@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : spr0122: (2017-12-15 )
MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDTDENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVMCNKEIKFKAFLDYAMTLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLSQEQLQKTMFPLGHLKKPEVRKLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQPGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQGFYHDSLMSTSLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFAEPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70.-.......80........90--........100.......110.-....-.-.120.......130.......140.......150.......160.......170--..-----.....180.......190---.......200...----...---------.210.-----------.--.....220.......-----230.....-..240.......250.......260.......270.......280.......290.......300.......310.......320.-..-....330.......340.......350.......360.......370.
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MSDNS
K
T
R
V
V
V
G
MSGGVD
S
S
V
T
A
L
L
L
K
EQGY
D
V
I
G
I
F
MKNWDDTDENG
V
C
TA
T
E
D
Y
K
D
V
V
A
V
A
D
QIGI
P
Y
Y
S
-
V
NF
E
K
E
Y
W
D
R
V
F
E
Y
F
L
A
E
Y
--RAGRTPNPD
V
M
CNKEI
K
F
K
A
F
L
-
D
Y
A
M
-
T
-LGADYVATG
H
Y
A
R
VARDEDG
T
V
H
M
L
RGVDNGKD
Q
T
Y
F
L
S
Q
L
S
Q
E
Q
L
Q
K
T
M
FPLG--HL-----K
K
P
E
V
R
K
L
A
E
E
AGLSTAK---KKDST
G
I
C
F
IG
E
K
----
N
F
K
---------
N
F
L
S
N
-----------Y--LPAQPG
R
M
M
T
VDGRD-----MGEHA
G
L
M
-
Y
Y
T
IGQRGGLGIGGQHGGDNA
P
W
F
V
VGKDLSK
N
I
L
Y
V
GQGFYH
D
S
L
M
STSLEAS
Q
V
H
F
T
R
EM
P
E
E
F
T
L
E
C
T
A
K
F
R
YRQPD
S
K
V
T
V
H
-
V
K-GDK
A
E
V
I
F
AEPQRAITPG
Q
A
V
V
F
YD
G
E
E
CLGGGLIDNAYRDGQVCQYI
45
HHSearch
84.19
99%
-96
- C1 -
-
2HMA
-
MNMA_STRPN
A:
[5-376]
-
S
D
N
S
K
T
R
V
V
V
G
M
S
G
G
V
D
S
S
V
T
A
L
L
L
K
E
Q
G
Y
D
V
I
G
I
F
M
K
N
W
D
D
T
D
----
C
T
A
T
E
D
Y
K
D
V
V
A
V
A
D
Q
I
G
I
P
Y
Y
S
-
V
N
F
E
K
E
Y
W
D
R
V
F
E
Y
F
L
A
E
Y
--
R
A
G
R
T
P
N
P
D
V
M
C
N
K
E
I
K
F
K
A
F
L
-
D
Y
A
I
-
T
-
L
G
A
D
Y
V
A
T
G
H
Y
A
R
V
A
R
D
E
D
G
T
V
H
M
L
R
G
V
D
N
G
K
D
Q
T
Y
F
L
S
Q
L
S
Q
E
Q
L
Q
K
T
M
F
P
L
G
--
H
L
-----
E
K
P
E
V
R
R
L
A
E
E
A
G
L
S
T
A
K
---
K
K
D
S
T
G
I
C
F
I
G
E
K
----
N
F
K
---------
N
F
L
S
N
-----------
Y
--
L
P
A
Q
P
G
R
M
M
T
V
D
G
R
D
-----
M
G
E
H
A
G
L
M
-
Y
Y
T
I
G
Q
R
G
G
L
G
I
G
----
G
D
N
A
P
W
F
V
V
G
K
D
L
S
K
N
I
L
Y
V
G
Q
G
F
Y
H
D
S
L
M
S
T
S
L
E
A
S
Q
V
H
F
T
R
E
M
P
E
E
F
T
L
E
C
T
A
K
F
R
Y
R
Q
P
D
S
K
V
T
V
H
-
V
K
-
G
E
K
T
E
V
I
F
A
E
P
Q
R
A
I
T
P
G
Q
A
V
V
F
Y
D
G
E
E
C
L
G
G
G
L
I
D
N
A
Y
R
D
G
Q
V
C
Q
Y
I
1
PsiBlast_PDB
83.35
95%
-96
- C1 -
-
2HMA
-
MNMA_STRPN
A:
[5-376]
-
S
D
N
S
K
T
R
V
V
V
G
M
S
G
G
V
D
S
S
V
T
A
L
L
L
K
E
Q
G
Y
D
V
I
G
I
F
M
K
N
W
D
D
T
D
----
C
T
A
T
E
D
Y
K
D
V
V
A
V
A
D
Q
I
G
I
P
Y
Y
S
-
V
N
F
E
K
E
Y
W
D
R
V
F
E
Y
F
L
A
E
Y
--
R
A
G
R
T
P
N
P
D
V
M
C
N
K
E
I
K
F
K
A
F
L
-
D
Y
A
I
-
T
-
L
G
A
D
Y
V
A
T
G
H
Y
A
R
V
A
R
D
E
D
G
T
V
H
M
L
R
G
V
D
N
G
K
D
Q
T
Y
F
L
S
Q
L
S
Q
E
Q
L
Q
K
T
M
F
P
L
G
--
H
L
-----
E
K
P
E
V
R
R
L
A
E
E
A
G
L
S
T
A
K
---
K
K
D
S
T
G
I
C
F
I
G
E
K
----
N
F
K
---------
N
F
L
S
N
-----------
Y
--
L
P
A
Q
P
G
R
M
M
T
V
D
G
R
D
-----
M
G
E
H
A
G
L
M
-
Y
Y
T
I
G
Q
R
G
G
L
G
I
G
----
G
D
N
A
P
W
F
V
V
G
K
D
L
S
K
N
I
L
Y
V
G
Q
G
F
Y
H
D
S
L
M
S
T
S
L
E
A
S
Q
V
H
F
T
R
E
M
P
E
E
F
T
L
E
C
T
A
K
F
R
Y
R
Q
P
D
S
K
V
T
V
H
-
V
K
-
G
E
K
T
E
V
I
F
A
E
P
Q
R
A
I
T
P
G
Q
A
V
V
F
Y
D
G
E
E
C
L
G
G
G
L
I
D
N
A
Y
R
D
G
Q
V
C
Q
Y
I
21
PsiBlast_CBE
66.11
59%
-28
- C1 -
-
2DEU
1
MNMA_ECOLI
B:
[17-374]
----
A
K
-
K
V
I
V
G
M
S
G
G
V
D
S
S
V
S
A
W
L
L
Q
Q
Q
G
Y
Q
V
E
G
L
F
M
K
N
W
E
E
D
D
G
E
E
Y
C
T
A
A
A
D
L
A
D
A
Q
A
V
C
D
K
L
G
I
E
L
H
T
-
V
N
F
A
A
E
Y
W
D
N
V
F
E
L
F
L
A
E
Y
--
K
A
G
R
T
P
N
P
D
I
L
C
N
K
E
I
K
F
K
A
F
L
-
E
F
A
A
-
E
D
L
G
A
D
Y
I
A
T
G
H
Y
V
R
R
A
-
D
V
D
G
K
S
R
L
L
R
G
L
D
S
N
K
D
Q
S
Y
F
L
Y
T
L
S
H
E
Q
I
A
Q
S
L
F
P
V
G
--
E
L
-----
E
K
P
Q
V
R
K
I
A
E
D
L
G
L
V
T
A
K
---
K
K
D
S
T
G
I
C
F
I
G
E
R
----
K
F
R
---------
E
F
L
G
R
-----------
Y
--
L
P
A
Q
P
G
K
I
I
T
V
D
G
D
E
-----
I
G
E
H
Q
G
L
M
-
Y
H
T
L
G
Q
R
K
G
L
G
I
G
G
T
K
E
G
T
E
E
P
W
Y
V
V
D
K
D
V
E
N
N
I
L
V
V
A
Q
G
H
E
H
P
R
L
M
S
V
G
L
I
A
Q
Q
L
H
W
V
D
R
E
P
F
T
G
T
M
R
C
T
V
K
T
R
Y
R
Q
T
D
I
P
C
T
V
K
A
L
D
-
D
D
R
I
E
V
I
F
D
E
P
V
A
A
V
T
P
G
Q
S
A
V
F
Y
N
G
E
V
C
L
G
G
G
I
I
E
Q
-----------
4
PsiBlast_PDB
66.11
59%
-29
- C1 -
-
2DEU
1
MNMA_ECOLI
A:
[17-374]
----
A
K
-
K
V
I
V
G
M
S
G
G
V
D
S
S
V
S
A
W
L
L
Q
Q
Q
G
Y
Q
V
E
G
L
F
M
K
N
W
E
E
D
D
G
E
E
Y
C
T
A
A
A
D
L
A
D
A
Q
A
V
C
D
K
L
G
I
E
L
H
T
-
V
N
F
A
A
E
Y
W
D
N
V
F
E
L
F
L
A
E
Y
--
K
A
G
R
T
P
N
P
D
I
L
C
N
K
E
I
K
F
K
A
F
L
-
E
F
A
A
-
E
D
L
G
A
D
Y
I
A
T
G
H
Y
V
R
R
A
-
D
V
D
G
K
S
R
L
L
R
G
L
D
S
N
K
D
Q
S
Y
F
L
Y
T
L
S
H
E
Q
I
A
Q
S
L
F
P
V
G
--
E
L
-----
E
K
P
Q
V
R
K
I
A
E
D
L
G
L
V
T
A
K
---
K
K
D
S
T
G
I
C
F
I
G
E
R
----
K
F
R
---------
E
F
L
G
R
-----------
Y
--
L
P
A
Q
P
G
K
I
I
T
V
D
G
D
E
-----
I
G
E
H
Q
G
L
M
-
Y
H
T
L
G
Q
R
K
G
L
G
I
G
G
T
K
E
G
T
E
E
P
W
Y
V
V
D
K
D
V
E
N
N
I
L
V
V
A
Q
G
H
E
H
P
R
L
M
S
V
G
L
I
A
Q
Q
L
H
W
V
D
R
E
P
F
T
G
T
M
R
C
T
V
K
T
R
Y
R
Q
T
D
I
P
C
T
V
K
A
L
D
-
D
D
R
I
E
V
I
F
D
E
P
V
A
A
V
T
P
G
Q
S
A
V
F
Y
N
G
E
V
C
L
G
G
G
I
I
E
Q
-----------
3
PsiBlast_PDB
65.50
59%
-32
- C1 -
-
2DET
-
MNMA_ECOLI
A:
[16-374]
---
T
A
K
-
K
V
I
V
G
M
S
G
G
V
D
S
S
V
S
A
W
L
L
Q
Q
Q
G
Y
Q
V
E
G
L
F
M
K
N
W
E
E
D
D
G
E
E
Y
C
T
A
A
A
D
L
A
D
A
Q
A
V
C
D
K
L
G
I
E
L
H
T
-
V
N
F
A
A
E
Y
W
D
N
V
F
E
L
F
L
A
E
Y
--
K
A
G
R
T
P
N
P
D
I
L
C
N
K
E
I
K
F
K
A
F
L
-
E
F
A
A
-
E
D
L
G
A
D
Y
I
A
T
G
H
Y
V
R
R
A
-
D
V
D
G
K
S
R
L
L
R
G
L
D
S
N
K
D
Q
S
Y
F
L
Y
T
L
S
H
E
Q
I
A
Q
S
L
F
P
V
G
--
E
L
-----
E
K
P
Q
V
R
K
I
A
E
D
L
G
L
V
T
A
K
---
K
K
D
S
T
G
I
C
F
I
G
E
R
----
K
F
R
---------
E
F
L
G
R
-----------
Y
--
L
P
A
Q
P
G
K
I
I
T
V
D
G
D
E
-----
I
G
E
H
Q
G
L
M
-
Y
H
T
L
G
Q
R
K
G
L
G
I
G
G
T
K
E
G
T
E
E
P
W
Y
V
V
D
K
D
V
E
N
N
I
L
V
V
A
Q
G
H
E
H
P
R
L
M
S
V
G
L
I
A
Q
Q
L
H
W
V
D
R
E
P
F
T
G
T
M
R
C
T
V
K
T
R
Y
R
Q
T
D
I
P
C
T
V
K
A
L
D
-
D
D
R
I
E
V
I
F
D
E
P
V
A
A
V
T
P
G
Q
S
A
V
F
Y
N
G
E
V
C
L
G
G
G
I
I
E
Q
-----------
47
HHSearch
64.90
59%
-32
- C1 -
-
2DET
-
MNMA_ECOLI
A:
[16-378]
----
T
A
K
K
V
I
V
G
M
S
G
G
V
D
S
S
V
S
A
W
L
L
Q
Q
Q
G
Y
Q
V
E
G
L
F
M
K
N
W
E
E
D
D
G
E
E
Y
C
T
A
A
A
D
L
A
D
A
Q
A
V
C
D
K
L
G
I
E
L
H
T
-
V
N
F
A
A
E
Y
W
D
N
V
F
E
L
F
L
A
E
Y
--
K
A
G
R
T
P
N
P
D
I
L
C
N
K
E
I
K
F
K
A
F
L
E
F
A
A
E
-
D
-
L
G
A
D
Y
I
A
T
G
H
Y
V
R
R
A
D
V
-
D
G
K
S
R
L
L
R
G
L
D
S
N
K
D
Q
S
Y
F
L
Y
T
L
S
H
E
Q
I
A
Q
S
L
F
P
V
G
--
E
L
-----
E
K
P
Q
V
R
K
I
A
E
D
L
G
L
V
T
A
K
---
K
K
D
S
T
G
I
C
F
I
G
E
R
----
K
F
R
---------
E
F
L
G
R
-----------
Y
--
L
P
A
Q
P
G
K
I
I
T
V
D
G
D
E
-----
I
G
E
H
Q
G
L
M
-
Y
H
T
L
G
Q
R
K
G
L
G
I
G
G
T
K
E
G
T
E
E
P
W
Y
V
V
D
K
D
V
E
N
N
I
L
V
V
A
Q
G
H
E
H
P
R
L
M
S
V
G
L
I
A
Q
Q
L
H
W
V
D
R
E
P
F
T
G
T
M
R
C
T
V
K
T
R
Y
R
Q
T
D
I
P
C
T
V
K
-
A
L
D
D
D
R
I
E
V
I
F
D
E
P
V
A
A
V
T
P
G
Q
S
A
V
F
Y
N
G
E
V
C
L
G
G
G
I
I
E
Q
R
L
P
L
-------
46
HHSearch
64.59
59%
-36
- C1 -
-
2DER
-
MNMA_ECOLI
B:
[16-378]
----
T
A
K
K
V
I
V
G
M
S
G
G
V
D
S
S
V
S
A
W
L
L
Q
Q
Q
G
Y
Q
V
E
G
L
F
M
K
N
W
E
E
D
D
G
E
E
Y
C
T
A
A
A
D
L
A
D
A
Q
A
V
C
D
K
L
G
I
E
L
H
T
-
V
N
F
A
A
E
Y
W
D
N
V
F
E
L
F
L
A
E
Y
--
K
A
G
R
T
P
N
P
D
I
L
C
N
K
E
I
K
F
K
A
F
L
E
F
A
A
E
-
D
-
L
G
A
D
Y
I
A
T
G
H
Y
V
R
R
A
D
V
-
D
G
K
S
R
L
L
R
G
L
D
S
N
K
D
Q
S
Y
F
L
Y
T
L
S
H
E
Q
I
A
Q
S
L
F
P
V
G
--
E
L
-----
E
K
P
Q
V
R
K
I
A
E
D
L
G
L
V
T
---------
T
G
I
C
F
I
G
E
R
----
K
F
R
---------
E
F
L
G
R
-----------
Y
--
L
P
A
Q
P
G
K
I
I
T
V
D
G
D
E
-----
I
G
E
H
Q
G
L
M
-
Y
H
T
L
G
Q
R
K
G
L
G
I
G
G
T
K
E
G
T
E
E
P
W
Y
V
V
D
K
D
V
E
N
N
I
L
V
V
A
Q
G
H
E
H
P
R
L
M
S
V
G
L
I
A
Q
Q
L
H
W
V
D
R
E
P
F
T
G
T
M
R
C
T
V
K
T
R
Y
R
Q
T
D
I
P
C
T
V
K
-
A
L
D
D
D
R
I
E
V
I
F
D
E
P
V
A
A
V
T
P
G
Q
S
A
V
F
Y
N
G
E
V
C
L
G
G
G
I
I
E
Q
R
L
P
L
-------
2
PsiBlast_PDB
63.16
59%
-28
- C1 -
-
2DER
-
MNMA_ECOLI
A:
[17-374]
----
A
K
-
K
V
I
V
G
M
S
G
G
V
D
S
S
V
S
A
W
L
L
Q
Q
Q
G
Y
Q
V
E
G
L
F
M
K
N
W
E
E
D
D
G
E
E
Y
C
T
A
A
A
D
L
A
D
A
Q
A
V
C
D
K
L
G
I
E
L
H
T
-
V
N
F
A
A
E
Y
W
D
N
V
F
E
L
F
L
A
E
Y
--
K
A
G
R
T
P
N
P
D
I
L
C
N
K
E
I
K
F
K
A
F
L
-
E
F
A
A
-
E
D
L
G
A
D
Y
I
A
T
G
H
Y
V
R
R
A
-
D
V
D
G
K
S
R
L
L
R
G
L
D
S
N
K
D
Q
S
Y
F
L
Y
T
L
S
H
E
Q
I
A
Q
S
L
F
P
V
G
--
E
L
-----
E
K
P
Q
V
R
K
I
A
E
D
L
G
L
V
-----------------------
K
F
R
---------
E
F
L
G
R
-----------
Y
--
L
P
A
Q
P
G
K
I
I
T
V
D
G
D
E
-----
I
G
E
H
Q
G
L
M
-
Y
H
T
L
G
Q
R
K
G
L
G
I
G
G
T
K
E
G
T
E
E
P
W
Y
V
V
D
K
D
V
E
N
N
I
L
V
V
A
Q
G
H
E
H
P
R
L
M
S
V
G
L
I
A
Q
Q
L
H
W
V
D
R
E
P
F
T
G
T
M
R
C
T
V
K
T
R
Y
R
Q
T
D
I
P
C
T
V
K
A
L
D
-
D
D
R
I
E
V
I
F
D
E
P
V
A
A
V
T
P
G
Q
S
A
V
F
Y
N
G
E
V
C
L
G
G
G
I
I
E
Q
-----------
37
Fugue
62.63
57%
-26
- C1 -
-
2DER
-
MNMA_ECOLI
A:
[17-380]
-----
A
K
K
V
I
V
G
M
S
G
G
V
D
S
S
V
S
A
W
L
L
Q
Q
Q
G
Y
Q
V
E
G
L
F
M
K
N
W
E
E
D
D
G
E
E
Y
C
T
A
A
A
D
L
A
D
A
Q
A
V
C
D
K
L
G
I
E
L
H
T
-
V
N
F
A
A
E
Y
W
D
N
V
F
E
L
F
L
A
E
Y
--
K
A
G
R
T
P
N
P
D
I
L
C
N
K
E
I
K
F
K
A
F
L
-
E
F
A
A
E
D
-
L
G
A
D
Y
I
A
T
G
H
Y
V
R
R
A
D
V
-
D
G
K
S
R
L
L
R
G
L
D
S
N
K
D
Q
S
Y
F
L
Y
T
L
S
H
E
Q
I
A
Q
S
L
F
P
V
G
--
E
L
-----
E
K
P
Q
V
R
K
I
A
E
D
-------------------
L
G
L
V
----
K
F
R
---------
E
F
L
G
R
-----------
Y
--
L
P
A
Q
P
G
K
I
I
T
V
D
G
D
E
-----
I
G
E
H
Q
G
L
M
-
Y
H
T
L
G
Q
R
K
G
L
G
I
G
G
T
K
E
G
T
E
E
P
W
Y
V
V
D
K
D
V
E
N
N
I
L
V
V
A
Q
G
H
E
H
P
R
L
M
S
V
G
L
I
A
Q
Q
L
H
W
V
D
R
E
P
F
T
G
T
M
R
C
T
V
K
T
R
Y
R
Q
T
D
I
P
C
T
V
K
A
L
D
-
D
D
R
I
E
V
I
F
D
E
P
V
A
A
V
T
P
G
Q
S
A
V
F
Y
N
G
E
V
C
L
G
G
G
I
I
E
Q
R
L
P
L
P
V
-----
31
PsiBlast_CBE
38.51
39%
-202
- C1 -
-
5AUP
1
?
B:
[173-212]
------------------------
L
L
K
E
E
G
H
K
V
I
G
V
-
V
E
N
M
K
L
-------------
K
D
V
E
K
L
A
E
E
F
G
V
P
Y
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
58
HHSearch
38.06
20%
-107
- C1 -
-
5GHA
1
?
C:
[46-229]
----
P
G
E
R
V
L
V
A
V
S
G
G
K
D
S
L
A
L
W
D
V
L
S
R
L
G
Y
Q
A
V
G
L
H
I
E
L
G
I
G
E
------
Y
S
K
R
S
L
E
V
T
Q
A
F
A
R
E
R
G
L
E
L
L
V
-
V
D
L
K
E
A
Y
G
F
G
-
V
P
----
E
L
--
A
R
L
S
G
R
V
A
C
S
A
C
G
L
-
S
K
R
Y
I
I
N
-
Q
V
A
V
-
E
-
E
G
F
R
V
V
A
T
G
H
N
L
D
D
E
A
A
-
V
L
F
G
N
L
L
N
P
Q
------
G
P
V
L
P
--
E
K
P
G
L
A
A
R
V
K
P
F
Y
--
R
F
-----
S
E
R
E
V
L
S
Y
T
L
L
R
G
I
R
Y
L
H
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
37.95
50%
-231
- C1 -
-
1VL2
-
ASSY_THEMA
A:
[2-41]
-----
K
E
K
V
V
L
A
Y
S
G
G
L
D
T
S
V
I
L
K
W
L
C
E
K
G
F
D
V
I
A
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
PsiBlast_CBE
37.09
39%
-189
- C1 -
-
5AUO
1
?
B:
[173-212]
------------------------
L
L
K
E
E
G
H
K
V
I
G
V
-
V
E
N
M
K
L
-------------
K
D
V
E
K
L
A
E
E
F
G
V
P
Y
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
59
HHSearch
36.35
20%
-112
- C1 -
-
5GHA
2
?
B:
[46-221]
----
P
G
E
R
V
L
V
A
V
S
G
G
K
D
S
L
A
L
W
D
V
L
S
R
L
G
Y
Q
A
V
G
L
H
I
E
L
G
I
G
E
------
Y
S
K
R
S
L
E
V
T
Q
A
F
A
R
E
R
G
L
E
L
L
V
-
V
D
L
K
E
A
Y
G
F
G
-
V
P
----
E
L
--
A
R
L
S
G
R
V
A
C
S
A
C
G
L
-
S
K
R
Y
I
I
N
-
Q
V
A
V
-
E
-
E
G
F
R
V
V
A
T
G
H
N
L
D
D
E
A
A
-
V
L
F
G
N
L
L
N
P
Q
------
G
P
V
L
P
--
E
K
P
G
L
A
A
R
V
K
P
F
Y
--
R
F
-----
S
E
R
E
V
L
S
Y
T
L
L
R
G
I
R
Y
L
H
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
PsiBlast_CBE
35.52
39%
-169
- C1 -
-
5AUN
1
?
B:
[173-212]
------------------------
L
L
K
E
E
G
H
K
V
I
G
V
-
V
E
N
M
K
L
-------------
K
D
V
E
K
L
A
E
E
F
G
V
P
Y
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
35.47
48%
-210
- C1 -
-
2YWC
-
GUAA_THET8
A:
[209-271]
-----
K
D
R
V
L
L
A
V
S
G
G
V
D
S
S
T
L
A
L
L
L
A
K
A
G
V
D
H
L
A
V
F
V
D
H
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
34.21
55%
-227
- C1 -
-
2NZ2
-
ASSY_HUMAN
A:
[5-36]
-----
K
G
S
V
V
L
A
Y
S
G
G
L
D
T
S
C
I
L
V
W
L
K
E
Q
G
Y
D
V
I
A
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
33.91
48%
-208
- C1 -
-
2YWB
-
GUAA_THET8
A:
[209-272]
-----
K
D
R
V
L
L
A
V
S
G
G
V
D
S
S
T
L
A
L
L
L
A
K
A
G
V
D
H
L
A
V
F
V
D
H
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
33.35
28%
-137
- C1 -
-
3VRH
1
?
A:
[49-166]
-------
R
I
L
V
A
V
S
G
G
K
D
S
A
V
T
A
Y
V
L
K
K
L
G
Y
N
I
E
C
L
H
I
----
N
L
G
I
S
G
Y
S
E
K
S
E
E
Y
A
K
--
K
Q
C
K
L
I
G
A
P
L
H
I
-
V
R
I
K
E
-----
I
L
G
Y
G
I
G
E
V
--
K
T
R
R
P
P
C
S
Y
C
G
L
T
K
R
Y
I
M
N
K
F
----
A
Y
-
D
-
N
G
F
D
A
I
A
T
G
H
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
55
HHSearch
33.32
19%
-44
- C1 -
-
2NZ2
2
ASSY_HUMAN
A:
[5-268]
-----
K
G
S
V
V
L
A
Y
S
G
G
L
D
T
S
C
I
L
V
W
L
K
E
Q
G
Y
D
V
I
A
Y
L
A
N
I
G
Q
----------
K
E
D
F
E
E
A
R
K
K
A
L
K
L
G
A
K
K
V
F
I
E
D
V
S
R
E
F
V
E
E
F
I
W
P
A
I
Q
S
S
AL
Y
E
D
R
Y
L
L
G
T
S
L
A
-
R
P
C
I
A
R
K
Q
V
-
E
I
A
Q
-
R
-
E
G
A
K
Y
V
S
H
G
A
T
G
K
G
N
D
Q
-
V
R
F
E
L
S
C
Y
-------------
S
L
A
-
P
Q
-
I
K
V
I
A
P
W
R
MP
E
F
YNRFK-
R
N
D
L
M
E
Y
A
K
Q
H
G
I
P
I
P
V
TPK
N
P
W
S
M
D
E
N
L
M
H
I
S
Y
E
A
G
I
L
E
NPKNQAPPG
L
Y
T
K
T
QDPAKAPN
T
P
D
I
L
E
I
E
F
K
K
G
V
P
V
K
V
T
N
V
K
DGTTH
Q
T
S
L
E
L
F
M
Y
L
N
E
V
A
G
K
H
G
V
G
R
I
-----------------------------------------------------------------------------------------------------------------------------