@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : spr0486: (2017-12-23 )
MTDERIHILRDILLELHNGASPESVQDRFDATFTGVSAIEISLMEHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVLDTEHPGHPVRVFKEENLALRAALIRIRRLLDTYELMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGHDSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESILLMILLESFTQDDWIQIAEESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEGQVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFVNKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKAIMKGLREGTKDKYEMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE
Atome Classification :
(20 SA)
-------.........10.----.......---------------------20..-......30..-......40........50-------.......--..60....---.....70........80----.......-.90...-.....100.....---..110.......-----120.......130-....--...-.-.----140........150.......160-......--------...170..-....---.180..--.....----190----........--200....----...210.---......220--......-------------------------...230.......240...---.-------...250.----......260.-----........270.......280...-....290---.------------........300.------------.......310.......320.......330....---..-----.340.....-..350.------......360..----.....370.-..-..-..380.......390...--..-..400..-.....410...-....420....----...430.......440.----.-------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
-------MT
D
E
R
I
H
I
L
R
D
I
----
L
L
E
L
HNG---------------------AS
P
E
-
S
V
Q
D
R
F
D
A
T
F-TG
V
S
A
I
E
I
S
L
M
E
H
E
LMN--------SDSGV
T
F
--
E
D
V
-
M
E
L
C
---
D
V
H
A
N
L
F
K
N
A
IKG
V
E
V
L----DTEHPGH-
P
V
R
V
F
K-EE
N
L
A
L
R
A
A
L
I
R
I
---
R
R
L
L
D
T
Y
E
LM
E
D
-----
E
E
M
L
A
E
M
R
K
G
L
---
V
R
Q
M--GLV-G-
Q
----
F
-
D
I
H
Y
Q
R
K
E
E
L
F
F
P
I
M
E
R
YGH---DSPP
K
V
--------
M
WGV
D
D
Q
I
-
R
E
L
F
---
Q
T
A
L
T
T
--
A
KSLP----E
V
-----
S
I
S
S
V
K
E
A
--
F
E
A
F
A
T
E
----
F
E
S
M
I
FK---EES
I
L
L
M
----
I
L
L
E
S
F-------------------------TQ
D
D
W
I
Q
I
AEESDAY
G
Y
A
I
---I-------RPSEKW
V
----
P
E
R
Q
S
F
I
--
E
-----
E
K
I
AEEPVQLDTAE
G
Q
V
Q
Q
VIDTP-EG
H
F
T
-----
I
------------
T
FTP
K
E
K
E
A
V
-
L
------------
D
R
H
S
Q
Q
A
FGN
G
Y
L
S
V
E
Q
A
N
L
I
L
NHLP
M
E
I
T
F
V
N
K
---
E
D
-----
I
F
Q
Y
YNDNT-P
A
D
E
M
I
------
F
KR
T
P
S
QVGRN----VELCHP
P
K
Y
-
L
D
-
K
V
-
K
A
I
M
K
G
L
R
EGT
K
D
K
Y
E
M
W--FK-SESRG
K
F
-
V
H
I
T
Y
A
A
V
HDE-DG
E
F
Q
G
V
L
E
Y
V
----
Q
DI
Q
P
Y
R
EI
D
T
D
Y
FRGL----E-------------------------------------------------------------------------
27
Fugue
83.39
73%
-87
- C5 -
-
2QKP
-
?
A:
[2-139]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
-
L
------------
D
R
T
T
Q
Q
P
F
G
N
G
Y
L
S
V
E
Q
A
N
L
I
L
N
H
L
P
L
E
I
T
F
V
N
K
---
D
D
-----
I
F
Q
Y
Y
N
D
S
V
-
P
A
A
E
M
V
------
F
K
R
T
P
S
Q
V
G
R
N
----
V
E
L
C
H
P
P
K
V
-
L
D
-
K
V
-
K
K
V
F
E
L
L
R
N
G
Q
R
D
K
V
N
M
W
--
F
Q
-
S
E
R
L
G
K
F
-
V
Y
V
T
Y
A
A
V
R
D
Q
-
A
G
D
F
Q
G
V
L
E
Y
V
----
Q
D
I
K
P
F
F
E
L
D
S
E
-----------------------------------------------------------------------------------
21
PsiBlast_PDB
82.94
73%
-87
- C5 -
-
2QKP
-
?
A:
[3-139]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
------------
D
R
T
T
Q
Q
P
F
G
N
G
Y
L
S
V
E
Q
A
N
L
I
L
N
H
L
P
L
E
I
T
F
V
N
K
---
D
D
-----
I
F
Q
Y
Y
N
D
S
V
-
P
A
A
E
M
V
------
F
K
R
T
P
S
Q
V
G
R
N
----
V
E
L
C
H
P
P
K
V
-
L
D
-
K
V
-
K
K
V
F
E
L
L
R
N
G
Q
R
D
K
V
N
M
W
--
F
Q
-
S
E
R
L
G
K
F
-
V
Y
V
T
Y
A
A
V
R
D
Q
-
A
G
D
F
Q
G
V
L
E
Y
V
----
Q
D
I
K
P
F
F
E
L
D
S
E
-----------------------------------------------------------------------------------
7
HHSearch
82.62
73%
-94
- C5 -
-
2QKP
-
?
A:
[7-139]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
Q
Q
P
F
G
N
G
Y
L
S
V
E
Q
A
N
L
I
L
N
H
L
P
L
E
I
T
F
V
N
K
---
D
D
-----
I
F
Q
Y
Y
N
D
S
V
-
P
A
A
E
M
V
------
F
K
R
T
P
S
Q
V
G
R
N
----
V
E
L
C
H
P
P
K
V
-
L
D
-
K
V
-
K
K
V
F
E
L
L
R
N
G
Q
R
D
K
V
N
M
W
--
F
Q
-
S
E
R
L
G
K
F
-
V
Y
V
T
Y
A
A
V
R
D
Q
-
A
G
D
F
Q
G
V
L
E
Y
V
----
Q
D
I
K
P
F
F
E
L
D
S
E
-----------------------------------------------------------------------------------
25
PsiBlast_CBE
82.61
73%
-76
- C5 -
-
2QKP
1
?
B:
[3-140]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
------------
D
R
T
T
Q
Q
P
F
G
N
G
Y
L
S
V
E
Q
A
N
L
I
L
N
H
L
P
L
E
I
T
F
V
N
K
---
D
D
-----
I
F
Q
Y
Y
N
D
S
V
-
P
A
A
E
M
V
------
F
K
R
T
P
S
Q
V
G
R
N
----
V
E
L
C
H
P
P
K
V
-
L
D
-
K
V
-
K
K
V
F
E
L
L
R
N
G
Q
R
D
K
V
N
M
W
--
F
Q
-
S
E
R
L
G
K
F
-
V
Y
V
T
Y
A
A
V
R
D
Q
-
A
G
D
F
Q
G
V
L
E
Y
V
----
Q
D
I
K
P
F
F
E
L
D
S
E
F
----------------------------------------------------------------------------------
23
PsiBlast_CBE
82.20
73%
-89
- C5 -
-
2QKP
1
?
D:
[4-137]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
R
T
T
Q
Q
P
F
G
N
G
Y
L
S
V
E
Q
A
N
L
I
L
N
H
L
P
L
E
I
T
F
V
N
K
---
D
D
-----
I
F
Q
Y
Y
N
D
S
V
-
P
A
A
E
M
V
------
F
K
R
T
P
S
Q
V
G
R
N
----
V
E
L
C
H
P
P
K
V
-
L
D
-
K
V
-
K
K
V
F
E
L
L
R
N
G
Q
R
D
K
V
N
M
W
--
F
Q
-
S
E
R
L
G
K
F
-
V
Y
V
T
Y
A
A
V
R
D
Q
-
A
G
D
F
Q
G
V
L
E
Y
V
----
Q
D
I
K
P
F
F
E
L
D
-------------------------------------------------------------------------------------
24
PsiBlast_CBE
79.86
73%
-71
- C5 -
-
2QKP
1
?
C:
[3-140]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
------------
D
R
T
T
Q
Q
P
F
G
N
G
Y
L
S
V
E
Q
A
N
L
I
L
N
H
L
P
L
E
I
T
F
V
N
K
---
D
D
-----
I
F
Q
Y
Y
N
D
S
V
-
P
A
A
E
M
V
------
F
K
R
T
P
S
Q
V
G
R
N
----
V
E
L
C
H
P
P
K
V
-
L
D
-
K
V
-
K
K
V
F
E
L
L
R
N
G
Q
R
D
K
V
N
M
W
--
F
Q
-
S
E
R
L
G
K
F
-
V
Y
V
T
Y
A
A
V
R
D
Q
-
A
G
D
F
Q
G
V
L
E
Y
V
----
Q
D
I
K
P
F
F
E
L
D
S
E
F
----------------------------------------------------------------------------------
22
PsiBlast_PDB
77.15
30%
16
- C- -
-
3CAX
-
?
A:
[122-465]
------------------------------------------------------------------------------------------------------------------------------------------
G
H
-
P
L
K
T
L
Y
-
Q
E
N
K
E
I
M
K
D
A
E
M
L
---
N
L
Y
A
K
T
L
A
T
T
K
D
-----
E
R
M
R
E
E
I
L
G
V
L
E
E
I
V
S
S
L
--
R
M
V
-
G
-
F
-------
T
H
Y
N
R
E
E
M
L
I
F
P
Y
I
E
R
R
G
L
---
T
V
I
A
T
V
--------
L
W
T
K
H
D
E
I
-
R
A
M
I
---
K
Q
L
A
E
L
--
L
R
K
R
E
----
E
M
-----
P
W
E
E
F
V
E
K
--
F
K
A
K
A
G
E
V
A
F
A
L
S
D
M
V
F
R
---
E
N
N
I
F
Y
P
----
T
L
K
A
L
L
-------------------------
S
E
G
E
W
K
A
I
K
M
Q
E
D
E
I
G
Y
Y
K
---
V
-------
K
P
P
E
-
W
D
----
P
G
-------
E
-----
D
V
K
P
L
H
P
W
E
I
N
-
P
E
L
N
V
E
Q
L
L
T
L
P
K
E
V
Q
Q
A
-----
L
------------
R
G
Q
P
L
E
F
D
K
T
Q
L
------------
K
R
E
E
D
I
D
L
G
T
G
Y
L
N
I
E
E
L
K
A
I
F
E
A
L
P
V
D
V
T
F
I
D
K
---
D
D
-----
R
V
R
F
F
S
P
G
-----
E
R
I
------
F
T
R
T
P
S
V
L
G
R
P
----
V
Q
L
C
H
P
P
K
S
-
V
Y
-
V
V
-
N
K
I
L
K
A
F
K
E
G
R
K
K
E
A
T
F
W
--
L
R
---
L
R
E
K
Y
-
V
Y
I
K
Y
V
P
L
F
N
E
-
K
G
E
Y
I
G
T
L
E
M
T
----
M
D
I
A
P
Y
K
K
I
E
-------------------------------------------------------------------------------------
1
HHSearch
68.95
27%
29
- C- -
-
3CAX
-
?
A:
[119-467]
---------------------------------------------------------------------------------------------------------------------------------------
L
P
E
G
H
-
P
L
K
T
L
Y
-
Q
E
N
K
E
I
M
K
D
A
E
M
L
---
N
L
Y
A
K
T
L
A
T
T
K
D
-----
E
R
M
R
E
E
I
L
G
V
L
---
E
E
I
V
--
S
S
L
-
R
-
M
----
V
G
F
T
H
Y
N
R
E
E
M
L
I
F
P
Y
I
E
R
R
G
L
---
T
V
I
A
T
V
--------
L
W
T
K
H
D
E
I
-
R
A
M
I
---
K
Q
L
A
E
L
--
L
R
K
R
E
----
E
M
P
W
E
E
-
F
V
E
K
F
K
A
K
--
A
G
E
V
A
F
A
----
L
S
D
M
V
F
R
---
E
N
N
I
F
Y
P
----
T
L
K
A
L
L
-------------------------
S
E
G
E
W
K
A
I
K
M
Q
E
D
E
I
G
Y
Y
K
---
V
--------
K
P
P
E
W
D
----
P
G
E
D
V
K
P
L
H
P
-----
W
E
I
N
P
E
L
N
V
E
Q
L
L
T
--
L
P
K
E
-----
V
Q
Q
A
L
-----
R
------------
G
Q
P
L
E
F
D
K
T
Q
-
L
------------
K
R
E
E
D
I
D
L
G
T
G
Y
L
N
I
E
E
L
K
A
I
F
E
A
L
P
V
D
V
T
F
I
D
K
---
D
D
-----
R
V
R
F
F
S
P
G
E
----
R
I
F
------
T
-
R
T
P
S
V
L
G
R
P
----
V
Q
L
C
H
P
P
K
S
-
V
Y
-
V
V
-
N
K
I
L
K
A
F
K
E
G
R
K
K
E
A
T
F
W
--
L
R
-
L
R
--
E
K
Y
-
V
Y
I
K
Y
V
P
L
F
N
E
-
K
G
E
Y
I
G
T
L
E
M
T
----
M
D
I
A
P
Y
K
K
I
E
G
E
-----------------------------------------------------------------------------------
26
Fugue
66.73
27%
57
- C- -
-
3CAX
-
?
A:
[119-473]
---------------------------------------------------------------------------------------------------------------------------------------
L
P
E
G
H
-
P
L
K
T
L
Y
-
Q
E
N
K
E
I
M
K
D
A
E
M
L
---
N
L
Y
A
K
T
L
A
T
T
K
D
-----
E
R
M
R
E
E
I
L
G
V
L
---
E
E
I
V
--
S
S
L
R
M
-
V
----
G
-
F
T
H
Y
N
R
E
E
M
L
I
F
P
Y
I
E
R
R
G
L
---
T
V
I
A
T
V
--------
L
W
T
K
H
D
E
I
-
R
A
M
I
---
K
Q
L
A
E
L
--
L
R
K
R
E
EMP
W
E
E
-----
F
V
E
K
F
K
A
K
--
A
G
E
V
A
F
A
----
L
S
D
M
V
F
R
---
E
N
N
I
F
Y
P
----
T
L
K
A
L
L
-------------------------
S
E
G
E
W
K
A
I
K
M
Q
E
D
E
I
G
Y
Y
K
---
V
-------
K
P
P
E
W
D
P
----
G
E
D
V
K
P
L
--
H
-----
P
W
E
I
N
P
E
L
N
V
E
Q
L
L
T
L
P
K
E
V
Q
Q
A
L
-
R
G
Q
----------------------
P
L
E
F
D
K
T
Q
-
L
------------
K
R
E
E
D
I
D
L
G
T
G
Y
L
N
I
E
E
L
K
A
I
F
E
A
L
P
V
D
V
T
F
I
D
K
---
D
D
-----
R
V
R
F
F
S
P
G
-----
E
R
I
------
F
T
R
T
P
S
V
L
G
R
P
----
V
Q
L
C
H
P
P
K
S
-
V
Y
-
V
V
-
N
K
I
L
K
A
F
K
E
G
R
K
K
E
A
T
F
W
--
L
R
-
L
R
--
E
K
Y
-
V
Y
I
K
Y
V
P
L
F
N
E
-
K
G
E
Y
I
G
T
L
E
M
T
----
M
D
I
A
P
Y
K
K
I
E
G
E
K
R
L
L
D
----
W
-------------------------------------------------------------------------
29
Fugue
44.65
16%
-33
- C5 -
-
2GJ3
1
NIFL_AZOVI
A:
[2-120]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
L
P
E
I
F
R
Q
T
V
E
H
A
P
I
A
I
S
I
T
D
L
---
K
A
-----
N
I
L
Y
A
N
--
R
-
A
F
R
T
I
T
------
G
Y
G
S
E
E
V
L
G
K
N
----
E
S
I
L
S
N
G
T
T
P
R
L
-
V
Y
-
Q
A
L
W
G
R
L
A
Q
K
K
P
W
S
G
V
L
V
--
N
R
-
R
K
D
K
T
L
Y
L
A
E
L
T
V
A
P
V
L
N
E
-
A
G
E
T
I
Y
Y
L
G
M
H
----
R
D
T
S
E
L
H
----------------------------------------------------------------------------------------
2
HHSearch
43.49
14%
-65
* C4 *
-
2P0N
2
?
A:
[12-167]
---------------------------------------------------------------------------------------------------------------------------------------
V
T
F
A
E
-
P
I
E
M
L
Y
-
A
C
H
G
K
V
R
R
F
C
G
Q
V
---
A
M
L
S
D
Y
I
A
E
N
G
C
-----
N
---
Q
I
V
L
Q
T
I
---
R
Q
I
A
--
Q
Y
F
-
N
V
A
----
A
-
P
L
H
H
E
D
E
E
E
N
F
F
P
L
L
L
Q
Y
A
P
QA-
Q
E
S
V
D
E
--------
L
L
R
Q
H
I
G
L
-
H
D
N
W
---
A
A
V
S
A
E
--
F
A
K
L
E
----
A
D
N----
A
Y
V
P
D
E
E
A
--
F
K
R
F
V
A
G
----
Y
D
V
H
L
A
I
---
E
E
P
-
L
F
D
----
M
G
N
T
F
I
-------------------------
P
K
E
K
L
T
E
I
G
E
I
M
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
Fugue
41.47
16%
56
- C3 -
-
4PXG
-
T2S3_STAAU
A:
[26-509]
-------
T
K
Q
A
V
H
N
R
A
K
E
A
VGKS
V
L
E
L
N
G
G
---------------------
E
S
I
K
S
S
V
G
D
A
F
E
N
W
F
G
V
A
L
K
A
T
P
F
K
K
L
K
N
G
K
Y
S
--------
S
K
E
R
L
V
L
--
N
I
I
N
Y
E
K
V
A
N
E
N
F
E
T
S
S
F
L
S
K
N
N
T
I
E
L
A
----
F
Y
E
Y
I
K
G
-
T
----
P
-
S
D
N
W
I
I
K
E
A
V
L
Y
E
M--
H
K
N
P
I
D
Y
E
I
I
K
Q
D
W
---
E
I
I
N
Q
Y
I
N
E
G
K
---
A
H
E
L
SE
G
L
T
-
S
-
Y
----
L
-
A
P
C
T
K
G
A
N
A
S
S
L
R
N
Q
P
-
Y
S
D
---
I
K
A
K
Q
R
--------
A
F
S
L
K
S
G
Y
M
T
S
I
L
---
R
K
Y
V
L
G
--
D
E
K
I
D
----
S
I
---------
V
K
D
P
--
F
E
I
K
E
K
S
----
I
E
D
I
V
F
E
---
K
F
Q
P
Y
I
N
----
W
S
I
D
K
L
-------------------------
C
E
H
F
S
I
N
K
G
E
K
G
L
N
Y
R
I
A
S
---
A
I
L
NLK
G
K
T
T
K
S
K
P
F
----
P
E
V
E
E
F
E
--
K
-----
S
S
I
V
V
K
T
V
H
F
N
K
-----------
K
-
N
V
N
K
E
-----
S
M
-----------
S
F
G
A
F
K
F
E
E
L
-
A
------------
N
E
E
W
E
D
--
S
E
G
Y
P
S
A
Q
W
R
N
F
L
L
E
--
T
R
F
L
F
F
V
V
K
---
E
D
EDGVD
I
F
K
G
I
K
F
F
S
M
P
E
E
D
I
N
G
P
V
K
R
M
W
D
D
T
V
K
K
L
K
E
G
----
V
T
L
E
A
V
P
----------------
D
K
S
T
K
D
G
W
R
I
K
N
N
F
V
-
D
K
S
D
D
L
I
-
C
H
V
R
P
H
T
N
N
R
D
-
Y
R
G
G
S
N
A
D
K
L
P
----
K
K
I
N
W
I
N
R
P
D
S
D
D
Y
S
D
E
----
W
M
T
K
Q
S
F
W
I
N
N
D
Y
I
K
K
Q
V
EDLL----------------------------------------------------
31
Fugue
41.39
16%
42
- C2 -
-
4WBD
3
BSHC_BACSU
A:
[2-541]
------H
M
Q
L
T
E
L
S
I
K
N
Q
N
----
V
F
V
Q
H
Y
I
---------------------
D
G
K
E
-
E
M
S
S
F
F
D
Y
S
-------
I
H
H
K
D
M
W
R
E
R
L
E
--------
D
L
S
S
R
F
F
A
R
E
E
L
-
A
A
Y
L
---
T
S
Y
H
N
K
F
G
S
S
A
M
Q
S
A
I
E
----
K
L
K
D
P
S
S
-
A
A
V
V
G
G
-
Q
Q
A
G
L
L
T
G
P
L
Y
T
I
---
H
K
I
I
S
I
I
V
L
A
K
Q
-----
Q
E
--
K
E
L
Q
V
P
V
---
I
P
I
F
--
W
V
A
-
G
-
E
DHDL
D
-
E
I
N
F
V
H
T
S
E
E
N
G
P
V
K
K
K
L
P
Q
---
S
Y
W
K
K
S
SAASTSLD
Q
E
K
C
A
A
W
I
-
D
D
V
F
---
A
A
F
E
E
T
DH
T
N
T
L
L
----
D
N
-----
V
K
R
C
L
R
E
S
VT
F
T
D
F
F
E
L
----
L
I
A
D
L
F
Q
---
E
E
G
L
V
L
L
N
SGD
P
G
I
K
K
L
-------------------------
E
T
A
M
F
Q
K
I
L
R
E
N
D
E
L
A
R
A
V
---
S
-------
D
Q
Q
A
F
M
R
----
Q
A
G
Y
K
P
I
--
I
-----
E
S
-
G
K
E
Q
A
N
L
F
Y
E
Y
E
D
E
R
F
L
I
E
K
D
-
N
G
R
F
V
IKELD
L
------------
G
W
T
R
D
E
L
H
T
H
-
M
------------
E
E
H
P
E
R
-
F
S
N
N
V
V
T
---
R
P
L
M
Q
E
F
L
I
P
T
L
A
F
I
A
G
---
P
G
-----
E
I
N
Y
W
G
E
L
K
-
Q
A
F
A
V
M
------
G
F
K
M
P
P
V
M
P
R
L
N
I
T
I
L
E
R
H
I
E
K
K
L
-
A
E
-
R
N
-
I
S
L
Q
D
A
I
E
R
G
T
E
N
Q
R
E
T
Y
--
F
E
-
R
Q
I
P
E
E
F
-
T
A
V
M
D
Q
A
K
S
Q
I
-
E
A
I
H
K
T
V
R
Q
E
A
L
K
V
D
Q
S
L
E
P
L
L
L
K
N
A
A
F
I
Q
D
Q
----
L
Q
F
L
E
R
T
V
M
K
R
I
E
E
K
E
G
Y
V
L
K
D
Y
E
R
I
Q
N
S
IKPLLAPQERIWNI
M
Y
Y
L
N
R
YG
P
K
F
F
T
T
F
K
N
LPFSFQN
Q
H
Q
V
V
K
L
6
HHSearch
40.61
13%
-22
- C4 -
-
5FNP
1
YTFE_ECOLI
A:
[6-218]
-------------
Q
P
L
G
E
L
----
A
L
S
I
P
R
A
---------------------
S
----
A
L
F
R
K
Y
D
M
D
Y
-
A
-
A
G
-
G
-
K
Q
T
L
A
R
A
A
A
R
---------
K
-
E
L
D
V
--
E
V
I
-
E
A
E
L
---
A
K
L
A
E
Q
-
P
I
E
-
K
---
D
W
----
R
S
A
P
L
A
E
-
I
I
D
H
I
I
V
R
Y
H
D
R
H
R
E
Q
L
P
E
L
---
I
L
Q
A
T
K
V
E
R
V
H
A
-----
D
--
K
P
S
V
P
K
G
L
---
T
K
Y
L
--
T
M
L
-
H
E
E
----
L
-
S
S
H
M
M
K
E
E
Q
I
L
F
P
M
I
K
Q
G
M
G
SQA
M
G
P
I
S
V
--------
M
E
S
E
H
D
E
A
-
G
E
L
L
---
E
V
I
K
H
T
--
T
N
N
V
T
----
P
P
PEAC
T
T
W
K
A
M
Y
N
G
--
I
N
E
L
I
D
D
----
L
M
D
H
I
S
L
---
E
N
N
V
L
F
P
----
R
A
L
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
HHSearch
38.70
13%
-26
- C4 -
-
5FNN
1
YTFE_ECOLI
A:
[6-218]
-------------
Q
P
L
G
E
L
----
A
L
S
I
P
R
A
---------------------
S
----
A
L
F
R
K
Y
D
M
D
Y
-
A
-
A
G
-
G
-
K
Q
T
L
A
R
A
A
A
R
---------
K
-
E
L
D
V
--
E
V
I
-
E
A
E
L
---
A
K
L
A
E
Q
-
P
I
E
-
K
---
D
W
----
R
S
A
P
L
A
E
-
I
I
D
H
I
I
V
R
Y
H
D
R
H
R
E
Q
L
P
E
L
---
I
L
Q
A
T
K
V
E
R
V
H
A
-----
D
--
K
P
S
V
P
K
G
L
---
T
K
Y
L
--
T
M
L
-
H
E
E
----
L
-
S
S
H
M
M
K
E
E
Q
I
L
F
P
M
I
K
Q
G
M
G
SQA
M
G
P
I
S
V
--------
M
E
S
E
H
D
E
A
-
G
E
L
L
---
E
V
I
K
H
T
--
T
N
N
V
T
----
P
P
PEAC
T
T
W
K
A
M
Y
N
G
--
I
N
E
L
I
D
D
----
L
M
D
H
I
S
L
---
E
N
N
V
L
F
P
----
R
A
L
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
Fugue
38.17
19%
25
- C1 -
-
5JSD
13
?
A:
[172-719]
QTQ
Y
Y
L
K
Y
F
N
P
E
I
V
Y
P
K
N
A
----
R
I
M
L
D
N
G
D
I
V
R
S
TVVNNTSNPNVDMTGW
V
K
V
S
-
S
V
S
Q
I
F
D
E
T
Y
--
N
I
T
Q
S
V
I
N
G
N
L
I
T
V
D
N
FGAKGDGV
T
D
D
S
A
A
F
--
Q
A
Y
-
C
D
S
A
---
L
T
G
Q
N
L
Y
L
G
A
-
K
G
R
Y
I
L
KNQV
D
L
K
G
K
G
L
V
G
N
G
C
G
K
-
V
S
E
F
Y
Y
N
L
G
C
I
D
V
DGS
S
P
D
L
Q
G
K
T
A
F
I
N
CGPTI
Q
N
L
T
A
R
C
S
N
G
A
---
G
K
Q
V
--
S
F
I
---
E
----
I
-
D
G
Y
L
A
N
I
D
H
--
I
T
L
I
N
F
Y
N
Q
---
I
V
V
K
Q
A
--------
L
V
G
F
N
F
T
N
-
A
W
L
Y
YSQ
N
A
G
I
Y
C
--
E
D
P
L
N
----
R
V
-----
S
T
T
G
T
F
H
N
--
I
Y
F
Q
L
G
D
----
G
H
A
M
I
F
D
R
D
V
H
G
C
D
F
D
N
----
I
I
F
E
S
M
NGGIKARTVAH
C
G
F
G
K
F
W
C
E
N
LKTA
T
S
K
D
W
L
E
V
T
G
A
N
S
C
Y
G
N
S
F
T
G
Y
V
-------
K
L
L
G
G
W
T
S
KTS
P
T
L
D
S
L
P
--
T
NNY
G
G
V
S
V
S
A
E
G
I
S
I
V
N
A
-
G
N
K
A
K
M
L
M
L
P
-
S
G
F
K
T
-----
G
NA
T
I
D
E
T
H
ISSS
T
V
T
P
L
V
K
R
R
V
-
I
GADSSG
A
Q
Y
L
A
S
D
T
Y
T
K
L
S
R
K
W
G
T
Y
N
H
G
S
N
N
A
G
A
F
Y
A
P
M
M
L
T
Y
D
Q
S
---
F
S
-----
T
P
Q
N
N
N
G
W
K
-
I
V
K
E
S
T
------
G
V
Y
R
V
E
R
V
S
G
N
----
T
S
V
I
T
N
G
H
---
I
-
V
V
-
G
S
P
L
M
G
S
R
L
G
T
G
T
G
A
----------
T
H
G
I
Q
-
M
I
E
T
Y
A
G
S
W
T
S
-
Y
T
E
A
A
G
F
K
V
F
W
----
R
D
-
S
S
N
A
L
V
D
P
H
R
F
T
V
A
F
T
AT
S
-------------------------------------------------------------------------
18
HHSearch
35.71
9%
-69
- C5 -
-
5KIZ
-
A:
[2-113]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
F
L
D
S
K
T
F
L
S
R
F
S
M
---
D
M
-----
K
F
T
Y
C
D
D
R
I
---
T
E
L
I
------
G
Y
H
P
E
E
L
L
G
R
S
----
A
S
E
F
W
H
A
L
D
-
S
E
-
N
M
T
K
S
H
Q
N
L
C
T
K
G
Q
V
V
S
G
Q
Y
R
--
M
L
A
K
H
G
G
Y
V
W
-
L
E
T
Q
M
T
V
I
Y
N
P
R
N
L
Q
P
Q
C
I
M
A
V
N
----
Y
V
L
S
E
I
E
----------------------------------------------------------------------------------------
4
HHSearch
34.92
16%
13
- C4 -
-
3U9M
-
FBXL5_HUMAN
C:
[4-154]
-----------------------------------------------------------------------------------------------------------------------------------------
F
P
E
-
E
V
D
V
F
T
-
A
P
H
W
R
M
K
Q
L
V
G
L
Y
---
C
D
K
L
S
K
T
N
F
S
N
N
----------
N
D
F
R
A
L
---
L
Q
S
L
--
Y
A
T
-
F
K
E
----
F
-
K
M
H
E
Q
I
E
N
E
Y
I
I
G
L
L
Q
Q
R
S
Q
----
T
I
Y
-
N
--------
V
H
S
D
-
N
K
L
-
S
E
M
L
---
S
L
F
E
K
G
--
L
K
N
V
K
----
N
E
YEQLN
Y
A
K
Q
L
K
E
R
--
L
E
A
F
T
R
D
----
F
L
P
H
M
K
E
---
E
E
E
V
F
Q
P
----
M
L
M
E
Y
F
-------------------------
T
Y
E
E
L
K
D
I
K
K
K
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
HHSearch
34.26
15%
48
- C5 -
-
2Z6D
1
PHOT2_ARATH
A:
[7-124]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
L
K
T
A
L
S
T
L
Q
Q
T
F
V
V
S
D
A
TQP
H
C
-----
P
I
V
Y
A
S
S
G
F
---
F
T
M
T
------
G
Y
S
S
K
E
I
V
G
R
N
----
C
R
F
L
Q
G
P
D
T
-
D
K
N
E
V
-
A
K
I
R
D
C
V
K
N
G
K
S
Y
C
G
R
L
L
--
N
Y
K
K
D
G
T
P
F
W
-
N
L
L
T
V
T
P
I
K
D
D
-
Q
G
N
T
I
K
F
I
G
M
Q
----
V
E
V
S
K
Y
T
----------------------------------------------------------------------------------------
11
HHSearch
33.62
11%
26
- C5 -
-
5DKK
1
?
B:
[7-129]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
F
I
K
A
L
Q
T
A
Q
Q
N
F
V
V
T
D
P
SLP
D
N
-----
P
I
V
Y
A
S
Q
G
F
---
L
N
L
T
------
G
Y
S
L
D
Q
I
L
G
R
N
----
C
R
F
L
Q
G
P
E
T
-
D
P
K
A
V
-
E
R
I
R
K
A
I
E
Q
G
N
D
M
S
V
C
L
L
--
N
Y
R
V
D
G
T
T
F
W
-
N
Q
F
F
I
A
A
L
R
D
A
-
G
G
N
V
T
N
F
V
G
V
Q
----
C
K
V
S
D
Q
Y
A
A
T
V
T
-----------------------------------------------------------------------------------