@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : spr0004: (2017-12-13 )
MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMVEVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVHVVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKDKESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVVSEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDKLTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYEDLVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV
Atome Classification :
(20 SA)
-------.........10........20.....-.-..30........40....-....50....------....60----........70........80........90....-....100.......110.......120.......130.......140.......150..----.....----160----.........-170....-...180..-......190.......200....-...210...-....220.-......230.....--..240-...-......250.......260.....-..270....---------...280.......290.....----..300.-......310.......320.......330.......340.......350.......360.......370
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
-------MALTAGIVGLPNV
G
K
S
T
L
F
N
A
I
T
KAG-A-EAANYP
F
A
TIDPNV
G
M
V
E-V
P
D
E
R
L
Q
K
L
T
------
E
MITPK----KTVP
T
T
F
E
F
T
D
I
A
G
I
VKGASKGEGL
G
N
K
F
L
A
N
I
R
-
E
V
D
A
I
V
H
V
V
R
AFD
D
E
N
V
M
R
E
QGREDAFVDPLADI
D
T
I
N
L
E
L
I
L
A
D
L
E
S
V
N
K
R
Y
A
R
V
E
K
M
----
A
R
T
Q
K
----
D
------
K
E
S
V
A
E
F
N
V
-
L
Q
K
I
K
P
V
-
L
EDG-KS
A
-
R
T
I
EFT
D
E
E
Q
K
V
V
K
G
L
F
L
LTTK
P
-
V
L
Y
V
ANV
D
E
-
D
VVSEPD
S
-
I
D
Y
V
K
Q
I
R
E
F
AATE--NA
E
---
V
V
V
-
I
SAR
A
E
E
E
I
S
ELD
D
E
D
K
K
E
F
L
E
A
I-GL
T
E
S
G
V
D
K
---------
L
T
R
A
A
Y
H
L
LGLGTYFTAGE
K
E
----
V
R
A
W
T
F
-KRGMKAPQAAG
I
I
H
S
D
F
E
K
G
F
I
R
A
V
TM
S
Y
E
D
L
V
K
YG
S
E
K
A
V
K
E
A
G
R
L
R
E
E
G
K
E
Y
IVQDG
D
I
M
E
F
R
FNV
74
HHSearch
91.01
57%
-107
- C5 -
-
1JAL
-
YCHF_HAEIN
A:
[2-363]
--------
G
F
K
C
G
I
V
G
L
P
N
V
G
K
S
T
L
F
N
A
L
T
K
A
G
--------
P
F
C
T
I
E
P
N
T
G
V
V
P
-
M
P
D
P
R
L
D
A
L
A
------
E
I
V
K
P
E
----
R
I
L
P
T
T
M
E
F
V
D
I
A
G
L
V
A
G
A
S
K
G
E
G
L
G
N
K
F
L
A
N
I
R
-
E
T
D
A
I
G
H
V
V
R
C
F
E
N
-------------
I
D
P
L
D
D
I
D
T
I
N
T
E
L
A
L
A
D
L
D
S
C
E
R
A
I
Q
R
L
Q
K
R
----
A
K
G
-
G
----
D
------
K
E
A
K
F
E
L
S
V
-
M
E
K
I
L
P
V
-
L
E
N
A
-
G
M
I
-
R
S
V
G
L
D
K
E
E
L
Q
A
I
K
S
Y
N
F
L
T
L
K
P
-
T
M
Y
I
A
N
V
N
E
-
D
G
F
E
N
-
N
---
P
Y
L
D
R
V
R
E
I
A
A
K
E
--
G
A
V
---
V
V
P
-
V
C
A
A
I
E
S
E
I
A
E
L
D
D
E
E
K
V
E
F
L
Q
D
L
-
G
I
E
E
P
G
L
N
R
---------
V
I
R
A
G
Y
A
L
L
N
L
Q
T
Y
F
T
A
G
V
K
E
----
V
R
A
W
T
V
-
S
V
G
A
T
A
P
K
A
A
A
V
I
H
T
D
F
E
K
G
F
I
R
A
E
V
I
A
Y
E
D
F
I
Q
F
N
G
E
N
G
A
K
E
A
G
K
W
R
L
E
G
K
D
Y
I
V
Q
D
G
D
V
M
H
F
R
F
N
V
1
PsiBlast_PDB
90.38
55%
-109
- C5 -
-
1JAL
-
YCHF_HAEIN
A:
[1-363]
-------
M
G
F
K
C
G
I
V
G
L
P
N
V
G
K
S
T
L
F
N
A
L
T
K
A
G
--------
P
F
C
T
I
E
P
N
T
G
V
V
P
-
M
P
D
P
R
L
D
A
L
A
------
E
I
V
K
P
E
----
R
I
L
P
T
T
M
E
F
V
D
I
A
G
L
V
A
G
A
S
K
G
E
G
L
G
N
K
F
L
A
N
I
R
-
E
T
D
A
I
G
H
V
V
R
C
F
E
N
-------------
I
D
P
L
D
D
I
D
T
I
N
T
E
L
A
L
A
D
L
D
S
C
E
R
A
I
Q
R
L
Q
K
R
----
A
K
G
-
G
----
D
------
K
E
A
K
F
E
L
S
V
-
M
E
K
I
L
P
V
-
L
E
N
A
-
G
M
I
-
R
S
V
G
L
D
K
E
E
L
Q
A
I
K
S
Y
N
F
L
T
L
K
P
-
T
M
Y
I
A
N
V
N
E
-
D
G
F
---
E
N
-
N
P
Y
L
D
R
V
R
E
I
A
A
K
E
--
G
A
V
---
V
V
P
-
V
C
A
A
I
E
S
E
I
A
E
L
D
D
E
E
K
V
E
F
L
Q
D
L
-
G
I
E
E
P
G
L
N
R
---------
V
I
R
A
G
Y
A
L
L
N
L
Q
T
Y
F
T
A
G
V
K
E
----
V
R
A
W
T
V
-
S
V
G
A
T
A
P
K
A
A
A
V
I
H
T
D
F
E
K
G
F
I
R
A
E
V
I
A
Y
E
D
F
I
Q
F
N
G
E
N
G
A
K
E
A
G
K
W
R
L
E
G
K
D
Y
I
V
Q
D
G
D
V
M
H
F
R
F
N
V
76
HHSearch
80.16
53%
-2
- C5 -
-
2DBY
4
?
A:
[1-366]
--------
M
L
A
V
G
I
V
G
L
P
N
V
G
K
S
T
L
F
N
A
L
T
R
A
N
-
A
-
L
A
A
N
Y
P
F
A
T
I
D
K
N
V
G
V
V
P
-
L
E
D
E
R
L
Y
A
L
Q
------
R
T
F
A
K
G
E
R
V
P
P
V
V
P
T
H
V
E
F
V
D
I
A
G
L
V
K
G
A
H
K
G
E
G
L
G
N
Q
F
L
A
H
I
R
-
E
V
A
A
I
A
H
V
L
R
C
F
P
D
P
---------------
L
E
D
A
E
V
V
E
T
E
L
L
L
A
D
L
A
T
L
E
R
R
L
E
R
L
R
K
E
----
A
R
A
------
D
------
R
E
R
L
P
L
L
E
A
-
A
E
G
L
Y
V
H
-
L
Q
E
G
-
K
P
A
-
R
T
F
P
P
S
E
A
V
A
R
F
L
K
E
T
P
L
L
T
A
K
P
-
V
I
Y
V
A
N
V
A
E
-
E
D
L
P
D
-
G
R
G
N
P
Q
V
E
A
V
R
R
K
A
L
E
E
--
G
A
E
---
V
V
V
-
V
S
A
R
L
E
A
E
L
A
E
L
S
G
E
E
A
R
E
L
L
A
A
Y
-
G
L
Q
E
S
G
L
Q
R
---------
L
A
R
A
G
Y
R
A
L
D
L
L
T
F
F
T
A
G
E
K
E
----
V
R
A
W
T
V
-
R
R
G
T
K
A
P
R
A
A
G
E
I
H
S
D
M
E
R
G
F
I
R
A
E
V
I
P
W
D
K
L
V
E
A
G
G
W
A
R
A
K
E
R
G
W
V
R
L
E
G
K
D
Y
E
V
Q
D
G
D
V
I
Y
V
L
F
--
4
PsiBlast_PDB
78.99
42%
-65
- C5 -
-
5EE1
-
OLA1_ORYSJ
A:
[25-387]
---------
L
K
I
G
I
V
G
L
P
N
V
G
K
S
T
F
F
N
I
V
T
K
L
S
-
I
-
P
A
E
N
F
P
F
C
T
I
D
P
N
E
A
R
V
Y
-
V
P
D
E
R
F
D
W
L
C
------
Q
L
Y
K
P
K
----
S
E
V
S
A
Y
L
E
I
N
D
I
A
G
L
V
R
--
H
A
G
E
G
L
G
N
A
F
L
S
H
I
R
-
A
V
D
G
I
F
H
V
L
R
A
F
E
D
------------
S
V
D
P
V
R
D
L
E
T
I
G
E
E
L
R
L
K
D
I
E
F
V
Q
N
K
I
D
D
L
E
K
S
----
M
K
R
S
N
----
D
------
K
Q
L
K
L
E
H
E
L
-
C
E
K
V
K
A
H
-
L
E
D
G
-
K
D
V
-
R
F
G
D
W
K
S
A
D
I
E
I
L
N
T
F
Q
L
L
T
A
K
P
-
V
V
Y
L
V
N
M
S
E
-
K
D
Y
Q
R
K
K
N
--
K
F
L
P
K
I
H
A
W
V
Q
E
H
--
G
G
E
---
T
I
I
P
F
S
C
A
F
E
R
L
L
A
D
M
P
P
D
E
A
A
K
Y
C
-
A
E
-
N
Q
I
A
S
V
I
P
K
---------
I
I
K
T
G
F
A
A
I
H
L
I
Y
F
F
T
A
G
P
D
E
----
V
K
C
W
Q
I
-
R
R
Q
T
K
A
P
Q
A
A
G
T
I
H
T
D
F
E
R
G
F
I
C
A
E
V
M
K
F
D
D
L
K
E
L
G
S
E
S
A
V
K
A
A
G
K
Y
R
Q
E
G
K
T
Y
V
V
Q
D
G
D
I
I
F
F
K
F
N
-
21
PsiBlast_CBE
78.06
42%
-67
- C5 -
-
5EE9
1
OLA1_ORYSJ
B:
[26-388]
---------
L
K
I
G
I
V
G
L
P
N
V
G
K
S
T
F
F
N
I
V
T
K
L
S
-
I
-
P
A
E
N
F
P
F
C
T
I
D
P
N
E
A
R
V
Y
-
V
P
D
E
R
F
D
W
L
C
------
Q
L
Y
K
P
K
----
S
E
V
S
A
Y
L
E
I
N
D
I
A
G
L
V
R
-------
L
G
N
A
F
L
S
H
I
R
-
A
V
D
G
I
F
H
V
L
R
A
F
E
D
------------
S
V
D
P
V
R
D
L
E
T
I
G
E
E
L
R
L
K
D
I
E
F
V
Q
N
K
I
D
D
L
E
K
S
----
M
K
R
S
N
----
D
------
K
Q
L
K
L
E
H
E
L
-
C
E
K
V
K
A
H
-
L
E
D
G
-
K
D
V
-
R
F
G
D
W
K
S
A
D
I
E
I
L
N
T
F
Q
L
L
T
A
K
P
-
V
V
Y
L
V
N
M
S
E
-
K
D
Y
Q
R
K
K
N
--
K
F
L
P
K
I
H
A
W
V
Q
E
H
--
G
G
E
---
T
I
I
P
F
S
C
A
F
E
R
L
L
A
D
M
P
P
D
E
A
A
K
Y
C
-
A
E
-
N
Q
I
A
S
V
I
P
K
---------
I
I
K
T
G
F
A
A
I
H
L
I
Y
F
F
T
A
G
P
D
E
----
V
K
C
W
Q
I
-
R
R
Q
T
K
A
P
Q
A
A
G
T
I
H
T
D
F
E
R
G
F
I
C
A
E
V
M
K
F
D
D
L
K
E
L
G
S
E
S
A
V
K
A
A
G
K
Y
R
Q
E
G
K
T
Y
V
V
Q
D
G
D
I
I
F
F
K
F
N
-
22
PsiBlast_CBE
77.84
42%
-69
- C5 -
-
5EE3
1
OLA1_ORYSJ
B:
[26-388]
---------
L
K
I
G
I
V
G
L
P
N
V
G
K
S
T
F
F
N
I
V
T
K
L
S
-
I
-
P
A
E
N
F
P
F
C
T
I
D
P
N
E
A
R
V
Y
-
V
P
D
E
R
F
D
W
L
C
------
Q
L
Y
K
P
K
----
S
E
V
S
A
Y
L
E
I
N
D
I
A
G
L
V
R
----
G
E
G
L
G
N
A
F
L
S
H
I
R
-
A
V
D
G
I
F
H
V
L
R
A
F
E
D
K
----------
D
S
V
D
P
V
R
D
L
E
T
I
G
E
E
L
R
L
K
D
I
E
F
V
Q
N
K
I
D
D
L
E
K
S
----
M
K
R
S
N
----
D
------
K
Q
L
K
L
E
H
E
L
-
C
E
K
V
K
A
H
-
L
E
D
G
-
K
D
V
-
R
F
G
D
W
K
S
A
D
I
E
I
L
N
T
F
Q
L
L
T
A
K
P
-
V
V
Y
L
V
N
M
S
E
-
K
D
Y
Q
R
K
K
N
--
K
F
L
P
K
I
H
A
W
V
Q
E
H
--
G
G
E
---
T
I
I
P
F
S
C
A
F
E
R
L
L
A
D
M
P
P
D
E
A
A
K
Y
C
-
A
E
-
N
Q
I
A
S
V
I
P
K
---------
I
I
K
T
G
F
A
A
I
H
L
I
Y
F
F
T
A
G
P
D
E
----
V
K
C
W
Q
I
-
R
R
Q
T
K
A
P
Q
A
A
G
T
I
H
T
D
F
E
R
G
F
I
C
A
E
V
M
K
F
D
D
L
K
E
L
G
S
E
S
A
V
K
A
A
G
K
Y
R
Q
E
G
K
T
Y
V
V
Q
D
G
D
I
I
F
F
K
F
N
-
5
PsiBlast_PDB
77.58
42%
-67
- C5 -
-
5EE3
2
OLA1_ORYSJ
A:
[26-388]
---------
L
K
I
G
I
V
G
L
P
N
V
G
K
S
T
F
F
N
I
V
T
K
L
S
-
I
-
P
A
E
N
F
P
F
C
T
I
D
P
N
E
A
R
V
Y
-
V
P
D
E
R
F
D
W
L
C
------
Q
L
Y
K
P
K
----
S
E
V
S
A
Y
L
E
I
N
D
I
A
-----------
L
G
N
A
F
L
S
H
I
R
-
A
V
D
G
I
F
H
V
L
R
A
F
E
D
K
----------
D
S
V
D
P
V
R
D
L
E
T
I
G
E
E
L
R
L
K
D
I
E
F
V
Q
N
K
I
D
D
L
E
K
S
----
M
K
R
S
N
----
D
------
K
Q
L
K
L
E
H
E
L
-
C
E
K
V
K
A
H
-
L
E
D
G
-
K
D
V
-
R
F
G
D
W
K
S
A
D
I
E
I
L
N
T
F
Q
L
L
T
A
K
P
-
V
V
Y
L
V
N
M
S
E
-
K
D
Y
Q
R
K
K
N
--
K
F
L
P
K
I
H
A
W
V
Q
E
H
--
G
G
E
---
T
I
I
P
F
S
C
A
F
E
R
L
L
A
D
M
P
P
D
E
A
A
K
Y
C
-
A
E
-
N
Q
I
A
S
V
I
P
K
---------
I
I
K
T
G
F
A
A
I
H
L
I
Y
F
F
T
A
G
P
D
E
----
V
K
C
W
Q
I
-
R
R
Q
T
K
A
P
Q
A
A
G
T
I
H
T
D
F
E
R
G
F
I
C
A
E
V
M
K
F
D
D
L
K
E
L
G
S
E
S
A
V
K
A
A
G
K
Y
R
Q
E
G
K
T
Y
V
V
Q
D
G
D
I
I
F
F
K
F
N
-
6
PsiBlast_PDB
76.96
42%
-64
- C5 -
-
5EE9
1
OLA1_ORYSJ
A:
[26-388]
---------
L
K
I
G
I
V
G
L
P
N
V
G
K
S
T
F
F
N
I
V
T
K
L
S
-
I
-
P
A
E
N
F
P
F
C
T
I
D
P
N
E
A
R
V
Y
-
V
P
D
E
R
F
D
W
L
C
------
Q
L
Y
K
P
K
----
S
E
V
S
A
Y
L
E
I
N
D
I
A
G
L
V
R
---------
N
A
F
L
S
H
I
R
-
A
V
D
G
I
F
H
V
L
R
A
F
E
D
------------
S
V
D
P
V
R
D
L
E
T
I
G
E
E
L
R
L
K
D
I
E
F
V
Q
N
K
I
D
D
L
E
K
S
----
M
K
R
S
N
----
D
------
K
Q
L
K
L
E
H
E
L
-
C
E
K
V
K
A
H
-
L
E
D
G
-
K
D
V
-
R
F
G
D
W
K
S
A
D
I
E
I
L
N
T
F
Q
L
L
T
A
K
P
-
V
V
Y
L
V
N
M
S
E
-
K
D
Y
Q
R
K
K
N
--
K
F
L
P
K
I
H
A
W
V
Q
E
H
--
G
G
E
---
T
I
I
P
F
S
C
A
F
E
R
L
L
A
D
M
P
P
D
E
A
A
K
Y
C
-
A
E
-
N
Q
I
A
S
V
I
P
K
---------
I
I
K
T
G
F
A
A
I
H
L
I
Y
F
F
T
A
G
P
D
E
----
V
K
C
W
Q
I
-
R
R
Q
T
K
A
P
Q
A
A
G
T
I
H
T
D
F
E
R
G
F
I
C
A
E
V
M
K
F
D
D
L
K
E
L
G
S
E
S
A
V
K
A
A
G
K
Y
R
Q
E
G
K
T
Y
V
V
Q
D
G
D
I
I
F
F
K
F
N
-
3
PsiBlast_PDB
75.70
52%
29
- C5 -
-
2DBY
4
?
A:
[2-366]
---------
L
A
V
G
I
V
G
L
P
N
V
G
K
S
T
L
F
N
A
L
T
R
A
N
-
A
-
L
A
A
N
Y
P
F
A
T
I
D
K
N
V
G
V
V
P
-
L
E
D
E
R
L
Y
A
L
Q
R
T
F
AKG
E
R
V
P
P
------
V
V
P
T
H
V
E
F
V
D
I
A
G
L
V
K
G
A
H
K
G
E
G
L
G
N
Q
F
L
A
H
I
R
-
E
V
A
A
I
A
H
V
L
R
C
F
P
D
P
---------------
L
E
D
A
E
V
V
E
T
E
L
L
L
A
D
L
A
T
L
E
R
R
L
E
R
L
R
K
E
----
A
R
A
------
D
------
R
E
R
L
P
L
L
E
A
-
A
E
G
L
Y
V
H
-
L
Q
E
G
-
K
P
A
-
R
T
F
P
P
S
E
A
V
A
R
F
L
K
E
T
P
L
L
T
A
K
P
-
V
I
Y
V
A
N
V
A
E
-
E
D
L
P
D
G
R
G
-
N
P
Q
V
E
A
V
R
R
K
A
L
E
E
--
G
A
E
---
V
V
V
-
V
S
A
R
L
E
A
E
L
A
E
L
S
G
E
E
A
R
E
L
L
A
A
Y
-
G
L
Q
E
S
G
L
Q
R
---------
L
A
R
A
G
Y
R
A
L
D
L
L
T
F
F
T
A
G
E
K
E
----
V
R
A
W
T
V
-
R
R
G
T
K
A
P
R
A
A
G
E
I
H
S
D
M
E
R
G
F
I
R
A
E
V
I
P
W
D
K
L
V
E
A
G
G
W
A
R
A
K
E
R
G
W
V
R
L
E
G
K
D
Y
E
V
Q
D
G
D
V
I
Y
V
L
F
--
2
PsiBlast_PDB
73.24
52%
40
- C5 -
-
2DWQ
-
?
A:
[2-367]
---------
L
A
V
G
I
V
G
L
P
N
V
G
K
S
T
L
F
N
A
L
T
R
A
N
-
A
-
L
A
A
-----
T
I
D
K
N
V
G
V
V
P
-
L
E
D
E
R
L
Y
A
L
Q
R
T
F
AKG
E
R
V
P
P
------
V
V
P
T
H
V
E
F
V
D
I
A
G
L
V
K
G
A
H
K
G
E
G
L
G
N
Q
F
L
A
H
I
R
-
E
V
A
A
I
A
H
V
L
R
C
F
P
D
P
-------------
D
P
L
E
D
A
E
V
V
E
T
E
L
L
L
A
D
L
A
T
L
E
R
R
L
E
R
L
R
K
E
----
A
R
A
------
D
------
R
E
R
L
P
L
L
E
A
-
A
E
G
L
Y
V
H
-
L
Q
E
G
-
K
P
A
-
R
T
F
P
P
S
E
A
V
A
R
F
L
K
E
T
P
L
L
T
A
K
P
-
V
I
Y
V
A
N
V
A
E
-
E
D
L
P
D
G
R
G
-
N
P
Q
V
E
A
V
R
R
K
A
L
E
E
--
G
A
E
---
V
V
V
-
V
S
A
R
L
E
A
E
L
A
E
L
S
G
E
E
A
R
E
L
L
A
A
Y
-
G
L
Q
E
S
G
L
Q
R
---------
L
A
R
A
G
Y
R
A
L
D
L
L
T
F
F
T
A
G
E
K
E
----
V
R
A
W
T
V
-
R
R
G
T
K
A
P
R
A
A
G
E
I
H
S
D
M
E
R
G
F
I
R
A
E
V
I
P
W
D
K
L
V
E
A
G
G
W
A
R
A
K
E
R
G
W
V
R
L
E
G
K
D
Y
E
V
Q
D
G
D
V
I
Y
V
L
F
N
-
100
Fugue
71.02
42%
-
- C5 -
-
5EE0
-
OLA1_ORYSJ
A:
[16-387]
PILGRFS
S
H
L
K
I
G
I
V
G
L
P
N
V
G
K
S
T
F
F
N
I
V
T
K
L
S
-
I
-
P
A
E
N
F
P
F
C
T
I
D
P
N
E
A
R
V
Y
-
V
P
D
E
R
F
D
W
L
C
------
Q
L
Y
K
P
K
----
S
E
V
S
A
Y
L
E
I
N
D
I
A
G
L
--------
G
L
G
N
A
F
L
S
H
I
R
-
A
V
D
G
I
F
H
V
L
R
A
F
E
D
----
K
E
V
T
H
I
D
D
S
V
D
P
V
R
D
L
E
T
I
G
E
E
L
R
L
K
D
I
E
F
V
Q
N
K
I
D
D
L
E
K
S
----
M
K
R
S
N
----
D
------
K
Q
L
K
L
E
H
E
L
-
C
E
K
V
K
A
H
-
L
E
D
G
-
K
D
V
-
R
F
G
D
W
K
S
A
D
I
E
I
L
N
T
F
Q
L
L
T
A
K
P
-
V
V
Y
L
V
N
M
S
E
-
K
D
Y
Q
R
K
K
N
--
K
F
L
P
K
I
H
A
W
V
Q
E
H
--
G
G
E
T
--
I
I
P
-
F
S
C
A
F
E
R
L
L
A
D
M
P
P
D
E
A
A
K
Y
C
A
E
N
-
Q
I
-
A
S
V
I
P
K
---------
I
I
K
T
G
F
A
A
I
H
L
I
Y
F
F
T
A
G
P
D
E
----
V
K
C
W
Q
I
-
R
R
Q
T
K
A
P
Q
A
A
G
T
I
H
T
D
F
E
R
G
F
I
C
A
E
V
M
K
F
D
D
L
K
E
L
G
S
E
S
A
V
K
A
A
G
K
Y
R
Q
E
G
K
T
Y
V
V
Q
D
G
D
I
I
F
F
K
F
N
-
77
HHSearch
67.85
40%
30
- C5 -
-
1NI3
-
OLA1_SCHPO
A:
[20-388]
--------
N
L
K
T
G
I
V
G
M
P
N
V
G
K
S
T
F
F
R
A
I
T
K
S
V
-
L
G
N
P
A
N
Y
P
Y
A
T
I
D
P
E
E
A
K
V
A
-
V
P
D
E
R
F
D
W
L
C
------
E
A
Y
K
P
K
----
S
R
V
P
A
F
L
T
V
F
D
I
A
G
L
T
K
G
A
S
T
G
V
G
L
G
N
A
F
L
S
H
V
R
-
A
V
D
A
I
Y
Q
V
V
R
A
F
D
D
A
E
I
I
H
V
E
G
D
----
V
D
P
I
R
D
L
S
I
I
V
D
E
L
L
I
K
D
A
E
F
V
E
K
H
L
E
G
L
R
K
I
----
T
S
R
G
A
NTLE
M
------
K
A
K
K
E
E
Q
A
I
-
I
E
K
V
Y
Q
Y
-
L
T
E
T
K
Q
P
I
-
R
K
G
D
W
S
N
R
E
V
E
I
I
N
S
L
Y
L
L
T
A
K
P
-
V
I
Y
L
V
N
M
S
E
-
R
D
F
L
R
-
Q
K
-
N
K
Y
L
P
K
I
K
K
W
I
D
E
N
SP
G
D
T
---
L
I
P
-
M
S
V
A
F
E
E
R
L
T
N
F
T
E
E
E
A
I
E
E
C
K
K
L
-
N
T
K
-
S
M
L
P
K
---------
I
I
V
T
G
Y
N
A
L
N
L
I
N
Y
F
T
C
G
E
D
E
----
V
R
S
W
T
I
-
R
K
G
T
K
A
P
Q
A
A
G
V
I
H
T
D
F
E
K
A
F
V
V
G
E
I
M
H
Y
Q
D
L
F
D
Y
K
T
E
N
A
C
R
A
A
G
K
Y
L
T
K
G
K
E
Y
V
M
E
S
G
D
I
A
H
W
K
---
7
PsiBlast_PDB
66.99
40%
37
- C5 -
-
1NI3
-
OLA1_SCHPO
A:
[21-388]
---------
L
K
T
G
I
V
G
M
P
N
V
G
K
S
T
F
F
R
A
I
T
K
S
V
L
G
-
N
P
A
N
Y
P
Y
A
T
I
D
P
E
E
A
K
V
A
-
V
P
D
E
R
F
D
W
L
C
------
E
A
Y
K
P
K
----
S
R
V
P
A
F
L
T
V
F
D
I
A
G
L
T
K
G
A
S
T
G
V
G
L
G
N
A
F
L
S
H
V
R
-
A
V
D
A
I
Y
Q
V
V
R
A
F
D
D
A
E
I
I
H
V
E
G
D
----
V
D
P
I
R
D
L
S
I
I
V
D
E
L
L
I
K
D
A
E
F
V
E
K
H
L
E
G
L
R
K
I
TSRG
A
N
T
L
E
----
M
------
K
A
K
K
E
E
Q
A
I
-
I
E
K
V
Y
Q
Y
-
L
T
E
T
-
K
Q
P
I
R
K
G
D
W
S
N
R
E
V
E
I
I
N
S
L
Y
L
L
T
A
K
P
-
V
I
Y
L
V
N
M
S
E
R
D
F
L
R
Q
K
N
K
---
Y
L
P
K
I
K
K
W
I
-
D
E
--
N
S
P
G
D
T
L
I
P
-
M
S
V
A
F
E
E
R
L
T
N
F
T
E
E
E
A
I
E
E
C
K
K
L
-
N
-
T
K
S
M
L
P
K
---------
I
I
V
T
G
Y
N
A
L
N
L
I
N
Y
F
T
C
G
E
D
E
----
V
R
S
W
T
I
-
R
K
G
T
K
A
P
Q
A
A
G
V
I
H
T
D
F
E
K
A
F
V
V
G
E
I
M
H
Y
Q
D
L
F
D
Y
K
T
E
N
A
C
R
A
A
G
K
Y
L
T
K
G
K
E
Y
V
M
E
S
G
D
I
A
H
W
K
---
87
HHSearch
44.64
42%
-139
- C5 -
-
1LNZ
1
OBG_BACSU
B:
[159-248]
---------
A
D
V
G
L
V
G
F
P
S
V
G
K
S
T
L
L
S
V
V
S
S
A
K
-
P
-
K
I
---------
P
N
L
G
M
V
E
-
T
D
D
G
--------------------------
R
S
F
V
M
A
D
L
P
G
L
I
E
G
--------
H
Q
F
L
R
H
I
E
-
R
T
R
V
I
V
H
V
I
D
M
S
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
86
HHSearch
42.13
46%
-103
- C5 -
-
1UDX
1
OBG_THET8
A:
[157-251]
--------
I
A
D
V
G
L
V
G
Y
P
N
A
G
K
S
S
L
L
A
A
M
T
R
A
H
-
P
-
K
I
A
P
Y
P
F
T
T
L
S
P
N
L
G
V
V
E
-
V
S
E
E
--------------------------
E
R
F
T
L
A
D
I
P
G
I
I
E
G
A
S
E
G
K
G
L
G
L
E
F
L
R
H
I
A
-
R
T
R
V
L
L
Y
V
L
D
A
A
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
101
Fugue
41.44
22%
35
- C5 -
-
1WXQ
-
?
A:
[2-395]
----------
E
I
G
V
V
G
K
P
N
V
G
K
S
T
F
F
S
A
A
T
L
----------------
A
N
V
G
V
T
Y
A
I
T
D
H
P
C
K
E
L
G
------
C
S
P
N
P
---------
Q
N
Y
E
Y
R
N
G
L
A
L
I
P
V
K
M
----
V
D
V
A
F
L
D
D
L
R
M
A
S
A
L
I
H
V
V
D
A
T
G
K
T
D
P
E
G
Q
P
T
D
Y
H
D
----
P
V
E
D
I
E
F
L
E
R
E
I
D
Y
W
I
Y
G
I
L
S
K
G
W
D
K
F
A
K
R
----
I
K
L
Q
K
----
I
K
L
E
S
A
I
A
E
H
L
S
G
I
G
V
N
E
N
D
V
W
E
A
M
H
K
L
N
-
L
P
E
-
D
P
T
K
W
S
Q
D
D
L
L
A
F
A
S
E
I
R
R
V
N
K
P
M
V
I
A
A
N
K
A
D
A
-
A
------
S
-
D
E
Q
I
K
R
L
V
R
E
E
E
K
R
--
G
Y
I
---
V
I
P
-
T
S
A
A
A
E
L
T
L
R
K
A
A
K
A
G
F
I
E
Y
I
P
A
L
M
V
I
K
E
K
V
L
D
R
FGSTG
V
Q
E
V
I
N
R
V
V
F
D
L
L
K
L
I
P
V
Y
P
V
H
D
E
Q
FGNV
L
P
H
V
F
L
M
K
K
G
S
T
P
R
D
L
A
F
K
V
H
T
D
L
G
K
G
F
L
Y
A
I
N
-----------------
A
R
T
K
R
R
V
G
E
D
Y
E
L
Q
F
N
D
I
V
K
I
V
S
V
-
88
HHSearch
40.55
42%
-120
- C5 -
-
1LNZ
-
OBG_BACSU
A:
[159-248]
---------
A
D
V
G
L
V
G
F
P
S
V
G
K
S
T
L
L
S
V
V
S
S
A
K
-
P
-
K
I
A
D
Y
H
F
T
T
L
V
P
N
L
G
M
V
E
-
T
D
D
G
--------------------------
R
S
F
V
M
A
D
L
P
G
L
I
E
G
A
H
Q
G
V
G
L
G
H
Q
F
L
R
H
I
E
-
R
T
R
V
I
V
H
V
I
D
M
S
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
40.51
37%
-97
- C5 -
-
1LNZ
-
OBG_BACSU
A:
[162-265]
------------
G
L
V
G
F
P
S
V
G
K
S
T
L
L
S
V
V
S
S
A
K
-
P
-
K
I
A
D
Y
H
F
T
T
L
V
P
N
L
G
M
V
E
-
T
D
D
G
R
--------------------------
S
F
V
M
A
D
L
P
G
L
I
E
G
A
H
Q
G
V
G
L
G
H
Q
F
L
R
H
I
E
-
R
T
R
V
I
V
H
V
I
----
D
M
S
G
L
--
E
G
R
-----
D
P
Y
D
D
Y
L
T
I
N
Q
E
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
103
Fugue
37.88
15%
-105
- C5 -
-
1M2O
1
SAR1_YEAST
B:
[24-190]
---------
G
K
L
L
F
L
G
L
D
N
A
G
K
T
T
L
L
H
M
L
K
N
-----
D
R
L
A
T
L
Q
P
T
W
H
P
T
S
E
E
L
A
-
I
G
N
---------------------------
I
K
F
T
T
F
D
L
G
G
-------
H
I
Q
A
R
R
L
W
K
D
Y
F
P
-
E
V
N
G
I
V
F
L
V
D
A
-
A
D
P
E
R
F
D
E
A
R
V
E
L
D
A
L
F
N
I
A
E
L
K
D
V
P
F
-
V
I
L
G
N
K
I
D
A
---------------
P
N
A
V
----
S
------
E
A
E
L
R
S
A
L
G
-
L
L
N
T
T
G
I
-
E
G
Q
R
-
P
V
E
-
V
F
M
C
S
V
V
M
R
N
G
Y
L
E
A
F
Q
W
L
S
Q
Y
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
37.51
46%
-127
- C5 -
-
3W5I
-
?
A:
[8-44]
-------------
L
L
G
M
P
N
T
G
K
S
T
L
F
N
R
M
T
G
G
A
-
A
-
R
V
G
N
W
P
G
I
T
V
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------