S
V
R
P
V
A
S
L
S
S
V
H
N
W
Q
V
R
N
H
L
S
G
L
H
V
V
V
G
G
T
G
A
G
K
S
K
W
L
N
A
Q
T
P
D
V
T
I
-----
R
W
G
E
----
P
G
E
T
F
D
M
-------
E
E
S
S
I
A
V
A
D
L
T
E
M
L
A
V
A
L
L
L
A
T
A
D
Y
R
-----
V
V
I
D
S
F
R
N
L
V
F
G
I
T
G
A
A
G
P
GG
V
S
V
A
L
Y
A
A
L
T
S
L
N
N
I
C
A
E
L
G
V
L
L
V
A
A
I
N
P
M
S
S
D
D
K
V
S
L
V
Y
N
N
I
A
A
S
V
-
A
G
M
T
V
V
N
N
A
A
V
V
S
Q
T
I
R
S
G
T
G
R
I
F
S
G
----------------------------------
31
HHSearch
59.22
37%
-
- C1 -
-
3UF1
-
VIME_HUMAN
D:
[146-248]
--------------------------------------------------------------------------------------------------------------------------------------------------------
L
G
D
L
Y
E
E
E
M
R
E
L
R
R
Q
V
D
Q
L
T
N
--
D
K
A
R
V
E
V
E
R
D
N
L
A
E
D
I
M
R
L
R
E
K
L
Q
E
E
M
L
---
Q
R
E
E
A
E
N
T
L
Q
S
F
R
Q
D
V
D
N
A
S
L
A
R
L
----
D
L
E
R
K
V
E
S
L
Q
E
E
I
A
F
L
K
K
L
H
E
E
E
I
Q
E
L
Q
A
Q
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
58.75
35%
57
- C1 -
-
1GK4
-
VIME_HUMAN
A:
[1-78]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
C
E
V
D
A
L
K
G
T
N
E
S
L
E
R
Q
M
R
E
--
M
E
E
N
F
A
V
E
A
A
N
Y
Q
D
T
I
G
R
L
Q
D
E
I
Q
N
M
K
E
E
M
A
R
H
L
R
E
Y
Q
D
L
L
N
V
K
M
A
L
D
I
E
I
A
T
Y
R
K
L
L
E
-------------------------------------------------
41
HHSearch
58.25
41%
90
- C1 -
-
3V5B
-
LMNA_HUMAN
A:
[316-385]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
E
A
K
L
R
D
--
L
E
D
S
L
A
R
E
R
D
T
S
R
R
L
L
A
E
K
E
R
E
M
A
E
M
R
A
R
M
Q
Q
Q
L
D
E
Y
Q
E
L
L
D
I
K
L
A
L
D
M
E
I
H
A
Y
R
K
L
L
E
-
G
E
E
E
--------------------------------------------
50
Fugue
57.81
39%
50
- C1 -
-
1X8Y
-
LMNA_HUMAN
A:
[313-386]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
A
K
E
A
K
L
R
D
--
L
E
D
S
L
A
R
E
R
D
T
S
R
R
L
L
A
E
K
E
R
E
M
A
E
M
R
A
R
M
Q
Q
Q
L
D
E
Y
Q
E
L
L
D
I
K
L
A
L
D
M
E
I
H
A
Y
R
K
L
L
E
G
E
E
E
R
--------------------------------------------
42
HHSearch
56.93
41%
100
- C1 -
-
3V4Q
-
LMNA_HUMAN
A:
[316-385]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
E
A
K
L
R
D
--
L
E
D
S
L
A
R
E
R
D
T
S
W
R
L
L
A
E
K
E
R
E
M
A
E
M
R
A
R
M
Q
Q
Q
L
D
E
Y
Q
E
L
L
D
I
K
L
A
L
D
M
E
I
H
A
Y
R
K
L
L
E
-
G
E
E
E
--------------------------------------------
29
HHSearch
55.74
32%
-12
- C1 -
-
3S4R
-
B:
[4-91]
------------------------------------------------------------------------------------------
R
T
--
N
E
K
V
E
L
Q
E
L
N
----------
D
R
F
A
N
L
I
D
K
V
R
F
L
E
Q
Q
N
K
I
L
L
A
E
L
E
Q
L
--
K
G
Q
G
--
K
S
R
L
G
D
L
Y
E
E
E
M
R
E
L
R
R
Q
V
D
Q
L
T
N
--
D
K
A
R
V
E
V
E
R
D
N
L
A
E
D
I
M
R
L
R
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
47
HHSearch
55.67
34%
-13
- C1 -
-
4YV3
-
VIME_HUMAN
A:
[3-76]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
L
T
N
--
D
K
A
R
V
E
V
E
R
D
N
L
A
E
D
I
M
R
L
R
E
K
L
Q
E
E
M
L
---
Q
R
E
E
A
E
N
T
L
Q
S
F
R
Q
D
V
D
N
A
S
L
A
R
L
----
D
L
E
R
K
V
E
S
L
Q
E
E
I
A
F
L
K
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
55.62
40%
134
- C1 -
-
3V4Q
-
LMNA_HUMAN
A:
[314-385]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
A
K
E
A
K
L
R
D
--
L
E
D
S
L
A
R
E
R
D
T
S
W
R
L
L
A
E
K
E
R
E
M
A
E
M
R
A
R
M
Q
Q
Q
L
D
E
Y
Q
E
L
L
D
I
K
L
A
L
D
M
E
I
H
A
Y
R
K
L
L
E
G
E
E
E
---------------------------------------------