@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : LCP2_MOUSE: (2018-07-13 )
MALKNVPFRSEVLAWNSDNLADYFRKLNYRDCEKAVKKYHIDGARFLNLTENDIQKFPKLRMPLLSKLSQDINKNEERRSIFTRKPQIPRFLEETESHEEDDGGWSSFEDDYESPNDDDPDGEDDGDYESPNEEEQALVDDAADYEPPPSNNEEALQSSILPPNSFHNTNSMYIDRPPTGKVSQQPPVPPLRPKPALPPLPTGRNHSPLSPPHPNHEEPSRSGNNKTAKLPAPSIDRSTKPPLDRSLAPLDREPFILGKKPPFSDKPSAPLGREHLPKIQKPPLPPAMDRHERNERLGPVTTRKPPVPRHGRGPDRRENDEDDVHQRPLPQPSLPSMSSNTFPSRSVQPSSKNTFPLAHMPGAFSESNIGFQQSASLPPYFSQGPGNRPPLRSEGRNLPLPVPNRPQPPSPGEEETPLDEEWYVSYITRPEAEAALRKINQDGTFLVRDSSKKTANNPYVLMVLYKDKVYNIQIRYQEESQVYLLGTGLRGKEDFLSVSDIIDYFRKMPLLLIDGKNRGSRYQCTLTHAAGCL
Atome Classification :
(20 SA)
-------.........10.....-...20........30........40........50........60........70........80........90........100.......110.......120.......130........-140.......150.......160.......170.......180....-...190.......200......-.210.......220.......230..-.....240-.......250.......260.......270.......280---.....---...290.......300.......310.......320...-------....330.......340.......350.......360.......370.......380.......390.--......400.......410.......420.......430.......--440.......450........460.......470.......480.......490.....--..500.......510.....-..520.......-530.-
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
-------MALKNVPF
R
S
E
VLAWN-SD
N
L
A
D
Y
F
R
KL
N
Y
R
D
C
E
K
A
V
K
K
YHIDG
A
R
F
L
NL
T
E
N
D
I
Q
KFPKL
R
M
P
L
L
S
K
L
S
Q
D
IN
K
N
E
E
R
R
S
I
FTRKPQI
P
R
F
L
E
E
TESHEEDDGGWSSFEDDYESPNDDDPDGEDDGDYESP-
N
E
E
E
Q
A
L
V-DDAADYEPPPSN
N
E
E
A
L
Q
S
SILPPNSFHNTN
S
M
Y
I
DRPPTGKVSQQP-PVPPLRPKPALPPLPTGRNHSP-LSPPHPNHEEPSRSGNNKTAKLPAPS-IDRSTKPP-LDRSLAPLDREPFILGKKPPFSDKPSAPL
G
R
E
HLPKIQK----PPLPP---A
M
D
R
H
E
R
NERLGPVTTRKPPVPRHGRGPDRRENDEDDVH-------QRPLPQPSLPSMSSNTFPSRSVQPSSKNTFPLAHMPGAFSESNIGFQQSASLPPYFSQGPGNRPPLRS--EGRNLPLPVPNRPQPPSPGEEETPL
D
E
E
W
Y
V
S
Y
ITRP
E
A
E
A
A
L
R
K
I--NQDG
T
F
L
V
RDS-SKKTANN
P
Y
V
L
M
V
L
YKD
K
V
Y
N
I
Q
I
R
Y
QEE
S
Q
V
Y
L
L
GTGLRG
K
E
D
FL
S
--
V
S
D
I
I
D
Y
F
R
KM
P
L
L
L
I
DGKN-RG
S
R
Y
Q
C
T
LTHA-AGCL-
3
PsiBlast_PDB
69.02
29%
-143
- C1 -
-
3GQI
-
?
B:
[72-202]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
G
T
P
K
F
F
L
T
D
N
L
V
F
D
S
L
Y
D
L
I
T
H
Y
Q
Q
-----
V
P
L
R
C
--
N
E
F
E
M
R
L
---
S
E
P
V
P
Q
T
N
A
H
E
----
S
K
E
W
Y
H
A
S
L
T
R
A
Q
A
E
H
M
L
M
R
V
--
P
R
D
G
A
F
L
V
R
----
K
R
N
E
P
N
S
Y
A
I
S
F
R
A
E
G
K
I
K
H
C
R
V
--
Q
Q
E
G
Q
T
V
M
L
G
N
S
-----
E
F
D
S
--
L
V
D
L
I
S
Y
Y
E
K
H
P
L
--------------------------
4
PsiBlast_PDB
66.95
29%
-145
- C1 -
-
4EY0
-
PLCG1_HUMAN
A:
[616-754]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
G
T
P
K
F
F
L
T
D
N
L
V
F
D
S
L
Y
D
L
I
T
H
Y
Q
Q
-----
V
P
L
R
C
--
N
E
F
E
M
R
L
---
S
E
P
V
P
Q
T
N
A
H
E
----
S
K
E
W
Y
H
A
S
L
T
R
A
Q
A
E
H
M
L
M
R
V
--
P
R
D
G
A
F
L
V
R
----
K
R
N
E
P
N
S
Y
A
I
S
F
R
A
E
G
K
I
K
H
C
R
V
--
Q
Q
E
G
Q
T
V
M
L
G
N
S
-----
E
F
D
S
--
L
V
D
L
I
S
Y
Y
E
K
H
P
L
--------------------------
2
PsiBlast_PDB
66.66
39%
-144
- C1 -
-
2EO6
-
A:
[16-120]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
E
A
E
L
L
G
K
P
W
Y
A
G
A
C
D
R
K
S
A
E
E
A
L
H
R
S
--
N
K
D
G
S
F
L
I
R
K
S
-
S
G
H
D
S
K
Q
P
Y
T
L
V
A
F
F
N
K
R
V
Y
N
I
P
V
R
F
I
E
A
T
K
Q
Y
A
L
G
K
K
K
N
G
E
E
Y
F
G
S
--
V
V
E
I
V
N
S
H
Q
H
N
P
L
V
L
I
D
S
Q
N
-------------------
32
HHSearch
66.10
39%
-142
- C1 -
-
2EO6
-
A:
[15-120]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
Q
E
A
E
L
L
G
K
P
W
Y
A
G
A
C
D
R
K
S
A
E
E
A
L
H
R
S
--
N
K
D
G
S
F
L
I
R
K
S
-
S
G
H
D
S
K
Q
P
Y
T
L
V
A
F
F
N
K
R
V
Y
N
I
P
V
R
F
I
E
A
T
K
Q
Y
A
L
G
K
K
K
N
G
E
E
Y
F
G
S
--
V
V
E
I
V
N
S
H
Q
H
N
P
L
V
L
I
D
S
Q
N
-------------------
1
PsiBlast_PDB
66.07
87%
-121
- C1 -
-
2EAP
-
LCP2_HUMAN
A:
[8-90]
-------
M
A
L
R
N
V
P
F
R
S
E
V
L
G
W
D
-
P
D
S
L
A
D
Y
F
K
K
L
N
Y
K
D
C
E
K
A
V
K
K
Y
H
I
D
G
A
R
F
L
N
L
T
E
N
D
I
Q
K
F
P
K
L
R
V
P
I
L
S
K
L
S
Q
E
I
N
K
N
E
E
R
R
S
I
F
T
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
HHSearch
65.78
88%
-121
- C1 -
-
2EAP
-
LCP2_HUMAN
A:
[8-89]
-------
M
A
L
R
N
V
P
F
R
S
E
V
L
G
W
D
-
P
D
S
L
A
D
Y
F
K
K
L
N
Y
K
D
C
E
K
A
V
K
K
Y
H
I
D
G
A
R
F
L
N
L
T
E
N
D
I
Q
K
F
P
K
L
R
V
P
I
L
S
K
L
S
Q
E
I
N
K
N
E
E
R
R
S
I
F
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
HHSearch
63.52
25%
-160
- C1 -
-
1AYA
1
PTN11_MOUSE
B:
[2-100]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
R
W
F
H
P
N
I
T
G
V
E
A
E
N
L
L
L
T
R
--
G
V
D
G
S
F
L
A
R
P
S
-
K
S
N
--
P
G
D
F
T
L
S
V
R
R
N
G
A
V
T
H
I
K
I
Q
N
--
T
G
D
Y
Y
D
L
Y
G
----
G
E
K
F
A
T
--
L
A
E
L
V
Q
Y
Y
M
E
H
H
G
Q
L
K
E
K
N
G
-
D
----
V
I
E
L
K
Y
P
-
L
----
9
PsiBlast_PDB
61.53
34%
-187
- C1 -
-
5EG3
-
?
B:
[7-87]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
E
W
Y
H
A
S
L
T
R
A
Q
A
E
H
M
L
M
R
V
--
P
R
D
G
A
F
L
V
R
----
K
R
N
E
P
N
S
Y
A
I
S
F
R
A
E
G
K
I
K
H
C
R
V
--
Q
Q
E
G
Q
T
V
M
L
G
N
S
-----
E
F
D
S
--
L
V
D
L
I
S
Y
Y
E
K
H
P
L
--------------------------
37
HHSearch
61.08
25%
-154
- C1 -
-
3TKZ
-
PTN11_HUMAN
A:
[7-106]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
R
W
F
H
P
N
I
T
G
V
E
A
E
N
L
L
L
T
R
--
G
V
D
G
S
F
L
A
R
P
S
-
K
S
N
--
P
G
D
F
T
L
S
V
R
R
N
G
A
V
T
H
I
K
I
Q
N
--
T
G
D
Y
Y
D
L
Y
G
----
G
E
K
F
A
T
--
L
A
E
L
V
Q
Y
Y
M
E
H
H
G
Q
L
K
E
K
N
G
-----
D
V
I
E
L
K
Y
P
-
L
N
---
30
Fugue
60.58
17%
171
- C- -
-
4OO3
-
?
A:
[27-465]
-------
E
G
F
T
G
A
P
G
E
V
K
L
I
T
L
D
P
G
H
F
H
A
A
L
V
Q
K
V
S
Y
P
Q
V
S
K
D
V
Y
V
Y
A
P
T
G
--------------------------
F
D
V
D
E
H
L
K
R
I
Q
G
F
N
T
R
A
E
N
P
T
A
W
N
E
I
V
Y
T
G
D
D
--------------------------
Y
L
E
K
M
L
A
E
K
K
G
N
V
M
I
Q
A
G
N
N
G
K
K
T
E
Y
I
K
K
T
L
E
A
G
I
N
V
-------------------
L
S
D
K
P
M
A
I
N
S
Q
S
F
K
L
L
E
E
C
F
A
I
A
K
Q
K
N
I
M
L
Y
D
I
----------------------M
T
E
R
N
E
I
T
T
M
L
Q
R
E
L
S
T
I
---
P
A
V
Y
G
E
Q
L
K
G
S
P
E
E
P
A
-
I
V
K
E
S
V
H
H
L
F
K
L
V
DN
K
P
L
T
R
P
VW
Y
L
D
V
N
Q
Q
G
E
G
I
V
D
V
T
T
H
L
V
D
L
V
Q
W
E
A
F
P
D
Q
I
I
D
Y
R
K
D
I
E
L
I
D
A
N
R
W
T
T
S
I
S
P
E
E
F
K
Q
V
T
G
T
D
A
Y
P
D
F
L
K
K
D
V
E
N
D
T
L
K
V
Y
C
N
G
D
I
V
Y
K
I
K
G
V
T
A
K
V
S
V
I
W
N
Y
T
F
P
K
G
G
G
D
T
H
F
S
V
M
K
G
S
K
A
D
L
V
I
R
Q
--------
G
K
E
Q
N
Y
Q
P
E
L
F
V
E
A
V
K
G
V
D
L
A
A
Y
E
K
D
L
--
T
A
--------
S
M
E
K
V
S
A
E
Y
P
G
V
A
L
N
K
V
G
D
G
V
W
Q
V
E
I
P
A
K
Y
R
----------
V
G
H
E
A
H
F
G
Q
V
T
E
H
F
L
D
Y
L
K
E
G
K
L
P
D
W
E
V
P
N
M
L
A
K
Y
Y
T
T
T
S
A
L
D
M
A
K
A
K
T
11
PsiBlast_PDB
60.38
34%
-181
- C1 -
-
5TO4
-
A:
[8-88]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
E
W
Y
H
A
S
L
T
R
A
Q
A
E
H
M
L
M
R
V
--
P
R
D
G
A
F
L
V
R
----
K
R
N
E
P
N
S
Y
A
I
S
F
R
A
E
G
K
I
K
H
C
R
V
--
Q
Q
E
G
Q
T
V
M
L
G
N
S
-----
E
F
D
S
--
L
V
D
L
I
S
Y
Y
E
K
H
P
L
--------------------------
36
HHSearch
60.34
25%
-170
- C1 -
-
2CIA
2
A:
[5-101]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
E
W
Y
Y
G
N
V
T
R
H
Q
A
E
C
A
L
N
E
R
--
G
V
E
G
D
F
L
I
R
D
S
-
E
S
S
--
P
S
D
F
S
V
S
L
K
A
S
G
K
N
K
H
F
K
V
Q
L
--
V
D
N
V
Y
C
I
G
Q
-----
R
R
F
H
T
--
M
D
E
L
V
E
H
Y
K
K
A
P
I
F
T
S
E
H
G
E
------
K
L
Y
L
V
R
A
-
L
----
15
PsiBlast_PDB
60.29
34%
-201
- C1 -
-
4K45
-
PLCG1_RAT
A:
[6-86]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
E
W
Y
H
A
S
L
T
R
A
Q
A
E
H
M
L
M
R
V
--
P
R
D
G
A
F
L
V
R
----
K
R
N
E
P
N
S
Y
A
I
S
F
R
A
E
G
K
I
K
H
C
R
V
--
Q
Q
E
G
Q
T
V
M
L
G
N
S
-----
E
F
D
S
--
L
V
D
L
I
S
Y
Y
E
K
H
P
L
--------------------------
10
PsiBlast_PDB
60.14
34%
-182
- C1 -
-
5TNW
-
PLCG1_BOVIN
A:
[8-88]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
E
W
Y
H
A
S
L
T
R
A
Q
A
E
H
M
L
M
R
V
--
P
R
D
G
A
F
L
V
R
----
K
R
N
E
P
N
S
Y
A
I
S
F
R
A
E
G
K
I
K
H
C
R
V
--
Q
Q
E
G
Q
T
V
M
L
G
N
S
-----
E
F
D
S
--
L
V
D
L
I
S
Y
Y
E
K
H
P
L
--------------------------
13
PsiBlast_PDB
59.32
34%
-179
- C1 -
-
5TQS
-
PLCG1_BOVIN
A:
[8-88]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
E
W
Y
H
A
S
L
T
R
A
Q
A
E
H
M
L
M
R
V
--
P
R
D
G
A
F
L
V
R
----
K
R
N
E
P
N
S
Y
A
I
S
F
R
A
E
G
K
I
K
H
C
R
V
--
Q
Q
E
G
Q
T
V
M
L
G
N
S
-----
E
F
D
S
--
L
V
D
L
I
S
Y
Y
E
K
H
P
L
--------------------------
41
HHSearch
59.09
26%
-170
- C1 -
-
2RVF
-
?
A:
[5-95]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
S
G
M
A
E
A
A
A
P
W
Y
H
G
P
L
S
R
T
D
A
E
N
S
L
L
-
R
--
M
P
E
G
T
F
L
V
R
D
S
-
T
S
S
--
P
G
D
Y
V
L
S
C
S
E
N
G
K
V
T
H
Y
K
L
S
A
--
E
E
G
K
I
R
I
D
T
-----
H
L
F
D
N
--
L
D
A
A
I
T
F
Y
M
E
H
E
L
E
Y
------------------------
38
HHSearch
58.64
21%
-41
- C1 -
-
5W3R
3
A:
[4-112]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
D
Q
P
L
S
G
Y
P
W
F
H
G
M
L
S
R
L
K
A
A
Q
L
V
L
T
G
GT
G
S
H
G
V
F
L
V
R
Q
S
-
E
T
R
--
R
G
E
Y
V
L
T
F
N
F
Q
G
K
A
K
H
L
R
L
S
L
N
-
A
A
G
Q
C
R
V
Q
-----
H
L
H
F
Q
S
--
I
F
D
M
L
E
H
F
R
V
H
P
I
P
L
E
S
G
G
S
-----
S
D
V
V
L
V
S
Y
-
V
P
---
21
Fugue
58.32
87%
75
- C1 -
-
2EAP
-
LCP2_HUMAN
A:
[1-90]
G
S
S
G
S
S
G
M
A
L
R
N
V
P
F
R
S
E
V
L
G
W
D
-
P
D
S
L
A
D
Y
F
K
K
L
N
Y
K
D
C
E
K
A
V
K
K
Y
H
I
D
G
A
R
F
L
N
L
T
E
N
D
I
Q
K
F
P
K
L
R
V
P
I
L
S
K
L
S
Q
E
I
N
K
N
E
E
R
R
S
I
F
T
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
51
HHSearch
58.05
16%
-179
- C1 -
-
2LNW
-
A:
[15-106]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
E
I
D
Y
T
A
Y
P
W
F
A
G
N
M
E
R
Q
Q
T
D
N
L
L
K
-
S
--
H
A
S
G
T
Y
L
I
R
E
R
-
P
A
E
--
A
E
R
F
A
I
S
I
K
F
N
D
E
V
K
H
I
K
V
V
E
--
K
D
N
W
I
H
I
T
E
----
A
K
K
F
D
S
--
L
L
E
L
V
E
Y
Y
Q
C
H
S
L
K
E
S
-----------------------
12
PsiBlast_PDB
57.82
34%
-179
- C1 -
-
5TQ1
-
A:
[8-88]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
E
W
Y
H
A
S
L
T
R
A
Q
A
E
H
M
L
M
R
V
--
P
R
D
G
A
F
L
V
R
----
K
R
N
E
P
N
S
Y
A
I
S
F
R
A
E
G
K
I
K
H
C
R
V
--
Q
Q
E
G
Q
T
V
M
L
G
N
S
-----
E
F
D
S
--
L
V
D
L
I
S
Y
Y
E
K
H
P
L
--------------------------