@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : CCD33_HUMAN: (2018-07-12 )
MAFRGPEPWVSASLLRQRLKAEEKTLDLEFEVLSVGFNEAGRYALRLSAENPLQVGSGAGVQLQVNDGDPFPACSAITDVIEQQEPGQSLTLTRSKFIFTLPKGFCKNDGQHDAQLHVEALRLDEPLGRAAQRVGEAIFPIYPRPDQPRMNPKAQDHEDLYRYCGNLALLRASTDPTARHCGSLAYSVAFHVHRGPQPPVSDSPPRAGQPELMSPEEPLIASQSTEPEIGHLSPSKKETIMVTLHGATNLPACKDGSEPWPYVVVKSTSEEKNNQSSKAVTSVTSEPTRAPIWGDTVNVEIQAEDAGQEDVILKVVDNRKKQELLSYKIPIKYLRVFHPYHFELVKPTESGKADEATAKTQLYATVVRKSSFIPRYIGCNHMALEIFLRGVNEPLANNPNPIVVIARVVPNYKEFKVSQANRDLASVGLPITPLSFPIPSMMNFDVPRVSQNGCPQLSKPGGPPEQPLWNQSFLFQGRDGATSFSEDTALVLEYYSSTSMKGSQPWTLNQPLGISVLPLKSRLYQKMLTGKGLDGLHVERLPIMDTSLKTINDEAPTVALSFQLLSSERPENFLTPNNSKALPTLDPKILDKKLRTIQESWSKDTVSSTMDLSTSTPREAEEEPLVPEMSHDTEMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTVSMKQKLLLSELDMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMKALEETVRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQGKPYTGFPMLSASGLPLGSMGENLPVELYSVLLAENAKLRTELDKNRHQQAPIILQQQALPDLLSGTSDKFNLLAKLEHAQSRILSLESQLEDSARRWGREKQDLATRLQEQEKGFRHPSNSIIIEQPSALTHSMDLKQPSELEPLLPSSDSKLNKPLSPQKETANSQQT
Atome Classification :
(20 SA)
--------........-.10........20........30.---.......40........50......-----------..60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220....-...230.......----240.......250...-------....260.------......270.......280..--.....290.....------..-300.-.....-..310.......---320---.....--....330...--....---.340.......350.......---360.......370.......380.......390.......400...----....410.......420.......430....-...440.......450.......460.......470.......480....----...490-------.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640...------....650.......660....--...670.......680.......690.......700-........710.......720.......730.......740..-....-.750.......760.......770.......780.....----..790.......800.......810.......820.......830.......840.......850.......860.......870.......880.......890.......900.......910.......920.......930.......940.......950......
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
--------MAFRGPEP-
W
V
S
A
S
L
L
R
Q
R
LKAEEKTL
D
L
E
F
E
V
---
L
SVGFNEA
G
R
Y
A
L
R
LSAENPLQVGS-----------GA
G
V
Q
L
Q
VNDGDPFP
A
C
S
A
I
T
D
V
I
E
QQEPGQ
S
L
T
L
T
R
S
K
F
I
F
TLP
K
G
F
CKNDGQH
D
A
Q
L
H
V
E
A
L
RLDE
P
L
G
R
A
A
Q
R
V
G
E
A
I
F
PIYPRPDQPRMNPKAQ
D
H
E
D
L
Y
R
Y
CGN
L
A
L
L
RAST
D
P
T
A
R
H
C
G
S
L
A
Y
S
V
A
F
H
VHRGPQPPVSDSPPRAGQPELMSPEEPLIASQSTE-PEIGHLSPSKK
E
T
----
I
M
V
T
LHGATNLPACKD-------GSEPW
P
Y
V
------
V
V
KSTSEEKNNQSSK
A
V
T
SVT--SEPTRAPIWG
D
T
V
------
N
V
-
E
-
I
Q
-AEDAG-QE
D
V
I
L
K
VVDN
R
---
K
-----
K
Q
E
L
L
--SYKI
P
-
I
K
Y
L
--
R
V
FH---P
Y
H
F
E
L
VKPTESGKADEAT
A
K
---
T
Q
L
Y
A
T
V
V
R
KSSFIP
R
Y
IGC
N
H
M
A
L
E
I
F
L
R
GVNEPLANNPN
P
I
V
V
I
----
A
RVVP
N
Y
K
E
F
KVSQANR
D
L
A
SVGLPITPLSF-PIPSMMNFDVPRVSQNGCPQLSKPGGPPEQPLWNQS
F
L
F
QGRDGATSFSE----D
T
A
L
V
L
-------
E
YYSSTSMKGSQPWTLNQPL
G
I
S
V
L
P
L
K
S
R
L
Y
Q
K
M
L
TGKGLDG
L
H
V
ERLPIMDTSLKTINDEA
P
T
V
A
L
S
F
Q
LLSSERPENFLTPNNSKALPTL
D
P
K
I
L
D
K
K
L
R
T
I
Q
E
SWSKDTVSSTMDLSTSTPREAEEEPLVPEMSHDT
E
M
N
N
Y
R
R
A
M
Q
K
M
------
A
E
D
I
L
S
L
R
R
Q
A
S
I
LEG
E
N
R
I
L
--
R
S
R
L
A
Q
Q
E
E
EEGQGK
A
S
E
A
Q
N
T
V
S
M
K
Q
K
L
L
L
S
EL
D
--
M
K
K
L
R
D
R
V
Q
H
L
Q
N
E
L
I
RKNDRE
K
E
L
L
L
L
Y
QAQQ
P
Q
A
A
L
L
K
Q
Y
Q
-
G
K
L
Q
-
K
M
K
A
L
E
E
T
V
R
H
Q
E
K
V
I
E
K
M
E
R
V
L
E
D
R
L
QDRSKPPPLNRQ----QGKPYTGFPMLSASGLPLGSMGEN
L
P
V
E
L
Y
S
V
L
L
AENA
K
L
R
T
E
L
DKNRHQQA
P
I
I
L
Q
Q
QA
L
P
D
L
LSGT
S
D
K
F
N
L
L
A
K
L
E
H
A
Q
S
R
I
L
S
L
E
S
Q
L
E
D
S
A
R
RWG
R
E
K
Q
D
L
A
T
R
L
Q
E
Q
E
KGFRHPSN
S
I
I
I
EQPSALTHSMDLKQPSELEPLLPSSDSKLNKPLSPQKETANSQQT
27
HHSearch
57.72
20%
-62
- C3 -
-
3HN8
-
SYT3_RAT
B:
[18-116]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
G
S
D
Q
----
L
V
V
R
I
L
Q
A
L
D
L
P
A
K
D
S
-------
N
G
F
S
D
P
Y
V
------
K
I
Y
L
L
P
D
R
K
K
K
F
----
Q
T
K
V
---
H
R
K
T
L
N
P
I
F
N
E
T
F
------
Q
F
-
S
-
V
P
-
L
A
E
L
A
-
Q
R
K
L
H
F
S
V
Y
D
F
D
---
R
FSR--
H
D
L
I
G
--
Q
V
V
L
D
N
L
L
E
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
41
Fugue
56.60
14%
36
- C2 -
-
2DFS
-
MYO5A_CHICK
A:
[5-1080]
ELYTKY
A
R
V
W
I
P
D
P
E
E
V
W
K
S
A
E
L
L
K
D
Y
-
K
P
G
D
K
V
L
Q
L
R
L
E
E
G
K
D
L
E
Y
C
L
D
P
K
T
K
E
L
P
P
L
R
N
P
D
I
L
V
G
E
N
DLTALSYLH
E
P
A
V
L
H
N
L
K
V
R
F
I
D
S
K
L
I
Y
T
Y
C
G
I
V
L
V
A
I
N
P
Y
E
Q
L
P
I
Y
G
E
D
I
I
N
A
Y
S
G
---
Q
N
M
G
D
M
D
P
H
I
F
A
V
A
E
E
A
Y
K
Q
M
A
R
D
E
R
N
Q
S
I
I
V
S
G
-------
E
S
G
A
G
K
T
V
S
A
K
Y
A
M
R
Y
F
A
T
V
S
G
S
A
S
E
A
N
V
E
E
K
V
L
A
S
N
P
I
M
E
S
I
G
N
A
K
T
T
R
N
D
N
S
S
R
F
G
K
Y
I
E
I
G
F
D
K
R
Y
R
I
I
G
A
N
M
R
T
Y
L
L
E
K
S
R
V
V
F
Q
A
E
E
E
RNY
H
I
F
Y
Q
L
C
A
S
A
A
L
P
E
F
K
T
LRLG---
N
A
N
Y
F
H
Y
T
KQGGSP
V
I
D
G
I
D
D
A
K
E
M
V
N
T
R
Q
A
C
T
L
L
GI
S
D
S
Y
Q
M
G
I
F
R
I
L
A
G
I
L
H
L
G
N
V
-
E
-
F
A
-
S
R
D
S
D
-
S
C
A
I
P
P
K
H
D
P
L
T
---
I
-----
F
C
D
L
M
GV
D
Y
E
E
M
-
A
H
W
L
C
-
H
R
K
L
---
A
T
Y
I
K
P
I
S
K
L
H
A
I
N
A
R
D
A
L
A
K
H
I
Y
A
N
L
F
N
W
I
V
D
H
V
N
K
A
L
H
S
T
V
K
Q
H
S
F
I
G
V
L
D
I
Y
G
F
E
T
F
E
I
N
S
F
E
Q
F
C
I
N
Y
A
N
E
K
L
Q
Q
Q
F
N
M
H
V
F
K
L
E
Q
E
E
Y
M
K
E
Q
I
P
W
T
L
I
D
F
Y
D
N
Q
P
C
I
N
L
I
E
A
K
M
G
V
L
D
L
L
D
E
E
C
K
M
P
K
G
S
D
D
T
W
A
Q
K
L
Y
N
T
H
L
N
K
C
A
L
F
E
K
P
RLS
N
K
A
F
I
I
KHFA
D
K
V
E
Y
Q
C
E
G
F
L
E
K
N
K
D
T
V
Y
E
E
Q
I
K
V
L
K
S
S
K
K
F
K
L
L
P
E
L
F
Q
H
K
K
T
V
G
H
Q
F
R
N
S
--
L
H
L
L
M
E
T
L
N
A
T
T
P
H
Y
V
R
C
I
K
P
N
D
F
K
F
P
F
T
F
---
D
E
K
R
A
V
Q
Q
L
R
A
C
G
V
L
E
T
I
R
I
S
A
A
G
F
P
----------
S
R
W
T
Y
Q
E
F
F
S
R
Y
R
V
L
-
M
K
Q
K
D
V
L
S
D
R
K
Q
T
C
K
N
V
------
L
E
K
L
I
L
D
K
D
K
Y
Q
F
--
G
K
T
K
I
F
F
R
A
G
Q
V
A
Y
L
E
K
I
R
A
D
K
L
R
A
A
C
I
R
I
Q
K
T
I
R
G
W
L
M
R
K
K
Y
--
M
R
M
R
R
A
A
I
T
I
Q
R
Y
V
R
G
H
Q
A
R
C
Y
A
T
F
L
R
R
T
R
A
A
I
I
I
Q
K
F
Q
R
M
Y
V
-
V
R
K
R
-
Y
Q
C
M
R
D
A
T
I
A
L
Q
A
L
L
R
G
Y
L
V
R
N
K
Y
Q
M
M
L
R
E
H
K
S
I
I
I
Q
K
H
V
R
GW
L
A
R
V
H
Y
H
R
T
L
K
A
I
V
Y
L
Q
C
C
Y
R
R
M
M
A
K
R
E
L
K
K
L
M
N
N
L
E
I
T
Y
S
T
E
T
E
K
L
R
S
D
V
E
R
L
R
M
S
E
E
E
A
K
N
A
T
N
R
V
L
S
L
Q
E
E
I
A
K
L
R
K
E
L
H
Q
T
Q
T
E
K
K
T
I
E
E
W
A
D
K
Y
K
H
E
T
E
Q
L
V
S
E
L
K
E
Q
N
T
L
L
K
T
E
K
-----
E
E
L
N
R
R
I
H
D
Q
A
K
E
I
T
E
T
M
E
K
K
L
V
E
E
T
K
Q
L
E
L
D
L
N
D
E
R
L
R
Y
Q
----
34
HHSearch
56.01
21%
40
- C3 -
-
2ENP
-
A:
[24-129]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
H
N
H
----
L
T
V
R
V
I
E
A
R
D
L
P
P
P
I
S
HDGSRQD
M
A
H
S
N
P
Y
V
------
K
I
C
L
L
P
D
Q
K
N
S
----
K
Q
T
G
-
V
--
K
R
K
T
Q
K
P
V
F
E
E
R
Y
------
T
F
-
E
-
I
P
-
F
L
E
A
Q
-
R
R
T
L
L
L
T
V
V
D
F
D
KFS
R
-----
H
C
V
I
G
--
K
V
S
V
P
-
L
C
E
V
--
D
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
HHSearch
53.72
22%
-56
* C3 *
-
4TS6
1
?
A:
[22-122]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
L
Q
----
L
I
V
T
L
V
C
A
T
G
L
S
L
R
Q
S
-------
G
A
G
R
N
P
Y
A
------
K
V
F
L
L
P
D
R
S
H
K
S
--
K
R
R
T
-
K
T
--
V
G
T
T
C
E
P
R
W
G
Q
T
F
------
V
Y
-
S
-
G
L
R
R
C
D
L
N
-
G
R
L
L
E
V
T
L
W
D
Y
V
RYG
A
-----
N
D
F
I
G
--
E
V
V
I
D
-
L
A
H
H
--
I
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
53.34
21%
17
- C3 -
-
4NP9
1
A:
[18-127]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
N
S
N
----
L
Q
C
T
I
I
R
A
K
G
L
K
P
M
D
S
-------
N
G
L
A
D
P
Y
V
------
K
L
H
L
L
P
G
A
S
K
S
N
--
K
L
R
T
K
-
T
--
L
R
N
T
R
N
P
V
W
N
E
T
L
------
Q
Y
-
H
G
I
T
-
E
E
D
M
Q
-
R
K
T
L
R
I
S
V
C
D
E
D
KFG
H
-----
N
E
F
I
G
--
E
T
R
F
S
-
L
K
K
L
--
K
A
N
Q
---
R
K
N
F
N
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
HHSearch
52.72
21%
24
- C3 -
-
4NS0
1
A:
[18-127]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
N
S
N
----
L
Q
C
T
I
I
R
A
K
G
L
K
P
M
D
S
-------
N
G
L
A
D
P
Y
V
------
K
L
H
L
L
P
G
A
S
K
S
N
--
K
L
R
T
K
-
T
--
L
R
N
T
R
N
P
V
W
N
E
T
L
------
Q
Y
-
H
G
I
T
-
E
E
D
M
Q
-
R
K
T
L
R
I
S
V
C
D
E
D
KFG
H
-----
N
E
F
I
G
--
E
T
R
F
S
-
L
K
K
L
--
K
A
N
Q
---
R
K
N
F
N
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
51.57
16%
-77
- C3 -
-
2EP6
-
A:
[90-197]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
G
D
V
K
D
V
G
I
----
L
Q
V
K
V
L
K
A
A
D
L
L
A
A
D
F
-------
S
G
K
S
D
P
F
C
------
L
L
E
L
G
N
D
R
-------
L
Q
T
H
T
---
V
Y
K
N
L
N
P
E
W
N
K
V
F
------
T
F
-
P
-
I
K
-
D
I
H
----
D
V
L
E
V
T
V
F
D
E
D
GD
K
P
-----
P
D
F
L
G
--
K
V
A
I
P
-
L
L
S
I
--
R
D
G
Q
---
P
N
C
Y
V
L
K
N
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
HHSearch
51.02
15%
-52
- C3 -
-
2DMG
-
A:
[22-136]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
R
N
K
----
L
I
V
V
V
H
A
C
R
N
L
I
A
F
S
E
-------
D
G
-
S
D
P
Y
V
------
R
M
Y
L
L
P
D
K
R
R
S
G
--
R
R
K
T
H
-
V
--
S
K
K
T
L
N
P
V
F
D
Q
S
F
------
D
F
-
S
-
V
S
-
L
P
E
V
Q
-
R
R
T
L
D
V
A
V
K
N
S
G
---
G
FLSKD
K
G
L
L
G
--
K
V
L
V
A
-
L
A
S
E
EL
A
K
G
W
---
T
Q
W
Y
D
L
T
E
D
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
HHSearch
49.33
22%
-78
- C3 -
-
5W5C
-
F:
[15-112]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
N
N
Q
----
L
L
V
G
I
I
Q
A
A
E
L
P
-------------
T
S
D
P
Y
V
------
K
V
F
L
L
P
---
K
----
K
F
E
T
K
V
---
H
R
K
T
L
N
P
V
F
N
E
Q
F
------
T
F
-
K
-
V
P
-
Y
S
E
L
G
-
G
K
T
L
V
M
A
V
Y
D
F
D
-----------
I
I
G
--
E
F
K
V
P
-
M
N
T
V
--
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
48.31
18%
-45
- C3 -
-
4LDC
-
A:
[17-127]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
Q
G
----
L
L
V
G
I
V
R
C
A
H
L
A
A
M
D
A
-------
N
G
Y
S
D
P
Y
V
------
K
T
Y
L
K
P
D
V
D
K
K
S
--
K
H
K
T
A
-
V
--
K
K
K
T
L
N
P
E
F
N
E
E
F
------
C
Y
-
E
-
I
K
-
H
G
D
L
A
-
K
K
T
L
E
V
T
V
W
D
Y
D
I
GK
S
-----
N
D
F
I
G
--
G
V
V
L
G
-
I
N
A
K
--
G
E
R
L
---
K
H
W
F
D
C
L
K
N
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
HHSearch
48.27
18%
-46
- C3 -
-
1UOW
1
A:
[24-134]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
G
K
----
L
T
V
V
I
L
E
A
K
N
L
K
K
M
D
V
-------
G
G
L
S
D
P
Y
V
------
K
I
H
L
M
Q
N
G
K
R
L
--
K
K
K
K
T
T
I
---
K
K
N
T
L
N
P
Y
Y
N
E
S
F
------
S
F
-
E
-
V
P
-
F
E
Q
I
Q
-
K
V
Q
V
V
V
T
V
L
D
Y
D
KIG
K
-----
N
D
A
I
G
--
K
V
F
V
G
-
Y
N
S
T
--
G
A
E
L
---
R
H
W
S
D
M
L
A
N
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
47.90
27%
-60
- C2 -
-
4R61
-
?
A:
[10-140]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
Q
K
Q
N
N
L
L
R
Q
I
E
-
A
Q
Q
H
-
L
L
Q
L
T
V
S
K
I
K
Q
L
Q
A
R
I
L
A
V
E
R
Y
L
K
D
Q
Q
-----
Q
P
----
Q
----
Q
D
K
L
Y
R
E
V
A
L
I
R
A
Q
L
Q
K
I
E
S
--
E
T
L
Q
------
L
L
H
Q
Q
A
E
I
E
R
E
L
--
N
N
Q
E
Q
E
I
G
S
L
K
Q
R
-------
G
I
D
Q
R
Q
N
N
L
K
R
A
I
E
A
Q
K
H
L
L
Q
L
-----------------------------------------------------------------------------------
31
HHSearch
47.01
19%
-10
- C3 -
-
2DMH
-
MYOF_HUMAN
A:
[5-101]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
S
G
M
----
L
R
V
I
V
E
S
A
S
N
I
P
K
T
K
--------
F
G
K
P
D
P
I
V
------
S
V
I
F
K
D
E
-------
K
K
K
T
-
K
K
--
V
D
N
E
L
N
P
V
W
N
E
I
L
------
E
F
-
D
-
L
R
-
G
I
P
L
D
F
S
S
S
L
G
I
I
V
K
D
F
E
---
T
IGQ--
N
K
L
I
G
--
T
A
T
V
A
-
L
K
D
L
--
T
G
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
HHSearch
45.75
16%
-14
- C3 -
-
1UGK
-
A:
[21-133]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
K
A
----
F
V
V
N
I
K
E
A
R
G
L
P
A
M
D
E
Q------
S
M
T
S
D
P
Y
I
------
K
M
T
I
L
P
E
K
K
H
K
----
V
K
T
-
R
V
--
L
R
K
T
L
D
P
A
F
D
E
T
F
------
T
F
Y
G
-
I
P
-
Y
T
Q
I
Q
-
E
L
A
L
H
F
T
I
L
S
F
D
R
FS
R
-----
D
D
I
I
G
--
E
V
L
I
P
-
L
S
G
I
--
E
L
S
E
G
K
M
L
M
N
R
E
I
I
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38
Fugue
44.24
13%
-46
- C2 -
-
4ZRY
-
B:
[17-120]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
H
G
D
S
V
R
N
S
K
I
E
I
S
E
L
------
N
R
V
I
Q
R
L
R
S
E
I
D
N
V
K
K
Q
I
S
N
L
--
Q
Q
S
I
S
D
A
E
Q
R
G
E
N
A
L
K
D
A
K
N
K
L
N
D
L
E
D
A
L
Q
Q
A
K
E
D
--
L
A
R
L
L
R
D
Y
Q
E
L
M
N
T
K
L
A
L
D
L
E
I
A
T
Y
R
T
L
L
E
G
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
43.27
18%
53
- C2 -
-
2XKJ
-
?
E:
[543-712]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
A
K
K
L
P
L
V
V
D
V
R
D
E
S
D
H
E
N
P
T
R
L
V
I
V
L
RSNRID
A
E
A
V
M
S
H
L
F
A
T
T
D
L
E
S
S
Y
R
V
N
--
L
N
M
I
G
E
D
G
R
P
Q
V
K
S
I
R
R
I
L
L
E
W
I
E
I
R
K
K
T
V
T
R
R
L
Q
YH
L
N
R
I
E
K
R
L
H
I
L
A
G
L
L
I
A
Y
L
D
I
D
T
V
I
R
I
I
R
E
E
D
Q
P
K
P
V
L
M
E
H
F
N
I
D
E
I
Q
-
A
E
A
I
L
E
L
K
L
R
H
L
A
K
L
E
E
M
E
I
R
H
E
Q
D
E
L
S
A
K
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
44
Fugue
42.87
15%
27
- C2 -
-
2A3D
-
?
A:
[1-73]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
G
S
--
W
A
E
F
K
Q
R
L
A
A
I
K
T
R
L
Q
A
L
G
G
S
E
A
E
L
A
A
F
E
K
E
I
A
A
F
E
S
E
L
Q
A
Y
K
-
G
K
G
N
P
E
V
E
A
L
R
K
E
A
A
A
I
R
D
E
L
Q
A
Y
R
H
N
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
HHSearch
41.91
23%
-15
- C3 -
-
2K45
-
A:
[16-113]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
N
Q
----
L
L
V
G
I
I
Q
A
A
E
L
P
A
L
D
M
-------
G
G
T
S
D
P
Y
V
------
K
V
F
L
L
P
D
K
K
K
----
K
F
E
T
K
V
---
H
R
K
T
L
N
P
V
F
N
E
Q
F
------
T
F
-
K
-
V
P
-
Y
S
E
L
G
-
G
K
T
L
V
M
A
V
Y
D
F
D
RFS
K
-----
H
D
I
I
G
--
E
F
K
V
P
-
M
N
T
V
--
D
F
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
HHSearch
40.15
15%
-52
- C3 -
-
5LOW
-
RP3A_RAT
I:
[36-145]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
G
G
----
L
I
V
G
I
I
R
C
V
H
L
A
A
M
D
A
-------
N
G
Y
S
D
P
F
V
------
K
L
W
L
K
P
D
M
G
K
K
--
A
K
H
K
T
Q
-
I
--
K
K
K
T
L
N
P
E
F
N
E
E
F
------
F
Y
-
D
-
I
K
-
H
S
D
L
A
-
K
K
S
L
D
I
S
V
W
D
Y
D
IGK
S
-----
N
D
Y
I
G
--
G
C
Q
L
G
-
I
S
A
K
--
G
E
R
L
---
K
H
W
Y
E
C
L
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
HHSearch
39.88
15%
-60
- C3 -
-
2CM6
-
RP3A_RAT
A:
[36-145]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
G
G
----
L
I
V
G
I
I
R
C
V
H
L
A
A
M
D
A
-------
N
G
Y
S
D
P
F
V
------
K
L
W
L
K
P
---
K
K
A
--
K
H
K
T
Q
-
I
--
K
K
K
T
L
N
P
E
F
N
E
E
F
------
F
Y
-
D
-
I
K
-
H
S
D
L
A
-
K
K
S
L
D
I
S
V
W
D
Y
D
IGK
S
-----
N
D
Y
I
G
--
G
C
Q
L
G
-
I
S
A
K
--
G
E
R
L
---
K
H
W
Y
E
C
L
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------