@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : spr0408: (2017-12-21 )
MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGKSTFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENTIVAQTTVLKRERTEAEKIAKENLEKVGMGERYWQAKPKQLSGGQKQRVAIARALSMNPDAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGVIAEEGKPEDLFTNPKEDRTKEFLQRYLK
Atome Classification :
(35 SA)
.........10........----20........30........40........50........60.....-------------...-70....----------....80.........90........100.......110........120.......130---..--....--.140--........150......-.160.......170.......180-.......-190........200.......210....-...220.......230.......240....------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
M
T
Q
A
I
L
E
I
K
H
L
K
K
SYG
Q
N
E
----
V
L
K
D
I
S
L
T
V
HK
G
E
V
I
S
I
IGSSGSG
K
S
T
F
L
R
S
I
NLLETPTD
G
Q
I
L
YH
G
-------------
Q
N
V
-
L
E
KGY
D
----------
L
T
Q
Y
R
-
E
K
L
G
M
V
F
Q
S
F
N
L
F
E
N
L
N
V
L
E
N
T
I
V
A
Q
T
T
V
L
K
-RE
R
T
E
A
E
K
I
A
K
E
N
L
E
K
VGMG
E
---
R
Y
--WQAK--PKQ---LSGGQ
K
Q
R
V
A
I
A
R
ALSM-NP
D
A
I
L
FDEPTSAL
D
P
E
M
V
G
E
V
L
K
-
I
M
Q
D
L
A
Q-E-G
L
T
M
I
V
V
TH
E
M
E
F
A
R
DVS
H
R
V
I
F
M
DK-GVIAEEGKPEDLFTNPK
E
D
R
T
K
E
F
L
Q
R
YLK------
21
PsiBlast_CBE
95.40
56%
-112
- C1 -
-
3C4J
2
?
B:
[24-263]
----
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
E
----
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
-------------
I
N
L
-
K
A
K
D
T
N
----------
L
N
K
V
R
-
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
K
-
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
---
K
A
---
H
A
Y
--
P
D
S
---
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
-
V
M
K
Q
L
A
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
-
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
-------
1
PsiBlast_PDB
95.06
56%
-117
- C1 -
-
2OLJ
3
?
A:
[24-263]
----
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
E
----
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
-------------
I
N
L
-
K
A
K
D
T
N
----------
L
N
K
V
R
-
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
K
-
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
---
K
A
---
H
A
Y
--
P
D
S
---
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
-
V
M
K
Q
L
A
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
-
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
-------
3
PsiBlast_PDB
94.50
56%
-113
- C1 -
-
2OUK
-
?
A:
[24-263]
----
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
E
----
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
-------------
I
N
L
-
K
A
K
D
T
N
----------
L
N
K
V
R
-
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
K
-
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
---
K
A
---
H
A
Y
--
P
D
S
---
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
-
V
M
K
Q
L
A
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
-
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
-------
29
PsiBlast_CBE
94.37
56%
-109
- C1 -
-
2OLK
2
?
B:
[24-263]
----
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
E
----
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
-------------
I
N
L
-
K
A
K
D
T
N
----------
L
N
K
V
R
-
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
K
-
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
---
K
A
---
H
A
Y
--
P
D
S
---
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
-
V
M
K
Q
L
A
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
-
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
-------
5
PsiBlast_PDB
94.12
56%
-108
- C1 -
-
3C4J
2
?
A:
[24-263]
----
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
E
----
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
-------------
I
N
L
-
K
A
K
D
T
N
----------
L
N
K
V
R
-
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
K
-
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
---
K
A
---
H
A
Y
--
P
D
S
---
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
-
V
M
K
Q
L
A
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
-
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
-------
6
PsiBlast_PDB
93.46
56%
-103
- C1 -
-
3C41
2
?
J:
[3-242]
----
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
E
----
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
-------------
I
N
L
-
K
A
K
D
T
N
----------
L
N
K
V
R
-
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
K
-
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
---
K
A
---
H
A
Y
--
P
D
S
---
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
-
V
M
K
Q
L
A
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
-
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
-------
4
PsiBlast_PDB
93.30
56%
-108
- C1 -
-
2Q0H
3
?
A:
[24-263]
----
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
E
----
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
-------------
I
N
L
-
K
A
K
D
T
N
----------
L
N
K
V
R
-
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
K
-
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
---
K
A
---
H
A
Y
--
P
D
S
---
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
-
V
M
K
Q
L
A
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
-
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
-------
30
PsiBlast_CBE
93.04
56%
-108
- C1 -
-
2OLJ
2
?
B:
[24-263]
----
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
E
----
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
-------------
I
N
L
-
K
A
K
D
T
N
----------
L
N
K
V
R
-
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
K
-
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
---
K
A
---
H
A
Y
--
P
D
S
---
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
-
V
M
K
Q
L
A
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
-
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
-------
27
PsiBlast_CBE
92.91
56%
-110
- C1 -
-
2OLK
1
?
D:
[24-263]
----
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
E
----
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
-------------
I
N
L
-
K
A
K
D
T
N
----------
L
N
K
V
R
-
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
K
-
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
---
K
A
---
H
A
Y
--
P
D
S
---
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
-
V
M
K
Q
L
A
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
-
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
-------
2
PsiBlast_PDB
92.84
56%
-112
- C1 -
-
2OLK
1
?
A:
[24-263]
----
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
E
----
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
-------------
I
N
L
-
K
A
K
D
T
N
----------
L
N
K
V
R
-
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
K
-
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
---
K
A
---
H
A
Y
--
P
D
S
---
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
-
V
M
K
Q
L
A
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
-
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
-------
28
PsiBlast_CBE
92.53
56%
-110
- C1 -
-
2OLK
1
?
C:
[24-263]
----
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
E
----
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
-------------
I
N
L
-
K
A
K
D
T
N
----------
L
N
K
V
R
-
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
K
-
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
---
K
A
---
H
A
Y
--
P
D
S
---
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
-
V
M
K
Q
L
A
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
-
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
-------
10
PsiBlast_PDB
92.47
55%
-110
- C1 -
-
4YMV
1
?
J:
[4-240]
-------
V
N
D
V
Y
K
N
F
G
S
L
E
----
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
-------------
V
K
I
-
N
N
G
K
V
N
----------
I
N
K
V
R
-
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
L
A
P
V
K
V
K
K
-
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
---
K
K
--
D
Q
Y
---
P
I
K
---
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
-
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
-
V
M
K
Q
L
A
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
-
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
E
R
T
R
E
F
L
S
K
I
L
-------
32
PsiBlast_CBE
92.32
55%
-112
- C1 -
-
4YMU
1
?
A:
[4-240]
-------
V
N
D
V
Y
K
N
F
G
S
L
E
----
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
-------------
V
K
I
-
N
N
G
K
V
N
----------
I
N
K
V
R
-
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
L
A
P
V
K
V
K
K
-
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
---
K
K
--
D
Q
Y
---
P
I
K
---
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
-
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
-
V
M
K
Q
L
A
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
-
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
E
R
T
R
E
F
L
S
K
I
L
-------
22
PsiBlast_CBE
92.29
56%
-111
- C1 -
-
3C41
2
?
K:
[3-242]
----
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
E
----
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
-------------
I
N
L
-
K
A
K
D
T
N
----------
L
N
K
V
R
-
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
K
-
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
---
K
A
---
H
A
Y
--
P
D
S
---
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
-
V
M
K
Q
L
A
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
-
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
-------
23
PsiBlast_CBE
92.18
56%
-115
- C1 -
-
2Q0H
3
?
B:
[24-263]
----
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
E
----
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
-------------
I
N
L
-
K
A
K
D
T
N
----------
L
N
K
V
R
-
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
K
-
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
---
K
A
---
H
A
Y
--
P
D
S
---
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
-
V
M
K
Q
L
A
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
-
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
-------
31
PsiBlast_CBE
91.79
55%
-108
- C1 -
-
4YMV
1
?
A:
[4-240]
-------
V
N
D
V
Y
K
N
F
G
S
L
E
----
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
-------------
V
K
I
-
N
N
G
K
V
N
----------
I
N
K
V
R
-
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
L
A
P
V
K
V
K
K
-
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
---
K
K
--
D
Q
Y
---
P
I
K
---
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
-
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
-
V
M
K
Q
L
A
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
-
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
E
R
T
R
E
F
L
S
K
I
L
-------
8
PsiBlast_PDB
91.62
55%
-107
- C1 -
-
4YMT
-
?
J:
[4-240]
-------
V
N
D
V
Y
K
N
F
G
S
L
E
----
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
-------------
V
K
I
-
N
N
G
K
V
N
----------
I
N
K
V
R
-
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
L
A
P
V
K
V
K
K
-
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
---
K
K
--
D
Q
Y
---
P
I
K
---
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
-
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
-
V
M
K
Q
L
A
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
-
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
E
R
T
R
E
F
L
S
K
I
L
-------
7
PsiBlast_PDB
91.61
55%
-109
- C1 -
-
4YMS
-
?
J:
[4-240]
-------
V
N
D
V
Y
K
N
F
G
S
L
E
----
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
-------------
V
K
I
-
N
N
G
K
V
N
----------
I
N
K
V
R
-
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
L
A
P
V
K
V
K
K
-
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
---
K
K
--
D
Q
Y
---
P
I
K
---
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
-
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
-
V
M
K
Q
L
A
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
-
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
E
R
T
R
E
F
L
S
K
I
L
-------
11
PsiBlast_PDB
91.51
55%
-107
- C1 -
-
4YMW
-
?
J:
[4-240]
-------
V
N
D
V
Y
K
N
F
G
S
L
E
----
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
-------------
V
K
I
-
N
N
G
K
V
N
----------
I
N
K
V
R
-
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
L
A
P
V
K
V
K
K
-
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
---
K
K
--
D
Q
Y
---
P
I
K
---
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
-
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
-
V
M
K
Q
L
A
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
-
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
E
R
T
R
E
F
L
S
K
I
L
-------
9
PsiBlast_PDB
90.62
55%
-108
- C1 -
-
4YMU
1
?
J:
[4-240]
-------
V
N
D
V
Y
K
N
F
G
S
L
E
----
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
-------------
V
K
I
-
N
N
G
K
V
N
----------
I
N
K
V
R
-
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
L
A
P
V
K
V
K
K
-
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
---
K
K
--
D
Q
Y
---
P
I
K
---
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
-
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
-
V
M
K
Q
L
A
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
-
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
E
R
T
R
E
F
L
S
K
I
L
-------
14
PsiBlast_PDB
85.48
54%
-6
- C1 -
-
1B0U
1
HISP_SALTY
A:
[5-258]
---
N
K
L
H
V
I
D
L
H
K
R
Y
G
G
H
E
----
V
L
K
G
V
S
L
Q
A
R
A
G
D
V
I
S
I
I
G
S
S
G
S
G
K
S
T
F
L
R
C
I
N
F
L
E
K
P
S
E
G
A
I
I
V
N
G
-------------
Q
N
I
N
L
V
R
D
K
D
GQLKVAD
K
N
Q
L
R
L
L
R
-
T
R
L
T
M
V
F
Q
H
F
N
L
W
S
H
M
T
V
L
E
N
V
M
E
A
P
I
Q
V
L
G
-
L
S
K
H
D
A
R
E
R
A
L
K
Y
L
A
K
V
G
I
D
E
---
R
A
--
Q
G
K
Y
--
P
V
H
---
L
S
G
G
Q
Q
Q
R
V
S
I
A
R
A
L
A
M
-
E
P
D
V
L
L
F
D
E
P
T
S
A
L
D
P
E
L
V
G
E
V
L
R
-
I
M
Q
Q
L
A
E
-
E
-
G
K
T
M
V
V
V
T
H
E
M
G
F
A
R
H
V
S
S
H
V
I
F
L
H
Q
-
G
K
I
E
E
E
G
D
P
E
Q
V
F
G
N
P
Q
S
P
R
L
Q
Q
F
L
K
G
S
L
K
------
12
PsiBlast_PDB
83.88
56%
-23
- C1 -
-
4U00
1
?
A:
[3-242]
---
P
I
I
R
I
R
N
L
H
K
W
F
G
P
L
H
----
V
L
K
G
I
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
R
L
E
D
F
Q
E
G
E
V
V
V
D
G
-------------
L
S
V
--
K
D
D
R
A
----------
L
R
E
I
R
-
R
E
V
G
M
V
F
Q
Q
F
N
L
F
P
H
M
T
V
L
E
N
V
T
L
A
P
M
R
V
R
R
-
W
P
R
E
K
A
E
K
K
A
L
E
L
L
E
R
V
G
I
L
D
--------
Q
A
R
KY
P
A
Q
---
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
D
-
V
M
R
D
L
A
Q
-
G
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
A
D
R
V
V
F
M
D
G
-
G
Q
I
V
E
E
G
R
P
E
E
I
F
T
R
P
K
E
E
R
T
R
S
F
L
Q
R
V
L
-------
161
Fugue
74.69
54%
36
- C1 -
-
1B0U
1
HISP_SALTY
A:
[5-261]
---
N
K
L
H
V
I
D
L
H
K
R
Y
G
G
--HEV-
L
K
-
G
V
S
L
Q
A
R
A
G
D
V
I
S
I
I
G
S
S
G
S
G
K
S
T
F
L
R
C
I
N
F
L
E
K
P
S
E
G
A
I
I
V
N
G
QNI
N
L
V
R
D
KDGQL
K
V
A
-
D
K
N
Q
L
R
----------
L
L
R
T
--
R
-
L
T
M
V
F
Q
H
F
N
L
W
S
H
M
T
V
L
E
N
V
M
E
A
P
I
Q
V
L
-G
L
S
K
H
D
A
R
E
R
A
L
K
Y
L
A
K
V
G
I
D
E
---
R
A
QG--
K
Y
--
P
V
H
---
L
S
G
G
Q
Q
Q
R
V
S
I
A
R
A
L
A
M
E-
P
D
V
L
L
F
D
E
P
T
S
A
L
D
P
E
L
V
G
E
V
L
R
-
I
M
Q
Q
L
A
E
-
E
-
G
K
T
M
V
V
V
T
H
E
M
G
F
A
R
H
V
S
S
H
V
I
F
L
H
-Q
G
K
I
E
E
E
G
D
P
E
Q
V
F
G
N
P
-
Q
S
--
P
R
L
Q
Q
F
L
K
G
S
L
K
KLE
140
HHSearch
65.04
35%
-102
- C1 -
-
3FVQ
2
FBPC_NEIG1
B:
[2-231]
--
T
A
A
L
H
I
G
H
L
S
K
S
F
Q
N
T
P
----
V
L
N
D
I
S
L
S
L
D
P
G
E
I
L
F
I
I
G
A
S
G
C
G
K
T
T
L
L
R
C
L
A
G
F
E
Q
P
D
S
G
E
I
S
L
S
G
-------------
K
T
I
-
F
S
K
N
T
N
----------
L
P
V
R
E
-
R
R
L
G
Y
L
V
Q
E
G
V
L
F
P
H
L
T
V
Y
R
N
I
A
Y
G
L
G
N
G
K
G
--
R
T
A
Q
E
R
Q
R
I
E
A
M
L
E
L
T
G
I
S
E
---
L
A
---
G
R
Y
--
P
H
E
---
L
S
G
G
Q
Q
Q
R
A
A
L
A
R
A
L
A
P
-
D
P
E
L
I
L
L
D
E
P
F
S
A
L
D
E
Q
L
R
R
Q
I
R
E
-
D
M
I
A
A
L
R
A
N
-
G
K
S
A
V
F
V
S
H
D
R
E
E
A
L
Q
Y
A
D
R
I
A
V
M
K
Q
-
G
R
I
L
Q
T
A
S
P
H
E
L
Y
R
Q
P
A
-------------------
112
PsiBlast_CBE
62.43
36%
-55
- C1 -
-
3FVQ
2
FBPC_NEIG1
B:
[3-232]
---
A
A
L
H
I
G
H
L
S
K
S
F
Q
N
T
P
----
V
L
N
D
I
S
L
S
L
D
P
G
E
I
L
F
I
I
G
A
S
G
C
G
K
T
T
L
L
R
C
L
A
G
F
E
Q
P
D
S
G
E
I
S
L
S
G
-------------
K
T
I
-
F
S
K
N
T
N
----------
L
P
V
R
E
-
R
R
L
G
Y
L
V
Q
E
G
V
L
F
P
H
L
T
V
Y
R
N
I
A
Y
G
L
G
N
G
K
G
-
R
T
A
Q
E
R
Q
R
I
-
E
A
M
L
E
L
T
G
I
S
E
LAG
R
Y
--------
P
H
E
---
L
S
G
G
Q
Q
Q
R
A
A
L
A
R
A
L
A
P
-
D
P
E
L
I
L
L
D
E
P
F
S
A
L
D
E
Q
L
R
R
Q
I
R
E
D
M
I
A
A
L
R
A
-
N
-
G
K
S
A
V
F
V
S
H
D
R
E
E
A
L
Q
Y
A
D
R
I
A
V
M
K
Q
-
G
R
I
L
Q
T
A
S
P
H
E
L
Y
R
Q
P
A
D
------------------
113
PsiBlast_CBE
62.29
36%
-55
- C1 -
-
3FVQ
2
FBPC_NEIG1
A:
[3-237]
---
A
A
L
H
I
G
H
L
S
K
S
F
Q
N
T
P
----
V
L
N
D
I
S
L
S
L
D
P
G
E
I
L
F
I
I
G
A
S
G
C
G
K
T
T
L
L
R
C
L
A
G
F
E
Q
P
D
S
G
E
I
S
L
S
G
-------------
K
T
I
-
F
S
K
N
T
N
----------
L
P
V
R
E
-
R
R
L
G
Y
L
V
Q
E
G
V
L
F
P
H
L
T
V
Y
R
N
I
A
Y
G
L
G
N
G
K
G
-
R
T
A
Q
E
R
Q
R
I
-
E
A
M
L
E
L
T
G
I
S
E
LAG
R
Y
--------
P
H
E
---
L
S
G
G
Q
Q
Q
R
A
A
L
A
R
A
L
A
P
-
D
P
E
L
I
L
L
D
E
P
F
S
A
L
D
E
Q
L
R
R
Q
I
R
E
D
M
I
A
A
L
R
A
-
N
-
G
K
S
A
V
F
V
S
H
D
R
E
E
A
L
Q
Y
A
D
R
I
A
V
M
K
Q
-
G
R
I
L
Q
T
A
S
P
H
E
L
Y
R
Q
P
A
D
------------------
45
PsiBlast_CBE
54.19
40%
50
- C1 -
-
3TIF
4
Y796_METJA
B:
[1-228]
----
M
V
K
L
K
N
V
T
K
T
Y
K
M
G
E
EIIY
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
--
Y
I
-------------
D
N
I
-
K
T
N
D
L
D
DDE-------
L
T
K
I
R
R
D
K
I
G
F
V
F
Q
Q
F
N
L
I
P
L
L
T
A
L
E
N
--
V
E
L
P
L
I
F
K
Y
R
G
A
M
S
G
E
E
R
R
K
R
A
L
E
C
L
K
M
A
E
LEE
R
F
--
A
N
H
K
--
P
N
Q
---
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
-
N
P
P
I
I
L
A
D
Q
P
T
W
A
L
D
S
K
T
G
E
K
I
M
Q
-
L
L
K
K
L
N
E
-
E
D
G
K
T
V
V
V
V
T
H
D
I
N
V
A
R
-
F
G
E
R
I
I
Y
L
K
D
-
G
E
V
E
R
E
E
K
----------------------------
94
PsiBlast_CBE
53.16
35%
-36
- C1 -
-
2FGK
2
D:
[24-235]
-----------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
-------------
H
D
L
-
A
L
A
--
D
----------
P
N
W
L
R
-
R
Q
V
G
V
V
L
Q
D
-
N
V
L
L
N
R
S
I
I
D
N
I
S
L
A
N
P
G
M
S
V
-
E
K
V
I
Y
A
A
K
L
A
G
A
H
D
F
I
S
E
L
R
E
---
G
Y
--
N
T
I
V
--
G
E
Q
GAG
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
-
N
P
K
I
L
I
F
D
Q
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
-
N
M
H
K
I
C
K
---
G
R
T
V
I
I
I
A
H
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
-
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
-------------------
95
PsiBlast_CBE
52.75
35%
-32
- C1 -
-
2FGK
2
HLYBP_ECOLX
C:
[24-235]
-----------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
-------------
H
D
L
-
A
L
A
--
D
----------
P
N
W
L
R
-
R
Q
V
G
V
V
L
Q
D
-
N
V
L
L
N
R
S
I
I
D
N
I
S
L
A
N
P
G
M
S
V
-
E
K
V
I
Y
A
A
K
L
A
G
A
H
D
F
I
S
E
L
R
E
---
G
Y
--
N
T
I
V
--
G
E
Q
GAG
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
-
N
P
K
I
L
I
F
D
Q
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
-
N
M
H
K
I
C
K
---
G
R
T
V
I
I
I
A
H
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
-
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
-------------------
96
PsiBlast_CBE
52.64
35%
-34
- C1 -
-
2FGK
2
HLYBP_ECOLX
B:
[24-235]
-----------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
-------------
H
D
L
-
A
L
A
--
D
----------
P
N
W
L
R
-
R
Q
V
G
V
V
L
Q
D
-
N
V
L
L
N
R
S
I
I
D
N
I
S
L
A
N
P
G
M
S
V
-
E
K
V
I
Y
A
A
K
L
A
G
A
H
D
F
I
S
E
L
R
E
---
G
Y
--
N
T
I
V
--
G
E
Q
GAG
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
-
N
P
K
I
L
I
F
D
Q
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
-
N
M
H
K
I
C
K
---
G
R
T
V
I
I
I
A
H
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
-
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
-------------------
97
PsiBlast_CBE
52.19
35%
-34
- C1 -
-
2FGK
2
HLYBP_ECOLX
A:
[24-235]
-----------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
-------------
H
D
L
-
A
L
A
--
D
----------
P
N
W
L
R
-
R
Q
V
G
V
V
L
Q
D
-
N
V
L
L
N
R
S
I
I
D
N
I
S
L
A
N
P
G
M
S
V
-
E
K
V
I
Y
A
A
K
L
A
G
A
H
D
F
I
S
E
L
R
E
---
G
Y
--
N
T
I
V
--
G
E
Q
GAG
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
-
N
P
K
I
L
I
F
D
Q
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
-
N
M
H
K
I
C
K
---
G
R
T
V
I
I
I
A
H
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
-
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
-------------------
89
PsiBlast_CBE
51.44
35%
-33
- C1 -
-
2FF7
1
A:
[24-235]
-----------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
-------------
H
D
L
-
A
L
A
--
D
----------
P
N
W
L
R
-
R
Q
V
G
V
V
L
Q
D
-
N
V
L
L
N
R
S
I
I
D
N
I
S
L
A
N
P
G
M
S
V
-
E
K
V
I
Y
A
A
K
L
A
G
A
H
D
F
I
S
E
L
R
E
---
G
Y
--
N
T
I
V
--
G
E
Q
GAG
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
-
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
-
N
M
H
K
I
C
K
---
G
R
T
V
I
I
I
A
H
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
-
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
-------------------
107
PsiBlast_CBE
51.09
35%
-25
- C1 -
-
2FFA
2
A:
[24-235]
-----------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
-------------
H
D
L
-
A
L
A
--
D
----------
P
N
W
L
R
-
R
Q
V
G
V
V
L
Q
D
-
N
V
L
L
N
R
S
I
I
D
N
I
S
L
A
N
P
G
M
S
V
-
E
K
V
I
Y
A
A
K
L
A
G
A
H
D
F
I
S
E
L
R
E
---
G
Y
--
N
T
I
V
--
G
E
Q
GAG
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
-
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
-
N
M
H
K
I
C
K
---
G
R
T
V
I
I
I
A
A
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
-
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
-------------------
111
PsiBlast_CBE
51.00
35%
-33
- C1 -
-
1XEF
2
HLYBP_ECOLX
A:
[18-229]
-----------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
-------------
H
D
L
-
A
L
A
--
D
----------
P
N
W
L
R
-
R
Q
V
G
V
V
L
Q
D
-
N
V
L
L
N
R
S
I
I
D
N
I
S
L
A
N
P
G
M
S
V
-
E
K
V
I
Y
A
A
K
L
A
G
A
H
D
F
I
S
E
L
R
E
---
G
Y
--
N
T
I
V
--
G
E
Q
GAG
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
-
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
-
N
M
H
K
I
C
K
---
G
R
T
V
I
I
I
A
A
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
-
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
-------------------
103
PsiBlast_CBE
50.70
35%
-29
- C1 -
-
2FGJ
2
D:
[24-235]
-----------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
-------------
H
D
L
-
A
L
A
--
D
----------
P
N
W
L
R
-
R
Q
V
G
V
V
L
Q
D
-
N
V
L
L
N
R
S
I
I
D
N
I
S
L
A
N
P
G
M
S
V
-
E
K
V
I
Y
A
A
K
L
A
G
A
H
D
F
I
S
E
L
R
E
---
G
Y
--
N
T
I
V
--
G
E
Q
GAG
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
-
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
-
N
M
H
K
I
C
K
---
G
R
T
V
I
I
I
A
A
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
-
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
-------------------