@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : spr0182: (2017-12-16 )
MNRRNDMSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWSTLVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGGFFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLALPFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLGHRRFVHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKILENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHASYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLLSVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILSPLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKVYKIK
Atome Classification :
(20 SA)
-----------------------------------.........10.----.......20........30........40........50..----------------------....---..-60-.-..---.---.....70....----....80....--..-----..90--.--------.......100----.-...-----.-..110..---.....120.......130.......140.......150.-.--.--..--.--.160---..--.------......170.....----..180-------..-----------.----.....190-----.......200.......210.......220....-...230----.-----.......240-........250.......260.......270....-----...280.......------------290.......300.......310.......320..-......330.......340....-...350.....---..360...-....370.......-------------380.......---390.......-400.......---410.......420.----.....----------.---------430....-----..-.440..--.....450.-.-..---.----..460-.-.-...-----------..-------..470.......-----.480..-.....490.......500.....-----------..510......----------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
-----------------------------------MNRRND
M
S
V
Y
G
R
----
V
E
E
V
H
KENREP
L
E
Y
Q
I
E
Q
E
SHHRESSRLP
L
V
K
I
L
L
W
S
T
L
V
T
----------------------
G
I
T
L
---
G
V
-
P
--
L
-
L
L
---
D
---
L
M
S
A
Q
E
V
Q
D
F
Y
----AGWALHQTG
K
--
I
Y
-----
S
D
YY--G--------S
Q
G
L
L
Y
Y
L
L
T
----
Y
-
V
SQ-----G-
G
F
F
F
A
I
F
---
E
W
L
A
L
VAG
G
F
F
L
FRSAD
T
L
TEQGDQAG
H
L
V
T
I
F
Y
M
L
V
T
G
-L--A--FG--
G
--
G
Y
-----
A
T
--
L
------
L
A
L
P
F
L
F
A
A
F
S
L
V
A
----
A
Y
LS--------NP-----------S----HDK
G
F
V
R
I
-----
G
L
ALAG
G
F
F
F
A
P
L
S
S
L
L
F
I
A
V
V
S
L
G
L
L
V
F
NLG
H
R
-
R
F
V
H
G
-----
F
-----
Y
Q
F
L
A
V
A
LG--F
S
L
V
F
YPTAYYSAATGSFG
D
A
ISGIRY
P
I
D
S
I
R
F
D
-----
F
T
S
K
I
L
E
N
M
F
F
Y
G
------------
L
L
S
L
G
L
G
F
V
V
C
I
F
L
G
L
FQSK
P
F
K
L
Y
V
I
SV
P
A
-
S
L
V
-
V
I
L
G
L
I
L
L
F
FSQEPL
H
A
S
Y
L
M
V
V
-
F
P
V
F
L
L
L
L
V
T
N
---
I
K
S
Q
Q
R
G
R
-
S
A
R
RSRRET
P
V
S
L
W
-------------
S
R
F
FKG
N
L
Y
L
---
L
V
F
G
F
V
Y
L
L
S
-
V
P
F
L
M
K
F
V
LY---PV
P
Y
Q
E
R
N
R
L
A
D
L
V
----
K
EETN----------T---------E
D
A
I
Y
AW-----DD-
T
A
T
L
Y
R
--
K
SERL
S
P
S
A
-
I
-LS---P----LHY---T-A-
T
E
E
-----------
N
R
-------
N
K
L
L
-
N
D
L
K
EKQ-----P
K
V
I
V
V
-ND
K
V
V
V
W
S
E
V
E
T
L
L
K
E
N
Y
Q
Q
V
KT-----------D
Y
S
E
F
K
V
Y
K
IK----------------------------------------------------------------------------------------------------------------------------------
26
Fugue
76.08
16%
-40
- C4 -
-
3SAM
4
D13_VACCW
A:
[25-572]
----------------------------------A
M
N
N
T
I
I
N
S
L
I
S
I
K
R
S
N
V
F
A
V
D
S
Q
I
P
T
L
Y
M
P
Q
Y
I
S
L
S
G
V
M
T
N
D
N
Q
A
I
A
S
F
E
I
R
D
Q
Y
I
T
----------------------
A
L
N
----
H
L
-
V
--
L
-
S
L
---
E
---
L
P
E
V
K
G
M
G
R
F
G
Y
V
P
Y
V
G
Y
K
C
I
N
H
V
S
--
I
S
-----
S
C
N
G
-------------------
V
I
----
W
-
E
I
E
-----
G
-
E
E
L
Y
N
N
C
I
NN
T
I
A
L
K
H
S
G
Y
S
S
E
L
N
D
I
S
I
G
L
T
P
N
D
T
I
K
E
P
S
T
V
Y
V
Y
I
K
T
P
-
F
--
D
--
V
E
--
D
--
T
F
-----
S
S
--
L
KLSD
S
K
I
T
V
T
V
T
F
N
P
V
S
D
I
V
----
I
R
-----------------------------
D
S
S
F
D
F
E
-----
T
F
N
K
E
--
F
V
Y
V
P
E
L
S
F
I
G
Y
M
V
K
N
V
Q
I
K
P
S
F
I
E
K
P
-
R
R
V
I
G
QINQP
T
-----
A
T
V
T
E
V
H
A
A
--
T
S
L
S
V
Y
T
K
P
Y
Y
G
N
T
D
N
K
F
I
-
S
Y
P
G
Y
S
Q
D
E
K
D
Y
I
D
A
-----
Y
V
S
R
L
L
D
D
L
V
I
V
S
DGPPTGYPES
A
E
I
V
E
V
P
E
D
G
I
V
S
I
-----
Q
D
A
D
V
Y
V
K
I
D
N
V
P
D
-
N
M
S
-
V
Y
L
H
T
N
L
L
M
F
G
T
R
K
N
S
F
I
Y
N
I
S
K
K
F
S
A
I
T
G
T
Y
S
D
A
TKR
T
I
F
A
H
I
S
H
-
S
I
N
I
I
D
T
S
I
P
V
S
L
W
T
SQRNVYNGDNRS
A
E
S
K
A
K
D
L
F
I
NDP
F
I
K
G
I
D
F
K
N
K
-
T
D
I
I
S
R
L
E
V
R
FGN
D
V
L
Y
S
E
N
G
P
I
S
R
I
Y
----
N
E
L
L
T
--------------------------------
K
S
-
N
N
G
T
R
T
--
L
T
F
N
F
T
P
K
I
-
F
-
F
R
---
P
----
T
T
I
---
T
-
A
N
V
S
R
-----------
G
K
-------
D
K
L
S
-
V
R
V
V
Y
S
T
M
G
VNH
P
I
Y
Y
V
Q
-
K
Q
L
V
V
V
C
N
D
L
Y
K
V
S
Y
D
Q
--------------------
G
V
S
I
T
K
I
M
----------------------------------------------------------------------------------------------------------------------------------
29
Fugue
64.85
18%
-36
- C3 -
-
1ZR6
3
?
A:
[3-481]
-----------------------------------
E
A
E
F
N
S
I
N
A
C
L
A
----
A
A
D
V
E
F
H
E
E
D
S
E
G
W
D
M
D
G
T
A
F
N
L
R
V
D
Y
D
P
A
A
I
A
I
P
R
S
----------------------------
T
E
---
D
I
-
A
--
A
-
A
V
---
Q
---
C
G
L
D
A
G
V
Q
---------
I
S
A
K
G
G
G
H
--
S
Y
-----
G
S
Y
G
FG
G
--------
E
D
G
H
L
M
L
E
L
D
----
R
-
M
Y
R
---------
V
S
V
D
D
---
N
N
V
A
T
I
Q
G
G
A
R
L
G
Y
T
A
L
E
L
L
D
Q
G
N
R
A
L
S
H
G
T
C
P
A
V
G
V
G
G
-
H
--
V
--
L
G
--
G
--
G
Y
G
FATH
T
H
--
G
------
L
T
L
D
W
L
I
G
A
T
V
V
L
A
DA
S
I
V
H
V
S
--------
E
T
-----------
E
----
N
A
D
L
F
W
A
L
R
G
GGG
G
F
A
I
V
S
E
F
E
F
N
T
F
E
A
P
E
I
I
T
T
Y
Q
V
T
T
T
W
N
R
K
Q
H
V
-
A
G
L
K
A
-----
L
-----
Q
D
W
A
Q
N
T
M
P
RE
L
S
M
R
L
E
I
N
A
N
A
L
N
W
E
G
N
F
F
G
N
A
K
D
L
K
K
I
L
Q
P
I
M
K
K
A
GGKS
T
I
S
K
L
V
E
T
D
W
Y
G
Q
------------
I
N
T
Y
L
Y
G
A
D
L
N
I
T
Y
N
Y
D
V
H
E
Y
F
Y
A
N
S
L
T
A
P
R
L
S
D
E
-
A
I
Q
A
F
V
D
Y
K
F
D
N
S
S
V
R
P
G
R
G
W
W
I
-
Q
W
D
F
H
G
G
K
N
S
A
---
L
A
A
V
S
N
D
E
-
T
A
Y
A
H
R
D
Q
----
L
W
-------------
L
W
Q
F
Y
D
S
I
Y
--------------------
D
Y
E
N
N
---
T
S
P
Y
P
E
S
G
F
------------
E
F
----------
M
---------
Q
G
F
V
A
T
I
-----
E
D
-
T
L
P
E
D
R
--
K
G
K
Y
F
N
Y
A
D
-
T
-----------------
T
-
L
-
T
K
E
-----------
E
A
-------
Q
K
L
Y
W
R
G
N
L
E
K
L
-----
Q
A
I
K
A
K
-
Y
D
P
E
D
V
F
G
N
V
V
S
V
E
P
I
A
Y
-------------------------------------------------------------------------------------------------------------------------------------------------------------
24
Fugue
52.64
11%
-80
- C6 -
-
4A01
9
AVP_VIGRR
A:
[2-766]
GAAILP
D
L
G
T
E
I
L
I
P
V
C
A
V
I
G
I
A
F
A
L
F
Q
W
L
L
V
S
K
V
K
L
S
A
V
D
H
N
V
V
V
K
----
C
A
E
I
Q
N
A
I
S
E
G
A
T
S
F
L
F
T
E
Y
K
Y
V
G
I
F
M
V
A
F
A
I
L
I
F
L
F
L
G
S
V
EGFSTSPQACSYDKT
K
T
C
K
P
A
L
A
T
A
I
---
F
S
-
T
--
V
-
S
F
---
L
---
L
G
G
V
T
S
L
V
S
G
F
----
L
G
M
K
I
A
T
Y
A
N
--
A
R
-----
T
T
L
E
--
A
--------
R
K
G
V
G
K
A
F
I
T
----
A
-
F
R
S
-----
G
-
A
V
M
G
F
L
L
---
A
A
N
G
L
L
V
L
Y
I
A
I
N
L
F
K
I
Y
Y
G
D
D
W
G
G
L
F
E
A
I
T
G
Y
G
L
G
G
S
S
-
M
--
A
--
L
F
--
G
--
R
V
-----
G
G
--
G
------
I
Y
T
K
A
A
D
V
G
A
D
L
V
G
----
K
V
E
R
NIPEDDPR
N
P
-----------
A
----
V
I
A
D
N
V
G
D
-----
N
V
G
D
I
A
G
M
G
S
D
L
F
G
S
Y
A
E
S
S
C
A
A
L
V
V
A
S
I
S
S
F
G
L
-
N
H
E
L
T
-----
A
-----
M
L
Y
P
L
I
V
S
S
--
V
G
I
L
V
C
L
L
T
T
L
F
A
T
D
F
F
E
I
K
A
V
K
E
I
E
P
A
L
K
K
Q
L
V
I
-----
S
T
V
L
M
T
I
G
V
A
V
V
S
------------
F
V
A
L
P
T
S
F
T
I
F
N
F
G
V
Q
K
D
V
K
S
W
Q
L
F
L
C
V
A
V
G
-
L
W
A
G
L
I
I
G
F
V
T
E
Y
Y
T
S
N
A
-
Y
S
P
V
Q
D
V
A
-
D
S
C
R
T
G
A
A
T
N
V
---
I
F
G
L
A
L
G
Y
K
S
V
I
I
P
I
F
A
I
A
I
S
I
F
-------------
V
S
F
T
F
A
A
M
Y
G
---
I
A
V
A
A
L
G
M
L
S
T
I
A
T
G
L
A
I
D
A
Y
---
G
P
I
S
D
N
A
G
G
I
A
E
M
A
GMS-
H
R
I
R
E
----------
R
---------
T
D
A
L
D
A
A
-----
G
N
-
T
T
A
A
I
G
--
K
G
F
A
I
G
S
A
A
-
L
-
V
S
---
L
----
A
L
F
---
G
-
A
-
F
V
S
R
A
SITTVDVLT
P
K
-------
V
F
I
G
-
L
I
V
G
A
M
L
-----
P
Y
W
F
S
A
-
M
T
M
K
S
V
G
S
A
A
L
K
M
V
E
E
V
R
R
Q
F
N
T
IPGLMEGTAKP
D
Y
A
T
C
V
K
I
S
T
D
A
S
I
K
E
M
I
P
P
G
A
L
V
M
L
T
P
L
V
V
G
I
L
FG
V
E
T
L
S
G
V
L
A
G
S
L
V
S
G
V
Q
I
A
I
S
A
S
N
T
G
G
A
W
D
N
A
K
K
Y
I
E
A
GAS
E
H
A
R
S
L
G
PKGS
D
C
H
K
A
A
V
I
G
D
T
I
G
DPLKDT
S
G
P
S
L
N
I
L
I
K
L
M
A
V
E
S
L
V
F
A
P
F
F
A
T
HGG
L
L
F
K
I
F
8
HHSearch
45.48
10%
-146
- C5 -
-
5F15
10
?
A:
[37-226]
-----------------------------------------------------------------------------------
F
V
A
V
A
L
V
V
W
----------------------
F
V
S
L
---
D
M
R
H
--
L
-
V
----------
G
P
D
E
G
R
Y
A
E
----
I
S
R
E
M
F
A
S
G
D
--
W
V
T
I
R
Y
N
A
L
K
Y
--
F
--------
E
K
P
P
F
H
M
W
V
T
V
V
G
-
Y
E
L
F
G
-----
L
G
E
W
Q
A
R
L
A
---
V
A
L
S
G
L
L
G
I
G
V
S
M
M
A
A
R
R
W
F
G
A
R
-
A
A
-
A
F
T
G
L
A
L
L
A
A
P
M
-
W
S
V
A
--
A
H
--
F
--
N
T
-----
L
D
--
M
------
T
L
A
G
V
M
S
C
V
L
A
F
M
L
----
M
G
Q
H
--------
P
D
-----------
A
S
V
A
A
R
R
G
W
M
V
A
C
-----
W
A
A
M
G
V
A
I
L
T
K
G
L
V
G
I
A
L
-
P
G
L
V
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
45.33
34%
-140
- C5 -
-
1TUO
-
?
A:
[254-335]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
V
-----
G
V
V
L
P
G
G
V
F
F
N
P
H
Q
V
L
-----
T
T
L
A
L
Y
R
F
R
K
G
H
R
G
R
A
V
K
N
-----
F
AVTW
L
L
D
R
L
G
E
R
L
G
--
F
G
V
T
T
T
P
V
G
F
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
45.25
10%
-147
- C5 -
-
5EZM
13
?
A:
[37-231]
-----------------------------------------------------------------------------------
F
V
A
V
A
L
V
V
W
----------------------
F
V
S
L
---
D
M
R
H
--
L
-
V
----------
G
P
D
E
G
R
Y
A
E
----
I
S
R
E
M
F
A
S
G
D
--
W
V
T
I
R
Y
N
A
L
K
Y
--
F
--------
E
K
P
P
F
H
M
W
V
T
V
V
G
-
Y
E
L
F
G
-----
L
G
E
W
Q
A
R
L
A
---
V
A
L
S
G
L
L
G
I
G
V
S
M
M
A
A
R
R
W
F
G
A
R
-
A
A
-
A
F
T
G
L
A
L
L
A
A
P
M
-
W
S
V
A
--
A
H
--
F
--
N
T
-----
L
D
--
M
------
T
L
A
G
V
M
S
C
V
L
A
F
M
L
----
M
G
Q
H
--------
P
D
-----------
A
S
V
A
A
R
R
G
W
M
V
A
C
-----
W
A
A
M
G
V
A
I
L
T
K
G
L
V
G
I
A
L
-
P
G
L
V
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
44.93
10%
-110
- C5 -
-
3WAK
-
?
A:
[14-229]
-----------------------------------------------------------------------------
L
S
V
L
V
I
A
A
L
I
S
V
K
L
R
----------------------
I
L
N
P
---
W
N
-
S
--
V
-
F
T
WTV
R
---
L
G
G
N
D
P
W
Y
Y
Y
R
----
L
I
E
N
T
I
H
N
F
P
HR
I
W
-----
F
D
P
F
--
T
YYP
Y
G
S
Y
T
H
F
G
P
F
L
V
Y
L
G
S
I
A
G
I
-
I
F
S
ATSG
E
S
L
R
A
V
L
A
F
I
---
P
A
I
G
G
V
L
A
I
L
P
V
Y
L
L
T
R
E
V
F
D
K
-
R
A
A
-
V
I
A
A
F
L
I
A
I
V
P
G
Q
F
--
L
Q
R
S
I
--
L
--
G
F
-----
N
D
H
H
I
------
W
E
A
F
W
Q
V
S
A
L
G
T
F
L
----
L
A
Y
N
--------
R
W
KGHDLSHNLT
A
R
----
Q
M
A
Y
P
V
I
A
-----
G
I
T
I
G
L
Y
V
L
S
W
G
A
G
F
I
I
A
-
P
I
I
L
A
F
M
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
44.71
10%
-118
- C5 -
-
3WAJ
-
?
A:
[15-286]
------------------------------------------------------------------------------
S
V
L
V
I
A
A
L
I
S
V
K
L
R
----------------------
I
L
N
P
---
W
N
-
S
--
V
-
F
T
WTV
R
---
L
G
G
N
D
P
W
Y
Y
Y
R
----
L
I
E
N
T
I
H
N
F
P
HR
I
W
-----
F
D
P
F
--
T
YYP
Y
G
S
Y
T
H
F
G
P
F
L
V
Y
L
G
S
I
A
G
I
-
I
F
S
ATSG
E
S
L
R
A
V
L
A
F
I
---
P
A
I
G
G
V
L
A
I
L
P
V
Y
L
L
T
R
E
V
F
D
K
-
R
A
A
-
V
I
A
A
F
L
I
A
I
V
P
G
Q
F
--
L
Q
R
S
I
--
L
--
G
F
-----
N
D
H
H
I
------
W
E
A
F
W
Q
V
S
A
L
G
T
F
L
----
L
A
Y
N
--------
R
W
KGHDLT
A
----
R
----
Q
M
A
Y
P
V
I
A
-----
G
I
T
I
G
L
Y
V
L
S
W
G
A
G
F
I
I
A
-
P
I
I
L
A
F
M
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
41.49
23%
-37
- C7 -
-
5H8C
1
XPD_SULAC
A:
[118-268]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
S
P
L
S
L
V
-------------
K
K
L
K
K
D
G
L
Q
D
---
K
F
C
P
Y
Y
S
L
L
N
-
S
L
Y
K
A
D
V
I
A
L
---
T
Y
P
Y
F
F
I
D
R
Y
R
E
F
I
DIDL
R
E
Y
M
I
----------
V
---------
I
D
E
A
H
N
L
-----
D
K
-
V
N
E
L
E
E
--
R
S
--
L
S
E
I
T
-
I
-
Q
M
---
A
----
I
K
Q
---
S
-
K
-
S
E
E
-----------
S
R
R
I
L
----
S
K
L
L
-
N
Q
L
R
E
---------
V
V
L
P
-
D
E
K
Y
I
K
V
E
N
V
P
K
L
S
K
E
E
L
E
I
L
A
D
-----------
D
Y
E
D
I
R
K
D
S
L
K
----------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
41.33
24%
-61
- C5 -
-
1E6V
-
?
B:
[171-296]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
F
G
G
N
V
----------
A
S
M
L
D
-
V
P
M
K
Q
E
G
V
G
Y
---
A
L
R
N
I
M
V
N
H
I
V
A
A
T
----
R
K
N
T
M
----------
Q
---------
A
V
C
L
A
A
T
-----
L
Q
-
Q
T
A
M
F
E
--
M
G
D
A
L
G
P
F
E
-
R
-
L
H
---
L
----
L
G
Y
---
A
-
Y
-
Q
G
L
-----------
N
A
-------
D
N
M
V
-
Y
D
I
V
K
K
H
-----
G
K
E
G
T
V
-
G
--
T
V
V
R
E
V
V
E
R
A
L
E
D
G
V
I
E
V
K
E
-----------
E
L
P
S
F
K
V
Y
K
------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
40.80
23%
-35
* C7 *
-
3CRV
2
XPD_SULAC
A:
[118-264]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
S
P
L
S
L
V
-------------
K
K
L
K
K
D
G
L
Q
D
---
K
F
C
P
Y
Y
S
L
L
N
-
S
L
Y
K
A
D
V
I
A
L
---
T
Y
P
Y
F
F
I
D
R
Y
R
E
F
I
DIDL
R
E
Y
M
I
----------
V
---------
I
D
E
A
H
N
L
-----
D
K
-
V
N
E
L
E
E
--
R
S
--
L
S
E
I
T
-
I
-
Q
M
---
A
----
I
K
Q
---
S
-
K
-
S
E
E
-----------
S
R
R
I
L
----
S
K
L
L
-
N
Q
L
R
E
---------
V
V
L
P
-
D
E
K
Y
I
K
V
E
N
V
P
K
L
S
K
E
E
L
E
I
L
A
D
-----------
D
Y
E
D
I
R
K
D
S
L
K
----------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
37.85
11%
31
- C5 -
-
3VGP
-
?
A:
[432-522]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
E
D
W
K
E
A
L
E
W
M
----
R
T
S
L
E
----------
E
QNYNPYEKP
E
Y
S
V
M
S
W
-----
W
D
Y
G
N
W
I
L
Y
--
V
S
K
K
A
V
V
A
N
N
F
-
Q
A
--------
G
A
V
D
A
A
K
F
F
-
T
A
K
-----------
S
E
-------
D
E
A
I
-
K
I
A
K
K
R
G
-----
V
R
Y
V
V
T
-
A
D
E
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
36.75
9%
34
- C5 -
-
3VU0
1
?
B:
[4-94]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
M
D
W
K
E
A
L
N
W
M
----
K
E
N
L
E
AQDYLKAYEK
P
---------
D
Y
A
V
L
S
W
-----
W
D
Y
G
N
W
I
L
Y
--
V
A
K
K
A
V
V
C
N
N
F
-
Q
A
G
A
-
D
----
D
A
A
---
K
F
F
-
T
A
Q
-----------
S
E
-------
E
E
A
M
-
K
I
V
E
K
R
K
-----
V
R
Y
V
V
T
-
V
E
E
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
35.11
7%
-113
- C5 -
-
3RCE
-
PGLB_CAMLR
A:
[18-226]
------------------------------------------------------------------------------
I
L
I
L
I
A
F
A
F
S
V
L
C
R
----------------------
L
Y
W
V
AWA
S
E
-
F
YE
F
F
F
N
---
D
Q
L
M
I
T
T
N
D
G
Y
A
F
A
E
----
G
A
R
D
M
I
A
G
F
---
H
Q
-----
P
N
D
L
--
S
--------
Y
F
G
S
S
L
S
T
L
T
Y
W
L
Y
S
-
I
L
P
F----
S
F
E
S
I
I
L
Y
M
---
S
T
F
F
A
S
L
I
V
V
P
I
I
L
I
A
R
E
Y
K
L
T
-
T
Y
G
-
F
I
A
A
L
L
G
S
I
A
N
S
-
Y
--
Y
--
N
R
T
M
S
GY
Y
D
-----
T
D
--
M
------
L
V
L
V
L
P
M
L
I
L
L
T
F
I
----
R
L
T
I
--------
N
K
----------------
D
I
F
T
L
L
L
S
-----
P
I
F
I
M
I
Y
L
W
W
Y
P
S
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
HHSearch
34.81
10%
-5
- C5 -
-
2ZAI
-
?
B:
[18-101]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
S
G
W
E
D
A
L
K
W
L
----
R
E
N
T
P
----------
E
---------
Y
S
T
A
T
S
W
-----
W
D
Y
G
Y
W
I
E
S
S
L
L
G
---------H
A
R
D
R
D
H
----
I
L
A
---
L
-
F
-
L
A
R
-----------
D
G
-------
N
I
S
E
-
V
D
F
E
S
W
E
-----
L
N
Y
F
L
V
-
Y
L
N
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
Fugue
32.48
9%
-4
- C5 -
-
2LW1
-
UUP_ECOLI
A:
[551-635]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
A
E
T
V
K
R
S
S
S
----
K
L
S
Y
K
----------
L
---------
Q
R
E
L
E
Q
L
-----
P
Q
-
L
L
E
D
L
E
--
A
K
L
E
A
L
Q
T
Q
-
V
-
A
D
---
A
----
S
F
F
---
S
-
Q
-
P
H
E
-----------
Q
T
-------
Q
K
V
L
-
A
D
M
A
A
A
E
-----
Q
E
L
E
Q
A
-
F
E
R
---
W
E
Y
L
E
A
L
K
N
G
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------
16
HHSearch
31.43
8%
40
- C5 -
-
3VU1
-
?
B:
[10-94]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
T
G
W
E
Q
A
L
K
W
L
----
R
S
N
T
S
----------
K
---------
Y
A
T
A
T
S
W
-----
W
D
Y
G
Y
W
I
E
S
SL
L
G
N
R
R
A
S
A
D
G
G
-
H
A
---
R
DR
D
H
I
L
A
---
L
-
F
-
L
A
R
-----------
D
G
-------
N
I
S
E
-
V
D
F
E
S
W
E
-----
L
N
Y
F
I
I
-
Y
L
N
D
W
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
31.15
25%
-211
- C5 -
-
3H1D
-
A:
[84-150]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
G
Q
D
A
G
G
L
L
R
E
W
Y
M
I
I
S
R
-
E
--
M
--
F
N
--
P
--
M
Y
-----
A
L
--
F
------
R
T
S
P
G
D
R
V
T
Y
T
I
N
P
----
S
------------------------
N
----
H
L
S
Y
F
K
F
V
-----
G
R
I
V
A
K
A
V
Y
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
Fugue
28.96
7%
20
- C6 -
-
2NO2
-
HIP1_HUMAN
A:
[480-581]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
S
H
A
D
L
L
R
K
N
A
E
----
V
T
K
Q
V
----------
S
---------
M
A
R
Q
A
Q
V
-----
D
L
-
E
R
E
K
K
E
--
L
E
D
S
L
E
R
I
S
-
D
-
Q
G
---
Q
----
R
K
T
---
Q
-
E
-
Q
L
E
-----------
V
L
-------
E
S
L
K
-
Q
E
L
A
T
S
Q
-----
R
E
L
Q
V
L
-
Q
G
S
L
E
T
S
A
Q
S
E
A
N
W
A
A
E
F
A
E
L
E
K
-----------
E
R
D
S
L
V
---------------------------------------------------------------------------------------------------------------------------------------
22
Fugue
28.17
9%
72
- C5 -
-
3WHJ
-
PSMD9_YEAST
A:
[3-119]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
E
E
E
E
L
S
K
L
L
----
A
N
V
K
I
----------
D
---------
P
S
L
T
S
R
I
S
Q
I
DS
F
K
-
L
S
E
L
M
V
--
L
K
T
D
I
E
T
Q
L
-
E
-
A
Y
---
F
----
S
V
L
---
E
-
Q
-
Q
G
I
-----------
G
M
DSAYPRS
D
V
D
V
-
L
Q
V
T
M
I
R
-----
K
N
V
N
M
L
K
N
D
L
N
H
L
L
Q
R
S
H
V
L
L
N
Q
H
F
D
N
M
N
V
-----------
K
S
N
Q
-----------------------------------------------------------------------------------------------------------------------------------------