@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : spr0162: (2017-12-16 )
MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTENVNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEERGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGLCCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYGNFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKAMKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLRKYHIGAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRMGHILNMEEK
Atome Classification :
(31 SA)
.........10........20........30........40........50........60........70........80........90-.-.-.-..-....100.......110.......120.......130.......140.......150.......160...-.--.--..-----------170----------.........180.......190.......200.......210.......220.......230.......240.-......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
M
E
Y
R
K
I
Q
E
A
L
E
A
L
QKG
R
L
V
L
V
IDDKDRENEG
D
L
I
CSAQAATTEN
V
N
F
M
A
T
YAK
G
L
I
CMP
M
S
E
S
L
A
N
Q
L
M
LSPMVENNTDN
H
K
T
A
F
T
V
S
I
D--Y-K-E-TT-TGISAEERG
L
T
A
R
M
C
VAEDI
T
P
S
D
FRRPGHM
F
P
L
I
AKKG
G
V
LERNGH
T
E
A
T
V
D
L
L
K
L
A
G
L
K
E
C
G
L
C
C
E
I
M-N--H--DG-----------
K
------------
M
M
R
T
D
D
L
I
Q
F
S
KKHNI
P
L
I
T
I
K
E
L
Q
E
Y
R
K
V
Y
D
Q
L
V
E
R
V
S
TVNMPTRYGNF
K
A
I
S
Y
I
D
KLNGE
H
H
L
A
L
I
M
GNIE-
D
E
A
N
V
L
C
R
V
H
S
E
CL
T
G
D
V
L
G
S
L
R
C
D
C
G
Q
Q
F
D
K
A
M
K
M
I
V
ENG
S
G
V
L
L
Y
L
RQEGRGI
G
L
I
N
K
L
K
A
Y
H
LQDQGMDTLDA
N
L
A
LGFEGD
L
R
K
Y
H
I
G
A
Q
M
L
K
D
LG
L
Q
S
L
H
LLTNN
P
D
K
V
E
Q
L
E
K
YG
I
T
I
S
S
R
I
S
I
E
I
EANPY
D
S
F
Y
L
ETKKNRMGHILNMEEK
2
PsiBlast_PDB
81.74
48%
-66
- C4 -
-
4I14
-
RIBBA_MYCTA
A:
[6-383]
----
S
V
E
R
A
V
A
D
I
A
A
G
K
A
V
I
V
I
D
D
E
D
R
E
N
E
G
D
L
I
F
A
A
E
K
A
T
P
E
M
V
A
F
M
V
R
Y
T
S
G
Y
L
C
V
P
L
D
G
A
I
C
D
R
L
G
L
L
P
M
Y
---------
A
Y
T
V
T
V
D
--
A
-
R
-
N
-
G
I
G
T
G
I
S
A
S
D
R
A
T
T
M
R
L
L
A
D
P
T
S
V
A
D
D
F
T
R
P
G
H
V
V
P
L
R
A
K
D
G
G
V
L
R
R
P
G
H
T
E
A
A
V
D
L
A
R
M
A
G
L
Q
P
A
G
A
I
C
E
I
V
-
S
--
Q
KD
E
G
-----------
S
------------
M
A
H
T
D
E
L
R
V
F
A
D
E
H
G
L
A
L
I
T
I
A
D
L
I
E
W
R
R
K
H
E
K
H
I
E
R
V
A
E
A
R
I
P
T
R
H
G
E
F
R
A
I
G
Y
T
S
I
Y
E
D
V
E
H
V
A
L
V
R
G
E
I
A
G
D
G
D
D
V
L
V
R
V
H
S
E
C
L
T
G
D
V
F
G
S
R
R
C
D
C
G
P
Q
L
D
A
A
L
A
M
V
A
R
E
G
R
G
V
V
L
Y
M
R
---------------------------------------
Y
G
I
G
A
Q
I
L
V
D
L
G
V
R
S
M
R
L
L
T
N
N
P
------
D
G
Y
G
L
H
I
I
E
R
V
P
L
P
---------------------------
1
PsiBlast_PDB
79.53
100%
-124
- C4 -
-
4FFJ
5
?
A:
[1-204]
M
E
Y
R
K
I
Q
E
A
L
E
A
L
Q
K
G
R
L
V
L
V
I
D
D
K
D
--
N
E
G
D
L
I
C
S
A
Q
A
A
T
T
E
N
V
N
F
M
A
T
Y
A
K
G
L
I
C
M
P
M
S
E
S
L
A
N
Q
L
M
L
S
P
M
V
E
-------
T
A
F
T
V
S
I
D
--
Y
-
K
-
E
-
T
T
-
T
G
I
S
A
E
E
R
G
L
T
A
R
M
C
V
A
E
D
I
T
P
S
D
F
R
R
P
G
H
M
F
P
L
I
A
K
K
G
G
V
L
E
R
N
G
H
T
E
A
T
V
D
L
L
K
L
A
G
L
K
E
C
G
L
C
C
E
I
M
-
N
--
H
--
D
G
-----------
K
------------
M
M
R
T
D
D
L
I
Q
F
S
K
K
H
N
I
P
L
I
T
I
K
E
L
Q
E
Y
R
K
V
Y
D
Q
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
82
HHSearch
79.50
100%
-124
- C4 -
-
4FFJ
5
?
A:
[1-204]
M
E
Y
R
K
I
Q
E
A
L
E
A
L
Q
K
G
R
L
V
L
V
I
D
D
K
D
--
N
E
G
D
L
I
C
S
A
Q
A
A
T
T
E
N
V
N
F
M
A
T
Y
A
K
G
L
I
C
M
P
M
S
E
S
L
A
N
Q
L
M
L
S
P
M
V
E
-------
T
A
F
T
V
S
I
D
--
Y
-
K
-
E
-
T
T
-
T
G
I
S
A
E
E
R
G
L
T
A
R
M
C
V
A
E
D
I
T
P
S
D
F
R
R
P
G
H
M
F
P
L
I
A
K
K
G
G
V
L
E
R
N
G
H
T
E
A
T
V
D
L
L
K
L
A
G
L
K
E
C
G
L
C
C
E
I
M
-
N
--
H
--
D
G
-----------
K
------------
M
M
R
T
D
D
L
I
Q
F
S
K
K
H
N
I
P
L
I
T
I
K
E
L
Q
E
Y
R
K
V
Y
D
Q
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
PsiBlast_CBE
66.41
50%
-77
- C4 -
-
1TKU
1
RIB3_CANAL
B:
[5-201]
--
F
T
P
I
E
E
A
L
E
A
Y
K
N
G
E
F
L
I
V
M
D
D
E
D
R
E
N
E
G
D
L
I
M
A
A
E
L
I
T
Q
E
K
M
A
F
L
V
R
Y
S
S
G
Y
V
C
V
P
L
S
E
E
R
A
N
Q
L
E
L
P
P
M
L
A
------
G
T
A
Y
T
I
T
C
D
--
F
-
A
-
E
G
T
T
-
T
G
I
S
A
H
D
R
A
L
T
T
R
S
L
A
N
P
N
S
K
P
Q
D
F
I
K
P
G
H
I
L
P
L
R
A
V
P
G
L
L
K
K
R
R
G
H
T
E
A
A
V
Q
L
S
T
L
A
G
L
Q
P
A
G
V
I
C
E
L
V
R
D
--
E
--
D
G
-----------
L
------------
M
M
R
L
D
D
C
I
Q
F
G
K
K
H
G
I
K
I
I
N
I
N
Q
L
V
E
Y
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
66.37
50%
-79
- C4 -
-
2RIS
-
RIB3_CANAL
A:
[5-201]
--
F
T
P
I
E
E
A
L
E
A
Y
K
N
G
E
F
L
I
V
M
D
D
E
D
R
E
N
E
G
D
L
I
M
A
A
E
L
I
T
Q
E
K
M
A
F
L
V
R
Y
S
S
G
Y
V
C
V
P
L
S
E
E
R
A
N
Q
L
E
L
P
P
M
L
A
------
G
T
A
Y
T
I
T
C
D
--
F
-
A
-
E
G
T
T
-
T
G
I
S
A
H
D
R
A
L
T
T
R
S
L
A
N
P
N
S
K
P
Q
D
F
I
K
P
G
H
I
L
P
L
R
A
V
P
G
L
L
K
K
R
R
G
H
T
E
A
A
V
Q
L
S
T
L
A
G
L
Q
P
A
G
V
I
C
E
L
V
R
D
--
E
--
D
G
-----------
L
------------
M
M
R
L
D
D
C
I
Q
F
G
K
K
H
G
I
K
I
I
N
I
N
Q
L
V
E
Y
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
83
HHSearch
66.36
49%
-76
- C4 -
-
2RIS
-
RIB3_CANAL
A:
[4-203]
-
I
F
T
P
I
E
E
A
L
E
A
Y
K
N
G
E
F
L
I
V
M
D
D
E
D
R
E
N
E
G
D
L
I
M
A
A
E
L
I
T
Q
E
K
M
A
F
L
V
R
Y
S
S
G
Y
V
C
V
P
L
S
E
E
R
A
N
Q
L
E
L
P
P
M
L
A
------
G
T
A
Y
T
I
T
C
D
--
F
A
E
-
G
-
T
T
-
T
G
I
S
A
H
D
R
A
L
T
T
R
S
L
A
N
P
N
S
K
P
Q
D
F
I
K
P
G
H
I
L
P
L
R
A
V
P
G
L
L
K
K
R
R
G
H
T
E
A
A
V
Q
L
S
T
L
A
G
L
Q
P
A
G
V
I
C
E
L
V
-
R
--
D
E-
D
G
-----------
L
------------
M
M
R
L
D
D
C
I
Q
F
G
K
K
H
G
I
K
I
I
N
I
N
Q
L
V
E
Y
I
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
66.25
50%
-75
- C4 -
-
2RIU
1
RIB3_CANAL
A:
[5-201]
--
F
T
P
I
E
E
A
L
E
A
Y
K
N
G
E
F
L
I
V
M
D
D
E
D
R
E
N
E
G
D
L
I
M
A
A
E
L
I
T
Q
E
K
M
A
F
L
V
R
Y
S
S
G
Y
V
C
V
P
L
S
E
E
R
A
N
Q
L
E
L
P
P
M
L
A
------
G
T
A
Y
T
I
T
C
D
--
F
-
A
-
E
G
T
T
-
T
G
I
S
A
H
D
R
A
L
T
T
R
S
L
A
N
P
N
S
K
P
Q
D
F
I
K
P
G
H
I
L
P
L
R
A
V
P
G
L
L
K
K
R
R
G
H
T
E
A
A
V
Q
L
S
T
L
A
G
L
Q
P
A
G
V
I
C
E
L
V
R
D
--
E
--
D
G
-----------
L
------------
M
M
R
L
D
D
C
I
Q
F
G
K
K
H
G
I
K
I
I
N
I
N
Q
L
V
E
Y
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
84
HHSearch
66.24
49%
-75
- C4 -
-
1TKU
1
RIB3_CANAL
B:
[4-203]
-
I
F
T
P
I
E
E
A
L
E
A
Y
K
N
G
E
F
L
I
V
M
D
D
E
D
R
E
N
E
G
D
L
I
M
A
A
E
L
I
T
Q
E
K
M
A
F
L
V
R
Y
S
S
G
Y
V
C
V
P
L
S
E
E
R
A
N
Q
L
E
L
P
P
M
L
A
------
G
T
A
Y
T
I
T
C
D
--
F
A
E
-
G
-
T
T
-
T
G
I
S
A
H
D
R
A
L
T
T
R
S
L
A
N
P
N
S
K
P
Q
D
F
I
K
P
G
H
I
L
P
L
R
A
V
P
G
L
L
K
K
R
R
G
H
T
E
A
A
V
Q
L
S
T
L
A
G
L
Q
P
A
G
V
I
C
E
L
V
-
R
--
D
E-
D
G
-----------
L
------------
M
M
R
L
D
D
C
I
Q
F
G
K
K
H
G
I
K
I
I
N
I
N
Q
L
V
E
Y
I
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
66.13
50%
-80
- C4 -
-
1TKS
-
RIB3_CANAL
A:
[5-201]
--
F
T
P
I
E
E
A
L
E
A
Y
K
N
G
E
F
L
I
V
M
D
D
E
D
R
E
N
E
G
D
L
I
M
A
A
E
L
I
T
Q
E
K
M
A
F
L
V
R
Y
S
S
G
Y
V
C
V
P
L
S
E
E
R
A
N
Q
L
E
L
P
P
M
L
A
------
G
T
A
Y
T
I
T
C
D
--
F
-
A
-
E
G
T
T
-
T
G
I
S
A
H
D
R
A
L
T
T
R
S
L
A
N
P
N
S
K
P
Q
D
F
I
K
P
G
H
I
L
P
L
R
A
V
P
G
L
L
K
K
R
R
G
H
T
E
A
A
V
Q
L
S
T
L
A
G
L
Q
P
A
G
V
I
C
E
L
V
R
D
--
E
--
D
G
-----------
L
------------
M
M
R
L
D
D
C
I
Q
F
G
K
K
H
G
I
K
I
I
N
I
N
Q
L
V
E
Y
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
66.04
50%
-75
- C4 -
-
1TKU
1
RIB3_CANAL
A:
[5-201]
--
F
T
P
I
E
E
A
L
E
A
Y
K
N
G
E
F
L
I
V
M
D
D
E
D
R
E
N
E
G
D
L
I
M
A
A
E
L
I
T
Q
E
K
M
A
F
L
V
R
Y
S
S
G
Y
V
C
V
P
L
S
E
E
R
A
N
Q
L
E
L
P
P
M
L
A
------
G
T
A
Y
T
I
T
C
D
--
F
-
A
-
E
G
T
T
-
T
G
I
S
A
H
D
R
A
L
T
T
R
S
L
A
N
P
N
S
K
P
Q
D
F
I
K
P
G
H
I
L
P
L
R
A
V
P
G
L
L
K
K
R
R
G
H
T
E
A
A
V
Q
L
S
T
L
A
G
L
Q
P
A
G
V
I
C
E
L
V
R
D
--
E
--
D
G
-----------
L
------------
M
M
R
L
D
D
C
I
Q
F
G
K
K
H
G
I
K
I
I
N
I
N
Q
L
V
E
Y
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
65.70
45%
-84
- C4 -
-
3LS6
1
RIBB_SALTY
A:
[13-211]
--
F
E
R
V
E
L
A
L
D
A
L
R
E
G
R
G
V
M
V
L
D
D
E
D
R
E
N
E
G
D
M
I
F
P
A
E
T
M
T
V
E
Q
M
A
L
T
I
R
H
G
S
G
I
V
C
L
C
I
T
E
D
R
R
K
Q
L
D
L
P
M
M
V
E
N
N
T
S
A
Y
G
T
G
F
T
V
T
I
E
--
A
-
A
-
E
G
V
T
-
T
G
V
S
A
A
D
R
V
T
T
V
R
A
A
I
K
D
G
A
K
P
S
D
L
N
R
P
G
H
V
F
P
L
R
A
Q
A
G
G
V
L
T
R
G
G
H
T
E
A
T
I
D
L
M
T
L
A
G
F
K
P
A
G
V
L
C
E
L
T
-
N
--
D
--
D
G
-----------
T
------------
M
A
R
A
P
E
C
I
A
F
A
G
Q
H
N
M
A
V
V
T
I
E
D
L
V
A
Y
R
Q
A
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
PsiBlast_CBE
65.31
45%
-87
- C4 -
-
3LQU
1
RIBB_SALTY
B:
[13-212]
--
F
E
R
V
E
L
A
L
D
A
L
R
E
G
R
G
V
M
V
L
D
----
E
N
E
G
D
M
I
F
P
A
E
T
M
T
V
E
Q
M
A
L
T
I
R
H
G
S
G
I
V
C
L
C
I
T
E
D
R
R
K
Q
L
D
L
P
M
M
V
E
N
N
T
S
A
Y
G
T
G
F
T
V
T
I
E
--
A
-
A
-
E
G
V
T
-
T
G
V
S
A
A
D
R
V
T
T
V
R
A
A
I
K
D
G
A
K
P
S
D
L
N
R
P
G
H
V
F
P
L
R
A
Q
A
G
G
V
L
T
R
G
G
H
T
E
A
T
I
D
L
M
T
L
A
G
F
K
P
A
G
V
L
C
E
L
T
-
N
--
D
--
D
G
-----------
T
------------
M
A
R
A
P
E
C
I
A
F
A
G
Q
H
N
M
A
V
V
T
I
E
D
L
V
A
Y
R
Q
A
H
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
85
HHSearch
64.81
45%
-76
- C4 -
-
4P6P
2
RIBB_VIBCH
B:
[32-233]
-
P
I
T
R
V
E
N
A
L
Q
A
L
R
E
G
R
G
V
L
L
L
D
D
E
D
R
E
N
E
G
D
I
I
Y
A
V
E
S
L
T
T
A
Q
M
A
L
M
I
R
E
C
S
G
I
V
C
L
C
L
T
E
A
Q
A
D
R
L
A
L
P
P
M
V
V
N
N
N
S
A
N
Q
T
A
F
T
V
S
I
E
--
A
K
H
-
G
-
V
T
-
T
G
V
S
A
Q
D
R
V
T
T
I
K
T
A
A
N
P
Q
A
K
P
E
D
L
A
R
P
G
H
V
F
P
L
R
A
R
A
G
G
V
L
A
R
R
G
H
T
E
G
T
V
D
L
M
Q
M
A
G
L
Q
P
A
G
V
L
C
E
L
T
-
N
--
P
--
D
G
-----------
S
------------
M
A
K
T
P
E
I
I
E
F
G
K
L
H
N
M
P
V
L
T
I
E
D
M
V
Q
Y
R
I
Q
F
D
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
64.81
46%
-75
- C4 -
-
4P6C
2
RIBB_VIBCH
A:
[36-234]
----
R
V
E
N
A
L
Q
A
L
R
E
G
R
G
V
L
L
L
D
D
E
D
R
E
N
E
G
D
I
I
Y
A
V
E
S
L
T
T
A
Q
M
A
L
M
I
R
E
C
S
G
I
V
C
L
C
L
T
E
A
Q
A
D
R
L
A
L
P
P
M
V
V
N
N
N
S
A
N
Q
T
A
F
T
V
S
I
E
--
A
-
K
-
H
G
V
T
-
T
G
V
S
A
Q
D
R
V
T
T
I
K
T
A
A
N
P
Q
A
K
P
E
D
L
A
R
P
G
H
V
F
P
L
R
A
R
A
G
G
V
L
A
R
R
G
H
T
E
G
T
V
D
L
M
Q
M
A
G
L
Q
P
A
G
V
L
C
E
L
T
-
N
--
P
--
D
G
-----------
S
------------
M
A
K
T
P
E
I
I
E
F
G
K
L
H
N
M
P
V
L
T
I
E
D
M
V
Q
Y
R
I
Q
F
D
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
PsiBlast_CBE
64.66
46%
-76
- C4 -
-
4P8E
7
RIBB_VIBCH
B:
[35-233]
----
R
V
E
N
A
L
Q
A
L
R
E
G
R
G
V
L
L
L
D
D
E
D
R
E
N
E
G
D
I
I
Y
A
V
E
S
L
T
T
A
Q
M
A
L
M
I
R
E
C
S
G
I
V
C
L
C
L
T
E
A
Q
A
D
R
L
A
L
P
P
M
V
V
N
N
N
S
A
N
Q
T
A
F
T
V
S
I
E
--
A
-
K
-
H
G
V
T
-
T
G
V
S
A
Q
D
R
V
T
T
I
K
T
A
A
N
P
Q
A
K
P
E
D
L
A
R
P
G
H
V
F
P
L
R
A
R
A
G
G
V
L
A
R
R
G
H
T
E
G
T
V
D
L
M
Q
M
A
G
L
Q
P
A
G
V
L
C
E
L
T
-
N
--
P
--
D
G
-----------
S
------------
M
A
K
T
P
E
I
I
E
F
G
K
L
H
N
M
P
V
L
T
I
E
D
M
V
Q
Y
R
I
Q
F
D
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
PsiBlast_CBE
64.64
46%
-76
- C4 -
-
4P6P
2
RIBB_VIBCH
B:
[35-233]
----
R
V
E
N
A
L
Q
A
L
R
E
G
R
G
V
L
L
L
D
D
E
D
R
E
N
E
G
D
I
I
Y
A
V
E
S
L
T
T
A
Q
M
A
L
M
I
R
E
C
S
G
I
V
C
L
C
L
T
E
A
Q
A
D
R
L
A
L
P
P
M
V
V
N
N
N
S
A
N
Q
T
A
F
T
V
S
I
E
--
A
-
K
-
H
G
V
T
-
T
G
V
S
A
Q
D
R
V
T
T
I
K
T
A
A
N
P
Q
A
K
P
E
D
L
A
R
P
G
H
V
F
P
L
R
A
R
A
G
G
V
L
A
R
R
G
H
T
E
G
T
V
D
L
M
Q
M
A
G
L
Q
P
A
G
V
L
C
E
L
T
-
N
--
P
--
D
G
-----------
S
------------
M
A
K
T
P
E
I
I
E
F
G
K
L
H
N
M
P
V
L
T
I
E
D
M
V
Q
Y
R
I
Q
F
D
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
64.56
46%
-75
- C4 -
-
4P77
3
RIBB_VIBCH
A:
[35-233]
----
R
V
E
N
A
L
Q
A
L
R
E
G
R
G
V
L
L
L
D
D
E
D
R
E
N
E
G
D
I
I
Y
A
V
E
S
L
T
T
A
Q
M
A
L
M
I
R
E
C
S
G
I
V
C
L
C
L
T
E
A
Q
A
D
R
L
A
L
P
P
M
V
V
N
N
N
--
N
Q
T
A
F
T
V
S
I
E
--
A
-
K
-
H
G
V
T
-
T
G
V
S
A
Q
D
R
V
T
T
I
K
T
A
A
N
P
Q
A
K
P
E
D
L
A
R
P
G
H
V
F
P
L
R
A
R
A
G
G
V
L
A
R
R
G
H
T
E
G
T
V
D
L
M
Q
M
A
G
L
Q
P
A
G
V
L
C
E
L
T
-
N
--
P
--
D
G
-----------
S
------------
M
A
K
T
P
E
I
I
E
F
G
K
L
H
N
M
P
V
L
T
I
E
D
M
V
Q
Y
R
I
Q
F
D
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
64.19
47%
-89
- C4 -
-
1G57
-
RIBB_ECOLI
A:
[13-213]
--
F
E
R
V
E
N
A
L
A
A
L
R
E
G
R
G
V
M
V
L
D
----
E
N
E
G
D
M
I
F
P
A
E
T
M
T
V
E
Q
M
A
L
T
I
R
H
G
S
G
I
V
C
L
C
I
T
E
D
R
R
K
Q
L
D
L
P
M
M
V
E
N
N
T
S
A
Y
G
T
G
F
T
V
T
I
E
--
A
-
A
-
E
G
V
T
-
T
G
V
S
A
A
D
R
I
T
T
V
R
A
A
I
A
D
G
A
K
P
S
D
L
N
R
P
G
H
V
F
P
L
R
A
Q
A
G
G
V
L
T
R
G
G
H
T
E
A
T
I
D
L
M
T
L
A
G
F
K
P
A
G
V
L
C
E
L
T
-
N
--
D
--
D
G
-----------
T
------------
M
A
R
A
P
E
C
I
E
F
A
N
K
H
N
M
A
L
V
T
I
E
D
L
V
A
Y
R
Q
A
H
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
93
HHSearch
64.17
47%
-86
- C4 -
-
1G57
-
RIBB_ECOLI
A:
[12-213]
-
P
F
E
R
V
E
N
A
L
A
A
L
R
E
G
R
G
V
M
V
L
D
----
E
N
E
G
D
M
I
F
P
A
E
T
M
T
V
E
Q
M
A
L
T
I
R
H
G
S
G
I
V
C
L
C
I
T
E
D
R
R
K
Q
L
D
L
P
M
M
V
E
N
N
T
S
A
Y
G
T
G
F
T
V
T
I
E
--
A
A
E
-
G
-
V
T
-
T
G
V
S
A
A
D
R
I
T
T
V
R
A
A
I
A
D
G
A
K
P
S
D
L
N
R
P
G
H
V
F
P
L
R
A
Q
A
G
G
V
L
T
R
G
G
H
T
E
A
T
I
D
L
M
T
L
A
G
F
K
P
A
G
V
L
C
E
L
T
-
N
--
D
--
D
G
-----------
T
------------
M
A
R
A
P
E
C
I
E
F
A
N
K
H
N
M
A
L
V
T
I
E
D
L
V
A
Y
R
Q
A
H
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
64.14
46%
-79
- C4 -
-
4P8E
5
RIBB_VIBCH
A:
[35-233]
----
R
V
E
N
A
L
Q
A
L
R
E
G
R
G
V
L
L
L
D
D
E
D
R
E
N
E
G
D
I
I
Y
A
V
E
S
L
T
T
A
Q
M
A
L
M
I
R
E
C
S
G
I
V
C
L
C
L
T
E
A
Q
A
D
R
L
A
L
P
P
M
V
V
N
N
N
S
A
N
Q
T
A
F
T
V
S
I
E
--
A
-
K
-
H
G
V
T
-
T
G
V
S
A
Q
D
R
V
T
T
I
K
T
A
A
N
P
Q
A
K
P
E
D
L
A
R
P
G
H
V
F
P
L
R
A
R
A
G
G
V
L
A
R
R
G
H
T
E
G
T
V
D
L
M
Q
M
A
G
L
Q
P
A
G
V
L
C
E
L
T
-
N
--
P
--
D
G
-----------
S
------------
M
A
K
T
P
E
I
I
E
F
G
K
L
H
N
M
P
V
L
T
I
E
D
M
V
Q
Y
R
I
Q
F
D
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
64.05
45%
-86
- C4 -
-
3LQU
1
RIBB_SALTY
A:
[13-212]
--
F
E
R
V
E
L
A
L
D
A
L
R
E
G
R
G
V
M
V
L
D
D
E
D
R
E
N
E
G
D
M
I
F
P
A
E
T
M
T
V
E
Q
M
A
L
T
I
R
H
G
S
G
I
V
C
L
C
I
T
E
D
R
R
K
Q
L
D
L
P
M
M
V
E
N
N
T
S
A
Y
G
T
G
F
T
V
T
I
E
--
A
-
A
-
E
G
V
T
-
T
G
V
S
A
A
D
R
V
T
T
V
R
A
A
I
K
D
G
A
K
P
S
D
L
N
R
P
G
H
V
F
P
L
R
A
Q
A
G
G
V
L
T
R
G
G
H
T
E
A
T
I
D
L
M
T
L
A
G
F
K
P
A
G
V
L
C
E
L
T
-
N
--
D
--
D
G
-----------
T
------------
M
A
R
A
P
E
C
I
A
F
A
G
Q
H
N
M
A
V
V
T
I
E
D
L
V
A
Y
R
Q
A
H
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
PsiBlast_CBE
63.94
46%
-74
- C4 -
-
4P6C
2
RIBB_VIBCH
B:
[36-234]
----
R
V
E
N
A
L
Q
A
L
R
E
G
R
G
V
L
L
L
D
D
E
D
R
E
N
E
G
D
I
I
Y
A
V
E
S
L
T
T
A
Q
M
A
L
M
I
R
E
C
S
G
I
V
C
L
C
L
T
E
A
Q
A
D
R
L
A
L
P
P
M
V
V
N
N
N
S
A
N
Q
T
A
F
T
V
S
I
E
--
A
-
K
-
H
G
V
T
-
T
G
V
S
A
Q
D
R
V
T
T
I
K
T
A
A
N
P
Q
A
K
P
E
D
L
A
R
P
G
H
V
F
P
L
R
A
R
A
G
G
V
L
A
R
R
G
H
T
E
G
T
V
D
L
M
Q
M
A
G
L
Q
P
A
G
V
L
C
E
L
T
-
N
--
P
--
D
G
-----------
S
------------
M
A
K
T
P
E
I
I
E
F
G
K
L
H
N
M
P
V
L
T
I
E
D
M
V
Q
Y
R
I
Q
F
D
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
63.90
46%
-85
- C4 -
-
4P6D
1
RIBB_VIBCH
A:
[35-233]
----
R
V
E
N
A
L
Q
A
L
R
E
G
R
G
V
L
L
L
D
D
E
D
R
E
N
E
G
D
I
I
Y
A
V
E
S
L
T
T
A
Q
M
A
L
M
I
R
E
C
S
G
I
V
C
L
C
L
T
E
A
Q
A
D
R
L
A
L
P
P
-------------
T
V
S
I
E
--
A
-
K
-
H
G
V
T
-
T
G
V
S
A
Q
D
R
V
T
T
I
K
T
A
A
N
P
Q
A
K
P
E
D
L
A
R
P
G
H
V
F
P
L
R
A
R
A
G
G
V
L
A
R
R
G
H
T
E
G
T
V
D
L
M
Q
M
A
G
L
Q
P
A
G
V
L
C
E
L
T
-
N
--
P
--
D
G
-----------
S
------------
M
A
K
T
P
E
I
I
E
F
G
K
L
H
N
M
P
V
L
T
I
E
D
M
V
Q
Y
R
I
Q
F
D
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
63.60
46%
-78
- C4 -
-
4P6P
2
RIBB_VIBCH
A:
[35-233]
----
R
V
E
N
A
L
Q
A
L
R
E
G
R
G
V
L
L
L
D
D
E
D
R
E
N
E
G
D
I
I
Y
A
V
E
S
L
T
T
A
Q
M
A
L
M
I
R
E
C
S
G
I
V
C
L
C
L
T
E
A
Q
A
D
R
L
A
L
P
P
M
V
V
N
N
N
S
A
N
Q
T
A
F
T
V
S
I
E
--
A
-
K
-
H
G
V
T
-
T
G
V
S
A
Q
D
R
V
T
T
I
K
T
A
A
N
P
Q
A
K
P
E
D
L
A
R
P
G
H
V
F
P
L
R
A
R
A
G
G
V
L
A
R
R
G
H
T
E
G
T
V
D
L
M
Q
M
A
G
L
Q
P
A
G
V
L
C
E
L
T
-
N
--
P
--
D
G
-----------
S
------------
M
A
K
T
P
E
I
I
E
F
G
K
L
H
N
M
P
V
L
T
I
E
D
M
V
Q
Y
R
I
Q
F
D
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
PsiBlast_CBE
62.86
45%
-85
- C4 -
-
3MIO
4
RIBBA_MYCTA
B:
[6-203]
----
S
V
E
R
A
V
A
D
I
A
A
G
K
A
V
I
V
I
D
D
E
D
R
E
N
E
G
D
L
I
F
A
A
E
K
A
T
P
E
M
V
A
F
M
V
R
Y
T
S
G
Y
L
C
V
P
L
D
G
A
I
C
D
R
L
G
L
L
P
M
------------
T
V
T
V
D
--
A
-
R
-
N
G
I
G
-
T
G
I
S
A
S
D
R
A
T
T
M
R
L
L
A
D
P
T
S
V
A
D
D
F
T
R
P
G
H
V
V
P
L
R
A
K
D
G
G
V
L
R
R
P
G
H
T
E
A
A
V
D
L
A
R
M
A
G
L
Q
P
A
G
A
I
C
E
I
V
-
S
--
Q
KD
E
G
-----------
S
------------
M
A
H
T
D
E
L
R
V
F
A
D
E
H
G
L
A
L
I
T
I
A
D
L
I
E
W
R
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
PsiBlast_CBE
62.63
46%
-81
- C4 -
-
4P77
2
RIBB_VIBCH
B:
[35-233]
----
R
V
E
N
A
L
Q
A
L
R
E
G
R
G
V
L
L
L
D
D
E
D
R
E
N
E
G
D
I
I
Y
A
V
E
S
L
T
T
A
Q
M
A
L
M
I
R
E
C
S
G
I
V
C
L
C
L
T
E
A
Q
A
D
R
L
A
L
P
P
M
V
V
-------
T
A
F
T
V
S
I
E
--
A
-
K
-
H
G
V
T
-
T
G
V
S
A
Q
D
R
V
T
T
I
K
T
A
A
N
P
Q
A
K
P
E
D
L
A
R
P
G
H
V
F
P
L
R
A
R
A
G
G
V
L
A
R
R
G
H
T
E
G
T
V
D
L
M
Q
M
A
G
L
Q
P
A
G
V
L
C
E
L
T
-
N
--
P
--
D
G
-----------
S
------------
M
A
K
T
P
E
I
I
E
F
G
K
L
H
N
M
P
V
L
T
I
E
D
M
V
Q
Y
R
I
Q
F
D
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
87
HHSearch
62.32
41%
-43
- C4 -
-
1K4O
1
RIB3_MAGO7
A:
[12-227]
--
F
D
A
I
P
D
V
I
Q
A
F
K
N
G
E
F
V
V
V
L
D
D
P
S
R
E
N
E
A
D
L
I
I
A
A
E
S
V
T
T
E
Q
M
A
F
M
V
R
H
S
S
G
L
I
C
A
P
L
T
P
E
R
T
T
A
L
D
L
P
Q
M
V
T
H
N
A
D
P
R
G
T
A
Y
T
V
S
V
D
--
A
E
H
P
S
-
T
T
-
T
G
I
S
A
H
D
R
A
L
A
C
R
M
L
A
A
P
D
A
Q
P
S
H
F
R
R
P
G
H
V
F
P
L
R
A
V
A
G
G
V
R
A
R
R
G
H
T
E
A
G
V
E
L
C
R
L
A
G
K
R
P
V
A
V
I
S
E
I
V
-
D
--
D
--
G
Q
EVEGRAVRAA
P
G
------------
M
L
R
G
D
E
C
V
A
F
A
R
R
W
G
L
K
V
C
T
I
E
D
M
I
A
H
V
E
K
T
E
G
K
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
91
HHSearch
62.17
46%
-81
* C4 *
-
3MIO
4
RIBBA_MYCTA
B:
[3-205]
-
R
L
D
S
V
E
R
A
V
A
D
I
A
A
G
K
A
V
I
V
I
D
D
E
D
R
E
N
E
G
D
L
I
F
A
A
E
K
A
T
P
E
M
V
A
F
M
V
R
Y
T
S
G
Y
L
C
V
P
L
D
G
A
I
C
D
R
L
G
L
L
P
M
------------
T
V
T
V
D
--
A
R
N
-
G
-
I
G
-
T
G
I
S
A
S
D
R
A
T
T
M
R
L
L
A
D
P
T
S
V
A
D
D
F
T
R
P
G
H
V
V
P
L
R
A
K
D
G
G
V
L
R
R
P
G
H
T
E
A
A
V
D
L
A
R
M
A
G
L
Q
P
A
G
A
I
C
E
I
V
-
S
QK
D
--
E
G
-----------
S
------------
M
A
H
T
D
E
L
R
V
F
A
D
E
H
G
L
A
L
I
T
I
A
D
L
I
E
W
R
R
K
H
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
92
HHSearch
61.97
46%
-84
- C4 -
-
3MIO
2
RIBBA_MYCTA
A:
[3-205]
-
R
L
D
S
V
E
R
A
V
A
D
I
A
A
G
K
A
V
I
V
I
D
D
E
D
R
E
N
E
G
D
L
I
F
A
A
E
K
A
T
P
E
M
V
A
F
M
V
R
Y
T
S
G
Y
L
C
V
P
L
D
G
A
I
C
D
R
L
G
L
L
P
M
Y
-----------
T
V
T
V
D
--
A
R
N
-
G
-
I
G
-
T
G
I
S
A
S
D
R
A
T
T
M
R
L
L
A
D
P
T
S
V
A
D
D
F
T
R
P
G
H
V
V
P
L
R
A
K
D
G
G
V
L
R
R
P
G
H
T
E
A
A
V
D
L
A
R
M
A
G
L
Q
P
A
G
A
I
C
E
I
V
-
S
QK
D
--
E
G
-----------
S
------------
M
A
H
T
D
E
L
R
V
F
A
D
E
H
G
L
A
L
I
T
I
A
D
L
I
E
W
R
R
K
H
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
PsiBlast_CBE
61.86
45%
-89
- C4 -
-
3MIO
2
RIBBA_MYCTA
A:
[6-203]
----
S
V
E
R
A
V
A
D
I
A
A
G
K
A
V
I
V
I
D
D
E
D
R
E
N
E
G
D
L
I
F
A
A
E
K
A
T
P
E
M
V
A
F
M
V
R
Y
T
S
G
Y
L
C
V
P
L
D
G
A
I
C
D
R
L
G
L
L
P
M
Y
-----------
T
V
T
V
D
--
A
-
R
-
N
G
I
G
-
T
G
I
S
A
S
D
R
A
T
T
M
R
L
L
A
D
P
T
S
V
A
D
D
F
T
R
P
G
H
V
V
P
L
R
A
K
D
G
G
V
L
R
R
P
G
H
T
E
A
A
V
D
L
A
R
M
A
G
L
Q
P
A
G
A
I
C
E
I
V
-
S
--
Q
KD
E
G
-----------
S
------------
M
A
H
T
D
E
L
R
V
F
A
D
E
H
G
L
A
L
I
T
I
A
D
L
I
E
W
R
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
39
PsiBlast_CBE
61.65
41%
-63
- C4 -
-
1K4O
1
RIB3_MAGO7
A:
[12-216]
--
F
D
A
I
P
D
V
I
Q
A
F
K
N
G
E
F
V
V
V
L
D
D
P
S
R
E
N
E
A
D
L
I
I
A
A
E
S
V
T
T
E
Q
M
A
F
M
V
R
H
S
S
G
L
I
C
A
P
L
T
P
E
R
T
T
A
L
D
L
P
Q
M
V
T
H
N
A
D
P
R
G
T
A
Y
T
V
S
V
D
A
E
H
-
P
-
S
-
T
T
-
T
G
I
S
A
H
D
R
A
L
A
C
R
M
L
A
A
P
D
A
Q
P
S
H
F
R
R
P
G
H
V
F
P
L
R
A
V
A
G
G
V
R
A
R
R
G
H
T
E
A
G
V
E
L
C
R
L
A
G
K
R
P
V
A
V
I
S
E
I
V
-
D
-----
D
G
-----------
Q
EVEGRAVRAA
P
G
M
L
R
G
D
E
C
V
A
F
A
R
R
W
G
L
K
V
C
T
I
E
D
M
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------