@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : ARPC2_HUMAN: (2018-07-12 )
MILLEVNNRIIEETLALKFENAAAGNKPEAVEVTFADFDGVLYHISNPNGDKTKVMVSISLKFYKELQAHGADELLKRVYGSFLVNPESGYNVSLLYDLENLPASKDSIVHQAGMLKRNCFASVFEKYFQFQEEGKEGENRAVIHYRDDETMYVESKKDRVTVVFSTVFKDDDDVVIGKVFMQEFKEGRRASHTAPQVLFSHREPPLELKDTDAAVGDNIGYITFVLFPRHTNASARDNTINLIHTFRDYLHYHIKCSKAYIHTRMRAKTSDFLKVLNRARPDAEKKEMKTITGKTFSSR
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100...---....110.......120.......130.....--------..140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
M
I
L
L
EVN
N
R
I
I
E
E
T
L
A
L
K
F
ENAAAGNKP
E
A
V
E
V
T
F
ADFD
G
V
L
Y
H
ISNPNGD
K
T
K
V
M
V
S
I
S
L
K
F
Y
K
E
L
Q
AH
G
A
D
E
L
L
K
R
V
Y
G
S
F
L
VNPESG
Y
N
V
S
L
L
Y
DLENLPA
S
---
K
D
S
I
V
H
Q
A
G
M
L
K
R
N
C
F
A
S
V
F
E
K
Y
F
Q
F
Q
E
EGKE--------GE
N
R
A
V
I
H
YRDD
E
T
M
Y
V
ESKKD
R
V
T
V
V
F
S
T
VFKDDDD
V
V
I
G
K
V
F
M
Q
E
F
K
EGRRASHT
A
P
Q
V
L
FSHREPPLELKDTDAAVGDN
I
G
Y
I
T
F
V
L
F
PRHTNASARDN
T
I
N
L
I
H
T
F
R
D
Y
L
H
Y
H
I
K
C
S
K
A
Y
I
H
T
R
MRA
K
T
S
D
F
L
K
V
L
N
RARP
D
A
E
K
K
E
M
K
T
ITGKTFSSR
21
HHSearch
85.24
100%
-110
- C5 -
-
1K8K
-
ARPC2_BOVIN
D:
[1-284]
M
I
L
L
E
V
N
N
R
I
I
E
E
T
L
A
L
K
F
E
N
A
A
A
G
N
K
P
E
A
V
E
V
T
F
A
D
F
D
G
V
L
Y
H
I
S
N
P
N
G
D
K
T
K
V
M
V
S
I
S
L
K
F
Y
K
E
L
Q
A
H
G
A
D
E
L
L
K
R
V
Y
G
S
Y
L
V
N
P
E
S
G
Y
N
V
S
L
L
Y
D
L
E
N
L
P
A
S
---
K
D
S
I
V
H
Q
A
G
M
L
K
R
N
C
F
A
S
V
F
E
K
Y
F
Q
F
Q
E
E
G
K
E
--------
G
E
N
R
A
V
I
H
Y
R
D
D
E
T
M
Y
V
E
S
K
K
D
R
V
T
V
V
F
S
T
V
F
K
D
D
D
D
V
V
I
G
K
V
F
M
Q
E
F
K
E
G
R
R
A
S
H
T
A
P
Q
V
L
F
S
H
R
E
P
P
L
E
L
K
D
T
D
A
A
V
G
D
N
I
G
Y
I
T
F
V
L
F
P
R
H
T
N
A
S
A
R
D
N
T
I
N
L
I
H
T
F
R
D
Y
L
H
Y
H
I
K
C
S
K
A
Y
I
H
T
R
M
R
A
K
T
S
D
F
L
K
V
L
N
R
A
R
P
D
A
----------------
1
PsiBlast_PDB
85.04
99%
-110
- C5 -
-
1K8K
-
ARPC2_BOVIN
D:
[1-284]
M
I
L
L
E
V
N
N
R
I
I
E
E
T
L
A
L
K
F
E
N
A
A
A
G
N
K
P
E
A
V
E
V
T
F
A
D
F
D
G
V
L
Y
H
I
S
N
P
N
G
D
K
T
K
V
M
V
S
I
S
L
K
F
Y
K
E
L
Q
A
H
G
A
D
E
L
L
K
R
V
Y
G
S
Y
L
V
N
P
E
S
G
Y
N
V
S
L
L
Y
D
L
E
N
L
P
A
S
---
K
D
S
I
V
H
Q
A
G
M
L
K
R
N
C
F
A
S
V
F
E
K
Y
F
Q
F
Q
E
E
G
K
E
--------
G
E
N
R
A
V
I
H
Y
R
D
D
E
T
M
Y
V
E
S
K
K
D
R
V
T
V
V
F
S
T
V
F
K
D
D
D
D
V
V
I
G
K
V
F
M
Q
E
F
K
E
G
R
R
A
S
H
T
A
P
Q
V
L
F
S
H
R
E
P
P
L
E
L
K
D
T
D
A
A
V
G
D
N
I
G
Y
I
T
F
V
L
F
P
R
H
T
N
A
S
A
R
D
N
T
I
N
L
I
H
T
F
R
D
Y
L
H
Y
H
I
K
C
S
K
A
Y
I
H
T
R
M
R
A
K
T
S
D
F
L
K
V
L
N
R
A
R
P
D
A
----------------
31
Fugue
85.03
99%
-110
- C5 -
-
1K8K
-
ARPC2_BOVIN
D:
[1-283]
M
I
L
L
E
V
N
N
R
I
I
E
E
T
L
A
L
K
F
E
N
A
A
A
G
N
K
P
E
A
V
E
V
T
F
A
D
F
D
G
V
L
Y
H
I
S
N
P
N
G
D
K
T
K
V
M
V
S
I
S
L
K
F
Y
K
E
L
Q
A
H
G
A
D
E
L
L
K
R
V
Y
G
S
Y
L
V
N
P
E
S
G
Y
N
V
S
L
L
Y
D
L
E
N
L
P
A
S
---
K
D
S
I
V
H
Q
A
G
M
L
K
R
N
C
F
A
S
V
F
E
K
Y
F
Q
F
Q
E
E
G
K
E
--------
G
E
N
R
A
V
I
H
Y
R
D
D
E
T
M
Y
V
E
S
K
K
D
R
V
T
V
V
F
S
T
V
F
K
D
D
D
D
V
V
I
G
K
V
F
M
Q
E
F
K
E
G
R
R
A
S
H
T
A
P
Q
V
L
F
S
H
R
E
P
P
L
E
L
K
D
T
D
A
A
V
G
D
N
I
G
Y
I
T
F
V
L
F
P
R
H
T
N
A
S
A
R
D
N
T
I
N
L
I
H
T
F
R
D
Y
L
H
Y
H
I
K
C
S
K
A
Y
I
H
T
R
M
R
A
K
T
S
D
F
L
K
V
L
N
R
A
R
P
D
-----------------
12
PsiBlast_PDB
84.80
99%
-110
- C5 -
-
3UKR
-
ARPC2_BOVIN
D:
[1-282]
M
I
L
L
E
V
N
N
R
I
I
E
E
T
L
A
L
K
F
E
N
A
A
A
G
N
K
P
E
A
V
E
V
T
F
A
D
F
D
G
V
L
Y
H
I
S
N
P
N
G
D
K
T
K
V
M
V
S
I
S
L
K
F
Y
K
E
L
Q
A
H
G
A
D
E
L
L
K
R
V
Y
G
S
Y
L
V
N
P
E
S
G
Y
N
V
S
L
L
Y
D
L
E
N
L
P
A
S
---
K
D
S
I
V
H
Q
A
G
M
L
K
R
N
C
F
A
S
V
F
E
K
Y
F
Q
F
Q
E
E
G
K
E
--------
G
E
N
R
A
V
I
H
Y
R
D
D
E
T
M
Y
V
E
S
K
K
D
R
V
T
V
V
F
S
T
V
F
K
D
D
D
D
V
V
I
G
K
V
F
M
Q
E
F
K
E
G
R
R
A
S
H
T
A
P
Q
V
L
F
S
H
R
E
P
P
L
E
L
K
D
T
D
A
A
V
G
D
N
I
G
Y
I
T
F
V
L
F
P
R
H
T
N
A
S
A
R
D
N
T
I
N
L
I
H
T
F
R
D
Y
L
H
Y
H
I
K
C
S
K
A
Y
I
H
T
R
M
R
A
K
T
S
D
F
L
K
V
L
N
R
A
R
P
------------------
3
PsiBlast_PDB
84.74
99%
-107
- C5 -
-
1U2V
-
ARPC2_BOVIN
D:
[1-282]
M
I
L
L
E
V
N
N
R
I
I
E
E
T
L
A
L
K
F
E
N
A
A
A
G
N
K
P
E
A
V
E
V
T
F
A
D
F
D
G
V
L
Y
H
I
S
N
P
N
G
D
K
T
K
V
M
V
S
I
S
L
K
F
Y
K
E
L
Q
A
H
G
A
D
E
L
L
K
R
V
Y
G
S
Y
L
V
N
P
E
S
G
Y
N
V
S
L
L
Y
D
L
E
N
L
P
A
S
---
K
D
S
I
V
H
Q
A
G
M
L
K
R
N
C
F
A
S
V
F
E
K
Y
F
Q
F
Q
E
E
G
K
E
--------
G
E
N
R
A
V
I
H
Y
R
D
D
E
T
M
Y
V
E
S
K
K
D
R
V
T
V
V
F
S
T
V
F
K
D
D
D
D
V
V
I
G
K
V
F
M
Q
E
F
K
E
G
R
R
A
S
H
T
A
P
Q
V
L
F
S
H
R
E
P
P
L
E
L
K
D
T
D
A
A
V
G
D
N
I
G
Y
I
T
F
V
L
F
P
R
H
T
N
A
S
A
R
D
N
T
I
N
L
I
H
T
F
R
D
Y
L
H
Y
H
I
K
C
S
K
A
Y
I
H
T
R
M
R
A
K
T
S
D
F
L
K
V
L
N
R
A
R
P
------------------
11
PsiBlast_PDB
84.24
99%
-108
- C5 -
-
3DXM
-
ARPC2_BOVIN
D:
[1-282]
M
I
L
L
E
V
N
N
R
I
I
E
E
T
L
A
L
K
F
E
N
A
A
A
G
N
K
P
E
A
V
E
V
T
F
A
D
F
D
G
V
L
Y
H
I
S
N
P
N
G
D
K
T
K
V
M
V
S
I
S
L
K
F
Y
K
E
L
Q
A
H
G
A
D
E
L
L
K
R
V
Y
G
S
Y
L
V
N
P
E
S
G
Y
N
V
S
L
L
Y
D
L
E
N
L
P
A
S
---
K
D
S
I
V
H
Q
A
G
M
L
K
R
N
C
F
A
S
V
F
E
K
Y
F
Q
F
Q
E
E
G
K
E
--------
G
E
N
R
A
V
I
H
Y
R
D
D
E
T
M
Y
V
E
S
K
K
D
R
V
T
V
V
F
S
T
V
F
K
D
D
D
D
V
V
I
G
K
V
F
M
Q
E
F
K
E
G
R
R
A
S
H
T
A
P
Q
V
L
F
S
H
R
E
P
P
L
E
L
K
-
T
D
A
A
V
G
D
N
I
G
Y
I
T
F
V
L
F
P
R
H
T
N
A
S
A
R
D
N
T
I
N
L
I
H
T
F
R
D
Y
L
H
Y
H
I
K
C
S
K
A
Y
I
H
T
R
M
R
A
K
T
S
D
F
L
K
V
L
N
R
A
R
P
------------------
10
PsiBlast_PDB
84.12
99%
-110
- C5 -
-
3DXK
-
ARPC2_BOVIN
D:
[1-282]
M
I
L
L
E
V
N
N
R
I
I
E
E
T
L
A
L
K
F
E
N
A
A
A
G
N
K
P
E
A
V
E
V
T
F
A
D
F
D
G
V
L
Y
H
I
S
N
P
N
G
D
K
T
K
V
M
V
S
I
S
L
K
F
Y
K
E
L
Q
A
H
G
A
D
E
L
L
K
R
V
Y
G
S
Y
L
V
N
P
E
S
G
Y
N
V
S
L
L
Y
D
L
E
N
L
P
A
S
---
K
D
S
I
V
H
Q
A
G
M
L
K
R
N
C
F
A
S
V
F
E
K
Y
F
Q
F
Q
E
E
G
K
E
--------
G
E
N
R
A
V
I
H
Y
R
D
D
E
T
M
Y
V
E
S
K
K
D
R
V
T
V
V
F
S
T
V
F
K
D
D
D
D
V
V
I
G
K
V
F
M
Q
E
F
K
E
G
R
R
A
S
H
T
A
P
Q
V
L
F
S
H
R
E
P
P
L
E
L
K
D
T
D
A
A
V
G
D
N
I
G
Y
I
T
F
V
L
F
P
R
H
T
N
A
S
A
R
D
N
T
I
N
L
I
H
T
F
R
D
Y
L
H
Y
H
I
K
C
S
K
A
Y
I
H
T
R
M
R
A
K
T
S
D
F
L
K
V
L
N
R
A
R
P
------------------
14
PsiBlast_PDB
84.04
99%
-104
- C5 -
-
3ULE
-
ARPC2_BOVIN
D:
[1-282]
M
I
L
L
E
V
N
N
R
I
I
E
E
T
L
A
L
K
F
E
N
A
A
A
G
N
K
P
E
A
V
E
V
T
F
A
D
F
D
G
V
L
Y
H
I
S
N
P
N
G
D
K
T
K
V
M
V
S
I
S
L
K
F
Y
K
E
L
Q
A
H
G
A
D
E
L
L
K
R
V
Y
G
S
Y
L
V
N
P
E
S
G
Y
N
V
S
L
L
Y
D
L
E
N
L
P
A
S
---
K
D
S
I
V
H
Q
A
G
M
L
K
R
N
C
F
A
S
V
F
E
K
Y
F
Q
F
Q
E
E
G
K
E
--------
G
E
N
R
A
V
I
H
Y
R
D
D
E
T
M
Y
V
E
S
K
K
D
R
V
T
V
V
F
S
T
V
F
K
D
D
D
D
V
V
I
G
K
V
F
M
Q
E
F
K
E
G
R
R
A
S
H
T
A
P
Q
V
L
F
S
H
R
E
P
P
L
E
L
K
-
T
D
A
A
V
G
D
N
I
G
Y
I
T
F
V
L
F
P
R
H
T
N
A
S
A
R
D
N
T
I
N
L
I
H
T
F
R
D
Y
L
H
Y
H
I
K
C
S
K
A
Y
I
H
T
R
M
R
A
K
T
S
D
F
L
K
V
L
N
R
A
R
P
------------------
15
PsiBlast_PDB
83.88
99%
-98
- C5 -
-
4JD2
-
ARPC2_BOVIN
D:
[1-283]
M
I
L
L
E
V
N
N
R
I
I
E
E
T
L
A
L
K
F
E
N
A
A
A
G
N
K
P
E
A
V
E
V
T
F
A
D
F
D
G
V
L
Y
H
I
S
N
P
N
G
D
K
T
K
V
M
V
S
I
S
L
K
F
Y
K
E
L
Q
A
H
G
A
D
E
L
L
K
R
V
Y
G
S
Y
L
V
N
P
E
S
G
Y
N
V
S
L
L
Y
D
L
E
N
L
P
A
S
---
K
D
S
I
V
H
Q
A
G
M
L
K
R
N
C
F
A
S
V
F
E
K
Y
F
Q
F
Q
E
E
G
K
E
--------
G
E
N
R
A
V
I
H
Y
R
D
D
E
T
M
Y
V
E
S
K
K
D
R
V
T
V
V
F
S
T
V
F
K
D
D
D
D
V
V
I
G
K
V
F
M
Q
E
F
K
E
G
R
R
A
S
H
T
A
P
Q
V
L
F
S
H
R
E
P
P
L
E
L
K
D
T
D
A
A
V
G
D
N
I
G
Y
I
T
F
V
L
F
P
R
H
T
N
A
S
A
R
D
N
T
I
N
L
I
H
T
F
R
D
Y
L
H
Y
H
I
K
C
S
K
A
Y
I
H
T
R
M
R
A
K
T
S
D
F
L
K
V
L
N
R
A
R
P
D
-----------------
9
PsiBlast_PDB
83.77
99%
-110
- C5 -
-
2P9U
-
ARPC2_BOVIN
D:
[1-282]
M
I
L
L
E
V
N
N
R
I
I
E
E
T
L
A
L
K
F
E
N
A
A
A
G
N
K
P
E
A
V
E
V
T
F
A
D
F
D
G
V
L
Y
H
I
S
N
P
N
G
D
K
T
K
V
M
V
S
I
S
L
K
F
Y
K
E
L
Q
A
H
G
A
D
E
L
L
K
R
V
Y
G
S
Y
L
V
N
P
E
S
G
Y
N
V
S
L
L
Y
D
L
E
N
L
P
A
S
---
K
D
S
I
V
H
Q
A
G
M
L
K
R
N
C
F
A
S
V
F
E
K
Y
F
Q
F
Q
E
E
G
K
E
--------
G
E
N
R
A
V
I
H
Y
R
D
D
E
T
M
Y
V
E
S
K
K
D
R
V
T
V
V
F
S
T
V
F
K
D
D
D
D
V
V
I
G
K
V
F
M
Q
E
F
K
E
G
R
R
A
S
H
T
A
P
Q
V
L
F
S
H
R
E
P
P
L
E
L
--
T
D
A
A
V
G
D
N
I
G
Y
I
T
F
V
L
F
P
R
H
T
N
A
S
A
R
D
N
T
I
N
L
I
H
T
F
R
D
Y
L
H
Y
H
I
K
C
S
K
A
Y
I
H
T
R
M
R
A
K
T
S
D
F
L
K
V
L
N
R
A
R
P
------------------
7
PsiBlast_PDB
83.35
99%
-109
- C5 -
-
2P9N
-
ARPC2_BOVIN
D:
[1-283]
M
I
L
L
E
V
N
N
R
I
I
E
E
T
L
A
L
K
F
E
N
A
A
A
G
N
K
P
E
A
V
E
V
T
F
A
D
F
D
G
V
L
Y
H
I
S
N
P
N
G
D
K
T
K
V
M
V
S
I
S
L
K
F
Y
K
E
L
Q
A
H
G
A
D
E
L
L
K
R
V
Y
G
S
Y
L
V
N
P
E
S
G
Y
N
V
S
L
L
Y
D
L
E
N
L
P
A
S
---
K
D
S
I
V
H
Q
A
G
M
L
K
R
N
C
F
A
S
V
F
E
K
Y
F
Q
F
Q
E
E
G
K
E
--------
G
E
N
R
A
V
I
H
Y
R
D
D
E
T
M
Y
V
E
S
K
K
D
R
V
T
V
V
F
S
T
V
F
K
D
D
D
D
V
V
I
G
K
V
F
M
Q
E
F
K
E
G
R
R
A
S
H
T
A
P
Q
V
L
F
S
H
R
E
P
P
L
E
L
K
D
T
D
A
A
V
G
D
N
I
G
Y
I
T
F
V
L
F
P
R
H
T
N
A
S
A
R
D
N
T
I
N
L
I
H
T
F
R
D
Y
L
H
Y
H
I
K
C
S
K
A
Y
I
H
T
R
M
R
A
K
T
S
D
F
L
K
V
L
N
R
A
R
P
D
-----------------
5
PsiBlast_PDB
83.18
99%
-110
- C5 -
-
2P9K
-
ARPC2_BOVIN
D:
[1-282]
M
I
L
L
E
V
N
N
R
I
I
E
E
T
L
A
L
K
F
E
N
A
A
A
G
N
K
P
E
A
V
E
V
T
F
A
D
F
D
G
V
L
Y
H
I
S
N
P
N
G
D
K
T
K
V
M
V
S
I
S
L
K
F
Y
K
E
L
Q
A
H
G
A
D
E
L
L
K
R
V
Y
G
S
Y
L
V
N
P
E
S
G
Y
N
V
S
L
L
Y
D
L
E
N
L
P
A
S
---
K
D
S
I
V
H
Q
A
G
M
L
K
R
N
C
F
A
S
V
F
E
K
Y
F
Q
F
Q
E
E
G
K
E
--------
G
E
N
R
A
V
I
H
Y
R
D
D
E
T
M
Y
V
E
S
K
K
D
R
V
T
V
V
F
S
T
V
F
K
D
D
D
D
V
V
I
G
K
V
F
M
Q
E
F
K
E
G
R
R
A
S
H
T
A
P
Q
V
L
F
S
H
R
E
P
P
-----
T
D
A
A
V
G
D
N
I
G
Y
I
T
F
V
L
F
P
R
H
T
N
A
S
A
R
D
N
T
I
N
L
I
H
T
F
R
D
Y
L
H
Y
H
I
K
C
S
K
A
Y
I
H
T
R
M
R
A
K
T
S
D
F
L
K
V
L
N
R
A
R
P
------------------
4
PsiBlast_PDB
83.08
99%
-110
- C5 -
-
2P9I
-
ARPC2_BOVIN
D:
[1-283]
M
I
L
L
E
V
N
N
R
I
I
E
E
T
L
A
L
K
F
E
N
A
A
A
G
N
K
P
E
A
V
E
V
T
F
A
D
F
D
G
V
L
Y
H
I
S
N
P
N
G
D
K
T
K
V
M
V
S
I
S
L
K
F
Y
K
E
L
Q
A
H
G
A
D
E
L
L
K
R
V
Y
G
S
Y
L
V
N
P
E
S
G
Y
N
V
S
L
L
Y
D
L
E
N
L
P
A
S
---
K
D
S
I
V
H
Q
A
G
M
L
K
R
N
C
F
A
S
V
F
E
K
Y
F
Q
F
Q
E
E
G
K
E
--------
G
E
N
R
A
V
I
H
Y
R
D
D
E
T
M
Y
V
E
S
K
K
D
R
V
T
V
V
F
S
T
V
F
K
D
D
D
D
V
V
I
G
K
V
F
M
Q
E
F
K
E
G
R
R
A
S
H
T
A
P
Q
V
L
F
S
H
R
E
P
P
L
E
L
---
D
A
A
V
G
D
N
I
G
Y
I
T
F
V
L
F
P
R
H
T
N
A
S
A
R
D
N
T
I
N
L
I
H
T
F
R
D
Y
L
H
Y
H
I
K
C
S
K
A
Y
I
H
T
R
M
R
A
K
T
S
D
F
L
K
V
L
N
R
A
R
P
D
-----------------
6
PsiBlast_PDB
83.01
99%
-112
- C5 -
-
2P9L
-
ARPC2_BOVIN
D:
[1-282]
M
I
L
L
E
V
N
N
R
I
I
E
E
T
L
A
L
K
F
E
N
A
A
A
G
N
K
P
E
A
V
E
V
T
F
A
D
F
D
G
V
L
Y
H
I
S
N
P
N
G
D
K
T
K
V
M
V
S
I
S
L
K
F
Y
K
E
L
Q
A
H
G
A
D
E
L
L
K
R
V
Y
G
S
Y
L
V
N
P
E
S
G
Y
N
V
S
L
L
Y
D
L
E
N
L
P
A
S
---
K
D
S
I
V
H
Q
A
G
M
L
K
R
N
C
F
A
S
V
F
E
K
Y
F
Q
F
Q
E
E
G
K
E
--------
G
E
N
R
A
V
I
H
Y
R
D
D
E
T
M
Y
V
E
S
K
K
D
R
V
T
V
V
F
S
T
V
F
K
D
D
D
D
V
V
I
G
K
V
F
M
Q
E
F
K
E
G
R
R
A
S
H
T
A
P
Q
V
L
F
S
H
R
E
P
P
-----
T
D
A
A
V
G
D
N
I
G
Y
I
T
F
V
L
F
P
R
H
T
N
A
S
A
R
D
N
T
I
N
L
I
H
T
F
R
D
Y
L
H
Y
H
I
K
C
S
K
A
Y
I
H
T
R
M
R
A
K
T
S
D
F
L
K
V
L
N
R
A
R
P
------------------
2
PsiBlast_PDB
82.47
99%
-107
- C5 -
-
1TYQ
-
ARPC2_BOVIN
D:
[1-282]
M
I
L
L
E
V
N
N
R
I
I
E
E
T
L
A
L
K
F
E
N
A
A
A
G
N
K
P
E
A
V
E
V
T
F
A
D
F
D
G
V
L
Y
H
I
S
N
P
N
G
D
K
T
K
V
M
V
S
I
S
L
K
F
Y
K
E
L
Q
A
H
G
A
D
E
L
L
K
R
V
Y
G
S
Y
L
V
N
P
E
S
G
Y
N
V
S
L
L
Y
D
L
E
N
L
P
A
S
---
K
D
S
I
V
H
Q
A
G
M
L
K
R
N
C
F
A
S
V
F
E
K
Y
F
Q
F
Q
E
E
G
K
E
--------
G
E
N
R
A
V
I
H
Y
R
D
D
E
T
M
Y
V
E
S
K
K
D
R
V
T
V
V
F
S
T
V
F
K
D
D
D
D
V
V
I
G
K
V
F
M
Q
E
F
K
E
G
R
R
A
S
H
T
A
P
Q
V
L
F
S
H
R
E
P
P
L
E
--------
G
D
N
I
G
Y
I
T
F
V
L
F
P
R
H
T
N
A
S
A
R
D
N
T
I
N
L
I
H
T
F
R
D
Y
L
H
Y
H
I
K
C
S
K
A
Y
I
H
T
R
M
R
A
K
T
S
D
F
L
K
V
L
N
R
A
R
P
------------------
8
PsiBlast_PDB
82.44
99%
-118
- C5 -
-
2P9P
-
ARPC2_BOVIN
D:
[1-283]
M
I
L
L
E
V
N
N
R
I
I
E
E
T
L
A
L
K
F
E
N
A
A
A
G
N
K
P
E
A
V
E
V
T
F
A
D
F
D
G
V
L
Y
H
I
S
N
P
N
G
D
K
T
K
V
M
V
S
I
S
L
K
F
Y
K
E
L
Q
A
H
G
A
D
E
L
L
K
R
V
Y
G
S
Y
L
V
N
P
E
S
G
Y
N
V
S
L
L
Y
D
L
E
N
L
P
A
S
---
K
D
S
I
V
H
Q
A
G
M
L
K
R
N
C
F
A
S
V
F
E
K
Y
F
Q
F
Q
E
E
G
K
E
--------
G
E
N
R
A
V
I
H
Y
R
D
D
E
T
M
Y
V
E
S
K
K
D
R
V
T
V
V
F
S
T
V
F
K
D
D
D
D
V
V
I
G
K
V
F
M
Q
E
F
K
E
G
R
R
A
S
H
T
A
P
Q
V
L
F
S
H
R
E
P
P
----------
G
D
N
I
G
Y
I
T
F
V
L
F
P
R
H
T
N
A
S
A
R
D
N
T
I
N
L
I
H
T
F
R
D
Y
L
H
Y
H
I
K
C
S
K
A
Y
I
H
T
R
M
R
A
K
T
S
D
F
L
K
V
L
N
R
A
R
P
D
-----------------
13
PsiBlast_PDB
82.15
99%
-113
- C5 -
-
3UKU
-
ARPC2_BOVIN
D:
[1-282]
M
I
L
L
E
V
N
N
R
I
I
E
E
T
L
A
L
K
F
E
N
A
A
A
G
N
K
P
E
A
V
E
V
T
F
A
D
F
D
G
V
L
Y
H
I
S
N
P
N
G
D
K
T
K
V
M
V
S
I
S
L
K
F
Y
K
E
L
Q
A
H
G
A
D
E
L
L
K
R
V
Y
G
S
Y
L
V
N
P
E
S
G
Y
N
V
S
L
L
Y
D
L
E
N
L
P
A
S
---
K
D
S
I
V
H
Q
A
G
M
L
K
R
N
C
F
A
S
V
F
E
K
Y
F
Q
F
Q
E
E
G
K
E
--------
G
E
N
R
A
V
I
H
Y
R
D
D
E
T
M
Y
V
E
S
K
K
D
R
V
T
V
V
F
S
T
V
F
K
D
D
D
D
V
V
I
G
K
V
F
M
Q
E
F
K
E
G
R
R
A
S
H
T
A
P
Q
V
L
F
S
H
R
E
P
P
-----
T
D
A
A
V
G
D
N
I
G
Y
I
T
F
V
L
F
P
R
H
T
N
A
S
A
R
D
N
T
I
N
L
I
H
T
F
R
D
Y
L
H
Y
H
I
K
C
S
K
A
Y
I
H
T
R
M
R
A
K
T
S
D
F
L
K
V
L
N
R
A
R
P
------------------
16
PsiBlast_PDB
81.39
99%
-112
- C5 -
-
4XEI
-
ARPC2_BOVIN
D:
[1-282]
M
I
L
L
E
V
N
N
R
I
I
E
E
T
L
A
L
K
F
E
N
A
A
A
G
N
K
P
E
A
V
E
V
T
F
A
D
F
D
G
V
L
Y
H
I
S
N
P
N
G
D
K
T
K
V
M
V
S
I
S
L
K
F
Y
K
E
L
Q
A
H
G
A
D
E
L
L
K
R
V
Y
G
S
Y
L
V
N
P
E
S
G
Y
N
V
S
L
L
Y
D
L
E
N
L
P
A
S
---
K
D
S
I
V
H
Q
A
G
M
L
K
R
N
C
F
A
S
V
F
E
K
Y
F
Q
F
Q
E
E
G
K
E
--------
G
E
N
R
A
V
I
H
Y
R
D
D
E
T
M
Y
V
E
S
K
K
D
R
V
T
V
V
F
S
T
V
F
K
D
D
D
D
V
V
I
G
K
V
F
M
Q
E
F
K
E
G
R
R
A
S
H
T
A
P
Q
V
L
F
S
H
R
E
P
P
L
E
L
K
D
T
D
A
A
V
G
D
N
I
G
Y
I
T
F
V
L
F
P
R
H
T
N
A
S
A
R
D
N
T
I
N
L
I
H
T
F
R
D
Y
L
H
Y
H
I
K
C
S
K
A
Y
I
H
T
R
M
R
A
K
T
S
D
F
L
K
V
L
N
R
A
R
P
------------------
17
PsiBlast_PDB
78.60
99%
-98
- C5 -
-
4XF2
-
ARPC2_BOVIN
D:
[1-284]
M
I
L
L
E
V
N
N
R
I
I
E
E
T
L
A
L
K
F
E
N
A
A
A
G
N
K
P
E
A
V
E
V
T
F
A
D
F
D
G
V
L
Y
H
I
S
N
P
N
G
D
K
T
K
V
M
V
S
I
S
L
K
F
Y
K
E
L
Q
A
H
G
A
D
E
L
L
K
R
V
Y
G
S
Y
L
V
N
P
E
S
G
Y
N
V
S
L
L
Y
D
L
E
N
L
P
A
S
---
K
D
S
I
V
H
Q
A
G
M
L
K
R
N
C
F
A
S
V
F
E
K
Y
F
Q
F
Q
E
E
G
K
E
--------
G
E
N
R
A
V
I
H
Y
R
D
D
E
T
M
Y
V
E
S
K
K
D
R
V
T
V
V
F
S
T
V
F
K
D
D
D
D
V
V
I
G
K
V
F
M
Q
E
F
K
E
G
R
R
A
S
H
T
A
P
Q
V
L
F
S
H
R
E
P
P
L
E
L
K
D
T
D
A
A
V
G
D
N
I
G
Y
I
T
F
V
L
F
P
R
H
T
N
A
S
A
R
D
N
T
I
N
L
I
H
T
F
R
D
Y
L
H
Y
H
I
K
C
S
K
A
Y
I
H
T
R
M
R
A
K
T
S
D
F
L
K
V
L
N
R
A
R
P
D
A
----------------
22
HHSearch
62.69
48%
-67
* C5 *
-
3DWL
-
ARPC2_SCHPO
I:
[1-303]
M
L
S
L
D
Y
N
N
I
F
I
Y
E
L
L
T
E
R
F
S
----
S
E
N
-----
Q
V
V
T
D
F
D
G
V
T
F
H
I
S
-
T
P
---
T
K
I
L
I
S
L
S
M
K
C
Y
P
E
L
V
N
Y
G
T
L
D
L
L
K
Q
I
Y
G
A
Y
V
H
E
P
E
M
G
Y
N
F
S
I
L
I
D
L
Q
Q
L
P
A
-DEE
K
E
Q
L
A
M
S
I
S
M
L
K
R
N
V
L
A
A
P
F
H
R
A
F
T
K
Q
A
E
L
A
-PMLDKQAT
S
Q
E
L
M
A
I
H
Y
R
D
E
E
T
I
V
L
W
P
E
H
D
R
V
T
V
V
F
S
T
K
F
R
E
E
T
D
R
I
F
G
K
V
F
L
Q
E
F
V
D
A
R
R
---
T
A
P
Q
V
L
F
S
Y
R
D
P
P
L
E
I
R
D
I
Q
------
F
G
F
V
T
F
V
L
F
E
R
H
F
T
P
Q
N
R
E
D
C
I
S
H
I
Q
V
F
R
N
T
L
H
F
H
I
K
A
S
K
A
Y
M
H
Q
R
M
R
K
R
V
A
D
F
Q
K
V
L
N
R
A
K
P
D
V
E
---------------