@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : spr0178: (2017-12-16 )
MCMFEVKEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTGTNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLADQVKEMEKTLLQTPDQLSFFELLTLVAFLYFRGQEVDLVLLEVGIGGLLDTTNVVTGELAVITSIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVNLYQAGQDFSVLNGDFSSSLLNLSQLNIGLEGVYQQENAALALQTFLLFMGEGKEAVDEQAVRKALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGSLKRKDYQGMLGYLTENLPQVELKMTGFDYQGSLDETDVTGYHVIPSYREFISSFEERADAQDLLFVTGSLYFISEVRGYLLDREQIN
Atome Classification :
(20 SA)
.........10.........20........30........40........50........60........70........80........90........100.----.-.....110----...---.--.....120.......130.......140.......150........160.......170.......180.......----190-..-----.......-200.......210....------...--220---.----..---.----.-------..-----230-------.----.--...--.--.-.-------.240.......250.......260.--.-.....270---...--.....280.-......290.--.-------------.--...-.300-.....----..310.......320.......330-.----..----.-...340.........350-...------......360-.------..------.....-.-------370--...---..----....380......------------.390.......400.......410......
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
M
C
M
F
E
V
K
E
W
L
-
H
S
RIGL
N
F
R
S
G
L
G
R
M
Q
Q
A
V
D
L
LGNPEQS
Y
P
I
I
H
V
TGTNGKG
S
T
I
A
F
M
R
E
L
F
MGHG
K
K
V
A
T
FTS
P
H
I
V
SIN
D
R
I
C
INGQPIA
D
A
D
F
I
R
L
A
D
Q
V
K
----
E
-
M
E
K
T
L
L------QTP---
D
--
Q
L
S
F
F
E
L
L
T
L
V
A
F
L
Y
FRGQE
V
D
L
V
L
L
EVGIGGLLDT-TNVVTG
E
L
A
V
I
T
SIGL
D
H
Q
E
T
L
G
D
S
L
E
A
I
A
E
QK
A
G
I
F
KA----G---
K
K
-----
A
V
I
AKLP-
P
E
A
R
L
V
C
Q
K
K
A
E
S
L
A
V
N
------
L
Y
Q--AGQ---D----
F
S
---
V
----L-------NG-----D---------
F
----
S
--
S
S
L
--
L
--
N
-
L
-------
S
Q
LNIGL
E
G
V
YQQE
N
A
A
L
A
L
Q
T
F
L
L
--
F
-MGE
G
K
E
A
----
V
D
E
--
Q
A
V
R
K
A
L
E
Q
-
T
H
W
A
G
R
L
E
RI--R-------------
P
--
Q
I
Y
-LDGA-HN
L
P
A
----
L
T
R
L
V
E
F
I
K
E
K
E
QEGYRP
Q
I
L
F
G
S
L-K----R
K
----
D
-
Y
Q
G
M
--
L
G
Y
L
TENL
P
Q
---
V
E
L
------
K
M
TGFDY---Q------GS------LDETD-V-------T----
G
Y
H---V
I
----
P
S
Y
R
E
F
I
S
S
F
E
E
R------------ADAQ
D
L
L
F
VTG
S
L
Y
F
I
S
E
V
R
G
Y
LLDREQIN
1
PsiBlast_PDB
94.46
33%
-49
- C2 -
-
1FGS
1
FPGS_LACCA
A:
[1-424]
M
N
Y
T
E
T
V
A
Y
I
-
H
S
F
P
R
L
A
--
G
D
H
R
R
I
L
T
L
L
H
A
L
G
N
P
Q
Q
Q
G
R
Y
I
H
V
T
G
T
N
G
K
G
S
A
A
N
A
I
A
H
V
L
E
A
S
G
L
T
V
G
L
Y
T
S
P
F
I
M
R
F
N
E
R
I
M
I
D
H
E
P
I
P
D
A
A
L
V
N
A
V
A
F
V
R
----
A
A
L
E
R
L
Q
Q
------
Q
Q
A
---
D
F
-
N
V
T
E
F
E
F
I
T
A
L
A
Y
W
Y
F
R
Q
R
Q
V
D
V
A
V
I
E
V
G
-----
D
S
-
T
N
V
I
T
P
V
V
S
V
L
T
E
V
A
L
D
-------
T
I
T
A
I
A
K
H
K
A
G
I
I
K
R
----
G
---
I
P
-----
V
V
T
G
N
L
V
-
P
D
A
A
A
V
V
A
A
K
V
A
T
T
G
S
Q
------
W
L
R
--
F
D
R
---
D
----
F
S
---
V
P
K
A
K
L
-------
H
G
W
G
Q
R
F
T
---------
Y
----
E
--
D
Q
D
--
G
--
R
-
I
-------
S
D
L
E
V
P
L
V
G
D
Y
Q
Q
R
N
M
A
I
A
I
Q
T
A
K
V
--
Y
-
A
K
Q
T
E
W
P
----
L
T
P
--
Q
N
I
R
Q
G
L
A
A
-
S
H
W
P
A
R
L
E
K
I
--
S
DT-----------
P
--
L
I
V
-
I
D
G
A
-
H
N
P
D
G
----
I
N
G
L
I
T
A
L
K
Q
L
F
S
Q
P
I
--
T
V
I
A
G
----------------
Y
A
A
M
--
A
D
R
L
T
A
A
F
S
T
---
V
Y
L
----------
V
P
V
---
P
------
G
T
------
P
R
-------------------------GRLK
D
S
W
Q
E
A
L
A
A
S
L
N
D
------------
V
P
D
Q
P
I
V
-
I
T
G
S
L
Y
L
A
S
A
V
R
Q
T
L
L
------
3
PsiBlast_PDB
92.10
33%
-45
- C2 -
-
2GCB
-
FPGS_LACCA
A:
[1-424]
M
N
Y
T
E
T
V
A
Y
I
-
H
S
F
P
R
L
A
K
T
G
D
H
R
R
I
L
T
L
L
H
A
L
G
N
P
Q
Q
Q
G
R
Y
I
H
V
T
G
T
N
G
K
S
T
A
A
N
A
I
A
H
V
L
E
A
S
G
L
T
V
G
L
Y
T
S
P
F
I
M
R
F
N
E
R
I
M
I
D
H
E
P
I
P
D
A
A
L
V
N
A
V
A
F
V
R
----
A
A
L
E
R
L
Q
Q
------
Q
Q
A
---
D
F
-
N
V
T
E
F
E
F
I
T
A
L
G
Y
W
Y
F
R
Q
R
Q
V
D
V
A
V
I
E
V
G
I
G
G
D
T
D
S
-
T
N
V
I
T
P
V
V
S
V
L
T
S
V
A
L
D
H
Q
K
L
L
G
H
T
I
T
A
I
A
K
H
K
A
G
I
I
K
R
----
G
---
I
P
-----
V
V
T
G
N
L
V
-
P
D
A
A
A
V
V
A
A
K
V
A
T
T
G
S
Q
------
W
L
R
--
F
D
R
---
D
----
F
S
---
V
P
K
A
K
L
-------
H
G
W
G
Q
R
F
T
---------
Y
----
E
--
D
Q
D
--
G
--
R
-
I
-------
S
D
L
E
V
P
L
V
G
D
Y
Q
Q
R
N
M
A
I
A
I
Q
T
A
K
V
--
Y
-
A
K
Q
T
E
W
P
----
L
T
P
--
Q
N
I
R
Q
G
L
A
A
-
S
H
W
P
A
R
L
E
K
I
--
S
DT-----------
P
--
L
I
V
-
I
D
G
A
-
H
N
P
D
G
----
I
N
G
L
I
T
A
L
K
Q
L
F
S
Q
P
I
--
T
V
I
A
G
I
L
-----------------
M
--
A
D
R
L
T
A
A
F
S
T
---
V
Y
L
----------
V
P
V
---
P
------
G
T
------
P
R
A
L
-----------------------RLK-
D
S
W
Q
E
A
L
A
A
S
L
N
D
------------
V
P
D
Q
P
I
V
-
I
T
G
S
L
Y
L
A
S
A
V
R
Q
T
L
L
------
2
PsiBlast_PDB
91.80
33%
-42
- C2 -
-
2GCA
-
FPGS_LACCA
A:
[1-424]
M
N
Y
T
E
T
V
A
Y
I
-
H
S
F
P
R
L
A
K
T
G
D
H
R
R
I
L
T
L
L
H
A
L
G
N
P
Q
Q
Q
G
R
Y
I
H
V
T
G
T
N
G
K
G
S
A
A
N
A
I
A
H
V
L
E
A
S
G
L
T
V
G
L
Y
T
S
P
F
I
M
R
F
N
E
R
I
M
I
D
H
E
P
I
P
D
A
A
L
V
N
A
V
A
F
V
R
----
A
A
L
E
R
L
Q
Q
------
Q
Q
A
---
D
F
-
N
V
T
E
F
E
F
I
T
A
L
G
Y
W
Y
F
R
Q
R
Q
V
D
V
A
V
I
E
V
G
I
G
G
D
T
D
S
-
T
N
V
I
T
P
V
V
S
V
L
T
E
V
A
L
D
H
Q
K
L
L
G
H
T
I
T
A
I
A
K
H
K
A
G
I
I
K
R
----
G
---
I
P
-----
V
V
T
G
N
L
V
-
P
D
A
A
A
V
V
A
A
K
V
A
T
T
G
S
Q
------
W
L
R
--
F
D
R
---
D
----
F
S
---
V
P
K
A
K
L
-------
H
G
W
G
Q
R
F
T
---------
Y
----
E
--
D
Q
D
--
G
--
R
-
I
-------
S
D
L
E
V
P
L
V
G
D
Y
Q
Q
R
N
M
A
I
A
I
Q
T
A
K
V
--
Y
-
A
K
Q
T
E
W
P
----
L
T
P
--
Q
N
I
R
Q
G
L
A
A
-
S
H
W
P
A
R
L
E
K
I
--
S
DT-----------
P
--
L
I
V
-
I
D
G
A
-
H
N
P
D
G
----
I
N
G
L
I
T
A
L
K
Q
L
F
S
Q
P
I
--
T
V
I
A
G
I
L
--------------
Y
A
A
M
--
A
D
R
L
T
A
A
F
S
T
---
V
Y
L
----------
V
P
V
---
P
------
G
T
------
P
R
A
L
-----------------------RLK-
D
S
W
Q
E
A
L
A
A
S
L
N
D
------------
V
P
D
Q
P
I
V
-
I
T
G
S
L
Y
L
A
S
A
V
R
Q
T
L
L
------
15
HHSearch
91.29
33%
-40
- C2 -
-
2GCA
-
FPGS_LACCA
A:
[1-425]
M
N
Y
T
E
T
V
A
Y
I
-
H
S
F
P
R
L
A
K
T
G
D
H
R
R
I
L
T
L
L
H
A
L
G
N
P
Q
Q
Q
G
R
Y
I
H
V
T
G
T
N
G
K
G
S
A
A
N
A
I
A
H
V
L
E
A
S
G
L
T
V
G
L
Y
T
S
P
F
I
M
R
F
N
E
R
I
M
I
D
H
E
P
I
P
D
A
A
L
V
N
A
V
A
F
V
R
----
A
-
A
L
E
R
L
Q
Q
Q
----
Q
A
D
---
F
--
N
V
T
E
F
E
F
I
T
A
L
G
Y
W
Y
F
R
Q
R
Q
V
D
V
A
V
I
E
V
G
I
G
G
D
T
D
S
-
T
N
V
I
T
P
V
V
S
V
L
T
E
V
A
L
D
H
Q
K
L
L
G
H
T
I
T
A
I
A
K
H
K
A
G
I
I
K
R
----
G
---
I
P
-----
V
V
T
G
N
L
V
-
P
D
A
A
A
V
V
A
A
K
V
A
T
T
G
S
Q
------
W
L
R
--
F
D
R
---
D
----
F
S
V--
P
----
K
A
K
L
H
GW-
G
Q
-----
R
---------
F
----
T
--
Y
E
D
QD
G
--
R
-
I
-------
S
D
L
E
V
P
L
V
G
D
Y
Q
Q
R
N
M
A
I
A
I
Q
T
A
K
V
--
Y
-
A
K
Q
T
E
W
P
----
L
T
P
--
Q
N
I
R
Q
G
L
A
A
-
S
H
W
P
A
R
L
E
K
I
--
S
DT-----------
P
--
L
I
V
-
I
D
G
A
-
H
N
P
D
G
----
I
N
G
L
I
T
A
L
K
Q
L
F
--
S
Q
P
I
T
V
I
A
G
I
L
--------------
Y
A
A
M
--
A
D
R
L
T
-
A
A
F
S
----
T
V
------
Y
L
V
P
V
P
G
----------
T
P
------
R
A
L
------------------
R
---
L
K
----
D
S
W
Q
E
A
L
A
A
S
L
N
-------------
D
V
P
D
Q
P
I
V
I
T
G
S
L
Y
L
A
S
A
V
R
Q
T
L
L
G
-----
17
HHSearch
89.56
31%
-47
- C2 -
-
1O5Z
2
?
A:
[13-434]
M
A
Y
L
E
V
L
R
Y
L
-
Y
H
K
----
V
K
P
G
L
E
R
I
S
M
L
L
S
K
L
G
N
P
H
L
E
Y
K
T
I
H
I
G
G
T
N
G
K
G
S
V
A
N
M
V
S
N
I
L
V
S
Q
G
Y
R
V
G
S
Y
Y
S
P
H
L
S
T
F
R
E
R
I
R
L
N
E
E
Y
I
S
E
E
D
V
V
K
I
Y
E
T
M
E
----
P
-
I
L
N
E
L
D
K-----
E
E
I
---
F
--
S
P
S
F
F
E
V
V
T
A
M
A
F
L
Y
F
A
E
K
N
V
D
I
A
V
L
E
V
G
L
G
G
R
L
D
A
-
T
N
V
V
F
P
L
C
S
T
I
V
T
V
D
R
-------
Y
T
I
E
Q
I
A
W
E
K
S
G
I
I
K
E
----
R
---
V
P
-----
L
V
T
G
E
R
K
-
R
E
A
L
K
V
M
E
D
V
A
R
K
K
S
--------
S
R
M
--
Y
V
I
---
D
KD--
F
S
V
K
V
K
----
S
LKLH---
E
N
-----
R
---------
F
----
D
--
Y
C
G
--
E
N
-
T
-
F
-------
E
D
L
V
L
T
M
N
G
P
H
Q
I
E
N
A
G
V
A
L
K
T
L
E
A
--
T
-
G
----------
L
P
L
S
E
K
A
I
R
E
G
L
K
N
-
A
K
N
L
G
R
F
E
I
L
--
E
K
NG----------
K
--
M
Y
I
-
L
D
G
A
-
H
N
P
H
G
----
A
E
S
L
V
R
S
L
K
L
Y
F
-
N
G
E
P
L
S
L
V
I
G
I
L
-
D
----
D
K
----
N
-
R
E
D
I
--
L
R
K
Y
T
-
G
I
F
E
----
R
V
------
I
V
T
R
V
P
S
PRM
K
------
D
M
------
N
S
L
V
D
M
A
K
K
F
F---
K
----
N
V
E
---
V
I
----
E
D
P
L
E
A
I
E
------------------
S
T
E
R
A
T
V
V
T
G
S
L
F
L
V
G
Y
V
R
E
F
L
T
T
G
----
5
PsiBlast_PDB
86.55
29%
-52
- C2 -
-
3PYZ
1
?
A:
[24-435]
-------
E
H
L
-
H
S
Q
---
P
I
E
L
G
L
E
R
V
K
Q
V
A
E
R
L
D
L
L
K
P
A
P
K
I
F
T
V
A
G
T
N
G
K
G
T
T
C
C
T
L
E
A
I
L
L
A
A
G
L
R
V
G
V
Y
S
S
P
H
L
L
R
Y
T
E
R
V
R
I
Q
G
Q
E
L
S
E
A
E
H
S
H
S
F
A
Q
I
E
----
A
-
G
R
G
D
I
----------------
S
L
T
Y
F
E
F
G
T
L
S
A
L
Q
L
F
K
Q
A
K
L
D
V
V
I
L
E
V
G
L
G
G
R
L
D
A
-
T
N
I
V
D
S
D
V
A
A
I
T
S
I
A
L
D
H
T
D
W
L
G
Y
D
R
E
S
I
G
R
E
K
A
G
V
F
R
G
----
G
---
K
P
-----
A
V
V
G
E
---
P
D
M
P
Q
S
I
A
D
V
A
A
E
L
G
A
Q
------
L
Y
R
R
D
V
A
W
---
K
----
F
S
Q
Q--------------
N
G
-----
W
---------
H
W
Q
C
G
E
--
R
Q
L
--
T
--
G
-
L
-------
P
V
P
N
V
P
L
------
A
N
A
A
----
T
A
L
A
--
V
-
L
H
Y
S
E
L
P
----
L
S
D
--
E
A
I
R
Q
G
L
Q
A
-
A
S
L
P
G
R
F
Q
V
V
SE
Q
-------------
P
--
L
L
I
-
L
D
V
A
-
H
N
P
H
A
A
R
Y
L
V
N
R
L
A
Q
V
I
-----
Q
G
-
K
V
R
A
V
V
G
M
L
-
S
----
D
K
----
D
-
I
A
G
T
--
L
A
C
L
S
E
R
V
D
E
W
Y
C
A
P
L
------
E
G
P
R
G
A
S
---
A
------
G
Q
------
L
A
E
H
L
-
V
-------
S
----
A
R
Q
F
SD
V
E
----
T
A
W
R
Q
A
M
----
Q
D
------------
A
D
T
Q
D
V
V
I
V
C
G
S
F
H
T
V
A
H
V
M
A
A
L
-------
19
HHSearch
84.76
27%
-55
- C2 -
-
3PYZ
1
?
A:
[16-436]
--
L
A
A
W
L
C
Y
L
-
E
H
L
H
S
Q
P
I
E
L
G
L
E
R
V
K
Q
V
A
E
R
L
D
L
L
K
P
A
P
K
I
F
T
V
A
G
T
N
G
K
G
T
T
C
C
T
L
E
A
I
L
L
A
A
G
L
R
V
G
V
Y
S
S
P
H
L
L
R
Y
T
E
R
V
R
I
Q
G
Q
E
L
S
E
A
E
H
S
H
S
F
A
Q
I
E
----
A
-
G
R
-----------
G
D
---
I
--
S
L
T
Y
F
E
F
G
T
L
S
A
L
Q
L
F
K
Q
A
K
L
D
V
V
I
L
E
V
G
L
G
G
R
L
D
A
-
T
N
I
V
D
S
D
V
A
A
I
T
S
I
A
L
D
H
T
D
W
L
G
Y
D
R
E
S
I
G
R
E
K
A
G
V
F
R
G
----
G
---
K
P
-----
A
V
V
G
E
P
D
M
P
Q
S
---
I
A
D
V
A
A
E
L
G
A
Q
L
Y
R
R
DV
A
W
K
--
F
S
Q
---
Q
-----------------------
N
-----
G
---------
W
----
H
--
W
Q
C
--
G
--
E
-
R
-------
Q
L
T
G
L
P
V
P
-
N
V
P
L
A
N
A
A
T
A
L
A
V
L
H
Y
S
E
L
-
P
----------
L
S
D
--
E
A
I
R
Q
G
L
Q
A
-
A
S
L
P
G
R
F
Q
V
V
--
S
EQ-----------
P
--
L
L
I
-
L
D
V
A
-
H
N
P
H
A
----
A
R
Y
L
V
N
R
L
A
Q
V
I
--
Q
G
K
V
R
A
V
V
G
M
L
-
S
----
D
K
----
D
-
I
A
G
T
--
L
A
C
L
S
-
E
R
V
D
----
E
W
------
Y
C
A
P
L
E
G
PR
G
A
------
S
A
------
G
Q
L
A
E
H
L
-------
V
----
S
A
R
---
Q
F
----
S
D
V
E
T
A
W
R
Q
A
M
Q
D
------------
A
D
T
Q
D
V
V
I
V
C
G
S
F
H
T
V
A
H
V
M
A
A
L
H
------
18
HHSearch
83.04
27%
-58
- C2 -
-
3NRS
7
?
A:
[16-436]
--
L
A
A
W
L
C
Y
L
-
E
H
L
-------
G
L
E
R
V
K
Q
V
A
E
R
L
D
L
L
K
P
A
P
K
I
F
T
V
A
G
T
N
G
K
G
T
T
C
C
T
L
E
A
I
L
L
A
A
G
L
R
V
G
V
Y
S
S
P
H
L
L
R
Y
T
E
R
V
R
I
Q
G
Q
E
L
S
E
A
E
H
S
H
S
F
A
Q
I
E
----
A
-
G
R
-----------
G
D
---
I
--
S
L
T
Y
F
E
F
G
T
L
S
A
L
Q
L
F
K
Q
A
K
L
D
V
V
I
L
E
V
G
L
G
G
R
L
D
A
-
T
N
I
V
D
S
D
V
A
A
I
T
S
I
A
L
D
H
T
D
W
L
G
Y
D
R
E
S
I
G
R
E
K
A
G
V
F
R
G
----
G
---
K
P
-----
A
V
V
G
E
P
D
M
P
Q
S
---
I
A
D
V
A
A
E
L
G
A
Q
L
Y
R
R
DV
A
W
K
--
F
S
Q
---------------------------
N
-----
G
---------
W
----
H
--
W
Q
C
--
G
--
E
-
R
-------
Q
L
T
G
L
P
V
P
-
N
V
P
L
A
N
A
A
T
A
L
A
V
L
H
Y
S
E
L
-
P
----------
L
S
D
--
E
A
I
R
Q
G
L
Q
A
-
A
S
L
P
G
R
F
Q
V
V
--
S
EQ-----------
P
--
L
L
I
-
L
D
V
A
-
H
N
P
H
A
----
A
R
Y
L
V
N
R
L
A
Q
V
I
---
G
K
V
R
A
V
V
G
M
L
-
S
----
D
K
----
D
-
I
A
G
T
--
L
A
C
L
S
-
E
R
V
D
----
E
W
------
Y
C
A
P
L
E
G
PRG
A
------
S
A
------
G
Q
L
A
E
H
L
-------
V
----
S
A
R
---
Q
F
----
S
D
V
E
T
A
W
R
Q
A
M
Q
D
------------
A
D
T
Q
D
V
V
I
V
C
G
S
F
H
T
V
A
H
V
M
A
A
L
H
------
6
PsiBlast_PDB
82.51
29%
-45
- C2 -
-
3QCZ
4
?
A:
[24-435]
-------
E
H
L
-
H
S
------
E
L
G
L
E
R
V
K
Q
V
A
E
R
L
D
L
L
K
P
A
P
K
I
F
T
V
A
G
T
N
G
K
G
T
T
C
C
T
L
E
A
I
L
L
A
A
G
L
R
V
G
V
Y
S
S
P
H
L
L
R
Y
T
E
R
V
R
I
Q
G
Q
E
L
S
E
A
E
H
S
H
S
F
A
Q
I
E
----
A
-
G
R
G
D
I
----------------
S
L
T
Y
F
E
F
G
T
L
S
A
L
Q
L
F
K
Q
A
K
L
D
V
V
I
L
E
V
G
L
G
G
R
L
D
A
-
T
N
I
V
D
S
D
V
A
A
I
T
S
I
A
L
D
H
T
D
W
L
G
Y
D
R
E
S
I
G
R
E
K
A
G
V
F
R
G
----
G
---
K
P
-----
A
V
V
G
E
---
P
D
M
P
Q
S
I
A
D
V
A
A
E
L
G
A
Q
------
L
Y
R
R
D
V
A
W
---
K
----
F
S
Q---------------
N
G
-----
W
---------
H
W
Q
C
G
E
--
R
Q
L
--
T
--
G
-
L
-------
P
V
P
N
V
P
L
------
A
N
A
A
----
T
A
L
A
--
V
-
L
H
Y
S
E
L
P
----
L
S
D
--
E
A
I
R
Q
G
L
Q
A
-
A
S
L
P
G
R
F
Q
V
V
SE
Q
-------------
P
--
L
L
I
-
L
D
V
A
-
H
N
P
H
A
A
R
Y
L
V
N
R
L
A
Q
V
I
-----
Q
G
-
K
V
R
A
V
V
G
M
L
-
S
----
D
K
----
D
-
I
A
G
T
--
L
A
C
L
S
E
R
V
D
E
W
Y
C
A
P
L
------
E
G
P
R
G
A
S
---
A
------
G
Q
------
L
A
E
H
L
-
V
-------
S
----
A
R
Q
F
SD
V
E
----
T
A
W
R
Q
A
M
----
Q
D
------------
A
D
T
Q
D
V
V
I
V
C
G
S
F
H
T
V
A
H
V
M
A
A
L
-------
14
HHSearch
81.52
29%
-24
- C2 -
-
2VOS
3
FOLC_MYCTU
A:
[27-486]
--
L
L
Q
V
E
H
L
L
-
D
Q
R
W
--
R
I
D
P
S
L
T
R
I
S
A
L
M
D
L
L
G
S
P
Q
R
S
Y
P
S
I
H
I
A
G
T
N
G
K
T
S
V
A
R
M
V
D
A
L
V
T
A
L
H
R
R
T
G
R
T
T
S
P
H
L
Q
S
P
V
E
R
I
S
I
D
G
K
P
I
S
P
A
Q
Y
V
A
T
Y
R
E
I
E
----
P
-
L
V
A
L
I
D
Q
Q
S
Q
A
S------
P
--
A
M
S
K
F
E
V
L
T
A
M
A
F
A
A
F
A
D
A
P
V
D
V
A
V
V
E
V
G
M
G
G
R
W
D
A
-
T
N
V
I
N
A
P
V
A
V
I
T
P
I
S
I
D
H
V
D
Y
L
G
A
D
I
A
G
I
A
G
E
K
A
G
I
I
T
R
APSP
D
---
T
V
-----
A
V
I
G
R
Q
V
-
P
K
V
M
E
V
L
L
A
E
S
V
R
---
A
------
D
A
S
--
V
A
R
E
DS
E
----
F
A
V--
L
----
R
R
Q
I
A
---
V
G
-----
G
Q
V
-------
L
----
Q
--
L
Q
G
--
L
GG
V
-
Y
-------
S
D
I
Y
L
P
L
H
G
E
H
Q
A
H
N
A
V
L
A
L
A
S
V
E
A
--
F
F
G
A
----
Q
----
L
D
G
--
D
A
V
R
A
G
F
A
A
-
V
T
S
P
G
R
L
E
R
M
--
R
SA-----------
P
--
T
V
F
-
I
D
A
A
-
H
N
P
A
G
----
A
S
A
L
A
Q
T
L
A
H
E
F
-
D
F
R
F
L
V
G
V
L
S
V
L
-
G
----
D
K
----
D
-
V
D
G
I
--
L
A
A
L
E
-
P
V
F
D
----
S
V
------
V
V
T
H
N
G
S
PRA
L
------
D
V
------
E
A
L
A
L
A
A
G
E
R
FGP-
D
----
R
V
R
---
T
A
----
E
N
L
R
D
A
I
D
V
A
T
S
L
V
D
D
A
A
A
DPDVAG---
R
T
G
I
V
I
T
G
S
V
V
T
A
G
A
A
R
T
L
F
G
R
D
P
---
11
Fugue
76.29
34%
-56
- C2 -
-
1FGS
1
?
?:
[1-314]
M
N
Y
T
E
T
V
A
Y
I
-
H
S
F
--
P
R
L
A
G
D
H
R
R
I
L
T
L
L
H
A
L
G
N
P
Q
Q
Q
G
R
Y
I
H
V
T
G
T
N
G
K
G
S
A
A
N
A
I
A
H
V
L
E
A
S
G
L
T
V
G
L
Y
T
S
P
F
I
M
R
F
N
E
R
I
M
I
D
H
E
P
I
P
D
A
A
L
V
N
A
V
A
F
V
R
----
A
-
A
L
E
R
L
Q
------
Q
Q
Q
---
A
D
F
N
V
T
E
F
E
F
I
T
A
L
A
Y
W
Y
F
R
Q
R
Q
V
D
V
A
V
I
E
V
G
-----
D
S
-
T
N
V
I
T
P
V
V
S
V
L
T
E
V
A
L
D
T
-------
I
T
A
I
A
K
H
K
A
G
I
I
K
R
----
G
---
I
P
-----
V
V
T
G
N
L
V
-
P
D
A
A
A
V
V
A
A
K
V
A
T
T
G
S
Q
------
W
L
R
--
F
D
R
---
D
----
F
S
---
V
----
P
-------
K
A
-----
K
L
H
GW
G
Q
R
F
T
Y
----
E
--
D
Q
D
--
G
--
R
-
I
-------
S
D
L
E
V
P
L
V
G
D
Y
Q
Q
R
N
M
A
I
A
I
Q
T
A
K
V
--
Y
-
A
K
Q
T
E
W
P
----
L
T
P
--
Q
N
I
R
Q
G
L
A
A
-
S
H
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
75.77
31%
-5
- C2 -
-
1O5Z
2
?
A:
[13-431]
M
A
Y
L
E
V
L
R
Y
L
Y
H
K
-----
V
K
P
G
L
E
R
I
S
M
L
L
S
K
L
G
N
P
H
L
E
Y
K
T
I
H
I
G
G
T
N
G
K
G
S
V
A
N
M
V
S
N
I
L
V
S
Q
G
Y
R
V
G
S
Y
Y
S
P
H
L
S
T
F
R
E
R
I
R
L
N
E
E
Y
I
S
E
E
D
V
V
K
I
Y
E
T
M
E
P
I
L
N
E
-
L
D
K
E
E
I
------
F
S
P
--------
S
F
F
E
V
V
T
A
M
A
F
L
Y
F
A
E
K
N
V
D
I
A
V
L
E
V
G
L
G
G
R
L
D
A
-
T
N
V
V
F
P
L
C
S
T
I
V
T
V
D
R
-------
Y
T
I
E
Q
I
A
W
E
K
S
G
I
I
K
E
----
R
---
V
P
-----
L
V
T
G
E
R
K
-
R
E
A
L
K
V
M
E
D
V
A
R
K
K
S
S
R
------
M
Y
V
--
I
D
K
---
D
----
F
S
---
V
----
K
V
KSLKLH
E
N
-----
R
---------
F
----
D
--
Y
C
G
--
E
--
N
T
F
-------
E
D
L
V
L
T
M
N
G
P
H
Q
I
E
N
A
G
V
A
L
K
T
L
-----------
E
A
T
GLP
L
S
E
--
K
A
I
R
E
G
L
K
N
-
A
K
N
L
G
R
F
E
I
L
--
E
-------------
K
NG
K
M
Y
I
L
D
G
A
-
H
N
P
H
G
----
A
E
S
L
V
R
S
L
K
L
Y
F
N
-
G
E
P
L
S
L
V
I
G
I
L
-
D
----
D
K
----
N
-
R
E
D
I
--
L
R
K
Y
T
G
I
F
E
R
---
V
I
V
T
R
VPSP
R
M
K
D
M
N
S
---
L
------
V
D
------
M
A
K
K
F
-
F
-------
K
----
N
V
E
---
V
I
----
E
D
P
L
E
A
I
E
S
-
T
E
R
------------
A
T
V
-----
V
T
G
S
L
F
L
V
G
Y
V
R
E
F
L
-------
7
PsiBlast_PDB
75.57
31%
-45
- C2 -
-
2VOS
3
FOLC_MYCTU
A:
[36-398]
------
Q
R
W
----
R
I
D
P
S
----
L
T
R
I
S
A
L
M
D
L
L
G
S
P
Q
R
S
Y
P
S
I
H
I
A
G
T
N
G
K
T
S
V
A
R
M
V
D
A
L
V
T
A
L
H
R
R
T
G
R
T
T
S
P
H
L
Q
S
P
V
E
R
I
S
I
D
G
K
P
I
S
P
A
Q
Y
V
A
T
Y
R
E
I
E
----
P
-
L
V
A
L
I
D
------
Q
Q
S
Q
A
S
P
--
A
M
S
K
F
E
V
L
T
A
M
A
F
A
A
F
A
D
A
P
V
D
V
A
V
V
E
V
G
M
G
G
R
W
D
A
-
T
N
V
I
N
A
P
V
A
V
I
T
P
I
S
I
D
H
V
D
Y
L
G
A
D
I
A
G
I
A
G
E
K
A
G
I
I
T
R
----
A
---
P
-SP
D
T
V
A
V
I
G
R
Q
V
-
P
K
V
M
E
V
L
L
A
E
S
V
R
A
D
A
S
------
V
A
R
--
E
D
S
---
E
----
F
A
---
V
----
L
-------
R
R
-----
Q
---------
I
----
A
VG
G
Q
V
--
L
--
Q
-
L
Q
G
LGGVY
S
D
I
Y
L
P
L
H
G
E
H
Q
A
H
N
A
V
L
A
L
A
S
V
E
A
--
F
-
F
G
A
---
Q
----
L
D
G
--
D
A
V
R
A
G
F
A
A
-
V
T
S
P
G
R
L
E
R
M
--
R
SA-----------
P
--
T
V
F
-
I
D
A
A
-
H
N
P
A
G
----
A
S
A
L
A
Q
T
L
A
H
E
----
F
D
F
R
F
L
V
G
V
L
-
S
V
L
G-
D
K
----
D
-
V
D
G
I
--
L
A
A
L
---------------------------------------------------------------------------------------------------------------------------------
38
HHSearch
52.00
17%
-30
- C2 -
-
2F00
-
MURC_ECOLI
B:
[118-470]
--------------------------------------
F
R
H
G
I
A
I
A
G
T
H
G
K
T
T
T
T
A
M
V
S
S
I
Y
A
E
A
G
L
D
P
T
F
--------------
V
N
G
G
L
V
K
------------------------------------------
A
A
G
V
H
A
-------
R
L
G
H
G
R
Y
L
I
A
E
A
D
E
S
D
A
S
F
---
L
H
L
Q
P
M
V
A
I
V
T
N
I
E
A
D
H
M
D
T
Y
Q
G
D
F
E
N
L
K
Q
T
F
I
N
F
L
H
N
LPF-
Y
---
G
R
-----
A
V
M
C
V
D
D
-
P
V
I
R
E
-
L
L
P
R
V
---
G
R
Q
------
T
T
T
--
Y
G
F
---
S
EDAD
V
R
V--
E
----
D
YQQIGP-
Q
G
-----
H
---------
F
----
T
--
L
L
R
QD
K
--
E
-
P
-------
M
R
V
T
L
N
A
P
G
R
H
N
A
L
N
A
A
A
A
V
A
V
A
T
E
--
E
-
G
----------
I
D
D
--
E
A
I
L
R
A
L
E
S
F
Q
G
T
G
R
R
F
D
F
L
--
G
EFPLEPVNGKSGT
A
--
M
L
V
-
D
D
Y
G
-
H
H
P
T
E
----
V
D
A
T
I
K
A
A
R
A
G
W
-
P
D
K
N
L
V
M
L
F
Q
P
H
-
R
FTR-
T
R
----
D
L
Y
D
D
F
--
A
N
V
L
T
--
Q
V
D
----
T
L
------
L
M
L
E
V
Y
P
AG-
E
------
A
P
IPGADS
R
S
L
C
R
T
I
RGRGK--
I
----
D
P
I
---
L
V
----
P
D
P
A
R
V
A
E
M
L
A
P
V
------------
L
T
G
N
D
L
I
L
V
Q
G
A
G
N
I
G
K
-------------
40
HHSearch
50.44
15%
-26
- C2 -
-
1P3D
2
MURC_HAEIN
A:
[117-470]
--------------------------------------
F
R
H
G
I
A
V
A
G
T
H
G
K
T
T
T
T
A
M
I
S
M
I
Y
T
Q
A
K
L
D
P
T
F
--------------
V
N
G
G
L
V
K
---------------------------------------
S
A
G
-
K
N
A
---------
H
L
G
A
S
R
Y
L
I
A
E
A
D
E
S
D
A
S
---
F
L
H
L
Q
P
M
V
S
V
V
T
N
M
E
P
D
H
M
D
T
Y
E
G
D
F
E
K
M
K
A
T
Y
V
K
F
L
H
N
LPF-
Y
---
G
L
-----
A
V
M
C
A
D
D
-
P
V
L
M
E
-
L
V
P
K
V
---
G
R
Q
------
V
I
T
--
Y
G
F
---
S
EQAD
Y
R
I--
E
----
D
Y
E
Q
T
GF-
Q
G
-----
H
---------
Y
----
T
--
V
I
C
PN
N
--
E
-
R
-------
I
N
V
L
L
N
V
P
G
K
H
N
A
L
N
A
T
A
A
L
A
V
A
K
E
--
E
-
G
----------
I
A
N
--
E
A
I
L
E
A
L
A
D
F
Q
G
A
G
R
R
F
D
Q
L
--
G
E
F
I
R
PN
G
K
-----
V
--
R
L
V
-
D
D
Y
G
-
H
H
P
T
E
----
V
G
V
T
I
K
A
A
R
E
G
W
-
G
D
K
R
I
V
M
I
F
Q
P
H
-
R
----
Y
S
R
T
R
D
L
-
F
D
D
F
--
V
Q
V
L
S
--
Q
V
D
----
A
L
------
I
M
L
D
V
Y
A
AG-
E
APIVGA
D
S
------
K
S
L
C
R
S
I
R
------
N
L
GK
V
D
P
I
---
L
V
----
S
D
T
S
Q
L
G
D
V
L
D
Q
I
------------
I
Q
D
G
D
L
I
L
A
Q
G
A
G
S
V
S
K
I
S
R
G
L
A
-------
39
HHSearch
49.72
15%
-28
* C2 *
-
1GQY
1
MURC_HAEIN
B:
[117-470]
--------------------------------------
F
R
H
G
I
A
V
A
G
T
H
G
K
T
T
T
T
A
M
I
S
M
I
Y
T
Q
A
K
L
D
P
T
F
--------------
V
N
G
G
L
V
K
---------------------------------------
S
A
G
-
K
N
A
---------
H
L
G
A
S
R
Y
L
I
A
E
A
D
E
S
D
A
S
---
F
L
H
L
Q
P
M
V
S
V
V
T
N
M
E
P
D
H
M
D
T
Y
E
G
D
F
E
K
M
K
A
T
Y
V
K
F
L
H
N
LPF-
Y
---
G
L
-----
A
V
M
C
A
D
D
-
P
V
L
M
E
-
L
V
P
K
V
---
G
R
Q
------
V
I
T
--
Y
G
F
---
S
EQAD
Y
R
I--
E
----
D
Y
E
Q
T
GF-
Q
G
-----
H
---------
Y
----
T
--
V
I
C
PN
N
--
E
-
R
-------
I
N
V
L
L
N
V
P
G
K
H
N
A
L
N
A
T
A
A
L
A
V
A
K
E
--
E
-
G
----------
I
A
N
--
E
A
I
L
E
A
L
A
D
F
Q
G
A
G
R
R
F
D
Q
L
--
G
E
F
I
R
PN
G
K
-----
V
--
R
L
V
-
D
D
Y
G
-
H
H
P
T
E
----
V
G
V
T
I
K
A
A
R
E
G
W
-
G
D
K
R
I
V
M
I
F
Q
P
H
-
R
----
Y
S
R
T
R
D
L
-
F
D
D
F
--
V
Q
V
L
S
--
Q
V
D
----
A
L
------
I
M
L
D
V
Y
A
AG-
E
APIVGA
D
S
------
K
S
L
C
R
S
I
R
------
N
L
GK
V
D
P
I
---
L
V
----
S
D
T
S
Q
L
G
D
V
L
D
Q
I
------------
I
Q
D
G
D
L
I
L
A
Q
G
A
G
S
V
S
K
I
S
R
G
L
A
-------
24
HHSearch
49.49
21%
-13
- C2 -
-
4BUB
1
MURE_THEMA
B:
[96-458]
--------------------------------
F
E
D
P
W
K
D
V
L
T
F
G
V
T
G
T
N
G
K
T
T
T
T
M
M
I
Y
H
M
L
T
S
L
G
E
R
G
S
V
L
T
T
A
V
-----
K
R
I
L
G
N
S
Y
Y
D
--------------------------------
D
I
---
T
--
T
P
D
A
I
T
I
L
S
A
M
K
--
E
N
R
E
G
G
G
K
F
F
A
L
E
V
S
S
H
A
L
V
Q
Q
R
V
E
G
V
R
F
D
V
G
I
F
T
N
I
S
R
D
H
L
D
F
H
G
-
T
F
E
N
Y
L
K
A
K
L
H
L
F
D
L
LKD-
D
---
G
V
-----
A
V
L
N
E
S
L
-
A
D
A
---
F
N
R
-----
K
S
R
------
K
I
T
--
F
G
T
---
S
KNAD
Y
R
L
--
G
----
N
IEVSWE-
G
T
-----
Q
---------
F
----
V
--
L
E
T
--
P
D-
G
-
L
-------
L
K
V
F
T
R
A
I
G
D
F
N
A
Y
N
A
A
A
A
I
A
A
L
H
Q
--
L
-
G
----------
Y
D
P
--
K
D
L
A
S
S
L
E
T
F
T
G
V
E
G
R
F
E
V
V
--
R
GAKKIG-------
L
--
N
V
V
-
V
D
F
A
-
H
S
P
D
A
----
L
E
K
L
L
K
N
V
R
K
I
S
--
Q
G
R
V
I
V
V
F
G
A
G
-
G
NS--
D
R
----
G
-
K
R
P
M
--
M
S
E
V
A
S
K
L
A
D
----
V
V
------
I
L
T
T
D
D
P
RG-
E
------
D
P
------
E
Q
I
M
E
D
L
I
K
G
IDKR
K
----
P
Y
L
---
V
L
----
F
D
R
R
E
A
I
E
T
A
L
T
I
------------
A
N
R
G
D
S
V
V
I
A
G
R
G
H
E
R
Y
-------------
33
HHSearch
48.98
18%
-39
- C2 -
-
3LK7
-
MURD_STRA5
A:
[111-437]
--------------------------------------
E
S
Q
L
I
G
I
T
G
S
N
G
K
T
T
T
T
T
M
I
A
E
V
L
N
A
G
G
Q
R
G
L
-
L
A
G
N
----------
I
-
G
----------------------------------------
F
--
P
A
S
--
E
V
V
-------
Q
A
A
N
D
K
D
T
L
V
M
E
L
S
S
F
Q
L
M
G
--
V
K
E
F
R
P
H
I
A
V
I
T
N
L
M
P
T
H
L
D
Y
H
G
-
S
F
E
D
Y
V
A
A
K
W
N
I
Q
N
Q
----
M
SSS
D
F
-----
L
V
L
N
F
N
Q
-
G
I
S
K
E
-
L
A
K
T
T
---
K
A
T
------
I
V
P
--
F
S
T
---
T
----
E
K
---
V
----
D
G
A
Y
V
Q
--
D
K
-----
Q
---------
L
----
F
--
Y
K
G
--
E
--
N
I
M
-------
S
V
D
D
I
G
V
P
G
S
H
N
V
E
N
A
L
A
T
I
A
V
A
K
L
--
A
-
G
----------
I
S
N
--
Q
V
I
R
E
T
L
S
N
F
G
G
V
K
H
R
L
Q
S
L
--
G
KVHG---------
I
--
S
F
Y
-
N
D
S
K
S
T
N
I
L
A
----
T
Q
K
A
L
S
G
F
D
N
-----
T
K
V
I
L
I
A
G
G
L
D
R
----
G
N
----
E
-
F
D
E
L
--
I
P
D
I
T
-
G
-
L
K
----
H
M
------
V
V
L
G
E
S
A
------------------
S
R
V
K
R
A
A
Q
K
-----
A
G
V
--
T
Y
S
---
D
A
----
L
D
V
R
D
A
V
H
K
A
Y
E
V
------------
A
Q
Q
G
D
V
I
L
L
S
P
A
N
A
S
W
D
M
Y
K
N
F
E
V
R
-----
34
HHSearch
48.43
17%
-37
- C2 -
-
1J6U
-
MURC_THEMA
A:
[101-439]
--------------------------------------
K
K
E
E
F
A
V
T
G
T
D
G
K
T
T
T
T
A
M
V
A
H
V
L
K
H
L
R
K
S
P
T
V
F
-------------
L
G
G
I
M
------------------------------------------
D
S
-
L
E
H
G
-------
N
Y
E
K
G
N
G
P
V
V
Y
E
L
D
E
S
E
--
E
F
-
F
S
E
F
S
P
N
Y
L
I
I
T
N
A
R
G
D
H
L
E
N
Y
G
N
S
L
T
R
Y
R
S
A
F
E
K
I
S
R
N
----
T
---
D
L
-----
V
V
T
F
A
E
D
-
E
L
T
S
H
-
L
G
D
V
T
F
G
V
K
K
G
------
T
Y
T
--
L
E
M
---
R
----
S
A
S
--
R
----
A
-------
E
Q
-----
K
---------
A
----
M
--
V
E
K
--
N
GK
R
-
Y
-------
L
E
L
K
L
K
V
P
G
F
H
N
V
L
N
A
L
A
V
I
A
L
F
D
S
--
L
-
G
----------
Y
D
L
--
A
P
V
L
E
A
L
E
E
F
R
G
V
H
R
R
F
S
I
A
--
F
HDPETN-------
I
--
Y
V
I
-
D
D
Y
A
-
H
T
P
D
E
----
I
R
N
L
L
Q
T
A
K
E
V
F
-
E
N
E
K
I
V
V
I
F
Q
P
H
-
R
----------------G
N
F
A
K
A
L
-
Q
L
A
D
----
E
V
------
V
V
T
E
V
Y
D
----------
S
G
------
K
M
I
W
D
S
L
K
S
L
G---
K
----
E
A
Y
---
F
V
----
E
K
L
P
E
L
E
K
V
I
--
S
------------
V
S
E
N
T
V
F
L
F
V
G
A
G
D
I
I
Y
S
S
R
R
F
V
-------
41
HHSearch
46.64
17%
-36
- C2 -
-
4HV4
2
MURC_YERPE
B:
[121-472]
--------------------------------------
Y
R
H
G
I
A
V
A
G
T
H
G
K
T
T
T
T
A
M
L
S
S
I
Y
A
E
A
G
L
D
P
T
F
--------------
V
N
G
G
L
V
K
------------------------------------------
A
A
G
T
H
-------
A
R
L
G
S
S
R
Y
L
I
A
E
A
D
E
S
D
A
S
---
F
L
H
L
Q
P
M
V
A
I
V
T
N
I
E
A
D
-------
D
F
E
N
L
K
Q
T
F
I
N
F
L
H
N
LPF-
Y
---
G
R
-----
A
V
M
C
I
D
D
-
P
V
V
R
E
-
L
L
P
R
V
---
G
R
H
------
I
T
T
--
Y
G
F
---
S
DDAD
V
Q
I
--
A
----
S
Y
R
Q
E
GP-
Q
G
-----
H
---------
F
----
T
--
L
R
R
--
Q
DK
P
-
L
-------
I
E
V
T
L
N
A
P
G
R
H
N
A
L
N
A
A
A
A
V
A
V
A
T
E
--
E
-
G
----------
I
E
D
--
E
D
I
L
R
A
L
V
G
F
Q
G
T
G
R
R
F
D
F
L
--
G
N
F
P
LAPVNGK
E
G
S
A
--
M
L
V
-
D
D
Y
G
-
H
H
P
T
E
----
V
D
A
T
I
K
A
A
R
A
G
W
-
P
D
K
R
I
V
M
L
F
Q
P
H
-
R
Y
T
R
T
R
D
----
L
-
Y
D
D
F
--
A
N
V
L
S
-
Q
-
V
D
----
V
L
------
L
M
L
D
V
Y
A
AG-
E
PPIPGA
D
S
------
R
A
L
C
R
T
I
R
N
R
GK--
L
----
D
P
I
---
L
V
----
P
D
S
E
S
A
P
E
M
L
A
Q
I
------------
L
N
G
E
D
L
I
L
V
Q
G
A
G
N
I
G
--------------