@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : FBX3_HUMAN: (2018-07-13 )
MAAMETETAPLTLESLPTDPLLLILSFLDYRDLINCCYVSRRLSQLSSHDPLWRRHCKKYWLISEEEKTQKNQCWKSLFIDTYSDVGRYIDHYAAIKKAWDDLKKYLEPRCPRMVLSLKEGAREEDLDAVEAQIGCKLPDDYRCSYRIHNGQKLVVPGLLGSMALSNHYRSEDLLDVDTAAGGFQQRQGLKYCLPLTFCIHTGLSQYIAVEAAEGRNKNEVFYQCPDQMARNPAAIDMFIIGATFTDWFTSYVKNVVSGGFPIIRDQIFRYVHDPECVATTGDITVSVSTSFLPELSSVHPPHYFFTYRIRIEMSKDALPEKACQLDSRYWRITNAKGDVEEVQGPGVVGEFPIISPGRVYEYTSCTTFSTTSGYMEGYYTFHFLYFKDKIFNVAIPRFHMACPTFRVSIARLEMGPDEYEEMEEEEEEEEEEDEDDDSADMDESDEDDEEERRRRVFDVPIRRRRCSRLF
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140...--------....150.......160...--....170.......180...-....---190.......------200.......210.....--------------..220.......230.....-..240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370...-....380........390.......400.......410.......420.......430.......440.......450.......460.......470
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MAAMETETA
P
L
T
L
ESLPT
D
P
L
L
L
I
L
S
F
L
D
Y
R
D
L
I
N
C
C
Y
V
S
R
R
L
S
Q
LSSH
D
P
L
W
R
R
H
C
K
K
Y
W
L
IS
E
E
E
K
T
Q
K
N
Q
C
W
K
S
L
F
I
D
T
Y
S
D
V
G
R
Y
I
D
H
Y
A
A
I
K
K
A
W
D
D
L
K
K
Y
LEPRC
P
R
M
V
L
S
L
KEGAREE
D
L
D
A
V
E
A
Q
IGCKLPDDY
R
C
S
--------
Y
R
IHNG
Q
K
L
V
V
P
G
L
L
G
S
M
A
L
--SNHYRSEDLLDVDTAAG
G
F
Q
-QRQG---L
K
Y
C
L
P
L
T
F
C
------
I
HTGL
S
Q
Y
I
A
V
E
AAEGRN--------------KN
E
V
F
Y
QC
P
D
Q
MARNP
A
A
I
D
-
M
F
I
I
GA
T
F
T
D
W
F
T
S
Y
V
K
N
V
V
SGGF
P
I
I
R
D
Q
I
F
R
Y
VHDPE
C
V
A
TTG
D
I
T
V
S
V
S
T
S
F
L
P
E
L
SSVHPP
H
Y
F
F
T
Y
R
I
R
I
E
MSKDAL
P
E
K
A
C
QLDS
R
Y
W
R
I
TNAKG
D
V
E
E
VQGPGVVGEFPIISPG
R
V
Y
E
Y
T
S
C
T
T
FSTTSGY-
M
E
G
Y
Y
-
T
F
H
F
L
Y
F
KD
K
I
F
NVAIP
R
F
HMACP
T
F
R
V
S
I
A
R
LEMG
P
D
E
Y
E
E
M
E
E
E
E
E
EEEEEDEDDDSADMDESDED
D
E
E
E
R
R
R
RVFDV
P
I
R
R
R
R
C
SRLF
30
HHSearch
93.35
99%
-153
- C3 -
-
5HDW
-
A:
[3-131]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
V
A
T
T
G
D
I
T
V
S
V
S
T
S
F
L
P
E
L
S
S
V
H
P
P
H
Y
F
F
T
Y
R
I
R
I
E
M
S
K
D
A
L
P
E
K
A
C
Q
L
D
S
R
Y
W
R
I
T
N
A
K
G
D
V
E
E
V
Q
G
P
G
V
V
G
E
F
P
I
I
S
P
G
R
V
Y
E
Y
T
S
C
T
T
F
S
T
T
S
G
Y
-
M
E
G
Y
Y
-
T
F
H
F
L
Y
F
K
D
K
I
F
N
V
A
I
P
R
F
H
M
A
C
P
T
------------------------------------------------------------------
1
PsiBlast_PDB
92.69
99%
-149
- C3 -
-
5HDW
-
A:
[2-131]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
F
V
A
T
T
G
D
I
T
V
S
V
S
T
S
F
L
P
E
L
S
S
V
H
P
P
H
Y
F
F
T
Y
R
I
R
I
E
M
S
K
D
A
L
P
E
K
A
C
Q
L
D
S
R
Y
W
R
I
T
N
A
K
G
D
V
E
E
V
Q
G
P
G
V
V
G
E
F
P
I
I
S
P
G
R
V
Y
E
Y
T
S
C
T
T
F
S
T
T
S
G
Y
-
M
E
G
Y
Y
-
T
F
H
F
L
Y
F
K
D
K
I
F
N
V
A
I
P
R
F
H
M
A
C
P
T
------------------------------------------------------------------
32
HHSearch
74.00
40%
-109
- C3 -
-
1TZA
-
APAG_SHEON
B:
[3-125]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
L
D
N
S
I
R
V
E
V
K
T
E
Y
I
E
Q
Q
S
S
---
E
K
Y
L
F
S
Y
T
I
T
I
I
N
L
G
----
E
Q
A
A
K
L
E
T
R
H
W
I
I
T
D
A
N
G
K
T
S
E
V
Q
G
A
G
V
V
G
E
T
P
T
I
P
P
N
T
A
Y
Q
Y
T
S
G
T
V
L
D
T
P
F
G
I
-
M
Y
G
T
Y
-
G
M
V
S
E
--
S
G
E
H
F
N
A
I
I
K
P
F
R
L
A
T
P
G
L
L
----------------------------------------------------------------
33
HHSearch
73.45
36%
-138
* C3 *
-
1XQ4
-
APAG_BORPE
A:
[7-129]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
V
K
P
Y
D
L
T
V
S
V
T
P
R
Y
V
P
E
Q
S
D
P
S
Q
Q
Q
Y
V
F
A
Y
T
V
R
I
T
N
T
G
----
S
H
P
A
Q
V
I
S
R
H
W
I
I
T
D
G
E
E
R
V
Q
E
V
R
G
L
G
V
V
G
Q
Q
P
L
L
A
P
G
E
T
F
E
Y
T
S
G
C
P
L
P
T
P
I
G
T
-
M
R
G
T
Y
-
H
C
V
G
--
E
N
G
I
P
F
E
V
P
I
A
E
F
L
L
A
M
P
R
T
-----------------------------------------------------------------
31
HHSearch
71.93
40%
-114
- C3 -
-
1TZA
-
APAG_SHEON
A:
[3-125]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
L
D
N
S
I
R
V
E
V
K
T
E
Y
I
E
Q
Q
S
S
P
E
D
E
K
Y
L
F
S
Y
T
I
T
I
I
N
L
G
----
E
Q
A
A
K
L
E
T
R
H
W
I
I
T
D
A
N
G
K
T
S
E
V
Q
G
A
G
V
V
G
E
T
P
T
I
P
P
N
T
A
Y
Q
Y
T
S
G
T
V
L
D
T
P
F
G
I
-
M
Y
G
T
Y
-
G
M
V
S
E
--
S
G
E
H
F
N
A
I
I
K
P
F
R
L
A
T
P
G
L
L
----------------------------------------------------------------
2
PsiBlast_PDB
70.95
38%
-119
- C3 -
-
1TZA
-
APAG_SHEON
A:
[3-122]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
L
D
N
S
I
R
V
E
V
K
T
E
Y
I
E
Q
Q
S
S
P
E
D
E
K
Y
L
F
S
Y
T
I
T
I
----
I
N
L
G
E
Q
A
A
K
L
E
T
R
H
W
I
I
T
D
A
N
G
K
T
S
E
V
Q
G
A
G
V
V
G
E
T
P
T
I
P
P
N
T
A
Y
Q
Y
T
S
G
T
V
L
D
T
P
F
G
I
-
M
--
Y
G
-
T
Y
G
M
V
S
E
S
G
E
H
F
N
A
I
I
K
P
F
R
L
A
T
P
-------------------------------------------------------------------
35
HHSearch
70.18
34%
-113
- C3 -
-
1XVS
1
APAG_VIBCH
A:
[3-124]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
S
L
P
C
I
K
I
Q
V
Q
T
R
Y
I
E
E
Q
S
N
P
E
Y
Q
R
F
V
F
A
Y
L
I
T
I
K
N
L
S
----
S
Q
T
V
Q
L
M
S
R
R
W
L
I
T
D
A
D
G
K
Q
T
V
V
E
G
D
G
V
V
G
E
Q
P
R
I
K
A
N
D
E
Y
T
Y
S
S
G
T
A
L
D
T
P
V
G
V
-
M
Q
G
Q
Y
-
L
M
I
D
--
E
Q
G
E
S
F
T
V
E
I
E
P
F
R
L
A
V
P
H
V
-----------------------------------------------------------------
3
PsiBlast_PDB
70.00
36%
-152
- C3 -
-
1XQ4
-
APAG_BORPE
A:
[12-127]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
L
T
V
S
V
T
P
R
Y
V
P
E
Q
S
D
P
S
Q
Q
Q
Y
V
F
A
Y
T
V
R
I
T
N
T
G
S
----
H
P
A
Q
V
I
S
R
H
W
I
I
T
D
G
E
E
R
V
Q
E
V
R
G
L
G
V
V
G
Q
Q
P
L
L
A
P
G
E
T
F
E
Y
T
S
G
C
P
L
P
T
P
I
G
T
-
M
R
G
---
T
Y
H
C
V
G
E
N
G
I
P
F
E
V
P
I
A
E
F
L
L
A
M
P
-------------------------------------------------------------------
5
PsiBlast_PDB
69.91
34%
-125
- C3 -
-
1XVS
1
APAG_VIBCH
A:
[8-122]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
K
I
Q
V
Q
T
R
Y
I
E
E
Q
S
N
P
E
Y
Q
R
F
V
F
A
Y
L
I
T
I
K
----
N
L
S
S
Q
T
V
Q
L
M
S
R
R
W
L
I
T
D
A
D
G
K
Q
T
V
V
E
G
D
G
V
V
G
E
Q
P
R
I
K
A
N
D
E
Y
T
Y
S
S
G
T
A
L
D
T
P
V
G
V
-
M
Q
G
Q
Y
-
L
--
M
I
D
E
Q
G
E
S
F
T
V
E
I
E
P
F
R
L
A
V
P
-------------------------------------------------------------------
34
HHSearch
65.69
33%
-115
- C3 -
-
2F1E
-
APAG_XANAC
A:
[6-121]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
Y
R
V
E
V
E
V
S
P
R
F
L
A
H
Q
S
T
P
D
E
G
R
Y
A
F
A
Y
S
I
R
I
Q
N
A
G
----
A
V
P
A
R
L
V
A
R
H
W
Q
I
T
D
G
N
G
R
T
E
Q
V
D
G
E
G
V
V
G
E
Q
P
W
L
R
P
G
E
A
F
H
Y
T
S
G
V
L
L
E
T
E
Q
G
Q
-
M
Q
G
H
Y
-
D
M
V
A
D
--
D
G
T
E
F
I
A
P
I
A
A
F
V
L
S
---------------------------------------------------------------------
21
Fugue
65.13
36%
-77
- C3 -
-
1TZA
-
APAG_SHEON
A:
[3-134]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
L
D
N
S
I
R
V
E
V
K
T
E
Y
I
E
Q
Q
S
S
P
E
D
E
K
Y
L
F
S
Y
T
I
T
I
I
N
L
----
G
E
Q
A
A
K
L
E
T
R
H
W
I
I
T
D
A
N
G
K
T
S
E
V
Q
G
A
G
V
V
G
E
T
P
T
I
P
P
N
T
A
Y
Q
Y
T
S
G
T
V
L
D
T
P
F
G
I
M
Y
G
T
Y
G
M
V
S
E
----
S
G
E
H
F
N
A
I
I
K
P
F
R
L
A
T
P
G
L
L
H
L
E
H
H
H
H
H
H
-------------------------------------------------------
4
PsiBlast_PDB
60.42
40%
-84
- C3 -
-
2F1E
-
APAG_XANAC
A:
[9-101]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
E
V
E
V
S
P
R
F
L
A
H
Q
S
T
P
D
E
G
R
Y
A
F
A
Y
S
I
R
I
Q
-
N
A
G
A
V
P
A
R
---
L
V
A
R
H
W
Q
I
T
D
G
N
G
R
T
E
Q
V
D
G
E
G
V
V
G
E
Q
P
W
L
R
P
G
E
A
F
H
Y
T
S
G
V
L
L
E
T
E
Q
G
Q
-
M
Q
G
H
Y
--------------------------------------------------------------------------------------------
7
PsiBlast_PDB
48.69
26%
48
- C1 -
-
2X58
-
ECHP_RAT
A:
[500-686]
---------------------------------------------------------------------------------------------------------------------
L
E
E
G
S
K
P
E
D
V
D
G
V
L
E
E
F
G
F
K
M
-
G
P
F
R
V
S
D
L
A
G
L
D
V
G
W
K
I
R
K
G
Q
G
L
T
G
P
S
L
P
P
G
T
P
V
RK
R
G
N
S
R
Y
S
P
L
G
D
M
L
C
E
A
G
R
F
G
-
Q
K
T
G
KGW
Y
Q
Y
D
K
P
L
G
R
I
H
K
P
D
P
W
L
S
T
F
L
S
Q
Y
R
E
V
H
H
I
E
Q
R
T
IS
K
E
E
I
L
E
R
C
L
Y
S
L
I
N
E
A
F
R
I
L
E
E
G
M
A
A
R
P
E
H
I
D
V
I
Y
L
H
G
Y
G
W
P
R
H
K
G
G
P
M
F
Y
A
A
S
V
G
L
P
T
V
L
E
K
L
Q
K
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
48.42
26%
46
- C1 -
-
5OMO
2
ECHP_RAT
A:
[515-701]
---------------------------------------------------------------------------------------------------------------------
L
E
E
G
S
K
P
E
D
V
D
G
V
L
E
E
F
G
F
K
M
-
G
P
F
R
V
S
D
L
A
G
L
D
V
G
W
K
I
R
K
G
Q
G
L
T
G
P
S
L
P
P
G
T
P
V
RK
R
G
N
S
R
Y
S
P
L
G
D
M
L
C
E
A
G
R
F
G
-
Q
K
T
G
KGW
Y
Q
Y
D
K
P
L
G
R
I
H
K
P
D
P
W
L
S
T
F
L
S
Q
Y
R
E
V
H
H
I
E
Q
R
T
IS
K
E
E
I
L
E
R
C
L
Y
S
L
I
N
E
A
F
R
I
L
E
E
G
M
A
A
R
P
E
H
I
D
V
I
Y
L
H
G
Y
G
W
P
R
H
K
G
G
P
M
F
Y
A
A
S
V
G
L
P
T
V
L
E
K
L
Q
K
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
39
HHSearch
47.77
12%
-58
- C2 -
-
2PRV
10
YOBK_BACSU
A:
[4-143]
---------------------------------------------------------------------------------------------------
Y
S
K
V
E
N
F
I
N
E
N
K
Q
N
--
A
I
F
T
E
G
A
S
H
E
N
I
G
R
I
E
E
N
L
Q
C
D
L
P
N
S
Y
K
W
F
--------
L
E
K
Y
G
A
G
G
L
F
G
V
L
V
L
G
Y
N
-
F
---
D
H
---
A
S
V
V
N
R
---
T
N
E
Y
K
E
H
Y
G
L
---
T
D
G
L
V
V
I
E
D
V
--------
D
Y
F
A
Y
C
L
D
T
N
K
M
K
D
-
G
--------------
E
C
P
V
V
E
W
D
R
V
I
G
Y
--------
Q
D
T
V
A
D
S
F
I
E
F
F
Y
N
K
I
Q
E
A
K
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
47.64
26%
42
- C1 -
-
5MGB
3
ECHP_RAT
A:
[515-701]
---------------------------------------------------------------------------------------------------------------------
L
E
E
G
S
K
P
E
D
V
D
G
V
L
E
E
F
G
F
K
M
-
G
P
F
R
V
S
D
L
A
G
L
D
V
G
W
K
I
R
K
G
Q
G
L
T
G
P
S
L
P
P
G
T
P
V
RK
R
G
N
S
R
Y
S
P
L
G
D
M
L
C
E
A
G
R
F
G
-
Q
K
T
G
KGW
Y
Q
Y
D
K
P
L
G
R
I
H
K
P
D
P
W
L
S
T
F
L
S
Q
Y
R
E
V
H
H
I
E
Q
R
T
IS
K
E
E
I
L
E
R
C
L
Y
S
L
I
N
E
A
F
R
I
L
E
E
G
M
A
A
R
P
E
H
I
D
V
I
Y
L
H
G
Y
G
W
P
R
H
K
G
G
P
M
F
Y
A
A
S
V
G
L
P
T
V
L
E
K
L
Q
K
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
47.63
26%
50
- C1 -
-
3ZW8
-
ECHP_RAT
A:
[515-701]
---------------------------------------------------------------------------------------------------------------------
L
E
E
G
S
K
P
E
D
V
D
G
V
L
E
E
F
G
F
K
M
-
G
P
F
R
V
S
D
L
A
G
L
D
V
G
W
K
I
R
K
G
Q
G
L
T
G
P
S
L
P
P
G
T
P
V
RK
R
G
N
S
R
Y
S
P
L
G
D
M
L
C
E
A
G
R
F
G
-
Q
K
T
G
KGW
Y
Q
Y
D
K
P
L
G
R
I
H
K
P
D
P
W
L
S
T
F
L
S
Q
Y
R
E
V
H
H
I
E
Q
R
T
IS
K
E
E
I
L
E
R
C
L
Y
S
L
I
N
E
A
F
R
I
L
E
E
G
M
A
A
R
P
E
H
I
D
V
I
Y
L
H
G
Y
G
W
P
R
H
K
G
G
P
M
F
Y
A
A
S
V
G
L
P
T
V
L
E
K
L
Q
K
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
47.51
26%
47
- C1 -
-
3ZWA
-
ECHP_RAT
A:
[515-701]
---------------------------------------------------------------------------------------------------------------------
L
E
E
G
S
K
P
E
D
V
D
G
V
L
E
E
F
G
F
K
M
-
G
P
F
R
V
S
D
L
A
GL
D
V
G
W
K
I
R
K
G
Q
G
L
T
G
P
S
L
P
P
G
T
P
V
RK
R
G
N
S
R
Y
S
P
L
G
D
M
L
C
E
A
G
R
F
G
-
Q
K
T
G
KGW
Y
Q
Y
D
K
P
L
G
R
I
HKPD
P
W
L
S
T
F
L
S
Q
Y
R
E
V
H
H
I
E
Q
R
T
I
S
K
E
E
I
L
E
R
C
L
Y
S
L
I
N
E
A
F
R
I
L
E
E
G
M
A
A
R
P
E
H
I
D
V
I
Y
L
H
G
Y
G
W
P
R
H
K
G
G
P
M
F
Y
A
A
S
V
G
L
P
T
V
L
E
K
L
Q
K
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
41
HHSearch
47.49
15%
-72
- C2 -
-
3D5P
-
?
A:
[9-133]
-------------------------------------------------------------------------------------------------------------------
W
Y
K
K
D
G
A
S
S
A
S
I
D
D
V
E
K
L
L
N
T
T
L
P
K
Q
Y
K
S
F
--------
L
L
W
S
N
G
G
E
G
K
L
G
--
D
N
Y
I
Y
I
--
W
A
I
---
E
D
V
I
A
Y
N
H
---
D
Y
G
I
Q
K
Y
L
---
Q
K
E
Y
W
A
F
G
M
D
------
G
-
D
I
G
Y
I
L
H
L
S
D
---------------------
N
S
I
Y
R
V
D
L
G
D
L
D
----
I
T
S
-
I
K
Y
I
A
P
S
F
D
D
F
L
G
K
A
I
Y
L
N
F
N
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
47.49
25%
27
- C- -
-
1ZCJ
-
ECHP_RAT
A:
[482-681]
--------------------------------------------------------------------------------------------------------
R
M
L
A
P
Y
Y
N
Q
G
F
F
L
L
E
E
G
S
K
P
E
D
V
D
G
V
L
E
E
F
G
F
K
M
-
G
P
F
R
V
S
D
L
A
G
L
D
V
G
W
K
I
R
K
G
Q
G
L
T
G
P
S
L
P
P
G
T
P
V
RK
R
G
N
S
R
Y
S
P
L
G
D
M
L
C
E
A
G
R
F
G
-
Q
K
T
G
KGW
Y
Q
Y
D
K
P
L
G
R
I
HKPD
P
W
L
S
T
F
L
S
Q
Y
R
E
V
H
H
I
E
Q
R
T
IS
K
E
E
I
L
E
R
C
L
Y
S
L
I
N
E
A
F
R
I
L
E
E
G
M
A
A
R
P
E
H
I
D
V
I
Y
L
H
G
Y
G
W
P
R
H
K
G
G
P
M
F
Y
A
A
S
V
G
L
P
T
V
L
E
K
L
Q
K
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------