@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : spr0440: (2017-12-22 )
MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPENSGANTELVSGESEHSTNEADKQNEGEHARENKLEKAEGVATASETASPASNEAATTETAEAASAAKPEEKASEVVAETPSAEAKPKSDKETEAKPEATNQGDESKPAAEANKTEKEVQPDVPKNTEKTLKPKEIKFNSWEELLKWEPGAREDDAINRGSVVLASRRTGHLVNEKASKEAKVQALSNTNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDAGHRNGVPVYGTLFFNWSNSIADQERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFINQETTGDLVKPLGEKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYNYQFMQPEGDKVPADNFFANFNWDKAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKTKVKWNDILDENGKLRLSLGLFAPDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGDKDWYGIANLVADRTPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWRWWQTSTGEKLRAEYDFTDAYNGGNSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVAHKGGKGSKVYMAFSTTPDYKFDDADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFFEHEGAVKDYQFNLGQLTISDNHQEPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADFYEVYEKDGDSWKLLTGSSSTTIYLPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTTFDWGMTVKDTSLPKPLAENIVPGATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSAQLSGSVDIRLTKSRTVVRWVMDHAGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEVRGNKAHVTDITLDKPITAQDWRLNVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMAKAAARSLGNNKVQVGFADVPAGATITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQSGLLYYRTQLPGKEISNVLAVSVPKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLRVQYEGGTEDELIRLTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEASPKTILGIEVSQEPKKDYLVGDSLDLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQKTGRQTLTLRYQGHEVNFDVLVSPKAALNDEYLKQKLAEVEAAKNKVVYNFASPEVKEAFLKAIEAAEQVLKDHETSTQDQVNDRLNKLTEAHKALNGQEKFTEEKTELDRLTGEAQELLAAKPNHPSGSALAPLLEKNKALVEKVDLSPEELATAKQSLKDLVALLKEDKSAVFSDSKTGVEVHFSNKEKTVIKGLKVERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVDLSYASIVKIPIEKDKKVKKVFFLPEGKGAVELAFEQTDSHVIFTAPHFTHYAFVYESAEKPQPAKPAPQNKVLPKPTYQPASDQQKAPKLEVQEEKVAFHRQEHENTEMLVGEQRVIIQGRDGLLRHVFEVDEKGQRRLRSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQNTAVKSEEASKQLPNTGTADANEALIAGLASLGLASLALTLRRKREDKD
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260..-----..------.-.--.270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690........700.......710.......720.......730.......740.......750......-.760.......770.......780.......790.......800.......810.......820.......830.......840.....----..850.....--..860.......870.......880...-----....890.......----------900.......910....--------..--.920.....-...930.......940...--....950.......960.......970.......980.......990.......1000......1010......1020......1030......1040......1050......1060......1070......1080......1090......1100......1110......1120......1130......1140......1150......1160......1170......1180......1190......1200......1210......1220......1230......1240......1250......1260......1270......1280......1290......1300......1310......1320......1330......1340......1350......1360......1370......1380......1390......1400......1410......1420......1430......1440......1450......1460......1470......1480......1490......1500......1510......1520......1530......1540......1550......1560......1570......1580......1590......1600......1610......1620......1630......1640......1650......
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MKN
P
F
F
E
R
R
C
R
Y
S
I
R
KLS
V
G
A
C
S
L
M
I
G
A
V
L
FAGPALAEETAVPENSGANTELVSGESEHSTNEADKQNEG
E
H
A
R
E
N
K
L
E
K
AEGVATASETASPASNEAATT
E
T
AEAASAAK
P
E
E
K
A
S
E
V
V
AETPSAEAKPKSDKETEAKPEATNQGDESKPAAEANKTEKEVQPDVPKNTEKTLKPKEIKFN
S
W
E
E
L
LKWEPGAREDDAINRG
S
V
V
L
A
SRRTGHLVNEKASK
E
A
K
V
Q
A
LSNTNSKAK
D
H
ASV
G
G
E
E
F
K
A
Y
A
F
D
Y
W
Q
Y
L
D
S
M
V
F
W
-----EG------L-V--PT
P
D
V
IDAGHRNGV
P
V
Y
G
T
L
F
F
NWSNSI
A
D
Q
E
R
F
A
E
A
L
K
QDADGS
F
P
I
A
R
K
L
V
D
M
A
K
Y
YGYD
G
Y
F
INQETT
G
D
L
V
K
P
L
G
E
K
M
R
Q
F
M
L
Y
S
K
E
Y
A
A
KVNH
P
I
K
Y
S
W
Y
D
AMTYNYGRYHQDGLGEY
N
Y
Q
F
MQPEGDKVPAD
N
F
F
ANFNWDKAKN
D
Y
T
I
A
TANWIGR
N
P
Y
D
V
FA
G
L
E
LQQGGS
Y
K
T
K
V
K
W
N
D
ILDENG
K
L
R
L
S
LGLFAP
D
T
I
T
S
LGKTGEDYHKNE
D
I
F
F
TGYQGDPTGQKPGD
K
D
W
Y
G
I
A
N
L
VADRTPAVG
N
T
F
T
T
SFNTGHG
K
K
W
F
VDGKVSKDSEWNYRSVSGVLPT
W
R
W
WQTSTGE
K
L
R
A
EYDFTDAYNGGN
S
L
K
FSGDVAGKTDQ
D
V
R
L
Y
S
T
K
L
E
V
T
E
K
T
K
L
R
V
A
HKGGKG
S
K
V
Y
M
A
F
STTPDYKFDD
A
D
A
W
K
E
L
TLSDNWTNEEF
D
L
S
S
LAG
K
T
I
Y
A
V
K
L
F
F
EHEGAVK
D
Y
-
Q
F
NL
G
Q
L
T
ISDNHQEPQSPT
S
F
S
V
V
K
Q
S
L
K
N
A
Q
E
A
E
A
V
V
Q
FKGNKD
A
D
F
Y
E
V
Y
EKDGD
S
W
K
L
L
TGSS-
S
T
T
I
Y
L
PKVSRSASAQGT
T
Q
E
L
K
V
V
A
VGKNGVRSEAA
T
T
T
F
DWG
M
T
VKDTSLP
K
P
L
A
E
NIVPG
A
T
VIDSTFPKTEGGEG
I
E
G
M
LNGT
I
T
----
S
LSDKWSSAQ--LSG
S
V
D
I
R
L
TKS
R
T
V
V
R
W
V
M
D
HAGAGGE-----SVNDGLMNTK
D
F
D
L
----------
Y
Y
KDADG
E
W
K
L
A
K
E
VRG--------NK--
A
H
-
V
T
D
I
TL-DKPITAQ
D
W
R
L
N
V
V
TSDNG--T
P
W
K
A
I
R
I
YN
W
K
M
Y
E
KLDTESVNI
P
M
A
K
A
A
A
R
SLGNN
K
V
Q
V
G
F
ADVPAG
A
T
I
T
V
YDNPNSQT
P
L
A
T
L
K
S
E
VGGDLASAPLDLTNQS
G
L
L
Y
Y
R
TQL
P
G
K
E
I
S
N
V
L
A
V
SVPKDD
R
R
I
K
S
V
SLETGPKKTSYAEGEDLDLRG
G
V
L
R
V
Q
YEGGTED
E
L
I
R
L
T
HAG
V
S
VSGFDTHHKGEQN
L
T
L
Q
YLGQPVNA
N
L
S
V
T
V
TGQDEASP
K
T
I
L
G
I
EVSQEPKKDYLVGDSLDLSEG
R
F
A
V
A
YSNDTMEEHSFTDEG
V
E
ISGYDAQKTG
R
Q
T
L
T
L
R
Y
QG
H
E
V
N
F
D
V
L
VS
P
K
A
AL
N
D
E
Y
L
K
Q
K
L
A
E
V
E
AAKN
K
V
V
Y
NFAS
P
E
V
K
E
A
F
L
K
A
I
E
A
A
E
Q
V
L
K
DHETS
T
Q
D
Q
V
N
D
R
L
N
K
L
T
E
A
H
K
ALN
G
Q
E
K
F
T
E
E
K
T
E
L
D
R
L
T
G
E
A
Q
E
L
L
AAKPNHPSG
S
A
L
A
P
L
L
E
K
N
K
A
L
V
E
KVDL
S
P
E
E
L
A
T
A
K
Q
S
L
K
D
L
V
A
L
L
K
ED
K
S
A
VFSDSKT
G
V
E
V
H
FSNK
E
K
T
V
I
KG
L
K
V
E
R
V
QAS
A
E
EKKYFAGED
A
H
V
F
E
I
EGLDEKGQDVD
L
S
Y
A
S
I
V
K
IPIEKDK
K
V
K
K
V
F
F
LPEGK
G
A
V
E
L
A
F
EQTDS
H
V
I
F
TAPHF
T
H
Y
A
F
V
YESAEKPQPAKPAPQNKVLPKPTYQPASDQQKAPKL
E
V
Q
E
E
K
V
A
F
H
R
Q
EHENT
E
M
L
VGE
Q
R
V
I
I
QGR
D
G
L
L
R
H
V
F
EV
D
E
K
G
Q
R
RL
R
S
T
E
V
I
Q
E
A
I
P
E
I
V
E
IGTKV
K
T
V
P
A
V
V
ATQEKPAQNTAVK
S
E
E
A
S
K
QLPNTGTAD
A
N
E
A
L
I
A
G
L
A
S
L
G
L
A
S
L
A
L
T
L
R
R
KREDKD
34
Fugue
90.54
100%
-27
- C4 -
-
2W91
1
?
A:
[6-640]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
L
K
P
K
E
I
K
F
N
S
W
E
E
L
L
K
W
E
P
G
A
R
E
D
D
A
I
N
R
G
S
V
V
L
A
S
R
R
T
G
H
L
V
N
E
K
A
S
K
E
A
K
V
Q
A
L
S
N
T
N
S
K
A
K
D
H
A
S
V
G
G
E
E
F
K
A
Y
A
F
D
Y
W
Q
Y
L
D
S
M
V
F
W
-----
E
G
------
L
-
V
--
P
T
P
D
V
I
D
A
G
H
R
N
G
V
P
V
Y
G
T
L
F
F
N
W
S
N
S
I
A
D
Q
E
R
F
A
E
A
L
K
Q
D
A
D
G
S
F
P
I
A
R
K
L
V
D
M
A
K
Y
Y
G
Y
D
G
Y
F
I
N
Q
E
T
T
G
D
L
V
K
P
L
G
E
K
M
R
Q
F
M
L
Y
S
K
E
Y
A
A
K
V
N
H
P
I
K
Y
S
W
Y
D
A
M
T
Y
N
Y
G
R
Y
H
Q
D
G
L
G
E
Y
N
Y
Q
F
M
Q
P
E
G
D
K
V
P
A
D
N
F
F
A
N
F
N
W
D
K
A
K
N
D
Y
T
I
A
T
A
N
W
I
G
R
N
P
Y
D
V
F
A
G
L
E
L
Q
Q
G
G
S
Y
K
T
K
V
K
W
N
D
I
L
D
E
N
G
K
L
R
L
S
L
G
L
F
A
P
D
T
I
T
S
L
G
K
T
G
E
D
Y
H
K
N
E
D
I
F
F
T
G
Y
Q
G
D
P
T
G
Q
K
P
G
D
K
D
W
Y
G
I
A
N
L
V
A
D
R
T
P
A
V
G
N
T
F
T
T
S
F
N
T
G
H
G
K
K
W
F
V
D
G
K
V
S
K
D
S
E
W
N
Y
R
S
V
S
G
V
L
P
T
W
R
W
W
Q
T
S
T
G
E
K
L
R
A
E
Y
D
F
T
D
A
Y
N
G
G
N
S
L
K
F
S
G
D
V
A
G
K
T
D
Q
D
V
R
L
Y
S
T
K
L
E
V
T
E
K
T
K
L
R
V
A
H
K
G
G
K
G
S
K
V
Y
M
A
F
S
T
T
P
D
Y
K
F
D
D
A
D
A
W
K
E
L
T
L
S
D
N
W
T
N
E
E
F
D
L
S
S
L
A
G
K
T
I
Y
A
V
K
L
F
F
E
H
E
G
A
V
K
D
Y
-
Q
F
N
L
G
Q
L
T
I
S
D
N
H
Q
E
P
Q
S
P
T
S
F
S
V
V
K
Q
S
L
K
N
A
Q
E
A
E
A
V
V
Q
F
K
G
N
K
D
A
D
F
Y
E
V
Y
E
K
D
G
D
S
W
K
L
L
T
G
S
S
-
S
T
T
I
Y
L
P
K
V
S
R
S
A
S
A
Q
G
T
T
Q
E
L
K
V
V
A
V
G
K
N
G
V
R
S
E
A
A
T
T
T
F
D
W
G
M
T
V
K
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
90.54
100%
-27
- C4 -
-
2W91
1
?
A:
[6-640]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
L
K
P
K
E
I
K
F
N
S
W
E
E
L
L
K
W
E
P
G
A
R
E
D
D
A
I
N
R
G
S
V
V
L
A
S
R
R
T
G
H
L
V
N
E
K
A
S
K
E
A
K
V
Q
A
L
S
N
T
N
S
K
A
K
D
H
A
S
V
G
G
E
E
F
K
A
Y
A
F
D
Y
W
Q
Y
L
D
S
M
V
F
W
-----
E
G
------
L
-
V
--
P
T
P
D
V
I
D
A
G
H
R
N
G
V
P
V
Y
G
T
L
F
F
N
W
S
N
S
I
A
D
Q
E
R
F
A
E
A
L
K
Q
D
A
D
G
S
F
P
I
A
R
K
L
V
D
M
A
K
Y
Y
G
Y
D
G
Y
F
I
N
Q
E
T
T
G
D
L
V
K
P
L
G
E
K
M
R
Q
F
M
L
Y
S
K
E
Y
A
A
K
V
N
H
P
I
K
Y
S
W
Y
D
A
M
T
Y
N
Y
G
R
Y
H
Q
D
G
L
G
E
Y
N
Y
Q
F
M
Q
P
E
G
D
K
V
P
A
D
N
F
F
A
N
F
N
W
D
K
A
K
N
D
Y
T
I
A
T
A
N
W
I
G
R
N
P
Y
D
V
F
A
G
L
E
L
Q
Q
G
G
S
Y
K
T
K
V
K
W
N
D
I
L
D
E
N
G
K
L
R
L
S
L
G
L
F
A
P
D
T
I
T
S
L
G
K
T
G
E
D
Y
H
K
N
E
D
I
F
F
T
G
Y
Q
G
D
P
T
G
Q
K
P
G
D
K
D
W
Y
G
I
A
N
L
V
A
D
R
T
P
A
V
G
N
T
F
T
T
S
F
N
T
G
H
G
K
K
W
F
V
D
G
K
V
S
K
D
S
E
W
N
Y
R
S
V
S
G
V
L
P
T
W
R
W
W
Q
T
S
T
G
E
K
L
R
A
E
Y
D
F
T
D
A
Y
N
G
G
N
S
L
K
F
S
G
D
V
A
G
K
T
D
Q
D
V
R
L
Y
S
T
K
L
E
V
T
E
K
T
K
L
R
V
A
H
K
G
G
K
G
S
K
V
Y
M
A
F
S
T
T
P
D
Y
K
F
D
D
A
D
A
W
K
E
L
T
L
S
D
N
W
T
N
E
E
F
D
L
S
S
L
A
G
K
T
I
Y
A
V
K
L
F
F
E
H
E
G
A
V
K
D
Y
-
Q
F
N
L
G
Q
L
T
I
S
D
N
H
Q
E
P
Q
S
P
T
S
F
S
V
V
K
Q
S
L
K
N
A
Q
E
A
E
A
V
V
Q
F
K
G
N
K
D
A
D
F
Y
E
V
Y
E
K
D
G
D
S
W
K
L
L
T
G
S
S
-
S
T
T
I
Y
L
P
K
V
S
R
S
A
S
A
Q
G
T
T
Q
E
L
K
V
V
A
V
G
K
N
G
V
R
S
E
A
A
T
T
T
F
D
W
G
M
T
V
K
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
90.54
100%
-27
- C4 -
-
2W91
1
?
A:
[6-640]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
L
K
P
K
E
I
K
F
N
S
W
E
E
L
L
K
W
E
P
G
A
R
E
D
D
A
I
N
R
G
S
V
V
L
A
S
R
R
T
G
H
L
V
N
E
K
A
S
K
E
A
K
V
Q
A
L
S
N
T
N
S
K
A
K
D
H
A
S
V
G
G
E
E
F
K
A
Y
A
F
D
Y
W
Q
Y
L
D
S
M
V
F
W
-----
E
G
------
L
-
V
--
P
T
P
D
V
I
D
A
G
H
R
N
G
V
P
V
Y
G
T
L
F
F
N
W
S
N
S
I
A
D
Q
E
R
F
A
E
A
L
K
Q
D
A
D
G
S
F
P
I
A
R
K
L
V
D
M
A
K
Y
Y
G
Y
D
G
Y
F
I
N
Q
E
T
T
G
D
L
V
K
P
L
G
E
K
M
R
Q
F
M
L
Y
S
K
E
Y
A
A
K
V
N
H
P
I
K
Y
S
W
Y
D
A
M
T
Y
N
Y
G
R
Y
H
Q
D
G
L
G
E
Y
N
Y
Q
F
M
Q
P
E
G
D
K
V
P
A
D
N
F
F
A
N
F
N
W
D
K
A
K
N
D
Y
T
I
A
T
A
N
W
I
G
R
N
P
Y
D
V
F
A
G
L
E
L
Q
Q
G
G
S
Y
K
T
K
V
K
W
N
D
I
L
D
E
N
G
K
L
R
L
S
L
G
L
F
A
P
D
T
I
T
S
L
G
K
T
G
E
D
Y
H
K
N
E
D
I
F
F
T
G
Y
Q
G
D
P
T
G
Q
K
P
G
D
K
D
W
Y
G
I
A
N
L
V
A
D
R
T
P
A
V
G
N
T
F
T
T
S
F
N
T
G
H
G
K
K
W
F
V
D
G
K
V
S
K
D
S
E
W
N
Y
R
S
V
S
G
V
L
P
T
W
R
W
W
Q
T
S
T
G
E
K
L
R
A
E
Y
D
F
T
D
A
Y
N
G
G
N
S
L
K
F
S
G
D
V
A
G
K
T
D
Q
D
V
R
L
Y
S
T
K
L
E
V
T
E
K
T
K
L
R
V
A
H
K
G
G
K
G
S
K
V
Y
M
A
F
S
T
T
P
D
Y
K
F
D
D
A
D
A
W
K
E
L
T
L
S
D
N
W
T
N
E
E
F
D
L
S
S
L
A
G
K
T
I
Y
A
V
K
L
F
F
E
H
E
G
A
V
K
D
Y
-
Q
F
N
L
G
Q
L
T
I
S
D
N
H
Q
E
P
Q
S
P
T
S
F
S
V
V
K
Q
S
L
K
N
A
Q
E
A
E
A
V
V
Q
F
K
G
N
K
D
A
D
F
Y
E
V
Y
E
K
D
G
D
S
W
K
L
L
T
G
S
S
-
S
T
T
I
Y
L
P
K
V
S
R
S
A
S
A
Q
G
T
T
Q
E
L
K
V
V
A
V
G
K
N
G
V
R
S
E
A
A
T
T
T
F
D
W
G
M
T
V
K
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
90.23
100%
-27
- C4 -
-
2W92
2
?
A:
[6-640]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
L
K
P
K
E
I
K
F
N
S
W
E
E
L
L
K
W
E
P
G
A
R
E
D
D
A
I
N
R
G
S
V
V
L
A
S
R
R
T
G
H
L
V
N
E
K
A
S
K
E
A
K
V
Q
A
L
S
N
T
N
S
K
A
K
D
H
A
S
V
G
G
E
E
F
K
A
Y
A
F
D
Y
W
Q
Y
L
D
S
M
V
F
W
-----
E
G
------
L
-
V
--
P
T
P
D
V
I
D
A
G
H
R
N
G
V
P
V
Y
G
T
L
F
F
N
W
S
N
S
I
A
D
Q
E
R
F
A
E
A
L
K
Q
D
A
D
G
S
F
P
I
A
R
K
L
V
D
M
A
K
Y
Y
G
Y
D
G
Y
F
I
N
Q
E
T
T
G
D
L
V
K
P
L
G
E
K
M
R
Q
F
M
L
Y
S
K
E
Y
A
A
K
V
N
H
P
I
K
Y
S
W
Y
D
A
M
T
Y
N
Y
G
R
Y
H
Q
D
G
L
G
E
Y
N
Y
Q
F
M
Q
P
E
G
D
K
V
P
A
D
N
F
F
A
N
F
N
W
D
K
A
K
N
D
Y
T
I
A
T
A
N
W
I
G
R
N
P
Y
D
V
F
A
G
L
E
L
Q
Q
G
G
S
Y
K
T
K
V
K
W
N
D
I
L
D
E
N
G
K
L
R
L
S
L
G
L
F
A
P
D
T
I
T
S
L
G
K
T
G
E
D
Y
H
K
N
E
D
I
F
F
T
G
Y
Q
G
D
P
T
G
Q
K
P
G
D
K
D
W
Y
G
I
A
N
L
V
A
D
R
T
P
A
V
G
N
T
F
T
T
S
F
N
T
G
H
G
K
K
W
F
V
D
G
K
V
S
K
D
S
E
W
N
Y
R
S
V
S
G
V
L
P
T
W
R
W
W
Q
T
S
T
G
E
K
L
R
A
E
Y
D
F
T
D
A
Y
N
G
G
N
S
L
K
F
S
G
D
V
A
G
K
T
D
Q
D
V
R
L
Y
S
T
K
L
E
V
T
E
K
T
K
L
R
V
A
H
K
G
G
K
G
S
K
V
Y
M
A
F
S
T
T
P
D
Y
K
F
D
D
A
D
A
W
K
E
L
T
L
S
D
N
W
T
N
E
E
F
D
L
S
S
L
A
G
K
T
I
Y
A
V
K
L
F
F
E
H
E
G
A
V
K
D
Y
-
Q
F
N
L
G
Q
L
T
I
S
D
N
H
Q
E
P
Q
S
P
T
S
F
S
V
V
K
Q
S
L
K
N
A
Q
E
A
E
A
V
V
Q
F
K
G
N
K
D
A
D
F
Y
E
V
Y
E
K
D
G
D
S
W
K
L
L
T
G
S
S
-
S
T
T
I
Y
L
P
K
V
S
R
S
A
S
A
Q
G
T
T
Q
E
L
K
V
V
A
V
G
K
N
G
V
R
S
E
A
A
T
T
T
F
D
W
G
M
T
V
K
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
89.80
99%
-29
- C4 -
-
3GDB
3
?
A:
[157-790]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
L
K
P
K
E
I
K
F
N
S
W
E
E
L
L
K
W
E
P
G
A
R
E
D
D
A
I
N
R
G
S
V
V
L
A
S
R
R
T
G
H
L
V
N
E
K
A
S
K
E
A
K
V
Q
A
L
S
N
T
N
S
K
A
K
D
H
A
S
V
G
G
E
E
F
K
A
Y
A
F
D
Y
W
Q
Y
L
D
S
M
V
F
W
-----
E
G
------
L
-
V
--
P
T
P
D
V
I
D
A
G
H
R
N
G
V
P
V
Y
G
T
L
F
F
N
W
S
N
S
I
A
D
Q
E
R
F
A
E
A
L
K
Q
D
A
D
G
S
F
P
I
A
R
K
L
V
D
M
A
K
Y
Y
G
Y
D
G
Y
F
I
N
Q
E
T
T
G
D
L
V
K
P
L
G
E
K
M
R
Q
F
M
L
Y
S
K
E
Y
A
A
K
V
N
H
P
I
K
Y
S
W
Y
D
A
M
T
Y
N
Y
G
R
Y
H
Q
D
G
L
G
E
Y
N
Y
Q
F
M
Q
P
E
G
D
K
V
P
A
D
N
F
F
A
N
F
N
W
D
K
A
K
N
D
Y
T
I
A
T
A
N
W
I
G
R
N
P
Y
D
V
F
A
G
L
E
L
Q
Q
G
G
S
Y
K
T
K
V
K
W
N
D
I
L
D
E
N
G
K
L
R
L
S
L
G
L
F
A
P
D
T
I
T
S
L
G
K
T
G
E
D
Y
H
K
N
E
D
I
F
F
T
G
Y
Q
G
D
P
T
G
Q
K
P
G
D
K
D
W
Y
G
I
A
N
L
V
A
D
R
T
P
A
V
G
N
T
F
T
T
S
F
N
T
G
H
G
K
K
W
F
V
D
G
K
V
S
K
D
S
E
W
N
Y
R
S
V
S
G
V
L
P
T
W
R
W
W
Q
T
S
T
G
E
K
L
R
A
E
Y
D
F
T
D
A
Y
N
G
G
N
S
L
K
F
S
G
D
V
A
G
K
T
D
Q
D
V
R
L
Y
S
T
K
L
E
V
T
E
K
T
K
L
R
V
A
H
K
G
G
K
G
S
K
V
Y
M
A
F
S
T
T
P
D
Y
K
F
D
D
A
D
A
W
K
E
L
T
L
S
D
N
W
T
N
E
E
F
D
L
S
S
L
A
G
K
T
I
Y
A
V
K
L
F
F
E
H
E
G
A
V
K
D
Y
-
Q
F
N
L
G
Q
L
T
I
S
D
N
H
Q
E
P
Q
S
P
T
S
F
S
V
V
K
Q
S
L
K
N
A
Q
E
A
E
A
V
V
Q
F
K
G
N
K
D
A
D
F
Y
E
V
Y
E
K
D
G
D
S
W
K
L
L
T
G
S
S
-
S
T
T
I
Y
L
P
K
V
S
R
S
A
S
A
Q
G
T
T
Q
E
L
K
V
V
A
V
G
K
N
G
V
R
S
E
A
A
T
T
T
F
D
W
G
M
T
V
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
55.86
32%
66
- C4 -
-
2VTF
4
?
B:
[7-617]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
Y
N
G
P
L
S
S
H
W
F
-
P
E
E
L
A
Q
W
E
P
D
S
D
P
D
A
P
F
N
R
S
H
V
P
L
E
P
G
R
V
A
D
R
V
N
A
N
A
D
T
D
A
H
L
V
S
L
S
A
L
N
R
H
T
S
G
V
P
S
Q
G
A
P
V
F
Y
E
N
T
F
S
Y
W
H
Y
T
D
L
M
V
Y
W
-----
A
G
SAGEGI
I
V
P
--
P
S
A
D
V
I
D
A
S
H
R
N
G
V
P
I
L
G
N
V
F
F
P
P
T
V
Y
G
G
Q
L
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W
L
E
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M
L
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Q
E
E
D
G
S
F
P
L
A
D
K
L
L
E
V
A
D
Y
Y
G
F
D
G
W
F
I
N
Q
Q
T
E
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A
D
-
E
G
T
A
E
A
M
Q
A
F
L
V
Y
L
Q
E
Q
K
P
---
E
G
M
H
I
M
W
Y
D
S
M
I
D
T
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A
I
A
W
Q
N
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L
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N
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M
Y
L
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V
-
A
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L
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F
W
W
R
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R
--
Q
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N
E
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A
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A
L
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P
Y
D
L
Y
A
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V
D
V
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A
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T
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T
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-
V
Q
W
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L
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A
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L
G
L
Y
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A
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T
G
N
P
A
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-
Q
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M
A
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A
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S
G
A
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A
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K
T
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E
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E
W
N
N
R
S
L
Q
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V
L
P
T
W
R
W
I
Q
H
--
G
G
D
L
E
A
T
F
S
W
E
E
A
F
E
G
G
S
S
L
Q
W
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L
A
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A
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Y
Q
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T
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L
T
W
T
F
K
S
E
H
G
N
D
L
N
V
G
F
R
L
D
G
E
E
D
F
R
-
Y
V
E
G
E
Q
R
E
S
I
N
G
W
T
Q
W
T
L
P
L
D
A
F
A
G
Q
T
I
T
G
L
A
F
A
A
E
G
N
E
-
T
G
L
A
-
E
F
Y
I
G
Q
L
A
V
G
A
D
S
E
K
P
A
A
P
N
V
N
V
R
Q
Y
----
D
P
D
P
S
G
I
Q
L
V
W
E
K
Q
S
N
V
H
H
Y
R
V
Y
K
E
----
K
-
E
L
I
G
T
S
A
G
D
R
I
Y
L
E
G
L
V
E
E
S
--
K
Q
N
D
V
R
L
H
I
E
A
L
S
E
T
F
V
P
S
D
A
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_CBE
52.30
33%
65
- C4 -
-
2VTF
4
?
B:
[19-588]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
L
A
Q
W
E
P
D
S
D
P
D
A
P
F
N
R
S
H
V
P
L
E
P
G
R
V
A
D
R
V
N
A
N
A
D
T
D
A
H
L
V
S
L
S
A
L
N
R
H
T
S
G
V
P
S
Q
G
A
P
V
F
Y
E
N
T
F
S
Y
W
H
Y
T
D
L
M
V
Y
W
AGSAG
E
G
------
I
-
I
VP
P
S
A
D
V
I
D
A
S
H
R
N
G
V
P
I
L
G
N
V
F
F
P
P
T
V
Y
G
G
Q
L
E
W
L
E
Q
M
L
E
Q
E
E
D
G
S
F
P
L
A
D
K
L
L
E
V
A
D
Y
Y
G
F
D
G
W
F
I
N
Q
Q
T
E
G
-
A
D
E
G
T
A
E
A
M
Q
A
F
L
V
Y
L
Q
E
Q
K
P
E
G
M
H
I
M
---
W
Y
D
S
M
I
D
T
G
A
I
A
W
Q
N
H
L
T
D
R
N
K
M
Y
L
Q
N
G
S
T
R
V
-
A
D
S
M
F
L
N
F
W
W
R
D
Q
R
Q
S
N
E
L
A
Q
A
--
L
G
R
S
P
Y
D
L
Y
A
G
V
D
V
E
A
R
G
T
-
S
T
P
V
Q
W
E
G
L
F
P
E
G
E
K
A
H
T
S
L
G
L
Y
R
P
D
W
A
F
Q
S
S
E
T
M
E
A
F
Y
E
K
E
L
Q
F
W
V
G
S
T
G
N
P
A
-
E
T
D
G
Q
S
N
W
P
G
M
A
H
W
F
P
A
K
S
T
A
T
S
V
P
F
V
T
H
F
N
T
G
S
G
A
Q
F
S
A
E
G
K
T
V
S
E
Q
E
W
N
N
R
S
L
Q
D
V
L
P
T
W
R
W
I
Q
--
H
G
G
D
L
E
A
T
F
S
W
E
E
A
F
E
G
G
S
S
L
Q
W
H
G
S
L
A
E
G
E
H
A
Q
I
E
L
Y
Q
T
E
L
P
I
S
E
G
T
S
L
T
W
T
F
K
S
E
H
G
N
D
L
N
V
G
F
R
L
D
G
E
E
D
F
R
Y
V
E
G
E
Q
R
E
S
I
-
N
G
W
T
Q
W
T
L
P
L
D
A
F
A
G
Q
T
I
--
T
G
L
A
F
A
A
E
G
N
E
T
G
L
A
E
F
Y
I
G
Q
L
A
V
G
A
D
S
E
K
P
A
A
P
N
--
V
N
V
R
Q
Y
D
P
D
P
S
G
I
Q
L
V
W
E
K
Q
S
N
--
V
H
H
Y
R
V
Y
K
E
----
K
E
L
I
G
T
S
A
-
G
D
R
I
Y
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
52.01
33%
66
- C4 -
-
2VTF
4
?
A:
[19-588]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
L
A
Q
W
E
P
D
S
D
P
D
A
P
F
N
R
S
H
V
P
L
E
P
G
R
V
A
D
R
V
N
A
N
A
D
T
D
A
H
L
V
S
L
S
A
L
N
R
H
T
S
G
V
P
S
Q
G
A
P
V
F
Y
E
N
T
F
S
Y
W
H
Y
T
D
L
M
V
Y
W
A
G
S
AG
E
G
------
I
-
I
VP
P
S
A
D
V
I
D
A
S
H
R
N
G
V
P
I
L
G
N
V
F
F
P
P
T
V
Y
G
G
Q
L
E
W
L
E
Q
M
L
E
Q
E
E
D
G
S
F
P
L
A
D
K
L
L
E
V
A
D
Y
Y
G
F
D
G
W
F
I
N
Q
Q
T
E
G
-
A
D
E
G
T
A
E
A
M
Q
A
F
L
V
Y
L
Q
E
Q
K
P
E
G
M
H
I
M
---
W
Y
D
S
M
I
D
T
G
A
I
A
W
Q
N
H
L
T
D
R
N
K
M
Y
L
Q
N
G
S
T
R
V
-
A
D
S
M
F
L
N
F
W
W
R
D
Q
R
Q
S
N
E
L
A
Q
A
--
L
G
R
S
P
Y
D
L
Y
A
G
V
D
V
E
A
R
G
T
-
S
T
P
V
Q
W
E
G
L
F
P
E
G
E
K
A
H
T
S
L
G
L
Y
R
P
D
W
A
F
Q
S
S
E
T
M
E
A
F
Y
E
K
E
L
Q
F
W
V
G
S
T
G
N
P
A
-
E
T
D
G
Q
S
N
W
P
G
M
A
H
W
F
P
A
K
S
T
A
T
S
V
P
F
V
T
H
F
N
T
G
S
G
A
Q
F
S
A
E
G
K
T
V
S
E
Q
E
W
N
N
R
S
L
Q
D
V
L
P
T
W
R
W
I
Q
--
H
G
G
D
L
E
A
T
F
S
W
E
E
A
F
E
G
G
S
S
L
Q
W
H
G
S
L
A
E
G
E
H
A
Q
I
E
L
Y
Q
T
E
L
P
I
S
E
G
T
S
L
T
W
T
F
K
S
E
H
G
N
D
L
N
V
G
F
R
L
D
G
E
E
D
F
R
Y
V
E
G
E
Q
R
E
S
I
-
N
G
W
T
Q
W
T
L
P
L
D
A
F
A
G
Q
T
I
--
T
G
L
A
F
A
A
E
G
N
E
T
G
L
A
E
F
Y
I
G
Q
L
A
V
G
A
D
S
E
K
P
A
A
P
N
--
V
N
V
R
Q
Y
D
P
D
P
S
G
I
Q
L
V
W
E
K
Q
S
N
--
V
H
H
Y
R
V
Y
K
E
T
K
H
G
K
E
L
I
G
T
S
A
-
G
D
R
I
Y
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
49.48
33%
0
- C- -
-
3FHQ
2
?
A:
[14-589]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
L
A
Q
W
E
P
D
S
D
P
D
A
P
F
N
R
S
H
V
P
L
E
P
G
R
V
A
D
R
V
N
A
N
A
D
K
D
A
H
L
V
S
L
S
A
L
N
R
H
T
S
G
V
P
S
Q
G
A
P
V
F
Y
E
N
T
F
S
Y
W
H
Y
T
D
L
M
V
Y
W
A
G
S
AG
E
G
------
I
-
I
VP
P
S
A
D
V
I
D
A
S
H
R
N
G
V
P
I
L
G
N
V
F
F
P
P
T
V
Y
G
G
Q
L
E
W
L
E
Q
M
L
E
Q
E
E
D
G
S
F
P
L
A
D
K
L
L
E
V
A
D
Y
Y
G
F
D
G
W
F
I
N
Q
E
T
E
G
-
A
D
E
G
T
A
E
A
M
Q
A
F
L
V
Y
L
Q
E
Q
K
P
E
G
M
H
I
M
---
W
Y
D
S
M
I
D
T
G
A
I
A
W
Q
N
H
L
T
D
R
N
K
M
Y
L
Q
N
G
S
T
R
V
-
A
D
S
M
F
L
N
F
W
W
R
D
Q
R
Q
S
N
E
L
A
Q
A
--
L
G
R
S
P
Y
D
L
Y
A
G
V
D
V
E
A
R
G
T
-
S
T
P
V
Q
W
E
G
L
F
P
E
G
E
K
A
H
T
S
L
G
L
Y
R
P
D
W
A
F
Q
S
S
E
T
M
E
A
F
Y
E
K
E
L
Q
F
W
V
G
S
T
G
N
P
A
-
E
T
D
G
Q
S
N
W
P
G
M
A
H
W
F
P
A
K
S
T
A
T
S
V
P
F
V
T
H
F
N
T
G
S
G
A
Q
F
S
A
E
G
K
T
V
S
E
Q
E
W
N
N
R
S
L
Q
D
V
L
P
T
W
R
W
I
Q
--
H
G
G
D
L
E
A
T
F
S
W
E
E
A
F
E
G
G
S
S
L
Q
W
H
G
S
L
A
E
G
E
H
A
Q
I
E
L
Y
Q
T
E
L
P
I
S
E
G
T
S
L
T
W
T
F
K
S
E
H
D
N
D
L
N
V
G
F
R
L
D
---
D
F
R
Y
V
E
G
E
Q
R
E
S
I
-
N
G
W
T
Q
W
T
L
P
L
D
A
F
A
G
Q
T
I
--
T
G
L
A
F
A
A
E
G
N
E
T
G
L
A
E
F
Y
T
G
Q
L
A
V
G
----
K
P
A
A
P
N
--
V
N
V
R
Q
Y
D
P
D
P
S
G
I
Q
L
V
W
E
K
Q
S
N
--
V
H
H
Y
R
V
Y
K
E
T
K
H
G
K
E
L
I
G
T
S
A
-
G
D
R
I
Y
I
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
47.52
99%
-47
- C4 -
-
2XQX
-
?
A:
[5-150]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
S
N
I
V
P
G
A
T
V
I
D
S
T
F
P
K
T
E
G
G
E
G
I
E
G
M
L
N
G
T
I
T
----
S
L
S
D
K
W
S
S
A
Q
--
L
S
G
S
V
D
I
R
L
T
K
P
R
T
V
V
R
W
V
M
D
H
A
G
A
G
G
E
-----
S
V
N
D
G
L
M
N
T
K
D
F
D
L
----------
Y
Y
K
D
A
D
G
E
W
K
L
A
K
E
V
R
G
--------
N
K
--
A
H
-
V
T
D
I
T
L
-
D
K
P
I
T
A
Q
D
W
R
L
N
V
V
T
S
D
N
G
--
T
P
W
K
A
I
R
I
Y
N
W
K
M
Y
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
47.30
95%
-44
- C4 -
-
2XQX
-
?
A:
[5-151]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
S
N
I
V
P
G
A
T
V
I
D
S
T
F
P
K
T
E
G
G
E
G
I
E
G
M
L
N
G
T
I
T
----
S
L
S
D
K
W
S
S
A
Q
--
L
S
G
S
V
D
I
R
L
T
K
P
R
T
V
V
R
W
V
M
D
H
A
G
A
G
G
E
-----
S
V
N
D
G
L
M
N
T
K
D
F
D
L
----------
Y
Y
K
D
A
D
G
E
W
K
L
A
K
E
V
R
G
--------
N
K
--
A
H
-
V
T
D
I
T
L
-
D
K
P
I
T
A
Q
D
W
R
L
N
V
V
T
S
D
N
G
--
T
P
W
K
A
I
R
I
Y
N
W
K
M
Y
E
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
Fugue
38.45
97%
-37
- C2 -
-
2L7Y
-
?
A:
[1-89]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
P
K
T
I
L
G
I
E
V
S
Q
E
P
K
K
D
Y
L
V
G
D
S
L
D
L
S
E
G
R
F
A
V
A
Y
S
N
D
T
M
E
E
H
S
F
T
D
E
G
V
E
I
S
G
Y
D
A
Q
K
T
G
R
Q
T
L
T
L
H
Y
Q
G
H
E
V
S
F
D
V
L
V
S
P
K
A
A
L
N
D
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
38.45
97%
-37
* C2 *
-
2L7Y
-
?
A:
[1-89]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
P
K
T
I
L
G
I
E
V
S
Q
E
P
K
K
D
Y
L
V
G
D
S
L
D
L
S
E
G
R
F
A
V
A
Y
S
N
D
T
M
E
E
H
S
F
T
D
E
G
V
E
I
S
G
Y
D
A
Q
K
T
G
R
Q
T
L
T
L
H
Y
Q
G
H
E
V
S
F
D
V
L
V
S
P
K
A
A
L
N
D
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
HHSearch
38.14
98%
-41
- C2 -
-
2L7Y
-
?
A:
[2-84]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
K
T
I
L
G
I
E
V
S
Q
E
P
K
K
D
Y
L
V
G
D
S
L
D
L
S
E
G
R
F
A
V
A
Y
S
N
D
T
M
E
E
H
S
F
T
D
E
G
V
E
I
S
G
Y
D
A
Q
K
T
G
R
Q
T
L
T
L
H
Y
Q
G
H
E
V
S
F
D
V
L
V
S
P
K
A
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
HHSearch
37.94
35%
-50
- C2 -
-
2L7Y
-
?
A:
[2-82]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
K
T
I
L
G
I
E
V
S
Q
E
P
-
K
K
D
Y
L
V
G
D
S
L
D
L
S
E
G
R
F
A
V
A
Y
S
N
D
T
M
E
E
-
H
S
F
T
D
E
G
V
E
I
S
G
Y
D
A
Q
K
T
G
R
Q
T
L
T
L
H
Y
Q
G
H
E
--
V
S
F
D
V
L
V
S
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
HHSearch
31.52
14%
-30
- C4 -
-
3UES
-
?
B:
[365-477]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
A
S
A
A
A
A
H
L
V
D
G
N
R
-------
D
T
F
W
R
P
D
A
DD
A
A
P
A
I
T
L
T
L
P
Q
P
T
T
I
N
A
I
V
I
E
E
A
I
E
H
G
------------
Q
R
I
E
H
L
R
V
----------
T
G
A
L
P
D
G
T
E
R
V
L
G
Q
A
G
T
--------
V
---
G
Y
-
R
R
I
L
R
F
-
D
-
D
V
E
V
S
S
V
T
L
H
V
D
G
S
R
-------
L
A
P
M
I
S
R
A
A
A
V
R
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
27.30
12%
-1
* C4 *
-
1GQP
-
APC10_YEAST
A:
[68-194]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
G
N
P
V
D
F
A
L
D
D
N
Y
-------
D
T
F
W
Q
S
D
G
G-
Q
P
H
Q
L
D
I
M
F
S
K
R
M
D
I
C
V
M
A
I
F
F
S
M
I
A
D
----------
E
S
Y
A
P
S
L
V
K
V
----------
Y
A
G
H
S
P
S
D
A
R
F
Y
K
M
L
E
V
--------
R
N
V-
N
G
-
W
V
A
L
R
F
L---
L
K
C
Q
F
I
R
L
L
F
P
V
N
H
E
N
--
G
--
K
D
T
H
L
R
G
I
R
L
Y
V
P
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
HHSearch
25.10
17%
35
- C4 -
-
4NUZ
-
?
A:
[667-829]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
M
V
N
L
A
E
G
A
T
V
I
G
G
S
A
----
D
P
V
N
A
R
K
V
F
D
G
Q
L
G
SETD
N
I
S
L
G
W
D
S
-----
K
Q
S
I
I
F
K
L
K
E
D
G
L
I
K
H
W
R
F
F
N
D
S
A
R
N
P
ETTNK
P
I
Q
E
A
S
L
Q
I
F
N
I
K
D
YN
L
D
N
L
L
E
NP
N
K
F
D
D
E
K
Y
W
I
T
V
D
T
Y
S
A
--------
Q
G
ER
A
T
-
A
F
S
N
T
L
--
N
N
I
T
S
K
Y
W
R
V
V
F
D
T
K
G
D
R
----
Y
S
S
P
V
V
P
E
L
Q
I
L
G
Y
P
L
P
N
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
HHSearch
23.28
15%
34
- C4 -
-
4A3Z
-
?
A:
[26-161]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
V
N
I
A
E
N
K
N
V
S
G
S
N
S
---
Q
S
G
N
P
L
S
N
I
T
D
G
D
L
-------
S
S
L
W
I
S
D
N
GA
M
P
A
N
A
T
I
D
L
E
G
N
N
F
V
D
F
L
E
L
H
F
E
K
E
G
--------------
F
R
F
Q
F
K
V
----------
E
V
E
D
E
S
G
N
R
E
T
V
L
D
M
T
S
--------
N
T
--
E
D
N
K
K
S
Y
N
I
-
P
V
K
K
E
I
S
K
I
H
A
T
I
T
G
K
A
P
G
GS
F
D
Q
A
W
A
A
I
A
E
I
K
A
M
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
HHSearch
22.68
14%
67
- C4 -
-
4LPL
-
?
A:
[61-182]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
D
E
P
S
K
A
V
D
G
D
D
-------
S
S
Q
F
H
S
Q
D
SA
I
D
K
P
F
I
I
D
M
Q
K
A
Y
T
I
E
K
L
E
L
L
F
R
K
N
G
N
------------
G
S
V
K
R
A
E
I
----------
Y
S
S
L
D
G
V
T
Y
E
K
V
F
S
N
A
E
GSD
I
A
P
W
A
T
D
--
G
E
-
V
K
T
I
N
F
-
N
K
P
I
K
V
R
Y
F
K
I
V
T
K
E
S
I
G
------
N
F
L
A
M
R
E
F
R
P
Y
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------