@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : spr0073: (2017-12-14 )
MIDDIGQFAIWQDRMFGQTAQHGLTNSLKDFWIFLLNIGPQLAFFCQMLRCSRSVEQGTGNHRREFNMIQQIFSHFGMTHLGQIKLVYQESIDLELLVNALNHHLLIDRLVLTPNQITIEIDRQIVHGLDLLKGRKDKEIIDIKSMFRQLELASTQQICPINQRVHHGILAFGEISDLVPAKNLPNRQD
Atome Classification :
(20 SA)
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------....--.....10........20........30...------.....40..---......50........60........70........80.......-.90---........100-....--....110---....------...120.......--------130-........140.......150-.........160.-......170........180.......------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MIDD--I
G
Q
F
A
I
W
Q
D
R
MFG
Q
T
A
Q
H
G
L
T
N
S
L
K
D
F
W
I
F
------
L
LNIG
P
Q
L
A
---
F
F
C
Q
M
L
R
CSR
S
V
EQGTGN
H
R
R
E
F
N
M
I
Q
Q
I
F
S
HFGMTHL
G
Q
I
K
L
V
Y
-QES---I
D
L
E
L
L
V
N
A
L
--
N
H
H
L
--
L
I
D
R
L
VL---TP
N
Q
------
I
T
I
E
I
D
R
Q
I
V
H
G
L
--------
D
L
--LKGRKDK
E
I
I
D
I
K
S
M
F
R
Q
L
---
E
LASTQQICP
I
N
Q
-
R
V
H
H
G
I
L
A
-
F
G
E
I
S
D
LVPAKNLPNRQD------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
62.52
34%
-
- C5 -
-
1AIN
-
ANXA1_HUMAN
A:
[52-131]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
I
K
A
A
Y
L
Q
E
T
GKP
L
D
-
E
T
L
K
K
A
L
--
T
G
H
L
E
E
V
V
L
A
L
L
K
---
T
P
A
Q
------
F
D
A
D
E
L
R
A
A
M
K
G
L
GTD
E
D
T
L
I
E
I
--
L
A
S
R
T
N
K
E
I
R
D
I
N
R
V
Y
R
E
---------------------------------------------------------------------------------------------------------------------------------------------
19
Fugue
53.42
25%
33
- C2 -
-
5H8Y
2
SIR_MAIZE
D:
[11-576]
KRS
K
V
E
I
I
K
E
K
SNFLRY
P
L
N
E
E
L
V
SAPNIN
E
S
A
V
Q
L
I
K
F
H
G
S
Y
Q
Q
T
D
RDVQK
N
Y
S
F
M
L
R
T
K
N
P
CGKVP
N
Q
L
Y
L
A
M
D
T
L
A
D
E
FGIG
T
L
R
L
T
TRQ
T
F
Q
L
H
GVLKKN
L
K
T
V
L
S
T
V
I
K
N
MGSTLGACGDLN
R
N
V
L
A
PAAPYVK
K
D
I
L
F
A
Q
Q
T
A
E
N
I
A
A
L
L
TPQSG
A
Y
Y
D
L
WVDEEP
P
E
V
T
K
A
R
N
DNGTNFPDSPEPIYGTQYLP
R
K
F
K
V
A
V
T
A
AGDNSVDILTND
I
G
V
V
V
V
S
D
DAGEPI
G
F
N
I
Y
V
GGGM
G
R
T
H
RVET
T
F
P
R
L
A
D
PL
G
Y
V
P
KED
I
L
Y
A
I
K
A
I
V
V
T
Q
R
E
NGRRDDRKYSR
M
K
Y
M
I
D
R
WG
I
D
R
F
R
A
E
V
E
K
Y
Y
G
K
K
F
E
---
S
F
R
P
L
P
E
W
Q
F
------
N
S
Y
L
G
-----------------
W
Q
E
Q
G
D
G
K
------
L
F
Y
G
V
H
V
D
N
G
R
V
G
-
G
Q
A
K
K
T
L
-
R
E
I
---
I
E
K
Y
N
L
---------------
D
V
S
I
---
T
P
N
Q
NLILCG
I
D
Q
A
W
R
E
P
I
T
T
A
L
--------
A
Q
A
G
L
L
E
P
K
D
V
D
P
L
N
L
T
A
M
A
--------
C
P
A
L
P
L
C
P
L
A
Q
T
E
A
E
R
G
I
L
P
I
L
K
R
I
R
A
V
F
N
K
V
G
I
K
D
S
E
S
V
V
V
R
I
T
GCPNGCARPYMAE
L
G
F
V
G
DGPK
S
Y
Q
I
W
L
GGTPNQS
T
L
A
E
SFMDKVKLDD
I
E
K
V
L
E
P
L
F
T
Y
W
N
G
TRQEGES
F
G
S
F
T
N
R
T
G
F
D
K
L
K
E
V
V
N
K
W
16
Fugue
50.26
13%
-133
- C3 -
-
3BJ5
-
A:
[15-144]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
V
I
E
--
F
T
E
----------
Q
T
A
P
K
I
F
G
G
E
I
K
T
H
I
L
L
------
F
L
P
--------------------------
K
S
V
S
D
Y
D
G
K
L
S
N
F
K
T
A
A
E
S
F
K
G
K
I
L
F
A
F
-
I
D
----------
S
D
H
T
--
D
N
Q
R
--
I
L
E
F
F
------------------
G
L
K
K
E
E
C
P
A
V
--------
R
L
--
I
T
L
E
E
E
M
T
K
Y
K
P
E
S
--------
E
E
L
T
A
E
R
I
T
E
F
C
H
-
R
F
L
E
G
------
K
I
K
P
H
L
M
S
Q
E
L
P
E
D
W
D
------------------------------------------------------------------------------------------------
9
HHSearch
40.96
26%
-147
- C6 -
-
3OKX
-
Y152_RHOPA
B:
[126-152]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
N
L
F
I
R
G
L
--------
D
C
--
L
D
G
T
---
P
L
V
D
L
K
P
D
R
A
E
F
---
M
----------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
39.65
50%
-109
- C1 -
-
2JQ3
-
APOC3_HUMAN
A:
[48-57]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
S
L
K
D
Y
W
S
T
------
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
HHSearch
39.21
36%
-116
- C6 -
-
2NV4
-
Y241_ARCFU
A:
[103-133]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
R
L
K
V
R
W
L
--------
D
A
--
L
D
G
S
---
P
V
I
D
I
K
K
Y
S
P
E
I
DCV
N
Q
---------------------------------------------------------------------------------------------------------------------------------------
23
Fugue
39.17
20%
-16
- C4 -
-
1NO4
-
SCAF_BPPH2
A:
[2-78]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
L
K
P
E
E
-
H
E
D
---
I
L
N
K
L
L
D
P
E
L
A
Q
S
E
R
T
--
E
A
L
Q
Q
L
R
---
V
N
Y
G
------
S
F
V
S
E
Y
N
D
L
T
K
S
H
--------
E
K
--
L
A
A
E
K
D
D
L
I
V
S
N
S
K
L
F
R
Q
I
---
G
L
T
E
K
Q
E
----------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
39.14
26%
-130
* C6 *
-
3OKX
-
Y152_RHOPA
A:
[126-152]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
N
L
F
I
R
G
L
--------
D
C
--
L
D
G
T
---
P
L
V
D
L
K
P
D
R
A
E
F
---
M
----------------------------------------------------------------------------------------------------------------------------------------
20
Fugue
38.92
8%
4
- C4 -
-
2LNU
-
?
A:
[1-185]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
D
E
D
--
T
E
D
W
E
T
Q
L
Q
A
N
R
D
E
K
D
R
F
F
S
E
H
R
Q
S
P
I
P
P
E
------
E
R
D
D
F
D
G
L
S
---
Y
F
D
P
D
P
D
Y
R
V
E
A
T
V
T
V
H
E
T
P
E
S
V
D
L
E
T
S
D
D
R
T
V
R
Y
L
H
V
A
T
L
S
F
D
L
-
D
G
E
---
S
R
D
L
H
A
F
R
Q
A
--
A
D
E
S
--
R
T
L
F
V
P
F
R
D
K
T
T
G
Q
------
Q
S
Y
D
G
G
R
Y
M
E
L
E
P
--------
D
R
--
D
L
S
D
G
D
E
I
T
L
D
F
N
L
A
Y
S
P
F
---
C
A
Y
S
D
T
F
S
C
P
L
P
P
-
E
S
N
W
--------
L
E
T
A
V
T
A
G
E
R
T
D
L
E
H
------------------------------------------------------------------------------------------------
21
Fugue
38.18
28%
-215
- C4 -
-
1LOI
1
?
?:
[1-25]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
P
L
V
D
---
F
F
C
E
--
T
C
S
K
P
W
L
V
G
W
W
D
Q
F
K
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
34.40
33%
-118
- C5 -
-
2ZXX
-
CDT1_MOUSE
C:
[243-268]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
F
E
E
R
N
V
G
Q
I
K
T
V
Y
-
P
T
S
---
Y
R
F
R
Q
E
C
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
Fugue
33.98
15%
45
- C5 -
-
2N77
-
PCP4_HUMAN
B:
[30-62]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
D
I
--------
D
M
--
D
A
P
E
T
E
R
A
A
V
A
I
Q
S
Q
F
R
K
F
---
Q
K
K
K
A
G
S
Q
S
--------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
33.21
15%
-119
- C5 -
-
1WGL
-
A:
[7-46]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
C
S
E
E
D
L
K
A
I
Q
D
M
F
P
N
M
D
Q
E
V
I
R
S
V
L
-
E
A
Q
R
--
G
N
K
D
A
A
I
N
S
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
32.13
29%
-4
- C5 -
-
5FUS
4
?
A:
[67-119]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
F
W
V
T
G
S
LVPE
L
F
N
V
G
G
D
L
S
---
F
F
V
D
A
I
R
S
G
R
R
-
D
Q
L
M
A
Y
A
R
S
C
I
D
G
V
Y
E
I
Y
T
G
F
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
Fugue
30.50
9%
-91
* C4 *
-
5LSJ
-
PMF1_HUMAN
B:
[2-174]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
I
S
R
--
V
K
L
L
D
T
M
V
D
T
F
L
Q
K
L
V
A
A
G
S
Y
Q
R
F
T
D
C
Y
K
C
------
F
Y
Q
L
Q
P
A
M
T
Q
Q
I
Y
D
K
F
I
A
Q
L
Q
T
S
I
R
E
E
I
S
D
I
K
E
E
G
N
L
E
A
V
L
N
A
L
D
K
I
V
E
E
G
K
V
R
K
---
E
P
A
---
W
R
P
S
G
I
P
E
K
D
--
L
H
S
V
--
M
A
P
Y
F
L
Q
---
Q
R
D
T
------
L
R
R
H
V
Q
K
Q
E
A
E
N
Q
--------
Q
L
--
A
D
A
V
L
A
G
R
R
Q
V
E
E
L
Q
L
Q
V
Q
---
A
Q
Q
Q
A
W
Q
A
L
H
R
E
Q
-
R
E
L
V
A
V
L
R
-
E
-----------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
28.99
41%
0
- C- -
-
2HWY
-
SMG5_HUMAN
A:
[861-938]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
Q
A
L
--
C
H
H
L
--
P
V
I
R
Q
L
A
---
T
S
G
R
------
F
I
V
I
I
P
R
T
V
I
D
G
L
--------
D
L
--
L
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
28.76
42%
-
- C5 -
-
4GWQ
-
MED22_YEAST
D:
[74-85]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
L
T
R
S
I
K
E
K
W
L
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
17.69
36%
0
- C- -
-
2WVR
-
CDT1_HUMAN
C:
[230-266]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
F
E
E
R
N
V
G
Q
I
K
T
V
Y
-
P
A
S
---
Y
R
F
R
Q
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
12.23
42%
-
- C5 -
-
3R84
-
MED22_YEAST
T:
[74-85]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
L
T
R
S
I
K
E
K
W
L
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
Fugue
7.12
21%
162
* C5 *
-
4XGC
-
F:
[38-56]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
D
Y
E
I
W
K
A
R
M
L
A
K
A
Q
A
K
L
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------