@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : spr0694: (2017-12-27 )
MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSGSGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLNALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALVNNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRDGVISSDSAQLGKEEN
Atome Classification :
(36 SA)
.........10........20........30........40........50........60........70.---------.......80........90........100.....-..-110.---......120.......130.....-..-140.......150.......160.......170.......180.......190.-......200-.-....-.-.210.......220.......230.-----------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
M
K
Q
L
I
S
L
K
N
I
F
R
S
YRNG
D
Q
E
L
Q
V
L
K
NIN
L
E
VNEG
E
F
V
A
I
MGPSGSG
K
S
T
L
M
N
T
IGMLDTPTSG
E
Y
Y
L
EG
Q
E
V---------AGL
G
E
K
Q
L
A
K
V
R
NQ
Q
I
G
F
V
F
Q
Q
F
F
L
L
S
K
L
N
A
L
QNV-EL-
P
L
I
Y
---AGV
S
S
S
K
R
R
K
L
A
E
E
Y
L
D
K
V
E
L
T
E
R
-SH-HL
P
S
ELSGG
Q
K
Q
R
V
A
I
A
R
A
L
VNNP
S
I
I
L
ADEPTGALDTK
T
G
N
Q
I
M
Q
L
L
V
DLNKE-G
K
T
I
I
M
V
TH-E-P
E
I
A
-
A
-
Y
A
K
R
Q
I
V
I
RDGVISS
D
S
A
QLGKEEN-----------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
85.62
52%
0
- C- -
-
5NIL
-
?
J:
[1-240]
M
T
P
L
L
E
L
K
D
I
R
R
S
Y
P
A
G
D
E
Q
V
E
V
L
K
G
I
S
L
D
I
Y
A
G
E
M
V
A
I
V
G
A
S
G
S
G
K
S
T
L
M
N
I
L
G
C
L
D
K
A
T
S
G
T
Y
R
V
A
G
Q
D
V
---------
A
T
L
D
A
D
A
L
A
Q
L
R
R
E
H
F
G
F
I
F
Q
R
Y
H
L
L
S
H
L
T
A
E
Q
N
V
-
E
V
-
P
A
V
Y
---
A
G
L
E
R
K
Q
R
L
L
R
A
Q
E
L
L
Q
R
L
G
L
E
D
R
-
T
E
-
Y
Y
P
A
Q
L
S
G
G
Q
Q
Q
R
V
S
I
A
R
A
L
M
N
G
G
Q
V
I
L
A
D
E
P
T
G
A
L
D
S
H
S
G
E
E
V
M
A
I
L
H
Q
L
R
D
R
-
G
H
T
V
I
I
V
T
H
-
D
-
P
Q
V
A
-
A
-
Q
A
E
R
V
I
E
I
R
D
G
E
I
-----------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
85.62
52%
0
- C- -
-
5NIK
-
?
J:
[1-240]
M
T
P
L
L
E
L
K
D
I
R
R
S
Y
P
A
G
D
E
Q
V
E
V
L
K
G
I
S
L
D
I
Y
A
G
E
M
V
A
I
V
G
A
S
G
S
G
K
S
T
L
M
N
I
L
G
C
L
D
K
A
T
S
G
T
Y
R
V
A
G
Q
D
V
---------
A
T
L
D
A
D
A
L
A
Q
L
R
R
E
H
F
G
F
I
F
Q
R
Y
H
L
L
S
H
L
T
A
E
Q
N
V
-
E
V
-
P
A
V
Y
---
A
G
L
E
R
K
Q
R
L
L
R
A
Q
E
L
L
Q
R
L
G
L
E
D
R
-
T
E
-
Y
Y
P
A
Q
L
S
G
G
Q
Q
Q
R
V
S
I
A
R
A
L
M
N
G
G
Q
V
I
L
A
D
E
P
T
G
A
L
D
S
H
S
G
E
E
V
M
A
I
L
H
Q
L
R
D
R
-
G
H
T
V
I
I
V
T
H
-
D
-
P
Q
V
A
-
A
-
Q
A
E
R
V
I
E
I
R
D
G
E
I
-----------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
84.18
53%
-12
- C1 -
-
1L2T
3
Y796_METJA
B:
[1-231]
---
M
I
K
L
K
N
V
T
K
T
Y
K
M
G
E
E
I
I
Y
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
I
K
T
---------
N
D
L
D
D
D
E
L
T
K
I
R
R
D
K
I
G
F
V
F
Q
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
-
E
L
-
P
L
I
F
KYR
G
A
M
S
G
E
E
R
R
K
R
A
L
E
C
L
K
M
A
E
L
E
E
R
F
A
N
-
H
K
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
G
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
G
K
T
V
V
V
V
T
H
-
D
-
I
N
V
A
-
R
-
F
G
E
R
I
I
Y
L
K
D
G
E
V
E
R
E
E
K
L
R
G
---------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
83.92
53%
-9
- C1 -
-
1L2T
3
Y796_METJA
A:
[1-230]
---
M
I
K
L
K
N
V
T
K
T
Y
K
M
G
E
E
I
I
Y
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
I
K
T
---------
N
D
L
D
D
D
E
L
T
K
I
R
R
D
K
I
G
F
V
F
Q
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
-
E
L
-
P
L
I
F
KYR
G
A
M
S
G
E
E
R
R
K
R
A
L
E
C
L
K
M
A
E
L
E
E
R
F
A
N
-
H
K
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
G
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
G
K
T
V
V
V
V
T
H
-
D
-
I
N
V
A
-
R
-
F
G
E
R
I
I
Y
L
K
D
G
E
V
E
R
E
E
K
L
R
----------------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
83.87
52%
-12
- C1 -
-
3TIF
4
Y796_METJA
B:
[1-231]
---
M
V
K
L
K
N
V
T
K
T
Y
K
M
G
E
E
I
I
Y
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
I
K
T
---------
N
D
L
D
D
D
E
L
T
K
I
R
R
D
K
I
G
F
V
F
Q
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
-
E
L
-
P
L
I
F
KYR
G
A
M
S
G
E
E
R
R
K
R
A
L
E
C
L
K
M
A
E
L
E
E
R
F
A
N
-
H
K
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
W
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
G
K
T
V
V
V
V
T
H
-
D
-
I
N
V
A
-
R
-
F
G
E
R
I
I
Y
L
K
D
G
E
V
E
R
E
E
K
L
R
G
---------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
82.67
52%
-10
- C1 -
-
3TIF
4
Y796_METJA
A:
[1-230]
---
M
V
K
L
K
N
V
T
K
T
Y
K
M
G
E
E
I
I
Y
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
I
K
T
---------
N
D
L
D
D
D
E
L
T
K
I
R
R
D
K
I
G
F
V
F
Q
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
-
E
L
-
P
L
I
F
KYR
G
A
M
S
G
E
E
R
R
K
R
A
L
E
C
L
K
M
A
E
L
E
E
R
F
A
N
-
H
K
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
W
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
G
K
T
V
V
V
V
T
H
-
D
-
I
N
V
A
-
R
-
F
G
E
R
I
I
Y
L
K
D
G
E
V
E
R
E
E
K
L
R
----------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
79.72
53%
-8
- C1 -
-
1F3O
1
Y796_METJA
A:
[2-231]
----
I
K
L
K
N
V
T
K
T
Y
K
M
G
E
E
I
I
Y
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
I
K
T
---------
N
D
L
D
D
D
E
L
T
K
I
R
R
D
K
I
G
F
V
F
Q
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
-
E
L
-
P
L
I
F
K
YR
G
A
M
S
G
E
E
R
R
K
R
A
L
E
C
L
K
M
A
E
L
E
E
R
F
A
N
-
H
K
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
E
P
T
G
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
G
K
T
V
V
V
V
T
H
-
D
-
I
N
V
A
-
R
-
F
G
E
R
I
I
Y
L
K
D
G
E
V
E
R
E
E
K
L
R
G
---------------------------------------------------------------------------------------------------------------------------------
143
Fugue
77.40
38%
-112
- C1 -
-
3TUZ
1
METN_ECOLI
H:
[23-362]
--
H
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
---------
T
T
L
S
E
S
E
L
T
K
A
R
R
Q
-
I
G
M
I
F
Q
H
F
N
L
L
S
S
R
T
V
F
G
N
V
-
A
L
-
P
L
E
L
---
D
N
T
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
G
L
G
D
K
-
H
D
-
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
-
E
M
D
V
V
K
-
R
-
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
F
S
H
PKTPLAQKFIQSTLHLDIPEDYQERLQAEPFTDCVPMLRLEFTGQSVDAPLLSETARRFNVNNNIISAQMDYAGGVKFGIMLTEMHGTQQDTQAAIAWLQEHHVKVEV-----------------
166
HHSearch
76.95
39%
-112
- C1 -
-
3TUI
1
METN_ECOLI
C:
[23-251]
--
H
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
---------
T
T
L
S
E
S
E
L
T
K
A
R
-
R
Q
I
G
M
I
F
Q
H
F
N
L
L
S
S
R
T
V
F
G
N
V
-
A
L
-
P
L
E
L
---
D
N
T
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
G
L
G
D
K
-
H
D
-
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
-
E
-
M
D
V
V
-
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
--------------------------------------------------------------------------------------------------------------------------------
145
Fugue
75.86
37%
-100
- C1 -
-
1OXS
-
?
C:
[1-352]
-
M
V
R
I
I
V
K
N
V
S
K
V
F
K
K
G
K
--
V
V
A
L
D
N
V
N
I
N
I
E
N
G
E
R
F
G
I
L
G
P
S
G
A
G
K
T
T
F
M
R
I
I
A
G
L
D
V
P
S
T
G
E
L
Y
F
D
D
R
L
V
---------
A
S
N
G
K
L
I
V
-
P
P
E
D
R
K
I
G
M
V
F
Q
T
W
A
L
Y
P
N
L
T
A
F
E
N
I
-
A
F
-
P
L
T
N
---
M
K
M
S
K
E
E
I
R
K
R
V
E
E
V
A
K
I
L
D
I
H
H
V
-
L
N
-
H
F
P
R
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
D
P
S
L
L
L
L
D
E
P
F
S
N
L
D
A
R
M
R
D
S
A
R
A
L
V
K
E
V
Q
S
R
L
G
V
T
L
L
V
V
S
H
D
P
-
A
D
I
F
-
A
-
I
A
D
R
V
G
V
L
V
K
G
K
L
V
----
Q
V
G
K
P
E
D
LYDNPVSIQVASLIGEINELEGKVTNEGVVIGSLRFPVSVSSDRAIIGIRPEDVKLSKDVIKDDSWILVGKGKVKVIGYQGGLFRITITPLDSEEEIFTYSDHPIHSGEEVLVYVRKDKIKVFEK
158
HHSearch
75.21
40%
-117
- C1 -
-
3DHW
-
METN_ECOLI
C:
[1-228]
---
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
---------
T
T
L
S
E
S
E
L
T
K
A
R
-
R
Q
I
G
M
I
F
Q
H
F
N
L
L
S
S
R
T
V
F
G
N
V
-
A
L
-
P
L
E
L
---
D
N
T
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
G
L
G
D
K
-
H
D
-
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
E
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
-
E
-
M
D
V
V
-
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
--------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
74.10
42%
-134
- C1 -
-
3TUZ
1
METN_ECOLI
C:
[23-226]
--
H
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
---------
T
T
L
S
E
S
E
L
T
K
A
R
-
R
Q
I
G
M
I
F
Q
H
F
N
L
L
S
S
R
T
V
F
G
N
V
-
A
L
-
P
L
E
L
---
D
N
T
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
G
L
G
D
K
-
H
D
-
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
-
E
-
M
D
V
----------------------------------------------------------------------------------------------------------------------------------------------------------
27
PsiBlast_CBE
70.65
42%
-128
- C1 -
-
3TUI
1
METN_ECOLI
H:
[23-226]
--
H
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
---------
T
T
L
S
E
S
E
L
T
K
A
R
-
R
Q
I
G
M
I
F
Q
H
F
N
L
L
S
S
R
T
V
F
G
N
V
-
A
L
-
P
L
E
L
---
D
N
T
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
G
L
G
D
K
-
H
D
-
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
-
E
-
M
D
V
----------------------------------------------------------------------------------------------------------------------------------------------------------
167
HHSearch
70.06
35%
-107
- C1 -
-
1OXX
-
?
K:
[3-229]
---
R
I
I
V
K
N
V
S
K
V
F
K
K
G
--
K
V
V
A
L
D
N
V
N
I
N
I
E
N
G
E
R
F
G
I
L
G
P
S
G
A
G
K
T
T
F
M
R
I
I
A
G
L
D
V
P
S
T
G
E
L
Y
F
D
D
R
L
V
---------
A
S
N
G
K
L
I
V
P
-
P
E
D
R
K
I
G
M
V
F
Q
T
W
A
L
Y
P
N
L
T
A
F
E
N
I
-
A
F
-
P
L
T
N
---
M
K
M
S
K
E
E
I
R
K
R
V
E
E
V
A
K
I
L
D
I
H
H
V
-
L
N
-
H
F
P
R
E
L
S
G
A
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
D
P
S
L
L
L
L
D
E
P
F
S
N
L
D
A
R
M
R
D
S
A
R
A
L
V
K
E
V
Q
S
R
L
G
V
T
L
L
V
V
S
H
-
D
-
P
A
D
I
-
F
A
I
A
D
R
V
G
V
L
V
K
G
K
L
V
Q
V
G
K
P
E
D
L
Y
-------------------------------------------------------------------------------------------------------------------------------
24
PsiBlast_CBE
69.11
42%
-129
- C1 -
-
3TUZ
1
METN_ECOLI
H:
[23-226]
--
H
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
---------
T
T
L
S
E
S
E
L
T
K
A
R
-
R
Q
I
G
M
I
F
Q
H
F
N
L
L
S
S
R
T
V
F
G
N
V
-
A
L
-
P
L
E
L
---
D
N
T
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
G
L
G
D
K
-
H
D
-
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
-
E
-
M
D
V
----------------------------------------------------------------------------------------------------------------------------------------------------------
146
Fugue
68.60
31%
-91
- C1 -
-
1Z47
-
?
A:
[11-355]
G
S
M
T
I
E
F
V
G
V
E
K
I
Y
P
G
G
---
A
R
S
V
R
G
V
S
F
Q
I
R
E
G
E
M
V
G
L
L
G
P
S
G
S
G
K
T
T
I
L
R
L
I
A
G
L
E
R
P
T
K
G
D
V
W
I
G
G
K
R
V
---------
T
D
L
P
P
Q
K
------
R
N
V
G
L
V
F
Q
N
Y
A
L
F
Q
H
M
T
V
Y
D
N
V
-
S
F
-
G
L
R
E
---
K
R
V
P
K
D
E
M
D
A
R
V
R
E
L
L
R
F
M
R
L
E
S
Y
-
A
N
-
R
F
P
H
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
A
P
R
P
Q
V
L
L
F
D
E
P
F
A
A
I
D
T
Q
I
R
R
E
L
R
T
F
V
R
Q
V
H
D
E
M
G
V
T
S
V
F
V
T
H
D
Q
-
E
E
A
L
-
E
-
V
A
D
R
V
L
V
L
H
E
G
N
V
E
Q
F
G
T
P
E
E
V
Y
E
K
PGT
L
F
V
A
S
F
IGE
S
N
V
W
T
R
A
V
Q
NG
R
I
E
V
AG
A
A
L
P
V
DPAVSEG
S
E
V
A
V
V
V
R
PKD
V
E
L
Q
P
A
S
EREAHAQVV
R
S
A
F
KGS
Y
S
A
C
W
I
R
T
KD
G
E
V
W
E
V
H
V
P
SADRHRWSPG
A
W
V
H
M
N
V
T
R
W
F
I
F
P
R------
28
PsiBlast_CBE
68.29
42%
-124
- C1 -
-
3TUI
1
METN_ECOLI
G:
[24-226]
---
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
---------
T
T
L
S
E
S
E
L
T
K
A
R
-
R
Q
I
G
M
I
F
Q
H
F
N
L
L
S
S
R
T
V
F
G
N
V
-
A
L
-
P
L
E
L
---
D
N
T
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
G
L
G
D
K
-
H
D
-
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
-
E
-
M
D
V
----------------------------------------------------------------------------------------------------------------------------------------------------------
30
PsiBlast_CBE
67.55
40%
-78
- C1 -
-
4YMV
1
?
A:
[1-214]
---
M
I
F
V
N
D
V
Y
K
N
F
G
S
----
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
---------
N
N
-
G
K
V
N
I
N
K
V
R
-
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
-
T
L
A
P
V
K
V
---
K
K
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
K
-
K
D
-
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
-
E
-
M
G
F
A
R
E
-
V
G
D
R
V
I
F
M
D
D
G
V
I
-----------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
67.21
42%
-123
- C1 -
-
3TUI
1
METN_ECOLI
C:
[23-226]
--
H
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
---------
T
T
L
S
E
S
E
L
T
K
A
R
-
R
Q
I
G
M
I
F
Q
H
F
N
L
L
S
S
R
T
V
F
G
N
V
-
A
L
-
P
L
E
L
---
D
N
T
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
G
L
G
D
K
-
H
D
-
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
-
E
-
M
D
V
----------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
67.20
40%
-77
- C1 -
-
4YMV
1
?
J:
[1-214]
---
M
I
F
V
N
D
V
Y
K
N
F
G
S
----
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
---------
N
N
-
G
K
V
N
I
N
K
V
R
-
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
-
T
L
A
P
V
K
V
---
K
K
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
K
-
K
D
-
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
-
E
-
M
G
F
A
R
E
-
V
G
D
R
V
I
F
M
D
D
G
V
I
-----------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
66.89
40%
-73
- C1 -
-
4YMU
1
?
J:
[1-214]
---
M
I
F
V
N
D
V
Y
K
N
F
G
S
----
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
---------
N
N
-
G
K
V
N
I
N
K
V
R
-
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
-
T
L
A
P
V
K
V
---
K
K
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
K
-
K
D
-
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
-
E
-
M
G
F
A
R
E
-
V
G
D
R
V
I
F
M
D
D
G
V
I
-----------------------------------------------------------------------------------------------------------------------------------------
31
PsiBlast_CBE
64.43
40%
-76
- C1 -
-
4YMU
1
?
A:
[1-214]
---
M
I
F
V
N
D
V
Y
K
N
F
G
S
----
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
---------
N
N
-
G
K
V
N
I
N
K
V
R
-
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
-
T
L
A
P
V
K
V
---
K
K
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
K
-
K
D
-
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
-
E
-
M
G
F
A
R
E
-
V
G
D
R
V
I
F
M
D
D
G
V
I
-----------------------------------------------------------------------------------------------------------------------------------------
45
PsiBlast_CBE
61.26
39%
-73
- C1 -
-
2OLK
2
?
B:
[22-234]
-
L
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
----
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
---------
K
A
-
K
D
T
N
L
N
K
V
R
-
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
-
T
L
A
P
M
K
V
---
R
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
K
-
A
H
-
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
-
E
-
M
G
F
A
-
R
-
E
V
G
D
R
V
L
F
M
D
G
-------------------------------------------------------------------------------------------------------------------------------------------
44
PsiBlast_CBE
59.09
39%
-66
- C1 -
-
2OLK
1
?
C:
[22-234]
-
L
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
----
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
---------
K
A
-
K
D
T
N
L
N
K
V
R
-
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
-
T
L
A
P
M
K
V
---
R
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
K
-
A
H
-
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
-
E
-
M
G
F
A
-
R
-
E
V
G
D
R
V
L
F
M
D
G
-------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
58.59
40%
-65
- C1 -
-
4U00
1
?
A:
[3-213]
--
P
I
I
R
I
R
N
L
H
K
W
F
----
G
P
L
H
V
L
K
G
I
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
R
L
E
D
F
Q
E
G
E
V
V
V
D
G
L
S
V
---------
K
D
--
D
R
A
L
R
E
I
R
-
R
E
V
G
M
V
F
Q
Q
F
N
L
F
P
H
M
T
V
L
E
N
V
-
T
L
A
P
M
R
V
---
R
R
W
P
R
E
K
A
E
K
K
A
L
E
L
L
E
R
V
G
I
L
D
Q
-
A
R
-
K
Y
P
A
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
D
V
M
R
D
L
A
Q
G
-
G
M
T
M
V
V
V
T
H
-
E
-
M
G
F
A
-
R
-
E
V
A
D
R
V
V
F
M
D
G
-------------------------------------------------------------------------------------------------------------------------------------------
46
PsiBlast_CBE
57.61
39%
-59
- C1 -
-
2OLJ
2
?
B:
[22-234]
-
L
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
----
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
---------
K
A
-
K
D
T
N
L
N
K
V
R
-
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
-
T
L
A
P
M
K
V
---
R
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
K
-
A
H
-
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
-
E
-
M
G
F
A
-
R
-
E
V
G
D
R
V
L
F
M
D
G
-------------------------------------------------------------------------------------------------------------------------------------------
35
PsiBlast_CBE
57.61
39%
-63
- C1 -
-
3C4J
2
?
B:
[22-234]
-
L
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
----
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
---------
K
A
-
K
D
T
N
L
N
K
V
R
-
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
-
T
L
A
P
M
K
V
---
R
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
K
-
A
H
-
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
-
E
-
M
G
F
A
-
R
-
E
V
G
D
R
V
L
F
M
D
G
-------------------------------------------------------------------------------------------------------------------------------------------
43
PsiBlast_CBE
57.24
39%
-68
- C1 -
-
2OLK
1
?
D:
[22-234]
-
L
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
----
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
---------
K
A
-
K
D
T
N
L
N
K
V
R
-
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
-
T
L
A
P
M
K
V
---
R
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
K
-
A
H
-
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
-
E
-
M
G
F
A
-
R
-
E
V
G
D
R
V
L
F
M
D
G
-------------------------------------------------------------------------------------------------------------------------------------------
54
PsiBlast_CBE
57.06
38%
-67
- C1 -
-
3C41
2
?
K:
[2-213]
--
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
----
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
---------
K
A
-
K
D
T
N
L
N
K
V
R
-
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
-
T
L
A
P
M
K
V
---
R
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
K
-
A
H
-
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
-
E
-
M
G
F
A
-
R
-
E
V
G
D
R
V
L
F
M
D
G
-------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
57.05
39%
-66
- C1 -
-
2OLK
1
?
A:
[22-234]
-
L
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
----
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
---------
K
A
-
K
D
T
N
L
N
K
V
R
-
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
-
T
L
A
P
M
K
V
---
R
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
K
-
A
H
-
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
-
E
-
M
G
F
A
-
R
-
E
V
G
D
R
V
L
F
M
D
G
-------------------------------------------------------------------------------------------------------------------------------------------
36
PsiBlast_CBE
56.51
39%
-65
- C1 -
-
3C4J
2
?
A:
[22-234]
-
L
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
----
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
---------
K
A
-
K
D
T
N
L
N
K
V
R
-
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
-
T
L
A
P
M
K
V
---
R
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
K
-
A
H
-
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
-
E
-
M
G
F
A
-
R
-
E
V
G
D
R
V
L
F
M
D
G
-------------------------------------------------------------------------------------------------------------------------------------------
38
PsiBlast_CBE
55.50
39%
-62
- C1 -
-
2Q0H
3
?
A:
[23-234]
--
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
----
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
---------
K
A
-
K
D
T
N
L
N
K
V
R
-
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
-
T
L
A
P
M
K
V
---
R
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
K
-
A
H
-
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
-
E
-
M
G
F
A
-
R
-
E
V
G
D
R
V
L
F
M
D
G
-------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
54.76
39%
-69
- C1 -
-
2OLJ
3
?
A:
[22-234]
-
L
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
----
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
---------
K
A
-
K
D
T
N
L
N
K
V
R
-
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
-
T
L
A
P
M
K
V
---
R
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
K
-
A
H
-
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
-
E
-
M
G
F
A
-
R
-
E
V
G
D
R
V
L
F
M
D
G
-------------------------------------------------------------------------------------------------------------------------------------------
55
PsiBlast_CBE
54.56
38%
-60
- C1 -
-
3C41
2
?
J:
[2-213]
--
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
----
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
---------
K
A
-
K
D
T
N
L
N
K
V
R
-
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
-
T
L
A
P
M
K
V
---
R
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
K
-
A
H
-
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
-
E
-
M
G
F
A
-
R
-
E
V
G
D
R
V
L
F
M
D
G
-------------------------------------------------------------------------------------------------------------------------------------------
87
PsiBlast_CBE
52.72
36%
-17
- C1 -
-
1B0U
1
HISP_SALTY
A:
[20-225]
---------------------
E
V
L
K
G
V
S
L
Q
A
R
A
G
D
V
I
S
I
I
G
S
S
G
S
G
K
S
T
F
L
R
C
I
N
F
L
E
K
P
S
E
G
A
I
I
V
N
G
Q
N
I
N
L
V
R
D
KDGQ
L
K
V
A
D
K
N
Q
L
R
L
L
R
T
R
L
T
M
V
F
Q
H
F
N
L
W
S
H
M
T
V
L
E
N
V
M
E
A
-
P
I
Q
V
---
L
G
L
S
K
H
D
A
R
E
R
A
L
K
Y
L
A
K
V
G
I
D
E
R
-
A
Q
G
K
Y
P
V
H
L
S
G
G
Q
Q
Q
R
V
S
I
A
R
A
L
A
M
E
P
D
V
L
L
F
D
E
P
T
S
A
L
D
P
E
L
V
G
E
V
L
R
I
M
Q
Q
L
A
E
E
-
G
K
T
M
V
V
V
T
H
-
E
-
M
G
F
A
-
R
-
H
V
S
S
H
V
I
F
----------------------------------------------------------------------------------------------------------------------------------------------
37
PsiBlast_CBE
51.01
39%
-70
- C1 -
-
2Q0H
3
?
B:
[22-234]
-
L
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
----
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
---------
K
A
-
K
D
T
N
L
N
K
V
R
-
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
-
T
L
A
P
M
K
V
---
R
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
K
-
A
H
-
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
-
E
-
M
G
F
A
-
R
-
E
V
G
D
R
V
L
F
M
D
G
-------------------------------------------------------------------------------------------------------------------------------------------