@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : spr0247: (2017-12-18 )
MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISSDESTPTTNEPNNRNTTTLAQPLTDTAADSGKNESDISSPRNANASLEKTEEKPATEPTTSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDDVEKPSENWPNGALSFKDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVEKLVPKMNEAWLDQDYKVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQWPDGTDFTATGKYGRYIDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQIFLKDDDESIYTNPYYVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHLGNKVTITDVAIDEAGKKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWHLKDETYSYDGKLGADLKEEGKQVDLTLWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDSTNKLGITDFTGYYYQYQIERQGKTVLALDPYAKSLAAWNSDDAKIDDAHKVAKAAFVDPAKLGPQDLTYGKIHNFKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDYLKDLGVTHIQLLPVLSYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSDPKNPEKRIAEFKNLINEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFMDADGTPRTSFGGGRLGTTHHMTKRLLVDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARALNPNLIMLGEGWRTYAGDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPAFITGGKRDVNTIFKNLIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKAENYAEIHRRLRLGNLMVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHLLRDKDGNPFDYPYFIHDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQSTDAFRLKSLQDIKDRVHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKAREFNLGTAFAHLRNAEVLADENQAGSVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTSHESTAEEKPDSTPSKPEHQDPAPEARPDSTKPDAKVADAENKPSQATADSQAEQPAQEAQASSVKEAVQNESVENSSKKNIPATPDRQAELPNTGIKNENKLLFAGISLLALLGLGFLLKNKKEN
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230....-------..-------.240.......250..-----.....260..-.....270.......280.......290.......300.......310..-.-....320.......330...----.----...340.......350..--.....360.....----..370.....--.-.380.....-------------------...--.390-----------------------.........400---..-.....410.-..-----.-----...420....-----...430-..---..-.....440.......450.......460.......470-........-480-.-........490.......500.......510.-------------.---------.------....520.......530...-----..-.-.-----540-....-------....-.550--.......560--.....----..570.......580..---.-....590...--------....600----------..-------.-------.--.-----------...610.......620.......630.....-------------------.---------------------------------------------------.640.......650.......660.......---670.......680.....-..690.......700-..--.---.------.------...710.......720........-730.-.......740.......750.......760.......770.--------...--.....780-..--------------------------------------.--------.....790.......800.......810.......820.......----830.....------.------.840......---------------.850------------..-------------------...----...--------------------.-------------------------860-----------------------..-----..--....-----.870.......880.......890.....---------------------..------------------------900.......910.......920.......930.......940.......950.......960.......970.......980.......990.------------.------------..---------------.----------------..1000......1010......1020.....-.1030......-1040-.........1050...------------.----.----.1060......1070......1080....---..1090.....-.1100--..-----------......1110......1120......1130......1140......1150......1160......1170......1180......1190......1200......1210......1220......1230......1240......1250...
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MRKTPSH
T
E
K
K
M
V
Y
S
I
R
S
LKNGTG
S
V
L
I
G
A
S
L
V
L
L
A
MATPTISSDESTPTTNEPNNRNT
T
T
L
AQPLTDTAADSGKNESDISSPRNANASLEKTEEKPATEPTTSTSPVTTETKAEEPIED
N
Y
F
R
I
H
V
K
KLPEENKDAQGLWTWDDVEKPSENWPNGALSFKDAKKDDY
G
Y
Y
L
D
V
K
L
KGEQ
A
K
K
I
S
F
L
I
NNTAGKNLTG
D
K
S
V
E
K
L
V
P
K
M
N
E
A
W
LDQD
Y
K
V
F
S
YEPQPA
G
T
V
R
V
N
Y
Y
-------
R
T-------DGNYDK
K
S
L
W
Y
W
GDVK-----NPSSAQWPDG-TDFTATGKY
G
R
Y
I
DI
P
L
N
E
A
A
R
E
F
G
F
L
L
LDESKQGD
D
V
K
I
R
KENYKFTDL-K-NH
S
Q
I
F
L
KDDDESIYTN
P
Y
Y
----
V
----
H
D
I
R
MTGAQHVG
T
S
S
I
E
S
--
S
F
S
T
L
VGA
K
K
E
D
I
----
L
KHS
N
I
T
N
HL--G-N
K
--
V
T
I
T
D
-------------------
V
A
I--DE-------------------------AG
K
K
V
T
YSGDFS---DT-KH
P
Y
T
V
S
YN-SD-----
Q
-----
F
T
TK
T
S
W
H
LK-----DETY---SY---DG-KLGA
D
L
K
EEG
K
Q
V
D
L
T
L
WSPSA
D
K
V
S
V
V
V
Y
DKNDPD
K
--
V
V
G
T
V
A
LE-K---G-ERG
T
W
K
Q
T
LDSTNKLGITDFT
G
Y
Y
Y
Q
Y
Q
I
ERQ-------------G---------
K
------
T
V
L
A
L
D
P
Y
A
K
S
L
AAWNSDDA-----KI-
D
-
D
-----
A
---
H
K
V
A
-------
K
A
AF-V
D
P
A--KLGPQDLTYG--KIHNF----KTRE
D
A
V
I
Y
E
A
H
V
R
DFT---S-D
P
A
I
A
K
D
L
TK--------PF
G
T
F
E
-----------
A
F
-------
I
-------
E
--
K
-----------
L
D
Y
L
K
DLGV
T
H
I
Q
L
L
P
V
L
S
Y
Y
F
V
N
E
LK
N
H
E
R
-------------------
L
---------------------------------------------------
S
D
Y
ASSNSNYNWGYDPQ
N
Y
F
S
L
TGMYSSDPK---
N
P
E
K
R
I
A
E
F
K
N
L
I
N
E
I
H
K
-
R
G
M
G
A
I
L
D
V
V
YNHT--A
K
--
V
---
D
------
I
------FEDLEPN
Y
Y
H
F
MDA-DGTPRTSFG-GG-R-LG
T
T
H
H
M
T
K
R
L
L
V
D
S
I
K
Y
L
V
D
TYKVD
G
F
R
F
DMMGDH
D
A
--
A
--------
S
I
E
--
E
A
Y
K
A
A
R--AL--------------------------------------N--------P
N
L
I
M
LGEG
W
R
TYAGDENMPTKAA
D
Q
D
W
M
KHT
D
T
V
A
V
F
S
D
D
I
R
N
N
----
L
KSGYPNE------G------Q
P
A
F
I
TGGK
R
---------------
D
V
--------------
N
T
-------------------
I
F
K
----
N
LI--------------------A-------------------------Q-------------------------PT-----NF--EADS-----P
G
D
V
I
Q
Y
I
A
AHDNL
T
L
F
D
I
I
A
Q
S
I
KKDP
S
---------------------
K
A
------------------------
E
N
Y
A
E
I
H
R
R
LRLG
N
L
M
V
L
TAQGTPFIHS
G
Q
EYGRTKQFRDPAYKTPVAEDKVPN
K
S
HLLRDKDGNPFDY
P
Y
F
I
HDSYDSSDAVNKFDWTKATDG------------K------------AY---------------
P
----------------
E
NV
K
S
R
D
Y
M
K
G
L
I
A
L
RQST
D
A
F
R
L
K
S
L
Q
D
I
K-DR
V
H
L
I
T
VPGQ-N----GVEKE
D
V
V
I
G
Y
Q
I
TAP------------N----G----
D
I
Y
A
V
F
VNADEK
A
R
EFNL
G
T
A
F
A
H
LRN
A
E
---
V
L
ADENQAGSV-GIA----NP-----------KGL
E
W
T
E
KG
L
K
L
N
A
L
T
A
T
V
L
R
VSQNGTSHESTAEEKPDSTPSKPEHQDPAPEARPDSTKPDAKVADAENKPSQATAD
S
Q
AEQ
P
A
Q
E
A
Q
A
S
S
V
K
E
A
V
QNESVENSSKKNIPATPDRQAELPNTGIKNEN
K
L
L
F
A
G
I
S
L
L
A
L
L
G
L
G
F
L
LKNKKEN
1
PsiBlast_PDB
85.70
99%
-44
- C2 -
-
2YA0
4
?
A:
[1-714]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
W
R
L
K
-----
D
E
T
Y
---
S
Y
---
D
G
-
K
L
G
A
D
L
K
E
E
G
K
Q
V
D
L
T
L
W
S
P
S
A
D
K
V
S
V
V
V
Y
D
K
N
D
P
D
K
--
V
V
G
T
V
A
L
E
-
K
---
G
-
E
R
G
T
W
K
Q
T
L
D
S
T
N
K
L
G
I
T
D
F
T
G
Y
Y
Y
Q
Y
Q
I
E
R
Q
-------------
G
---------
K
------
T
V
L
A
L
D
P
Y
A
K
S
L
A
A
W
N
S
D
D
S
-----
K
I
-
D
-
D
-----
A
---
H
K
V
A
-------
K
A
A
F
-
V
D
P
A
--
K
L
G
P
Q
D
L
T
Y
G
--
K
I
H
N
F
----
K
T
R
E
D
A
V
I
Y
E
A
H
V
R
D
F
T
---
S
-
D
P
A
I
A
K
D
L
T
K
--------
P
F
G
T
F
E
-----------
A
F
-------
I
-------
E
--
K
-----------
L
D
Y
L
K
D
L
G
V
T
H
I
Q
L
L
P
V
L
S
Y
Y
F
V
N
E
L
K
N
H
E
R
-------------------
L
---------------------------------------------------
S
D
Y
A
S
S
N
S
N
Y
N
W
G
Y
D
P
Q
N
Y
F
S
L
T
G
M
Y
S
S
D
P
K
---
N
P
E
K
R
I
A
E
F
K
N
L
I
N
E
I
H
K
-
R
G
M
G
A
I
L
D
V
V
Y
N
H
T
--
A
K
--
V
---
D
------
L
------
F
E
D
L
E
P
N
Y
Y
H
F
M
D
A
-
D
G
T
P
R
T
S
F
G
-
G
G
-
R
-
L
G
T
T
H
H
M
T
K
R
L
L
I
D
S
I
K
Y
L
V
D
T
Y
K
V
D
G
F
R
F
D
M
M
G
D
H
D
A
--
A
--------
S
I
E
--
E
A
Y
K
A
A
R
--
A
L
--------------------------------------
N
--------
P
N
L
I
M
L
G
E
G
W
R
T
Y
A
G
D
E
N
M
P
T
K
A
A
D
Q
D
W
M
K
H
T
D
T
V
A
V
F
S
D
D
I
R
N
N
----
L
K
S
G
Y
P
N
E
------
G
------
Q
P
A
F
I
T
G
G
K
R
---------------
D
V
--------------
N
T
-------------------
I
F
K
----
N
L
I
--------------------
A
-------------------------
Q
-------------------------
P
T
-----
N
F
--
E
A
D
S
-----
P
G
D
V
I
Q
Y
I
A
A
H
D
N
L
T
L
F
D
I
I
A
Q
S
I
K
K
D
P
S
---------------------
K
A
------------------------
E
N
Y
A
E
I
H
R
R
L
R
L
G
N
L
M
V
L
T
A
Q
G
T
P
F
I
H
S
G
Q
E
Y
G
R
T
K
Q
F
R
N
P
A
Y
R
T
P
V
A
E
D
K
V
P
N
K
S
H
L
L
R
D
K
D
G
N
P
F
D
Y
P
Y
F
I
H
D
S
Y
D
S
S
D
A
V
N
K
F
D
W
T
K
A
T
D
G
------------
K
------------
A
Y
---------------
P
----------------
E
N
V
K
S
R
D
Y
M
K
G
L
I
A
L
R
Q
S
T
D
A
F
R
L
K
S
L
Q
D
I
K
-
D
R
V
H
L
I
T
V
P
G
Q
-
N
----
G
V
E
K
E
D
V
V
I
G
Y
Q
I
T
A
P
------------
N
----
G
----
D
I
Y
A
V
F
V
N
A
D
E
K
A
R
E
F
N
L
G
T
A
F
A
H
L
R
N
A
E
---
V
L
A
D
E
N
Q
A
G
P
V
-
G
I
A
----
N
P
-----------
K
G
L
E
W
T
E
K
G
L
K
L
N
A
L
T
A
T
V
L
R
V
S
Q
N
G
T
S
H
E
S
T
-------------------------------------------------------------------------------------------------------------------------
78
HHSearch
85.34
99%
-44
- C2 -
-
2YA0
4
?
A:
[2-711]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
R
L
K
-----
D
E
T
Y
---
S
Y
---
D
G
-
K
L
G
A
D
L
K
E
E
G
K
Q
V
D
L
T
L
W
S
P
S
A
D
K
V
S
V
V
V
Y
D
K
N
D
P
D
K
--
V
V
G
T
V
A
L
E
-
K
---
G
-
E
R
G
T
W
K
Q
T
L
D
S
T
N
K
L
G
I
T
D
F
T
G
Y
Y
Y
Q
Y
Q
I
E
R
Q
-------------
G
---------
K
------
T
V
L
A
L
D
P
Y
A
K
S
L
A
A
W
N
S
D
D
S
-----
K
I
-
D
-
D
-----
A
---
H
K
V
A
-------
K
A
A
F
-
V
D
P
A
--
K
L
G
P
Q
D
L
T
Y
G
--
K
I
H
N
F
----
K
T
R
E
D
A
V
I
Y
E
A
H
V
R
D
F
T
---
S
-
D
P
A
I
A
K
D
L
T
K
--------
P
F
G
T
F
E
-----------
A
F
-------
I
-------
E
--
K
-----------
L
D
Y
L
K
D
L
G
V
T
H
I
Q
L
L
P
V
L
S
Y
Y
F
V
N
E
L
K
N
H
E
R
-------------------
L
---------------------------------------------------
S
D
Y
A
S
S
N
S
N
Y
N
W
G
Y
D
P
Q
N
Y
F
S
L
T
G
M
Y
S
S
D
P
K
---
N
P
E
K
R
I
A
E
F
K
N
L
I
N
E
I
H
K
-
R
G
M
G
A
I
L
D
V
V
Y
N
H
T
--
A
K
--
V
---
D
------
L
------
F
E
D
L
E
P
N
Y
Y
H
F
M
D
A
-
D
G
T
P
R
T
S
F
G
-
G
G
-
R
-
L
G
T
T
H
H
M
T
K
R
L
L
I
D
S
I
K
Y
L
V
D
T
Y
K
V
D
G
F
R
F
D
M
M
G
D
H
D
A
--
A
--------
S
I
E
--
E
A
Y
K
A
A
R
--
A
L
--------------------------------------
N
--------
P
N
L
I
M
L
G
E
G
W
R
T
Y
A
G
D
E
N
M
P
T
K
A
A
D
Q
D
W
M
K
H
T
D
T
V
A
V
F
S
D
D
I
R
N
N
----
L
K
S
G
Y
P
N
E
------
G
------
Q
P
A
F
I
T
G
G
K
R
---------------
D
V
--------------
N
T
-------------------
I
F
K
----
N
L
I
--------------------
A
-------------------------
Q
-------------------------
P
T
-----
N
F
--
E
A
D
S
-----
P
G
D
V
I
Q
Y
I
A
A
H
D
N
L
T
L
F
D
I
I
A
Q
S
I
K
K
D
P
S
---------------------
K
A
------------------------
E
N
Y
A
E
I
H
R
R
L
R
L
G
N
L
M
V
L
T
A
Q
G
T
P
F
I
H
S
G
Q
E
Y
G
R
T
K
Q
F
R
N
P
A
Y
R
T
P
V
A
E
D
K
V
P
N
K
S
H
L
L
R
D
K
D
G
N
P
F
D
Y
P
Y
F
I
H
D
S
Y
D
S
S
D
A
V
N
K
F
D
W
T
K
A
T
D
G
------------
K
------------
A
Y
---------------
P
----------------
E
N
V
K
S
R
D
Y
M
K
G
L
I
A
L
R
Q
S
T
D
A
F
R
L
K
S
L
Q
D
I
K
-
D
R
V
H
L
I
T
V
P
G
Q
-
N
----
G
V
E
K
E
D
V
V
I
G
Y
Q
I
T
A
P
------------
N
----
G
----
D
I
Y
A
V
F
V
N
A
D
E
K
A
R
E
F
N
L
G
T
A
F
A
H
L
R
N
A
E
---
V
L
A
D
E
N
Q
A
G
P
V
-
G
I
A
----
N
P
-----------
K
G
L
E
W
T
E
K
G
L
K
L
N
A
L
T
A
T
V
L
R
V
S
Q
N
G
T
S
H
----------------------------------------------------------------------------------------------------------------------------
79
HHSearch
85.22
99%
-48
- C2 -
-
2YA2
2
?
A:
[2-707]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
W
R
L
K
-----
D
E
T
Y
---
S
Y
---
D
G
-
K
L
G
A
D
L
K
E
E
G
K
Q
V
D
L
T
L
W
S
P
S
A
D
K
V
S
V
V
V
Y
D
K
N
D
P
D
K
--
V
V
G
T
V
A
L
E
-
K
---
G
-
E
R
G
T
W
K
Q
T
L
D
S
T
N
K
L
G
I
T
D
F
T
G
Y
Y
Y
Q
Y
Q
I
E
R
Q
-------------
G
---------
K
------
T
V
L
A
L
D
P
Y
A
K
S
L
A
A
W
N
S
D
D
S
-----
K
I
-
D
-
D
-----
A
---
H
K
V
A
-------
K
A
A
F
-
V
D
P
A
--
K
L
G
P
Q
D
L
T
Y
G
--
K
I
H
N
F
----
K
T
R
E
D
A
V
I
Y
E
A
H
V
R
D
F
T
---
S
-
D
P
A
I
A
K
D
L
T
K
--------
P
F
G
T
F
E
-----------
A
F
-------
I
-------
E
--
K
-----------
L
D
Y
L
K
D
L
G
V
T
H
I
Q
L
L
P
V
L
S
Y
Y
F
V
N
E
L
K
N
H
E
R
-------------------
L
---------------------------------------------------
S
D
Y
A
S
S
N
S
N
Y
N
W
G
Y
D
P
Q
N
Y
F
S
L
T
G
M
Y
S
S
D
P
K
---
N
P
E
K
R
I
A
E
F
K
N
L
I
N
E
I
H
K
-
R
G
M
G
A
I
L
D
V
V
Y
N
H
T
--
A
K
--
V
---
D
------
L
------
F
E
D
L
E
P
N
Y
Y
H
F
M
D
A
-
D
G
T
P
R
T
S
F
G
-
G
G
-
R
-
L
G
T
T
H
H
M
T
K
R
L
L
I
D
S
I
K
Y
L
V
D
T
Y
K
V
D
G
F
R
F
D
M
M
G
D
H
D
A
--
A
--------
S
I
E
--
E
A
Y
K
A
A
R
--
A
L
--------------------------------------
N
--------
P
N
L
I
M
L
G
E
G
W
R
T
Y
A
G
D
E
N
M
P
T
K
A
A
D
Q
D
W
M
K
H
T
D
T
V
A
V
F
S
D
D
I
R
N
N
----
L
K
S
G
Y
P
N
E
------
G
------
Q
P
A
F
I
T
G
G
K
R
---------------
D
V
--------------
N
T
-------------------
I
F
K
----
N
L
I
--------------------
A
-------------------------
Q
-------------------------
P
T
-----
N
F
--
E
A
D
S
-----
P
G
D
V
I
Q
Y
I
A
A
H
D
D
L
T
L
F
D
I
I
A
Q
S
I
K
K
D
P
S
---------------------
K
A
------------------------
E
N
Y
A
E
I
H
R
R
L
R
L
G
N
L
M
V
L
T
A
Q
G
T
P
F
I
H
S
G
Q
E
Y
G
R
T
K
Q
F
R
N
P
A
Y
R
T
P
V
A
E
D
K
V
P
N
K
S
H
L
L
R
D
K
D
G
N
P
F
D
Y
P
Y
F
I
H
D
S
Y
D
S
S
D
A
V
N
K
F
D
W
T
K
A
T
D
G
------------
K
------------
A
Y
---------------
P
----------------
E
N
V
K
S
R
D
Y
M
K
G
L
I
A
L
R
Q
S
T
D
A
F
R
L
K
S
L
Q
D
I
K
-
D
R
V
H
L
I
T
V
P
G
Q
-
N
----
G
V
E
K
E
D
V
V
I
G
Y
Q
I
T
A
P
------------
N
----
G
----
D
I
Y
A
V
F
V
N
A
D
E
K
A
R
E
F
N
L
G
T
A
F
A
H
L
R
N
A
E
---
V
L
A
D
E
N
Q
A
G
P
V
-
G
I
A
----
N
P
-----------
K
G
L
E
W
T
E
K
G
L
K
L
N
A
L
T
A
T
V
L
R
V
S
Q
---------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
84.87
98%
-47
- C2 -
-
2YA2
2
?
A:
[1-708]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
S
W
R
L
K
-----
D
E
T
Y
---
S
Y
---
D
G
-
K
L
G
A
D
L
K
E
E
G
K
Q
V
D
L
T
L
W
S
P
S
A
D
K
V
S
V
V
V
Y
D
K
N
D
P
D
K
--
V
V
G
T
V
A
L
E
-
K
---
G
-
E
R
G
T
W
K
Q
T
L
D
S
T
N
K
L
G
I
T
D
F
T
G
Y
Y
Y
Q
Y
Q
I
E
R
Q
-------------
G
---------
K
------
T
V
L
A
L
D
P
Y
A
K
S
L
A
A
W
N
S
D
D
S
-----
K
I
-
D
-
D
-----
A
---
H
K
V
A
-------
K
A
A
F
-
V
D
P
A
--
K
L
G
P
Q
D
L
T
Y
G
--
K
I
H
N
F
----
K
T
R
E
D
A
V
I
Y
E
A
H
V
R
D
F
T
---
S
-
D
P
A
I
A
K
D
L
T
K
--------
P
F
G
T
F
E
-----------
A
F
-------
I
-------
E
--
K
-----------
L
D
Y
L
K
D
L
G
V
T
H
I
Q
L
L
P
V
L
S
Y
Y
F
V
N
E
L
K
N
H
E
R
-------------------
L
---------------------------------------------------
S
D
Y
A
S
S
N
S
N
Y
N
W
G
Y
D
P
Q
N
Y
F
S
L
T
G
M
Y
S
S
D
P
K
---
N
P
E
K
R
I
A
E
F
K
N
L
I
N
E
I
H
K
-
R
G
M
G
A
I
L
D
V
V
Y
N
H
T
--
A
K
--
V
---
D
------
L
------
F
E
D
L
E
P
N
Y
Y
H
F
M
D
A
-
D
G
T
P
R
T
S
F
G
-
G
G
-
R
-
L
G
T
T
H
H
M
T
K
R
L
L
I
D
S
I
K
Y
L
V
D
T
Y
K
V
D
G
F
R
F
D
M
M
G
D
H
D
A
--
A
--------
S
I
E
--
E
A
Y
K
A
A
R
--
A
L
--------------------------------------
N
--------
P
N
L
I
M
L
G
E
G
W
R
T
Y
A
G
D
E
N
M
P
T
K
A
A
D
Q
D
W
M
K
H
T
D
T
V
A
V
F
S
D
D
I
R
N
N
----
L
K
S
G
Y
P
N
E
------
G
------
Q
P
A
F
I
T
G
G
K
R
---------------
D
V
--------------
N
T
-------------------
I
F
K
----
N
L
I
--------------------
A
-------------------------
Q
-------------------------
P
T
-----
N
F
--
E
A
D
S
-----
P
G
D
V
I
Q
Y
I
A
A
H
D
D
L
T
L
F
D
I
I
A
Q
S
I
K
K
D
P
S
---------------------
K
A
------------------------
E
N
Y
A
E
I
H
R
R
L
R
L
G
N
L
M
V
L
T
A
Q
G
T
P
F
I
H
S
G
Q
E
Y
G
R
T
K
Q
F
R
N
P
A
Y
R
T
P
V
A
E
D
K
V
P
N
K
S
H
L
L
R
D
K
D
G
N
P
F
D
Y
P
Y
F
I
H
D
S
Y
D
S
S
D
A
V
N
K
F
D
W
T
K
A
T
D
G
------------
K
------------
A
Y
---------------
P
----------------
E
N
V
K
S
R
D
Y
M
K
G
L
I
A
L
R
Q
S
T
D
A
F
R
L
K
S
L
Q
D
I
K
-
D
R
V
H
L
I
T
V
P
G
Q
-
N
----
G
V
E
K
E
D
V
V
I
G
Y
Q
I
T
A
P
------------
N
----
G
----
D
I
Y
A
V
F
V
N
A
D
E
K
A
R
E
F
N
L
G
T
A
F
A
H
L
R
N
A
E
---
V
L
A
D
E
N
Q
A
G
P
V
-
G
I
A
----
N
P
-----------
K
G
L
E
W
T
E
K
G
L
K
L
N
A
L
T
A
T
V
L
R
V
S
Q
N
--------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
78.82
57%
-50
- C2 -
-
3FAW
-
?
A:
[37-814]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
V
Q
L
K
D
A
Q
Q
T
D
L
T
S
I
Q
A
--
S
F
T
T
L
D
---
K
T
E
I
----
L
K
E
L
K
V
T
D
K
N
--
Q
-
N
A
--
I
Q
I
S
D
-------------------
I
T
L
--
D
T
-------------------------
S
K
S
L
L
I
I
K
G
D
F
N
---
P
K
-
Q
G
H
F
N
I
S
Y
N
-
G
N
-----
N
-----
V
T
T
R
Q
S
W
E
F
K
-----
D
Q
L
Y
---
A
Y
---
S
G
-
N
L
G
A
V
L
N
Q
D
G
S
K
V
E
A
S
L
W
S
P
S
A
D
S
V
T
M
I
I
Y
D
K
D
N
Q
N
R
--
V
V
A
T
T
P
L
V
-
K
---
N
-
N
K
G
V
W
Q
T
I
L
D
T
--
K
L
G
I
K
N
Y
T
G
Y
Y
Y
L
Y
E
I
K
R
G
-------------
K
---------
D
------
K
V
K
I
L
D
P
Y
A
K
S
L
A
E
W
D
S
N
-------
T
V
-
N
-
D
-----
D
---
I
K
T
A
-------
K
A
A
F
-
V
N
P
S
--
Q
L
G
P
Q
N
L
S
F
A
--
K
I
A
N
F
----
K
G
R
Q
D
A
V
I
Y
E
A
H
V
R
D
F
T
---
S
-
D
Q
S
L
D
G
K
L
K
N
--------
Q
L
G
T
F
A
-----------
A
F
-------
S
-------
E
--
K
-----------
L
D
Y
L
Q
K
L
G
V
T
H
I
Q
L
L
P
V
L
S
Y
F
Y
V
N
E
M
-
D
K
S
R
-------------------
S
---------------------------------------------------
T
A
Y
T
S
S
D
N
N
Y
N
W
G
Y
D
P
Q
S
Y
F
A
L
S
G
M
Y
S
E
K
P
K
---
D
P
S
A
R
I
A
E
L
K
Q
L
I
H
D
I
H
K
-
R
G
M
G
V
I
L
D
V
V
Y
N
H
T
--
A
K
--
T
---
Y
------
L
------
F
E
D
I
E
P
N
Y
Y
H
F
M
N
E
-
D
G
S
P
R
E
S
F
G
-
G
G
-
R
-
L
G
T
T
H
A
M
S
R
R
V
L
V
D
S
I
K
Y
L
T
S
E
F
K
V
D
G
F
R
F
D
M
M
G
D
H
D
A
--
A
--------
A
I
E
--
L
A
Y
K
E
A
K
--
A
I
--------------------------------------
N
--------
P
N
M
I
M
I
G
E
G
W
R
T
F
Q
G
D
Q
G
K
P
V
K
P
A
D
Q
D
W
M
K
S
T
D
T
V
G
V
F
S
D
D
I
R
N
S
----
L
K
S
G
F
P
N
E
------
G
------
T
P
A
F
I
T
G
G
P
Q
---------------
S
L
--------------
Q
G
-------------------
I
F
K
----
N
I
K
--------------------
A
-------------------------
Q
-------------------------
P
G
-----
N
F
--
E
A
D
S
-----
P
G
D
V
V
Q
Y
I
A
A
H
D
N
L
T
L
H
D
V
I
A
K
S
I
N
K
D
P
K
---------------------
V
A
------------------------
E
E
--
D
I
H
R
R
L
R
L
G
N
V
M
I
L
T
S
Q
G
T
A
F
I
H
S
G
Q
E
Y
G
R
T
K
R
L
L
N
P
D
Y
M
T
K
V
S
D
D
K
L
P
N
K
A
T
L
I
E
A
V
K
----
E
Y
P
Y
F
I
H
D
S
Y
D
S
S
D
A
I
N
H
F
D
W
A
A
A
T
D
N
------------
N
------------
K
H
---------------
P
----------------
I
S
T
K
T
Q
A
Y
T
A
G
L
I
T
L
R
R
S
T
D
A
F
R
K
L
S
K
A
E
I
D
-
R
E
V
S
L
I
T
E
V
G
Q
-
G
----
D
I
K
E
K
D
L
V
I
A
Y
Q
T
I
D
S
------------
K
----
G
----
D
I
Y
A
V
F
V
N
A
D
S
K
A
R
N
V
L
L
G
E
K
Y
K
H
L
L
K
G
Q
---
V
I
V
D
A
D
Q
A
G
I
K
-
P
I
S
----
T
P
-----------
R
G
V
H
F
E
K
D
S
L
L
I
D
P
L
T
A
I
V
I
K
V
G
----------------------------------------------------------------------------------------------------------------------------------
73
HHSearch
78.76
58%
-50
- C2 -
-
3FAW
-
?
A:
[37-814]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
V
Q
L
K
D
A
Q
Q
T
D
L
T
S
I
Q
A
--
S
F
T
T
L
D
---
K
T
E
I
----
L
K
E
L
K
V
T
D
K
N
--
Q
-
N
A
--
I
Q
I
S
D
-------------------
I
T
L
--
D
T
-------------------------
S
K
S
L
L
I
I
K
G
D
F
N
---
P
K
-
Q
G
H
F
N
I
S
Y
N
-
G
N
-----
N
-----
V
T
T
R
Q
S
W
E
F
K
-----
D
Q
L
Y
---
A
Y
---
S
G
-
N
L
G
A
V
L
N
Q
D
G
S
K
V
E
A
S
L
W
S
P
S
A
D
S
V
T
M
I
I
Y
D
K
D
N
Q
N
R
--
V
V
A
T
T
P
L
V
-
K
---
N
-
N
K
G
V
W
Q
T
I
L
D
T
--
K
L
G
I
K
N
Y
T
G
Y
Y
Y
L
Y
E
I
K
R
G
-------------
K
---------
D
------
K
V
K
I
L
D
P
Y
A
K
S
L
A
E
W
D
S
N
T
V
--------
N
-
D
-----
D
---
I
K
T
A
-------
K
A
A
F
-
V
N
P
S
--
Q
L
G
P
Q
N
L
S
F
A
--
K
I
A
N
F
----
K
G
R
Q
D
A
V
I
Y
E
A
H
V
R
D
F
T
---
S
-
D
Q
S
L
D
G
K
L
K
N
--------
Q
L
G
T
F
A
-----------
A
F
-------
S
-------
E
--
K
-----------
L
D
Y
L
Q
K
L
G
V
T
H
I
Q
L
L
P
V
L
S
Y
F
Y
V
N
E
M
D
K
S
-
R
-------------------
S
---------------------------------------------------
T
A
Y
T
S
S
D
N
N
Y
N
W
G
Y
D
P
Q
S
Y
F
A
L
S
G
M
Y
S
E
K
P
K
---
D
P
S
A
R
I
A
E
L
K
Q
L
I
H
D
I
H
K
-
R
G
M
G
V
I
L
D
V
V
Y
N
H
T
--
A
K
--
T
---
Y
------
L
------
F
E
D
I
E
P
N
Y
Y
H
F
M
N
E
-
D
G
S
P
R
E
S
F
G
-
G
G
-
R
-
L
G
T
T
H
A
M
S
R
R
V
L
V
D
S
I
K
Y
L
T
S
E
F
K
V
D
G
F
R
F
D
M
M
G
D
H
D
A
--
A
--------
A
I
E
--
L
A
Y
K
E
A
K
--
A
I
--------------------------------------
N
--------
P
N
M
I
M
I
G
E
G
W
R
T
F
Q
G
D
Q
G
K
P
V
K
P
A
D
Q
D
W
M
K
S
T
D
T
V
G
V
F
S
D
D
I
R
N
S
----
L
K
S
G
F
P
N
E
------
G
------
T
P
A
F
I
T
G
G
P
Q
---------------
S
L
--------------
Q
G
-------------------
I
F
K
----
N
I
K
--------------------
A
-------------------------
Q
-------------------------
P
G
-----
N
F
--
E
A
D
S
-----
P
G
D
V
V
Q
Y
I
A
A
H
D
N
L
T
L
H
D
V
I
A
K
S
I
N
K
D
P
K
-----------------------------------------------
V
A
E
E
D
I
H
R
R
L
R
L
G
N
V
M
I
L
T
S
Q
G
T
A
F
I
H
S
G
Q
E
Y
G
R
T
K
R
L
L
N
P
D
Y
M
T
K
V
S
D
D
K
L
P
N
K
A
T
L
I
E
A
----
V
K
E
Y
P
Y
F
I
H
D
S
Y
D
S
S
D
A
I
N
H
F
D
W
A
A
A
T
D
N
------------
N
------------
K
H
---------------
P
----------------
I
S
T
K
T
Q
A
Y
T
A
G
L
I
T
L
R
R
S
T
D
A
F
R
K
L
S
K
A
E
I
D
-
R
E
V
S
L
I
T
E
V
G
Q
-
G
----
D
I
K
E
K
D
L
V
I
A
Y
Q
T
I
D
S
------------
K
----
G
----
D
I
Y
A
V
F
V
N
A
D
S
K
A
R
N
V
L
L
G
E
K
Y
K
H
L
L
K
G
Q
---
V
I
V
D
A
D
Q
A
G
I
K
-
P
I
S
----
T
P
-----------
R
G
V
H
F
E
K
D
S
L
L
I
D
P
L
T
A
I
V
I
K
V
G
----------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
78.56
57%
-49
- C2 -
-
3FAX
1
?
A:
[38-815]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
Q
L
K
D
A
Q
Q
T
D
L
T
S
I
Q
A
--
S
F
T
T
L
D
G
V
D
K
T
E
I
----
L
K
E
L
K
V
T
D
K
---
Q
-
N
A
--
I
Q
I
S
D
-------------------
I
T
L
--
D
T
-------------------------
S
K
S
L
L
I
I
K
G
D
F
N
---
P
K
-
Q
G
H
F
N
I
S
Y
N
--
N
-----
N
-----
V
T
T
R
Q
S
W
E
F
K
-----
D
Q
L
Y
---
A
Y
---
S
G
-
N
L
G
A
V
L
N
Q
D
G
S
K
V
E
A
S
L
W
S
P
S
A
D
S
V
T
M
I
I
Y
D
K
D
N
Q
N
R
--
V
V
A
T
T
P
L
V
-
K
---
N
-
N
K
G
V
W
Q
T
I
L
D
T
--
K
L
G
I
K
N
Y
T
G
Y
Y
Y
L
Y
E
I
K
R
G
-----------------------
D
------
K
V
K
I
L
D
P
Y
A
K
S
L
A
E
W
D
S
N
-------
T
V
-
N
-
D
-----
D
---
I
K
T
A
-------
K
A
A
F
-
V
N
P
S
--
Q
L
G
P
Q
N
L
S
F
A
--
K
I
A
N
F
----
K
G
R
Q
D
A
V
I
Y
E
A
H
V
R
D
F
T
---
S
-
D
Q
S
L
D
G
--
K
N
--------
Q
L
G
T
F
A
-----------
A
F
-------
S
-------
E
--
K
-----------
L
D
Y
L
Q
K
L
G
V
T
H
I
Q
L
L
P
V
L
S
Y
F
Y
V
N
E
M
-
D
K
S
R
-------------------
S
---------------------------------------------------
T
A
Y
T
S
S
D
N
N
Y
N
W
G
Y
D
P
Q
S
Y
F
A
L
S
G
M
Y
S
E
K
P
K
---
D
P
S
A
R
I
A
E
L
K
Q
L
I
H
D
I
H
K
-
R
G
M
G
V
I
L
D
V
V
Y
N
H
T
--
A
K
--
T
---
Y
------
L
------
F
E
D
I
E
P
N
Y
Y
H
F
M
N
E
-
D
G
S
P
R
E
S
F
G
-
G
G
-
R
-
L
G
T
T
H
A
M
S
R
R
V
L
V
D
S
I
K
Y
L
T
S
E
F
K
V
D
G
F
R
F
D
M
M
G
D
H
D
A
--
A
--------
A
I
E
--
L
A
Y
K
E
A
K
--
A
I
--------------------------------------
N
--------
P
N
M
I
M
I
G
E
G
W
R
T
F
Q
G
D
Q
G
K
P
V
K
P
A
D
Q
D
W
M
K
S
T
D
T
V
G
V
F
S
D
D
I
R
N
S
----
L
K
S
G
F
P
N
E
------
G
------
T
P
A
F
I
T
G
G
P
Q
---------------
S
L
--------------
Q
G
-------------------
I
F
K
----
N
I
K
--------------------
A
-------------------------
Q
-------------------------
P
G
-----
N
F
--
E
A
D
S
-----
P
G
D
V
V
Q
Y
I
A
A
H
D
N
L
T
L
H
D
V
I
A
K
S
I
N
K
D
P
K
---------------------
V
A
------------------------
E
E
--
D
I
H
R
R
L
R
L
G
N
V
M
I
L
T
S
Q
G
T
A
F
I
H
S
G
Q
E
Y
G
R
T
K
R
L
L
N
P
D
Y
M
T
K
V
S
-
D
K
L
P
N
K
A
T
L
I
E
A
V
K
----
E
Y
P
Y
F
I
H
D
S
Y
D
S
S
D
A
I
N
H
F
D
W
A
A
A
T
D
N
------------
N
------------
K
H
---------------
P
----------------
I
S
T
K
T
Q
A
Y
T
A
G
L
I
T
L
R
R
S
T
D
A
F
R
K
L
S
K
A
E
I
D
-
R
E
V
S
L
I
T
E
V
G
Q
-
G
----
D
I
K
E
K
D
L
V
I
A
Y
Q
T
I
D
S
-----------------
G
----
D
I
Y
A
V
F
V
N
A
D
S
K
A
R
N
V
L
L
G
E
K
Y
K
H
L
L
K
G
Q
---
V
I
V
D
A
D
Q
A
G
I
K
-
P
I
S
----
T
P
-----------
R
G
V
H
F
E
K
D
S
L
L
I
D
P
L
T
A
I
V
I
K
V
G
K
---------------------------------------------------------------------------------------------------------------------------------
64
Fugue
78.32
58%
-49
- C2 -
-
3FAW
-
?
A:
[37-814]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
V
Q
L
K
D
A
Q
Q
T
D
L
T
S
I
Q
A
--
S
F
T
T
L
D
K
T
E
I
L
K
E
----
L
---
K
V
T
D
K
N
--
Q
-
N
A
--
I
Q
I
S
D
-------------------
I
T
L
--
D
T
-------------------------
S
K
S
L
L
I
I
K
G
D
F
N
---
P
K
-
Q
G
H
F
N
I
S
Y
N
-
G
N
-----
N
-----
V
T
T
R
Q
S
W
E
F
K
-----
D
Q
L
Y
---
A
Y
---
S
G
-
N
L
G
A
V
L
N
Q
D
G
S
K
V
E
A
S
L
W
S
P
S
A
D
S
V
T
M
I
I
Y
D
K
D
N
Q
N
R
--
V
V
A
T
T
P
L
V
-
K
---
N
-
N
K
G
V
W
Q
T
I
L
D
--
T
K
L
G
I
K
N
Y
T
G
Y
Y
Y
L
Y
E
I
K
R
G
-------------
K
---------
D
------
K
V
K
I
L
D
P
Y
A
K
S
L
A
E
W
D
S
N
T
V
--------
N
-
D
-----
D
---
I
K
T
A
-------
K
A
A
F
-
V
N
P
S
--
Q
L
G
P
Q
N
L
S
F
A
--
K
I
A
N
F
----
K
G
R
Q
D
A
V
I
Y
E
A
H
V
R
D
F
T
---
S
-
D
Q
S
L
D
G
K
L
K
N
--------
Q
L
G
T
F
A
-----------
A
F
-------
S
-------
E
--
K
-----------
L
D
Y
L
Q
K
L
G
V
T
H
I
Q
L
L
P
V
L
S
Y
F
Y
V
N
E
-
M
D
K
S
R
-------------------
S
---------------------------------------------------
T
A
Y
T
S
S
D
N
N
Y
N
W
G
Y
D
P
Q
S
Y
F
A
L
S
G
M
Y
S
E
K
P
K
---
D
P
S
A
R
I
A
E
L
K
Q
L
I
H
D
I
H
K
-
R
G
M
G
V
I
L
D
V
V
Y
N
H
T
--
A
K
--
T
---
Y
------
L
------
F
E
D
I
E
P
N
Y
Y
H
F
M
N
E
-
D
G
S
P
R
E
S
F
G
-
G
G
-
R
-
L
G
T
T
H
A
M
S
R
R
V
L
V
D
S
I
K
Y
L
T
S
E
F
K
V
D
G
F
R
F
D
M
M
G
D
H
D
A
--
A
--------
A
I
E
--
L
A
Y
K
E
A
K
--
A
I
--------------------------------------
N
--------
P
N
M
I
M
I
G
E
G
W
R
T
F
Q
G
D
Q
G
K
P
V
K
P
A
D
Q
D
W
M
K
S
T
D
T
V
G
V
F
S
D
D
I
R
N
S
----
L
K
S
G
F
P
N
E
------
G
------
T
P
A
F
I
T
G
G
P
Q
---------------
S
L
--------------
Q
G
-------------------
I
F
K
----
N
I
K
--------------------
A
-------------------------
Q
-------------------------
P
G
-----
N
F
--
E
A
D
S
-----
P
G
D
V
V
Q
Y
I
A
A
H
D
N
L
T
L
H
D
V
I
A
K
S
I
N
K
D
P
K
---------------------
V
A
------------------------
E
--
E
D
I
H
R
R
L
R
L
G
N
V
M
I
L
T
S
Q
G
T
A
F
I
H
S
G
Q
E
Y
G
R
T
K
R
L
L
N
P
D
Y
M
T
K
V
S
D
D
K
L
P
N
K
A
T
L
I
----
E
A
V
K
E
Y
P
Y
F
I
H
D
S
Y
D
S
S
D
A
I
N
H
F
D
W
A
A
A
T
D
N
------------
N
------------
K
H
---------------
P
----------------
I
S
T
K
T
Q
A
Y
T
A
G
L
I
T
L
R
R
S
T
D
A
F
R
K
L
S
K
A
E
I
D
-
R
E
V
S
L
I
T
E
V
G
Q
-
G
----
D
I
K
E
K
D
L
V
I
A
Y
Q
T
I
D
S
------------
K
----
G
----
D
I
Y
A
V
F
V
N
A
D
S
K
A
R
N
V
L
L
G
E
K
Y
K
H
L
L
K
G
Q
---
V
I
V
D
A
D
Q
A
G
I
K
-
P
I
S
----
T
P
-----------
R
G
V
H
F
E
K
D
S
L
L
I
D
P
L
T
A
I
V
I
K
V
G
----------------------------------------------------------------------------------------------------------------------------------
82
HHSearch
53.16
30%
26
* C2 *
-
4AIO
4
?
A:
[110-883]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
T
G
L
Q
L
P
G
V
L
-----
D
D
M
F
---
A
Y
---
T
G
-
P
L
G
A
V
F
S
E
D
--
S
V
S
L
H
L
W
A
P
T
A
Q
G
V
S
V
C
F
F
D
G
P
A
G
P
-----
A
L
E
T
V
Q
L
K
---
E
-
S
N
G
V
W
S
V
T
G
P
R
-------
E
W
E
N
R
Y
Y
L
Y
E
V
D
V
Y
-------------
H
---------
P
TKAQV
L
K
C
L
A
G
D
P
Y
A
R
S
L
S
A
N
G
A
R
----------------------------------
T
W
L
-
V
D
I
N
NE
T
L
K
P
A
S
W
D
E
L
AD
E
K
P
K
L
----
D
S
F
S
D
I
T
I
Y
E
L
H
I
R
D
F
S
---
A
-
H
D
G
T
V
D
--
S
D
--------
S
R
G
G
F
R
-----------
A
F
A
YQAS
A
G
M
-------
E
--
H
-----------
L
R
K
L
S
D
A
G
L
T
H
V
H
L
L
P
S
F
H
F
A
G
V
D
D
I
K
S
N
W
K
F
V
D
E
C
E
L
A
T
FPPGSD
M
Q
Q
A
A
---------------------------------------------------
V
V
A
I
Q
E
E
D
P
Y
N
W
G
Y
N
P
V
L
W
G
V
P
K
G
S
Y
A
S
D
P
D
---
G
P
-
S
R
I
I
E
Y
R
Q
M
V
Q
A
L
N
R
-
I
G
L
R
V
V
M
D
V
V
Y
N
H
L
--
D
S
--
S
---
G
PCGISS
V
------
L
D
K
I
V
P
G
Y
Y
V
R
R
D
T
-
N
G
Q
I
E
N
S
A
A
-
M
N
-
N
-
T
A
S
E
H
F
M
V
D
R
L
I
V
D
D
L
L
N
W
A
V
N
Y
K
V
D
G
F
R
F
D
L
M
G
H
I
M
K
--
R
--------
T
M
M
--
R
A
K
S
A
L
Q
--
S
L
--------------------------------------
T
TDAHGVDG
S
K
I
Y
L
Y
G
E
G
W
D
F
A
E
V
A
R
N
Q
R
G
I
N
G
S
Q
L
N
M
S
G
-
T
G
I
G
S
F
N
D
R
I
R
D
A
----
I
N
G
G
N
P
F
G
NP----
L
------
Q
Q
G
F
N
T
G
L
F
L
EPNGFYQGN
E
A
D
T
R
R
S
L
--------------
A
T
-------------------
Y
A
D
Q
I
Q
I
G
L
A
--------------------
G
NLRDYVLISHTG
E
A
K
K
GSEIHTFDG
L
-------------------------
P
V
-----
G
Y
---
T
A
S
-----
P
I
E
T
I
N
Y
V
S
A
H
D
N
E
T
L
F
D
V
I
S
V
K
T
P
M
I
L
-------------------------------------------------
S
V
D
E
R
C
R
I
N
H
L
A
S
S
M
M
A
L
S
Q
G
I
P
F
F
H
A
G
D
E
I
L
R
S
K
S
I
D
----------------------------------
R
D
S
Y
N
S
G
D
W
F
N
K
L
D
F
T
Y
E
T
N
N
WGVGLPPSEKNE
D
------------
N
W
---------------
P
LM
K
P
R
L
E
NPSFKPA
K
G
H
I
L
A
A
L
D
S
F
V
D
I
L
K
I
R
Y
S
S
P
L
F
R
L
S
T
A
N
D
I
K
-
Q
R
V
R
F
H
N
T
G
---------
P
S
L
V
P
G
V
I
V
M
G
I
E
D
A
RGESPEMAQLDT
N
----
F
----
S
Y
V
V
T
V
F
N
V
C
P
H
E
V
S
M
D
I
P
A
L
A
--
S
M
G
F
E
LH
P
V
Q
V
N
S
S
----
D
-
T
L
V
----
R
K
-----------
S
A
Y
E
A
A
T
G
R
F
T
V
P
G
R
T
V
S
V
F
V
E
P
R
---------------------------------------------------------------------------------------------------------------------------------
75
HHSearch
52.58
25%
46
- C2 -
-
2YOC
-
PULA_KLEPN
B:
[35-1064]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
T
A
V
E
N
Q
A
V
I
H
L
V
-------
D
I
AGITSSS
A
A
D
Y
S
S
K
N
L
Y
L
W
N
N
E
T
CDALS
A
P
-
V
A
D
W
N
D
V
S
T
T
P
S
G
S
D
K
Y
G
P
Y
W
V
I
P
L
N
K
E
S
G
C
I
N
V
I
V
R
D
G
T
D
-
K
----
L
I
D
S
D
L
R
V
A
F
G
-
D
F
T
D
R
T
V
S
V
I
A
G
N
S
A
V
Y
D
S
R
A
D
----
A
FRAA
F
G
V
A
L
A
E
A
H
W
V
D
K
N
T
L
L
W
--
P
G
G
Q
D
K
P
--
I
V
R
L
YYSH
S
S
K
V
A
A
D
G
E
G
KF
T
D
R
Y
--
L
K
L
T
P
TTVSQQVSMRFPHLSSYAA
F
K
L
P-
D
N
-------------------------
A
N
V
D
E
L
L
Q
G
E
T
V
----------
A
I
A
A
A
E
D
G
ILI--
S
-----
A
T
Q
V
Q
T
A
G
V
L
-----
D
D
A
Y
AEA
A
E
---
A
L
-
S
Y
G
A
Q
L
A
D
-
G
-
G
V
T
F
R
V
W
A
P
T
A
Q
Q
V
D
V
V
V
Y
S
A
D
K
K
----
V
I
G
S
H
P
M
T
-
R
---
D
S
A
S
G
A
W
S
W
Q
G
G
S
-------
D
L
K
G
A
F
Y
R
Y
A
M
T
V
Y
HPQSRK-------
V
---------
E
------
Q
Y
E
V
T
D
P
Y
A
H
S
L
S
T
N
S
E
Y
----------------------------------
S
Q
V
-
V
D
L
N
DS
A
L
K
P
D
G
W
D
N
L
--
T
M
P
H
A
QKTK
A
D
L
A
K
M
T
I
H
E
S
H
I
R
D
L
S
---
A
W
D
Q
T
V
P
---
A
E
--------
L
R
G
K
Y
L
-----------
A
L
-------
T
AGDSNMV
Q
--
H
-----------
L
K
T
L
S
A
S
G
V
T
H
V
E
L
L
P
V
F
D
L
A
T
V
N
E
F
S
D
K
V
A
-------------------
D
IQQPFSRLCEVNSAVKSSEFAGYCDSGSTVEEVLNQLKQSDSQDNPQVQAL
N
T
L
V
A
Q
T
D
S
Y
N
W
G
Y
D
P
F
H
Y
T
V
P
E
G
S
Y
A
T
D
P
----
E
G
T
T
R
I
K
E
F
R
T
M
I
Q
A
I
K
Q
D
L
G
M
N
V
I
M
D
V
V
Y
N
H
T
--
N
A
--
A
---
G
------
P
TDRTSV
L
D
K
I
V
P
W
Y
Y
Q
R
L
N
E
T
T
G
S
V
E
S
A
T
C
-
C
S
-
D
-
S
A
P
E
H
R
M
F
A
K
L
I
A
D
S
L
A
V
W
T
T
D
Y
K
I
D
G
F
R
F
D
L
M
G
Y
H
P
K
--
A
--------
Q
I
L
--
S
A
W
E
R
I
K
--
A
L
--------------------------------------
N
--------
P
D
I
Y
F
F
G
E
G
W
D
S
N
Q
S
D
R
---
F
E
I
A
S
Q
I
N
L
K
G
-
T
G
I
G
T
F
S
D
R
L
R
D
S
----
V
R
G
G
G
P
F
D
SGDALR
Q
------
N
Q
G
I
G
S
G
A
G
V
---------------
L
P
--------------
N
E
LASLSDDQVRHLADLTRLG
M
A
G
----
N
L
A
DFVMIDKDGAAKK-------
G
-------------------------
S
EIDYNGA------------------
P
G
-----
G
Y
---
A
A
D
-----
P
T
E
V
V
N
Y
V
S
K
H
D
N
Q
T
L
W
D
M
I
S
Y
K
A
S
Q
E
A
-------------------------------------------------
D
L
A
T
R
V
R
M
Q
A
V
S
L
A
T
V
M
L
G
Q
G
I
A
F
D
Q
Q
G
S
E
L
L
R
S
K
S
F
T
----------------------------------
R
D
S
Y
D
S
G
D
W
F
N
R
V
D
Y
S
L
Q
D
N
N
YNVGMPRISDDG
S
------------
N
Y
---------------
E
VITRVKEMVATPGEA-
E
L
K
Q
M
T
A
F
Y
Q
E
L
T
E
L
R
K
S
S
P
L
F
T
L
G
D
G
S
A
V
M
-
K
R
V
D
F
R
N
T
G
---------
S
D
Q
Q
A
G
L
L
V
M
T
V
D
D
G
MKAGASLDS---
R
----
L
----
D
G
L
V
V
A
I
N
A
A
P
E
S
R
T
L
N
E
F
A
G
E
--
T
L
Q
L
S
---
A
I
Q
Q
T
A
G
--
E
N
-
S
L
A
----
N
G
-----------
V
Q
I
-
A
A
D
G
T
V
T
L
P
A
W
S
V
A
V
L
E
L
P
Q
G
E
A
Q
G
A
---------------------------------------------------------------------------------------------------------------------------
80
HHSearch
52.56
29%
31
- C2 -
-
3WDH
-
?
A:
[10-709]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
F
E
A
Y
L
D
E
L
T
M
I
T
I
--
L
F
P
C
H
V
D
Q
K
R
A
-------
P
I
F
F
L
R
D
D
K
--
K
-
T
A
Y
R
L
T
I
R
S
-------------------
S
E
K
--
H
H
-------------------------
S
F
I
K
Y
E
C
L
V
P
F
I
---
V
E
L
G
K
R
Y
V
V
Y
T
E
-
E
G
W
Q
V
P
L
Q
-----
V
G
A
V
M
R
T
K
A
F
-----
D
D
L
Y
---
A
Y
---
D
G
N
D
L
G
A
T
Y
D
P
-
E
-
K
T
T
F
K
V
W
A
P
T
A
T
D
V
L
L
K
L
I
H
P
T
T
K
----
E
E
T
T
Y
V
M
T
-
R
---
E
-
K
K
G
L
W
T
Y
T
V
Y
D
-------
D
V
E
R
F
L
Y
T
Y
M
T
Y
V
N
-------------
F
---------
I
------
W
R
E
A
V
D
P
Y
A
K
S
V
S
V
N
G
T
----------------------------------
Y
G
V
V
-
V
D
L
A
--
K
T
N
I
P
K
---
P
--
S
M
S
L
F
----
I
S
M
T
D
A
I
I
Y
E
M
H
I
R
D
F
T
---
I
-
H
H
E
S
G
V
---
R
--------
Q
K
G
K
Y
V
G
L
T
ERGTTGPN
G
T
-------
L
-------
T
--
G
-----------
L
S
Y
I
K
Q
L
G
V
T
H
V
Q
L
M
P
V
Q
D
F
E
G
V
D
E
L
Q
P
--------------------------------------------------------------------------------
L
K
M
Y
N
W
G
Y
N
T
V
H
Y
N
A
P
E
G
S
Y
A
T
D
P
D
---
D
P
Y
A
R
I
I
E
L
K
R
A
I
R
A
F
Q
Q
-
E
G
I
R
V
I
L
D
V
V
Y
N
H
V
--
Y
V
--
R
ET-
S
------
S
------
F
E
H
L
V
P
G
Y
Y
F
R
Y
E
R
-
N
G
Y
P
S
N
G
T
G
-
V
G
N
D
-
L
A
S
E
R
K
M
V
K
K
F
I
I
D
S
V
T
Y
W
L
K
E
Y
G
V
D
G
F
R
F
D
L
M
G
I
L
D
I
--
D
--------
T
M
N
--
D
V
R
R
A
I
D
--
E
I
--------------------------------------
D
--------
P
T
V
I
I
L
G
E
G
W
D
L
A
T
P
L
P
S
--
E
K
K
T
T
I
A
N
A
K
H
T
P
R
I
A
Y
F
N
D
R
F
R
D
Y
----
V
K
G
S
T
F
D
I
------
H
------
E
R
G
F
A
L
G
D
C
S
---------------
Y
K
--------------
E
A
-------------------
V
I
G
----
A
I
R
--------------------
G
-------------------------
S
-------------------------
I
H
-----
L
----
F
F
S
-----
P
R
Q
S
V
N
Y
V
E
C
H
D
N
H
T
L
W
D
K
M
A
V
A
N
A
H
E
--------------------------------------------------
S
E
Y
I
R
R
K
R
Q
K
L
A
T
A
I
V
L
L
S
Q
G
I
P
F
L
H
S
G
Q
E
F
Y
R
T
K
K
G
V
----------------------------------
E
N
S
Y
N
S
P
D
E
V
N
Q
V
D
W
N
E
K
S
R
W
-------------------------------------------------------------
E
E
D
V
R
E
I
M
K
L
I
E
L
R
K
K
H
G
A
F
R
F
L
T
A
D
Q
V
R
-
R
H
M
K
F
Y
D
-------------
T
H
P
S
V
I
A
Y
Q
L
V
D
V
------------
G
VYGP
W
----
K
Q
I
V
V
V
Y
H
N
E
E
K
K
A
M
L
P
L
A
D
-----
G
K
W
K
---
V
M
F
S
S
E
---
L
G
-
N
-----------------------
V
C
E
Q
F
I
E
I
N
G
I
G
A
W
V
L
I
Q
-----------------------------------------------------------------------------------------------------------------------------------
74
HHSearch
52.40
25%
38
- C2 -
-
2FHF
3
PULA_KLEAE
A:
[48-1075]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
A
S
A
R
Q
A
V
I
H
L
V
D
I
A
G
ITS
S
T
-------
P
A
D
Y
A
T
K
N
L
Y
L
W
N
N
E
T
CDALS
A
P
-
V
A
D
W
N
D
V
S
T
T
P
T
G
S
D
K
Y
G
P
Y
W
V
I
P
L
T
K
E
S
G
C
I
N
V
I
V
R
D
G
T
N
K
L
-----
I
D
S
D
L
R
V
S
F
S
D
F
-
T
D
R
T
V
S
V
I
A
G
N
S
A
V
Y
D
S
R
A
D
A
F
R
A
A
----
F
G
V
A
L
A
D
A
H
W
V
D
K
T
T
L
L
W
--
P
G
G
E
N
K
P
--
I
V
R
L
Y
Y
S
H
S
S
K
V
A
A
D
S
N
---
G
--
E
--
F
S
D
K
Y
-------------------
V
K
L
--
T
P
T
T
V
N
Q
Q
V
S
M
R
FPHLAS
Y
P
A
F
K
L
P
DD
V
N
V
D
E
L
L
Q
G
E
T
V
----------
A
I
A
A
E
S
D
G
ILS--
S
-----
A
T
Q
V
Q
T
A
G
V
L
-----
D
D
T
Y
---
A
A
A
A
E
A
L
-
S
Y
G
A
Q
L
T
D
-
S
-
G
V
T
F
R
V
W
A
P
T
A
Q
Q
V
E
L
V
I
Y
S
A
D
K
K
----
V
I
A
S
H
P
M
T
-
R
---
D
S
A
S
G
A
W
S
W
Q
G
G
S
-------
D
L
K
G
A
F
Y
R
Y
A
M
T
V
Y
HPQSRK-------
V
---------
E
------
Q
Y
E
V
T
D
P
Y
A
H
S
L
S
T
N
S
E
Y
----------------------------------
S
Q
V
-
V
D
L
N
DS
A
L
K
P
E
G
W
D
G
L
--
T
M
P
H
A
QKT
K
A
D
L
A
K
M
T
I
H
E
S
H
I
R
D
L
S
---
A
W
D
Q
T
V
P
A
---
E
--------
L
R
G
K
Y
L
-----------
A
L
TAQES
N
M
V
-------
Q
--
H
-----------
L
K
Q
L
S
A
S
G
V
T
H
I
E
L
L
P
V
F
D
L
A
T
V
N
E
F
S
D
K
V
A
-------------------
D
IQQP
F
S
R
L
C
E
V
N
SAVKSSEFAGYCDSGST
V
E
E
V
L
T
Q
L
KQNDSKDNP
Q
V
Q
A
L
N
T
L
V
A
Q
T
D
S
Y
N
W
G
Y
D
P
F
H
Y
T
V
P
E
G
S
Y
A
T
D
P
E
----
G
T
A
R
I
K
E
F
R
T
M
I
Q
A
I
K
Q
D
L
G
M
N
V
I
M
D
V
V
Y
N
H
T
--
N
A
--
A
---
G
------
P
TDRTSV
L
D
K
I
V
P
W
Y
Y
Q
R
L
N
E
T
T
G
S
V
E
S
A
T
C
-
C
S
-
D
-
S
A
P
E
H
R
M
F
A
K
L
I
A
D
S
L
A
V
W
T
T
D
Y
K
I
D
G
F
R
F
D
L
M
L
Y
H
P
K
--
A
--------
Q
I
L
--
S
A
W
E
R
I
K
--
A
L
--------------------------------------
N
--------
P
D
I
Y
F
F
G
E
G
W
D
S
N
Q
S
D
R
---
F
E
I
A
S
Q
I
N
L
K
G
-
T
G
I
G
T
F
S
D
R
L
R
D
A
----
V
R
G
G
G
P
F
D
------
S
GD
A
L
R
Q
N
Q
G
V
G
S
G
A
G
V
---------------
L
P
NELTTLS
D
D
Q
A
R
H
L
A
D
L
T
R
L
G
--------------
M
A
G
----
N
L
A
D
F
V
L
I
D
KDG
A
V
K
R
GSEIDYN
G
-------------------------
A
-------------------------
P
G
-----
G
Y
---
A
A
D
-----
P
T
E
V
V
N
Y
V
S
K
H
D
N
Q
T
L
W
D
M
I
S
Y
K
A
A
Q
E
A
-------------------------------------------------
D
L
D
T
R
V
R
M
Q
A
V
S
L
A
T
V
M
L
G
Q
G
I
A
F
D
Q
Q
G
S
E
L
L
R
S
K
S
F
T
----------------------------------
R
D
S
Y
D
S
G
D
W
F
N
R
V
D
Y
S
L
Q
D
N
N
------------
Y
NVGMPRSSDDGS
N
Y
D
I
I
A
R
V
KDAVATPG
E
T
----------------
E
L
K
Q
M
T
A
F
Y
Q
E
L
T
A
L
R
K
S
S
P
L
F
T
L
G
D
G
A
T
V
M
-
K
R
V
D
F
R
N
T
G
---------
A
D
Q
Q
T
G
L
L
V
M
T
I
D
D
G
MQAGASLDS---
R
----
V
----
D
G
I
V
V
A
I
N
A
A
P
E
S
R
T
L
Q
D
F
A
G
----
T
S
L
Q
----
L
S
A
I
Q
Q
A
A
G
D
R
S
L
A
----
S
G
-----------
V
Q
V
-
A
A
D
G
S
V
T
L
P
A
W
S
V
A
V
L
E
L
P
Q
G
E
S
Q
G
----------------------------------------------------------------------------------------------------------------------------
65
Fugue
51.63
27%
37
- C2 -
-
2E8Y
1
PULA_BACSU
A:
[1-712]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
V
S
I
R
R
S
F
E
A
Y
V
D
D
MN
I
I
T
V
L
I
P
A
E
Q
K
E
I
----
M
T
P
P
F
R
L
E
T
E
--
I
-
T
D
--
F
P
L
A
V
-------------------
R
E
E
--
Y
S
-------------------------
L
E
A
K
Y
K
Y
V
C
V
S
D
HPV
T
F
-
G
K
I
H
C
V
R
A
S
-
S
G
-----
H
-----
K
T
D
L
Q
I
G
A
V
I
RT
A
A
F
D
D
E
F
---
Y
Y
---
D
G
-
E
L
G
--
A
V
Y
T
A
D
H
T
V
F
K
V
W
A
P
A
A
T
S
A
A
V
K
L
S
H
P
N
K
S
G
R
--
T
F
Q
---
M
T
-
R
---
L
-
E
K
G
V
Y
A
V
T
V
T
G
-------
D
L
H
G
Y
E
Y
L
F
C
I
C
N
N
-------------
S
---------
E
------
W
M
E
T
V
D
Q
Y
A
K
A
V
T
V
---------------------------
N
G
E
-------
K
G
V
V
-
L
R
P
D
--
Q
M
K
W
T
A
P
L
------
K
P
F
----
S
H
P
V
D
A
V
I
Y
E
T
H
L
R
D
F
S
---
I
-
H
E
---
N
S
G
M
I
--------
N
K
G
K
Y
L
-----------
A
L
-------
T
-------
E
--
T
DTQTANGSSSG
L
A
Y
V
K
E
L
G
V
T
H
V
E
L
L
P
V
N
D
F
A
G
V
D
E
--------------------------------------------------------------------------------
E
K
P
L
D
A
Y
N
W
G
Y
N
P
L
H
F
F
A
P
E
G
S
Y
A
S
N
P
H
---
D
P
Q
T
R
K
T
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L
K
Q
M
I
N
T
L
H
Q
-
H
G
L
R
V
I
L
D
V
V
F
N
H
V
YK
R
E
--
N
---
S
------
P
------
F
E
K
T
V
P
G
Y
F
F
R
H
D
E
-
C
G
K
P
S
N
G
T
G
-
V
G
-
N
D
I
A
S
E
R
R
M
A
R
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A
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C
V
V
Y
W
L
E
E
Y
N
V
D
G
F
R
F
D
L
L
G
I
L
D
I
--
D
--------
T
V
L
--
Y
M
K
E
K
A
T
--
K
A
--------------------------------------
K
--------
P
G
I
L
L
F
G
E
G
W
D
L
--
A
T
P
L
P
H
E
Q
K
A
A
L
A
N
A
P
R
M
P
G
I
G
F
F
N
D
M
F
R
D
A
----
V
K
G
N
T
F
H
L
------
K
------
A
T
G
F
A
L
G
N
G
E
---------------
S
A
--------------
Q
A
-------------------
V
M
H
----
G
I
A
GSSG----------------
W
-------------------------
K
-------------------------
A
L
-----
A
P
--
I
V
P
E
-----
P
S
Q
S
I
N
Y
V
E
S
H
D
N
H
T
F
W
D
K
M
S
F
A
-----
L
---------------------
P
Q
------------------------
E
N
D
S
R
K
R
S
R
Q
R
L
A
V
A
I
I
L
L
A
Q
G
V
P
F
I
H
S
G
Q
E
F
F
R
T
K
Q
G
V
----------------------------------
E
N
S
Y
Q
S
S
D
S
I
N
Q
L
D
W
D
R
R
E
T
-------------------------------------------------------------
F
K
E
D
V
H
Y
I
R
R
L
I
S
L
R
K
A
H
P
A
F
R
L
R
S
A
A
D
I
Q
-
R
H
L
E
C
L
T
L
K
E
H
-------------
L
I
A
Y
R
L
Y
D
L
------------
D
----
E
VDEW
K
D
I
I
V
I
H
H
A
S
P
D
S
V
E
W
R
L
P
N
D
----
I
P
Y
R
---
L
L
C
D
P
S
G
F
Q
E
D
-
P
T
E
----
I
K
-----------
K
-------
T
V
A
V
N
G
I
G
T
V
I
L
Y
L
A
S
---------------------------------------------------------------------------------------------------------------------------------
81
HHSearch
51.42
30%
26
- C2 -
-
4J3V
2
?
A:
[131-904]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
T
G
L
Q
L
P
G
V
L
-----
D
D
M
F
---
A
Y
---
T
G
-
P
L
G
A
V
F
S
E
--
D
S
V
S
L
H
L
W
A
P
T
A
Q
G
V
S
V
C
F
F
D
G
P
A
G
P
-----
A
L
E
T
V
Q
L
K
---
E
-
S
N
G
V
W
S
V
T
G
P
R
-------
E
W
E
N
R
Y
Y
L
Y
E
V
D
V
Y
-------------
H
---------
P
TKAQVL
K
C
L
A
G
D
P
Y
A
R
S
L
S
A
N
G
A
R
----------------------------------
T
W
L
-
V
D
I
N
NE
T
L
K
P
A
S
W
D
E
L
AD
E
K
P
K
L
----
D
S
F
S
D
I
T
I
Y
E
L
H
I
R
D
F
S
---
A
-
H
D
G
T
V
D
--
S
D
--------
S
R
G
G
F
R
-----------
A
F
A
YQAS
A
G
M
-------
E
--
H
-----------
L
R
K
L
S
D
A
G
L
T
H
V
H
L
L
P
S
F
H
F
A
G
V
D
D
I
K
S
N
W
K
F
V
D
E
C
E
L
A
T
FPPGSD
M
Q
Q
A
A
---------------------------------------------------
V
V
A
I
Q
E
E
D
P
Y
N
W
G
Y
N
P
V
L
W
G
V
P
K
G
S
Y
A
S
D
P
D
---
G
P
-
S
R
I
I
E
Y
R
Q
M
V
Q
A
L
N
R
-
I
G
L
R
V
V
M
D
V
V
Y
N
H
L
--
D
S
--
S
---
G
PCGISS
V
------
L
D
K
I
V
P
G
Y
Y
V
R
R
D
T
-
N
G
Q
I
E
N
S
A
A
-
M
N
-
N
-
T
A
S
E
H
F
M
V
D
R
L
I
V
D
D
L
L
N
W
A
V
N
Y
K
V
D
G
F
R
F
D
L
M
G
H
I
M
K
--
R
--------
T
M
M
--
R
A
K
S
A
L
Q
--
S
L
--------------------------------------
T
TDAHGVDG
S
K
I
Y
L
Y
G
E
G
W
D
F
A
E
V
A
R
N
Q
R
G
I
N
G
S
Q
L
N
M
S
G
-
T
G
I
G
S
F
N
D
R
I
R
D
A
----
I
N
G
G
N
P
F
G
NP----
L
------
Q
Q
G
F
N
T
G
L
F
L
EPNGFYQGN
E
A
D
T
R
R
S
L
--------------
A
T
-------------------
Y
A
D
Q
I
Q
I
G
L
A
--------------------
G
-------------------------
N
LRDYVLISHTG
E
A
K
K
GSEIHTFDGL
P
V
-----
G
Y
---
T
A
S
-----
P
I
E
T
I
N
Y
V
S
A
H
D
N
E
T
L
F
D
V
I
S
V
K
T
P
M
I
L
-------------------------------------------------
S
V
D
E
R
C
R
I
N
H
L
A
S
S
M
M
A
L
S
Q
G
I
P
F
F
H
A
G
D
E
I
L
R
S
K
S
I
D
----------------------------------
R
D
S
Y
N
S
G
D
W
F
N
K
L
D
F
T
Y
E
T
N
N
WGVGLPPSEKNE
D
------------
N
W
---------------
P
L
M
K
P
R
L
E
NPSFKPA
K
G
H
I
L
A
A
L
D
S
F
V
D
I
L
K
I
R
Y
S
S
P
L
F
R
L
S
T
A
N
D
I
K
-
Q
R
V
R
F
H
N
T
G
---------
P
S
L
V
P
G
V
I
V
M
G
I
E
D
A
RGESPEMAQLDT
N
----
F
----
S
Y
V
V
T
V
F
N
V
C
P
H
E
V
S
M
D
I
P
A
L
A
--
S
M
G
F
E
LH
P
V
Q
V
N
S
S
----
D
-
T
L
V
----
R
K
-----------
S
A
Y
E
A
A
T
G
R
F
T
V
P
G
R
T
V
S
V
F
V
E
P
R
---------------------------------------------------------------------------------------------------------------------------------
77
HHSearch
50.31
27%
43
- C2 -
-
2E8Y
1
PULA_BACSU
A:
[5-712]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
R
S
F
E
A
Y
V
D
D
M
N
I
I
T
V
--
L
I
P
A
E
Q
K
E
I
M
T
-------
P
P
F
R
L
E
T
E
I
--
T
-
D
---
F
P
L
A
V
-------------------
R
E
E
Y
S
L
E
-------------------------
A
K
Y
K
Y
V
C
V
S
D
H
P
---
V
T
F
G
K
I
H
C
V
R
A
S
-
S
G
-----
H
K
T
D
LQ
I
G
A
V
I
R
T
A
A
F
-----
D
D
E
F
---
Y
Y
---
D
G
-
E
L
G
A
V
Y
T
A
D
--
H
T
V
F
K
V
W
A
P
A
A
T
S
A
A
V
K
L
S
H
P
N
K
S
-----
G
R
T
F
Q
M
T
-
R
---
L
-
E
K
G
V
Y
A
V
T
V
T
G
-------
D
L
H
G
Y
E
Y
L
F
C
I
C
N
N
-------------
S
---------
E
------
W
M
E
T
V
D
Q
Y
A
K
A
V
T
V
N
G
E
----------------------------------
K
G
V
V
-
L
R
P
D
--
Q
M
K
---
W
T
A
P
--
L
K
-
P
F
----
S
H
P
V
D
A
V
I
Y
E
T
H
L
R
D
F
S
---
I
-
H
E
N
S
G
M
I
N
K
G
KYLALTET
D
T
Q
T
A
N
-----------
G
S
-------
S
-------
S
--
G
-----------
L
A
Y
V
K
E
L
G
V
T
H
V
E
L
L
P
V
N
D
F
A
G
V
D
E
E
K
P
--------------------------------------------------------------------------------
L
D
A
Y
N
W
G
Y
N
P
L
H
F
F
A
P
E
G
S
Y
A
S
N
P
H
---
D
P
Q
T
R
K
T
E
L
K
Q
M
I
N
T
L
H
Q
-
H
G
L
R
V
I
L
D
V
V
F
N
H
V
--
Y
K
RE
N
---
S
------
P
------
F
E
K
T
V
P
G
Y
F
F
R
H
D
E
-
C
G
K
P
S
N
G
T
G
-
V
G
N
D
-
I
A
S
E
R
R
M
A
R
K
F
I
A
D
C
V
V
Y
W
L
E
E
Y
N
V
D
G
F
R
F
D
L
L
G
I
L
D
I
--
D
--------
T
V
L
--
Y
M
K
E
K
A
T
--
K
A
--------------------------------------
K
--------
P
G
I
L
L
F
G
E
G
W
D
L
A
T
P
L
P
H
--
E
Q
K
A
A
L
A
N
A
P
R
M
P
G
I
G
F
F
N
D
M
F
R
D
A
----
V
K
G
N
T
F
H
L
------
K
------
A
T
G
F
A
L
G
N
G
E
---------------
S
A
--------------
Q
A
-------------------
V
M
H
----
G
I
A
--------------------
G
-------------------------
S
-------------------------
S
G
WKALA
P
I
---
V
P
E
-----
P
S
Q
S
I
N
Y
V
E
S
H
D
N
H
T
F
W
D
K
M
S
F
A
L
P
Q
E
--------------------------------------------------
N
D
S
R
K
R
S
R
Q
R
L
A
V
A
I
I
L
L
A
Q
G
V
P
F
I
H
S
G
Q
E
F
F
R
T
K
Q
G
V
----------------------------------
E
N
S
Y
Q
S
S
D
S
I
N
Q
L
D
W
D
R
R
E
T
F
-------------------------------------------------------------
K
E
D
V
H
Y
I
R
R
L
I
S
L
R
K
A
H
P
A
F
R
L
R
S
A
A
D
I
Q
-
R
H
L
E
C
L
T
-------------
L
K
E
H
L
I
A
Y
R
L
Y
D
L
------------
D
EVDE
W
----
K
D
I
I
V
I
H
H
A
S
P
D
S
V
E
W
R
L
P
N
----
D
I
P
Y
R
---
L
L
C
D
P
S
G
F
Q
E
D
-
P
----------------------
T
E
I
K
K
T
V
A
V
N
G
I
G
T
V
I
L
Y
L
A
S
---------------------------------------------------------------------------------------------------------------------------------
88
HHSearch
49.09
23%
3
- C2 -
-
2WSK
-
GLGX_ECOLI
A:
[7-656]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
K
---
P
A
-
P
L
G
A
H
Y
D
G
-
Q
-
G
V
N
F
T
L
F
S
A
H
A
E
R
V
E
L
C
V
F
D
A
N
G
Q
-----
E
H
R
Y
D
L
P
-
G
---
H
-
S
G
D
I
W
H
G
Y
L
P
D
-------
A
R
P
G
L
R
Y
G
Y
R
V
H
G
P
-------------
W
QPAEG
H
R
F
N
P
------
A
K
L
L
I
D
P
C
A
R
Q
I
D
G
E
F
K
D
N
P
LLHAG
H
N
-
E
-
P
DYRDN
A
---
A
I
A
P
-------
K
C
V
V
V
V
D
----
H
Y
---
D
W
E
D
D
--
A
P
P
-
R
----
T
P
W
G
S
T
I
I
Y
E
A
H
V
K
G
L
T
---
Y
L
H
P
E
I
---
P
V
E
--------
I
R
G
T
Y
K
-----------
A
L
-------
G
-------
H
P
V
M
-----------
I
N
Y
L
K
Q
L
G
I
T
A
L
E
L
L
P
V
A
Q
F
A
S
E
P
R
L
Q
-------------------------------------------------------------------------------
R
M
G
L
S
N
Y
W
G
Y
N
P
V
A
M
F
A
L
H
P
A
Y
A
C
S
P
------
E
T
A
L
D
E
F
R
D
A
I
K
A
L
H
K
-
A
G
I
E
V
I
L
D
I
V
L
N
H
S
--
A
E
--
L
DLD
G
------
P
L
F
S
---
L
R
G
I
D
N
R
S
Y
Y
W
I
R
E
-
D
G
D
Y
H
N
W
T
G
-
C
G
N
T
-
L
N
L
S
H
P
A
V
V
D
Y
A
S
A
C
L
R
Y
W
V
E
T
C
H
V
D
G
F
R
F
D
L
A
A
V
M
G
R
TP
E
--------
F
R
Q
DA
P
L
F
T
A
I
Q
N
C
P
V
--------------------------------------
L
--------
S
Q
V
K
L
I
A
E
P
W
D
I
A
P
G
G
Y
Q
---
V
----
G
--
N
F
P
P
L
F
A
E
W
N
D
H
F
R
D
A
----
A
R
R
F
W
L
---------------------
H
Y
D
L
---------------
P
L
--------------
G
A
-------------------
F
A
G
----
R
F
A
--------------------
A
-------------------------
S
-------------------------
S
D
-----
V
F
KR
N
G
R
L
-----
P
S
A
A
I
N
L
V
T
A
H
D
G
F
T
L
R
D
C
V
C
F
N
H
K
H
N
E
A
NGEENRDGTNNNYSNNHGKEG
L
G
GS
L
---------------------
D
L
V
E
R
R
R
D
S
I
H
A
L
L
T
T
L
L
L
S
Q
G
T
P
M
L
L
A
G
D
E
H
G
H
S
Q
H
G
N
N
----------------------------------
N
A
Y
C
Q
D
N
Q
L
T
W
L
D
W
S
Q
A
S
---------------------------------------------------------------
S
G
L
T
A
F
T
A
A
L
I
H
L
R
K
R
I
P
A
L
V
E
N
R
W
W
E
E
G
D
G
N
V
R
W
L
N
R
Y
A
Q
-
P
LS
T
D
E
W
Q
N
G
P
K
Q
L
Q
I
L
L
--------------------
S
----
D
R
F
L
I
A
I
N
A
T
L
E
V
T
E
I
V
L
P
A
-----
G
E
W
H
---
A
I
P
P
F
A
G
E
D
N
P
---
V
----------------------
I
T
A
V
W
Q
G
P
A
H
G
L
C
V
F
Q
------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
48.39
28%
30
* C3 *
-
2E8Y
1
PULA_BACSU
A:
[97-636]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
D
E
F
---
Y
Y
---
D
G
-
E
L
G
A
V
Y
T
A
D
--
H
T
V
F
K
V
W
A
P
A
A
T
S
A
A
V
K
L
---
S
H
P
N
K
--
S
G
R
T
F
Q
M
T
-
R
---
L
-
E
K
G
V
Y
A
V
T
V
T
G
-------
D
L
H
G
Y
E
Y
L
F
C
I
C
N
N
-------------
S
---------
E
------
W
M
E
T
V
D
Q
Y
A
K
A
V
T
V
-
N
G
E
K
G
-----
V
V
-
L
-
R
-----
P
---
D
Q
M
K
-------
W
T
A
P
-
L
K
P
-------------------
F
----
S
H
P
V
D
A
V
I
Y
E
T
H
L
R
D
F
S
IHE
N
-
S
G
M
I
N
K
--------------
G
K
Y
L
-----------
A
L
-------
T
-------
E
--
T
DTQTANGSSSG
L
A
Y
V
K
E
L
G
V
T
H
V
E
L
L
P
V
N
D
F
A
G
V
D
E
E
K
P
L
D
--------------------------------------------------------------------------------
A
Y
N
W
G
Y
N
P
L
H
F
F
A
P
E
G
S
Y
A
S
N
P
H
---
D
P
Q
T
R
K
T
E
L
K
Q
M
I
N
T
L
H
Q
-
H
G
L
R
V
I
L
D
V
V
F
N
H
V
--
Y
K
--
R
---
E
NS----
P
------
F
E
K
T
V
P
G
Y
F
F
R
H
D
E
-
C
G
K
P
S
N
G
T
G
V
G
N
-
D
-
I
A
S
E
R
R
M
A
R
K
F
I
A
D
C
V
V
Y
W
L
E
E
Y
N
V
D
G
F
R
F
D
L
L
G
I
L
D
I
--
D
--------
T
V
L
--
Y
M
K
E
K
A
T
--
K
A
--------------------------------------
K
--------
P
G
I
L
L
F
G
E
G
W
-
D
L
A
T
P
L
P
H
E
Q
K
A
A
L
A
N
-
A
P
R
M
P
G
I
G
F
F
N
D
M
F
R
D
A
----
V
K
G
N
T
F
H
L
------
K
------
A
T
G
F
A
L
G
N
G
E
---------------
S
A
--------------
Q
A
-------------------
V
M
H
----
G
-
I
--------------------
A
-------------------------
G
-------------------------
S
S
-----
G
W
--
K
A
L
A
PIVPE
P
S
Q
S
I
N
Y
V
E
S
H
D
N
H
T
F
W
D
K
M
S
F
A
L
P
Q
--------------------------------------------------
E
N
D
S
R
K
R
S
R
Q
R
L
A
V
A
I
I
L
L
A
Q
G
V
P
F
I
H
S
G
Q
E
F
F
R
T
K
Q
----------------------------------
G
V
E
N
S
Y
Q
S
S
D
S
I
N
Q
L
D
W
D
R
R
---------------
E
------------
T
F
---------------
K
----------------
E
D
V
H
---
Y
I
R
R
L
I
S
L
R
K
A
H
P
A
F
R
L
R
S
A
A
D
I
Q
-
R
H
L
E
C
L
T
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
48.33
28%
30
- C3 -
-
2E8Z
2
PULA_BACSU
A:
[97-636]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
D
E
F
---
Y
Y
---
D
G
-
E
L
G
A
V
Y
T
A
D
--
H
T
V
F
K
V
W
A
P
A
A
T
S
A
A
V
K
L
---
S
H
P
N
K
--
S
G
R
T
F
Q
M
T
-
R
---
L
-
E
K
G
V
Y
A
V
T
V
T
G
-------
D
L
H
G
Y
E
Y
L
F
C
I
C
N
N
-------------
S
---------
E
------
W
M
E
T
V
D
Q
Y
A
K
A
V
T
V
-
N
G
E
K
G
-----
V
V
-
L
-
R
-----
P
---
D
Q
M
K
-------
W
T
A
P
-
L
K
P
-------------------
F
----
S
H
P
V
D
A
V
I
Y
E
T
H
L
R
D
F
S
IHE
N
-
S
G
M
I
N
K
--------------
G
K
Y
L
-----------
A
L
-------
T
-------
E
--
T
DTQTANGSSSG
L
A
Y
V
K
E
L
G
V
T
H
V
E
L
L
P
V
N
D
F
A
G
V
D
E
E
K
P
L
D
--------------------------------------------------------------------------------
A
Y
N
W
G
Y
N
P
L
H
F
F
A
P
E
G
S
Y
A
S
N
P
H
---
D
P
Q
T
R
K
T
E
L
K
Q
M
I
N
T
L
H
Q
-
H
G
L
R
V
I
L
D
V
V
F
N
H
V
--
Y
K
--
R
---
E
NS----
P
------
F
E
K
T
V
P
G
Y
F
F
R
H
D
E
-
C
G
K
P
S
N
G
T
G
V
G
N
-
D
-
I
A
S
E
R
R
M
A
R
K
F
I
A
D
C
V
V
Y
W
L
E
E
Y
N
V
D
G
F
R
F
D
L
L
G
I
L
D
I
--
D
--------
T
V
L
--
Y
M
K
E
K
A
T
--
K
A
--------------------------------------
K
--------
P
G
I
L
L
F
G
E
G
W
-
D
L
A
T
P
L
P
H
E
Q
K
A
A
L
A
N
-
A
P
R
M
P
G
I
G
F
F
N
D
M
F
R
D
A
----
V
K
G
N
T
F
H
L
------
K
------
A
T
G
F
A
L
G
N
G
E
---------------
S
A
--------------
Q
A
-------------------
V
M
H
----
G
-
I
--------------------
A
-------------------------
G
-------------------------
S
S
-----
G
W
--
K
A
L
A
PIVPE
P
S
Q
S
I
N
Y
V
E
S
H
D
N
H
T
F
W
D
K
M
S
F
A
L
P
Q
--------------------------------------------------
E
N
D
S
R
K
R
S
R
Q
R
L
A
V
A
I
I
L
L
A
Q
G
V
P
F
I
H
S
G
Q
E
F
F
R
T
K
Q
----------------------------------
G
V
E
N
S
Y
Q
S
S
D
S
I
N
Q
L
D
W
D
R
R
---------------
E
------------
T
F
---------------
K
----------------
E
D
V
H
---
Y
I
R
R
L
I
S
L
R
K
A
H
P
A
F
R
L
R
S
A
A
D
I
Q
-
R
H
L
E
C
L
T
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
85
HHSearch
48.29
23%
19
- C2 -
-
4OKD
4
?
A:
[56-834]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
A
L
T
---
G
R
---
P
A
-
P
L
G
A
S
I
D
A
D
T
G
A
I
N
F
S
V
F
S
S
S
A
E
S
V
S
L
V
L
F
T
E
A
D
L
N
A
GR
A
T
F
E
I
P
L
D
-
P
YVN
R
-
T
G
D
V
W
H
I
M
L
P
D
-------
L
R
D
D
L
L
Y
G
Y
R
V
E
G
V
H
QEEDKDYPG
M
R
H
D
---------
K
------
R
R
V
V
L
D
P
Y
A
V
A
V
L
N
R
R
R
W
G
Q
-----
M
G
P
N
L
P
-----
Y
GEE
G
V
L
G
VMPTW
P
Q
A
A
A
A
-
L
P
A
A
--
R
G
S
A
F
D
W
E
G
D
--
T
P
L
-
N
----
L
P
M
E
S
L
V
I
Y
E
A
H
V
R
G
F
T
---
A
-
H
A
S
S
G
V
---
A
--------
A
P
G
T
Y
A
-----------
G
M
-------
V
-------
E
--
R
-----------
L
D
Y
L
K
S
L
G
V
N
A
I
E
L
L
P
V
F
E
F
N
E
L
E
Y
Y
S
Q
I
P
--------------------------------------------------------------------------
G
S
D
Q
Y
R
F
N
F
W
G
Y
S
T
V
N
Y
F
S
P
M
G
R
F
S
A
A
V
G
Q
GA
P
A
R
A
S
C
D
E
F
K
Q
L
V
K
E
C
H
R
-
R
G
I
E
V
I
L
D
V
V
F
N
H
T
--
A
E
--
G
---
N
------
E
R
G
P
T
I
S
F
R
G
L
D
N
R
V
Y
Y
M
L
A
P
-
G
G
E
Y
Y
N
Y
S
G
-
C
G
N
T
-
L
N
C
N
Q
P
V
V
R
Q
F
I
L
D
C
L
K
H
W
V
T
E
Y
H
V
D
G
F
R
F
D
L
A
S
I
L
T
R
--
A
H
S
A
W
H
P
Q
Q
Y
D
Q
--
E
T
G
Q
R
V
A
--
M
S
SGGAIVTAEGIMTDGAGVPTGYPLADP
P
L
V
E
S
I
S
E
DPV
L
--------
R
N
T
K
M
I
A
E
A
W
D
C
D
G
L
N
Q
---
V
G
A
F
P
-
H
Y
-
G
--
G
R
W
S
E
W
N
G
K
F
R
D
V
V
R
N
F
I
K
G
T
D
G
P
-------
W
------
A
G
D
F
A
S
A
I
C
G
---------------
S
P
--------------
N
I
-------------------
Y
A
N
----
N
T
P
--------------------
H
-------------------------
E
TDWWANNGG----------------
R
Q
-----
W
K
--
G
G
R
G
-----
P
H
A
S
I
N
F
V
A
A
H
D
G
F
T
L
A
D
M
V
A
Y
N
N
K
H
N
E
A
---------------------
N
G
ENNRDGEQHNNSWNCGEEGPTTK
W
E
V
N
R
L
R
Q
R
Q
M
R
N
L
T
G
A
L
L
L
S
C
G
V
P
M
I
N
M
G
D
E
Y
G
H
S
K
N
G
N
N
----------------------------------
N
T
Y
C
H
D
S
E
L
N
Y
L
R
W
D
Q
L
A
E
D
------------------------------------------------------------
P
H
G
F
N
R
F
V
R
L
L
I
H
F
R
R
A
T
P
A
L
Q
R
T
T
F
V
N
D
--
K
D
I
Q
W
H
G
E
L
P
N
T
P
----
D
W
T
D
T
S
R
L
V
A
F
T
L
H
D
G
------------
K
----
G
----
G
G
L
Y
V
A
F
N
T
S
H
L
P
K
L
L
Q
L
P
K
W
G
--
G
R
V
W
Q
---
P
L
V
D
T
S
K
V
A
P
Y
-
D
F
L
AVDG
V
L
S
A
E
D
V
A
A
A
R
R
Q
M
A
M
W
T
A
D
H
T
Y
P
V
L
P
W
S
C
I
V
L
Q
S
A
P
E
D
P
A
-----------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
48.09
28%
30
- C3 -
-
2E9B
3
PULA_BACSU
A:
[97-636]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
D
E
F
---
Y
Y
---
D
G
-
E
L
G
A
V
Y
T
A
D
--
H
T
V
F
K
V
W
A
P
A
A
T
S
A
A
V
K
L
---
S
H
P
N
K
--
S
G
R
T
F
Q
M
T
-
R
---
L
-
E
K
G
V
Y
A
V
T
V
T
G
-------
D
L
H
G
Y
E
Y
L
F
C
I
C
N
N
-------------
S
---------
E
------
W
M
E
T
V
D
Q
Y
A
K
A
V
T
V
-
N
G
E
K
G
-----
V
V
-
L
-
R
-----
P
---
D
Q
M
K
-------
W
T
A
P
-
L
K
P
-------------------
F
----
S
H
P
V
D
A
V
I
Y
E
T
H
L
R
D
F
S
IHE
N
-
S
G
M
I
N
K
--------------
G
K
Y
L
-----------
A
L
-------
T
-------
E
--
T
DTQTANG
S
S
S
G
L
A
Y
V
K
E
L
G
V
T
H
V
E
L
L
P
V
N
D
F
A
G
V
D
E
E
K
P
L
D
--------------------------------------------------------------------------------
A
Y
N
W
G
Y
N
P
L
H
F
F
A
P
E
G
S
Y
A
S
N
P
H
---
D
P
Q
T
R
K
T
E
L
K
Q
M
I
N
T
L
H
Q
-
H
G
L
R
V
I
L
D
V
V
F
N
H
V
--
Y
K
--
R
---
E
NS----
P
------
F
E
K
T
V
P
G
Y
F
F
R
H
D
E
-
C
G
K
P
S
N
G
T
G
V
G
N
-
D
-
I
A
S
E
R
R
M
A
R
K
F
I
A
D
C
V
V
Y
W
L
E
E
Y
N
V
D
G
F
R
F
D
L
L
G
I
L
D
I
--
D
--------
T
V
L
--
Y
M
K
E
K
A
T
--
K
A
--------------------------------------
K
--------
P
G
I
L
L
F
G
E
G
W
-
D
L
A
T
P
L
P
H
E
Q
K
A
A
L
A
N
-
A
P
R
M
P
G
I
G
F
F
N
D
M
F
R
D
A
----
V
K
G
N
T
F
H
L
------
K
------
A
T
G
F
A
L
G
N
G
E
---------------
S
A
--------------
Q
A
-------------------
V
M
H
----
G
-
I
--------------------
A
-------------------------
G
-------------------------
S
S
-----
G
W
--
K
A
L
A
PIVPE
P
S
Q
S
I
N
Y
V
E
S
H
D
N
H
T
F
W
D
K
M
S
F
A
L
P
Q
--------------------------------------------------
E
N
D
S
R
K
R
S
R
Q
R
L
A
V
A
I
I
L
L
A
Q
G
V
P
F
I
H
S
G
Q
E
F
F
R
T
K
Q
----------------------------------
G
V
E
N
S
Y
Q
S
S
D
S
I
N
Q
L
D
W
D
R
R
---------------
E
------------
T
F
---------------
K
----------------
E
D
V
H
---
Y
I
R
R
L
I
S
L
R
K
A
H
P
A
F
R
L
R
S
A
A
D
I
Q
-
R
H
L
E
C
L
T
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------