@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : spr0314: (2017-12-19 )
MSRRFKKSRSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAFRYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNRLNATSNYSEYSLSVAVLADSEIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLTVNQSSSYLAAYKSLIAGETKAIVLNSVFENIIELEYPDYASKIKKIYTKGFTKKVEAPKTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADGGNNQKDKLTHAGIYGVDSSIHTFSESRWTFPIYIISNICLLYNT
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130--.-------.--------.......140..-.....150.....----..160.....--..170.......180.......190.......200.......210.......220.......230.......---240.......250.......260.......270......----.280.......290........300-....-...310.......320--------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MS
R
R
F
K
K
S
R
S
Q
K
V
K
R
S
V
N
I
V
L
L
T
I
Y
L
L
L
V
C
F
L
L
F
L
I
F
K
Y
N
I
L
A
F
R
Y
L
N
L
V
V
T
A
L
V
L
L
V
A
L
V
G
L
L
L
I
I
YKKAE
K
F
T
I
F
L
L
V
F
S
I
L
V
S
S
V
S
L
F
A
V
Q
Q
F
V
G
L
T
NRLNATSNYS
E
Y
S
L
S
V
A
V
L
AD
S
E
I
E
N
V
T
Q
L
----
T
-------
S
--------VTAPTGT
D
N
E
N
I
-
Q
K
L
L
A
D
I
KSSQNT----
D
L
T
VNQS
S
S
Y
--
L
A
A
Y
K
S
L
IAGETK
A
I
V
L
N
S
V
F
E
N
I
I
ELEYP
D
Y
A
S
K
I
K
K
I
Y
T
KGFTKKVEAPKTSKN
Q
S
F
N
I
Y
V
SGIDTYGPI---SSVSRS
D
V
N
I
L
M
T
VNRDT
K
K
I
L
L
TTTPR
D
A
Y
V
P
IADGGN----NQKDKLTHAGIY-GVDSSIHTFSES-
R
W
T
F
-
P
I
Y
I
IS
N
I
C
L
L
YNT----------------------------------------------------------------------------------------------------------------------------------------------------------------
44
Fugue
85.11
90%
-69
* C2 *
-
3TEL
4
?
A:
[14-385]
-------------------------------------------------------------------------------------------------------------
S
E
Y
S
L
S
V
A
V
L
A
D
S
E
I
E
N
V
T
Q
L
----
T
-------
S
--------
V
T
A
P
T
G
T
D
N
E
N
I
-
Q
K
L
L
A
D
I
K
S
S
Q
N
T
----
D
L
T
V
N
Q
S
S
S
Y
--
L
A
A
Y
K
S
L
I
A
G
E
T
K
A
I
V
L
N
S
V
F
E
N
I
I
E
L
E
Y
P
D
Y
A
S
K
I
K
K
I
Y
T
K
G
F
T
K
K
V
E
A
P
K
T
S
K
N
Q
S
F
N
I
Y
V
S
G
I
D
T
Y
G
P
I
---
S
S
V
S
R
S
D
V
N
I
L
M
T
V
N
R
D
T
K
K
I
L
L
T
T
T
P
A
D
A
Y
V
P
I
A
D
G
G
N
----
N
Q
K
D
K
L
T
H
A
G
I
Y
-
G
V
D
S
S
I
H
T
L
E
N
L
Y
G
V
D
I
-
N
Y
Y
V
R
L
N
F
T
S
F
L
K
M
I
D
L
L
G
G
V
D
V
H
N
D
Q
E
F
S
A
LHGK
F
H
F
P
V
G
N
V
H
L
D
S
E
Q
A
L
G
F
V
R
ERYSLADG
D
R
D
R
G
R
N
Q
Q
K
V
I
V
A
I
L
Q
K
L
T
S
T
E
A
L
K
N
Y
S
T
I
I
N
S
L
QDSIQTNVP
L
E
T
M
I
N
L
V
N
A
Q
L
E
S
G
G
N
Y
K
V
N
S
Q
D
L
K
G
T
G
R
MDLPSYAMPD
S
N
L
Y
V
M
E
I
D
D
S
S
L
A
V
V
K
A
A
I
Q
D
V
M
E
GR
55
HHSearch
72.35
91%
-67
- C2 -
-
4DE8
2
?
A:
[14-224]
--------------------------------------------------------------------------------------------------------------
E
Y
S
L
S
V
A
V
L
A
D
S
E
I
E
N
V
T
Q
L
----
T
-------
S
--------
V
T
A
P
T
G
T
D
N
E
N
I
-
Q
K
L
L
A
D
I
K
S
S
Q
N
T
----
D
L
T
V
N
Q
S
S
S
Y
--
L
A
A
Y
K
S
L
I
A
G
E
T
K
A
I
V
L
N
S
V
F
E
N
I
I
E
L
E
Y
P
D
Y
A
S
K
I
K
K
I
Y
T
K
G
F
T
K
K
V
E
A
P
K
T
S
K
N
Q
S
F
N
I
Y
V
S
G
I
D
T
Y
G
P
I
---
S
S
V
S
R
S
D
V
N
I
L
M
T
V
N
R
D
T
K
K
I
L
L
T
T
T
P
A
D
A
Y
V
P
I
A
D
G
G
N
----
N
Q
K
D
K
L
T
H
A
G
I
Y
-
G
V
D
S
S
I
H
T
L
E
N
L
-
Y
G
V
D
I
N
Y
Y
V
R
L
N
F
T
S
F
L
K
M
----------------------------------------------------------------------------------------------------------------------------------------------------------------
54
HHSearch
71.82
91%
-70
- C2 -
-
2XXP
3
?
A:
[15-225]
--------------------------------------------------------------------------------------------------------------
E
Y
S
L
S
V
A
V
L
A
D
S
E
I
E
N
V
T
Q
L
----
T
-------
S
--------
V
T
A
P
T
G
T
D
N
E
N
I
-
Q
K
L
L
A
D
I
K
S
S
Q
N
T
----
D
L
T
V
N
Q
S
S
S
Y
--
L
A
A
Y
K
S
L
I
A
G
E
T
K
A
I
V
L
N
S
V
F
E
N
I
I
E
L
E
Y
P
D
Y
A
S
K
I
K
K
I
Y
T
K
G
F
T
K
K
V
E
A
P
K
T
S
K
N
Q
S
F
N
I
Y
V
S
G
I
D
T
Y
G
P
I
---
S
S
V
S
R
S
D
V
N
I
L
M
T
V
N
R
D
T
K
K
I
L
L
T
T
T
P
R
D
A
Y
V
P
I
A
D
G
G
N
----
N
Q
K
D
K
L
T
H
A
G
I
Y
-
G
V
D
S
S
I
H
T
L
E
N
L
-
Y
G
V
D
I
N
Y
Y
V
R
L
N
F
T
S
F
L
K
M
----------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
69.18
99%
-68
- C2 -
-
3TFL
2
?
A:
[14-203]
-------------------------------------------------------------------------------------------------------------
S
E
Y
S
L
S
V
A
V
L
A
D
S
E
I
E
N
V
T
Q
L
----
T
-------
S
--------
V
T
A
P
T
G
T
D
N
E
N
I
-
Q
K
L
L
A
D
I
K
S
S
Q
N
T
----
D
L
T
V
N
Q
S
S
S
Y
--
L
A
A
Y
K
S
L
I
A
G
E
T
K
A
I
V
L
N
S
V
F
E
N
I
I
E
L
E
Y
P
D
Y
A
S
K
I
K
K
I
Y
T
K
G
F
T
K
K
V
E
A
P
K
T
S
K
N
Q
S
F
N
I
Y
V
S
G
I
D
T
Y
G
P
I
---
S
S
V
S
R
S
D
V
N
I
L
M
T
V
N
R
D
T
K
K
I
L
L
T
T
T
P
R
D
A
Y
V
P
I
A
D
G
G
N
----
N
Q
K
D
K
L
T
H
A
G
I
Y
-
G
V
D
S
S
I
H
T
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
68.86
99%
-66
- C2 -
-
3TEP
4
?
A:
[14-203]
-------------------------------------------------------------------------------------------------------------
S
E
Y
S
L
S
V
A
V
L
A
D
S
E
I
E
N
V
T
Q
L
----
T
-------
S
--------
V
T
A
P
T
G
T
D
N
E
N
I
-
Q
K
L
L
A
D
I
K
S
S
Q
N
T
----
D
L
T
V
N
Q
S
S
S
Y
--
L
A
A
Y
K
S
L
I
A
G
E
T
K
A
I
V
L
N
S
V
F
E
N
I
I
E
L
E
Y
P
D
Y
A
S
K
I
K
K
I
Y
T
K
G
F
T
K
K
V
E
A
P
K
T
S
K
N
Q
S
F
N
I
Y
V
S
G
I
D
T
Y
G
P
I
---
S
S
V
S
R
S
D
V
N
I
L
M
T
V
N
R
D
T
K
K
I
L
L
T
T
T
P
R
D
A
Y
V
P
I
A
D
G
G
N
----
N
Q
K
D
K
L
T
H
A
G
I
Y
-
G
V
D
S
S
I
H
T
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
68.72
98%
-70
- C2 -
-
3TEL
1
?
A:
[14-203]
-------------------------------------------------------------------------------------------------------------
S
E
Y
S
L
S
V
A
V
L
A
D
S
E
I
E
N
V
T
Q
L
----
T
-------
S
--------
V
T
A
P
T
G
T
D
N
E
N
I
-
Q
K
L
L
A
D
I
K
S
S
Q
N
T
----
D
L
T
V
N
Q
S
S
S
Y
--
L
A
A
Y
K
S
L
I
A
G
E
T
K
A
I
V
L
N
S
V
F
E
N
I
I
E
L
E
Y
P
D
Y
A
S
K
I
K
K
I
Y
T
K
G
F
T
K
K
V
E
A
P
K
T
S
K
N
Q
S
F
N
I
Y
V
S
G
I
D
T
Y
G
P
I
---
S
S
V
S
R
S
D
V
N
I
L
M
T
V
N
R
D
T
K
K
I
L
L
T
T
T
P
A
D
A
Y
V
P
I
A
D
G
G
N
----
N
Q
K
D
K
L
T
H
A
G
I
Y
-
G
V
D
S
S
I
H
T
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
68.39
98%
-67
- C2 -
-
2XXQ
3
?
A:
[14-203]
-------------------------------------------------------------------------------------------------------------
S
E
Y
S
L
S
V
A
V
L
A
D
S
E
I
E
N
V
T
Q
L
----
T
-------
S
--------
V
T
A
P
T
G
T
D
N
E
N
I
-
Q
K
L
L
A
D
I
K
S
S
Q
N
T
----
D
L
T
V
N
Q
S
S
S
Y
--
L
A
A
Y
K
S
L
I
A
G
E
T
K
A
I
V
L
N
S
V
F
E
N
I
I
E
L
E
Y
P
D
Y
A
S
K
I
K
K
I
Y
T
K
G
F
T
K
K
V
E
A
P
K
T
S
K
N
Q
S
F
N
I
Y
V
S
G
I
D
T
Y
G
P
I
---
S
S
V
S
R
S
D
V
N
I
L
M
T
V
N
R
D
T
K
K
I
L
L
T
T
T
P
A
D
A
Y
V
P
I
A
D
G
G
N
----
N
Q
K
D
K
L
T
H
A
G
I
Y
-
G
V
D
S
S
I
H
T
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
67.49
99%
-67
- C2 -
-
2XXP
3
?
A:
[15-203]
--------------------------------------------------------------------------------------------------------------
E
Y
S
L
S
V
A
V
L
A
D
S
E
I
E
N
V
T
Q
L
----
T
-------
S
--------
V
T
A
P
T
G
T
D
N
E
N
I
-
Q
K
L
L
A
D
I
K
S
S
Q
N
T
----
D
L
T
V
N
Q
S
S
S
Y
--
L
A
A
Y
K
S
L
I
A
G
E
T
K
A
I
V
L
N
S
V
F
E
N
I
I
E
L
E
Y
P
D
Y
A
S
K
I
K
K
I
Y
T
K
G
F
T
K
K
V
E
A
P
K
T
S
K
N
Q
S
F
N
I
Y
V
S
G
I
D
T
Y
G
P
I
---
S
S
V
S
R
S
D
V
N
I
L
M
T
V
N
R
D
T
K
K
I
L
L
T
T
T
P
R
D
A
Y
V
P
I
A
D
G
G
N
----
N
Q
K
D
K
L
T
H
A
G
I
Y
-
G
V
D
S
S
I
H
T
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
67.48
99%
-65
- C2 -
-
4DE8
2
?
A:
[14-202]
--------------------------------------------------------------------------------------------------------------
E
Y
S
L
S
V
A
V
L
A
D
S
E
I
E
N
V
T
Q
L
----
T
-------
S
--------
V
T
A
P
T
G
T
D
N
E
N
I
-
Q
K
L
L
A
D
I
K
S
S
Q
N
T
----
D
L
T
V
N
Q
S
S
S
Y
--
L
A
A
Y
K
S
L
I
A
G
E
T
K
A
I
V
L
N
S
V
F
E
N
I
I
E
L
E
Y
P
D
Y
A
S
K
I
K
K
I
Y
T
K
G
F
T
K
K
V
E
A
P
K
T
S
K
N
Q
S
F
N
I
Y
V
S
G
I
D
T
Y
G
P
I
---
S
S
V
S
R
S
D
V
N
I
L
M
T
V
N
R
D
T
K
K
I
L
L
T
T
T
P
A
D
A
Y
V
P
I
A
D
G
G
N
----
N
Q
K
D
K
L
T
H
A
G
I
Y
-
G
V
D
S
S
I
H
T
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
56
HHSearch
38.82
28%
-306
- C2 -
-
3PE5
-
?
B:
[103-202]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
K
D
P
M
V
L
N
I
M
L
F
G
S
D
E
R
P
G
E
---
T
G
Y
G
R
S
D
T
M
M
L
L
S
I
D
N
R
N
K
K
L
K
L
T
S
F
M
R
D
T
Y
V
N
V
P
E
W
G
-------
D
T
K
L
T
H
A
Y
S
Y
G
G
P
A
L
A
I
E
T
I
E
R
N
-
F
G
I
D
I
D
R
Y
A
V
V
Y
F
D
T
F
P
G
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------
64
HHSearch
36.41
34%
-46
- C2 -
-
4DE9
1
YWTF_BACSU
A:
[22-148]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
F
D
P
G
K
D
S
F
S
V
L
L
L
G
I
D
----------
Q
A
R
S
D
A
N
V
L
V
T
F
N
R
K
E
K
T
A
K
M
L
S
I
P
R
D
A
Y
V
N
I
P
G
H
-------
G
Y
D
K
F
T
H
A
H
A
Y
G
G
V
D
L
T
V
K
T
V
E
E
M
-
L
D
I
P
V
D
Y
V
V
E
S
N
F
T
A
F
E
D
V
----------------------------------------------------------------------------------------------------------------------------------------------------------------
70
HHSearch
36.02
14%
-14
- C2 -
-
2IA4
1
?
B:
[107-188]
------------------------------------------------------------------------------------------------------------
I
F
V
V
G
T
R
L
L
T
K
K
G
G
D
I
K
D
F
A
D
L
----
K
-------
G
K
A
------
V
V
V
T
S
G
T
T
S
----
E
V
L
L
N
K
L
N
E
E
Q
K
M
----
N
M
R
I
I
S
A
K
D
H
--
G
D
S
F
R
T
L
E
S
G
R
A
V
A
F
M
M
D
D
A
L
L
A
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
69
HHSearch
35.82
14%
-14
- C2 -
-
2VHA
1
?
B:
[107-188]
------------------------------------------------------------------------------------------------------------
I
F
V
V
G
T
R
L
L
T
K
K
G
G
D
I
K
D
F
A
D
L
----
K
-------
G
KA------
V
V
V
T
S
G
T
T
S
----
E
V
L
L
N
K
L
N
E
E
Q
K
M
----
N
M
R
I
I
S
A
K
D
H
--
G
D
S
F
R
T
L
E
S
G
R
A
V
A
F
M
M
D
D
A
L
L
A
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
67
HHSearch
35.04
18%
-19
- C2 -
-
5JKQ
-
?
B:
[175-264]
-------------------------------------------------------------------------------------------------------------
I
K
H
S
N
K
I
M
I
L
K
E
Y
N
I
N
N
L
E
D
L
----
K
S
Y
I
S
K
N
E
G
L
K
------
I
A
C
L
T
E
A
N
C
N
A
----
L
K
N
I
F
----
L
D
----
K
V
T
Y
D
Y
K
S
F
S
S
Y
I
D
L
S
K
S
V
L
S
K
S
H
I
I
G
V
I
S
G
I
P
F
N
F
N
E
H
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
63
HHSearch
33.38
34%
-46
- C2 -
-
3MEJ
-
YWTF_BACSU
A:
[22-138]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
F
D
P
G
K
D
S
F
S
V
L
L
L
G
I
D
----------
Q
A
R
S
D
A
N
V
L
V
T
F
N
R
K
E
K
T
A
K
M
L
S
I
P
R
D
A
Y
V
N
I
P
G
H
-------
G
Y
D
K
F
T
H
A
H
A
Y
G
G
V
D
L
T
V
K
T
V
E
E
M
-
L
D
I
P
V
D
Y
V
V
E
S
N
F
T
A
F
E
D
V
----------------------------------------------------------------------------------------------------------------------------------------------------------------
73
HHSearch
32.78
13%
-11
- C2 -
-
2QPQ
1
?
A:
[102-189]
---------------------------------------------------------------------------------------------------------------
V
P
S
V
F
V
V
P
A
G
S
K
Y
K
T
L
G
E
L
----
M
-------
A
A
A
KQTNTQ
V
T
Y
G
S
C
G
N
G
T
P
Q
-
H
L
A
G
E
L
L
N
V
S
A
K
T
----
H
M
V
H
V
P
Y
K
G
C
--
G
P
A
L
N
D
V
L
G
S
Q
I
G
L
A
V
V
T
A
S
S
A
I
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
58
HHSearch
32.27
23%
-1
- C2 -
-
3OKZ
-
?
A:
[52-163]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
A
I
E
E
T
K
P
F
S
I
L
L
M
G
V
D
T
G
S
E
H
RKS
K
W
S
G
N
S
D
S
M
I
L
V
T
I
N
P
K
T
N
K
T
T
M
T
S
L
E
R
D
V
L
I
K
L
S
G
P
K
N
NGQT
G
V
E
A
K
L
N
A
A
Y
A
S
G
G
A
E
M
A
L
M
T
V
Q
D
L
-
L
D
I
N
V
D
Y
F
M
Q
I
N
M
Q
G
L
V
D
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------
66
HHSearch
31.71
17%
-30
- C2 -
-
3HV1
-
?
A:
[129-213]
--------------------------------------------------------------------------------------------------------------
V
N
E
Q
V
L
V
T
K
K
S
S
G
I
D
S
V
A
G
M
----
A
-------
G
K
T
------
L
G
A
Q
A
G
S
S
G
Y
D
A
F
N
A
S
P
K
I
L
K
D
V
-
V
A
----
N
Q
K
V
V
Q
Y
S
T
F
--
T
Q
A
L
I
D
L
N
S
G
R
I
D
G
L
L
I
D
R
V
Y
A
N
Y
Y
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
72
HHSearch
30.88
12%
15
- C2 -
-
3N5L
6
?
A:
[90-183]
-------------------------------------------------------------------------------------------------------------
P
G
Y
W
S
L
L
I
A
N
K
D
S
K
I
D
S
L
E
D
M
L
A
N
A
K
-------
S
L
T
------
F
G
N
G
D
P
N
S
T
S
G
Y
-
L
V
P
G
Y
Y
V
F
A
K
N
N
V
DPVK
A
F
K
R
T
L
N
S
S
H
--
E
V
N
A
L
A
V
A
N
K
Q
V
D
V
A
T
F
N
T
E
G
M
E
R
L
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
68
HHSearch
30.04
18%
-26
- C2 -
-
5JKQ
-
?
D:
[175-264]
-------------------------------------------------------------------------------------------------------------
I
K
H
S
N
K
I
M
I
L
K
E
Y
N
I
N
N
L
E
D
L
----
K
S
Y
I
S
K
N
E
G
L
K
------
I
A
C
L
T
E
A
N
C
N
A
----
L
K
N
I
F
----
L
D
----
K
V
T
Y
D
Y
K
S
F
S
S
Y
I
D
L
S
K
S
V
L
S
K
S
H
I
I
G
V
I
S
G
I
P
F
N
F
N
E
H
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------