@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : VAV_MOUSE: (2018-07-13 )
MELWRQCTHWLIQCRVLPPSHRVTWEGAQVCELAQALRDGVLLCQLLNNLLPQAINLREVNLRPQMSQFLCLKNIRTFLSTCCEKFGLKRSELFEAFDLFDVQDFGKVIYTLSALSWTPIAQNKGIMPFPTEDSALNDEDIYSGLSDQIDDTAEEDEDLYDCVENEEAEGDEIYEDLMRLESVPTPPKMTEYDKRCCCLREIQQTEEKYTDTLGSIQQHFMKPLQRFLKPQDMETIFVNIEELFSVHTHFLKELKDALAGPGATTLYQVFIKYKERFLVYGRYCSQVESASKHLDQVATAREDVQMKLEECSQRANNGRFTLRDLLMVPMQRVLKYHLLLQELVKHTQDATEKENLRLALDAMRDLAQCVNEVKRDNETLRQITNFQLSIENLDQSLANYGRPKIDGELKITSVERRSKTDRYAFLLDKALLICKRRGDSYDLKASVNLHSFQVRDDSSGERDNKKWSHMFLLIEDQGAQGYELFFKTRELKKKWMEQFEMAISNIYPENATANGHDFQMFSFEETTSCKACQMLLRGTFYQGYRCYRCRAPAHKECLGRVPPCGRHGQDFAGTMKKDKLHRRAQDKKRNELGLPKMEVFQEYYGIPPPPGAFGPFLRLNPGDIVELTKAEAEHNWWEGRNTATNEVGWFPCNRVHPYVHGPPQDLSVHLWYAGPMERAGAEGILTNRSDGTYLVRQRVKDTAEFAISIKYNVEVKHIKIMTSEGLYRITEKKAFRGLLELVEFYQQNSLKDCFKSLDTTLQFPYKEPERRAISKPPAGSTKYFGTAKARYDFCARDRSELSLKEGDIIKILNKKGQQGWWRGEIYGRIGWFPSNYVEEDYSEYC
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220...---.--------..-----.---230.......240.......-250......--.----260-------.-.-------------.......270.-----..------.------...280.......290.......300.......310--.......320.......330.......340......-.-350.......360.......370.......380...--....390.-.------------.------------.--.-----------.-.400.-.......410....-----...420.......430....---.---.----------.-------------------440..------.....450.......460--.----......470....------....480.......--490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690.......700.......710.......720.......730.......740.......750.......760.......770.......780.......790.......800.......810.......820.......830.......840...
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
M
E
L
W
R
Q
C
T
H
W
L
I
Q
C
R
VLPPS
H
R
V
TWE
G
A
Q
V
C
E
L
A
Q
A
L
R
D
G
V
L
L
C
Q
L
L
N
N
L
L
PQAI
N
L
R
E
VNLR
P
Q
M
S
Q
F
L
C
L
K
N
I
R
T
F
L
S
T
C
C
E
K
FGL
K
R
S
E
L
F
E
A
F
D
LF
D
V
Q
D
F
G
K
V
I
Y
T
L
SAL
S
W
TPIAQNKGIMPFPTEDSAL
N
D
E
D
I
Y
S
G
L
S
D
QIDDTA
E
E
D
E
D
L
Y
D
C
VENEEAE
G
D
E
I
Y
E
D
L
M
R
L
ESVPTPPKM
T
E
Y
D
K
R
C
C
C
L
R
E
I
Q
Q
T
E
E
K
Y
T
D
T
L
G
S
I
Q
Q
H
F
M
K
P
L
Q
---
R
--------FL-----K---PQD
M
E
T
I
F
V
N
I
E
E
L
F
S
V
H
T
H
-
F
L
K
E
L
K
D
A
L--A----G---------P-
G
-------------
A
T
T
L
Y
Q
V
F
I
K
Y
-----
K
E
------
R
------
F
L
V
Y
G
R
Y
C
S
Q
V
E
S
A
S
K
H
L
D
Q
V
A
T
A
R
E
D
V
Q
M
K
L
E
E
C
S
--
Q
R
ANNGR
F
T
L
R
D
L
L
M
V
P
M
Q
R
V
L
K
Y
H
L
L
L
Q
E
L
V
K
HTQ-D-A
T
E
K
E
N
L
R
L
A
L
D
A
M
R
D
L
A
Q
C
V
N
E
V
KR
D
N
E
T
L
R
Q
I
TN--
F
Q
L
S
I
E
N
L
-
D
------------
Q
------------
S
--
L
-----------
A
-NY-GR-PKIDG
E
L
K
I
T
S
V
ER-----RSKT
D
R
Y
A
F
L
L
D
K
A
L
L
I
C
KR---R---G----------D-------------------SY
D
L
K
------
A
S
V
N
L
H
S
F
Q
VRDDSSGER--D----NKK
W
S
H
M
F
-
L
L
I
E------DQGAQ
G
Y
E
L
F
F
K
T
R
--
E
L
K
K
K
W
M
E
Q
F
E
M
A
I
S
NIYPENATANGHD
F
Q
M
F
S
FEETT
S
C
K
A
C
Q
M
L
L
R
G
TFYQ
G
Y
R
C
Y
RCRAP
A
H
K
E
C
L
GRVPPCGRH
G
Q
D
F
A
G
T
M
K
K
D
K
L
H
R
R
A
Q
DKKRNELGL
P
K
M
E
V
F
Q
E
Y
YGIPPPPGAFGP
F
L
RLNPG
D
I
V
E
L
TKAEAEHNWWEGRNTATNEVGWFPCNRVHPYVHGPPQD
L
S
V
H
L
W
YAG
P
M
E
RAGAE
G
I
LTNRSD
G
T
Y
L
V
R
Q
R
V
KDT
A
E
F
A
I
S
I
K
Y
N
V
E
V
K
H
I
K
I
MTSEG
L
Y
R
I
T
E
K
K
A
F
R
G
L
L
E
L
V
E
F
Y
Q
QN
S
L
K
D
C
F
K
S
L
D
T
TLQFPYKEPERRAISKPPAGST
K
Y
F
GTAKA
R
Y
D
F
CAR
D
R
S
ELSLKEG
D
I
I
K
I
L
NKKGQQGWWRG
E
I
Y
G
RIGWF
P
S
N
Y
V
E
E
D
Y
SEYC
1
PsiBlast_PDB
93.84
93%
-139
- C2 -
-
3KY9
-
VAV_HUMAN
A:
[5-567]
-
E
L
W
R
Q
C
T
H
W
L
I
Q
C
R
V
L
P
P
S
H
R
V
T
W
E
G
A
Q
V
C
E
L
A
Q
A
L
R
D
G
V
L
L
C
Q
L
L
N
N
L
L
P
H
A
I
N
L
R
E
V
N
L
R
P
Q
M
S
Q
F
L
C
L
K
N
I
R
T
F
L
S
T
C
C
E
K
F
G
L
K
R
S
E
L
F
E
A
F
D
L
F
D
V
Q
D
F
G
K
V
I
Y
T
L
S
A
L
S
W
T
P
I
A
Q
N
R
G
I
M
P
F
------------
Y
S
G
L
S
D
Q
I
D
D
-----
E
D
L
Y
D
C
V
E
N
E
E
A
E
G
D
E
I
Y
E
D
L
M
R
S
--------
M
T
E
Y
D
K
R
C
C
C
L
R
E
I
Q
Q
T
E
E
K
Y
T
D
T
L
G
S
I
Q
Q
H
F
L
K
P
L
Q
---
R
--------
F
L
-----
K
---
P
Q
D
I
E
I
I
F
I
N
I
E
D
L
L
R
V
H
T
H
-
F
L
K
E
M
K
E
A
L
--
G
----
T
---------
P
-
G
-------------
A
A
N
L
Y
Q
V
F
I
K
Y
-----
K
E
------
R
------
F
L
V
Y
G
R
Y
C
S
Q
V
E
S
A
S
K
H
L
D
R
V
A
A
A
R
E
D
V
Q
M
K
L
E
E
C
S
--
Q
R
A
N
N
G
R
F
T
L
R
D
L
L
M
V
P
M
Q
R
V
L
K
Y
H
L
L
L
Q
E
L
V
K
H
T
Q
-
E
-
A
M
E
K
E
N
L
R
L
A
L
D
A
M
R
D
L
A
Q
C
V
N
E
V
K
R
D
N
E
T
L
R
Q
I
T
N
--
F
Q
L
S
I
E
N
L
-
D
------------
Q
------------
S
--
L
-----------
A
-
H
Y
-
G
R
-
P
K
I
D
G
E
L
K
I
T
S
V
E
R
-----
R
S
K
M
D
R
Y
A
F
L
L
D
K
A
L
L
I
C
K
R
---
R
---
G
----------
D
-------------------
S
Y
D
L
K
------
D
F
V
N
L
H
S
F
Q
V
R
D
D
-------
D
----
N
K
K
W
S
H
M
F
-
L
L
I
E
------
D
Q
---
G
Y
E
L
F
F
K
T
R
--
E
L
K
K
K
W
M
E
Q
F
E
M
A
I
S
N
I
Y
P
E
N
A
T
A
N
G
H
D
F
Q
M
F
S
F
E
E
T
T
S
C
K
A
C
Q
M
L
L
R
G
T
F
Y
Q
G
Y
R
C
H
R
C
R
A
S
A
H
K
E
C
L
G
R
V
P
P
C
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
HHSearch
78.68
100%
-130
- C2 -
-
2VRW
-
VAV_MOUSE
B:
[21-395]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
E
Y
D
K
R
C
C
C
L
R
E
I
Q
Q
T
E
E
K
Y
T
D
T
L
G
S
I
Q
Q
H
F
M
K
P
L
Q
---
R
--------
F
L
-----
K
---
P
Q
D
M
E
T
I
F
V
N
I
E
E
L
F
S
V
H
T
H
-
F
L
K
E
L
K
D
A
L
--
A
----
G
---------
P
-
G
-------------
A
T
T
L
Y
Q
V
F
I
K
Y
-----
K
E
------
R
------
F
L
V
Y
G
R
Y
C
S
Q
V
E
S
A
S
K
H
L
D
Q
V
A
T
A
R
E
D
V
Q
M
K
L
E
E
C
S
--
Q
R
A
N
N
G
R
F
T
L
R
D
L
L
M
V
P
M
Q
R
V
L
K
Y
H
L
L
L
Q
E
L
V
K
H
T
Q
-
D
-
A
T
E
K
E
N
L
R
L
A
L
D
A
M
R
D
L
A
Q
C
V
N
E
V
K
R
D
N
E
T
L
R
Q
I
T
N
--
F
Q
L
S
I
E
N
L
-
D
------------
Q
------------
S
--
L
-----------
A
-
N
Y
-
G
R
-
P
K
I
D
G
E
L
K
I
T
S
V
E
R
-----
R
S
K
T
D
R
Y
A
F
L
L
D
K
A
L
L
I
C
K
R
---
R
---
G
----------
D
-------------------
S
Y
D
L
K
------
A
S
V
N
L
H
S
F
Q
V
R
D
--------------
K
K
W
S
H
M
F
-
L
L
I
E
------
D
Q
G
A
Q
G
Y
E
L
F
F
K
T
R
--
E
L
K
K
K
W
M
E
Q
F
E
M
A
I
S
N
I
Y
P
E
N
A
T
A
N
G
H
D
F
Q
M
F
S
F
E
E
T
T
S
C
K
A
C
Q
M
L
L
R
G
T
F
Y
Q
G
Y
R
C
Y
R
C
R
A
P
A
H
K
E
C
L
G
R
V
P
P
C
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
78.68
100%
-130
- C2 -
-
2VRW
-
VAV_MOUSE
B:
[21-395]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
E
Y
D
K
R
C
C
C
L
R
E
I
Q
Q
T
E
E
K
Y
T
D
T
L
G
S
I
Q
Q
H
F
M
K
P
L
Q
---
R
--------
F
L
-----
K
---
P
Q
D
M
E
T
I
F
V
N
I
E
E
L
F
S
V
H
T
H
-
F
L
K
E
L
K
D
A
L
--
A
----
G
---------
P
-
G
-------------
A
T
T
L
Y
Q
V
F
I
K
Y
-----
K
E
------
R
------
F
L
V
Y
G
R
Y
C
S
Q
V
E
S
A
S
K
H
L
D
Q
V
A
T
A
R
E
D
V
Q
M
K
L
E
E
C
S
--
Q
R
A
N
N
G
R
F
T
L
R
D
L
L
M
V
P
M
Q
R
V
L
K
Y
H
L
L
L
Q
E
L
V
K
H
T
Q
-
D
-
A
T
E
K
E
N
L
R
L
A
L
D
A
M
R
D
L
A
Q
C
V
N
E
V
K
R
D
N
E
T
L
R
Q
I
T
N
--
F
Q
L
S
I
E
N
L
-
D
------------
Q
------------
S
--
L
-----------
A
-
N
Y
-
G
R
-
P
K
I
D
G
E
L
K
I
T
S
V
E
R
-----
R
S
K
T
D
R
Y
A
F
L
L
D
K
A
L
L
I
C
K
R
---
R
---
G
----------
D
-------------------
S
Y
D
L
K
------
A
S
V
N
L
H
S
F
Q
V
R
D
--------------
K
K
W
S
H
M
F
-
L
L
I
E
------
D
Q
G
A
Q
G
Y
E
L
F
F
K
T
R
--
E
L
K
K
K
W
M
E
Q
F
E
M
A
I
S
N
I
Y
P
E
N
A
T
A
N
G
H
D
F
Q
M
F
S
F
E
E
T
T
S
C
K
A
C
Q
M
L
L
R
G
T
F
Y
Q
G
Y
R
C
Y
R
C
R
A
P
A
H
K
E
C
L
G
R
V
P
P
C
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
77.89
93%
-134
- C2 -
-
3BJI
-
VAV_HUMAN
A:
[1-377]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
T
E
Y
D
K
R
C
C
C
L
R
E
I
Q
Q
T
E
E
K
Y
T
D
T
L
G
S
I
Q
Q
H
F
L
K
P
L
Q
---
R
--------
F
L
-----
K
---
P
Q
D
I
E
I
I
F
I
N
I
E
D
L
L
R
V
H
T
H
-
F
L
K
E
M
K
E
A
L
--
G
----
T
---------
P
-
G
-------------
A
A
N
L
Y
Q
V
F
I
K
Y
-----
K
E
------
R
------
F
L
V
Y
G
R
Y
C
S
Q
V
E
S
A
S
K
H
L
D
R
V
A
A
A
R
E
D
V
Q
M
K
L
E
E
C
S
--
Q
R
A
N
N
G
R
F
T
L
R
D
L
L
M
V
P
M
Q
R
V
L
K
Y
H
L
L
L
Q
E
L
V
K
H
T
Q
-
E
-
A
M
E
K
E
N
L
R
L
A
L
D
A
M
R
D
L
A
Q
C
V
N
E
V
K
R
D
N
E
T
L
R
Q
I
T
N
--
F
Q
L
S
I
E
N
L
-
D
------------
Q
------------
S
--
L
-----------
A
-
H
Y
-
G
R
-
P
K
I
D
G
E
L
K
I
T
S
V
E
R
-----
R
S
K
M
D
R
Y
A
F
L
L
D
K
A
L
L
I
C
K
R
---
R
---
G
----------
D
-------------------
S
Y
D
L
K
------
D
F
V
N
L
H
S
F
Q
V
R
D
D
-------
D
----
N
K
K
W
S
H
M
F
-
L
L
I
E
------
D
Q
G
A
Q
G
Y
E
L
F
F
K
T
R
--
E
L
K
K
K
W
M
E
Q
F
E
M
A
I
S
N
I
Y
P
E
N
A
T
A
N
G
H
D
F
Q
M
F
S
F
E
E
T
T
S
C
K
A
C
Q
M
L
L
R
G
T
F
Y
Q
G
Y
R
C
H
R
C
R
A
S
A
H
K
E
C
L
G
R
V
P
P
C
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
HHSearch
77.85
93%
-133
- C2 -
-
3BJI
-
VAV_HUMAN
A:
[2-377]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
E
Y
D
K
R
C
C
C
L
R
E
I
Q
Q
T
E
E
K
Y
T
D
T
L
G
S
I
Q
Q
H
F
L
K
P
L
Q
---
R
--------
F
L
-----
K
---
P
Q
D
I
E
I
I
F
I
N
I
E
D
L
L
R
V
H
T
H
-
F
L
K
E
M
K
E
A
L
--
G
----
T
---------
P
-
G
-------------
A
A
N
L
Y
Q
V
F
I
K
Y
-----
K
E
------
R
------
F
L
V
Y
G
R
Y
C
S
Q
V
E
S
A
S
K
H
L
D
R
V
A
A
A
R
E
D
V
Q
M
K
L
E
E
C
S
--
Q
R
A
N
N
G
R
F
T
L
R
D
L
L
M
V
P
M
Q
R
V
L
K
Y
H
L
L
L
Q
E
L
V
K
H
T
Q
-
E
-
A
M
E
K
E
N
L
R
L
A
L
D
A
M
R
D
L
A
Q
C
V
N
E
V
K
R
D
N
E
T
L
R
Q
I
T
N
--
F
Q
L
S
I
E
N
L
-
D
------------
Q
------------
S
--
L
-----------
A
-
H
Y
-
G
R
-
P
K
I
D
G
E
L
K
I
T
S
V
E
R
-----
R
S
K
M
D
R
Y
A
F
L
L
D
K
A
L
L
I
C
K
R
---
R
---
G
----------
D
-------------------
S
Y
D
L
K
------
D
F
V
N
L
H
S
F
Q
V
R
D
D
-------
D
----
N
K
K
W
S
H
M
F
-
L
L
I
E
------
D
Q
G
A
Q
G
Y
E
L
F
F
K
T
R
--
E
L
K
K
K
W
M
E
Q
F
E
M
A
I
S
N
I
Y
P
E
N
A
T
A
N
G
H
D
F
Q
M
F
S
F
E
E
T
T
S
C
K
A
C
Q
M
L
L
R
G
T
F
Y
Q
G
Y
R
C
H
R
C
R
A
S
A
H
K
E
C
L
G
R
V
P
P
C
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
61.35
99%
-152
- C2 -
-
1F5X
-
VAV_MOUSE
A:
[2-208]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
G
D
E
I
Y
E
D
L
M
R
L
E
S
V
P
T
P
P
K
M
T
E
Y
D
K
R
C
C
C
L
R
E
I
Q
Q
T
E
E
K
Y
T
D
T
L
G
S
I
Q
Q
H
F
M
K
P
L
Q
---
R
--------
F
L
-----
K
---
P
Q
D
M
E
T
I
F
V
N
I
E
E
L
F
S
V
H
T
H
-
F
L
K
E
L
K
D
A
L
--
A
----
G
---------
P
-
G
-------------
A
T
T
L
Y
Q
V
F
I
K
Y
-----
K
E
------
R
------
F
L
V
Y
G
R
Y
C
S
Q
V
E
S
A
S
K
H
L
D
Q
V
A
T
A
R
E
D
V
Q
M
K
L
E
E
C
S
--
Q
R
A
N
N
G
R
F
T
L
R
D
L
L
M
V
P
M
Q
R
V
L
K
Y
H
L
L
L
Q
E
L
V
K
H
T
Q
-
D
-
A
T
E
K
E
N
L
R
L
A
L
D
A
M
R
D
L
A
Q
C
V
N
E
V
K
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
50
HHSearch
51.52
28%
28
- C2 -
-
5FI0
-
PREX1_HUMAN
G:
[9-363]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
E
R
Q
L
R
L
R
L
C
V
L
N
E
I
L
G
T
E
R
D
Y
V
G
T
L
R
F
L
Q
S
A
F
L
H
R
I
R
---
Q
N
V
A
D
S
V
E
K
G
L
-----
T
---
E
E
N
V
K
V
L
F
S
N
I
E
D
I
L
E
V
H
K
D
-
F
L
A
A
L
E
Y
C
L
--
H
PE--
P
---------
Q
-
S
-------------
Q
H
E
L
G
N
V
F
L
K
F
-----
K
D
------
K
------
F
C
V
Y
E
E
Y
C
S
N
H
E
K
A
L
R
L
L
V
E
L
N
-
K
I
P
T
V
R
A
F
L
L
S
C
M
L
L
G
G
R
K
T
T
D
I
P
L
E
G
Y
L
L
S
P
I
Q
R
I
C
K
Y
P
L
L
L
K
E
L
A
K
R
T
P
-
G
K
H
P
D
H
P
A
V
Q
S
A
L
Q
A
M
K
T
V
C
S
N
I
N
E
T
K
R
Q
M
E
K
L
E
A
L
E
Q
--
L
Q
S
H
I
E
G
W
E
G
------------
S
------------
N
--
L
-----------
T
-
D
I
C
T
Q
-
L
L
L
Q
G
T
L
L
K
I
S
A
-------
G
N
I
Q
E
R
A
F
F
L
F
D
N
L
L
V
Y
C
K
R
---
K
---
S
------------------------------
L
Y
I
F
R
------
G
R
I
N
T
E
V
M
E
V
E
N
V
E
D
G
T
A
--
D
YHSN
G
Y
T
V
T
N
G
W
-
K
I
H
N
------
T
A
K
N
K
W
F
V
C
M
A
K
T
A
--
E
E
K
Q
K
W
L
D
A
I
I
R
E
R
E
Q
R
E
S
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
42
HHSearch
51.36
23%
16
- C2 -
-
2DFK
-
ARHG9_RAT
C:
[36-369]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
N
R
D
Q
M
R
A
N
V
I
N
E
I
M
S
T
E
R
H
Y
I
K
H
L
K
D
I
C
E
G
Y
L
K
Q
C
R
K
R
R
D
--------
M
F
-----
S
---
D
E
Q
L
K
V
I
F
G
N
I
E
D
I
Y
R
F
Q
M
G
-
F
V
R
D
L
E
K
Q
Y
--
N
----
N
DD-------
P
-
H
-------------
L
S
E
I
G
P
C
F
L
E
H
-----
Q
D
------
G
------
F
W
I
Y
S
E
Y
C
N
N
H
L
D
A
C
M
E
L
S
K
L
M
K
-
D
S
R
Y
Q
H
F
F
E
A
C
R
--
L
L
Q
Q
M
I
D
I
A
I
D
G
F
L
L
T
P
V
Q
K
I
C
K
Y
P
L
Q
L
A
E
L
L
K
Y
T
A
-
Q
D
H
S
D
Y
R
Y
V
A
A
A
L
A
V
M
R
N
V
T
Q
Q
I
N
E
R
K
R
R
L
E
N
I
D
K
I
A
Q
--
W
Q
A
S
V
L
D
W
E
G
------------
D
------------
D
--
I
L----------
D
-
R
S
-
S
E
-
L
I
Y
T
G
E
M
A
W
I
Y
Q
P
Y
-----
G
R
N
Q
Q
R
V
F
F
L
F
D
H
Q
M
V
L
C
K
K
---
D
LIR
R
----------
D
-------------------
I
L
Y
Y
K
------
G
R
I
D
M
D
K
Y
E
V
I
D
I
E
D
G
R
D
DD
F
----
N
V
S
M
K
N
A
F
-
K
L
H
N
------
K
E
T
E
E
V
H
L
F
F
A
K
K
L
--
E
E
K
I
R
W
L
R
A
F
R
E
E
R
K
M
V
Q
E
D
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
HHSearch
51.17
25%
25
- C2 -
-
2PZ1
-
ARHG4_HUMAN
A:
[278-611]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
S
S
K
D
Q
M
R
T
N
V
I
N
E
I
L
S
T
E
R
D
Y
I
K
H
L
R
D
I
C
E
G
Y
V
R
Q
C
R
K
R
A
D
--------
M
F
-----
S
---
E
E
Q
L
R
T
I
F
G
N
I
E
D
I
Y
R
C
Q
K
A
-
F
V
K
A
L
E
Q
R
F
--
N
RE--
R
---------
P
-
H
-------------
L
S
E
L
G
A
C
F
L
E
H
-----
Q
A
------
D
------
F
Q
I
Y
S
E
Y
C
N
N
H
P
N
A
C
V
E
L
S
R
L
T
K
L
-
S
K
Y
V
Y
F
F
E
A
C
R
--
L
L
Q
K
M
I
D
I
S
L
D
G
F
L
L
T
P
V
Q
K
I
C
K
Y
P
L
Q
L
A
E
L
L
K
Y
T
H
-
P
Q
H
R
D
F
K
D
V
E
A
A
L
H
A
M
K
N
V
A
Q
L
I
N
E
R
K
R
R
L
E
N
I
D
K
I
A
Q
--
W
Q
S
S
I
E
D
W
E
G
------------
E
------------
D
--
L
-----------
L
-
V
R
S
S
E
-
L
I
Y
S
G
E
L
T
R
V
T
Q
P
Q
-----
A
K
S
Q
Q
R
M
F
F
L
F
D
H
Q
L
I
Y
C
K
K
---
D
LLR
R
----------
D
-------------------
V
L
Y
Y
K
------
G
R
L
D
M
D
G
L
E
V
V
D
L
E
D
G
K
D
--
R
DL--
H
V
S
I
K
N
A
F
-
R
L
H
R
------
G
A
T
G
D
S
H
L
L
C
T
R
K
P
--
E
Q
K
Q
R
W
L
K
A
F
A
R
E
R
E
Q
V
Q
L
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
50.49
26%
22
- C2 -
-
2PZ1
-
ARHG4_HUMAN
A:
[285-601]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
T
N
V
I
N
E
I
L
S
T
E
R
D
Y
I
K
H
L
R
D
I
C
E
G
Y
V
R
Q
C
R
---
K
R
AD-----
M
F
-----
S
---
E
E
Q
L
R
T
I
F
G
N
I
E
D
I
Y
R
C
Q
K
A
-
F
V
K
A
L
E
Q
R
F
NR
E
----
R
---------
P
-
H
-------------
L
S
E
L
G
A
C
F
L
E
H
-----
Q
A
------
D
------
F
Q
I
Y
S
E
Y
C
N
N
H
P
N
A
C
V
E
L
S
R
L
T
K
L
S
K
Y
V
Y
F
-
F
E
A
C
R
--
L
L
Q
K
M
I
D
I
S
L
D
G
F
L
L
T
P
V
Q
K
I
C
K
Y
P
L
Q
L
A
E
L
L
K
Y
T
H
P
Q
-
H
R
D
F
K
D
V
E
A
A
L
H
A
M
K
N
V
A
Q
L
I
N
E
R
K
R
R
L
E
N
I
D
K
I
A
Q
--
W
Q
S
S
I
E
D
W
-
E
------------
G
------------
E
D
L
L
-----------
V
-
R
S
-
S
E
-
L
I
Y
S
G
E
L
T
R
V
T
Q
P
Q
-----
A
K
S
Q
Q
R
M
F
F
L
F
D
H
Q
L
I
Y
C
K
K
D
LL
R
---
R
----------
D
-------------------
V
L
Y
Y
K
------
G
R
L
D
M
D
G
L
E
V
V
D
L
E
D
G
K
D
--
R
----
D
L
H
V
S
I
K
N
-
A
F
R
L
------
H
R
G
A
T
G
D
S
H
L
L
C
T
R
K
P
E
Q
K
Q
R
W
L
K
A
F
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
43
HHSearch
49.76
23%
18
- C2 -
-
2DFK
3
ARHG9_RAT
A:
[35-369]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Q
N
R
D
Q
M
R
A
N
V
I
N
E
I
M
S
T
E
R
H
Y
I
K
H
L
K
D
I
C
E
G
Y
L
K
Q
C
R
K
R
R
D
--------
M
F
-----
S
---
D
E
Q
L
K
V
I
F
G
N
I
E
D
I
Y
R
F
Q
M
G
-
F
V
R
D
L
E
K
Q
Y
--
N
----
N
DD-------
P
-
H
-------------
L
S
E
I
G
P
C
F
L
E
H
-----
Q
D
------
G
------
F
W
I
Y
S
E
Y
C
N
N
H
L
D
A
C
M
E
L
S
K
L
M
K
-
D
S
R
Y
Q
H
F
F
E
A
C
R
--
L
L
Q
Q
M
I
D
I
A
I
D
G
F
L
L
T
P
V
Q
K
I
C
K
Y
P
L
Q
L
A
E
L
L
K
Y
T
A
-
Q
D
H
S
D
Y
R
Y
V
A
A
A
L
A
V
M
R
N
V
T
Q
Q
I
N
E
R
K
R
R
L
E
N
I
D
K
I
A
Q
--
W
Q
A
S
V
L
D
W
E
G
------------
D
------------
D
--
I
L----------
D
-
R
S
-
S
E
-
L
I
Y
T
G
E
M
A
W
I
Y
Q
P
Y
-----
G
R
N
Q
Q
R
V
F
F
L
F
D
H
Q
M
V
L
C
K
K
---
D
LIR
R
----------
D
-------------------
I
L
Y
Y
K
------
G
R
I
D
M
D
K
Y
E
V
I
D
I
E
D
G
R
D
DD
F
----
N
V
S
M
K
N
A
F
-
K
L
H
N
------
K
E
T
E
E
V
H
L
F
F
A
K
K
L
--
E
E
K
I
R
W
L
R
A
F
R
E
E
R
K
M
V
Q
E
D
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
HHSearch
49.30
21%
25
- C2 -
-
1X86
-
ARHGC_HUMAN
C:
[5-375]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
W
Q
Q
L
V
S
R
E
V
L
L
G
--
L
K
P
C
E
I
K
R
Q
E
V
I
N
E
L
F
Y
T
E
R
A
H
V
R
T
L
K
V
L
D
Q
V
F
Y
Q
R
V
S
R
E
-
G
--------
I
L
-----
S
---
P
S
E
L
R
K
I
F
S
N
L
E
D
I
L
Q
L
H
I
G
-
L
N
E
Q
M
K
A
V
R
--
K
R
N
E-
T
---------
S
-
V
-------------
I
D
Q
I
G
E
D
L
L
T
W
-----
F
S
G
P
G
E
E
K
L
------
K
H
A
A
A
T
F
C
S
N
Q
P
F
A
L
E
M
I
K
S
R
Q
K
K
D
S
R
F
Q
T
F
V
Q
D
A
E
--
S
N
P
L
C
R
R
L
Q
L
K
D
I
I
P
T
Q
M
Q
R
L
T
K
Y
P
L
L
L
D
N
I
A
K
Y
T
E
-
W
-
P
T
E
R
E
K
V
K
K
A
A
D
H
C
R
Q
I
L
N
F
V
N
Q
A
V
K
E
A
E
N
K
Q
R
L
E
D
--
Y
Q
R
R
L
D
T
S
-
S
------------
L
K
L
S
EYPNV
E
E
L
R
N
--
L
-----------
D
-
L
T
K
R
K
-
M
I
H
E
G
P
L
V
W
K
V
N
R
------
D
K
T
I
D
L
Y
T
L
L
L
E
D
I
L
V
L
L
Q
K
---
Q
---
D
----------
D
R
L
V
L
R
C
HS-------------
T
F
S
------
P
V
I
K
L
S
T
V
L
V
R
Q
V
A
T
D
N
------------
K
A
L
F
-
V
I
S
M
S
-----
D
N
G
A
Q
I
Y
E
L
V
A
Q
T
V
--
S
E
K
T
V
W
Q
D
L
I
C
R
M
A
A
S
V
K
E
Q
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
48.54
72%
-197
- C2 -
-
2D86
-
VAV3_HUMAN
A:
[8-142]
M
E
P
W
K
Q
C
A
Q
W
L
I
H
C
K
V
L
P
T
N
H
R
V
T
W
D
S
A
Q
V
F
D
L
A
Q
T
L
R
D
G
V
L
L
C
Q
L
L
N
N
L
R
A
H
S
I
N
L
K
E
I
N
L
R
P
Q
M
S
Q
F
L
C
L
K
N
I
R
T
F
L
T
A
C
C
E
T
F
G
M
R
K
S
E
L
F
E
A
F
D
L
F
D
V
R
D
F
G
K
V
I
E
T
L
S
R
L
S
R
T
P
I
A
L
A
T
G
I
R
P
F
P
S
G
P
S
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
HHSearch
47.67
17%
19
* C2 *
-
4D0N
1
B:
[8-371]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
E
S
W
S
R
I
I
D
S
K
F
L
K
Q
--
Q
K
K
D
V
V
K
R
Q
E
V
I
Y
E
L
M
Q
T
E
F
H
H
V
R
T
L
K
I
M
S
G
V
Y
S
Q
G
M
M
---
A
DL------
L
F
-----
E
---
Q
Q
M
V
E
K
L
F
P
C
L
D
E
L
I
S
I
H
S
Q
-
F
F
Q
R
I
L
E
R
K
--
K
----
E
S
LVDKSEK
N
F
-
L
-------------
I
K
R
I
G
D
V
L
V
N
Q
F
S
G
E
N
A
E
R
-----
L
------
K
K
T
Y
G
K
F
C
G
Q
H
N
Q
S
V
N
Y
F
K
D
L
Y
A
K
D
K
R
F
Q
A
F
V
K
K
K
M
--
S
S
S
V
V
R
R
L
G
I
P
E
C
I
L
L
V
T
Q
R
I
T
K
Y
P
V
L
F
Q
R
I
L
Q
C
T
K
-
D
N
E
V
E
Q
E
D
L
A
Q
S
L
S
L
V
K
D
V
I
G
A
V
D
S
K
V
A
S
Y
E
K
K
V
R
L
N
E
--
I
Y
T
K
T
D
S
K
-
S
------------
I
------------
M
--
R
M
KSG
Q
M
F
A
KED
L
-
K
R
-
K
K
-
L
V
R
D
G
S
V
F
L
K
N
A
A
------
G
R
L
K
E
V
Q
A
V
L
L
T
D
I
L
V
F
L
Q
E
---
K
---
D
----------
Q
-------------------
K
Y
I
F
A
SLDQKS
T
V
I
S
L
K
K
L
I
V
R
E
V
A
H
E
E
------------
K
G
L
F
-
L
I
S
M
G-----
M
T
D
P
E
M
V
E
V
H
A
S
S
K
--
E
E
R
N
S
W
I
Q
I
I
Q
D
T
I
N
T
L
N
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
44
HHSearch
47.52
23%
29
- C2 -
-
5JHH
1
E:
[16-368]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
T
Q
R
E
I
D
R
Q
E
V
I
N
E
L
F
V
T
E
A
S
H
L
R
T
L
R
V
L
D
L
I
F
Y
Q
R
M
K
KE-
N
--------
L
M
-----
P
---
R
E
E
L
A
R
L
F
P
N
L
P
E
L
I
E
I
H
N
S
-
W
C
E
A
M
K
K
L
R
--
E
E---
G
---------
P
-
I
-------------
I
K
E
I
S
D
L
M
L
A
R
-----
F
D
------
G
PAREEL
Q
Q
V
A
A
Q
F
C
S
Y
Q
S
I
A
L
E
L
I
K
T
K
Q
R
K
E
S
R
F
Q
L
F
M
Q
E
A
E
--
S
H
P
Q
C
R
R
L
Q
L
R
D
L
I
I
S
E
M
Q
R
L
T
K
Y
P
L
L
L
E
S
I
I
K
H
T
E
-
G
G
T
S
E
H
E
K
L
C
R
A
R
D
Q
C
R
E
I
L
K
Y
V
N
E
A
V
K
Q
T
E
N
R
H
R
L
E
G
--
Y
Q
K
R
L
D
A
T
-
A
LERASNPLAAEF
K
------------
S
--
L
-----------
D
L
T
T
-
R
K
-
M
I
H
E
G
P
L
T
W
R
I
S
K
------
D
K
T
L
D
L
H
V
L
L
L
E
D
L
L
V
L
L
Q
K
---
Q
---
D
EKLLLKCHSK----------------------
T
F
S
------
P
V
L
K
L
N
A
V
L
I
R
S
V
A
T
D
-------------
K
R
A
F
-
F
I
I
C
TSK---
L
G
P
P
Q
I
Y
E
L
V
A
L
T
S
--
S
D
K
N
T
W
M
E
L
L
E
E
A
V
R
N
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
HHSearch
47.19
23%
29
- C2 -
-
1XCG
-
ARHGB_HUMAN
E:
[728-1080]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
T
Q
R
E
I
D
R
Q
E
V
I
N
E
L
F
V
T
E
A
S
H
L
R
T
L
R
V
L
D
L
I
F
Y
Q
R
M
K
KE-
N
--------
L
M
-----
P
---
R
E
E
L
A
R
L
F
P
N
L
P
E
L
I
E
I
H
N
S
-
W
C
E
A
M
K
K
L
R
--
E
E---
G
---------
P
-
I
-------------
I
K
E
I
S
D
L
M
L
A
R
-----
F
D
------
G
PAREEL
Q
Q
V
A
A
Q
F
C
S
Y
Q
S
I
A
L
E
L
I
K
T
K
Q
R
K
E
S
R
F
Q
L
F
M
Q
E
A
E
--
S
H
P
Q
C
R
R
L
Q
L
R
D
L
I
I
S
E
M
Q
R
L
T
K
Y
P
L
L
L
E
S
I
I
K
H
T
E
-
G
G
T
S
E
H
E
K
L
C
R
A
R
D
Q
C
R
E
I
L
K
Y
V
N
E
A
V
K
Q
T
E
N
R
H
R
L
E
G
--
Y
Q
K
R
L
D
A
T
-
A
LERASNPLAAEF
K
------------
S
--
L
-----------
D
L
T
T
-
R
K
-
M
I
H
E
G
P
L
T
W
R
I
S
K
------
D
K
T
L
D
L
H
V
L
L
L
E
D
L
L
V
L
L
Q
K
---
Q
---
D
EKLLLKCHSK----------------------
T
F
S
------
P
V
L
K
L
N
A
V
L
I
R
S
V
A
T
D
-------------
K
R
A
F
-
F
I
I
C
TSK---
L
G
P
P
Q
I
Y
E
L
V
A
L
T
S
--
S
D
K
N
T
W
M
E
L
L
E
E
A
V
R
N
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
47
HHSearch
46.65
20%
34
- C2 -
-
1KI1
-
ITSN1_HUMAN
B:
[3-348]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
T
P
T
E
R
K
R
Q
G
Y
I
H
E
L
I
V
T
E
E
N
Y
V
N
D
L
Q
L
V
T
E
I
F
Q
K
P
L
M
---
E
SE------
L
L
-----
T
---
E
K
E
V
A
M
I
F
V
N
W
K
E
L
I
M
C
N
I
K
-
L
L
K
A
L
R
V
R
K
--
K
M
S
GE
K
---------
M
-
P
-------------
V
K
M
I
G
D
I
L
S
A
Q
-----
L
P
------
H
------
M
Q
P
Y
I
R
F
C
S
R
Q
L
N
G
A
A
L
I
Q
Q
K
T
D
E
A
P
D
F
K
E
F
V
K
R
L
E
--
M
D
P
R
C
K
G
M
P
L
S
S
F
I
L
K
P
M
Q
R
V
T
R
Y
P
L
I
I
K
N
I
L
E
N
T
P
-
E
N
H
P
D
H
S
H
L
K
H
A
L
E
K
A
E
E
L
C
S
Q
V
N
E
G
V
R
E
K
E
N
S
D
R
L
E
W
--
I
Q
A
H
V
Q
C
E
-
G
LSEQLVFNS---
V
------------
T
--
N
-----------
C
-
L
G
-
P
R
K
F
L
H
S
G
K
L
Y
K
A
K
---------
N
N
K
E
L
Y
G
F
L
F
N
D
F
L
L
L
T
Q
I
---
T
---
K
PKVFSP
K
S
N
-
L
-------------------
Q
Y
M
Y
K
------
T
P
I
F
L
N
E
V
L
V
K
L
P
T
D
P
S
----------
G
D
---
F
-
H
I
S
--------
H
I
D
R
V
Y
T
L
R
A
E
S
I
--
N
E
R
T
A
W
V
Q
K
I
K
A
A
S
E
L
Y
I
E
T
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
52
HHSearch
46.64
23%
54
- C2 -
-
1KZ7
-
C:
[1626-1960]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
S
L
A
I
L
R
R
H
V
M
N
E
L
L
D
T
E
R
A
Y
V
E
E
L
L
C
V
L
E
G
Y
A
A
E
M
D
---
N
--------
P
L
MAHLI
S
T
G
L
Q
N
K
K
N
I
L
F
G
N
M
E
E
I
Y
H
F
H
N
R
I
F
L
R
E
L
E
S
C
I
--
D
----
C
-------------------------
P
E
L
V
G
R
C
F
L
E
R
-----
M
E
------
E
------
F
Q
I
Y
E
K
Y
C
Q
N
K
P
R
S
E
S
L
W
R
Q
C
S
D
-
C
P
F
F
Q
E
C
Q
K
K
L
-------
D
H
K
L
S
L
D
S
Y
L
L
K
P
V
Q
R
I
T
K
Y
Q
L
L
L
K
E
M
L
K
Y
S
K
-
H
-
C
E
G
A
E
D
L
Q
E
A
L
S
S
I
L
G
I
L
K
A
V
N
D
S
M
H
L
I
-------------
A
I
T
G
Y
-
D
------------
G
------------
N
--
L
-----------
G
-
D
L
-
G
K
-
L
L
M
Q
G
S
F
S
V
W
T
D
H
K
ELAR-
F
K
P
M
Q
R
H
L
F
L
H
E
K
A
V
L
F
C
K
K
---
R
---
E
ENGEGYEK
A
-
P
-------------------
S
Y
S
Y
K
------
Q
S
L
N
M
T
A
V
G
I
T
E
N
V
K
G
D
------------
T
K
K
F
-
E
I
W
Y
------
N
A
R
E
E
V
Y
I
I
Q
A
P
T
P
--
E
I
K
A
A
W
V
N
A
I
R
K
V
L
T
S
Q
L
Q
A
C
R
E
A
S
Q
H
R
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
48
HHSearch
46.52
22%
40
- C2 -
-
1FOE
-
TIAM1_MOUSE
E:
[6-372]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
D
A
D
K
L
R
K
V
I
C
E
L
L
E
T
E
R
T
Y
V
K
D
L
N
C
L
M
E
R
Y
L
K
P
L
Q
---
K
ET------
F
L
-----
T
---
Q
D
E
L
D
V
L
F
G
N
L
T
E
M
V
E
F
Q
V
E
-
F
L
K
T
L
E
D
G
V
--
R
----
L
---------
V
P
D
LEKLEKVDQFKKV
L
F
S
L
G
G
S
F
L
Y
Y
-----
A
D
------
R
------
F
K
L
Y
S
A
F
C
A
S
H
T
K
V
P
K
V
L
V
K
-
A
K
T
D
T
A
F
K
A
F
L
D
A
Q
N
--
P
R
Q
-
Q
H
S
S
T
L
E
S
Y
L
I
K
P
I
Q
R
V
L
K
Y
P
L
L
L
R
E
L
F
A
L
T
D
-
A
E
S
E
E
H
Y
H
L
D
V
A
I
K
T
M
N
K
V
A
S
H
I
N
E
M
Q
K
I
H
E
E
F
G
A
V
F
D
QL
I
A
E
Q
T
G
E
K
K
E
------------
V
------------
A
--
D
-----------
L
-
S
M
-
G
D
-
L
L
L
H
T
S
V
I
W
L
N
P
P
A
SLGKW
K
K
E
P
E
L
A
A
F
V
F
K
T
A
V
V
L
V
Y
K
---
D
---
G
----------
S
KQKKKLVGSHRLSIYEEWD
P
F
R
F
R
------
H
M
I
P
T
E
A
L
Q
V
R
A
L
P
S
A
D
A
----------
E
A
N
A
V
C
E
I
V
H
VKSESE
G
R
P
E
R
V
F
H
L
C
C
S
S
P
--
E
S
R
K
D
F
L
K
S
V
H
S
I
L
R
D
K
H
R
R
Q
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
49
HHSearch
46.34
22%
38
- C2 -
-
1FOE
-
TIAM1_MOUSE
A:
[5-372]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
L
S
D
A
D
K
L
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K
V
I
C
E
L
L
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T
E
R
T
Y
V
K
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L
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L
M
E
R
Y
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L
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---
K
ET------
F
L
-----
T
---
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D
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L
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N
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----
L
---------
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LEKLEKVDQF
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L
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------
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--
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------------
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--
D
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L
L
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V
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V
F
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A
V
V
L
V
Y
K
---
D
---
G
----------
S
KQKKKLVGSHRLSIYEEWD
P
F
R
F
R
------
H
M
I
P
T
E
A
L
Q
V
R
A
L
P
S
A
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A
----------
E
A
N
A
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C
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VKSESE
G
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L
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C
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--
E
S
R
K
D
F
L
K
S
V
H
S
I
L
R
D
K
H
R
R
Q
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------