@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : spr0069: (2017-12-14 )
MTYSHIYQVLFLPKLSIKRWHFLGLVLVNFALSYLSHFELFMVQWKHVIQII
Atome Classification :
(14 SA)
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------......-...10--------........20..-----......---------30....-....40.----.......50.----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M
T
Y
S
H
I
-
Y
Q
V
LF--------LPKLSI
K
R
W
H
F
L
-----
G
L
V
L
V
N
---------
F
A
L
S
Y
L
-
S
H
F
E
L
F
M
----
V
Q
W
K
H
V
I
QII----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
Fugue
68.71
22%
-
* C4 *
-
4XR7
-
PAN3_YEAST
B:
[225-680]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MHSLLQYRSADQLFIPNNIREDLTKKNLSILQVFPSSGKVIPSIVQDYFNLVPLNFNNKTTLFKVFSNYDGKAYVLKRLPNIDKSMNPNKISKIYQIWSKINCTNLIKFRDIFQTTKFGDLSIC
L
V
F
D
Y
------
Y
--------
P
N
S
L
S
L
Y
D
Y
H
F
V
-----
N
F
P
--
K
---------
F
P
I
T
-
N
-
N
Y
L
W
I
Y
L
----
V
Q
L
T
N
V
I
N
S
I
HSQNLSIGNTLNWRKVLITGDPGRIKLSHCNFMDLLFNDDTDTVVSSTIEGQQQLDYKYLGELLFNLSINIENSNNNTAPKEYRLEEITPQSIDDMRQIDDKFKDVLKYLISDNGDSKKSIHDLTSHFYDKMFMVLESSQTYTEYMESVLSRELENGRLFRLVNKLNCIFGRIESRIDINWSESGTKFPIILFYDYVFHQVDSNGKPIMDLTHVLRCLNKLDAGIQEKLMLVTPDELNCIIISYKELKDLIESTFRSITQH-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
Fugue
54.90
21%
5
- C4 -
-
1GYZ
-
RL20_AQUAE
A:
[59-118]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WI
A
R
I
N
A
A
V
RAYG
L
N
Y
S
T
F
-
I
N
G
L
K
--------
K
A
G
I
E
L
D
R
----------
K
I
L
A
D
---------
M
A
V
R
D
P
-
Q
A
F
E
Q
V
V
----
N
K
V
K
E
A
L
Q
V
Q
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
53.43
34%
-215
* C3 *
-
1UX6
-
A:
[185-225]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
V
D
F
S
-----
G
T
F
F
I
N
TE
R
D
D
D
Y
A
G
F
V
F
G
Y
Q
-
S
S
S
R
F
Y
V
----
V
M
W
K
Q
V
T
Q
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
Fugue
46.09
21%
-104
- C4 -
-
5LTE
2
?
A:
[5-337]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FKPLESYREDFS
F
R
N
S
P
A
A
I
A
R
FPFPFPED
Q
Y
M
Y
S
VNLEPAVSRDPGSVFEHQ
F
D
V
D
EH
Y
V
S
E
M
A
E
R
A
R
V
L
E
L
D
P
-
G
R
C
L
V
--------
M
P
H
M
A
Q
A
A
W
D
T
L
-----
A
M
L
M
E
H
---------
L
A
R
D
Y
P
-
Q
H
F
R
L
T
R
Q
GDA
W
H
W
Q
N
L
A
L
G
I
D
Q
R
F
T
FGDPASLPCE
P
L
E
Y
I
T
R
Q
M
Q
G
D
F
A
V
L
D
Q
R
DGDLFMD
A
G
M
V
TCPADWSLRFDAGMS
F
K
Q
W
H
SPVPMAHQMG
V
F
D
R
A
L
K
Y
L
L
N
IQVG
A
P
V
R
R
L
N
W
T
L
T
I
N
PRLDTSPETYHEW
G
N
D
R
G
K
VTPDNVGRL
V
H
L
R
V
E
L
Q
L
M
A
R
L
P
RSN
A
L
L
F
G
I
R
T
Y
L
I
S
L
D
E
L
V
SN
P
A
W
A
Q
R
L
H
R
V
M
R
D
LP
D
P
I
A
D
Y
K
GITRY
R
Q
T
L
V
D
W
L
R
R
F
DPE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
45.46
40%
-402
- C2 -
-
5MMI
-
RK3_SPIOL
D:
[212-221]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
K
R
H
N
F
K
-----
R
G
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
Fugue
44.46
25%
-42
- C4 -
-
5IJL
-
DP2L_PYRAB
A:
[9-1044]
P
K
E
M
E
E
Y
F
E
M
L
Q
R
E
I
D
K
A
Y
E
I
A
K
K
A
R
A
Q
GKDPSLDVE
I
P
Q
A
TD
M
A
G
R
V
E
S
L
VGPPG
V
A
K
R
I
R
E
L
V
K
E
YG
K
E
I
A
A
L
K
I
V
D
E
I
I
E
GKFGDLGS
R
E
K
Y
A
E
Q
A
V
R
T
A
L
A
I
L
T
EGIVSAPIEGIA
N
V
K
I
K
R
NTWADN
S
E
Y
L
A
L
Y
Y
A
GPIRSSG
G
T
A
Q
A
L
S
V
L
V
G
D
Y
V
R
R
K
L
GLD
R
F
K
P
S
E
K
H
I
E
R
M
V
E
E
V
D
L
Y
H
R
AVTRLQ
Y
H
P
S
P
E
E
V
R
L
A
M
R
N
IPIEITGEATDDVEVSHRDVPGVETNQLR
G
G
A
I
L
V
L
AEGVLQK
A
K
K
L
V
K
Y
I
D
K
M
GIEGW
E
W
L
K
E
F
V
E
A
K
E
K
GVDMG
F
Y
Y
S
L
Y
Q
K
F
K
E
EPLFSDPSKPGGFR
L
R
Y
G
RSWGIN
P
A
T
M
I
L
VG
A
V
V
T
P
V
TT
I
E
G
P
I
V
K
L
KDG
S
V
L
R
V
DD
Y
N
L
A
L
K
V
R
EDVEEILYL
G
D
A
V
I
A
FGDQTLLPANYC
E
E
W
W
I
L
E
F
V
K
A
L
K
E
I
YE
V
H
L
E
P
F
T
E
N
E
E
E
S
I
E
E
A
S
D
Y
L
EID
P
E
F
L
K
E
M
L
R
DPLRVKPP
V
E
L
A
I
H
F
S
E
V
L
G
I
P
L
H
P
-
Y
Y
T
L
Y
--------
W
N
S
V
E
P
K
D
V
E
K
L
-----
W
R
L
L
K
N
---------
Y
A
E
I
E
W
-
S
N
F
R
--------
G
I
K
F
A
K
K
I
V
I
S
QEKLGDS
K
R
T
L
E
L
L
G
L
P
H
T
V
R
DG
N
V
I
V
D
Y
P
W
A
A
A
L
LTPLGNLN
W
E
F
M
A
K
P
LYA
T
I
D
I
I
N
E
NNE
I
K
L
R
DRGISWIGKPPVQVLFPIGLAGGSSRD
I
K
K
A
A
E
E
G
K
V
A
E
V
E
I
A
F
F
K
C
PKCGHVGPEHLCPNCG
T
R
K
E
L
L
W
V
C
PRCN
A
E
Y
P
E
S
Q
A
E
G
Y
NYTCPKCN
V
K
L
R
PYAK
R
K
I
R
P
S
E
L
L
N
R
A
M
E
N
V
KVYGVD
K
L
K
G
V
MGMTSGWKMPEP
L
E
K
G
L
L
R
A
K
N
D
V
Y
V
F
KDG
T
I
R
F
D
A
T
D
A
P
I
THFRPREIGVS
V
E
K
L
R
E
L
GYTHDFEGKPLVSED
Q
I
V
E
L
K
PQ
D
I
I
L
S
K
E
A
G
R
Y
L
L
K
V
A
K
F
V
D
D
L
L
E
KFYG
L
P
R
F
YNAEKMEDLIG
H
L
V
I
G
L
A
P
HTS
A
G
I
V
G
R
I
IGFVDAL
V
G
Y
A
H
PYFHA
A
K
R
R
N
C
DGD
E
D
A
V
M
L
L
L
D
A
L
L
NFSRYYLPEKRGGKMDAPL
V
I
T
TRLDPRYYP
L
E
F
Y
E
A
T
Y
E
LKS
P
K
E
L
V
G
V
I
E
R
V
E
D
4
HHSearch
39.69
40%
-190
- C1 -
-
5O60
-
?
D:
[126-135]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
M
K
R
H
G
F
R
-----
G
Q
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
Fugue
37.00
15%
11
- C4 -
-
2EO2
-
A:
[1-71]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GSSGSSGST
Q
T
D
K
A
L
-
Y
N
R
L
V
PLVNG
V
R
E
F
S
E
I
Q
L
S
R
L
K
K
L
-----
G
I
H
K
T
D
---------
P
S
T
L
T
E
-
E
E
V
R
K
F
A
----
R
L
N
I
D
P
A
T
I
T
WQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
Fugue
36.99
20%
-180
- C3 -
-
4Q51
-
?
A:
[11-274]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VFIQ
V
G
A
L
A
D
G
F
APEAN
T
L
A
P
V
DALVG
R
T
L
A
L
E
D
ASGA
W
R
V
H
T
F
E
PG
A
L
Q
W
R
DAATD
T
G
G
R
A
P
C
R
V
T
R
LRDG
L
Y
F
V
D
Y
I
DTTARA
T
S
V
S
L
V
I
DLDNG
V
W
T
S
V
V
G
T
L
P
T
E
A
D
T
R
ID
A
F
T
R
V
A
R
GLPLTA
V
D
A
Q
F
R
H
G
T
L
GGHARPGP
L
H
A
P
T
RELIG
K
R
T
M
Y
R
Y
S
P
T
E
C
-
Y
E
H
I
Y
--------
L
N
E
-
N
F
Y
A
W
Q
C
L
QGVEG
G
L
A
D
V
D
---------
R
C
H
Y
F
K
M
A
D
-
E
L
Y
L
----
F
V
W
R
E
K
V
V
P
T
L
G
V
V
L
I
D
LAQR
K
T
D
G
K
I
F
G
Y
QGGDF
G
T
L
S
N
F
Q
I
G
A
Y
A
Q
V
L
N
E
T
V
H
P------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
HHSearch
29.63
13%
-176
- C4 -
-
4AVM
1
BIN2_HUMAN
A:
[187-225]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
P
I
L
Y
N
S
R
I
G
C
Y
-----
V
T
I
F
Q
N
---------
I
S
N
L
R
D
-
V
F
Y
R
E
M
S
----
K
L
N
H
N
L
Y
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
29.08
19%
-327
- C4 -
-
2HGK
-
YQCC_ECOLI
A:
[45-60]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
E
P
L
E
W
-
L
Q
W
V
L
--------
I
P
R
M
H
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
Fugue
27.79
20%
8
- C4 -
-
1P9C
-
PSMD4_HUMAN
A:
[263-307]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
T
I
S
Q
Q
E
F
G
R
T
G
--------
L
P
D
L
S
S
M
T
-------------
E
E
---------
E
Q
I
A
Y
A
-
M
Q
M
S
L
Q
G
----
A
E
F
G
Q
A
E
S
A
D
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
Fugue
23.82
9%
-91
- C4 -
-
2HEP
-
YNZC_BACSU
A:
[1-42]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
--------
I
S
N
A
K
I
A
R
I
N
E
L
-----
A
A
K
A
K
A
---------
G
V
I
T
E
E
-
E
K
A
E
Q
Q
K
----
L
R
Q
E
Y
L
K
G
F
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
HHSearch
22.76
29%
-
- C4 -
-
4OWT
-
INT3_HUMAN
A:
[369-382]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
P
R
W
A
I
I
-----
G
W
L
L
T
T
---------
C
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------