@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : spr0045: (2017-12-14 )
MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAGKGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSKRFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIADDQQIAYLKEEARRINELLKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLGELTDVYEIVWEKLQELK
Atome Classification :
(35 SA)
...-..-....10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180-....---.....190.......200.-.-.-.-.-..210.......220.......230....
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MSK-
Q
L
-
I
YSGKAK
D
I
Y
TTEDE
N
L
I
I
S
T
YKDQATAFNGV
K
K
E
QIAGKGV
L
N
N
Q
I
S
S
F
I
F
E
K
L
N
A
A
G
V
A
T
H
F
V
E
K
LS
D
T
E
Q
LNKK
V
K
I
I
P
L
E
V
V
L
R
NYTAGS
F
S
KRFGVDEGIALET
P
I
V
E
F
Y
YKNDDLDDPFINDE
H
V
K
F
L
Q
IADD
Q
Q
I
A
Y
L
K
E
E
A
R
R
I
N
E
L
L
K
V
W
F
A
E
IG
L
K
L
I
D
F
K
L
E
FG---FDKD---
G
K
I
I
L
A
DEFSPDN
C
R
L
WDA-D-G-N-H-M
D
K
D
V
F
R
R
G
L
G
E
L
T
D
V
Y
E
I
V
W
E
K
L
-
Q
ELK
47
HHSearch
91.60
99%
-64
- C2 -
-
4FE2
7
PUR7_STRPN
A:
[23-255]
--
K
-
Q
L
-
I
Y
S
G
K
A
K
D
I
Y
T
T
E
D
E
N
L
I
I
S
T
Y
K
D
Q
A
T
A
F
N
G
V
K
K
E
Q
I
A
G
K
G
V
L
N
N
Q
I
S
S
F
I
F
E
K
L
N
V
A
G
V
A
T
H
F
V
E
K
L
S
D
T
E
Q
L
N
K
K
V
K
I
I
P
L
E
V
V
L
R
N
Y
T
A
G
S
F
S
K
R
F
G
V
D
E
G
I
A
L
E
T
P
I
V
E
F
Y
Y
K
N
D
D
L
D
D
P
F
I
N
D
E
H
V
K
F
L
Q
I
A
G
D
Q
Q
I
A
Y
L
K
E
E
T
R
R
I
N
E
L
L
K
V
W
F
A
E
I
G
L
K
L
I
D
F
K
L
E
F
G
---
F
D
K
D
---
G
K
I
I
L
A
D
E
F
S
P
D
N
C
R
L
W
D
A
-
D
-
G
-
N
-
H
-
M
D
K
D
V
F
R
R
G
L
G
E
L
T
D
V
Y
E
I
V
W
E
K
L
-
Q
E
L
K
1
PsiBlast_PDB
91.35
98%
-64
- C2 -
-
4FE2
7
PUR7_STRPN
A:
[23-255]
--
K
-
Q
L
-
I
Y
S
G
K
A
K
D
I
Y
T
T
E
D
E
N
L
I
I
S
T
Y
K
D
Q
A
T
A
F
N
G
V
K
K
E
Q
I
A
G
K
G
V
L
N
N
Q
I
S
S
F
I
F
E
K
L
N
V
A
G
V
A
T
H
F
V
E
K
L
S
D
T
E
Q
L
N
K
K
V
K
I
I
P
L
E
V
V
L
R
N
Y
T
A
G
S
F
S
K
R
F
G
V
D
E
G
I
A
L
E
T
P
I
V
E
F
Y
Y
K
N
D
D
L
D
D
P
F
I
N
D
E
H
V
K
F
L
Q
I
A
G
D
Q
Q
I
A
Y
L
K
E
E
T
R
R
I
N
E
L
L
K
V
W
F
A
E
I
G
L
K
L
I
D
F
K
L
E
F
G
---
F
D
K
D
---
G
K
I
I
L
A
D
E
F
S
P
D
N
C
R
L
W
D
A
-
D
-
G
-
N
-
H
-
M
D
K
D
V
F
R
R
G
L
G
E
L
T
D
V
Y
E
I
V
W
E
K
L
-
Q
E
L
K
48
HHSearch
91.30
99%
-61
- C2 -
-
4FGR
1
PUR7_STRPN
A:
[22-255]
-
S
K
-
Q
L
-
I
Y
S
G
K
A
K
D
I
Y
T
T
E
D
E
N
L
I
I
S
T
Y
K
D
Q
A
T
A
F
N
G
V
K
K
E
Q
I
A
G
K
G
V
L
N
N
Q
I
S
S
F
I
F
E
K
L
N
V
A
G
V
A
T
H
F
V
E
K
L
S
D
T
E
Q
L
N
K
K
V
K
I
I
P
L
E
V
V
L
R
N
Y
T
A
G
S
F
S
K
R
F
G
V
D
E
G
I
A
L
E
T
P
I
V
E
F
Y
Y
K
N
D
D
L
D
D
P
F
I
N
D
E
H
V
K
F
L
Q
I
A
G
D
Q
Q
I
A
Y
L
K
E
E
T
R
R
I
N
E
L
L
K
V
W
F
A
E
I
G
L
K
L
I
D
F
K
L
E
F
G
---
F
D
K
D
---
G
K
I
I
L
A
D
E
F
S
P
D
N
C
R
L
W
D
A
-
D
-
G
-
N
-
H
-
M
D
K
D
V
F
R
R
G
L
G
E
L
T
D
V
Y
E
I
V
W
E
K
L
-
Q
E
L
K
2
PsiBlast_PDB
91.17
98%
-63
- C2 -
-
4FGR
1
PUR7_STRPN
A:
[21-255]
M
S
K
-
Q
L
-
I
Y
S
G
K
A
K
D
I
Y
T
T
E
D
E
N
L
I
I
S
T
Y
K
D
Q
A
T
A
F
N
G
V
K
K
E
Q
I
A
G
K
G
V
L
N
N
Q
I
S
S
F
I
F
E
K
L
N
V
A
G
V
A
T
H
F
V
E
K
L
S
D
T
E
Q
L
N
K
K
V
K
I
I
P
L
E
V
V
L
R
N
Y
T
A
G
S
F
S
K
R
F
G
V
D
E
G
I
A
L
E
T
P
I
V
E
F
Y
Y
K
N
D
D
L
D
D
P
F
I
N
D
E
H
V
K
F
L
Q
I
A
G
D
Q
Q
I
A
Y
L
K
E
E
T
R
R
I
N
E
L
L
K
V
W
F
A
E
I
G
L
K
L
I
D
F
K
L
E
F
G
---
F
D
K
D
---
G
K
I
I
L
A
D
E
F
S
P
D
N
C
R
L
W
D
A
-
D
-
G
-
N
-
H
-
M
D
K
D
V
F
R
R
G
L
G
E
L
T
D
V
Y
E
I
V
W
E
K
L
-
Q
E
L
K
3
PsiBlast_PDB
90.95
98%
-64
- C2 -
-
4NYE
1
PUR7_STRPN
A:
[21-255]
M
S
K
-
Q
L
-
I
Y
S
G
K
A
K
D
I
Y
T
T
E
D
E
N
L
I
I
S
T
Y
K
D
Q
A
T
A
F
N
G
V
K
K
E
Q
I
A
G
K
G
V
L
N
N
Q
I
S
S
F
I
F
E
K
L
N
V
A
G
V
A
T
H
F
V
E
K
L
S
D
T
E
Q
L
N
K
K
V
K
I
I
P
L
E
V
V
L
R
N
Y
T
A
G
S
F
S
K
R
F
G
V
D
E
G
I
A
L
E
T
P
I
V
E
F
Y
Y
K
N
D
D
L
D
D
P
F
I
N
D
E
H
V
K
F
L
Q
I
A
G
D
Q
Q
I
A
Y
L
K
E
E
T
R
R
I
N
E
L
L
K
V
W
F
A
E
I
G
L
K
L
I
D
F
K
L
E
F
G
---
F
D
K
D
---
G
K
I
I
L
A
D
E
F
S
P
D
N
C
R
L
W
D
A
-
D
-
G
-
N
-
H
-
M
D
K
D
V
F
R
R
G
L
G
E
L
T
D
V
Y
E
I
V
W
E
K
L
-
Q
E
L
K
23
PsiBlast_CBE
89.68
98%
-63
- C2 -
-
4FE2
3
PUR7_STRPN
B:
[21-255]
M
S
K
-
Q
L
-
I
Y
S
G
K
A
K
D
I
Y
T
T
E
D
E
N
L
I
I
S
T
Y
K
D
Q
A
T
A
F
N
G
V
K
K
E
Q
I
A
G
K
G
V
L
N
N
Q
I
S
S
F
I
F
E
K
L
N
V
A
G
V
A
T
H
F
V
E
K
L
S
D
T
E
Q
L
N
K
K
V
K
I
I
P
L
E
V
V
L
R
N
Y
T
A
G
S
F
S
K
R
F
G
V
D
E
G
I
A
L
E
T
P
I
V
E
F
Y
Y
K
N
D
D
L
D
D
P
F
I
N
D
E
H
V
K
F
L
Q
I
A
G
D
Q
Q
I
A
Y
L
K
E
E
T
R
R
I
N
E
L
L
K
V
W
F
A
E
I
G
L
K
L
I
D
F
K
L
E
F
G
---
F
D
K
D
---
G
K
I
I
L
A
D
E
F
S
P
D
N
C
R
L
W
D
A
-
D
-
G
-
N
-
H
-
M
D
K
D
V
F
R
R
G
L
G
E
L
T
D
V
Y
E
I
V
W
E
K
L
-
Q
E
L
K
22
PsiBlast_CBE
89.56
98%
-66
- C2 -
-
4FGR
1
PUR7_STRPN
B:
[22-254]
-
S
K
-
Q
L
-
I
Y
S
G
K
A
K
D
I
Y
T
T
E
D
E
N
L
I
I
S
T
Y
K
D
Q
A
T
A
F
N
G
V
K
K
E
Q
I
A
G
K
G
V
L
N
N
Q
I
S
S
F
I
F
E
K
L
N
V
A
G
V
A
T
H
F
V
E
K
L
S
D
T
E
Q
L
N
K
K
V
K
I
I
P
L
E
V
V
L
R
N
Y
T
A
G
S
F
S
K
R
F
G
V
D
E
G
I
A
L
E
T
P
I
V
E
F
Y
Y
K
N
D
D
L
D
D
P
F
I
N
D
E
H
V
K
F
L
Q
I
A
G
D
Q
Q
I
A
Y
L
K
E
E
T
R
R
I
N
E
L
L
K
V
W
F
A
E
I
G
L
K
L
I
D
F
K
L
E
F
G
---
F
D
K
D
---
G
K
I
I
L
A
D
E
F
S
P
D
N
C
R
L
W
D
A
-
D
-
G
-
N
-
H
-
M
D
K
D
V
F
R
R
G
L
G
E
L
T
D
V
Y
E
I
V
W
E
K
L
-
Q
E
L
-
21
PsiBlast_CBE
89.25
98%
-65
- C2 -
-
4NYE
1
PUR7_STRPN
B:
[22-254]
-
S
K
-
Q
L
-
I
Y
S
G
K
A
K
D
I
Y
T
T
E
D
E
N
L
I
I
S
T
Y
K
D
Q
A
T
A
F
N
G
V
K
K
E
Q
I
A
G
K
G
V
L
N
N
Q
I
S
S
F
I
F
E
K
L
N
V
A
G
V
A
T
H
F
V
E
K
L
S
D
T
E
Q
L
N
K
K
V
K
I
I
P
L
E
V
V
L
R
N
Y
T
A
G
S
F
S
K
R
F
G
V
D
E
G
I
A
L
E
T
P
I
V
E
F
Y
Y
K
N
D
D
L
D
D
P
F
I
N
D
E
H
V
K
F
L
Q
I
A
G
D
Q
Q
I
A
Y
L
K
E
E
T
R
R
I
N
E
L
L
K
V
W
F
A
E
I
G
L
K
L
I
D
F
K
L
E
F
G
---
F
D
K
D
---
G
K
I
I
L
A
D
E
F
S
P
D
N
C
R
L
W
D
A
-
D
-
G
-
N
-
H
-
M
D
K
D
V
F
R
R
G
L
G
E
L
T
D
V
Y
E
I
V
W
E
K
L
-
Q
E
L
-
24
PsiBlast_CBE
80.88
58%
-52
- C2 -
-
2YWV
1
?
B:
[7-236]
--
Q
-
Q
L
-
L
Y
E
G
K
A
K
K
I
Y
A
T
D
E
P
D
V
L
W
V
E
Y
K
D
S
A
T
A
F
N
G
E
K
K
A
T
I
A
G
K
G
R
L
N
N
E
I
S
S
L
L
F
L
K
L
R
E
A
G
I
A
N
H
F
I
E
K
L
S
P
T
E
Q
L
V
R
R
V
T
I
I
P
L
E
V
V
V
R
N
V
V
A
G
S
L
A
K
R
I
G
L
E
E
G
T
P
L
E
A
P
L
V
E
F
Y
Y
K
N
D
D
L
G
D
P
L
L
L
E
D
H
I
F
I
L
K
L
A
S
R
E
E
V
A
A
L
K
Q
A
A
L
A
V
N
D
V
L
R
L
H
F
A
E
R
N
V
R
L
I
D
F
K
L
E
F
G
---
R
T
A
D
---
G
A
I
L
L
A
D
E
I
S
P
D
T
C
R
L
W
D
A
-
K
-
T
-
N
-
E
K
L
D
K
D
V
F
R
R
D
L
G
S
L
T
D
A
Y
E
V
I
L
Q
R
L
-----
51
HHSearch
80.55
57%
-46
- C2 -
-
2YWV
1
?
B:
[6-239]
-
K
Q
-
Q
L
-
L
Y
E
G
K
A
K
K
I
Y
A
T
D
E
P
D
V
L
W
V
E
Y
K
D
S
A
T
A
F
N
G
E
K
K
A
T
I
A
G
K
G
R
L
N
N
E
I
S
S
L
L
F
L
K
L
R
E
A
G
I
A
N
H
F
I
E
K
L
S
P
T
E
Q
L
V
R
R
V
T
I
I
P
L
E
V
V
V
R
N
V
V
A
G
S
L
A
K
R
I
G
L
E
E
G
T
P
L
E
A
P
L
V
E
F
Y
Y
K
N
D
D
L
G
D
P
L
L
L
E
D
H
I
F
I
L
K
L
A
S
R
E
E
V
A
A
L
K
Q
A
A
L
A
V
N
D
V
L
R
L
H
F
A
E
R
N
V
R
L
I
D
F
K
L
E
F
G
---
R
T
A
D
---
G
A
I
L
L
A
D
E
I
S
P
D
T
C
R
L
W
D
A
K
T
-
N
-
E
-
K
-
L
D
K
D
V
F
R
R
D
L
G
S
L
T
D
A
Y
E
V
I
L
Q
R
L
-
G
G
E
-
4
PsiBlast_PDB
80.22
58%
-53
- C2 -
-
2YWV
1
?
A:
[7-236]
--
Q
-
Q
L
-
L
Y
E
G
K
A
K
K
I
Y
A
T
D
E
P
D
V
L
W
V
E
Y
K
D
S
A
T
A
F
N
G
E
K
K
A
T
I
A
G
K
G
R
L
N
N
E
I
S
S
L
L
F
L
K
L
R
E
A
G
I
A
N
H
F
I
E
K
L
S
P
T
E
Q
L
V
R
R
V
T
I
I
P
L
E
V
V
V
R
N
V
V
A
G
S
L
A
K
R
I
G
L
E
E
G
T
P
L
E
A
P
L
V
E
F
Y
Y
K
N
D
D
L
G
D
P
L
L
L
E
D
H
I
F
I
L
K
L
A
S
R
E
E
V
A
A
L
K
Q
A
A
L
A
V
N
D
V
L
R
L
H
F
A
E
R
N
V
R
L
I
D
F
K
L
E
F
G
---
R
T
A
D
---
G
A
I
L
L
A
D
E
I
S
P
D
T
C
R
L
W
D
A
-
K
-
T
-
N
-
E
K
L
D
K
D
V
F
R
R
D
L
G
S
L
T
D
A
Y
E
V
I
L
Q
R
L
-----
11
PsiBlast_PDB
79.19
47%
-82
- C2 -
-
4O7S
1
PUR7_PYRHO
A:
[15-231]
---------------
M
I
P
I
D
D
D
K
L
I
M
E
-
F
K
D
D
A
T
A
F
D
G
T
K
K
A
R
F
K
G
K
G
W
L
N
A
Q
L
S
V
I
F
F
K
L
L
E
E
H
G
I
K
T
H
F
I
G
V
A
G
G
N
R
L
I
V
E
K
L
D
M
Y
P
L
E
V
V
V
R
N
V
V
A
G
S
L
K
K
R
L
P
L
P
E
G
Y
E
L
P
E
P
I
V
E
L
Y
Y
K
N
D
E
L
H
D
P
M
I
N
Y
Y
H
A
K
V
L
G
I
S
L
D
-
E
I
K
K
I
E
E
I
A
L
K
V
N
E
I
L
K
D
Y
L
A
K
K
G
I
I
L
V
D
F
K
L
E
F
G
---
K
D
K
N
---
G
D
I
V
L
A
D
E
I
S
P
D
T
C
R
F
W
D
A
-
K
-
T
-
K
-
R
S
L
D
K
D
V
F
R
F
D
K
G
D
L
I
E
A
Y
K
E
I
Y
E
R
I
-----
16
PsiBlast_PDB
77.18
47%
-67
- C2 -
-
4O86
2
PUR7_PYRHO
A:
[12-231]
------------
A
K
K
M
I
P
I
D
D
D
K
L
I
M
E
-
F
K
D
D
A
T
A
F
D
G
T
K
K
A
R
F
K
G
K
G
W
L
N
A
Q
L
S
V
I
F
F
K
L
L
E
E
H
G
I
K
T
H
F
I
G
V
A
G
G
N
R
L
I
V
E
K
L
D
M
Y
P
L
E
V
V
V
R
N
V
V
A
G
S
L
K
K
R
L
P
L
P
E
G
Y
E
L
P
E
P
I
V
E
L
Y
Y
K
N
D
E
L
H
D
P
M
I
N
Y
Y
H
A
K
V
L
G
I
S
L
D
-
E
I
K
K
I
E
E
I
A
L
K
V
N
E
I
L
K
D
Y
L
A
K
K
G
I
I
L
V
D
F
K
L
E
F
G
---
K
D
K
N
---
G
D
I
V
L
A
D
E
I
S
P
D
T
C
R
F
W
D
A
-
K
-
T
-
K
-
R
S
L
D
K
D
V
F
R
F
D
K
G
D
L
I
E
A
Y
K
E
I
Y
E
R
I
-----
14
PsiBlast_PDB
77.01
47%
-63
- C2 -
-
4O7W
2
PUR7_PYRHO
A:
[7-231]
-------
V
Y
E
G
K
A
K
K
M
I
P
I
D
D
D
K
L
I
M
E
-
F
K
D
D
A
T
A
F
D
G
T
K
K
A
R
F
K
G
K
G
W
L
N
A
Q
L
S
V
I
F
F
K
L
L
E
E
H
G
I
K
T
H
F
I
G
V
A
G
G
N
R
L
I
V
E
K
L
D
M
Y
P
L
E
V
V
V
R
N
V
V
A
G
S
L
K
K
R
L
P
L
P
E
G
Y
E
L
P
E
P
I
V
E
L
Y
Y
K
N
D
E
L
H
D
P
M
I
N
Y
Y
H
A
K
V
L
G
I
S
L
D
-
E
I
K
K
I
E
E
I
A
L
K
V
N
E
I
L
K
D
Y
L
A
K
K
G
I
I
L
V
D
F
K
L
E
F
G
---
K
D
K
N
---
G
D
I
V
L
A
D
E
I
S
P
D
T
C
R
F
W
D
A
-
K
-
T
-
K
-
R
S
L
D
K
D
V
F
R
F
D
K
G
D
L
I
E
A
Y
K
E
I
Y
E
R
I
-----
7
PsiBlast_PDB
76.93
47%
-66
- C2 -
-
3U55
-
PUR7_PYRHO
A:
[12-231]
------------
A
K
K
M
I
P
I
D
D
D
K
L
I
M
E
-
F
K
D
D
A
T
A
F
D
G
T
K
K
A
R
F
K
G
K
G
W
L
N
A
Q
L
S
V
I
F
F
K
L
L
E
E
H
G
I
K
T
H
F
I
G
V
A
G
G
N
R
L
I
V
E
K
L
D
M
Y
P
L
E
V
V
V
R
N
V
V
A
G
S
L
K
K
R
L
P
L
P
E
G
Y
E
L
P
E
P
I
V
E
L
Y
Y
K
N
D
E
L
H
D
P
M
I
N
Y
Y
H
A
K
V
L
G
I
S
L
D
-
E
I
K
K
I
E
E
I
A
L
K
V
N
E
I
L
K
D
Y
L
A
K
K
G
I
I
L
V
D
F
K
L
E
F
G
---
K
D
K
N
---
G
D
I
V
L
A
D
E
I
S
P
D
T
C
R
F
W
D
A
-
K
-
T
-
K
-
R
S
L
D
K
D
V
F
R
F
D
K
G
D
L
I
E
A
Y
K
E
I
Y
E
R
I
-----
8
PsiBlast_PDB
76.55
47%
-59
- C2 -
-
4O7L
1
PUR7_PYRHO
A:
[7-231]
-------
V
Y
E
G
K
A
K
K
M
I
P
I
D
D
D
K
L
I
M
E
-
F
K
D
D
A
T
A
F
D
G
T
K
K
A
R
F
K
G
K
G
W
L
N
A
Q
L
S
V
I
F
F
K
L
L
E
E
H
G
I
K
T
H
F
I
G
V
A
G
G
N
R
L
I
V
E
K
L
D
M
Y
P
L
E
V
V
V
R
N
V
V
A
G
S
L
K
K
R
L
P
L
P
E
G
Y
E
L
P
E
P
I
V
E
L
Y
Y
K
N
D
E
L
H
D
P
M
I
N
Y
Y
H
A
K
V
L
G
I
S
L
D
-
E
I
K
K
I
E
E
I
A
L
K
V
N
E
I
L
K
D
Y
L
A
K
K
G
I
I
L
V
D
F
K
L
E
F
G
---
K
D
K
N
---
G
D
I
V
L
A
D
E
I
S
P
D
T
C
R
F
W
D
A
-
K
-
T
-
K
-
R
S
L
D
K
D
V
F
R
F
D
K
G
D
L
I
E
A
Y
K
E
I
Y
E
R
I
-----
18
PsiBlast_PDB
76.07
44%
-55
- C2 -
-
2YZL
1
PUR7_METJA
A:
[9-239]
L
K
K
-
Q
P
-
L
Y
S
G
K
A
K
S
I
Y
E
I
D
D
D
K
V
L
I
E
-
F
R
D
D
I
T
A
G
-
G
A
K
H
D
V
K
Q
G
K
G
Y
L
N
A
L
I
S
S
K
L
F
E
A
L
E
E
N
G
V
K
T
H
Y
I
K
Y
I
E
P
R
Y
M
I
A
K
K
V
E
I
I
P
I
E
V
I
V
R
N
I
A
A
G
S
L
C
R
R
Y
P
F
E
E
G
K
E
L
P
F
P
I
V
Q
F
D
Y
K
N
D
E
Y
G
D
P
M
L
N
E
D
I
A
V
A
L
G
L
A
T
R
E
E
L
N
K
I
K
E
I
A
L
K
V
N
E
V
L
K
K
L
F
D
E
K
G
I
I
L
V
D
F
K
I
E
I
G
---
K
D
R
E
---
G
N
L
L
V
A
D
E
I
S
P
D
T
M
R
L
W
D
K
-
E
-
T
-
R
-
D
V
L
D
K
D
V
F
R
K
D
L
G
D
V
I
A
K
Y
R
I
V
A
E
R
L
-----
15
PsiBlast_PDB
76.06
47%
-68
- C2 -
-
4O7Y
1
PUR7_PYRHO
A:
[11-231]
-----------
K
A
K
K
M
I
P
I
D
D
D
K
L
I
M
E
-
F
K
D
D
A
T
A
F
D
G
T
K
K
A
R
F
K
G
K
G
W
L
N
A
Q
L
S
V
I
F
F
K
L
L
E
E
H
G
I
K
T
H
F
I
G
V
A
G
G
N
R
L
I
V
E
K
L
D
M
Y
P
L
E
V
V
V
R
N
V
V
A
G
S
L
K
K
R
L
P
L
P
E
G
Y
E
L
P
E
P
I
V
E
L
Y
Y
K
N
D
E
L
H
D
P
M
I
N
Y
Y
H
A
K
V
L
G
I
S
L
D
-
E
I
K
K
I
E
E
I
A
L
K
V
N
E
I
L
K
D
Y
L
A
K
K
G
I
I
L
V
D
F
K
L
E
F
G
---
K
D
K
N
---
G
D
I
V
L
A
D
E
I
S
P
D
T
C
R
F
W
D
A
-
K
-
T
-
K
-
R
S
L
D
K
D
V
F
R
F
D
K
G
D
L
I
E
A
Y
K
E
I
Y
E
R
I
-----
9
PsiBlast_PDB
75.97
47%
-60
- C2 -
-
4O7N
1
PUR7_PYRHO
A:
[7-231]
-------
V
Y
E
G
K
A
K
K
M
I
P
I
D
D
D
K
L
I
M
E
-
F
K
D
D
A
T
A
F
D
G
T
K
K
A
R
F
K
G
K
G
W
L
N
A
Q
L
S
V
I
F
F
K
L
L
E
E
H
G
I
K
T
H
F
I
G
V
A
G
G
N
R
L
I
V
E
K
L
D
M
Y
P
L
E
V
V
V
R
N
V
V
A
G
S
L
K
K
R
L
P
L
P
E
G
Y
E
L
P
E
P
I
V
E
L
Y
Y
K
N
D
E
L
H
D
P
M
I
N
Y
Y
H
A
K
V
L
G
I
S
L
D
-
E
I
K
K
I
E
E
I
A
L
K
V
N
E
I
L
K
D
Y
L
A
K
K
G
I
I
L
V
D
F
K
L
E
F
G
---
K
D
K
N
---
G
D
I
V
L
A
D
E
I
S
P
D
T
C
R
F
W
D
A
-
K
-
T
-
K
-
R
S
L
D
K
D
V
F
R
F
D
K
G
D
L
I
E
A
Y
K
E
I
Y
E
R
I
-----
56
HHSearch
75.82
45%
-54
* C2 *
-
4O7N
1
PUR7_PYRHO
A:
[6-235]
-----
E
-
V
Y
E
G
K
A
K
K
M
I
P
I
D
-
D
D
K
L
I
M
E
F
K
D
D
A
T
A
F
D
G
T
K
K
A
R
F
K
G
K
G
W
L
N
A
Q
L
S
V
I
F
F
K
L
L
E
E
H
G
I
K
T
H
F
I
G
V
A
G
G
N
R
L
I
V
E
K
L
D
M
Y
P
L
E
V
V
V
R
N
V
V
A
G
S
L
K
K
R
L
P
L
P
E
G
Y
E
L
P
E
P
I
V
E
L
Y
Y
K
N
D
E
L
H
D
P
M
I
N
Y
Y
H
A
K
V
L
G
-
I
S
L
D
E
I
K
K
I
E
E
I
A
L
K
V
N
E
I
L
K
D
Y
L
A
K
K
G
I
I
L
V
D
F
K
L
E
F
G
---
K
D
K
N
---
G
D
I
V
L
A
D
E
I
S
P
D
T
C
R
F
W
D
A
K
T
-
K
-
R
-
S
-
L
D
K
D
V
F
R
F
D
K
G
D
L
I
E
A
Y
K
E
I
Y
E
R
I
-
T
G
E
K
13
PsiBlast_PDB
75.60
47%
-66
- C2 -
-
4O7V
2
PUR7_PYRHO
A:
[11-231]
-----------
K
A
K
K
M
I
P
I
D
D
D
K
L
I
M
E
-
F
K
D
D
A
T
A
F
D
G
T
K
K
A
R
F
K
G
K
G
W
L
N
A
Q
L
S
V
I
F
F
K
L
L
E
E
H
G
I
K
T
H
F
I
G
V
A
G
G
N
R
L
I
V
E
K
L
D
M
Y
P
L
E
V
V
V
R
N
V
V
A
G
S
L
K
K
R
L
P
L
P
E
G
Y
E
L
P
E
P
I
V
E
L
Y
Y
K
N
D
E
L
H
D
P
M
I
N
Y
Y
H
A
K
V
L
G
I
S
L
D
-
E
I
K
K
I
E
E
I
A
L
K
V
N
E
I
L
K
D
Y
L
A
K
K
G
I
I
L
V
D
F
K
L
E
F
G
---
K
D
K
N
---
G
D
I
V
L
A
D
E
I
S
P
D
T
C
R
F
W
D
A
-
K
-
T
-
K
-
R
S
L
D
K
D
V
F
R
F
D
K
G
D
L
I
E
A
Y
K
E
I
Y
E
R
I
-----
12
PsiBlast_PDB
75.53
47%
-67
- C2 -
-
4O7T
3
PUR7_PYRHO
A:
[12-231]
------------
A
K
K
M
I
P
I
D
D
D
K
L
I
M
E
-
F
K
D
D
A
T
A
F
D
G
T
K
K
A
R
F
K
G
K
G
W
L
N
A
Q
L
S
V
I
F
F
K
L
L
E
E
H
G
I
K
T
H
F
I
G
V
A
G
G
N
R
L
I
V
E
K
L
D
M
Y
P
L
E
V
V
V
R
N
V
V
A
G
S
L
K
K
R
L
P
L
P
E
G
Y
E
L
P
E
P
I
V
E
L
Y
Y
K
N
D
E
L
H
D
P
M
I
N
Y
Y
H
A
K
V
L
G
I
S
L
D
-
E
I
K
K
I
E
E
I
A
L
K
V
N
E
I
L
K
D
Y
L
A
K
K
G
I
I
L
V
D
F
K
L
E
F
G
---
K
D
K
N
---
G
D
I
V
L
A
D
E
I
S
P
D
T
C
R
F
W
D
A
-
K
-
T
-
K
-
R
S
L
D
K
D
V
F
R
F
D
K
G
D
L
I
E
A
Y
K
E
I
Y
E
R
I
-----
25
PsiBlast_CBE
73.75
51%
-47
- C2 -
-
3NUA
3
PUR7_CLOP1
B:
[9-237]
----
E
M
-
L
Y
E
G
K
A
K
K
I
Y
A
T
D
K
E
D
M
V
I
V
H
Y
K
D
D
A
T
A
F
N
G
E
K
K
A
Q
I
E
S
K
G
V
L
N
N
E
I
T
S
L
I
F
E
M
L
N
K
E
G
I
K
T
H
F
V
E
K
L
N
D
R
D
Q
L
C
K
K
V
E
I
V
P
L
E
V
I
V
R
N
V
A
A
G
S
M
A
K
R
L
G
L
E
E
G
Y
E
L
K
T
T
V
F
E
L
S
Y
K
D
D
S
L
G
D
P
L
I
N
D
Y
H
A
V
G
I
G
A
T
T
F
E
E
L
N
K
I
Y
E
I
T
A
K
V
N
E
I
L
K
E
A
F
K
K
Q
N
I
N
L
I
D
F
K
L
E
F
G
----
R
Y
N
---
G
E
I
L
L
A
D
E
I
S
P
D
T
C
R
F
W
D
A
T
T
-
G
-
E
-
K
-
M
D
K
D
R
F
R
R
D
M
G
N
V
I
N
G
Y
R
E
V
L
N
R
L
-
R
---
52
HHSearch
73.66
52%
-47
- C2 -
-
3NUA
3
PUR7_CLOP1
B:
[7-237]
-
Q
L
-
E
M
-
L
Y
E
G
K
A
K
K
I
Y
A
T
D
K
E
D
M
V
I
V
H
Y
K
D
D
A
T
A
F
N
G
E
K
K
A
Q
I
E
S
K
G
V
L
N
N
E
I
T
S
L
I
F
E
M
L
N
K
E
G
I
K
T
H
F
V
E
K
L
N
D
R
D
Q
L
C
K
K
V
E
I
V
P
L
E
V
I
V
R
N
V
A
A
G
S
M
A
K
R
L
G
L
E
E
G
Y
E
L
K
T
T
V
F
E
L
S
Y
K
D
D
S
L
G
D
P
L
I
N
D
Y
H
A
V
G
I
G
A
T
T
F
E
E
L
N
K
I
Y
E
I
T
A
K
V
N
E
I
L
K
E
A
F
K
K
Q
N
I
N
L
I
D
F
K
L
E
F
G
---
R
Y
N
----
G
E
I
L
L
A
D
E
I
S
P
D
T
C
R
F
W
D
A
T
T
-
G
-
E
-
K
-
M
D
K
D
R
F
R
R
D
M
G
N
V
I
N
G
Y
R
E
V
L
N
R
L
-
R
---
6
PsiBlast_PDB
73.36
45%
-44
- C2 -
-
3KRE
10
PUR7_EHRCR
A:
[26-260]
----
E
K
-
I
Y
E
G
K
A
K
I
I
F
A
T
L
N
P
L
E
V
I
Q
H
F
K
D
E
I
T
A
F
N
N
K
K
A
A
I
I
H
E
K
G
I
L
N
N
Y
I
S
S
F
L
M
K
K
L
I
D
K
G
I
K
T
H
F
I
S
L
L
N
Q
R
E
Q
L
V
K
K
I
T
I
I
P
I
E
V
V
I
R
N
L
A
A
G
N
F
S
K
R
F
Q
I
A
D
G
T
P
F
K
S
P
I
I
E
F
Y
Y
K
N
D
E
L
S
D
P
M
V
S
E
G
H
I
L
S
F
Q
W
L
T
N
Q
E
L
E
K
I
K
I
L
S
L
K
I
N
N
I
L
S
E
L
F
F
N
V
G
I
K
L
V
D
F
K
L
E
F
G
K
L
H
N
D
E
Q
---
S
D
L
F
L
A
D
E
I
S
P
D
T
C
R
L
W
D
I
-
S
-
T
-
N
K
R
-
L
D
K
D
R
Y
R
L
N
L
G
N
V
I
E
G
Y
R
E
V
A
H
K
L
-
N
A
I
-
20
PsiBlast_PDB
73.26
47%
-68
- C2 -
-
4O81
3
PUR7_PYRHO
A:
[12-231]
------------
A
K
K
M
I
P
I
D
D
D
K
L
I
-
M
E
F
K
D
D
A
T
A
F
D
G
T
K
K
A
R
F
K
G
K
G
W
L
N
A
Q
L
S
V
I
F
F
K
L
L
E
E
H
G
I
K
T
H
F
I
G
V
A
G
G
N
R
L
I
V
E
K
L
D
M
Y
P
L
E
V
V
V
R
N
V
V
A
G
S
L
K
K
R
L
P
L
P
E
G
Y
E
L
P
E
P
I
V
E
L
Y
Y
K
N
D
E
L
H
D
P
M
I
N
Y
Y
H
A
K
V
L
G
I
S
L
D
-
E
I
K
K
I
E
E
I
A
L
K
V
N
E
I
L
K
D
Y
L
A
K
K
G
I
I
L
V
D
F
K
L
E
F
G
---
K
D
K
N
---
G
D
I
V
L
A
D
E
I
S
P
D
T
C
R
F
W
D
A
-
K
-
T
-
K
-
R
S
L
D
K
D
V
F
R
F
D
K
G
D
L
I
E
A
Y
K
E
I
Y
E
R
I
-----
26
PsiBlast_CBE
73.08
44%
-57
- C2 -
-
2Z02
2
PUR7_METJA
B:
[9-239]
L
K
K
-
Q
P
-
L
Y
S
G
K
A
K
S
I
Y
E
I
D
D
D
K
V
L
I
E
-
F
R
D
D
I
T
A
G
N
G
A
K
H
D
V
K
Q
G
K
G
Y
L
N
A
L
I
S
S
K
L
F
E
A
L
E
E
N
G
V
K
T
H
Y
I
K
Y
I
E
P
R
Y
M
I
A
K
K
V
E
I
I
P
I
E
V
I
V
R
N
I
A
A
G
S
L
C
R
R
Y
P
F
E
E
G
K
E
L
P
F
P
I
V
Q
F
D
Y
K
N
D
E
Y
G
D
P
M
L
N
E
D
I
A
V
A
L
G
L
A
T
R
E
E
L
N
K
I
K
E
I
A
L
K
V
N
E
V
L
K
K
L
F
D
E
K
G
I
I
L
V
D
F
K
I
E
I
G
---
K
D
R
E
---
G
N
L
L
V
A
D
E
I
S
P
D
T
M
R
L
W
D
K
-
E
-
T
-
R
-
D
V
L
D
K
D
V
F
R
K
D
L
G
D
V
I
A
K
Y
R
I
V
A
E
R
L
-----
10
PsiBlast_PDB
72.90
47%
-62
- C2 -
-
4O7R
2
PUR7_PYRHO
A:
[11-231]
-----------
K
A
K
K
M
I
P
I
D
D
D
K
L
I
M
E
-
F
K
D
D
A
T
A
F
D
G
T
K
K
A
R
F
K
G
K
G
W
L
N
A
Q
L
S
V
I
F
F
K
L
L
E
E
H
G
I
K
T
H
F
I
G
V
A
G
G
N
R
L
I
V
E
K
L
D
M
Y
P
L
E
V
V
V
R
N
V
V
A
G
S
L
K
K
R
L
P
L
P
E
G
Y
E
L
P
E
P
I
V
E
L
Y
Y
K
N
D
E
L
H
D
P
M
I
N
Y
Y
H
A
K
V
L
G
I
S
L
D
-
E
I
K
K
I
E
E
I
A
L
K
V
N
E
I
L
K
D
Y
L
A
K
K
G
I
I
L
V
D
F
K
L
E
F
G
---
K
D
K
N
---
G
D
I
V
L
A
D
E
I
S
P
D
T
C
R
F
W
D
A
-
K
-
T
-
K
-
R
S
L
D
K
D
V
F
R
F
D
K
G
D
L
I
E
A
Y
K
E
I
Y
E
R
I
-----
5
PsiBlast_PDB
72.75
51%
-48
- C2 -
-
3NUA
4
PUR7_CLOP1
A:
[9-237]
----
E
M
-
L
Y
E
G
K
A
K
K
I
Y
A
T
D
K
E
D
M
V
I
V
H
Y
K
D
D
A
T
A
F
N
G
E
K
K
A
Q
I
E
S
K
G
V
L
N
N
E
I
T
S
L
I
F
E
M
L
N
K
E
G
I
K
T
H
F
V
E
K
L
N
D
R
D
Q
L
C
K
K
V
E
I
V
P
L
E
V
I
V
R
N
V
A
A
G
S
M
A
K
R
L
G
L
E
E
G
Y
E
L
K
T
T
V
F
E
L
S
Y
K
D
D
S
L
G
D
P
L
I
N
D
Y
H
A
V
G
I
G
A
T
T
F
E
E
L
N
K
I
Y
E
I
T
A
K
V
N
E
I
L
K
E
A
F
K
K
Q
N
I
N
L
I
D
F
K
L
E
F
G
----
R
Y
N
---
G
E
I
L
L
A
D
E
I
S
P
D
T
C
R
F
W
D
A
T
T
-
G
-
E
-
K
-
M
D
K
D
R
F
R
R
D
M
G
N
V
I
N
G
Y
R
E
V
L
N
R
L
-
R
---
19
PsiBlast_PDB
72.27
44%
-54
- C2 -
-
2Z02
1
PUR7_METJA
A:
[9-239]
L
K
K
-
Q
P
-
L
Y
S
G
K
A
K
S
I
Y
E
I
D
D
D
K
V
L
I
E
-
F
R
D
D
I
T
A
G
N
G
A
K
H
D
V
K
Q
G
K
G
Y
L
N
A
L
I
S
S
K
L
F
E
A
L
E
E
N
G
V
K
T
H
Y
I
K
Y
I
E
P
R
Y
M
I
A
K
K
V
E
I
I
P
I
E
V
I
V
R
N
I
A
A
G
S
L
C
R
R
Y
P
F
E
E
G
K
E
L
P
F
P
I
V
Q
F
D
Y
K
N
D
E
Y
G
D
P
M
L
N
E
D
I
A
V
A
L
G
L
A
T
R
E
E
L
N
K
I
K
E
I
A
L
K
V
N
E
V
L
K
K
L
F
D
E
K
G
I
I
L
V
D
F
K
I
E
I
G
---
K
D
R
E
---
G
N
L
L
V
A
D
E
I
S
P
D
T
M
R
L
W
D
K
-
E
-
T
-
R
-
D
V
L
D
K
D
V
F
R
K
D
L
G
D
V
I
A
K
Y
R
I
V
A
E
R
L
-----
53
HHSearch
72.02
46%
-46
- C2 -
-
3KRE
10
PUR7_EHRCR
A:
[26-260]
----
E
K
-
I
Y
E
G
K
A
K
I
I
F
A
T
L
N
P
L
E
V
I
Q
H
F
K
D
E
I
T
A
F
N
N
K
K
A
A
I
I
H
E
K
G
I
L
N
N
Y
I
S
S
F
L
M
K
K
L
I
D
K
G
I
K
T
H
F
I
S
L
L
N
Q
R
E
Q
L
V
K
K
I
T
I
I
P
I
E
V
V
I
R
N
L
A
A
G
N
F
S
K
R
F
Q
I
A
D
G
T
P
F
K
S
P
I
I
E
F
Y
Y
K
N
D
E
L
S
D
P
M
V
S
E
G
H
I
L
S
F
Q
W
L
T
N
Q
E
L
E
K
I
K
I
L
S
L
K
I
N
N
I
L
S
E
L
F
F
N
V
G
I
K
L
V
D
F
K
L
E
F
G
---
K
L
H
N
DEQ
S
D
L
F
L
A
D
E
I
S
P
D
T
C
R
L
W
D
I
S
T
-
N
-
K
-
R
-
L
D
K
D
R
Y
R
L
N
L
G
N
V
I
E
G
Y
R
E
V
A
H
K
L
-
N
A
I
-
50
HHSearch
69.31
41%
-33
- C2 -
-
2GQS
3
PUR7_ECOLI
B:
[2-235]
Q
K
Q
-
A
E
-
L
Y
R
G
K
A
K
T
V
Y
S
T
E
N
P
D
L
L
V
L
E
F
R
N
D
T
S
A
G
D
G
A
R
I
E
Q
F
D
R
K
G
M
V
N
N
K
F
N
Y
F
I
M
S
K
L
A
E
A
G
I
P
T
Q
M
E
R
L
L
S
D
T
E
C
L
V
K
K
L
D
M
V
P
V
E
C
V
V
R
N
R
A
A
G
S
L
V
K
R
L
G
I
E
E
G
I
E
L
N
P
P
L
F
D
L
F
L
K
N
D
A
M
H
D
P
M
V
N
E
S
Y
C
E
T
F
G
W
V
S
K
E
N
L
A
R
M
K
E
L
T
Y
K
A
N
D
V
L
K
K
L
F
D
D
A
G
L
I
L
V
D
F
K
L
E
F
G
---
L
Y
-
K
---
G
E
V
V
L
G
D
E
F
S
P
D
G
S
R
L
W
D
K
E
T
-
L
-
E
-
K
-
M
D
K
D
R
F
R
Q
S
L
G
G
L
I
E
A
Y
E
A
V
A
R
R
L
-
G
V
Q
-
37
Fugue
60.54
42%
61
- C2 -
-
2GQS
3
PUR7_ECOLI
A:
[1-237]
M
Q
K
Q
A
E
-
L
Y
R
G
K
A
K
T
V
Y
S
T
E
N
P
D
L
L
V
L
E
F
R
N
D
T
S
A
G
D
G
A
R
I
E
Q
F
D
R
K
G
M
V
N
N
K
F
N
Y
F
I
M
S
K
L
A
E
A
G
I
P
T
Q
M
E
R
L
L
S
D
T
E
C
L
V
K
K
L
D
M
V
P
V
E
C
V
V
R
N
R
A
A
G
S
L
V
K
R
L
G
I
E
E
G
I
E
L
N
P
P
L
F
D
L
F
L
K
N
D
A
M
H
D
P
M
V
N
E
S
Y
C
E
T
F
G
W
V
S
K
E
N
L
A
R
M
K
E
L
T
Y
K
A
N
D
V
L
K
K
L
F
D
D
A
G
L
I
L
V
D
F
K
L
E
F
G
---
L
Y
-
K
---
G
E
V
V
L
G
D
E
F
S
P
D
G
S
R
L
W
D
K
-
E
T
L
-
E
-
K
-
M
D
K
D
R
F
R
Q
S
L
G
G
L
I
E
A
Y
E
A
V
A
R
R
L
G
V
Q
L
D
28
PsiBlast_CBE
59.54
42%
63
- C2 -
-
2GQS
3
PUR7_ECOLI
A:
[1-232]
M
Q
K
-
Q
A
E
L
Y
R
G
K
A
K
T
V
Y
S
T
E
N
P
D
L
L
V
L
E
F
R
N
D
T
S
A
G
D
G
A
R
I
E
Q
F
D
R
K
G
M
V
N
N
K
F
N
Y
F
I
M
S
K
L
A
E
A
G
I
P
T
Q
M
E
R
L
L
S
D
T
E
C
L
V
K
K
L
D
M
V
P
V
E
C
V
V
R
N
R
A
A
G
S
L
V
K
R
L
G
I
E
E
G
I
E
L
N
P
P
L
F
D
L
F
L
K
N
D
A
M
H
D
P
M
V
N
E
S
Y
C
E
T
F
G
W
V
S
K
E
N
L
A
R
M
K
E
L
T
Y
K
A
N
D
V
L
K
K
L
F
D
D
A
G
L
I
L
V
D
F
K
L
E
F
G
---
L
Y
K
----
G
E
V
V
L
G
D
E
F
S
P
D
G
S
R
L
W
D
K
-
E
-
T
L
E
-
K
-
M
D
K
D
R
F
R
Q
S
L
G
G
L
I
E
A
Y
E
A
V
A
R
R
L
-----
27
PsiBlast_CBE
58.67
42%
63
- C2 -
-
2GQS
3
PUR7_ECOLI
B:
[1-232]
M
Q
K
-
Q
A
E
L
Y
R
G
K
A
K
T
V
Y
S
T
E
N
P
D
L
L
V
L
E
F
R
N
D
T
S
A
G
D
G
A
R
I
E
Q
F
D
R
K
G
M
V
N
N
K
F
N
Y
F
I
M
S
K
L
A
E
A
G
I
P
T
Q
M
E
R
L
L
S
D
T
E
C
L
V
K
K
L
D
M
V
P
V
E
C
V
V
R
N
R
A
A
G
S
L
V
K
R
L
G
I
E
E
G
I
E
L
N
P
P
L
F
D
L
F
L
K
N
D
A
M
H
D
P
M
V
N
E
S
Y
C
E
T
F
G
W
V
S
K
E
N
L
A
R
M
K
E
L
T
Y
K
A
N
D
V
L
K
K
L
F
D
D
A
G
L
I
L
V
D
F
K
L
E
F
G
---
L
Y
K
----
G
E
V
V
L
G
D
E
F
S
P
D
G
S
R
L
W
D
K
-
E
-
T
L
E
-
K
-
M
D
K
D
R
F
R
Q
S
L
G
G
L
I
E
A
Y
E
A
V
A
R
R
L
-----