@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : ABI1_HUMAN: (2018-07-12 )
MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLASVAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSRTHKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENISVPPPSGAPPAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESIMHYTD
Atome Classification :
(20 SA)
-.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480......---.490.......500......
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
-
M
A
E
L
Q
M
L
L
E
E
EIPS
G
K
R
A
L
I
E
S
Y
Q
N
L
T
R
V
A
D
Y
C
ENN
Y
I
QA
T
D
K
R
K
A
L
E
E
T
K
A
Y
T
T
Q
S
L
A
S
V
A
Y
Q
I
N
A
L
A
N
N
V
L
Q
L
L
DI
Q
A
S
Q
L
R
R
M
E
S
S
I
N
H
I
S
Q
T
V
D
I
H
K
E
K
V
A
RR
E
I
G
I
L
TTNKNTSR
T
H
K
I
IAPAN
M
E
R
P
V
R
Y
I
RKPI
D
Y
T
V
L
D
DVGH
G
V
K
W
L
K
AKHGNNQPARTGTLSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMT
S
P
A
RLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIG
I
P
I
AVPTPSPPTIGPENISVPPPSGAPPAPPLAPLLP
V
S
T
VIAAPGSAPGSQY
G
T
M
T
R
Q
I
S
RHNSTTSSTSSGGYRRT
P
S
V
T
A
Q
FSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIP
L
T
G
F
V
A
R
V
Q
E
NIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDE
E
A
A
V
V
Q
YNDPYADGDPAWA
P
K
N
Y
I
E
K
V
V
A
I
Y
DYTKDKDDELSFME
G
A
I
I
Y
V
I
KKNDD
G
W
Y
E
G
V
C
---
N
R
V
TGLF
P
G
N
Y
V
E
S
I
M
HYTD
41
Fugue
73.48
89%
-88
- C2 -
-
3P8C
1
ABI2_HUMAN
F:
[1-156]
A
M
A
E
L
Q
M
L
L
E
E
E
I
P
G
G
R
R
A
L
F
D
S
Y
T
N
L
E
R
V
A
D
Y
C
E
N
N
Y
I
Q
S
A
D
K
Q
R
A
L
E
E
T
K
A
Y
T
T
Q
S
L
A
S
V
A
Y
L
I
N
T
L
A
N
N
V
L
Q
M
L
D
I
Q
A
S
Q
L
R
R
M
E
S
S
I
N
H
I
S
Q
T
V
D
I
H
K
E
K
V
A
R
R
E
I
G
I
L
T
T
N
K
N
T
S
R
T
H
K
I
I
A
P
A
N
L
E
R
P
V
R
Y
I
R
K
P
I
D
Y
T
I
L
D
D
I
G
H
G
V
K
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
70.18
89%
-57
* C2 *
-
3P8C
1
ABI2_HUMAN
F:
[2-156]
-
M
A
E
L
Q
M
L
L
E
E
E
I
P
G
G
R
R
A
L
F
D
S
Y
T
N
L
E
R
V
A
D
Y
C
E
N
N
Y
I
Q
S
A
D
K
Q
R
A
L
E
E
T
K
A
Y
T
T
Q
S
L
A
S
V
A
Y
L
I
N
T
L
A
N
N
V
L
Q
M
L
D
I
Q
A
S
Q
L
R
R
M
E
S
S
I
N
H
I
S
Q
T
V
D
I
H
K
E
K
V
A
R
R
E
I
G
I
L
T
T
N
K
N
T
S
R
T
H
K
I
I
A
P
A
N
L
E
R
P
V
R
Y
I
R
K
P
I
D
Y
T
I
L
D
D
I
G
H
G
V
K
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
69.33
89%
-56
- C2 -
-
3P8C
1
ABI2_HUMAN
F:
[2-155]
-
M
A
E
L
Q
M
L
L
E
E
E
I
P
G
G
R
R
A
L
F
D
S
Y
T
N
L
E
R
V
A
D
Y
C
E
N
N
Y
I
Q
S
A
D
K
Q
R
A
L
E
E
T
K
A
Y
T
T
Q
S
L
A
S
V
A
Y
L
I
N
T
L
A
N
N
V
L
Q
M
L
D
I
Q
A
S
Q
L
R
R
M
E
S
S
I
N
H
I
S
Q
T
V
D
I
H
K
E
K
V
A
R
R
E
I
G
I
L
T
T
N
K
N
T
S
R
T
H
K
I
I
A
P
A
N
L
E
R
P
V
R
Y
I
R
K
P
I
D
Y
T
I
L
D
D
I
G
H
G
V
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
63.22
87%
-114
- C1 -
-
2ED0
-
A:
[7-72]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
D
P
P
W
A
P
R
S
Y
L
E
K
V
V
A
I
Y
D
Y
T
K
D
K
E
D
E
L
S
F
Q
E
G
A
I
I
Y
V
I
K
K
N
D
D
G
W
Y
E
G
V
M
---
N
G
V
T
G
L
F
P
G
N
Y
V
E
S
I
-----
1
PsiBlast_PDB
60.96
62%
-39
- C2 -
-
4N78
2
ABI2_HUMAN
F:
[2-156]
-
M
A
E
L
Q
M
L
L
E
E
E
I
P
G
G
R
R
A
L
F
D
S
Y
T
N
L
E
R
V
A
D
Y
C
E
N
N
Y
I
Q
S
A
D
K
Q
R
A
L
E
E
T
K
A
Y
T
T
Q
S
L
A
S
V
A
Y
L
I
N
T
L
A
N
N
V
L
Q
M
L
D
I
Q
A
S
Q
L
R
R
M
E
S
S
I
N
H
I
S
Q
T
V
D
I
H
K
E
K
V
A
R
R
E
I
G
I
L
T
T
N
K
N
T
S
R
T
H
K
I
I
A
P
A
N
L
E
R
P
V
R
Y
I
R
K
P
I
D
Y
T
I
L
D
D
I
G
H
G
V
K
W
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
39
HHSearch
56.02
33%
-138
- C1 -
-
1UTI
-
A:
[3-56]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
A
R
A
L
Y
D
F
E
A
L
E
E
D
E
L
G
F
R
S
G
E
V
V
E
V
L
D
S
S
N
P
S
W
W
T
G
R
L
---
H
N
K
L
G
L
F
P
A
N
Y
V
A
P
M
-----
16
PsiBlast_PDB
55.99
43%
-109
- C1 -
-
2DF6
-
ARHG7_RAT
A:
[7-59]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
R
A
K
F
N
F
Q
Q
T
N
E
D
E
L
S
F
S
K
G
D
V
I
H
V
T
R
V
E
E
G
G
W
W
E
G
T
H
---
N
G
R
T
G
W
F
P
S
N
Y
V
R
E
I
-----
7
PsiBlast_PDB
55.31
54%
-142
- C1 -
-
3ULR
-
B:
[13-62]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
A
L
Y
D
Y
Q
A
A
G
D
D
E
I
S
F
D
P
D
D
I
I
T
N
I
E
M
I
D
D
G
W
W
R
G
V
C
---
K
G
R
Y
G
L
F
P
A
N
Y
V
E
-------
5
PsiBlast_PDB
54.80
56%
-132
- C1 -
-
2D1X
-
SRC8_HUMAN
A:
[14-63]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
A
L
Y
D
Y
Q
A
A
G
D
D
E
I
S
F
D
P
D
D
I
I
T
N
I
E
M
I
D
D
G
W
W
R
G
V
C
---
K
G
R
Y
G
L
F
P
A
N
Y
V
E
-------
4
PsiBlast_PDB
54.28
50%
-125
- C1 -
-
1UDL
-
A:
[34-87]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
C
Q
V
I
A
M
Y
D
Y
A
A
N
N
E
D
E
L
S
F
S
K
G
Q
L
I
N
V
M
N
K
D
D
P
D
W
W
Q
G
E
I
---
N
G
V
T
G
L
F
P
S
N
Y
V
K
-------
43
Fugue
54.01
23%
-60
- C1 -
-
2FPE
1
JIP1_RAT
A:
[1-62]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
S
E
Q
T
H
R
A
I
F
R
F
V
P
R
H
E
D
E
L
E
L
E
V
D
D
P
L
L
V
E
L
Q
A
E
D
Y
W
Y
E
A
Y
N
MR-
T
G
A
R
G
V
F
P
A
Y
Y
A
I
E
V
T
K
---
35
HHSearch
53.12
27%
-125
- C1 -
-
2KYM
-
?
A:
[4-62]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
F
A
V
T
L
Y
E
F
K
A
E
R
D
D
E
L
D
V
S
P
G
E
N
L
S
I
C
A
H
Y
D
Y
E
W
F
I
A
K
P
IN
R
L
G
G
P
G
L
V
P
V
S
Y
V
R
I
I
D
----
12
PsiBlast_PDB
53.10
46%
-116
- C1 -
-
2BZ8
-
SH3K1_HUMAN
A:
[2-56]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
E
A
I
V
E
-
F
D
Y
Q
A
Q
H
D
D
E
L
T
I
S
V
G
E
I
I
T
N
I
R
K
E
D
G
G
W
W
E
G
Q
I
---
N
G
R
R
G
L
F
P
D
N
F
V
R
E
I
-----
27
HHSearch
53.01
45%
-112
- C1 -
-
3JV3
-
ITSN1_MOUSE
A:
[1151-1206]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
C
Q
V
I
G
M
Y
D
Y
T
A
Q
N
D
D
E
L
A
F
S
K
G
Q
I
I
N
V
L
N
K
E
D
P
D
W
W
K
G
E
V
---
S
G
Q
V
G
L
F
P
S
N
Y
V
K
L
T
T
----
17
PsiBlast_PDB
52.69
43%
-117
- C1 -
-
2P4R
1
ARHG7_RAT
A:
[7-59]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
R
A
K
F
N
F
Q
Q
T
N
E
D
E
L
S
F
S
K
G
D
V
I
H
V
T
R
V
E
E
G
G
W
W
E
G
T
H
---
N
G
R
T
G
W
F
P
S
N
Y
V
R
E
I
-----
18
PsiBlast_PDB
52.44
43%
-119
- C1 -
-
2G6F
1
ARHG7_RAT
X:
[7-59]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
R
A
K
F
N
F
Q
Q
T
N
E
D
E
L
S
F
S
K
G
D
V
I
H
V
T
R
V
E
E
G
G
W
W
E
G
T
H
---
N
G
R
T
G
W
F
P
S
N
Y
V
R
E
I
-----
11
PsiBlast_PDB
52.07
41%
-128
- C1 -
-
5SXP
-
ARHG7_HUMAN
A:
[8-60]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
R
A
K
F
N
F
Q
Q
T
N
E
D
E
L
S
F
S
K
G
D
V
I
H
V
T
R
V
E
E
G
G
W
W
E
G
T
L
---
N
G
R
T
G
W
F
P
S
N
Y
V
R
E
V
-----
14
PsiBlast_PDB
52.04
41%
-100
- C1 -
-
1UJ0
-
A:
[7-59]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
V
R
A
L
Y
D
F
E
A
V
E
D
N
E
L
T
F
K
H
G
E
L
I
T
V
L
D
D
S
D
A
N
W
W
Q
G
E
N
---
H
R
G
T
G
L
F
P
S
N
F
V
T
T
------
15
PsiBlast_PDB
51.93
43%
-109
- C1 -
-
2ESW
-
ARHG7_MOUSE
A:
[9-61]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
R
A
K
F
N
F
Q
Q
T
N
E
D
E
L
S
F
S
K
G
D
V
I
H
V
T
R
V
E
E
G
G
W
W
E
G
T
H
---
N
G
R
T
G
W
F
P
S
N
Y
V
R
E
I
-----
36
HHSearch
51.69
33%
-82
- C1 -
-
4U5W
2
HCK_HUMAN
B:
[10-66]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
I
V
V
A
L
Y
D
Y
E
A
I
H
H
E
D
L
S
F
Q
K
G
D
Q
M
V
V
L
E
E
-
S
G
E
W
W
K
A
R
S
LA-
T
R
K
E
G
Y
I
P
S
N
Y
V
A
R
V
-----