@TOME V2.3
(Mar 2018)
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : UTS2_HUMAN: (2018-07-14 )
MYKLASCCLLFIGFLNPLLSLPLLDSREISFQLSAPHEDARLTPEELERASLLQILPEMLGAERGDILRKADSSTNIFNPRGNLRKFQDFSGQDPNILLSHLLARIWKPYKKRETPDCFWKYCV
Atome Classification :
(20 SA)
-------------------------------------.-...-.....10........20--.........30..-..-....40........50.....-------...60........70.....--...80....-----....90-..---......100.......110.......120..----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
-------------------------------------M-Y
K
L
-
A
S
C
C
L
L
F
I
G
F
L
N
P
L
LS---LPLLDSR
E
I
S
F
Q
L-SA-PHEDARL
T
P
E
E
L
E
R
A
S
L
L
Q
I
L
-------
P
E
M
LGAE
R
G
D
I
L
RKADSSTN--IFNPRGNL
R
-----
K
F
QDFS-GQ---
D
P
N
I
L
L
S
H
L
L
A
R
I
W
K
P
Y
KKRE
T
P
D
C
F
W
KYCV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38
Fugue
55.29
26%
36
- C12 -
-
4RHO
1
?
A:
[4-259]
---DKIHHHHHHEN
L
Y
F
Q
G
M
E
I
K
A
M
F
R
D
VSLSSRN
F
S
E
M
L
S
R
-
E
S
K
V
V
A
A
L
A
A
K
S
P
L
---------------------M
A
H
A
N
W
R
L
K
G
N
S
L
E
E
A
T
L
Y
P
A
F
DADGSPS
T
P
A
L
A
V
L
N
E
E
Q
R
G
K
K
H
S
A
S
H
AA
I
W
N
--
G
N
T
R
-----
P
N
E
G
A
S
M
S
C
H
V
S
D
E
K
V
L
P
D
R
F
S
T
R
L
-------
G
V
P
D
C
Y
A
K
S
Q
D
L
A
D
V
V
T
T
I
V
A
A
FNPL
V
V
E
A
S
P
EGYFDKQVFDDKPGVGW
M
L
Y
L
PKVITQQQVPEAR
A
L
I
P
V
S
A
KGKQT
G
T
I
I
V
SVTDAPFSVDN
P
E
H
V
A
I
A
N
R
I
E
I
R
L
V
D
Q
DLLPAYVDI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
Fugue
54.73
24%
17
- C12 -
-
4RIC
-
FAN1_HUMAN
A:
[1-631]
TGHP
Y
Y
L
R
S
F
L
V
V
L
K
T
V
L
E
N
E
D
D
M
L
L
F
D
E
Q
E
K
G
I
V
T
K
F
-
Y
Q
L
S
A
T
G
Q
K
L
Y
V
R
L
F
Q
R
K
L
S
W
I
K
M
T
K
L
E
Y
E
E
I
A
L
D
L
-
T
P
-
V
I
E
E
L
T
N
-
A
G
F
L
Q
T
E
S
E
L
Q
E
L
-------
S
E
V
L
E
L
L
S
A
P
E
L
K
S
L
A
K
T
F
H
--
L
V
N
P
N
G
Q
K
Q
-----
Q
L
V
D
A
F
-
L
K
---
L
A
K
Q
R
-
S
V
I
G
A
V
I
L
K
R
A
K
A
L
A
G
Q
--
S
V
R
I
C
K
G
P
R
A
V
F
S
R
I
L
L
L
F
S
LTDSMEDEDAACGGQGQLS
T
V
L
L
V
NLGR
M
E
F
P
S
Y
T
I
N
R
K
T
HIFQD
R
D
D
L
I
R
Y
A
A
A
T
H
M
L
S
D
I
S
S
A
M
A
N
GN
W
E
E
A
K
E
L
A
Q
C
A
K
R
D
W
N
R
L
KNH
P
S
L
R
C
H
E
D
LP
L
F
L
R
C
F
T
V
G
W
I
Y
T
R
I
L
S
R
F
V
E
I
L
Q
R
L
HM
Y
E
E
A
V
R
E
L
E
S
L
L
S
Q
RIYCPDS
R
G
R
W
W
D
R
L
A
L
N
L
H
QHLKR
L
E
P
T
I
K
C
I
T
E
G
L
A
DPEVRT
G
H
R
L
S
L
Y
Q
R
A
V
R
L
R
E
SPSCKKFKHLFQQLPEM
A
V
Q
D
V
K
H
V
T
I
T
G
R
L
CK
S
V
F
V
MVLCS
V
E
E
L
A
L
A
H
Y
R
R
S
GFDQGIHGE
G
S
T
F
S
T
L
Y
G
L
L
L
W
DIIFMDGIPDVFRNACQAFPLDLCTDS
F
F
T
S
R
R
P
A
L
E
A
R
L
Q
L
I
H
D
AP
E
E
S
L
R
A
W
V
A
A
T
W
H
E
Q
EGRVASLVSWDRFTS
L
Q
Q
A
Q
D
L
V
S
C
L
G
G
P
V
L
S
G
V
C
R
H
L
A
A
DFRHCRGGLPD
L
V
V
W
N
SQSR
H
F
K
L
V
E
V
K
G
PNDRLS
H
K
Q
M
I
W
L
A
E
L
Q
K
L
G
A
E
V
E
V
C
H
V
V
A
V
7
PsiBlast_PDB
51.76
32%
-79
- C10 -
-
5A9W
-
TYPA_ECOLI
A:
[382-436]
---------------------------------------------------------
V
S
---
R
P
K
V
I
F
R
E
I
D
G
R
K
-
Q
E
-
P
Y
E
N
V
T
L
D
V
E
E
Q
H
Q
G
S
V
M
Q
-----------
A
L
G
E
R
K
G
D
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
50.95
32%
-96
- C10 -
-
4ZCM
-
TYPA_ECOLI
A:
[416-476]
---------------------------------------------------------
V
S
---
R
P
K
V
I
F
R
E
I
D
G
R
K
-
Q
E
-
P
Y
E
N
V
T
L
D
V
E
E
Q
H
Q
G
S
V
M
Q
-----------
A
L
G
E
R
K
G
D
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
50.94
32%
-59
- C10 -
-
4ZCI
-
TYPA_ECOLI
A:
[416-476]
---------------------------------------------------------
V
S
---
R
P
K
V
I
F
R
E
I
D
G
R
K
-
Q
E
-
P
Y
E
N
V
T
L
D
V
E
E
Q
H
Q
G
S
V
M
Q
-----------
A
L
G
E
R
K
G
D
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
50.82
36%
-253
- C10 -
-
1X9Z
-
MUTL_ECOLI
A:
[85-117]
----------------------------------------------------------------------
I
D
F
Q
S
-
D
A
-
Q
H
V
T
I
R
A
V
P
L
P
L
R
Q
Q
N
L
Q
I
L
I
-------
P
E
L
I
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
50.61
32%
-80
- C10 -
-
5A9Y
-
TYPA_ECOLI
A:
[382-440]
---------------------------------------------------------
V
S
---
R
P
K
V
I
F
R
E
I
D
G
R
K
-
Q
E
-
P
Y
E
N
V
T
L
D
V
E
E
Q
H
Q
G
S
V
M
Q
-----------
A
L
G
E
R
K
G
D
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
50.27
32%
-74
- C10 -
-
4ZCL
-
TYPA_ECOLI
A:
[416-476]
---------------------------------------------------------
V
S
---
R
P
K
V
I
F
R
E
I
D
G
R
K
-
Q
E
-
P
Y
E
N
V
T
L
D
V
E
E
Q
H
Q
G
S
V
M
Q
-----------
A
L
G
E
R
K
G
D
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
49.96
30%
0
- C- -
-
1M0W
-
GSHB_YEAST
A:
[158-212]
----------------------------------------------------------------------------------------------------------------
S
E
K
V
D
R
L
H
S
Y
L
N
R
A
N
--
K
Y
D
P
K
G
P
I
Y
-----
N
D
Q
N
M
V
-
I
S
---
D
S
G
Y
L
L
S
K
A
L
A
K
A
V
E
S
Y
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
49.62
34%
-47
- C10 -
-
4ZCK
-
A:
[111-154]
---------------------------------------------------------
V
S
---
R
P
K
V
I
F
R
E
I
D
G
R
K
-
Q
E
-
P
Y
E
N
V
T
L
D
V
E
E
Q
H
Q
G
S
V
M
Q
A
L
-------
G
E
R
K
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
48.25
32%
-61
- C10 -
-
5A9X
-
TYPA_ECOLI
A:
[382-443]
---------------------------------------------------------
V
S
---
R
P
K
V
I
F
R
E
I
D
G
R
K
-
Q
E
-
P
Y
E
N
V
T
L
D
V
E
E
Q
H
Q
G
S
V
M
Q
-----------
A
L
G
E
R
K
G
D
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
47.74
32%
-35
- C10 -
-
5A9V
-
?
A:
[382-440]
---------------------------------------------------------
V
S
---
R
P
K
V
I
F
R
E
I
D
G
R
K
-
Q
E
-
P
Y
E
N
V
T
L
D
V
E
E
Q
H
Q
G
S
V
M
Q
-----------
A
L
G
E
R
K
G
D
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
41.88
34%
18
* C11 *
-
5K8R
-
PCDGF_HUMAN
A:
[8-62]
---------------------------------------------------------------------------------------
P
E
E
L
D
R
G
S
L
V
G
N
L
-------
A
K
D
L
G
F
G
V
G
D
L
--------------
P
T
R
N
L
R
V
I
A
EK
K
F
F
T
V
S
-
P
E
---
N
G
N
L
L
V
S
D
R
I
D
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
41.83
50%
-240
- C10 -
-
5O5E
-
?
A:
[104-124]
-----------------------------------------
L
-
A
I
C
C
M
I
F
L
G
F
A
D
D
V
L
N
---
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
HHSearch
41.71
50%
-204
- C7 -
-
5T4R
-
?
A:
[24-29]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
M
K
Y
C
A
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
40.54
50%
-213
- C10 -
-
6BW5
2
?
A:
[103-132]
-----------------------------------------
L
-
A
I
C
C
M
I
F
L
G
F
A
D
D
V
L
N
---
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
39.31
41%
-56
- C10 -
-
2KDD
-
BOREA_HUMAN
A:
[224-260]
-------------------------------------------------------------------
S
K
E
I
F
L
T
V
P
V
G
-
G
G
E
S
L
R
L
L
A
S
D
L
Q
R
H
S
I
A
Q
L
D
-------
P
E
A
L
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
Fugue
37.53
25%
-120
* C10 *
-
3PCQ
-
PSAM_THEEB
M:
[1-31]
-----------------------------------------------------------------------------------
M
A
L
T
D
T
Q
V
Y
V
A
L
V
I
A
L
L
-------
P
A
V
L
A
F
R
L
S
T
E
L
Y
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
36.47
50%
-137
- C10 -
-
6BW6
2
?
A:
[103-137]
-----------------------------------------
L
-
A
I
C
C
M
I
F
L
G
F
A
D
D
V
L
N
---
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
35.28
40%
17
- C10 -
-
4CPD
1
?
A:
[203-237]
---------------------------------------------------------------------------------------
P
E
R
L
E
R
A
A
S
L
G
A
I
-------
P
--
I
N
A
E
Q
E
N
P
V
R
R
V
R
S
E
T
N
--
D
E
G
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------