@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : spr0437: (2017-12-22 )
MRRNALELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQNYLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDDEVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAYDAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE
Atome Classification :
(20 SA)
-----------------------------------------------------------------------------------------------------------------------------------------------------.........10.---.......--20.....-.-..30.....--...40---------........50--.-------.......60........70-...------.....80-------..-------------.......90........100....------...110.----------......120...------....130.......140.....---....150.......-------------------------------160.......170.......180.......-190.......200------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
-----------------------------------------------------------------------------------------------------------------------------------------------------MRRN
A
L
E
L
E
V
FA---GQ
E
K
S
E
L
--
S
M
I
E
V
A
R
-
A
-
I
L
E
LRGRDH--EM
H
F
S
---------
D
L
V
N
E
I
Q
N
YL--G-------TSN
S
D
I
R
E
A
L
P
L
F
Y
T
E
LNF-DG
S
------
F
I
S
LGD--------NK-------------WGLRSWY
G
V
D
E
I
D
E
E
I
I
A
LEENDD------DEVA
P
K
A
----------
K
K
K
R
V
N
A
F
MDGD------SDAIDYNADDPEDED--AYEAD---PALSYDDENPDDEK-------------------------------NE
V
E
A
YDA
E
I
N
EIAPDDLGEDVDLNEDDDE-FSDDDAETSEE--------------------------------------------
4
PsiBlast_PDB
71.44
37%
-177
- C4 -
-
4NC8
-
RPOE_BACSU
A:
[5-81]
---------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
S
---
Q
E
E
L
K
E
M
--
A
L
V
E
I
A
H
-
E
-
L
F
E
E
H
K
K
P
----
V
P
F
Q
---------
E
L
L
N
E
I
A
S
L
L
--
G
-------
V
K
K
E
E
L
G
D
R
I
A
Q
F
Y
T
D
L
N
I
-
D
G
R
------
F
L
A
L
S
D
--------
Q
T
-------------
W
G
L
R
S
W
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
HHSearch
71.00
36%
-165
- C4 -
-
2M4K
-
RPOE_BACSU
A:
[2-82]
-----------------------------------------------------------------------------------------------------------------------------------------------------------
G
I
K
Q
Y
S
---
Q
E
E
L
K
E
M
--
A
L
V
E
I
A
H
-
E
-
L
F
E
E
H
K
K
----
P
V
P
F
Q
---------
E
L
L
N
E
I
A
S
L
L
--
G
-------
V
K
K
E
E
L
G
D
R
I
A
Q
F
Y
T
D
L
N
I
-
D
G
R
------
F
L
A
L
S
D
--------
Q
T
-------------
W
G
L
R
S
W
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
70.84
37%
-170
- C4 -
-
2M4K
-
RPOE_BACSU
A:
[6-82]
---------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
S
---
Q
E
E
L
K
E
M
--
A
L
V
E
I
A
H
-
E
-
L
F
E
E
H
K
K
P
----
V
P
F
Q
---------
E
L
L
N
E
I
A
S
L
L
--
G
-------
V
K
K
E
E
L
G
D
R
I
A
Q
F
Y
T
D
L
N
I
-
D
G
R
------
F
L
A
L
S
D
--------
Q
T
-------------
W
G
L
R
S
W
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
69.53
37%
-166
- C4 -
-
4NC7
1
RPOE_BACSU
A:
[5-81]
---------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
S
---
Q
E
E
L
K
E
M
--
A
L
V
E
I
A
H
-
E
-
L
F
E
E
H
K
K
P
----
V
P
F
Q
---------
E
L
L
N
E
I
A
S
L
L
--
G
-------
V
K
K
E
E
L
G
D
R
I
A
Q
F
Y
T
D
L
N
I
-
D
G
R
------
F
L
A
L
S
D
--------
Q
T
-------------
W
G
L
R
S
W
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
HHSearch
69.47
36%
-160
- C4 -
-
4NC7
-
RPOE_BACSU
B:
[3-81]
-------------------------------------------------------------------------------------------------------------------------------------------------------------
K
Q
Y
S
---
Q
E
E
L
K
E
M
--
A
L
V
E
I
A
H
-
E
-
L
F
E
E
H
K
K
----
P
V
P
F
Q
---------
E
L
L
N
E
I
A
S
L
L
--
G
-------
V
K
K
E
E
L
G
D
R
I
A
Q
F
Y
T
D
L
N
I
-
D
G
R
------
F
L
A
L
S
D
--------
Q
T
-------------
W
G
L
R
S
W
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
69.06
37%
-122
- C4 -
-
2KRC
-
RPOE_BACSU
A:
[6-90]
---------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
S
---
Q
E
E
L
K
E
M
--
A
L
V
E
I
A
H
-
E
-
L
F
E
E
H
K
K
P
----
V
P
F
Q
---------
E
L
L
N
E
I
A
S
L
L
--
G
-------
V
K
K
E
E
L
G
D
R
I
A
Q
F
Y
T
D
L
N
I
-
D
G
R
------
F
L
A
L
S
D
--------
Q
T
-------------
W
G
L
R
S
W
Y
P
Y
D
Q
L
D
E
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38
Fugue
65.83
33%
-73
- C4 -
-
2KRC
-
RPOE_BACSU
A:
[2-100]
-----------------------------------------------------------------------------------------------------------------------------------------------------------
G
I
K
Q
Y
S
---
Q
E
E
L
K
E
M
--
A
L
V
E
I
A
H
-
E
-
L
F
E
E
H
K
K
----
P
V
P
F
Q
---------
E
L
L
N
E
I
A
S
L
L
--
G
-------
V
K
K
E
E
L
G
D
R
I
A
Q
F
Y
T
D
L
N
I
-
D
G
R
------
F
L
A
L
S
D
--------
Q
T
-------------
W
G
L
R
S
W
Y
P
Y
D
Q
L
D
E
E
T
Q
L
E
H
H
H
H
H
------
H
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
42
Fugue
64.71
20%
35
- C2 -
-
5J1S
2
TOR1A_HUMAN
A:
[7-283]
----------------------------------------------------------------------------------------------------------------------------------------------------S
L
S
R
E
A
L
Q
K
D
L
D
D
NLF
G
Q
H
L
A
K
K
--
I
I
L
N
A
V
F
-
G
-
F
I
N
N
P
K
P
K
K
--
P
L
T
L
S
L
H
G
W
T
GTG
K
N
F
V
S
K
I
I
A
E
N
--
I
-------
Y
E
G
G
L
N
S
D
Y
V
H
L
F
V
A
T
L
H
F
P
H
A
S
------
N
I
T
L
Y
K
--------
D
Q
-------------
L
Q
L
W
I
R
G
N
V
S
A
C
A
R
S
I
F
I
F
D
Q
M
D
K
MH
A
G
L
I
D
A
I
K
P
F
L
DYYDLVDGVS
Y
Q
K
A
M
F
I
F
L
S
N
A
G
A
E
R
I
T
D
V
A
L
D
F
W
R
S
G
K
Q
R
E
D
IK
L
K
D
I
E
---
H
A
L
S
V
S
V
F
N
N
K
N
S
G
F
W
HSSLIDRNLID
Y
F
V
P
F
L
P
LE
Y
K
H
L
K
M
C
I
R
V
E
M
Q
S
R
G
Y
E
I
D
E
D
I
V
S
R
V
A
E
E
M
T
F
F
P
K
E
E
R
V
F
S
D
K
G
C
K
T
V
F
T
K
L
D
Y
Y
Y
D-------------------------------------
36
HHSearch
49.77
16%
-135
- C4 -
-
1VTN
2
C:
[7-82]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
Y
I
S
L
I
T
-
M
A
I
Q
Q
A
P
G
K
----
M
L
T
L
S
---------
E
I
Y
Q
W
I
M
D
L
F
--
P
-------
Y
Y
R
E
N
Q
Q
R
W
Q
N
S
I
R
H
S
L
S
F
-
N
D
C
------
F
V
K
V
A
R
SPDKPGKG
S
Y
-------------
W
A
L
H
P
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
HHSearch
49.28
13%
-218
- C4 -
-
5SXY
-
?
A:
[36-87]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
T
F
--
D
L
D
D
N
A
V
-
A
-
V
L
K
L
V
D
G
----
R
N
T
V
S
---------
Q
I
A
Q
I
L
G
Q
T
Y
--
D
-------
A
D
P
A
I
I
E
A
D
I
L
P
M
L
A
G
L
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
48.82
9%
-228
- C4 -
-
3G2B
-
PQQD_XANCP
A:
[37-89]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
V
V
--
E
L
D
D
I
A
L
-
V
-
V
A
Q
R
Y
D
G
----
T
Q
S
L
A
---------
Q
I
A
Q
T
L
A
A
E
F
--
D
-------
A
D
A
S
E
I
E
T
D
V
I
E
L
T
T
T
L
H
Q
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
41
Fugue
47.81
15%
57
* C3 *
-
5JI7
-
RANB9_HUMAN
A:
[40-238]
-----------------------------------------------------------------------------------------------------------------------------------------------------
L
Q
R
R
L
K
R
L
Y
P
A
V
---
D
E
Q
E
T
P
L
PR
S
W
S
P
K
D
K
F
S
-
Y
I
G
L
S
Q
N
N
L
--
R
V
H
Y
K
G--------
H
G
K
T
P
K
D
A
A
S
--
V
-------
R
A
T
H
P
I
P
A
A
C
G
I
Y
Y
F
E
V
K
I
-
V
S
K
GRDGY
M
G
I
G
L
S
A
--------
Q
G
-------------
V
N
M
N
R
L
P
G
---
W
D
K
H
S
Y
G
Y
H
G
D
D
G
------
H
S
F
C
S
S
G
----------
T
G
Q
P
Y
G
P
T
F
T
-
T
------
G
D
V
I
G
C
C
V
N
L
I
N
N
T
C
--
F
Y
T
K
N
G
H
S
L
G
I
A
F
T
D
L
P
P
N
------------------------------------------
L
Y
P
T
V
G
L
Q
T
P
G
E
V
V
D
A
N
F
G
Q
H
P
-
F
V
F
D
I
E
D
Y
M
R
E
W-------------------------------------------
22
HHSearch
46.34
22%
-43
- C4 -
-
2OD5
6
?
A:
[15-88]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
I
R
E
K
I
K
-
K
-
F
L
G
D
R
------
P
R
N
T
A
---------
E
I
L
E
H
I
N
S
T
M
R
H
G
-------
T
T
-------
S
Q
Q
L
G
N
V
L
S
K
-
D
K
D
------
I
V
K
V
G
Y
--------
I
K
R
S
G
ILSG
G
Y
D
I
C
E
W
A
T
R
N
W
V
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
45.00
25%
-20
- C4 -
-
4FM9
1
A:
[296-396]
------------------------------------------------------------------------------------------------------------------------------------------------------
Q
R
K
V
L
-
F
T
C
F
K
---
R
N
D
K
R
E
V
--
K
V
A
Q
L
A
G
-
S
-
V
A
E
M
S
S
Y
H
H
G-
E
M
S
L
M
M
--------
T
I
I
N
L
A
Q
N
F
V
--
G
-------
S
N
N
L
N
L
L
Q
P
I
G
Q
F
G
T
R
L
H
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
Fugue
43.18
16%
101
- C1 -
-
4OV4
1
?
A:
[23-408]
P
K
T
I
H
I
Q
D
VTLR
D
G
N
Q
A
LK
R
P
W
T
I
D
E
K
I
E
V
F
D
L
L
V
E
L
NVDGIEVGFPSSN
E
T
E
F
H
T
C
Q
V
L
S
K
R
APKG
K
P
I
A
A
L
S
R
AN
Q
N
E
I
A
V
T
W
E
A
IQKAD
C
P
R
M
H
I
V
Y
P
V
S
D
F
S
I
K
HVLKIS
E
K
E
V
L
Q
K
I
R
N
S
I
S
F
A
R
S
I
V
GPG
I
E
I
Q
F
S
GEHFGDA
I
E
N
F
A
F
T
K
E
A
F
L
---
T
A
I
E
A
G
A
--
N
I
I
N
L
P
N
-
T
-
V
----
E
R
Y
R
--
P
M
V
F
V
---------
N
M
V
K
E
I
K
D
V
V
--
K
DK
A
I
I
S
I
H
T
H
N
D
L
G
M
A
T
A
T
S
V
E
S
V
Y
V
-
G
A
E
------
Q
I
E
V
A
L
--------
N
G
-------------
L
G
E
R
A
--
G
N
T
N
L
Y
E
T
A
I
A
L
H
Q
N
G
E
------
N
---
L
N
I
----------
N
F
Q
R
I
Y
P
T
A
K
R
I
------
S
E
L
T
G
I
P
I
G
E
K
----------
T
---
P
I
I
G
E
D
I
F
S
H
R
S
G
I
-------------------------------
H
Q
-
H
Q
S
K
G
A
Y
R
T
F
S
P
E
F
V
G
R
---
M
D
K
E
T
I
S
-
F
T
N
Q
S
G
H
K
A
I
E
F
L
L
H
Q
R
G
I
Q
V
S
K
E
G
I
H
H
L
F
S
L
A
K
S
I
S
S
R
ENNREIT
E
A
E
L
V
A
L
S
Q
9
PsiBlast_PDB
42.53
23%
0
- C4 -
-
4J3N
2
TOP2B_HUMAN
A:
[324-416]
------------------------------------------------------------------------------------------------------------------------------------------------------
Q
R
K
V
L
-
F
T
C
F
K
---
R
N
D
K
R
E
V
--
K
V
A
Q
L
A
G
-
S
-
V
A
E
M
S
A
Y
H
H
G
E
Q
A
L
M
M
---------
T
I
V
N
L
A
Q
N
F
V
--
G
-------
S
N
N
I
N
L
L
Q
P
I
G
Q
F
G
T
R
L
H
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
42.33
23%
-2
- C4 -
-
4G0V
2
TOP2B_HUMAN
A:
[324-416]
------------------------------------------------------------------------------------------------------------------------------------------------------
Q
R
K
V
L
-
F
T
C
F
K
---
R
N
D
K
R
E
V
--
K
V
A
Q
L
A
G
-
S
-
V
A
E
M
S
A
Y
H
H
G
E
Q
A
L
M
M
---------
T
I
V
N
L
A
Q
N
F
V
--
G
-------
S
N
N
I
N
L
L
Q
P
I
G
Q
F
G
T
R
L
H
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
42.26
23%
-8
- C4 -
-
3QX3
3
TOP2B_HUMAN
A:
[324-416]
------------------------------------------------------------------------------------------------------------------------------------------------------
Q
R
K
V
L
-
F
T
C
F
K
---
R
N
D
K
R
E
V
--
K
V
A
Q
L
A
G
-
S
-
V
A
E
M
S
A
Y
H
H
G
E
Q
A
L
M
M
---------
T
I
V
N
L
A
Q
N
F
V
--
G
-------
S
N
N
I
N
L
L
Q
P
I
G
Q
F
G
T
R
L
H
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
42.18
23%
-4
- C4 -
-
4G0W
2
TOP2B_HUMAN
A:
[324-416]
------------------------------------------------------------------------------------------------------------------------------------------------------
Q
R
K
V
L
-
F
T
C
F
K
---
R
N
D
K
R
E
V
--
K
V
A
Q
L
A
G
-
S
-
V
A
E
M
S
A
Y
H
H
G
E
Q
A
L
M
M
---------
T
I
V
N
L
A
Q
N
F
V
--
G
-------
S
N
N
I
N
L
L
Q
P
I
G
Q
F
G
T
R
L
H
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
HHSearch
41.86
12%
-155
- C4 -
-
1D5V
-
A:
[7-65]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
--
S
Y
I
A
L
I
T
M
A
-
I
Q
N
A
P
E
K
----
K
I
T
L
N
---------
G
I
Y
Q
F
I
M
D
R
F
--
P
-------
F
Y
R
E
N
K
Q
G
W
Q
N
S
I
R
H
N
L
S
L
-
N
E
C
------
F
V
K
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------