@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : spr0154: (2017-12-16 )
MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYVQENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDYLVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEKQGSFTIPYYVLGQAWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNLQQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRIPITKQLFIQFVMDVFHLFEHLKADDMTDIVKTIHAIQSFDELVSYIKETLISFFGQYRMNENVVSVLEVIGRDYQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIEDICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70.--.......80........90........100.......110.......-120.......130.......140---...------------.....150.......160.......170.......180.......190--.......200......--.210.......220.......230.......240.......250.......260.......270.......280.......290.....--..300.......-------310.......320.-----......330.......340.......350---........360..-.....370.......380........390.......400-----.........410.......420........--
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
M
Y
K
V
L
L
VDD
E
Y
M
V
T
E
G
L
K
R
LIPFDKWD
M
E
V
V
A
TAS
H
A
D
E
A
L
E
Y
V
Q
ENP
V
D
V
I
I
SDVNMPDK
T
G
L
D
M
I
R
E
M
K
E
--ILP
D
A
A
Y
I
L
L
S
G
Y
Q
E
F
D
Y
V
K
R
AM
N
L
S
V
V
D
Y
L
VKP
V
D
K
V
E
L
G
N
L
L
E
K
I
-
A
G
Q
LGERGKKS
Q
T
L
S
Q
E
L
D
EA
G
----
F
V
S
------------YLGDKE
N
W
W
I
GLSKEKQG
S
F
TI
P
Y
Y
V
LG
Q
A
W
Q
I
F
ISDQPLD
G
L
V
VTPF--EA
P
Y
Q
E
H
F
E
R
WKLNAE--
K
T
L
F
Y
G
SVNLQ
Q
S
E
S
L
F
A
Y
Y
E
P
I
Y
R
V
I
IQG
N
L
N
Q
I
V
E
E
L
N
L
L
E
K
V
V
LENTPRIP
I
T
K
Q
L
F
I
Q
F
V
M
D
V
F
H
L
F
E
H
LKAD
D
M
T
D
I
V
K
T
I
H
A
I
--
Q
S
F
D
E
L
V
S
Y
I
K
E
-------
T
L
I
S
F
F
G
QYRMN
E
N
-----
V
V
S
V
L
E
V
I
G
R
D
Y
Q
K
EL
S
L
K
D
I
S
K
A
L
F
I
N
----
P
V
Y
L
G
Q
L
I
KRET
D
-
S
T
F
A
E
L
L
N
K
Q
R
I
K
A
A
Q
-
Q
L
L
LSTSD
S
I
E
D
I
C
Y
A
VGYS-------N
L
G
Y
F
Y
K
V
F
R
K
L
CGKS
P
K
A
Y
--
R
K
Q
V
E
T
IL--
60
Fugue
74.16
17%
-62
- C2 -
-
1NY5
3
?
A:
[1-384]
-
M
N
V
L
V
I
E
D
D
K
V
F
R
G
L
L
E
E
Y
L
S
M
K
G
I
---
K
V
E
S
A
E
R
G
K
E
A
Y
K
L
L
S
E
K
H
F
N
V
V
L
L
D
L
L
L
P
D
V
N
G
L
E
I
L
K
W
I
K
E
--
R
S
P
E
T
E
V
I
V
I
T
G
H
G
T
I
K
T
A
V
E
A
M
K
M
G
A
Y
D
F
L
T
K
P
C
M
L
E
E
I
E
L
T
I
N
K
A
-
I
E
H
R
K
L
R
K
E
N
E
L
L
R
R
E
K
D
L
K
E
E
----
E
Y
----------------------
V
F
E
S
P
K
M
K
E
I
L
E
K
I
K
K
I
S
C
A
E
C
P
V
L
I
T
G
E
S
G
V
G
--------------------------
K
E
V
V
A
R
L
I
H
K
L
S
D
R
S
--------
K
E
P
F
V
A
L
N
V
A
S
I
--
P
R
D
I
F
E
A
E
L
F
G
Y
E
------
K
G
A
F
T
G
A
V
S
S
K
E
G
F
F
E
L
--
A
D
G
G
T
L
F
L
D
E
I
G
E
L
S
L
E
A
Q
A
K
L
L
R
V
I
E
S
-------
G
K
F
Y
R
L
G
G
R
K
E
I
E
V
-----
N
V
R
I
L
A
A
T
N
R
N
I
K
E
L
V
K
E
G
K
F
R
E
D
L
Y
Y
R
L
G
V
I
E
I
E
I
P
P
L
R
E
R
K
E
D
I
I
P
L
A
N
H
F
L
K
K
F
S
R
K
Y
A
-
K
E
V
E
G
F
T
K
S
A
Q
E
L
L
L
S
Y
P
W
Y
G------
N
V
R
E
L
K
N
V
I
E
R
A
V
L
F
S
E
G
K
F
ID
R
G
E
L
S
C
L
V
--
61
Fugue
73.67
13%
-11
- C2 -
-
1W25
3
PLED_CAUCN
A:
[1-454]
S
A
R
I
L
V
V
D
D
I
E
A
N
V
R
L
L
E
A
K
L
T
A
E
Y
Y
---
E
V
S
T
A
M
D
G
P
T
A
L
A
M
A
A
R
D
L
P
D
I
I
L
L
D
V
M
M
P
G
M
D
G
F
T
V
C
R
K
L
K
D
DP
T
T
R
H
I
P
V
V
L
I
T
A
L
D
G
R
G
D
R
I
Q
G
L
E
S
G
A
S
D
F
L
T
K
P
I
D
D
V
M
L
F
A
R
V
R
S
L
-
T
R
F
K
L
V
I
D
E
L
R
Q
R
E
A
S
G
R
R
M
G
V
----
I
A
G
AAARLDG
L
G
G
R
V
L
I
V
D
D
N
E
R
Q
A
Q
R
V
A
A
E
L
G
V
E
H
R
P
V
I
E
S
D
P
E
K
A
K
I
S
A
G
G
P
V
D
L
V
I
V
N
A
A
AK
N
F
D
G
L
R
F
T
A
A
L
R
S
E
E
R
TR
Q
L
P
V
L
A
M
V
D
P
D
D
R
G
R
M
V
K
A
L
E
I
G
V
N
D
I
L
S
R
P
I
D
P
Q
E
L
S
A
R
V
K
T
Q
I
Q
R
K
R
Y
T
D
Y
L
R
N
N
L
D
H
S
L
---------
E
L
A
V
T
D
Q
L
T
G
L
H
N
R
R
Y
M
T
--
G
Q
L
D
S
L
V
K
R
A
T
L
G
G
D
P
V
S
A
L
L
I
D
I
D
F
F
K
K
I
N
D
T
FG
H
D
I
G
D
E
V
L
R
E
F
A
L
R
L
A
S
N
V
R
A
I
D
L
P
C
R
Y
G
G
E
----
E
F
V
V
--
I
M
P
D
T
A
L
-
A
D
A
L
R
I
A
E
R
I
R
M
H
V
S
G
S
P
F
T
V
A
H
G
R
E
M
L
N
V
T
I
S
I
G
V
S
A
T
A
G
EGD
T
P
E
A
L
L
K
R
A
D
E
G
V
Y
Q
A
K
A
S
G
--
R
N
A
V
V
G
K
A
AH
19
PsiBlast_PDB
70.88
28%
-135
- C2 -
-
3CZ5
-
?
A:
[7-139]
--
R
I
M
L
V
D
D
H
P
I
V
R
E
G
Y
R
R
L
I
E
-
R
R
P
G
Y
A
V
V
A
E
A
A
D
A
G
E
A
Y
R
L
Y
R
E
T
T
P
D
I
V
V
M
D
L
T
L
P
G
P
G
G
I
E
A
T
R
H
I
R
Q
--
W
D
G
A
A
R
I
L
I
F
T
M
H
Q
G
S
A
F
A
L
K
A
F
E
A
G
A
S
G
Y
V
T
K
S
S
D
P
A
E
L
V
Q
A
I
E
A
I
----
L
A
G
R
R
A
M
S
P
D
I
A
Q
E
I
A
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
70.45
31%
-162
- C2 -
-
1TMY
-
CHEY_THEMA
A:
[4-119]
--
R
V
L
I
V
D
D
A
A
F
M
R
M
M
L
K
D
I
I
--
T
K
A
G
Y
E
V
A
G
E
A
T
N
G
R
E
A
V
E
K
Y
K
E
L
K
P
D
I
V
T
M
D
I
T
M
P
E
M
N
G
I
D
A
I
K
E
I
M
K
--
I
D
P
N
A
K
I
I
V
C
S
A
M
G
Q
Q
A
M
V
I
E
A
I
K
A
G
A
K
D
F
I
V
K
P
F
Q
P
S
R
V
V
E
A
L
N
K
V
-
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
53
HHSearch
69.87
28%
-154
- C2 -
-
3DZD
-
?
B:
[1-118]
-
K
R
V
L
V
V
D
D
E
E
S
I
T
S
S
L
S
A
I
L
E
E
E
--
G
Y
H
-
P
D
T
A
K
T
L
R
E
A
E
K
K
I
K
E
L
F
F
P
V
I
V
L
D
V
W
M
P
D
G
D
G
V
N
F
I
D
F
I
K
E
--
N
S
P
D
S
V
V
I
V
I
T
G
H
G
S
V
D
T
A
V
K
A
I
K
K
G
A
Y
E
F
L
E
K
P
F
S
V
E
R
F
L
L
T
I
K
H
A
-
F
E
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
69.41
31%
-165
- C2 -
-
2TMY
-
CHEY_THEMA
A:
[4-119]
--
R
V
L
I
V
D
D
A
A
F
M
R
M
M
L
K
D
I
I
--
T
K
A
G
Y
E
V
A
G
E
A
T
N
G
R
E
A
V
E
K
Y
K
E
L
K
P
D
I
V
T
M
D
I
T
M
P
E
M
N
G
I
D
A
I
K
E
I
M
K
--
I
D
P
N
A
K
I
I
V
C
S
A
M
G
Q
Q
A
M
V
I
E
A
I
K
A
G
A
K
D
F
I
V
K
P
F
Q
P
S
R
V
V
E
A
L
N
K
V
-
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
68.43
31%
-140
- C2 -
-
4IGA
-
CHEY_THEMA
A:
[7-121]
--
R
V
L
I
V
D
D
A
A
F
M
R
M
M
L
K
D
I
I
T
--
K
A
G
Y
E
V
A
G
E
A
T
N
G
R
E
A
V
E
K
Y
K
E
L
K
P
D
I
V
T
M
D
I
T
M
P
E
M
N
G
I
D
A
I
K
E
I
M
K
--
I
D
P
N
A
K
I
I
V
C
S
A
M
G
Q
Q
A
M
V
I
E
A
I
K
A
G
A
K
D
F
I
V
K
P
F
Q
P
S
R
V
V
E
A
L
N
K
V
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
68.00
30%
-138
- C2 -
-
4LE2
-
DESR_BACSU
A:
[5-120]
M
I
S
I
F
I
A
E
D
Q
Q
M
L
L
G
A
L
G
S
L
L
N
L
E
D
-
D
M
E
V
V
G
K
G
T
T
G
Q
D
A
V
D
F
V
K
K
R
Q
P
D
V
C
I
M
D
I
E
M
P
G
K
T
G
L
E
A
A
E
E
L
K
D
--
T
--
G
C
K
I
I
I
L
T
T
F
A
R
P
G
Y
F
Q
R
A
I
K
A
G
V
K
G
Y
L
L
K
D
S
P
S
E
E
L
A
N
A
I
R
S
V
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
67.89
31%
-170
- C- -
-
1U0S
-
CHEY_THEMA
Y:
[4-119]
--
R
V
L
I
V
D
D
A
A
F
M
R
M
M
L
K
D
I
I
--
T
K
A
G
Y
E
V
A
G
E
A
T
N
G
R
E
A
V
E
K
Y
K
E
L
K
P
D
I
V
T
M
D
I
T
M
P
E
M
N
G
I
D
A
I
K
E
I
M
K
--
I
D
P
N
A
K
I
I
V
C
S
A
M
G
Q
Q
A
M
V
I
E
A
I
K
A
G
A
K
D
F
I
V
K
P
F
Q
P
S
R
V
V
E
A
L
N
K
V
-
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
67.82
30%
-133
- C2 -
-
4LE0
-
DESR_BACSU
A:
[5-120]
M
I
S
I
F
I
A
E
D
Q
Q
M
L
L
G
A
L
G
S
L
L
N
L
E
D
-
D
M
E
V
V
G
K
G
T
T
G
Q
D
A
V
D
F
V
K
K
R
Q
P
D
V
C
I
M
D
I
E
M
P
G
K
T
G
L
E
A
A
E
E
L
K
D
--
T
--
G
C
K
I
I
I
L
T
T
F
A
R
P
G
Y
F
Q
R
A
I
K
A
G
V
K
G
Y
L
L
K
D
S
P
S
E
E
L
A
N
A
I
R
S
V
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
67.23
31%
-134
- C2 -
-
4TMY
-
CHEY_THEMA
A:
[4-119]
--
R
V
L
I
V
D
D
A
A
F
M
R
M
M
L
K
D
I
I
--
T
K
A
G
Y
E
V
A
G
E
A
T
N
G
R
E
A
V
E
K
Y
K
E
L
K
P
D
I
V
T
M
D
I
T
M
P
E
M
N
G
I
D
A
I
K
E
I
M
K
--
I
D
P
N
A
K
I
I
V
C
S
A
M
G
Q
Q
A
M
V
I
E
A
I
K
A
G
A
K
D
F
I
V
K
P
F
Q
P
S
R
V
V
E
A
L
N
K
V
-
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
67.15
31%
-141
- C2 -
-
3TMY
-
CHEY_THEMA
A:
[4-119]
--
R
V
L
I
V
D
D
A
A
F
M
R
M
M
L
K
D
I
I
--
T
K
A
G
Y
E
V
A
G
E
A
T
N
G
R
E
A
V
E
K
Y
K
E
L
K
P
D
I
V
T
M
D
I
T
M
P
E
M
N
G
I
D
A
I
K
E
I
M
K
--
I
D
P
N
A
K
I
I
V
C
S
A
M
G
Q
Q
A
M
V
I
E
A
I
K
A
G
A
K
D
F
I
V
K
P
F
Q
P
S
R
V
V
E
A
L
N
K
V
-
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
66.75
30%
-143
- C2 -
-
4LDZ
2
DESR_BACSU
A:
[5-120]
M
I
S
I
F
I
A
E
D
Q
Q
M
L
L
G
A
L
G
S
L
L
N
L
E
D
-
D
M
E
V
V
G
K
G
T
T
G
Q
D
A
V
D
F
V
K
K
R
Q
P
D
V
C
I
M
D
I
E
M
P
G
K
T
G
L
E
A
A
E
E
L
K
D
--
T
--
G
C
K
I
I
I
L
T
T
F
A
R
P
G
Y
F
Q
R
A
I
K
A
G
V
K
G
Y
L
L
K
D
S
P
S
E
E
L
A
N
A
I
R
S
V
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
66.47
27%
-171
- C2 -
-
3CU5
-
?
A:
[4-119]
--
R
I
L
I
V
D
D
E
K
L
T
R
D
G
L
I
A
N
I
N
W
K
A
L
S
F
D
Q
I
D
Q
A
D
D
G
I
N
A
I
Q
I
A
L
K
H
P
P
N
V
L
L
T
D
V
R
M
P
R
M
D
G
I
E
L
V
D
N
I
L
K
--
L
Y
P
D
C
S
V
I
F
M
S
G
Y
S
D
K
E
Y
L
------
R
A
I
R
Y
V
E
K
P
I
D
P
S
E
I
M
D
A
L
K
Q
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
65.96
30%
-133
- C2 -
-
5IUK
-
DESR_BACSU
C:
[5-120]
M
I
S
I
F
I
A
E
D
Q
Q
M
L
L
G
A
L
G
S
L
L
N
L
E
D
-
D
M
E
V
V
G
K
G
T
T
G
Q
D
A
V
D
F
V
K
K
R
Q
P
D
V
C
I
M
D
I
E
M
P
G
K
T
G
L
E
A
A
E
E
L
K
D
--
T
--
G
C
K
I
I
I
L
T
T
F
A
R
P
G
Y
F
Q
R
A
I
K
A
G
V
K
G
Y
L
L
K
D
S
P
S
E
E
L
A
N
A
I
R
S
V
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
65.86
30%
-130
- C2 -
-
5IUL
-
DESR_BACSU
C:
[5-120]
M
I
S
I
F
I
A
E
D
Q
Q
M
L
L
G
A
L
G
S
L
L
N
L
E
D
-
D
M
E
V
V
G
K
G
T
T
G
Q
D
A
V
D
F
V
K
K
R
Q
P
D
V
C
I
M
D
I
E
M
P
G
K
T
G
L
E
A
A
E
E
L
K
D
--
T
--
G
C
K
I
I
I
L
T
T
F
A
R
P
G
Y
F
Q
R
A
I
K
A
G
V
K
G
Y
L
L
K
D
S
P
S
E
E
L
A
N
A
I
R
S
V
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
41
HHSearch
65.85
35%
-131
- C1 -
-
3OOU
1
?
A:
[4-107]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
P
I
-----
I
Q
N
V
L
S
Y
I
T
E
H
F
S
E
G
M
S
L
K
T
L
G
N
D
F
H
I
N
----
A
V
Y
L
G
Q
L
F
Q
K
E
M
G
-
E
H
F
T
D
Y
L
N
R
Y
R
V
N
Y
A
K
-
E
E
L
L
Q
T
K
D
N
L
T
I
I
A
G
K
S
G
Y
T
-------
D
M
A
Y
F
Y
R
Q
F
K
K
H
T
G
E
T
P
N
R
Y
--
R
K
I
H
------
12
PsiBlast_PDB
65.50
29%
-118
- C2 -
-
3C3W
-
DEVR_MYCTU
A:
[1-163]
M
V
K
V
F
L
V
D
D
H
E
V
V
R
R
G
L
V
D
L
L
G
A
D
P
-
E
L
D
V
V
G
E
A
G
S
V
A
E
A
M
A
R
V
P
A
A
R
P
D
V
A
V
L
D
V
R
L
P
D
G
N
G
I
E
L
C
R
D
L
L
S
--
R
M
P
D
L
R
C
L
I
L
T
S
Y
T
S
D
E
A
M
L
D
A
I
L
A
G
A
S
G
Y
V
V
K
D
I
K
G
M
E
L
A
R
A
V
K
D
V
G
A
G
R
S
L
L
D
N
R
A
A
A
A
L
M
A
K
L
R
G
A
A
E
K
Q
D
P
L
S
------------
G
L
T
D
Q
E
R
T
L
L
G
L
L
S
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
65.49
30%
-130
- C2 -
-
5IUN
-
DESR_BACSU
C:
[5-120]
M
I
S
I
F
I
A
E
D
Q
Q
M
L
L
G
A
L
G
S
L
L
N
L
E
D
-
D
M
E
V
V
G
K
G
T
T
G
Q
D
A
V
D
F
V
K
K
R
Q
P
D
V
C
I
M
D
I
E
M
P
G
K
T
G
L
E
A
A
E
E
L
K
D
--
T
--
G
C
K
I
I
I
L
T
T
F
A
R
P
G
Y
F
Q
R
A
I
K
A
G
V
K
G
Y
L
L
K
D
S
P
S
E
E
L
A
N
A
I
R
S
V
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
65.39
30%
-131
- C2 -
-
5IUJ
-
DESR_BACSU
C:
[5-120]
M
I
S
I
F
I
A
E
D
Q
Q
M
L
L
G
A
L
G
S
L
L
N
L
E
D
-
D
M
E
V
V
G
K
G
T
T
G
Q
D
A
V
D
F
V
K
K
R
Q
P
D
V
C
I
M
D
I
E
M
P
G
K
T
G
L
E
A
A
E
E
L
K
D
--
T
--
G
C
K
I
I
I
L
T
T
F
A
R
P
G
Y
F
Q
R
A
I
K
A
G
V
K
G
Y
L
L
K
D
S
P
S
E
E
L
A
N
A
I
R
S
V
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------