@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : NGAP_HUMAN: (2018-07-13 )
MQTPEVPAERSPRRRSISGTSTSEKPNSMDTANTSPFKVPGFFSKRLKGSIKRTKSQSKLDRNTSFRLPSLRSTDDRSRGLPKLKESRSHESLLSPCSTVECLDLGRGEPVSVKPLHSSILGQDFCFEVTYLSGSKCFSCNSASERDKWMENLRRTVQPNKDNCRRAENVLRLWIIEAKDLAPKKKYFCELCLDDTLFARTTSKTKADNIFWGEHFEFFSLPPLHSITVHIYKDVEKKKKKDKNNYVGLVNIPTASVTGRQFVEKWYPVSTPTPNKGKTGGPSIRIKSRFQTITILPMEQYKEFAEFVTSNYTMLCSVLEPVISVRNKEELACALVHILQSTGRAKDFLTDLVMSEVDRCGEHDVLIFRENTIATKSIEEYLKLVGQQYLHDALGEFIKALYESDENCEVDPSKCSSSELIDHQSNLKMCCELAFCKIINSYCVFPRELKEVFASWKQQCLNRGKQDISERLISASLFLRFLCPAIMSPSLFNLMQEYPDDRTSRTLTLIAKVIQNLANFAKFGNKEEYMAFMNDFLEHEWGGMKRFLLEISNPDTISNTPGFDGYIDLGRELSVLHSLLWEVVSQLDKGENSFLQATVAKLGPLPRVLADITKSLTNPTPIQQQLRRFTEHNSSPNVSGSLSSGLQKIFEDPTDSDLHKLKSPSQDNTDSYFRGKTLLLVQQASSQSMTYSEKDERESSLPNGRSVSLMDLQDTHAAQVEHASVMLDVPIRLTGSQLSITQVASIKQLRETQSTPQSAPQVRRPLHPALNQPGGLQPLSFQNPVYHLNNPIPAMPKASIDSSLENLSTASSRSQSNSEDFKLSGPSNSSMEDFTKRSTQSEDFSRRHTVPDRHIPLALPRQNSTGQAQIRKVDQGGLGARAKAPPSLPHSASLRSTGSMSVVSAALVAEPVQNGSRSRQQSSSSRESPVPKVRAIQRQQTQQVQSPVDSATMSPVERTAAWVLNNGQYEEDVEETEQNLDEAKHAEKYEQEITKLKERLRVSSRRLEEYERRLLVQEQQMQKLLLEYKARLEDSEERLRRQQEEKDSQMKSIISRLMAVEEELKKDHAEMQAVIDAKQKIIDAQEKRIVSLDSANTRLMSALTQVKERYSMQVRNGISPTNPTKLSITENGEFKNSSC
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.--------.---------------.....190....-----...200.......210.......220.----......230.......240.......250.......260--.--.-----------------------------------.--......270..-------.....280.......290.......300.......310.......320........-330.......340-----........350----.......360.......370....-...380.-......390.......400...-.....410.....--------------------------------..420-----------------------------.......----..430.......440....---...450.......460....---.-------..470.......480........490...------..----..----500.......510-.......520-.......530.......540.......550.----......560.......570---------.-----------........580.......--590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690.......700.......710.......720.......730.......740.......750.......760.......770.......780.......790.......800.......810.......820.......830.......840.......850.......860.......870.......880.......890.......900.......910.......920.......930.......940.......950.......960.......970.......980.......990.......1000......1010......1020......1030......1040......1050......1060......1070......1080......1090......1100......1110......1120......1130......
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MQTPEVPAERSPRRRSISGTSTSEKPNSMDTANTSPFKVP
G
F
F
S
K
R
L
K
G
S
I
K
RTK
S
Q
SKLDRNTSFRLPSLRST
D
D
R
SRGL
P
K
L
K
ESR
S
H
E
S
L
LSPCS
T
V
E
C
L
DLGRGEP
V
S
V
K
P
L
H
S
S
ILGQD
F
C
F
E
V
T
YLSGS
K
C
FSCNS
A
S
E
R
D
K
W
M
E
N
L
R
R
TVQPN
K
D
N
C
R
R
A
E
N
V
L
R
L
W
I
I
EAKDLA
P
--------
K
---------------
K
K
Y
F
C
E
LCLDD
T
-----
L
FARTTSKTKADNIFWGE
H
F
E
FFSLPP----L
H
S
I
T
V
H
I
Y
K
D
V
E
K
K
KKKDKNN
Y
V
G
L
V
NIPTASV
T
G
R
----
Q
--
F
-----------------------------------
V
--
E
K
WYPVSTPTP-------NKGKTGG
P
S
I
R
I
K
S
R
F
Q
T
I
T
I
L
P
M
E
Q
Y
K
E
F
A
E
F
V
TS
N
Y
T
M
L
C
S
V
L
E
P
-
V
I
SVR
N
K
E
-
E
L
A
C
A
L
V
H
I
L
Q
S------TG
R
A
K
D
F
L
T
D
L
----
V
M
S
E
V
D
RCGEH
D
V
L
I
F
RENTI
A
T
K
-
S
I
E
E
Y
L
K
-
L
V
G
Q
Q
Y
L
H
D
A
L
G
E
F
I
K
A
L
-YES-DENCEVDPSKCSS--------------------------------
S
E
L
-------------------------------
I
D
H
Q
S
N
L
----
K
M
C
C
E
L
A
F
C
K
I
I
N
S
YCV
F
P
---
R
E
L
K
E
V
F
A
S
W
K
Q
Q
C
L
NR
G
K
Q
---
D
-------
I
S
E
R
L
I
S
A
S
L
F
L
R
F
-
L
C
P
A
IM
S
P
S
L
F
N
L
M
------
Q
E----YP----DDRT
S
R
T
L
T
L
I
A
K
-
V
I
Q
N
L
A
N
F
A
K-FG
N
K
E
E
Y
M
A
F
M
N
D
F
L
E
H
EWG
G
M
K
R
F
L
LEISN----PDTISNTPGFD
G
Y
I
D
L
G
-----------
R
-----------
E
L
S
V
L
H
S
L
L
W
E
V
V
S
Q
L
DK--GE
N
S
F
L
Q
A
T
V
A
KLG
P
L
P
R
V
L
A
D
I
T
K
SLTNP
T
P
I
Q
Q
Q
L
R
R
F
T
EHNSSPNVSG
S
L
S
S
G
L
Q
K
I
FEDPT
D
S
D
L
H
KLKSPSQDNTDSYFRG
K
T
L
L
L
V
QQASSQSMTYS
E
K
D
E
R
ESSLPNG
R
S
V
S
L
M
DLQDT
H
A
A
Q
V
E
H
A
S
V
M
L
D
V
P
I
R
L
TGSQL
S
I
T
Q
V
A
S
I
K
Q
L
R
E
TQSTPQS
A
P
Q
VRRPLHPALNQPGGLQPLSFQNPVYHLNNPIPAMP
K
A
S
I
D
S
S
L
E
N
L
STASSRSQSNSE
D
F
K
LSGPSNS
S
M
E
D
F
T
KRSTQSEDFSRRHTVPDRHI
P
L
ALPRQNST
G
Q
A
Q
I
R
K
VDQGGLGARAKAPPSLPHSASLRSTG
S
M
S
V
V
S
A
A
L
V
A
EPVQNGSRSRQQSSSSRESP
V
P
K
V
R
A
I
Q
R
Q
Q
T
Q
Q
V
QSPVDSATMS
P
V
E
R
T
A
A
W
V
LNNGQ
Y
E
E
D
V
E
E
T
E
Q
N
L
D
E
A
K
H
A
E
K
Y
E
Q
E
I
T
K
L
K
E
R
L
R
V
S
S
R
R
L
E
E
Y
E
R
R
L
L
V
Q
E
Q
Q
M
Q
K
L
L
L
E
Y
K
A
RLE
D
S
E
E
R
L
R
R
Q
Q
E
E
K
D
S
Q
M
K
S
I
I
S
R
L
M
A
V
E
E
E
L
K
K
D
H
A
E
M
Q
A
V
I
D
A
K
Q
K
I
I
D
A
Q
E
K
R
I
V
SLDSA
N
T
R
L
M
S
A
L
T
Q
V
K
E
R
Y
S
M
Q
V
RNGISPTNP
T
K
L
S
ITENGEFKNSSC
15
HHSearch
89.00
67%
-137
- C1 -
-
3BXJ
-
SYGP1_RAT
B:
[237-718]
--------------------------------------------------------------------------------------------------------------------------------------------------------------
P
N
K
D
N
S
R
R
V
D
N
V
L
---------------------------------------------------------------------
G
E
H
F
E
F
N
N
------------------------------------------------
H
--
F
-----------------------------------
T
--
E
Q
--------------------------
R
L
K
A
R
Y
Q
T
M
S
I
L
P
M
E
L
Y
K
E
F
A
E
Y
V
T
N
H
Y
R
M
L
C
A
V
L
E
P
-
A
L
N
V
K
G
K
E
-
E
V
A
S
A
L
V
H
I
L
Q
S
------
T
G
K
A
K
D
F
L
S
D
M
----
A
M
S
E
V
D
R
F
M
E
R
E
H
L
I
F
R
E
N
T
L
A
T
K
-
A
I
E
E
Y
M
R
-
L
I
G
Q
K
Y
L
K
D
A
I
G
E
F
I
R
A
L
-
Y
E
S
-
E
E
N
C
E
V
D
P
I
K
C
T
A
--------------------------------
S
S
L
-------------------------------
A
E
H
Q
A
N
L
----
R
M
C
C
E
L
A
L
C
K
V
V
N
S
H
C
V
F
P
---
R
E
L
K
E
V
F
A
S
W
R
L
R
C
A
E
R
G
R
E
---
D
-------
I
A
D
R
L
I
S
A
S
L
F
L
R
F
-
L
C
P
A
I
M
S
P
S
L
F
G
L
M
------
Q
E
----
Y
P
----
D
E
Q
T
S
R
T
L
T
L
I
A
K
-
V
I
Q
N
L
A
N
F
S
K
-
F
T
S
K
E
D
F
L
G
F
M
N
E
F
L
E
L
E
W
G
S
M
Q
Q
F
L
Y
E
I
S
N
----
L
D
T
L
T
N
S
S
--
E
G
Y
I
D
L
G
-----------
R
-----------
E
L
S
T
L
H
A
L
L
W
E
V
L
P
Q
L
S
K
---------
E
A
L
L
K
L
G
P
L
P
R
L
L
S
D
I
S
T
A
L
R
N
P
N
I
Q
R
Q
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
87.43
63%
-150
- C1 -
-
3BXJ
-
SYGP1_RAT
A:
[238-713]
---------------------------------------------------------------------------------------------------------------------------------------------------------------
N
K
D
N
S
R
R
V
D
N
V
L
----------------------------------------------------------------------
E
H
F
E
F
N
----------------------------------------------------
F
-----------------------------------
T
--
E
Q
W
Y
-------------------------
L
K
A
R
Y
Q
T
M
S
I
L
P
M
E
L
Y
K
E
F
A
E
Y
V
T
N
H
Y
R
M
L
C
A
V
L
E
P
-
A
L
N
V
K
G
K
E
-
E
V
A
S
A
L
V
H
I
L
Q
S
------
T
G
K
A
K
D
F
L
S
D
M
----
A
M
S
E
V
D
R
F
M
E
R
E
H
L
I
F
R
E
N
T
L
A
T
K
-
A
I
E
E
Y
M
R
-
L
I
G
Q
K
Y
L
K
D
A
I
G
E
F
I
R
A
L
-
Y
E
S
-
E
E
N
C
E
V
D
P
I
K
C
T
A
--------------------------------
S
S
L
-------------------------------
A
E
H
Q
A
N
L
----
R
M
C
C
E
L
A
L
C
K
V
V
N
S
H
C
V
F
P
---
R
E
L
K
E
V
F
A
S
W
R
L
R
C
A
E
R
G
R
E
---
D
-------
I
A
D
R
L
I
S
A
S
L
F
L
R
F
-
L
C
P
A
I
M
S
P
S
L
F
G
L
M
------
Q
E
----
Y
P
----
D
E
Q
T
S
R
T
L
T
L
I
A
K
-
V
I
Q
N
L
A
N
F
S
K
-
F
T
S
K
E
D
F
L
G
F
M
N
E
F
L
E
L
E
W
G
S
M
Q
Q
F
L
Y
E
I
S
N
----
L
D
T
L
T
N
S
S
---
G
Y
I
D
L
G
-----------
R
-----------
E
L
S
T
L
H
A
L
L
W
E
V
L
P
Q
L
S
K
---------
E
A
L
L
K
L
G
P
L
P
R
L
L
S
D
I
S
T
A
L
R
N
P
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
HHSearch
67.46
29%
-90
- C1 -
-
1WER
-
RASA1_HUMAN
A:
[718-1033]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
P
E
E
E
Y
S
E
F
K
E
L
I
L
Q
K
E
L
H
V
V
Y
A
L
S
H
-
V
C
G
Q
-
D
R
T
-
L
L
A
S
I
L
L
R
I
F
L
H
------
E
K
L
E
S
L
L
L
C
T
L
----
N
D
R
E
I
S
M
E
D
-
E
A
T
T
L
F
R
A
T
T
L
A
S
T
-
L
M
E
Q
Y
M
K
-
A
T
A
T
Q
F
V
H
H
A
L
K
D
S
I
L
K
I
-
M
E
S
-
K
Q
S
C
E
L
S
P
S
K
L
E
K
N-------------------------------
E
D
V
-------------------------------
N
T
N
L
T
H
L
----
L
N
I
L
S
E
L
V
E
K
I
F
M
A
S
E
I
L
P
---
P
T
L
R
Y
I
Y
G
C
L
Q
K
S
V
Q
H
K
W
P
T
---
N
TT-----
M
R
T
R
V
V
S
G
F
V
F
L
R
L
-
I
C
P
A
I
L
N
P
R
M
F
N
I
I
------
S
D
----
S
P
----
S
P
I
A
A
R
T
L
I
L
V
A
K
-
S
V
Q
N
L
A
N
L
V
E
-
F
G
A
K
E
P
Y
M
E
G
V
N
P
F
I
K
S
N
K
H
R
M
I
M
F
L
D
E
L
G
N
----
V
P
E
L
P
D
T
T
E
-
H
S
R
T
D
L
S
-----------
R
-----------
D
L
A
A
L
H
E
I
C
V
A
H
S
D
E
L
R
T
L
S
N
E
R
G
A
Q
Q
H
V
L
K
K
L
L
A
I
T
E
L
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
63.46
32%
-89
- C1 -
-
1WER
-
RASA1_HUMAN
A:
[718-1001]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
P
E
E
E
Y
S
E
F
K
E
L
I
L
Q
K
E
L
H
V
V
Y
A
L
S
H
-
V
C
G
-
Q
D
R
T
-
L
L
A
S
I
L
L
R
I
F
L
H
------
E
K
L
E
S
L
L
L
C
T
L
----
N
D
R
E
I
S
M
E
D
E
A
T
T
L
-
F
R
A
T
T
L
A
S
T
-
L
M
E
Q
Y
M
K
-
A
T
A
T
Q
F
V
H
H
A
L
K
D
S
I
L
K
I
-
M
E
S
-
K
Q
S
C
E
L
S
P
S
K
L
E
K
--------------------------------
N
E
---------------------------------
D
V
N
T
N
L
T
H
L
L
N
I
L
S
E
L
V
E
-
K
I
F
M
A
S
E
I
L
P
---
P
T
L
R
Y
I
Y
G
-----
C
L
Q
K
S
V
Q
---
H
K
WPTNTT
M
R
T
R
V
V
S
G
F
V
F
L
R
L
-
I
C
P
A
I
L
N
P
R
M
F
N
I
I
------
S
D
----
S
P
----
S
P
I
A
A
R
T
L
I
L
V
A
K
-
S
V
Q
N
L
A
N
L
V
E
-
F
G
A
K
E
P
Y
M
E
G
V
N
P
F
I
K
S
N
K
H
R
M
I
M
F
L
D
E
L
G
N
VPEL
P
D
T
T
E
H
S
R
T
-----
D
L
S
-----------
R
-----------
D
L
A
A
L
H
E
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
63.16
32%
-92
- C1 -
-
1WQ1
2
G:
[5-288]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
P
E
E
E
Y
S
E
F
K
E
L
I
L
Q
K
E
L
H
V
V
Y
A
L
S
H
-
V
C
G
-
Q
D
R
T
-
L
L
A
S
I
L
L
R
I
F
L
H
------
E
K
L
E
S
L
L
L
C
T
L
----
N
D
R
E
I
S
M
E
D
E
A
T
T
L
-
F
R
A
T
T
L
A
S
T
-
L
M
E
Q
Y
M
K
-
A
T
A
T
Q
F
V
H
H
A
L
K
D
S
I
L
K
I
-
M
E
S
-
K
Q
S
C
E
L
S
P
S
K
L
E
K
--------------------------------
N
E
---------------------------------
D
V
N
T
N
L
THLL
N
I
L
S
E
L
V
E
-
K
I
F
M
A
S
E
I
L
P
---
P
T
L
R
Y
I
Y
G
-----
C
L
Q
K
S
V
Q
---
H
KWPTNTT
M
R
T
R
V
V
S
G
F
V
F
L
R
L
-
I
C
P
A
I
L
N
P
R
M
F
N
I
I
------
S
D
----
S
P
----
S
P
I
A
A
R
T
L
I
L
V
A
K
-
S
V
Q
N
L
A
N
L
V
E
-
F
G
A
K
E
P
Y
M
E
G
V
N
P
F
I
K
S
N
K
H
R
M
I
M
F
L
D
E
L
G
N
VPEL
P
D
T
T
E
H
S
R
T
-----
D
L
S
-----------
R
-----------
D
L
A
A
L
H
E
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
HHSearch
49.95
18%
-11
- C1 -
-
3FAY
1
A:
[11-381]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
E
A
Y
Q
H
L
F
Y
L
L
Q
T
N
P
T
Y
L
A
K
L
I
F
Q
-
M
P
Q
N
K
S
T
K
-
F
M
D
S
V
I
F
T
L
Y
N
Y
ASN
Q
R
E
E
Y
L
L
L
R
L
F
K
T
A
----
L
Q
E
E
I
K
S
K
V
D
Q
I
Q
E
I
V
T
G
N
P
T
V
I
K
-
M
V
V
S
F
N
R
G
A
R
G
Q
N
A
L
R
Q
I
L
A
P
V
V
K
E
I
-
M
D
D
K
S
L
N
I
K
T
D
P
V
D
I
Y
K
S
W
V
N
Q
M
E
S
Q
T
GEASKLPYDVT
P
E
Q
A
L
AH
E
E
V
K
T
R
L
-------------------------------
D
S
S
I
R
N
M
----
R
A
V
T
D
K
F
L
S
A
I
V
S
S
V
D
K
I
P
---
Y
G
M
R
F
I
A
K
V
L
K
D
S
L
H
E
K
F
P
D
AG
E
D
-------
E
L
L
K
I
I
G
N
L
L
Y
Y
R
Y
-
M
N
P
A
I
V
A
P
D
A
F
D
I
I
------
D
L
SAG
G
Q
L
----
T
T
D
Q
R
R
N
L
G
S
I
A
K
-
M
L
Q
H
A
A
S
N
K
M
-
F
L
G
D
N
A
H
L
S
I
I
N
E
Y
L
S
Q
S
Y
Q
K
F
R
R
F
F
Q
T
A
C
D
----
V
P
E
L
Q
D
K
F
N
V
D
E
Y
S
D
L
V
TLT
K
P
V
I
Y
I
S
I
G
-----------
E
I
I
N
T
H
T
L
L
L
D
H
Q
D
A
I
A
P
--
E
H
N
D
P
I
H
E
L
L
D
D
L
G
E
V
P
T
I
E
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
44
Fugue
43.83
14%
-190
- C- -
-
4CPC
-
SYCP3_HUMAN
A:
[81-223]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
N
K
A
L
L
A
K
R
K
R
L
E
M
Y
T
K
A
S
L
K
T
S
N
Q
K
I
E
H
V
W
K
T
Q
Q
D
Q
R
Q
K
L
N
Q
E
Y
S
Q
Q
F
L
T
L
F
Q
Q
W
D
L
D
M
Q
K
A
E
E
Q
E
E
K
I
L
N
M
F
R
Q
Q
Q
K
I
L
Q
Q
S
R
I
V
Q
S
Q
R
L
K
T
I
K
Q
L
Y
E
Q
F
I
K
S
M
E
E
L
E
K
N
H
D
N
L
L
T
G
A
Q
N
E
F
K
K
E
M
A
M
L
Q
K
K
I
M
M
E
T
Q
Q
Q
E
----------------------------------------------------
39
Fugue
42.60
19%
18
* C1 *
-
3FAY
1
A:
[3-381]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
S
K
E
K
R
E
K
L
E
A
Y
Q
H
L
F
Y
L
L
Q
T
N
P
T
Y
L
A
K
L
I
F
Q
M
P
Q
N
K
S
T
K
F
M
D
S
V
I
F
T
L
Y
N
Y
A
S
------
N
Q
R
E
E
Y
L
L
L
R
L
F
K
T
A
L
Q
E
E
I
K
S
K
V
D
Q
I
Q
E
I
V
T
G
N
P
T
V
I
K
M
V
V
S
F
N
R
G
-
A
R
G
Q
N
A
L
R
Q
I
L
A
P
V
V
K
E
I
M
D
D
K
-
S
L
N
I
K
T
D
P
V
D
I
Y
K
--------------------------------
S
W
V
N
Q
M
E
S
Q
T
GEASKLPYDVT
P
E
Q
A
L
AH
E
E
V
K
T
R
L
D
S
S
I
R
N
M
---
R
A
V
T
D
K
F
L
S
A
I
V
S
S
V
D
K
I
P
Y
G
M
R
F
I
A
K
V
L
K
D
S
L
H
E
K
F
P
D
A
G
E
---
D
-------
E
L
L
K
I
I
G
N
L
L
Y
Y
R
Y
M
N
-
P
A
I
V
A
P
D
A
F
D
I
I
------
D
L
----
S
A
G
G
Q
L
T
T
D
Q
R
R
N
L
G
S
I
A
K
M
L
Q
H
A
A
S
N
--
K
M
F
L
G
D
N
A
H
L
S
I
I
N
E
Y
L
S
Q
S
Y
Q
K
F
R
R
F
F
Q
T
A
C
D
----
V
P
E
L
Q
D
K
F
N
V
D
E
Y
S
D
L
V
TLT
K
P
V
I
Y
I
S
I
G
-----------
E
I
I
N
T
H
T
L
L
L
D
H
Q
D
A
I
A
P
--
E
H
N
D
P
I
H
E
L
L
D
D
L
G
E
V
P
T
I
E
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
HHSearch
34.19
10%
-18
* C3 *
-
4RJ9
-
GAP1_ORYSJ
A:
[6-158]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
G
L
V
K
V
R
V
V
R
G
V
N
L
A
V
RDLR----
S
---------------
S
D
P
Y
V
I
V
R
M
G
K
Q
------
K
L
K
T
R
V
I
K
K
T
T
N
P
E
W
N
D
E
L
T
L
S
I
E
D
P
----
A
V
P
V
R
L
E
V
Y
D
K
D
T
----
F
I
-
D
D
A
M
G
N
A
E
L
D
I
R
P
L
V
E
V
----
V
--
K
M
KIEGVADNTVV
K
K
V
V
P
N
RQNCLA
E
E
S
T
I
Y
I
SEG
K
V
K
Q
D
V
V
L
R
L
R
D
V
--------------
E
C
G
E
I
E
L
Q
L
Q
W
V
D
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
33.53
18%
35
- C3 -
-
1GMI
-
KPCE_RAT
A:
[4-133]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
N
G
L
L
K
I
K
I
C
E
A
V
S
L
K
P
--------
T
AWSLRDVGPRP
Q
T
F
L
L
D
P
Y
I
A
L
N
V
D
D
S
-----
R
I
G
Q
T
A
T
K
Q
K
T
N
S
P
A
W
H
D
E
F
V
T
D
V
C
N
-----
G
R
K
I
E
L
A
V
F
H
D
A
P
----
I
G
Y
D
D
F
V
A
N
C
T
I
Q
F
E
E
L
L
Q
N
GS--
R
--
H
-----------------------------------
F
--
E
D
W
I
D
L
E
P
----------------
E
G
K
V
Y
V
I
I
D
L
S
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
31.45
22%
-47
- C1 -
-
3FAY
1
A:
[227-381]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
I
I
G
N
L
L
Y
Y
R
Y
-
M
N
P
A
I
V
A
P
D
A
F
D
I
I
DLSAG
G
Q
L
----
T
T
----
D
Q
R
--
R
N
L
G
S
I
A
K
-
M
L
Q
H
A
A
S
N
K
M
-
F
L
G
D
N
A
H
L
S
I
I
N
E
Y
L
S
Q
S
Y
Q
K
F
R
R
F
F
Q
T
A
C
D
----
V
P
E
L
Q
D
K
F
N
V
D
E
Y
S
D
L
V
-----------
T
LT
K
P
V
I
Y
I
S
I
G
E
I
I
N
T
H
T
L
L
L
D
H
Q
D
A
I
A
P
--
E
H
N
D
P
I
H
E
L
L
D
D
L
G
E
V
P
T
I
E
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
31.13
17%
6
- C3 -
-
3B7Y
-
B:
[20-152]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
I
V
R
V
R
V
I
A
G
I
G
L
A
K
KDILG---
A
---------------
S
D
P
Y
V
R
V
T
L
Y
D
P
MNGVL
T
S
V
Q
T
K
T
I
K
K
S
L
N
P
K
W
N
E
E
I
L
F
R
V
H
P
Q
----
Q
H
R
L
L
F
E
V
F
D
E
N
R
----
L
T
R
D
D
F
L
G
Q
V
D
V
P
L
Y
P
L
P
T
E
----
N
P-
Y
-----------------------------------
T
--
F
K
D
F
V
L
H
P
R
S
---------
H
K
S
R
V
K
G
Y
L
R
L
K
M
T
Y
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
HHSearch
31.11
14%
38
- C3 -
-
2FK9
-
KPCL_HUMAN
A:
[7-137]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
F
N
G
Y
L
R
V
R
I
G
E
A
V
G
L
Q
P
--------
T
R
W
S
L
R
HSLFKKGHQL
L
D
P
Y
L
T
V
S
V
D
Q
V
-----
R
V
G
Q
T
S
T
K
Q
K
T
N
K
P
T
Y
N
E
E
F
C
A
N
V
T
D
G
-----
G
H
L
E
L
A
V
F
H
E
T
P
----
L
G
Y
D
H
F
V
A
N
C
T
L
Q
F
Q
E
L
L
R
T
T
GAS
D
--
T
-----------------------------------
F
--
E
G
W
V
D
L
E
P
----------------
E
G
K
V
F
V
V
I
T
L
T
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38
Fugue
30.18
65%
186
- C1 -
-
5JXC
-
SYGP1_MOUSE
A:
[7-92]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
R
L
D
R
E
Y
E
E
E
I
H
S
L
K
E
R
L
H
M
S
N
R
K
L
E
E
Y
E
R
R
L
L
S
Q
E
E
Q
T
S
K
I
L
M
Q
Y
Q
A
R
L
E
Q
S
E
K
R
L
R
Q
Q
Q
V
E
K
D
S
Q
I
K
S
I
I
G
R
L
M
L
V
E
E
E
L
R
R
D
H
-----------------------------------------------------------------------
19
HHSearch
30.18
65%
186
- C1 -
-
5JXC
-
SYGP1_MOUSE
A:
[7-92]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
R
L
D
R
E
Y
E
E
E
I
H
S
L
K
E
R
L
H
M
S
N
R
K
L
E
E
Y
E
R
R
L
L
S
Q
E
E
Q
T
S
K
I
L
M
Q
Y
Q
A
R
L
E
Q
S
E
K
R
L
R
Q
Q
Q
V
E
K
D
S
Q
I
K
S
I
I
G
R
L
M
L
V
E
E
E
L
R
R
D
H
-----------------------------------------------------------------------
4
PsiBlast_PDB
30.17
65%
186
- C1 -
-
5JXC
-
SYGP1_MOUSE
A:
[7-92]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
R
L
D
R
E
Y
E
E
E
I
H
S
L
K
E
R
L
H
M
S
N
R
K
L
E
E
Y
E
R
R
L
L
S
Q
E
E
Q
T
S
K
I
L
M
Q
Y
Q
A
R
L
E
Q
S
E
K
R
L
R
Q
Q
Q
V
E
K
D
S
Q
I
K
S
I
I
G
R
L
M
L
V
E
E
E
L
R
R
D
H
-----------------------------------------------------------------------
33
HHSearch
29.55
15%
6
- C3 -
-
1RLW
-
PA24A_HUMAN
A:
[3-122]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
K
F
T
V
V
V
L
R
A
T
K
V
T
K
G
A
F
G
D
M
L
D
T
---------------
P
D
P
Y
V
E
L
F
I
S
T
T
PD---
S
R
K
R
T
R
H
F
N
N
D
I
N
P
V
W
N
E
T
F
E
F
I
L
D
P
N
Q---
E
N
V
L
E
I
T
L
M
D
A
N
Y
----
V
-
M
D
E
T
L
G
T
A
T
F
T
V
S
S
M
K
V
G
----
E
--
K
-----------------------------------
K
--
E
V
P
F
I
F
N
Q
V
----------------
T
E
M
V
L
E
M
S
L
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
HHSearch
29.52
16%
33
- C3 -
-
2CJS
5
UN13A_RAT
A:
[10-158]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
G
I
L
S
L
L
C
V
G
V
K
K
A
K
F
--------
D
GAQEK----------
F
N
T
Y
V
T
L
K
V
Q
N
V
------
E
S
T
T
I
A
V
-
R
G
S
Q
P
S
W
E
Q
D
F
M
F
E
I
N
R
L
----
D
L
G
L
T
V
E
V
W
N
K
G
-----
L
I
W
D
T
M
V
G
T
V
W
I
P
L
R
T
I
R
Q
S
----
N
EE
G
-----------------------------------
P
--
G
E
W
L
T
L
D
S
Q
A
I
MADSEIC
G
T
K
D
P
T
F
H
R
I
L
L
D
A
H
F
E
L
P
L
D
I
P
E
E
E
A
R
Y
W
A
K
K
L
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
28.84
18%
40
- C3 -
-
2DMH
-
MYOF_HUMAN
A:
[7-133]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
M
L
R
V
I
V
E
S
A
S
N
I
P
K
--------
T
KFGK-----------
P
D
P
I
V
S
V
I
F
K
D
E
-----
K
-
K
K
T
K
K
V
D
N
E
L
N
P
V
W
N
E
I
L
E
F
D
L
R
G
I
P
L
D
F
S
S
S
L
G
I
I
V
K
D
F
E
T
----
I
G
Q
N
K
L
I
G
T
A
T
V
A
L
K
D
L
T
G
D
----
Q
--
S
-----------------------------------
R
--
S
L
P
Y
K
L
I
S
L
L
N
-------
E
K
G
Q
D
T
G
A
T
I
D
L
V
I
G
Y
D
P
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
HHSearch
28.83
17%
49
- C3 -
-
3PYC
-
SMUF1_HUMAN
A:
[5-132]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
K
I
R
L
T
V
L
C
A
K
N
L
A
K
--------
K
DFFRL----------
P
D
P
F
A
K
I
V
V
D
G
S
G----
Q
C
H
S
T
D
T
V
K
N
T
L
D
P
K
W
N
Q
H
Y
D
L
Y
V
G
K
-----
T
D
S
I
T
I
S
V
W
N
H
K
K
I
-
H
K
K
Q
G
A
G
F
L
G
C
V
R
L
L
S
N
A
I
S
R
L
K---
D
--
T
-----------------------------------
G
--
Y
Q
R
L
D
L
C
K
L
N
P
-------
S
D
T
D
A
V
R
G
Q
I
V
V
S
L
Q
T
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------