@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : spr0622: (2017-12-25 )
MSETILEIKELKKSFGDNPILQGLSLEIKKGEVVVILGPSGCGKSTLLRCLNGLESIQGGDILLDGQSIVENKKDFHLVRQKIGMVFQSYELFPHLDVLQNLILGPIKAQGRDKKEVTEEALQLLERVGLLDKQHSFARQLSGGQKQRVAIVRALLMHPEIILFDEVTASLDPEMVREVLELINDLAQEGRTMILVTHEMQFAQAIADQIIFLDQGKIAEEGTAQAFFTNPQTKRAQEFLNVFDFSQFGSYL
Atome Classification :
(35 SA)
.........10........---20........30........40........50...----.....60.....-------------...-----------70-....----....80........90........100......--.110.......120.......130.-....--..----140-------------.........150.....-..160.......170..---.....180......-..-190........200.......210...-....220.......230.......-----240.......250
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MS
E
T
I
L
E
I
K
E
L
K
K
SFGDN
P
---
I
LQG
L
S
L
E
I
KKG
E
V
V
V
I
LGPSGC
G
K
S
T
L
L
R
C
L
N
G
L
----
E
SIQGG
D
I
L
LD
G
-------------
Q
S
I
-----------VE-N
K
K
D
----
F
H
L
V
R
Q
K
I
G
M
V
F
Q
S
Y
ELFP
H
L
D
V
L
Q
N
LILGPIK--AQGR
D
K
K
E
V
T
E
E
A
L
Q
L
L
E
RVGLL
D
K
-
Q
H
S
F
--
A
R
----
Q
---------------LSGG
Q
K
Q
R
V
A
I
V
R
A
L
LM-HP
E
I
I
L
F
D
E
V
TASL
D
P
E
---
M
V
R
E
V
L
E
-
L
I
N
D
L
A
-QE-G
R
-
T
M
I
L
V
T
H
E
M
Q
F
A
Q
A
I
A
D
Q
I
I
F
LDQ-GKIAEEGTA
Q
A
F
FTNP
Q
T
K
R
A
Q
E
F
-----
L
N
V
F
D
F
S
Q
FGSYL
22
PsiBlast_CBE
91.35
52%
-136
- C1 -
-
4YMU
1
?
A:
[4-237]
-------
V
N
D
V
Y
K
N
F
G
S
L
E
---
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
----
E
E
P
T
K
G
E
V
F
I
D
G
-------------
V
K
I
-----------
N
N
-
G
K
V
N
----
I
N
K
V
R
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
L
A
P
V
K
--
V
K
K
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
K
-
K
D
Q
Y
--
P
I
----
K
---------------
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
-
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
---
M
V
K
E
V
L
N
-
V
M
K
Q
L
A
-
N
E
-
G
M
-
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
-
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
E
R
T
R
E
F
-----
L
S
-----------
21
PsiBlast_CBE
91.01
52%
-133
- C1 -
-
4YMV
1
?
A:
[4-237]
-------
V
N
D
V
Y
K
N
F
G
S
L
E
---
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
----
E
E
P
T
K
G
E
V
F
I
D
G
-------------
V
K
I
-----------
N
N
-
G
K
V
N
----
I
N
K
V
R
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
L
A
P
V
K
--
V
K
K
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
K
-
K
D
Q
Y
--
P
I
----
K
---------------
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
-
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
---
M
V
K
E
V
L
N
-
V
M
K
Q
L
A
-
N
E
-
G
M
-
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
-
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
E
R
T
R
E
F
-----
L
S
-----------
2
PsiBlast_PDB
90.81
52%
-131
- C1 -
-
4YMT
-
?
J:
[4-237]
-------
V
N
D
V
Y
K
N
F
G
S
L
E
---
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
----
E
E
P
T
K
G
E
V
F
I
D
G
-------------
V
K
I
-----------
N
N
-
G
K
V
N
----
I
N
K
V
R
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
L
A
P
V
K
--
V
K
K
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
K
-
K
D
Q
Y
--
P
I
----
K
---------------
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
-
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
---
M
V
K
E
V
L
N
-
V
M
K
Q
L
A
-
N
E
-
G
M
-
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
-
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
E
R
T
R
E
F
-----
L
S
-----------
4
PsiBlast_PDB
90.56
52%
-134
- C1 -
-
4YMV
1
?
J:
[4-237]
-------
V
N
D
V
Y
K
N
F
G
S
L
E
---
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
----
E
E
P
T
K
G
E
V
F
I
D
G
-------------
V
K
I
-----------
N
N
-
G
K
V
N
----
I
N
K
V
R
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
L
A
P
V
K
--
V
K
K
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
K
-
K
D
Q
Y
--
P
I
----
K
---------------
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
-
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
---
M
V
K
E
V
L
N
-
V
M
K
Q
L
A
-
N
E
-
G
M
-
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
-
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
E
R
T
R
E
F
-----
L
S
-----------
5
PsiBlast_PDB
90.35
52%
-134
- C1 -
-
4YMW
-
?
J:
[4-237]
-------
V
N
D
V
Y
K
N
F
G
S
L
E
---
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
----
E
E
P
T
K
G
E
V
F
I
D
G
-------------
V
K
I
-----------
N
N
-
G
K
V
N
----
I
N
K
V
R
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
L
A
P
V
K
--
V
K
K
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
K
-
K
D
Q
Y
--
P
I
----
K
---------------
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
-
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
---
M
V
K
E
V
L
N
-
V
M
K
Q
L
A
-
N
E
-
G
M
-
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
-
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
E
R
T
R
E
F
-----
L
S
-----------
33
PsiBlast_CBE
90.19
48%
-135
- C1 -
-
2OLK
2
?
B:
[24-260]
----
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
E
---
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
----
E
D
F
D
E
G
E
I
I
I
D
G
-------------
I
N
L
-----------
K
A
-
K
D
T
N
----
L
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
--
V
R
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
K
-
A
H
A
Y
--
P
D
----
S
---------------
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
---
M
V
G
E
V
L
S
-
V
M
K
Q
L
A
-
N
E
-
G
M
-
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
-
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
-----
L
S
-----------
6
PsiBlast_PDB
90.16
50%
-126
- C1 -
-
4U00
1
?
A:
[3-238]
---
P
I
I
R
I
R
N
L
H
K
W
F
G
P
L
H
---
V
L
K
G
I
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
R
L
----
E
D
F
Q
E
G
E
V
V
V
D
G
-------------
L
S
------------
V
K
-
D
D
R
A
----
L
R
E
I
R
R
E
V
G
M
V
F
Q
Q
F
N
L
F
P
H
M
T
V
L
E
N
V
T
L
A
P
M
R
--
V
R
R
W
P
R
E
K
A
E
K
K
A
L
E
L
L
E
R
V
G
I
L
D
Q
-
A
R
K
Y
--
P
A
----
Q
---------------
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
---
M
V
G
E
V
L
D
-
V
M
R
D
L
A
-
Q
G
-
G
M
-
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
A
D
R
V
V
F
M
D
G
-
G
Q
I
V
E
E
G
R
P
E
E
I
F
T
R
P
K
E
E
R
T
R
S
F
-----
L
------------
1
PsiBlast_PDB
90.12
52%
-133
- C1 -
-
4YMS
-
?
J:
[4-237]
-------
V
N
D
V
Y
K
N
F
G
S
L
E
---
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
----
E
E
P
T
K
G
E
V
F
I
D
G
-------------
V
K
I
-----------
N
N
-
G
K
V
N
----
I
N
K
V
R
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
L
A
P
V
K
--
V
K
K
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
K
-
K
D
Q
Y
--
P
I
----
K
---------------
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
-
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
---
M
V
K
E
V
L
N
-
V
M
K
Q
L
A
-
N
E
-
G
M
-
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
-
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
E
R
T
R
E
F
-----
L
S
-----------
31
PsiBlast_CBE
89.62
48%
-136
- C1 -
-
2OLK
1
?
D:
[24-260]
----
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
E
---
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
----
E
D
F
D
E
G
E
I
I
I
D
G
-------------
I
N
L
-----------
K
A
-
K
D
T
N
----
L
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
--
V
R
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
K
-
A
H
A
Y
--
P
D
----
S
---------------
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
---
M
V
G
E
V
L
S
-
V
M
K
Q
L
A
-
N
E
-
G
M
-
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
-
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
-----
L
S
-----------
3
PsiBlast_PDB
89.36
52%
-133
- C1 -
-
4YMU
1
?
J:
[4-237]
-------
V
N
D
V
Y
K
N
F
G
S
L
E
---
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
----
E
E
P
T
K
G
E
V
F
I
D
G
-------------
V
K
I
-----------
N
N
-
G
K
V
N
----
I
N
K
V
R
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
L
A
P
V
K
--
V
K
K
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
K
-
K
D
Q
Y
--
P
I
----
K
---------------
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
-
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
---
M
V
K
E
V
L
N
-
V
M
K
Q
L
A
-
N
E
-
G
M
-
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
-
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
E
R
T
R
E
F
-----
L
S
-----------
7
PsiBlast_PDB
89.11
50%
-120
- C1 -
-
4U02
-
?
A:
[2-238]
--
E
P
I
I
R
I
R
N
L
H
K
W
F
G
P
L
H
---
V
L
K
G
I
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
R
L
----
E
D
F
Q
E
G
E
V
V
V
D
G
-------------
L
S
------------
V
K
-
D
D
R
A
----
L
R
E
I
R
R
E
V
G
M
V
F
Q
Q
F
N
L
F
P
H
M
T
V
L
E
N
V
T
L
A
P
M
R
--
V
R
R
W
P
R
E
K
A
E
K
K
A
L
E
L
L
E
R
V
G
I
L
D
Q
-
A
R
K
Y
--
P
A
----
Q
---------------
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
---
M
V
G
E
V
L
D
-
V
M
R
D
L
A
-
Q
G
-
G
M
-
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
A
D
R
V
V
F
M
D
G
-
G
Q
I
V
E
E
G
R
P
E
E
I
F
T
R
P
K
E
E
R
T
R
S
F
-----
L
------------
26
PsiBlast_CBE
88.44
48%
-138
- C1 -
-
3C4J
2
?
B:
[24-260]
----
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
E
---
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
----
E
D
F
D
E
G
E
I
I
I
D
G
-------------
I
N
L
-----------
K
A
-
K
D
T
N
----
L
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
--
V
R
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
K
-
A
H
A
Y
--
P
D
----
S
---------------
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
---
M
V
G
E
V
L
S
-
V
M
K
Q
L
A
-
N
E
-
G
M
-
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
-
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
-----
L
S
-----------
8
PsiBlast_PDB
88.18
48%
-142
- C1 -
-
2OLJ
3
?
A:
[24-260]
----
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
E
---
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
----
E
D
F
D
E
G
E
I
I
I
D
G
-------------
I
N
L
-----------
K
A
-
K
D
T
N
----
L
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
--
V
R
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
K
-
A
H
A
Y
--
P
D
----
S
---------------
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
---
M
V
G
E
V
L
S
-
V
M
K
Q
L
A
-
N
E
-
G
M
-
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
-
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
-----
L
S
-----------
9
PsiBlast_PDB
87.92
48%
-140
- C1 -
-
2OLK
1
?
A:
[24-260]
----
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
E
---
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
----
E
D
F
D
E
G
E
I
I
I
D
G
-------------
I
N
L
-----------
K
A
-
K
D
T
N
----
L
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
--
V
R
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
K
-
A
H
A
Y
--
P
D
----
S
---------------
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
---
M
V
G
E
V
L
S
-
V
M
K
Q
L
A
-
N
E
-
G
M
-
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
-
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
-----
L
S
-----------
13
PsiBlast_PDB
87.60
48%
-127
- C1 -
-
3C41
2
?
J:
[3-239]
----
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
E
---
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
----
E
D
F
D
E
G
E
I
I
I
D
G
-------------
I
N
L
-----------
K
A
-
K
D
T
N
----
L
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
--
V
R
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
K
-
A
H
A
Y
--
P
D
----
S
---------------
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
---
M
V
G
E
V
L
S
-
V
M
K
Q
L
A
-
N
E
-
G
M
-
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
-
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
-----
L
S
-----------
27
PsiBlast_CBE
87.52
48%
-144
- C1 -
-
2Q0H
3
?
B:
[24-260]
----
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
E
---
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
----
E
D
F
D
E
G
E
I
I
I
D
G
-------------
I
N
L
-----------
K
A
-
K
D
T
N
----
L
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
--
V
R
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
K
-
A
H
A
Y
--
P
D
----
S
---------------
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
---
M
V
G
E
V
L
S
-
V
M
K
Q
L
A
-
N
E
-
G
M
-
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
-
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
-----
L
S
-----------
12
PsiBlast_PDB
87.12
48%
-134
- C1 -
-
3C4J
2
?
A:
[24-260]
----
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
E
---
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
----
E
D
F
D
E
G
E
I
I
I
D
G
-------------
I
N
L
-----------
K
A
-
K
D
T
N
----
L
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
--
V
R
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
K
-
A
H
A
Y
--
P
D
----
S
---------------
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
---
M
V
G
E
V
L
S
-
V
M
K
Q
L
A
-
N
E
-
G
M
-
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
-
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
-----
L
S
-----------
10
PsiBlast_PDB
86.62
48%
-143
- C1 -
-
2OUK
-
?
A:
[24-260]
----
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
E
---
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
----
E
D
F
D
E
G
E
I
I
I
D
G
-------------
I
N
L
-----------
K
A
-
K
D
T
N
----
L
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
--
V
R
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
K
-
A
H
A
Y
--
P
D
----
S
---------------
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
---
M
V
G
E
V
L
S
-
V
M
K
Q
L
A
-
N
E
-
G
M
-
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
-
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
-----
L
S
-----------
11
PsiBlast_PDB
85.60
48%
-135
- C1 -
-
2Q0H
3
?
A:
[24-260]
----
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
E
---
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
----
E
D
F
D
E
G
E
I
I
I
D
G
-------------
I
N
L
-----------
K
A
-
K
D
T
N
----
L
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
--
V
R
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
K
-
A
H
A
Y
--
P
D
----
S
---------------
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
---
M
V
G
E
V
L
S
-
V
M
K
Q
L
A
-
N
E
-
G
M
-
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
-
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
-----
L
S
-----------
32
PsiBlast_CBE
85.53
48%
-138
- C1 -
-
2OLK
1
?
C:
[24-260]
----
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
E
---
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
----
E
D
F
D
E
G
E
I
I
I
D
G
-------------
I
N
L
-----------
K
A
-
K
D
T
N
----
L
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
--
V
R
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
K
-
A
H
A
Y
--
P
D
----
S
---------------
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
---
M
V
G
E
V
L
S
-
V
M
K
Q
L
A
-
N
E
-
G
M
-
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
-
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
-----
L
S
-----------
34
PsiBlast_CBE
84.96
48%
-132
- C1 -
-
2OLJ
2
?
B:
[24-260]
----
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
E
---
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
----
E
D
F
D
E
G
E
I
I
I
D
G
-------------
I
N
L
-----------
K
A
-
K
D
T
N
----
L
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
--
V
R
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
K
-
A
H
A
Y
--
P
D
----
S
---------------
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
---
M
V
G
E
V
L
S
-
V
M
K
Q
L
A
-
N
E
-
G
M
-
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
-
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
-----
L
S
-----------
35
PsiBlast_CBE
84.31
48%
-137
- C1 -
-
3C41
2
?
K:
[3-239]
----
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
E
---
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
----
E
D
F
D
E
G
E
I
I
I
D
G
-------------
I
N
L
-----------
K
A
-
K
D
T
N
----
L
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
--
V
R
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
K
-
A
H
A
Y
--
P
D
----
S
---------------
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
---
M
V
G
E
V
L
S
-
V
M
K
Q
L
A
-
N
E
-
G
M
-
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
-
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
-----
L
S
-----------
14
PsiBlast_PDB
79.70
45%
-22
- C1 -
-
1B0U
1
HISP_SALTY
A:
[5-253]
---
N
K
L
H
V
I
D
L
H
K
R
Y
G
G
H
E
---
V
L
K
G
V
S
L
Q
A
R
A
G
D
V
I
S
I
I
G
S
S
G
S
G
K
S
T
F
L
R
C
I
N
F
L
----
E
K
P
S
E
G
A
I
I
V
N
G
-------------
Q
N
I
N
L
V
R
D
KDGQLK
V
A
-
D
K
N
Q
----
L
R
L
L
R
T
R
L
T
M
V
F
Q
H
F
N
L
W
S
H
M
T
V
L
E
N
V
M
E
A
P
I
Q
--
V
L
G
L
S
K
H
D
A
R
E
R
A
L
K
Y
L
A
K
V
G
I
D
E
R
A
Q
G
K
Y
--
P
V
----
H
---------------
L
S
G
G
Q
Q
Q
R
V
S
I
A
R
A
L
A
M
-
E
P
D
V
L
L
F
D
E
P
T
S
A
L
D
P
E
---
L
V
G
E
V
L
R
-
I
M
Q
Q
L
A
-
E
E
-
G
K
-
T
M
V
V
V
T
H
E
M
G
F
A
R
H
V
S
S
H
V
I
F
L
H
Q
-
G
K
I
E
E
E
G
D
P
E
Q
V
F
G
N
P
Q
S
P
R
L
Q
Q
F
-----
L
------------
73
PsiBlast_CBE
68.40
35%
-120
- C1 -
-
3FVQ
2
FBPC_NEIG1
B:
[5-239]
-----
L
H
I
G
H
L
S
K
S
F
Q
N
T
P
---
V
L
N
D
I
S
L
S
L
D
P
G
E
I
L
F
I
I
G
A
S
G
C
G
K
T
T
L
L
R
C
L
A
G
F
----
E
Q
P
D
S
G
E
I
S
L
S
G
-------------
K
T
I
-----------
F
S
-
K
N
T
N
----
L
P
V
R
E
R
R
L
G
Y
L
V
Q
E
G
V
L
F
P
H
L
T
V
Y
R
N
I
A
Y
G
L
G
N
--
G
K
G
R
T
A
Q
E
-
R
Q
R
I
E
A
M
L
E
L
T
G
I
S
E
L
-
A
G
R
Y
--
P
H
----
E
---------------
L
S
G
G
Q
Q
Q
R
A
A
L
A
R
A
L
A
P
-
D
P
E
L
I
L
L
D
E
P
F
S
A
L
D
E
Q
---
L
R
R
Q
I
R
E
D
M
I
A
A
L
R
-
A
N
-
G
K
-
S
A
V
F
V
S
H
D
R
E
E
A
L
Q
Y
A
D
R
I
A
V
M
K
Q
-
G
R
I
L
Q
T
A
S
P
H
E
L
Y
R
Q
P
A
D
L
D
A
A
L
F
-----
I
------------
74
PsiBlast_CBE
65.12
35%
-122
- C1 -
-
3FVQ
2
FBPC_NEIG1
A:
[5-244]
-----
L
H
I
G
H
L
S
K
S
F
Q
N
T
P
---
V
L
N
D
I
S
L
S
L
D
P
G
E
I
L
F
I
I
G
A
S
G
C
G
K
T
T
L
L
R
C
L
A
G
F
----
E
Q
P
D
S
G
E
I
S
L
S
G
-------------
K
T
I
-----------
F
S
-
K
N
T
N
----
L
P
V
R
E
R
R
L
G
Y
L
V
Q
E
G
V
L
F
P
H
L
T
V
Y
R
N
I
A
Y
G
L
G
N
--
G
K
G
R
T
A
Q
E
-
R
Q
R
I
E
A
M
L
E
L
T
G
I
S
E
L
-
A
G
R
Y
--
P
H
----
E
---------------
L
S
G
G
Q
Q
Q
R
A
A
L
A
R
A
L
A
P
-
D
P
E
L
I
L
L
D
E
P
F
S
A
L
D
E
Q
---
L
R
R
Q
I
R
E
D
M
I
A
A
L
R
-
A
N
-
G
K
-
S
A
V
F
V
S
H
D
R
E
E
A
L
Q
Y
A
D
R
I
A
V
M
K
Q
-
G
R
I
L
Q
T
A
S
P
H
E
L
Y
R
Q
P
A
D
L
D
A
A
L
F
-----
I
------------
160
HHSearch
61.91
34%
-127
- C1 -
-
3FVQ
2
FBPC_NEIG1
B:
[3-230]
---
A
A
L
H
I
G
H
L
S
K
S
F
Q
N
T
P
---
V
L
N
D
I
S
L
S
L
D
P
G
E
I
L
F
I
I
G
A
S
G
C
G
K
T
T
L
L
R
C
L
A
G
F
----
E
Q
P
D
S
G
E
I
S
L
S
G
-------------
K
T
I
-----------
F
S
-
K
N
T
N
----
L
P
V
R
E
R
R
L
G
Y
L
V
Q
E
G
V
L
F
P
H
L
T
V
Y
R
N
I
A
Y
G
L
G
N
--
G
K
G
-
R
T
A
Q
E
R
Q
R
I
E
A
M
L
E
L
T
G
I
S
E
L
-
A
G
R
Y
--
P
H
----
E
---------------
L
S
G
G
Q
Q
Q
R
A
A
L
A
R
A
L
A
P
-
D
P
E
L
I
L
L
D
E
P
F
S
A
L
D
E
Q
---
L
R
R
Q
I
R
E
-
D
M
I
A
A
L
R
A
N
-
G
K
-
S
A
V
F
V
S
H
D
R
E
E
A
L
Q
Y
A
D
R
I
A
V
M
K
Q
-
G
R
I
L
Q
T
A
S
P
H
E
L
Y
R
Q
P
--------------------------
157
Fugue
58.41
41%
35
- C1 -
-
1B0U
1
HISP_SALTY
A:
[5-261]
---
N
K
L
H
V
I
D
L
H
K
R
Y
G
G
--HEV
L
K
-
G
V
S
L
Q
A
R
A
G
D
V
I
S
I
I
G
S
S
G
S
G
K
S
T
F
L
R
C
I
N
F
L
EKPS----
E
G
A
I
I
V
N
G
QNI
N
L
V
R
D
KDGQL
K
V
A
-----------
D
K
-
N
Q
L
R
----
L
L
R
T
-
R
-
L
T
M
V
F
Q
H
F
N
L
W
S
H
M
T
V
L
E
N
V
M
E
A
P
I
Q
VL--
G
L
S
K
H
D
A
R
E
R
A
L
K
Y
L
A
K
V
G
I
D
E
R
-
A
Q
G
-KY
P
V
----
H
---------------
L
S
G
G
Q
Q
Q
R
V
S
I
A
R
A
L
A
M
E-
P
D
V
L
L
F
D
E
P
T
S
A
L
D
P
E
---
L
V
G
E
V
L
R
-
I
M
Q
Q
L
A
-
E
E
-
G
K
-
T
M
V
V
V
T
H
E
M
G
F
A
R
H
V
S
S
H
V
I
F
L
H
-Q
G
K
I
E
E
E
G
D
P
E
Q
V
F
G
N
P
-
Q
S
P
R
L
Q
Q
-----
F
L
K
G
S
L
K
K
L
E
---
77
PsiBlast_CBE
58.22
32%
-48
- C1 -
-
1VCI
1
?
A:
[13-266]
-----
V
K
L
E
N
L
T
K
R
F
G
N
F
T
---
A
V
N
K
L
N
L
T
I
K
D
G
E
F
L
V
L
L
G
P
S
G
C
G
K
T
T
T
L
R
M
I
A
G
L
----
E
E
P
T
E
G
R
I
Y
F
G
D
-------------
R
D
V
-----------
T
Y
L
P
P
K
D
---------
R
N
I
S
M
V
F
Q
------
H
M
T
V
Y
E
N
I
A
F
-
P
L
----
K
K
F
P
K
D
E
I
D
K
R
V
R
W
A
A
E
L
L
Q
I
E
E
L
-
L
N
R
Y
--
P
A
----
Q
---------------
L
S
G
G
Q
R
Q
R
V
A
V
A
R
A
I
V
V
-
E
P
D
V
L
L
M
D
E
P
L
S
N
L
D
A
K
---
L
R
V
A
M
R
A
-
E
I
K
K
L
Q
-
Q
K
-
L
K
V
T
T
I
Y
V
T
H
D
Q
V
E
A
M
T
M
G
D
R
I
A
V
M
N
R
-
G
Q
L
L
Q
I
G
S
P
T
E
V
Y
L
R
P
N
S
V
F
V
A
T
F
I
GAPE
M
N
I
L
E
V
S
V
G
D
G
Y
L
107
PsiBlast_CBE
51.72
37%
-29
- C1 -
-
1L2T
3
Y796_METJA
B:
[21-232]
-----------------------
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
----
D
K
P
T
E
G
E
V
Y
I
D
---------------
N
I
-----------
K
T
-
N
D
L
D
DDEL
T
K
I
R
R
D
K
I
G
F
V
F
Q
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
E
L
-
P
L
I
--
F
K
Y
R
G
A
M
S
G
E
E
R
R
K
R
A
L
E
C
L
K
M
A
E
L
-
E
E
R
F
--
A
N
HKPN
Q
---------------
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
-
N
P
P
I
I
L
A
D
Q
P
T
G
A
L
D
S
K
---
T
G
E
K
I
M
Q
-
L
L
K
K
L
N
-
E
E
D
G
K
-
T
V
V
V
V
T
H
D
I
N
V
A
R
-
F
G
E
R
I
I
Y
L
K
D
-
G
E
V
E
R
E
E
K
L
R
G
F
------------------------------
108
PsiBlast_CBE
49.79
37%
-23
- C1 -
-
1L2T
3
Y796_METJA
A:
[21-230]
-----------------------
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
----
D
K
P
T
E
G
E
V
Y
I
D
---------------
N
I
-----------
K
T
-
N
D
L
D
D
D
E
L
T
K
I
R
R
D
K
I
G
F
V
F
Q
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
E
L
-
P
L
I
--
F
K
Y
R
G
A
M
S
G
E
E
R
R
K
R
A
L
E
C
L
K
M
A
E
L
-
E
E
R
F
--
A
N
HKPN
Q
---------------
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
-
N
P
P
I
I
L
A
D
Q
P
T
G
A
L
D
S
K
---
T
G
E
K
I
M
Q
-
L
L
K
K
L
N
-
E
E
D
G
K
-
T
V
V
V
V
T
H
D
I
N
V
A
R
-
F
G
E
R
I
I
Y
L
K
D
-
G
E
V
E
R
E
E
K
L
R
--------------------------------
111
PsiBlast_CBE
48.13
35%
-13
- C1 -
-
3TIF
4
Y796_METJA
A:
[21-230]
-----------------------
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
----
D
K
P
T
E
G
E
V
Y
I
D
N
IK-----------
T
N
D
-----------
L
D
-
D
D
E
L
----
T
K
I
R
R
D
K
I
G
F
V
F
Q
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
E
L
-
P
L
I
--
F
K
Y
R
G
A
M
S
G
E
E
R
R
K
R
A
L
E
C
L
K
M
A
E
L
-
E
E
R
F
--
A
N
HKPN
Q
---------------
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
-
N
P
P
I
I
L
A
D
Q
P
T
W
A
L
D
S
K
---
T
G
E
K
I
M
Q
-
L
L
K
K
L
N
-
E
E
D
G
K
-
T
V
V
V
V
T
H
D
I
N
V
A
R
-
F
G
E
R
I
I
Y
L
K
D
-
G
E
V
E
R
E
E
K
L
R
--------------------------------
116
PsiBlast_CBE
47.86
36%
-73
- C1 -
-
4AYX
1
ABCBA_HUMAN
A:
[358-573]
------------------
P
---
I
F
Q
D
F
S
L
S
I
P
S
G
S
V
T
A
L
V
G
P
S
G
S
G
K
S
T
V
L
S
L
L
L
R
L
----
Y
D
P
A
S
G
T
I
S
L
D
G
-------------
H
D
I
-----------
R
Q
-
L
N
P
V
----
W
--
L
R
S
K
I
G
T
V
S
Q
E
P
I
L
F
-
S
C
S
I
A
E
N
I
A
Y
G
-------
A
D
D
P
S
S
V
T
A
E
E
I
Q
---
R
V
A
E
V
A
N
-
A
V
A
F
--
I
R
----
N
FPQGFN
T
V
V
G
EK
G
V
L
L
S
G
G
Q
K
Q
R
I
A
I
A
R
A
L
L
K
-
N
P
K
I
L
L
L
D
E
A
T
S
A
L
D
A
E
N
E
Y
L
V
Q
E
A
L
D
-
R
L
M
D
------
G
R
-
T
V
L
V
I
A
H
R
L
S
T
I
K
N
-
A
N
M
V
A
V
L
D
Q
-
G
K
I
T
E
Y
G
K
H
E
E
L
L
S
K
P
N
-------------------------
115
PsiBlast_CBE
47.34
36%
-79
- C1 -
-
4AYW
1
ABCBA_HUMAN
A:
[389-598]
------------------
P
---
I
F
Q
D
F
S
L
S
I
P
S
G
S
V
T
A
L
V
G
P
S
G
S
G
K
S
T
V
L
S
L
L
L
R
L
----
Y
D
P
A
S
G
T
I
S
L
D
G
-------------
H
D
I
-----------
R
Q
-
L
N
P
V
----
W
--
L
R
S
K
I
G
T
V
S
Q
E
P
I
L
F
-
S
C
S
I
A
E
N
I
A
Y
G
-------
A
D
D
P
S
S
V
T
A
E
E
I
Q
---
R
V
A
E
V
A
N
-
A
V
A
F
--
I
R
----
N
FPQGFN
T
V
V
G
EKG
V
L
L
S
G
G
Q
K
Q
R
I
A
I
A
R
A
L
L
K
-
N
P
K
I
L
L
L
D
E
----
L
D
A
E
N
E
Y
L
V
Q
E
A
L
D
-
R
L
M
D
------
G
R
-
T
V
L
V
I
A
H
H
L
S
T
I
K
N
-
A
N
M
V
A
V
L
D
Q
-
G
K
I
T
E
Y
G
K
H
E
E
-------------------------------
110
PsiBlast_CBE
46.54
35%
-10
- C1 -
-
3TIF
3
Y796_METJA
B:
[21-232]
-----------------------
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
----
D
K
P
T
E
G
E
V
Y
I
D
N
IK-----------
T
N
D
-----------
L
D
-
D
D
E
L
----
T
K
I
R
R
D
K
I
G
F
V
F
Q
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
E
L
-
P
L
I
--
F
K
Y
R
G
A
M
S
G
E
E
R
R
K
R
A
L
E
C
L
K
M
A
E
L
-
E
E
R
F
--
A
N
HKPN
Q
---------------
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
-
N
P
P
I
I
L
A
D
Q
P
T
W
A
L
D
S
K
---
T
G
E
K
I
M
Q
-
L
L
K
K
L
N
-
E
E
D
G
K
-
T
V
V
V
V
T
H
D
I
N
V
A
R
-
F
G
E
R
I
I
Y
L
K
D
-
G
E
V
E
R
E
E
K
L
R
G
F
------------------------------
117
PsiBlast_CBE
46.36
36%
-78
- C1 -
-
4AYT
1
ABCBA_HUMAN
A:
[358-567]
------------------
P
---
I
F
Q
D
F
S
L
S
I
P
S
G
S
V
T
A
L
V
G
P
S
G
S
G
K
S
T
V
L
S
L
L
L
R
L
----
Y
D
P
A
S
G
T
I
S
L
D
G
-------------
H
D
I
-----------
R
Q
-
L
N
P
V
----
W
--
L
R
S
K
I
G
T
V
S
Q
E
P
I
L
F
-
S
C
S
I
A
E
N
I
A
Y
G
-------
A
D
D
P
S
S
V
T
A
E
E
I
Q
---
R
V
A
E
V
A
N
-
A
V
A
F
--
I
R
----
N
FPQGFNTVVGEKG
V
L
L
S
G
G
Q
K
Q
R
I
A
I
A
R
A
L
L
K
-
N
P
K
I
L
L
L
D
E
A
T
S
A
L
D
A
E
N
E
Y
L
V
Q
E
A
L
D
-
R
L
M
D
------
G
R
-
T
V
L
V
I
A
H
R
L
S
T
I
K
N
-
A
N
M
V
A
V
L
D
Q
-
G
K
I
T
E
Y
G
K
H
E
E
-------------------------------