@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : STXB4_HUMAN: (2018-07-14 )
MNKNTSTVVSPSLLEKDPAFQMITIAKETGLGLKVLGGINRNEGPLVYIQEIIPGGDCYKDGRLKPGDQLVSVNKESMIGVSFEEAKSIITGAKLRLESAWEIAFIRQKSDNIQPENLSCTSLIEASGEYGPQASTLSLFSSPPEILIPKTSSTPKTNNDILSSCEIKTGYNKTVQIPITSENSTVGLSNTDVASAWTENYGLQEKISLNPSVRFKAEKLEMALNYLGIQPTKEQHQALRQQVQADSKGTVSFGDFVQVARNLFCLQLDEVNVGAHEISNILDSQLLPCDSSEADEMERLKCERDDALKEVNTLKEKLLESDKQRKQLTEELQNVKQEAKAVVEETRALRSRIHLAEAAQRQAHGMEMDYEEVIRLLEAKITELKAQLADYSDQNKESVQDLKKRIMVLDCQLRKSEMARKTFEASTEKLLHFVEAIQEVFSDNSTPLSNLSERRAVLASQTSLTPLGRNGRSIPATLALESKELVKSVRALLDMDCLPYGWEEAYTADGIKYFINHVTQTTSWIHPVMSVLNLSRSEENEEDCSRELPNQKS
Atome Classification :
(20 SA)
.........10.......-.20...----...------.-.30........---40-..--.-.---.-...50........60.........70........80.....--...90-.--........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MNKNTSTVV
S
P
S
L
LEKDP-A
F
Q
M
I
T
----
I
AK------E-TGL
G
L
K
V
L
GGI---NR-NE--G-
P
---
L
-
V
Y
I
QEIIPGGDCYK-DGRLKPGD
Q
L
V
SVNKE
S
M
IGV
S
F
E
E
A
--
K
S
I
I
--T--G
A
K
L
R
L
ES
A
W
E
I
A
F
I
RQKSDNIQPENL
S
C
T
S
L
I
E
ASGEYGPQA
S
T
L
S
LFSSPP
E
I
L
I
PKTSSTPKTNNDI
L
S
S
C
E
IKTGYN
K
T
V
Q
I
P
ITSEN
S
T
VGLSNT
D
V
A
S
A
W
T
ENYGLQ
E
K
I
SLNPS
V
R
F
K
A
E
K
L
E
M
A
L
N
Y
LGIQP
T
K
E
Q
H
Q
A
L
R
Q
Q
V
QADSKGTV
S
F
G
D
F
V
Q
V
A
R
N
L
F
C
L
Q
LDEVNV
G
A
H
E
I
S
N
I
L
D
S
QLLPCDSS
E
A
D
E
M
E
R
L
KCER
D
D
A
L
K
E
V
N
T
L
K
E
K
L
L
E
S
D
K
Q
R
K
Q
L
T
E
E
L
Q
N
V
K
Q
E
A
K
A
V
V
E
E
T
R
A
L
R
S
R
I
H
L
A
E
A
A
Q
R
QAHGMEM
D
Y
E
E
V
I
R
L
L
E
A
K
I
T
E
L
K
A
Q
L
ADYSDQ
N
K
E
S
V
Q
D
L
K
K
R
I
M
V
L
DCQL
R
K
S
E
M
A
R
K
T
F
E
A
S
T
E
K
L
L
H
F
V
E
A
I
Q
E
V
FSDNSTP
L
S
N
L
S
E
R
R
A
V
L
ASQTSLTPLGRNGRSI
P
A
T
LAL
E
S
K
E
L
V
K
S
V
R
A
L
LDMDCLPYGW
E
E
AYTA
D
G
I
K
Y
F
I
N
H
V
T
Q
T
T
S
W
I
H
P
V
M
S
V
L
NLSRSEE
N
E
E
D
C
S
R
ELPNQKS
1
PsiBlast_PDB
84.79
86%
-137
- C2 -
-
1WI4
-
STXB4_MOUSE
A:
[10-103]
-------------
L
D
R
D
P
-
A
F
R
V
I
T
----
V
T
K
------
E
-
T
G
L
G
L
K
I
L
G
G
I
---
N
R
-
N
E
--
G
-
P
---
L
-
V
Y
I
H
E
V
I
P
G
G
D
C
Y
K
-
D
G
R
L
K
P
G
D
Q
L
V
S
I
N
K
E
S
M
I
G
V
S
F
E
E
A
--
K
S
I
I
--
T
--
R
A
K
L
R
S
E
S
P
W
E
I
A
F
I
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
HHSearch
74.42
87%
-131
- C2 -
-
1WI4
-
STXB4_MOUSE
A:
[12-90]
---------------
R
D
P
-
A
F
R
V
I
T
----
V
T
K
------
E
-
T
G
L
G
L
K
I
L
G
G
I
---
N
R
-
N
E
--
G
-
P
---
L
-
V
Y
I
H
E
V
I
P
G
G
D
C
Y
K
-
D
G
R
L
K
P
G
D
Q
L
V
S
I
N
K
E
S
M
I
G
V
S
F
E
E
A
--
K
S
I
I
--
T
--
R
A
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
65.23
23%
-
- C2 -
-
2XKX
-
DLG4_RAT
A:
[135-279]
--
K
E
A
G
S
I
V
R
L
Y
V
M
R
R
K
P
-
P
A
E
K
V
M
E
I
K
L
I
K
G
------
P
-
K
G
L
G
F
S
I
A
G
G
V
---
G
N
-
Q
H
--
I
-
P
GDN
S
-
I
Y
V
T
K
I
I
E
G
G
A
A
H
K
-
D
G
R
L
Q
I
G
D
K
I
L
A
V
N
S
V
G
L
E
D
V
M
H
E
D
A
--
V
A
A
-----------
L
K
N
T
Y
D
V
V
Y
L
K
V
A
K
---------------------
P
S
N
A
Y
L
S
D
S
Y
A
P
P
D
I
---
T
T
S
Y
S
Q
H
L
D
N
E
I
S
H
S
S
Y
L
G
T
D
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
HHSearch
59.08
22%
-169
- C2 -
-
3TSZ
-
A:
[9-133]
-------------------
S
M
K
L
V
K
----
F
R
K
------
G
-
D
S
V
G
L
R
L
A
G
G
N
---
D
--------
V
---
G
-
I
F
V
A
G
V
L
E
D
S
P
A
A
K
-
E
G
-
L
E
E
G
D
Q
I
L
R
V
N
N
V
D
F
T
N
I
I
R
E
E
A
--
V
L
F
L
--
L
--
D
L
P
K
--
G
E
E
V
T
I
L
A
Q
K
K
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
52.46
43%
-27
- C2 -
-
5GLJ
-
PTN13_HUMAN
A:
[21-85]
-----------------------------------------
G
L
G
F
Q
I
I
G
G
E
---
K
M
-
G
R
--
L
-
D
---
L
G
I
F
I
S
S
V
A
P
G
G
P
A
D
L
-
D
G
C
L
K
P
G
D
R
L
I
S
V
N
S
V
S
L
E
G
V
S
H
H
A
A
--
I
E
I
L
--
Q
--
N
A
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
52.10
40%
-99
- C2 -
-
2DKR
-
A:
[15-79]
--------------------------------------
D
-
E
G
L
G
F
N
I
M
G
G
K
---
E
Q
-
N
S
--
P
-------
I
Y
I
S
R
V
I
P
G
G
V
A
D
R
-
H
G
G
L
K
R
G
D
Q
L
L
S
V
N
G
V
S
V
E
G
E
Q
H
E
K
A
--
V
E
L
L
--
K
--
A
A
Q
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
51
Fugue
51.81
24%
-25
- C2 -
-
1BE9
-
A:
[5-106]
-------
F
L
G
E
E
D
I
P
R
E
P
-
R
R
I
V
I
H
----
R
G
S
--------
T
G
L
G
F
N
I
I
G
G
E
----
D
------G
E
---
G
-
I
F
I
S
F
I
L
A
G
G
P
A
D
L
S
-
G
E
L
R
K
G
D
Q
I
L
S
V
N
G
V
D
L
R
N
A
S
H
E
Q
A
--
A
I
A
L
--
K
--
N
A
G
--
Q
T
V
T
I
I
A
Q
Y
K
P
E
E
Y
S
R
F
E
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
48
Fugue
51.36
17%
-113
- C2 -
-
1Q3O
-
SHAN1_RAT
A:
[3-106]
--
D
Y
I
I
K
E
K
T
V
L
L
Q
K
K
D
S
-
E
G
F
G
F
V
----
L
R
G
------
A
-
K
A
Q
T
P
I
E
E
F
T
P
---
T
P
-
A
F
--
P
-
A
---
L
-
Q
Y
L
E
S
V
D
E
G
G
V
A
W
R
-
A
G
-
L
R
M
G
D
F
L
I
E
V
N
G
Q
N
V
V
K
V
G
H
R
Q
V
--
V
N
M
I
--
R
Q
G
G
N
T
L
M
V
K
V
V
M
V
T
R
H
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
50.33
34%
-28
- C2 -
-
1UM1
-
A:
[19-96]
----------------------------------------
S
G
L
G
M
G
L
I
D
G
M
---
H
T
-
H
L
--
G
A
P
---
G
-
L
Y
I
Q
T
L
L
P
G
S
P
A
A
A
-
D
G
R
L
S
L
G
D
R
I
L
E
V
N
G
S
S
L
L
G
L
G
Y
L
R
A
--
V
D
L
I
--
R
H
G
G
K
K
M
R
--------
F
L
V
A
K
S
D
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
HHSearch
50.19
22%
-130
- C2 -
-
2EDP
-
SHRM4_HUMAN
A:
[10-92]
-----------------
F
-
Q
Y
V
P
V
Q
----
L
Q
G
------
G
-
A
P
W
G
F
T
L
K
G
G
L
---
E
H
-----
C
-
E
---
P
-
L
T
V
S
K
I
E
D
G
G
K
A
A
L
-
S
Q
K
M
R
T
G
D
E
L
V
N
I
N
G
T
P
L
Y
G
-
S
R
Q
E
A
--
L
I
L
I
--
K
--
G
S
F
R
----
I
L
K
L
I
V
R
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
HHSearch
48.70
27%
28
- C2 -
-
3EGH
1
NEB2_RAT
C:
[82-169]
---------------------
F
P
V
E
----
L
E
K
D-----
S
-
E
G
L
G
I
S
I
I
G
M
G
AGA
D
M
G
L
E
--
K
-
L
---
G
-
I
F
V
K
T
V
T
E
G
G
A
A
H
R
-
D
G
R
I
Q
V
N
D
L
L
V
E
V
D
G
T
S
L
V
G
V
T
Q
S
F
A
--
A
S
V
L
--
R
--
N
T
K
G
----
R
V
R
F
M
I
G
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
43
Fugue
48.52
20%
-24
- C2 -
-
2F5Y
-
RGS3_HUMAN
A:
[2-83]
-----------------
M
-
R
Y
R
Q
I
T
----
I
P
R
G-----
K
-
D
G
F
G
F
T
I
C
C
D
S
---
P
--------------
V
R
V
Q
A
V
D
S
G
G
P
A
E
R
-
A
G
-
L
Q
Q
L
D
T
V
L
Q
L
N
E
R
P
V
E
H
W
K
C
V
E
L
--
A
H
E
I
R
S
C
--
P
S
E
I
I
L
L
V
W
R
M
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
HHSearch
48.36
29%
-22
- C2 -
-
2D92
-
A:
[14-93]
-----------------
P
-
E
V
K
I
V
E
----
L
V
K
D
-----
C
-
K
G
L
G
F
S
I
L
D
Y
Q
---
D
P
-
L
D
PT
R
-
S
---
V
-
I
V
I
R
S
L
V
A
D
G
V
A
E
R
-
S
G
G
L
L
P
G
D
R
L
V
S
V
N
E
Y
C
L
D
N
T
S
L
A
E
A
--
V
E
I
L
--
K
--
A
V
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
49
Fugue
47.59
18%
-140
- C2 -
-
2OSG
-
ZO2_HUMAN
A:
[1-83]
-----------------------------
M
I
G
------
V
-
L
L
M
K
S
R
A
N
E
E
Y
---
G
L
-
R
L
--
G
-
S
---
Q
-
I
F
V
K
E
M
T
R
T
G
L
A
T
K
-
D
G
N
L
H
E
G
D
I
I
L
K
I
N
G
T
V
T
E
N
M
S
L
T
D
A
--
R
K
L
I
--
E
--
K
S
R
G
K
L
Q
----
L
V
V
L
R
D
S
L
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
46.83
37%
24
- C2 -
-
2BYG
-
DLG2_HUMAN
A:
[186-265]
--------------------
F
Q
S
M
T
----
V
V
E
I
K
L
F
K
G
P
-
K
G
L
G
F
S
I
A
G
G
V
---
G
N
-
Q
H
--
I
-
P
GDN
S
-
I
Y
V
T
K
I
I
D
G
G
A
A
Q
K
-
D
G
R
L
Q
V
G
D
R
L
L
M
V
N
N
Y
S
L
E
E
V
T
H
E
E
A
--
V
A
I
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
HHSearch
45.72
19%
-55
- C2 -
-
3R0H
-
INAD_DROME
A:
[8-108]
--------
E
P
A
T
A
E
I
K
P
N
-
K
K
I
L
I
E
----
L
K
V
E-----
K
-
K
P
M
G
V
I
V
C
G
G
K
---
N
N
-
H
V
--
T
-
T
---
G
-
C
V
I
T
H
V
Y
P
E
G
Q
V
A
A
-
D
K
R
L
K
I
F
D
H
I
C
D
I
N
G
T
P
I
H
V
G
S
M
T
T
L
K
V
H
Q
L
F
--
H
--
T
T
Y
E
---
K
A
V
T
L
T
V
F
R
A
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
45.35
19%
-56
- C2 -
-
3R0H
-
INAD_DROME
E:
[8-108]
--------
E
P
A
T
A
E
I
K
P
N
-
K
K
I
L
I
E
----
L
K
V
E-----
K
-
K
P
M
G
V
I
V
C
G
G
K
---
N
N
-
H
V
--
T
-
T
---
G
-
C
V
I
T
H
V
Y
P
E
G
Q
V
A
A
-
D
K
R
L
K
I
F
D
H
I
C
D
I
N
G
T
P
I
H
V
G
S
M
T
T
L
K
V
H
Q
L
F
--
H
--
T
T
Y
E
---
K
A
V
T
L
T
V
F
R
A
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
44.94
33%
-
- C2 -
-
3AXA
-
AFAD_MOUSE (first)
A:
[1-94]
-----------------
P
-
E
I
I
T
V
T
----
L
K
K
------
Q
-
N
G
M
G
L
S
I
V
A
A
K
---
G
A
-
G
Q
--
D
-
K
---
L
G
I
Y
V
K
S
V
V
K
G
G
A
A
D
V
-
D
G
R
L
A
A
G
D
Q
L
L
S
V
D
G
R
S
L
V
G
L
S
Q
E
R
A
--
A
E
L
M
T
R
T
--
S
S
V
V
T
L
E
V
A
K
Q
G
A
I
R
R
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
44.85
35%
-48
- C2 -
-
2AIN
-
A:
[2-78]
---------------
K
E
P
-
E
I
I
T
V
T
----
L
K
K
------
Q
-
N
G
M
G
L
S
I
V
A
A
K
---
G
A
-
G
Q
--
D
-
K
---
L
G
I
Y
V
K
S
V
V
K
G
G
A
A
D
V
-
D
G
R
L
A
A
G
D
Q
L
L
S
V
D
G
R
S
L
V
G
L
S
Q
E
R
A
--
A
E
L
M
--
T
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
46
Fugue
44.66
17%
37
- C2 -
-
3R0H
2
INAD_DROME
A:
[8-204]
---------
E
P
A
T
A
E
I
K
P
N
K
K
I
L
I
E
----
L
K
V
------
E
K
K
P
M
G
V
I
V
C
G
G
K
---
N
N
-
H
V
--
T
-
T
---
G
-
C
V
I
T
H
V
Y
P
E
G
Q
V
A
A
-
D
K
R
L
K
I
F
D
H
I
C
D
I
N
G
T
P
I
H
V
G
S
-
M
T
T
--
L
K
V
H
--
Q
--
L
F
H
T
T
Y
E
K
A
V
T
L
T
V
F
R
A
D
P
P
E
L
E
K
F
N
V
D
L
M
-------
K
K
A
G
K
E
L
G
L
S
L
S
P
N
E
I
G
C
T
I
A
D
L
I
Q
----
G
Q
Y
P
E
I
D
S
K
L
Q
R
G
D
----
I
I
T
K
F
N
G
D
A
L
E
G
L
P
F
Q
V
C
Y
A
L
F
K
G
A
N
G
K
V
S
M
E
V
T
R
P
K
P
T
L
R
T
E
A
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------