@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : spr0728: (2017-12-28 )
MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGKSTLLRSMNLLEEATKGKVIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENITLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPDVLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVVVEDGTPEQIFEQTQEQRTKDFLRKVL
Atome Classification :
(38 SA)
.........10........----20........30........40........50...----.....60.....-------------...70--..--------......--.80.....--...90........100.....-.--.110-.--------------......120-----.....----------...130.-...-...140.......150.....-..160.......170.......180.-...-.-..190.......200.......210.-......220.......230--.......240..---
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MT
E
T
L
I
K
I
E
N
L
H
K
SF
G
K
N
E
----
V
LKGI
N
L
E
I
KRG
E
V
V
V
I
IGPSGS
G
K
S
T
L
L
R
S
M
N
L
L
----
E
E
ATKG
K
V
I
F
EG-------------VDIT---DK--------K
N
D
L
F
A
--
M
R
E
K
M
G
M
V
--
F
Q
Q
F
NLFPN
M
T
V
M
ENITLSPI-K--TKG
E
-
S
--------------
R
E
V
A
E
K
R
A
------
Q
E
L
L
E
----------KVGLPDK-ADA-YPQSLSGGQQ
Q
R
I
A
IARGLAM-EP
D
V
L
L
FDEPTSAL
D
P
E
M
V
G
E
V
L
A
V
M
-
Q
D
L
-
A
-KSG
M
T
M
V
I
V
THEMG
F
A
R
E
V
AD
R
V
I
F
M
-AD
G
V
V
VEDG
T
P
E
Q
I
F
E
Q
T
Q
--
E
Q
R
T
K
D
F
L
R
K
VL---
13
PsiBlast_PDB
95.17
63%
-107
- C1 -
-
4U02
-
?
A:
[2-242]
--
E
P
I
I
R
I
R
N
L
H
K
W
F
G
P
L
H
----
V
L
K
G
I
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
R
L
----
E
D
F
Q
E
G
E
V
V
V
D
G
-------------
L
S
V
K
---
D
D
--------
R
A
-
L
R
E
--
I
R
R
E
V
G
M
V
--
F
Q
Q
F
N
L
F
P
H
M
T
V
L
E
N
V
T
L
A
P
M
-
R
--
V
R
R
W
-
P
--------------
R
E
K
A
E
K
K
A
------
L
E
L
L
E
----------
R
V
G
I
L
D
Q
-
A
R
K
-
Y
P
A
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
D
V
M
-
R
D
L
-
A
-
Q
G
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
A
D
R
V
V
F
M
-
D
G
G
Q
I
V
E
E
G
R
P
E
E
I
F
T
R
P
K
--
E
E
R
T
R
S
F
L
Q
R
V
L
---
27
PsiBlast_CBE
94.83
63%
-122
- C1 -
-
2OLK
1
?
D:
[24-263]
----
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
E
----
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
----
E
D
F
D
E
G
E
I
I
I
D
G
-------------
I
N
L
K
---
A
K
--------
D
T
N
L
N
K
--
V
R
E
E
V
G
M
V
--
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
-
K
--
V
R
K
W
-
P
--------------
R
E
K
A
E
A
K
A
------
M
E
L
L
D
----------
K
V
G
L
K
D
K
-
A
H
A
-
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
-
K
Q
L
-
A
-
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
-
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
--
H
E
R
T
K
A
F
L
S
K
V
F
---
6
PsiBlast_PDB
94.73
63%
-121
- C1 -
-
3C4J
2
?
A:
[24-263]
----
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
E
----
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
----
E
D
F
D
E
G
E
I
I
I
D
G
-------------
I
N
L
K
---
A
K
--------
D
T
N
L
N
K
--
V
R
E
E
V
G
M
V
--
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
-
K
--
V
R
K
W
-
P
--------------
R
E
K
A
E
A
K
A
------
M
E
L
L
D
----------
K
V
G
L
K
D
K
-
A
H
A
-
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
-
K
Q
L
-
A
-
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
-
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
--
H
E
R
T
K
A
F
L
S
K
V
F
---
29
PsiBlast_CBE
94.40
63%
-121
- C1 -
-
2OLK
2
?
B:
[24-263]
----
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
E
----
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
----
E
D
F
D
E
G
E
I
I
I
D
G
-------------
I
N
L
K
---
A
K
--------
D
T
N
L
N
K
--
V
R
E
E
V
G
M
V
--
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
-
K
--
V
R
K
W
-
P
--------------
R
E
K
A
E
A
K
A
------
M
E
L
L
D
----------
K
V
G
L
K
D
K
-
A
H
A
-
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
-
K
Q
L
-
A
-
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
-
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
--
H
E
R
T
K
A
F
L
S
K
V
F
---
12
PsiBlast_PDB
94.33
63%
-113
- C1 -
-
4U00
1
?
A:
[3-242]
---
P
I
I
R
I
R
N
L
H
K
W
F
G
P
L
H
----
V
L
K
G
I
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
R
L
----
E
D
F
Q
E
G
E
V
V
V
D
G
-------------
L
S
V
K
---
D
D
--------
R
A
-
L
R
E
--
I
R
R
E
V
G
M
V
--
F
Q
Q
F
N
L
F
P
H
M
T
V
L
E
N
V
T
L
A
P
M
-
R
--
V
R
R
W
-
P
--------------
R
E
K
A
E
K
K
A
------
L
E
L
L
E
----------
R
V
G
I
L
D
Q
-
A
R
K
-
Y
P
A
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
D
V
M
-
R
D
L
-
A
-
Q
G
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
A
D
R
V
V
F
M
-
D
G
G
Q
I
V
E
E
G
R
P
E
E
I
F
T
R
P
K
--
E
E
R
T
R
S
F
L
Q
R
V
L
---
28
PsiBlast_CBE
94.29
63%
-125
- C1 -
-
2OLK
1
?
C:
[24-263]
----
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
E
----
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
----
E
D
F
D
E
G
E
I
I
I
D
G
-------------
I
N
L
K
---
A
K
--------
D
T
N
L
N
K
--
V
R
E
E
V
G
M
V
--
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
-
K
--
V
R
K
W
-
P
--------------
R
E
K
A
E
A
K
A
------
M
E
L
L
D
----------
K
V
G
L
K
D
K
-
A
H
A
-
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
-
K
Q
L
-
A
-
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
-
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
--
H
E
R
T
K
A
F
L
S
K
V
F
---
2
PsiBlast_PDB
94.16
63%
-130
- C1 -
-
2OLJ
3
?
A:
[24-263]
----
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
E
----
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
----
E
D
F
D
E
G
E
I
I
I
D
G
-------------
I
N
L
K
---
A
K
--------
D
T
N
L
N
K
--
V
R
E
E
V
G
M
V
--
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
-
K
--
V
R
K
W
-
P
--------------
R
E
K
A
E
A
K
A
------
M
E
L
L
D
----------
K
V
G
L
K
D
K
-
A
H
A
-
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
-
K
Q
L
-
A
-
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
-
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
--
H
E
R
T
K
A
F
L
S
K
V
F
---
1
PsiBlast_PDB
93.60
63%
-115
- C1 -
-
3C41
2
?
J:
[3-242]
----
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
E
----
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
----
E
D
F
D
E
G
E
I
I
I
D
G
-------------
I
N
L
K
---
A
K
--------
D
T
N
L
N
K
--
V
R
E
E
V
G
M
V
--
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
-
K
--
V
R
K
W
-
P
--------------
R
E
K
A
E
A
K
A
------
M
E
L
L
D
----------
K
V
G
L
K
D
K
-
A
H
A
-
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
-
K
Q
L
-
A
-
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
-
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
--
H
E
R
T
K
A
F
L
S
K
V
F
---
3
PsiBlast_PDB
93.48
63%
-126
- C1 -
-
2OLK
1
?
A:
[24-263]
----
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
E
----
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
----
E
D
F
D
E
G
E
I
I
I
D
G
-------------
I
N
L
K
---
A
K
--------
D
T
N
L
N
K
--
V
R
E
E
V
G
M
V
--
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
-
K
--
V
R
K
W
-
P
--------------
R
E
K
A
E
A
K
A
------
M
E
L
L
D
----------
K
V
G
L
K
D
K
-
A
H
A
-
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
-
K
Q
L
-
A
-
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
-
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
--
H
E
R
T
K
A
F
L
S
K
V
F
---
32
PsiBlast_CBE
93.20
63%
-125
- C1 -
-
4YMU
1
?
A:
[1-240]
----
M
I
F
V
N
D
V
Y
K
N
F
G
S
L
E
----
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
----
E
E
P
T
K
G
E
V
F
I
D
G
-------------
V
K
I
N
---
N
G
--------
K
V
N
I
N
K
--
V
R
Q
K
V
G
M
V
--
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
L
A
P
V
-
K
--
V
K
K
M
-
N
--------------
K
K
E
A
E
E
L
A
------
V
D
L
L
A
----------
K
V
G
L
L
D
K
-
K
D
Q
-
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
-
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
-
K
Q
L
-
A
-
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
-
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
--
N
E
R
T
R
E
F
L
S
K
I
L
---
5
PsiBlast_PDB
92.87
63%
-121
- C1 -
-
2Q0H
3
?
A:
[24-263]
----
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
E
----
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
----
E
D
F
D
E
G
E
I
I
I
D
G
-------------
I
N
L
K
---
A
K
--------
D
T
N
L
N
K
--
V
R
E
E
V
G
M
V
--
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
-
K
--
V
R
K
W
-
P
--------------
R
E
K
A
E
A
K
A
------
M
E
L
L
D
----------
K
V
G
L
K
D
K
-
A
H
A
-
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
-
K
Q
L
-
A
-
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
-
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
--
H
E
R
T
K
A
F
L
S
K
V
F
---
4
PsiBlast_PDB
92.83
63%
-127
- C1 -
-
2OUK
-
?
A:
[24-263]
----
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
E
----
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
----
E
D
F
D
E
G
E
I
I
I
D
G
-------------
I
N
L
K
---
A
K
--------
D
T
N
L
N
K
--
V
R
E
E
V
G
M
V
--
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
-
K
--
V
R
K
W
-
P
--------------
R
E
K
A
E
A
K
A
------
M
E
L
L
D
----------
K
V
G
L
K
D
K
-
A
H
A
-
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
-
K
Q
L
-
A
-
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
-
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
--
H
E
R
T
K
A
F
L
S
K
V
F
---
31
PsiBlast_CBE
92.69
63%
-121
- C1 -
-
4YMV
1
?
A:
[1-240]
----
M
I
F
V
N
D
V
Y
K
N
F
G
S
L
E
----
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
----
E
E
P
T
K
G
E
V
F
I
D
G
-------------
V
K
I
N
---
N
G
--------
K
V
N
I
N
K
--
V
R
Q
K
V
G
M
V
--
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
L
A
P
V
-
K
--
V
K
K
M
-
N
--------------
K
K
E
A
E
E
L
A
------
V
D
L
L
A
----------
K
V
G
L
L
D
K
-
K
D
Q
-
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
-
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
-
K
Q
L
-
A
-
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
-
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
--
N
E
R
T
R
E
F
L
S
K
I
L
---
22
PsiBlast_CBE
92.62
63%
-124
- C1 -
-
3C4J
2
?
B:
[24-263]
----
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
E
----
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
----
E
D
F
D
E
G
E
I
I
I
D
G
-------------
I
N
L
K
---
A
K
--------
D
T
N
L
N
K
--
V
R
E
E
V
G
M
V
--
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
-
K
--
V
R
K
W
-
P
--------------
R
E
K
A
E
A
K
A
------
M
E
L
L
D
----------
K
V
G
L
K
D
K
-
A
H
A
-
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
-
K
Q
L
-
A
-
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
-
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
--
H
E
R
T
K
A
F
L
S
K
V
F
---
23
PsiBlast_CBE
92.04
63%
-128
- C1 -
-
2Q0H
3
?
B:
[24-263]
----
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
E
----
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
----
E
D
F
D
E
G
E
I
I
I
D
G
-------------
I
N
L
K
---
A
K
--------
D
T
N
L
N
K
--
V
R
E
E
V
G
M
V
--
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
-
K
--
V
R
K
W
-
P
--------------
R
E
K
A
E
A
K
A
------
M
E
L
L
D
----------
K
V
G
L
K
D
K
-
A
H
A
-
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
-
K
Q
L
-
A
-
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
-
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
--
H
E
R
T
K
A
F
L
S
K
V
F
---
30
PsiBlast_CBE
91.25
63%
-119
- C1 -
-
2OLJ
2
?
B:
[24-263]
----
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
E
----
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
----
E
D
F
D
E
G
E
I
I
I
D
G
-------------
I
N
L
K
---
A
K
--------
D
T
N
L
N
K
--
V
R
E
E
V
G
M
V
--
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
-
K
--
V
R
K
W
-
P
--------------
R
E
K
A
E
A
K
A
------
M
E
L
L
D
----------
K
V
G
L
K
D
K
-
A
H
A
-
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
-
K
Q
L
-
A
-
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
-
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
--
H
E
R
T
K
A
F
L
S
K
V
F
---
21
PsiBlast_CBE
90.96
63%
-122
- C1 -
-
3C41
2
?
K:
[3-242]
----
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
E
----
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
----
E
D
F
D
E
G
E
I
I
I
D
G
-------------
I
N
L
K
---
A
K
--------
D
T
N
L
N
K
--
V
R
E
E
V
G
M
V
--
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
-
K
--
V
R
K
W
-
P
--------------
R
E
K
A
E
A
K
A
------
M
E
L
L
D
----------
K
V
G
L
K
D
K
-
A
H
A
-
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
-
K
Q
L
-
A
-
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
-
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
--
H
E
R
T
K
A
F
L
S
K
V
F
---
10
PsiBlast_PDB
90.63
63%
-122
- C1 -
-
4YMV
1
?
J:
[1-240]
----
M
I
F
V
N
D
V
Y
K
N
F
G
S
L
E
----
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
----
E
E
P
T
K
G
E
V
F
I
D
G
-------------
V
K
I
N
---
N
G
--------
K
V
N
I
N
K
--
V
R
Q
K
V
G
M
V
--
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
L
A
P
V
-
K
--
V
K
K
M
-
N
--------------
K
K
E
A
E
E
L
A
------
V
D
L
L
A
----------
K
V
G
L
L
D
K
-
K
D
Q
-
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
-
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
-
K
Q
L
-
A
-
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
-
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
--
N
E
R
T
R
E
F
L
S
K
I
L
---
9
PsiBlast_PDB
90.38
63%
-121
- C1 -
-
4YMU
1
?
J:
[1-240]
----
M
I
F
V
N
D
V
Y
K
N
F
G
S
L
E
----
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
----
E
E
P
T
K
G
E
V
F
I
D
G
-------------
V
K
I
N
---
N
G
--------
K
V
N
I
N
K
--
V
R
Q
K
V
G
M
V
--
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
L
A
P
V
-
K
--
V
K
K
M
-
N
--------------
K
K
E
A
E
E
L
A
------
V
D
L
L
A
----------
K
V
G
L
L
D
K
-
K
D
Q
-
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
-
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
-
K
Q
L
-
A
-
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
-
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
--
N
E
R
T
R
E
F
L
S
K
I
L
---
7
PsiBlast_PDB
89.26
63%
-122
- C1 -
-
4YMS
-
?
J:
[1-240]
----
M
I
F
V
N
D
V
Y
K
N
F
G
S
L
E
----
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
----
E
E
P
T
K
G
E
V
F
I
D
G
-------------
V
K
I
N
---
N
G
--------
K
V
N
I
N
K
--
V
R
Q
K
V
G
M
V
--
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
L
A
P
V
-
K
--
V
K
K
M
-
N
--------------
K
K
E
A
E
E
L
A
------
V
D
L
L
A
----------
K
V
G
L
L
D
K
-
K
D
Q
-
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
-
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
-
K
Q
L
-
A
-
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
-
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
--
N
E
R
T
R
E
F
L
S
K
I
L
---
14
PsiBlast_PDB
77.98
52%
-5
- C1 -
-
1B0U
1
HISP_SALTY
A:
[5-257]
---
N
K
L
H
V
I
D
L
H
K
R
Y
G
G
H
E
----
V
L
K
G
V
S
L
Q
A
R
A
G
D
V
I
S
I
I
G
S
S
G
S
G
K
S
T
F
L
R
C
I
N
F
L
----
E
K
P
S
E
G
A
I
I
V
N
G
-------------
Q
N
I
N
L
V
R
D
K
DGQLKVAD
K
N
Q
L
R
L
--
L
R
T
R
L
T
M
V
--
F
Q
H
F
N
L
W
S
H
M
T
V
L
E
N
V
M
E
A
P
I
-
Q
--
V
L
G
L
-
S
--------------
K
H
D
A
R
E
R
A
------
L
K
Y
L
A
----------
K
V
G
I
D
E
R
-
A
Q
G
K
Y
P
V
H
L
S
G
G
Q
Q
Q
R
V
S
I
A
R
A
L
A
M
-
E
P
D
V
L
L
F
D
E
P
T
S
A
L
D
P
E
L
V
G
E
V
L
R
I
M
-
Q
Q
L
-
A
-
E
E
G
K
T
M
V
V
V
T
H
E
M
G
F
A
R
H
V
S
S
H
V
I
F
L
-
H
Q
G
K
I
E
E
E
G
D
P
E
Q
V
F
G
N
P
Q
--
S
P
R
L
Q
Q
F
L
K
G
S
L
---
94
PsiBlast_CBE
60.60
36%
-107
- C1 -
-
3FVQ
2
FBPC_NEIG1
A:
[2-234]
-
T
A
A
L
-
H
I
G
H
L
S
K
S
F
Q
N
T
P
----
V
L
N
D
I
S
L
S
L
D
P
G
E
I
L
F
I
I
G
A
S
G
C
G
K
T
T
L
L
R
C
L
A
G
F
----
E
Q
P
D
S
G
E
I
S
L
S
G
-------------
K
T
I
F
---
S
K
--------
N
T
N
L
P
V
--
R
E
R
R
L
G
Y
L
--
V
Q
E
G
V
L
F
P
H
L
T
V
Y
R
N
I
A
Y
G
L
G
-
N
--
G
K
G
R
-
T
--------------
A
Q
-
E
R
Q
R
I
------
E
A
M
L
E
----------
L
T
G
I
S
E
L
-
A
G
R
-
Y
P
H
E
L
S
G
G
Q
Q
Q
R
A
A
L
A
R
A
L
A
P
-
D
P
E
L
I
L
L
D
E
P
F
S
A
L
D
E
Q
L
R
R
Q
I
R
E
D
M
I
A
A
L
-
R
-
A
N
G
K
S
A
V
F
V
S
H
D
R
E
E
A
L
Q
Y
A
D
R
I
A
V
M
-
K
Q
G
R
I
L
Q
T
A
S
P
H
E
L
Y
R
Q
-------------------
93
PsiBlast_CBE
59.92
36%
-106
- C1 -
-
3FVQ
2
FBPC_NEIG1
B:
[2-229]
-
T
A
A
L
-
H
I
G
H
L
S
K
S
F
Q
N
T
P
----
V
L
N
D
I
S
L
S
L
D
P
G
E
I
L
F
I
I
G
A
S
G
C
G
K
T
T
L
L
R
C
L
A
G
F
----
E
Q
P
D
S
G
E
I
S
L
S
G
-------------
K
T
I
F
---
S
K
--------
N
T
N
L
P
V
--
R
E
R
R
L
G
Y
L
--
V
Q
E
G
V
L
F
P
H
L
T
V
Y
R
N
I
A
Y
G
L
G
-
N
--
G
K
G
R
-
T
--------------
A
Q
-
E
R
Q
R
I
------
E
A
M
L
E
----------
L
T
G
I
S
E
L
-
A
G
R
-
Y
P
H
E
L
S
G
G
Q
Q
Q
R
A
A
L
A
R
A
L
A
P
-
D
P
E
L
I
L
L
D
E
P
F
S
A
L
D
E
Q
L
R
R
Q
I
R
E
D
M
I
A
A
L
-
R
-
A
N
G
K
S
A
V
F
V
S
H
D
R
E
E
A
L
Q
Y
A
D
R
I
A
V
M
-
K
Q
G
R
I
L
Q
T
A
S
P
H
E
L
Y
R
Q
-------------------
51
PsiBlast_CBE
59.73
38%
-113
- C1 -
-
1VCI
1
?
A:
[13-237]
-----
V
K
L
E
N
L
T
K
R
F
G
N
F
T
----
A
V
N
K
L
N
L
T
I
K
D
G
E
F
L
V
L
L
G
P
S
G
C
G
K
T
T
T
L
R
M
I
A
G
L
----
E
E
P
T
E
G
R
I
Y
F
G
D
-------------
R
D
V
T
---------------
Y
L
P
P
--
K
D
R
N
I
S
M
V
--
F
Q
------
H
M
T
V
Y
E
N
I
A
F
-
P
L
-----
K
K
F
-
P
--------------
K
D
E
I
D
K
R
V
------
R
W
A
A
E
----------
L
L
Q
I
E
E
L
-
L
N
R
-
Y
P
A
Q
L
S
G
G
Q
R
Q
R
V
A
V
A
R
A
I
V
V
-
E
P
D
V
L
L
M
D
E
P
L
S
N
L
D
A
K
L
R
V
A
M
R
A
E
I
-
K
K
L
Q
Q
-
K
L
K
V
T
T
I
Y
V
T
H
D
Q
V
E
A
M
T
M
G
D
R
I
A
V
M
-
N
R
G
Q
L
L
Q
I
G
S
P
T
E
V
Y
---------------------
168
Fugue
59.46
50%
5
- C1 -
-
1B0U
1
HISP_SALTY
A:
[5-261]
---
N
K
L
H
V
I
D
L
H
K
R
Y
G
G
--HEV-
L
K
-
G
V
S
L
Q
A
R
A
G
D
V
I
S
I
I
G
S
S
G
S
G
K
S
T
F
L
R
C
I
N
F
L
EKPS----
E
G
A
I
I
V
N
G
QNI
N
L
V
R
D
KDGQL
K
V
A
D
---
K
N
--------
Q
L
R
L
L
R
--
T
-
R
-
L
T
M
V
--
F
Q
H
F
N
L
W
S
H
M
T
V
L
E
N
V
M
E
A
P
I
-
Q
VL--
G
L
-
S
--------------
K
H
D
A
R
E
R
A
------
L
K
Y
L
A
K
V
GIDERAQG----------
K
-
Y
P
V
H
L
S
G
G
Q
Q
Q
R
V
S
I
A
R
A
L
A
M
E-
P
D
V
L
L
F
D
E
P
T
S
A
L
D
P
E
L
V
G
E
V
L
R
I
M
-
Q
Q
L
-
A
-
E
E
G
K
T
M
V
V
V
T
H
E
M
G
F
A
R
H
V
S
S
H
V
I
F
L
H
-
Q
G
K
I
E
E
E
G
D
P
E
Q
V
F
G
N
P
-QS
P
R
L
Q
Q
F
L
K
G
S
L
K
KLE
143
HHSearch
59.05
36%
-112
- C1 -
-
3FVQ
2
FBPC_NEIG1
B:
[2-230]
--
T
A
A
L
H
I
G
H
L
S
K
S
F
Q
N
T
P
----
V
L
N
D
I
S
L
S
L
D
P
G
E
I
L
F
I
I
G
A
S
G
C
G
K
T
T
L
L
R
C
L
A
G
F
----
E
Q
P
D
S
G
E
I
S
L
S
G
-------------
K
T
I
F
---
S
K
--------
N
T
N
L
P
V
--
R
E
R
R
L
G
Y
L
--
V
Q
E
G
V
L
F
P
H
L
T
V
Y
R
N
I
A
Y
G
L
G
-
N
--
G
K
G
--
R
--------------
T
A
Q
E
R
Q
R
I
------
E
A
M
L
E
----------
L
T
G
I
S
E
L
-
A
G
R
-
Y
P
H
E
L
S
G
G
Q
Q
Q
R
A
A
L
A
R
A
L
A
P
-
D
P
E
L
I
L
L
D
E
P
F
S
A
L
D
E
Q
L
R
R
Q
I
R
E
D
M
-
I
A
A
-
L
R
A
N
G
K
S
A
V
F
V
S
H
D
R
E
E
A
L
Q
Y
A
D
R
I
A
V
M
-
K
Q
G
R
I
L
Q
T
A
S
P
H
E
L
Y
R
Q
P
------------------
130
PsiBlast_CBE
52.79
31%
-56
- C1 -
-
1G6H
1
LIVG_METJA
A:
[4-239]
-
T
M
E
I
L
R
T
E
N
I
V
K
Y
F
G
E
F
K
----
A
L
D
G
V
S
I
S
V
N
K
G
D
V
T
L
I
I
G
P
N
G
S
G
K
S
T
L
I
N
V
I
T
G
F
----
L
K
A
D
E
G
R
V
Y
F
E
N
-------------
K
D
I
T
---
N
K
--------
E
P
---
A
--
E
L
Y
H
Y
G
I
V
R
T
F
Q
T
P
Q
P
L
K
E
M
T
V
L
E
N
L
L
I
G
E
I
----
C
P
G
E
-
S
P
L
N
S
L
F
Y
KKWIPKE
E
E
M
V
E
K
-
A
------
F
K
I
L
E
----------
F
L
K
L
S
H
L
-
Y
D
R
-
K
A
G
E
L
S
G
G
Q
M
K
L
V
E
I
G
R
A
L
M
T
-
N
P
K
M
I
V
M
D
E
P
I
A
G
V
A
P
G
L
A
H
D
I
F
N
H
V
-
L
E
L
-
K
-
A
K
G
I
T
F
L
I
I
E
H
R
L
D
I
V
L
N
Y
I
D
H
L
Y
V
M
-
F
N
G
Q
I
I
A
E
G
R
G
E
E
-----------------------
49
PsiBlast_CBE
51.09
41%
38
- C1 -
-
3TIF
4
Y796_METJA
B:
[1-223]
----
M
V
K
L
K
N
V
T
K
T
Y
K
M
G
E
EIIY
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
----
D
K
P
T
E
G
E
V
Y
I
D
N
-------------
I
K
T
N
---
D
L
--------
D
D
D
E
L
T
KI
R
R
D
K
I
G
F
V
--
F
Q
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
E
L
P
L
I
F
K
--
Y
R
G
A
M
S
--------------
G
E
E
R
R
K
R
A
------
L
E
C
L
K
----------
M
A
E
L
E
E
R
F
A
N
H
-
K
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
-
N
P
P
I
I
L
A
D
Q
P
T
W
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
-
K
K
L
-
N
E
E
D
G
K
T
V
V
V
V
T
H
D
I
N
V
A
R
-
F
G
E
R
I
I
Y
L
-
K
D
G
E
V
-------------------------------
102
PsiBlast_CBE
43.35
36%
-34
- C1 -
-
2FF7
1
A:
[24-233]
-----------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
----
Y
I
P
E
N
G
Q
V
L
I
D
G
-------------
H
D
L
A
-------------
L
A
D
P
N
W
--
L
R
R
Q
V
G
V
V
--
L
Q
D
-
N
V
L
L
N
R
S
I
I
D
N
I
S
L
A
N
P
-
G
--
M
S
V
E
-
K
--------------
V
I
Y
A
A
K
L
A
GA
H
D
F
I
S
E
L
R
E
------------
G
Y
N
T
I
-
V
G
E
-
Q
G
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
-
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
-
H
K
I
-
C
-
K
-
G
R
T
V
I
I
I
A
H
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
-
E
K
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
-------------------
99
PsiBlast_CBE
43.32
36%
-35
- C1 -
-
2PMK
1
A:
[20-229]
-----------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
----
Y
I
P
E
N
G
Q
V
L
I
D
G
-------------
H
D
L
A
-------------
L
A
D
P
N
W
--
L
R
R
Q
V
G
V
V
--
L
Q
D
-
N
V
L
L
N
R
S
I
I
D
N
I
S
L
A
N
P
-
G
--
M
S
V
E
-
K
--------------
V
I
Y
A
A
K
L
A
GA
H
D
F
I
S
E
L
R
E
------------
G
Y
N
T
I
-
V
G
E
-
Q
G
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
-
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
-
H
K
I
-
C
-
K
-
G
R
T
V
I
I
I
A
H
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
-
E
K
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
-------------------
122
PsiBlast_CBE
41.99
36%
-25
- C1 -
-
2FGK
2
HLYBP_ECOLX
A:
[24-233]
-----------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
----
Y
I
P
E
N
G
Q
V
L
I
D
G
-------------
H
D
L
A
---
L
A
----------
D
P
N
W
--
L
R
R
Q
V
G
V
V
--
L
Q
D
-
N
V
L
L
N
R
S
I
I
D
N
I
S
L
A
N
P
-
G
--
M
S
V
E
-
K
--------------
V
I
Y
A
A
K
L
A
GA
H
D
F
I
S
E
L
R
E
------------
G
Y
N
T
I
-
V
G
E
-
Q
G
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
-
N
P
K
I
L
I
F
D
Q
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
-
H
K
I
-
C
-
K
-
G
R
T
V
I
I
I
A
H
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
-
E
K
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
-------------------
138
PsiBlast_CBE
40.87
36%
-31
- C1 -
-
2FFA
2
A:
[24-233]
-----------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
----
Y
I
P
E
N
G
Q
V
L
I
D
G
-------------
H
D
L
A
---
L
A
----------
D
P
N
W
--
L
R
R
Q
V
G
V
V
--
L
Q
D
-
N
V
L
L
N
R
S
I
I
D
N
I
S
L
A
N
P
-
G
--
M
S
V
E
-
K
--------------
V
I
Y
A
A
K
L
A
GA
H
D
F
I
S
E
L
R
E
------------
G
Y
N
T
I
-
V
G
E
-
Q
G
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
-
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
-
H
K
I
-
C
-
K
-
G
R
T
V
I
I
I
A
A
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
-
E
K
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
-------------------
120
PsiBlast_CBE
40.33
36%
-24
- C1 -
-
2FGK
2
HLYBP_ECOLX
C:
[24-233]
-----------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
----
Y
I
P
E
N
G
Q
V
L
I
D
G
-------------
H
D
L
A
---
L
A
----------
D
P
N
W
--
L
R
R
Q
V
G
V
V
--
L
Q
D
-
N
V
L
L
N
R
S
I
I
D
N
I
S
L
A
N
P
-
G
--
M
S
V
E
-
K
--------------
V
I
Y
A
A
K
L
A
GAHDFI
S
E
L
R
E
------------
G
Y
N
T
I
-
V
G
E
-
Q
G
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
-
N
P
K
I
L
I
F
D
Q
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
-
H
K
I
-
C
-
K
-
G
R
T
V
I
I
I
A
H
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
-
E
K
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
-------------------
134
PsiBlast_CBE
39.84
36%
-27
- C1 -
-
2FGJ
2
D:
[24-233]
-----------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
----
Y
I
P
E
N
G
Q
V
L
I
D
G
-------------
H
D
L
A
---
L
A
----------
D
P
N
W
--
L
R
R
Q
V
G
V
V
--
L
Q
D
-
N
V
L
L
N
R
S
I
I
D
N
I
S
L
A
N
P
-
G
--
M
S
V
E
-
K
--------------
V
I
Y
A
A
K
L
A
GAHDFI
S
E
L
R
E
------------
G
Y
N
T
I
-
V
G
E
-
Q
G
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
-
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
-
H
K
I
-
C
-
K
-
G
R
T
V
I
I
I
A
A
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
-
E
K
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
-------------------
142
PsiBlast_CBE
38.73
36%
-26
- C1 -
-
1XEF
2
HLYBP_ECOLX
A:
[18-227]
-----------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
----
Y
I
P
E
N
G
Q
V
L
I
D
G
-------------
H
D
L
A
---
L
A
----------
D
P
N
W
--
L
R
R
Q
V
G
V
V
--
L
Q
D
-
N
V
L
L
N
R
S
I
I
D
N
I
S
L
A
N
P
-
G
--
M
S
V
E
-
K
--------------
V
I
Y
A
A
K
L
A
GA
H
D
F
I
S
E
L
R
E
------------
G
Y
N
T
I
-
V
G
E
-
Q
G
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
-
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
-
H
K
I
-
C
-
K
-
G
R
T
V
I
I
I
A
A
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
-
E
K
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
-------------------
119
PsiBlast_CBE
37.75
36%
-23
- C1 -
-
2FGK
2
D:
[24-233]
-----------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
----
Y
I
P
E
N
G
Q
V
L
I
D
G
-------------
H
D
L
A
---
L
A
----------
D
P
N
W
--
L
R
R
Q
V
G
V
V
--
L
Q
D
-
N
V
L
L
N
R
S
I
I
D
N
I
S
L
A
N
P
-
G
--
M
S
V
E
-
K
--------------
V
I
Y
A
A
K
L
A
GAHDFI
S
E
L
R
E
------------
G
Y
N
T
I
-
V
G
E
-
Q
G
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
-
N
P
K
I
L
I
F
D
Q
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
-
H
K
I
-
C
-
K
-
G
R
T
V
I
I
I
A
H
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
-
E
K
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
-------------------
137
PsiBlast_CBE
36.61
36%
-26
- C1 -
-
2FGJ
2
HLYBP_ECOLX
A:
[24-233]
-----------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
----
Y
I
P
E
N
G
Q
V
L
I
D
G
-------------
H
D
L
A
---
L
A
----------
D
P
N
W
--
L
R
R
Q
V
G
V
V
--
L
Q
D
-
N
V
L
L
N
R
S
I
I
D
N
I
S
L
A
N
P
-
G
--
M
S
V
E
-
K
--------------
V
I
Y
A
A
K
L
A
GA
H
D
F
I
S
E
L
R
E
------------
G
Y
N
T
I
-
V
G
E
-
Q
G
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
-
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
-
H
K
I
-
C
-
K
-
G
R
T
V
I
I
I
A
A
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
-
E
K
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
-------------------
121
PsiBlast_CBE
35.27
36%
-20
- C1 -
-
2FGK
2
HLYBP_ECOLX
B:
[24-233]
-----------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
----
Y
I
P
E
N
G
Q
V
L
I
D
G
-------------
H
D
L
A
---
L
A
----------
D
P
N
W
--
L
R
R
Q
V
G
V
V
--
L
Q
D
-
N
V
L
L
N
R
S
I
I
D
N
I
S
L
A
N
P
-
G
--
M
S
V
E
-
K
--------------
V
I
Y
A
A
K
L
A
GAHDFI
S
E
L
R
E
------------
G
Y
N
T
I
-
V
G
E
-
Q
G
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
-
N
P
K
I
L
I
F
D
Q
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
-
H
K
I
-
C
-
K
-
G
R
T
V
I
I
I
A
H
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
-
E
K
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
-------------------