@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : TRI27_HUMAN: (2018-07-14 )
MASGSVAECLQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTAETNVSCPQCRETFPQRHMRPNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICVVCDRSREHRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQMEREKIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEEKQQQPTRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTEKMQSDMEKIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPERFNLFPCVLGSPCFIAGRHYWEVEVGDKAKWTIGVCEDSVCRKGGVTSAPQNGFWAVSLWYGKEYWALTSPMTALPLRTPLQRVGIFLDYDAGEVSFYNVTERCHTFTFSHATFCGPVRPYFSLSYSGGKSAAPLIICPMSGIDGFSGHVGNHGHSMETSP
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.....-..270.......280.......290.--......300.--...--...310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450..-..-.-..460.......470...-.--...-480-.......490.......500.......510.
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MAS
G
S
V
A
E
C
L
Q
QETT
C
P
V
C
L
Q
Y
FAE
P
M
M
LDCG
H
N
I
C
C
A
C
L
A
R
C
WGTAETNVS
C
P
Q
C
R
E
T
F
P
Q
RHMRPNR
H
L
A
N
V
T
Q
L
V
K
Q
L
RTERPSGPGGEM
G
V
C
E
K
HR
E
P
L
K
L
Y
CEEDQM
P
I
C
V
V
CDRSREHRGHSVL
P
L
E
E
A
V
E
G
F
K
E
Q
I
Q
N
Q
L
D
H
L
K
R
V
K
D
L
K
K
R
R
RAQ
G
E
Q
A
R
A
E
L
L
S
L
T
Q
M
E
R
E
K
I
V
W
E
F
E
Q
L
Y
H
S
L
K
E
H
E
Y
R
L
L
A
R
L
E
E
L
D
L
A
I
YNSING
A
I
T
Q
F
S
C
N
I
S
H
L
S
S
L
I
A
Q
L
E
E
K
Q
QQ
P
T
R
E
L
L
Q
D
I
G
D
T
L
S
R
A
E
RIRIPEPW-ITP
P
D
L
Q
E
K
I
H
I
F
A
Q
K
C
L
F
L
T
E
S
L
K
Q
--
F
T
E
K
M
Q
S
D
M
E
--
K
I
Q
--
E
L
R
EA
Q
L
Y
S
V
D
V
T
LDPDTAY
P
S
L
I
L
SD
N
L
R
Q
V
R
Y
S
Y
L
Q
QDLPDNPER
F
N
L
F
P
CVLGS
P
C
F
I
AG
R
H
Y
W
E
V
EVGDK
A
K
W
T
I
GVC
E
D
S
V
CRKGGVTSAPQNG
F
W
A
V
S
L
W
YG
K
E
Y
W
ALTSPMTALPLRT
P
L
Q
RV
G
I
F
L
DYDAG
E
V
S
F
Y
NVT
E
-
R
C
-
H
-
T
F
T
FSHATFCGPVR
P
Y
F
S
-
L
--SYS-GGK-SAA
P
L
I
I
C
PMSGIDGFSGHVGNHGHSMETSP
1
PsiBlast_PDB
81.19
43%
-46
- C3 -
-
4CG4
-
MEFV_HUMAN
A:
[9-366]
-------------------------------------------------------------------------------------------------------------------------------------------
K
K
K
I
Q
K
Q
L
E
H
L
K
K
L
R
K
S
G
E
E
Q
R
S
Y
G
E
E
K
A
V
S
F
L
K
Q
T
E
A
L
K
Q
R
V
Q
R
K
L
E
Q
V
Y
Y
F
L
E
Q
Q
E
H
F
F
V
A
S
L
E
D
V
G
Q
M
V
G
Q
I
R
K
A
Y
D
T
R
V
S
Q
D
I
A
L
L
D
A
L
I
G
E
L
E
A
K
E
C
Q
S
E
W
E
L
L
Q
D
I
G
D
I
L
H
R
A
K
T
V
P
V
P
E
K
W
-
T
T
P
Q
E
I
K
Q
K
I
Q
L
L
H
Q
K
S
E
F
V
E
K
S
T
K
Y
--
F
S
E
T
L
R
S
E
M
E
M
F
N
V
P
--
E
L
I
G
A
Q
A
H
A
V
N
V
I
L
D
A
E
T
A
Y
P
N
L
I
F
S
D
D
L
K
S
V
R
L
G
N
K
W
E
R
L
P
D
G
P
Q
R
F
D
S
C
I
I
V
L
G
S
P
S
F
L
S
G
R
R
Y
W
E
V
E
V
G
D
K
T
A
W
I
L
G
A
C
K
T
S
I
S
R
K
G
N
M
T
L
S
P
E
N
G
Y
W
V
V
I
M
M
K
E
N
E
Y
Q
A
S
S
V
P
P
T
R
L
L
I
K
E
P
P
K
R
V
G
I
F
V
D
Y
R
V
G
S
I
S
F
Y
N
V
T
A
-
R
S
-
H
-
I
Y
T
F
A
S
C
S
F
S
G
P
L
Q
P
I
F
S
P
G
--
T
R
D
-
G
G
K
-
N
T
A
P
L
T
I
C
P
V
G
G
-------------------
21
Fugue
80.27
41%
-40
- C3 -
-
4CG4
-
MEFV_HUMAN
A:
[2-377]
------------------------------------------------------------------------------------------------------------------------------------
S
E
V
A
L
E
H
K
K
K
I
Q
K
Q
L
E
H
L
K
K
L
R
K
S
G
E
E
Q
R
S
Y
G
E
E
K
A
V
S
F
L
K
Q
T
E
A
L
K
Q
R
V
Q
R
K
L
E
Q
V
Y
Y
F
L
E
Q
Q
E
H
F
F
V
A
S
L
E
D
V
G
Q
M
V
G
Q
I
R
K
A
Y
D
T
R
V
S
Q
D
I
A
L
L
D
A
L
I
G
E
L
E
A
K
E
C
Q
S
E
W
E
L
L
Q
D
I
G
D
I
L
H
R
A
K
T
V
P
V
P
E
K
W
-
T
T
P
Q
E
I
K
Q
K
I
Q
L
L
H
Q
K
S
E
F
V
E
K
S
T
K
Y
--
F
S
E
T
L
R
S
E
M
E
--
M
F
N
VP
E
L
I
G
A
Q
A
H
A
V
N
V
I
L
D
A
E
T
A
Y
P
N
L
I
F
S
D
D
L
K
S
V
R
L
G
N
K
W
E
R
L
P
D
G
P
Q
R
F
D
S
C
I
I
V
L
G
S
P
S
F
L
S
G
R
R
Y
W
E
V
E
V
G
D
K
T
A
W
I
L
G
A
C
K
T
S
I
S
R
K
G
N
M
T
L
S
P
E
N
G
Y
W
V
V
I
M
M
K
E
N
E
Y
Q
A
S
S
V
P
P
T
R
L
L
I
K
E
P
P
K
R
V
G
I
F
V
D
Y
R
V
G
S
I
S
F
Y
N
V
T
A
-
R
S
-
H
-
I
Y
T
F
A
S
C
S
F
S
G
P
L
Q
P
I
F
S
-
P
G-
T
R
D
-
G
G
K
-
N
T
A
P
L
T
I
C
P
V
G
G
--------
Q
G
P
D
A
L
E
V
L
F
Q
31
HHSearch
73.97
41%
-13
- C3 -
-
4CG4
2
MEFV_HUMAN
D:
[2-367]
------------------------------------------------------------------------------------------------------------------------------------
S
E
V
A
L
E
H
K
K
K
I
Q
K
Q
L
E
H
L
K
K
L
R
K
S
G
E
E
Q
R
S
Y
G
E
E
K
A
V
S
F
L
K
Q
T
E
A
L
K
Q
R
V
Q
R
K
L
E
Q
V
Y
Y
F
L
E
Q
Q
E
H
F
F
V
A
S
L
E
D
V
G
Q
M
V
G
Q
I
R
K
A
Y
D
T
R
V
S
Q
D
I
A
L
L
D
A
L
I
G
E
L
E
A
K
E
C
Q
S
E
W
E
L
L
Q
D
I
G
D
I
L
H
R
A
K
T
V
P
V
-
P
E
K
W
T
T
P
Q
E
I
K
Q
K
I
Q
L
L
H
Q
K
S
E
F
V
E
K
S
T
K
Y
FS
E
T
L
R
S
E
M
E
M
F
--
N
V
P
--
E
L
I
G
A
Q
A
H
A
V
N
V
I
L
D
A
E
T
A
Y
P
N
L
I
F
S
D
D
L
K
S
V
R
L
G
N
K
W
E
R
L
P
D
G
P
Q
R
F
D
S
C
I
I
V
L
G
S
P
S
F
L
S
G
R
R
Y
W
E
V
E
V
G
D
K
T
A
W
I
L
G
A
C
K
T
S
I
S
R
K
G
N
M
T
L
S
P
E
N
G
Y
W
V
V
I
M
M
K
E
N
E
Y
Q
A
S
S
V
P
P
T
R
L
L
I
K
E
P
P
K
R
V
G
I
F
V
D
Y
R
V
G
S
I
S
F
Y
N
V
T
A
-
R
S
-
H
-
I
Y
T
F
A
S
C
S
F
S
G
P
L
Q
P
I
F
S
-
P
--
G
T
R
-
D
G
G
K
N
T
A
P
L
T
I
C
P
V
G
G
Q
------------------
22
Fugue
70.77
51%
-119
- C3 -
-
2IWG
-
RO52_HUMAN
B:
[1-181]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
M
V
H
I
T
L
D
P
D
T
A
N
P
W
L
I
L
S
E
D
R
R
Q
V
R
L
G
D
T
Q
Q
S
I
P
G
N
E
E
R
F
D
S
Y
P
M
V
L
G
A
Q
H
F
H
S
G
K
H
Y
W
E
V
D
V
T
G
K
E
A
W
D
L
G
V
C
R
D
S
V
R
R
K
G
H
F
L
L
S
S
K
S
G
F
W
T
I
W
L
W
N
K
Q
K
Y
E
A
G
T
Y
P
Q
T
P
L
H
L
Q
V
P
P
C
Q
V
G
I
F
L
D
Y
E
A
G
M
V
S
F
Y
N
I
T
D
-
H
G
S
L
-
I
Y
S
F
S
E
C
A
F
T
G
P
L
R
P
F
F
S
-
P
G-
F
N
D
-
G
G
K
-
N
T
A
P
L
T
L
C
P
L
---------------------
3
PsiBlast_PDB
68.86
51%
-117
- C3 -
-
2IWG
-
RO52_HUMAN
B:
[3-181]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
H
I
T
L
D
P
D
T
A
N
P
W
L
I
L
S
E
D
R
R
Q
V
R
L
G
D
T
Q
Q
S
I
P
G
N
E
E
R
F
D
S
Y
P
M
V
L
G
A
Q
H
F
H
S
G
K
H
Y
W
E
V
D
V
T
G
K
E
A
W
D
L
G
V
C
R
D
S
V
R
R
K
G
H
F
L
L
S
S
K
S
G
F
W
T
I
W
L
W
N
K
Q
K
Y
E
A
G
T
Y
P
Q
T
P
L
H
L
Q
V
P
P
C
Q
V
G
I
F
L
D
Y
E
A
G
M
V
S
F
Y
N
I
T
D
-
H
G
-
S
L
I
Y
S
F
S
E
C
A
F
T
G
P
L
R
P
F
F
S
-
P
--
G
F
N
D
G
G
K
-
N
T
A
P
L
T
L
C
P
L
---------------------
2
PsiBlast_PDB
68.10
50%
-131
- C3 -
-
2WL1
3
A:
[1-190]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
V
P
--
E
L
I
G
A
Q
A
H
A
V
N
V
I
L
D
A
E
T
A
Y
P
N
L
I
F
S
D
D
L
K
S
V
R
L
G
N
K
W
E
R
L
P
D
G
P
Q
R
F
D
S
C
I
I
V
L
G
S
P
S
F
L
S
G
R
R
Y
W
E
V
E
V
G
D
K
T
A
W
I
L
G
A
C
K
T
S
I
S
R
K
G
N
M
T
L
S
P
E
N
G
Y
W
V
V
I
M
M
K
E
N
E
Y
Q
A
S
S
V
P
P
T
R
L
L
I
K
E
P
P
K
R
V
G
I
F
V
D
Y
R
V
G
S
I
S
F
Y
N
V
T
A
-
R
S
-
H
-
I
Y
T
F
A
S
C
S
F
S
G
P
L
Q
P
I
F
S
-
P
G-
T
R
D
-
G
G
K
-
N
T
A
P
L
T
I
C
P
V
---------------------
36
HHSearch
67.85
50%
-136
- C3 -
-
2WL1
2
A:
[7-190]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
A
Q
A
H
A
V
N
V
I
L
D
A
E
T
A
Y
P
N
L
I
F
S
D
D
L
K
S
V
R
L
G
N
K
W
E
R
L
P
D
G
P
Q
R
F
D
S
C
I
I
V
L
G
S
P
S
F
L
S
G
R
R
Y
W
E
V
E
V
G
D
K
T
A
W
I
L
G
A
C
K
T
S
I
S
R
K
G
N
M
T
L
S
P
E
N
G
Y
W
V
V
I
M
M
K
E
N
E
Y
Q
A
S
S
V
P
P
T
R
L
L
I
K
E
P
P
K
R
V
G
I
F
V
D
Y
R
V
G
S
I
S
F
Y
N
V
T
A
-
R
S
-
H
-
I
Y
T
F
A
S
C
S
F
S
G
P
L
Q
P
I
F
S
-
P
--
G
T
R
-
D
G
G
K
N
T
A
P
L
T
I
C
P
V
---------------------
39
HHSearch
67.26
49%
-141
- C3 -
-
5LYG
3
A:
[12-186]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
P
A
D
V
I
L
D
P
K
T
A
N
P
I
L
L
V
S
E
D
Q
R
S
V
Q
R
A
K
E
P
Q
D
L
P
D
N
P
E
R
F
N
W
H
Y
C
V
L
G
C
E
S
F
I
S
G
R
H
Y
W
E
V
E
V
G
D
R
K
E
W
H
I
G
V
C
S
K
N
V
Q
R
K
G
W
V
K
M
T
P
E
N
G
F
W
T
M
G
L
T
D
G
N
K
Y
R
T
L
T
E
P
R
T
N
L
K
L
P
K
P
P
K
K
V
G
V
F
L
D
Y
E
T
G
D
I
S
F
Y
N
A
V
D
-
G
S
-
H
-
I
H
T
F
L
D
V
S
F
S
E
A
L
Y
P
V
F
R
-
I
--
L
T
L
-
E
----
P
T
A
L
T
I
C
P
----------------------
35
HHSearch
67.14
51%
-115
- C3 -
-
2IWG
-
RO52_HUMAN
B:
[3-180]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
H
I
T
L
D
P
D
T
A
N
P
W
L
I
L
S
E
D
R
R
Q
V
R
L
G
D
T
Q
Q
S
I
P
G
N
E
E
R
F
D
S
Y
P
M
V
L
G
A
Q
H
F
H
S
G
K
H
Y
W
E
V
D
V
T
G
K
E
A
W
D
L
G
V
C
R
D
S
V
R
R
K
G
H
F
L
L
S
S
K
S
G
F
W
T
I
W
L
W
N
K
Q
K
Y
E
A
G
T
Y
P
Q
T
P
L
H
L
Q
V
P
P
C
Q
V
G
I
F
L
D
Y
E
A
G
M
V
S
F
Y
N
I
T
D
H
G
S
-
L
-
I
Y
S
F
S
E
C
A
F
T
G
P
L
R
P
F
F
S
-
P
--
G
F
N
-
D
G
G
K
N
T
A
P
L
T
L
C
P
----------------------
6
PsiBlast_PDB
67.13
47%
-134
- C3 -
-
5LYG
3
A:
[4-186]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
--
E
W
K
K
A
L
F
K
P
A
D
V
I
L
D
P
K
T
A
N
P
I
L
L
V
S
E
D
Q
R
S
V
Q
R
A
K
E
P
Q
D
L
P
D
N
P
E
R
F
N
W
H
Y
C
V
L
G
C
E
S
F
I
S
G
R
H
Y
W
E
V
E
V
G
D
R
K
E
W
H
I
G
V
C
S
K
N
V
Q
R
K
G
W
V
K
M
T
P
E
N
G
F
W
T
M
G
L
T
D
G
N
K
Y
R
T
L
T
E
P
R
T
N
L
K
L
P
K
P
P
K
K
V
G
V
F
L
D
Y
E
T
G
D
I
S
F
Y
N
A
V
D
-
G
S
-
H
-
I
H
T
F
L
D
V
S
F
S
E
A
L
Y
P
V
F
R
-
I
--
L
----
T
L
-
E
P
T
A
L
T
I
C
P
----------------------
9
PsiBlast_PDB
66.92
46%
-128
- C3 -
-
4N7U
2
A:
[2-187]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
--
A
Y
N
--
E
W
K
K
A
L
F
K
P
A
D
V
I
L
D
P
K
T
A
D
P
I
L
L
V
S
E
D
Q
R
S
V
E
R
A
K
E
P
Q
D
L
P
D
N
P
E
R
F
N
W
H
Y
C
V
L
G
C
E
S
F
I
S
G
R
H
Y
W
E
V
E
V
G
D
R
K
E
W
H
I
G
V
C
S
K
N
V
Q
R
K
G
W
V
K
M
T
P
E
N
G
F
W
T
M
G
L
T
D
G
N
K
Y
R
T
L
T
E
P
R
T
N
L
K
L
P
K
P
P
K
K
V
G
V
F
L
D
Y
E
T
G
D
I
S
F
Y
N
A
V
D
-
G
S
-
H
-
I
H
T
F
L
D
V
S
F
S
E
A
L
Y
P
V
F
R
-
I
--
L
----
T
L
-
E
P
T
A
L
T
I
C
P
----------------------
12
PsiBlast_PDB
66.47
40%
-146
- C3 -
-
2FBE
-
RFPLA_HUMAN
A:
[8-188]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
Q
V
D
M
T
F
D
V
D
T
A
N
N
Y
L
I
I
S
E
D
L
R
S
F
R
S
G
D
L
S
Q
N
R
K
E
Q
A
E
R
F
D
T
A
L
C
V
L
G
T
P
R
F
T
S
G
R
H
Y
W
E
V
D
V
G
T
S
Q
V
W
D
V
G
V
C
K
E
S
V
N
R
Q
G
K
I
E
L
S
S
E
H
G
F
L
T
V
G
C
R
E
G
K
V
F
A
A
S
T
V
P
M
T
P
L
W
V
S
P
Q
L
H
R
V
G
I
F
L
D
V
G
M
R
S
I
A
F
Y
N
V
S
D
-
G
C
-
H
-
I
Y
T
F
I
E
I
P
V
C
E
P
W
R
P
F
F
A
-
H
--
K
R
G
-
S
Q
D
-
D
Q
S
I
L
S
I
C
S
V
I
N
-------------------
7
PsiBlast_PDB
66.37
47%
-132
- C3 -
-
5LYK
1
A:
[4-186]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
--
E
W
K
K
A
L
F
K
P
A
D
V
I
L
D
P
K
T
A
N
P
I
L
L
V
S
E
D
Q
R
S
V
Q
R
A
K
E
P
Q
D
L
P
D
N
P
E
R
F
N
W
H
Y
C
V
L
G
C
E
S
F
I
S
G
R
H
Y
W
E
V
E
V
G
D
R
K
E
W
H
I
G
V
C
S
K
N
V
Q
R
K
G
W
V
K
M
T
P
E
N
G
F
W
T
M
G
L
T
D
G
N
K
Y
R
T
L
T
E
P
R
T
N
L
K
L
P
K
P
P
K
K
V
G
V
F
L
D
Y
E
T
G
D
I
S
F
Y
N
A
V
D
-
G
S
-
H
-
I
H
T
F
L
D
V
S
F
S
E
A
L
Y
P
V
F
R
-
I
--
L
----
T
L
-
E
P
T
A
L
T
I
C
P
----------------------
8
PsiBlast_PDB
66.17
46%
-129
- C3 -
-
4N7I
4
A:
[2-187]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
--
A
Y
N
--
E
W
K
K
A
L
F
K
P
A
D
V
I
L
D
P
K
T
A
D
P
I
L
L
V
S
E
D
Q
R
S
V
E
R
A
K
E
P
Q
D
L
P
D
N
P
E
R
F
N
W
H
Y
C
V
L
G
C
E
S
F
I
S
G
R
H
Y
W
E
V
E
V
G
D
R
K
E
W
H
I
G
V
C
S
K
N
V
Q
R
K
G
W
V
K
M
T
P
E
N
G
F
W
T
M
G
L
T
D
G
N
K
Y
R
T
L
T
E
P
R
T
N
L
K
L
P
K
P
P
K
K
V
G
V
F
L
D
Y
E
T
G
D
I
S
F
Y
N
A
V
D
-
G
S
-
H
-
I
H
T
F
L
D
V
S
F
S
E
A
L
Y
P
V
F
R
-
I
--
L
----
T
L
-
E
P
T
A
L
T
I
C
P
----------------------
38
HHSearch
65.03
49%
-138
- C3 -
-
4N7I
4
A:
[13-188]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
P
A
D
V
I
L
D
P
K
T
A
D
P
I
L
L
V
S
E
D
Q
R
S
V
E
R
A
K
E
P
Q
D
L
P
D
N
P
E
R
F
N
W
H
Y
C
V
L
G
C
E
S
F
I
S
G
R
H
Y
W
E
V
E
V
G
D
R
K
E
W
H
I
G
V
C
S
K
N
V
Q
R
K
G
W
V
K
M
T
P
E
N
G
F
W
T
M
G
L
T
D
G
N
K
Y
R
T
L
T
E
P
R
T
N
L
K
L
P
K
P
P
K
K
V
G
V
F
L
D
Y
E
T
G
D
I
S
F
Y
N
A
V
D
-
G
S
-
H
-
I
H
T
F
L
D
V
S
F
S
E
A
L
Y
P
V
F
R
-
I
--
L
T
L
-
E
----
P
T
A
L
T
I
C
P
A
---------------------
10
PsiBlast_PDB
63.99
49%
-122
- C3 -
-
3ZO0
-
B:
[3-180]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
H
I
T
L
D
R
N
T
A
N
S
W
L
I
I
S
K
D
R
R
Q
V
R
M
G
D
T
H
Q
N
V
S
D
N
K
E
R
F
S
N
Y
P
M
V
L
G
A
Q
R
F
S
S
G
K
M
Y
W
E
V
D
V
T
Q
K
E
A
W
D
L
G
V
C
R
D
S
V
Q
R
K
G
Q
F
S
L
S
P
E
N
G
F
W
T
I
W
L
W
Q
-
K
S
Y
E
A
G
T
S
P
Q
T
T
L
H
I
Q
V
P
P
C
Q
I
G
I
F
V
D
Y
E
A
G
V
V
S
F
Y
N
I
T
D
-
H
G
-
S
L
I
Y
T
F
S
E
C
V
F
A
G
P
L
R
P
F
F
N
-
V
GF
N
Y
S
-
G
G
--
N
A
A
P
L
K
L
C
P
L
---------------------
11
PsiBlast_PDB
63.74
48%
-120
- C3 -
-
2VOK
-
RO52_MOUSE
A:
[15-192]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
H
I
T
L
D
R
N
T
A
N
S
W
L
I
I
S
K
D
R
R
Q
V
R
M
G
D
T
H
Q
N
V
S
D
N
K
E
R
F
S
N
Y
P
M
V
L
G
A
Q
R
F
S
S
G
K
M
Y
W
E
V
D
V
T
Q
K
E
A
W
D
L
G
V
C
R
D
S
V
Q
R
K
G
Q
F
S
L
S
P
E
N
G
F
W
T
I
W
L
W
Q
-
D
S
Y
E
A
G
T
S
P
Q
T
T
L
H
I
Q
V
P
P
C
Q
I
G
I
F
V
D
Y
E
A
G
V
V
S
F
Y
N
I
T
D
-
H
G
-
S
L
I
Y
T
F
S
E
C
V
F
A
G
P
L
R
P
F
F
N
-
V
GF
N
Y
S
-
G
G
--
N
A
A
P
L
K
L
C
P
L
---------------------
34
HHSearch
63.57
47%
-121
- C3 -
-
2VOK
-
RO52_MOUSE
A:
[14-192]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
V
H
I
T
L
D
R
N
T
A
N
S
W
L
I
I
S
K
D
R
R
Q
V
R
M
G
D
T
H
Q
N
V
S
D
N
K
E
R
F
S
N
Y
P
M
V
L
G
A
Q
R
F
S
S
G
K
M
Y
W
E
V
D
V
T
Q
K
E
A
W
D
L
G
V
C
R
D
S
V
Q
R
K
G
Q
F
S
L
S
P
E
N
G
F
W
T
I
W
L
W
Q
D
-
S
Y
E
A
G
T
S
P
Q
T
T
L
H
I
Q
V
P
P
C
Q
I
G
I
F
V
D
Y
E
A
G
V
V
S
F
Y
N
I
T
D
H
G
S
-
L
-
I
Y
T
F
S
E
C
V
F
A
G
P
L
R
P
F
F
N
-
V
--
G
F
N
-
Y
S
G
G
N
A
A
P
L
K
L
C
P
L
---------------------
4
PsiBlast_PDB
63.47
47%
-134
- C3 -
-
5HM7
4
BT3A1_HUMAN
A:
[62-243]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
W
K
K
A
L
F
K
P
A
D
V
I
L
D
P
K
T
A
N
P
I
L
L
V
S
E
D
Q
R
S
V
Q
R
A
K
E
P
Q
D
L
P
D
N
P
E
R
F
N
W
H
Y
C
V
L
G
C
E
S
F
I
S
G
R
H
Y
W
E
V
E
V
G
D
R
K
E
W
H
I
G
V
C
S
K
N
V
Q
R
K
G
W
V
K
M
T
P
E
N
G
F
W
T
M
G
L
T
D
G
N
K
Y
R
T
L
T
E
P
R
T
N
L
K
L
P
K
P
P
K
K
V
G
V
F
L
D
Y
E
T
G
D
I
S
F
Y
N
A
V
D
-
G
S
-
H
-
I
H
T
F
L
D
V
S
F
S
E
A
L
Y
P
V
F
R
-
I
--
L
----
T
L
-
E
P
T
A
L
T
I
C
P
----------------------
5
PsiBlast_PDB
62.90
49%
-135
- C3 -
-
4V1P
-
A:
[23-193]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
--
E
W
K
K
A
L
F
K
P
A
D
V
I
L
D
P
K
T
A
N
P
I
L
L
V
S
E
D
Q
R
S
V
Q
R
A
K
E
P
Q
D
L
P
D
N
P
E
R
F
N
W
H
Y
C
V
L
G
C
E
S
F
I
S
G
R
H
Y
W
E
V
E
V
G
D
R
K
E
W
H
I
G
V
C
S
K
N
V
Q
R
K
G
W
V
K
M
T
P
E
N
G
F
W
T
M
G
L
T
D
G
N
K
Y
R
T
L
T
E
P
R
T
N
L
K
L
P
K
P
P
K
K
V
G
V
F
L
D
Y
E
T
G
D
I
S
F
Y
N
A
V
D
-
G
S
-
H
-
I
H
T
F
L
D
V
S
F
S
E
A
L
Y
P
V
F
R
-
I
-----------------------------------------